vvEPA
United States
Environmental Protection
Agency
Contaminant Information Sheets for the
PCCL Chemicals Considered for CCL 3
-------
Office of Water (4607M)
EPA815-R-09-014
August 2009
www.epa.gov/safewater
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EPA815-R-09-014 Final CCL 3 Chemicals August 2009
EPA OGWDW Contaminant Information Sheets Page 1 of 1124
Contaminant Information Sheets for the PCCL Chemicals Considered for CCL 3
This File contains Contaminant Information Sheets for 561 chemical contaminants on the
Preliminary Contaminant Candidate List (PCCL 3). These sheets summarize information about
the chemicals that were considered during the analysis for the development of the final third
Contaminant Candidate List (CCL 3). The sheets are in alphabetical order. The first 106
Information Sheets are for the chemicals on the final CCL 3. (Note: there are 104 chemical
entries listed in the Federal Register Notice for the final CCL 3; cyanotoxins are listed as a
group. In this file, there are information sheets on three individual cyanotoxins that were
evaluated in the CCL 3 process (Anatoxin-a, Cylindrospermopsin, and Microcystin-LR)).
Following the CCL 3 chemicals, the Information Sheets for the remaining 455 chemicals on the
PCCL are presented in alphabetical order. Each information sheet is two pages in length. There
is an index/bookmark in this PDF file that can be used to negotiate the file. The bookmarks are
hyperlinked. You can find the contaminant name in the bookmark list, click on it, and the
hyperlink will take you to that file.
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EPA815-R-09-014 Final CCL 3 Chemicals August 2009
EPAOGWDW Contaminant Information Sheets Page 2 of 1124
This page intentionally left blank for double-sided printing
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1,1,1,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 3 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,1,1 ,2-Tetrachloroethane
9105
630206
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.03
0.03
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2006
Critical Effect
Mineralization of the kidneys in males, hepatic clear cell
change in females
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.1
0.026
C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1989
1989
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1
210
1
Y/N
Y/N
mg/L
ug/L
ug/L
2006
3-model Categorical Prediction
[_•?
HRL Ratio(s)
NC HRL/NCOD R1 90%: 67.7
CAR HRL/NCOD R1 90%: 0.323
Notes
Reference Dose
Reference Dose; Basis LOAEL =
89.3 mg/kg-d (NTP 1983)
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
EPA; RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
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1,1,1,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 4 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
16,956
24,127
31
51
0.18
0.21
0.06
0.2
9.2
18
0.59
0.5
3.1
1.55
9.2
18
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
Amount
Released
36
12,088
# PWSs/Sites
sampled
4
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.09
Number of
States
2
7
% PWSs/Sites
with detects
0.011
Units
States
States
States
Minimum value of
Detects
Non-cancer: 67.7
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.0644
Year
2004
2004
Maximum
value of
Detects
0.0275
0.0644
0.0644
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 0.323
Notes
Chemical intermed ate (NTP)
Value
60
93-399
2.66
2.70E-03
1,100
22
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
PBT; BST = biodegrades sometimes/recalcitrant
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1,1-Dichloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 5 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,1-Dichloroethane
2647
75343
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Decreased body weight gain
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0057
C
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
1,400
6.14
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
77 Li
HRL Ratio(s)
NC HRL/NCOD R1 90%: 250
CAR HRL/NCOD R1 90%: 1.1
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; basis NOAEL 71 4 mg/kg-d, UF = 3,000; Muralidhara, et al, 2001 .
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
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1,1-Dichloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 6 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
20,483
24,808
233
184
1.14
0.74
0.01
0.0013
500
159
1.2
1
5.6
3.8
27
25
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,350
Amount
Released
63
17,368
# PWSs/Sites
sampled
135
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3.103
Number of
States
3
5
% PWSs/Sites
with detects
0.008
Units
States
States
States
Minimum value of
Detects
Non-cancer: 250
Amount Range
>1M-10M
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
39
Year
2004
2004
Maximum
value of
Detects
0.05
0.316
5.6
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 1.1
Notes
Solvent (NTP)
Value
38
30
1.79
5.62E-03
5040
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
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1,2,3-Trichloropropane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 7 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1 ,2,3-Trichloropropane
3817
96184
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.006
0.006
0.006
0.06
5.71
22.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2006
1992
1987
Critical Effect
Alterations in clinical chemistry & reduction in RBC mass
Hepatic
Kidney, Ureter, Bladder - changes in bladder weight, Blood
- changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other esterases
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
7
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.2
42
0.005
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Prevalence Magnitude
3 6 Li
HRL Ratio(s)
NC HRL/NCOD R2 90%: 2.1
CAR HRL/NCOD R2 90% : 0.00025
Notes
Reference Dose
Reference Dose; NTP, 1983 ; rats; UF = 1,000; Basis NOAEL = 8 mg/kg-d
Reference Dose; F' 89
Reference Dose
Minimal Risk Level; Int-MRL; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER NOAEL
Lowest Observed Adverse Effect Level; 1 7 week oral study in rats; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-384,1993
Supplemental Data
HEAST
CACART, RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
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1,2,3-Trichloropropane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 8 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
17,392
24,088
44
19
0.25
0.079
0.1
0.03
112
3,000
0.92
0.5
6
20
112
3,000
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
4,309
Amount
Released
282
9,053
43
Units
Ibs/yr
Ibs/yr
Ibs/yr
1.0
Number of
States
1
2
0.05
Units
States
States
States
2.92
Year
2004
2004
0.4
0.97
2.92
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
Nominated data from NJDEP
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
NJ study: Detected in excess of health-based drinking water guidance value in 30 of 2,640 private wells and 1 1 of approximately 260 community
water systems between 1999 and 2004 in NJ SOC Waiver Program sampling.
Non-cancer: 2.1
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.00025
Notes
Paint ingredient (NTP)
Value
38
77-95
2.27
3.43E-04
1,750
25
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
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1,3-Butadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 9 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,3-Butadiene
4578
106990
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
10 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3.4
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.0103
Y/N
Y/N
ug/L
ug/L
Teratogen List
3-model Categorical Prediction
L
HRL Ratio(s)
No Water Data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Vol.71; 1999
EPA, IARC, CACART, OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
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1,3-Butadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 10 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
493
1,964,956
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
8
34
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rubber chemical (NTP)
Value
7-28
288
1.99
7.40E-02
735
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = biodegrades fast with acclimation
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1,3-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 11 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,3-Dinitrobenzene
4045
99650
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
0.0001
0.0001
0.0005
1.73
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
2006
1995
Critical Effect
Increased spleen weight
Hemato.
Endocrine - changes in spleen weight, Blood -
methemoglobinemia-carboxyhemoglobin
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.005
0.7
Y/N
Y/N
mg/L
ug/L
ug/L
2006
male
Prevalence Magnitude
1 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Cody etal., 1981; Rats; UF = 3,000; Basis NOAEL = 0.4 mg/kg-d
Reference Dose
Reference Dose; IRIS
Minimal Risk Level; Int-MRL; UF = 1 ,000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90 day oral study in rats; TOXID9 Toxicologist. (Soc. of
Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year
30,200,1996
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1,3-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 12 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
2
528,962
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
1
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (HSDB)
Value
38
150
1.49
4.90E-08
533
37
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
-------
1,4-Dioxane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 13 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,4-Dioxane
5539
123911
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.3
0.011
0.027
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1999
1987
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
700
3
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
9 8 L
HRL Ratio(s)
NC HRL/CAL DHS 90%: 92.1
CAR HRL/CAL DHS 90%: 0.395
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; ATSDR MRL-int = 0.6 mg/kg-d
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART; EPA; IARC; OEHHA; RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,4-Dioxane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 14 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental water data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
89,521
821,067
n
PWSs/Sites/Sa
mples
869
Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
89
Number of
States
7
22
%
PWSs/Sites/Sam
pies with
detects
10.2
Units
States
States
States
Minimum value of
Detects
0.001
Non-cancer: 92.1
Amount Range
>1M-10M
>1M-10M
Solvent (NTP); so
Value
1
-0.27
4.80E-06
1,000,000
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
46.2
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
2.1
90% of
Detects
7.6
Units
ug/L
Cancer: 0.395
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
vent stabilizer
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = biodegrades slowly
-------
17 alpha-Estradiol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 15 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
17 alpha-Estradio
81747
57910
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
9 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormonal response in post-menopausal
women
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/Kolpin MAX: 4.7
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
17 alpha-Estradiol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 16 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, et al., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
5.7
Units
States
States
States
Minimum value of
Detects
Non-cancer: 4.7
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.074
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.03
90% of
Detects
Units for Mag
data
ug/L
Notes
National Surface Water Reconnaissance
Kolpin, D.W., et al., 2002. Env. Sci. STechnol., 36(6), pp. 1202-1211.
Cancer:
Pharmaceutical, hormone
Value
38
3.94
3.9
11
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
1-Butanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 17 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Butanol
2563
71363
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
0.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Hypoactivity, ataxia
Behavioral - somnolence (general depressed activity)
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
700
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude , „ ,
10 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. EPA, 1986; Basis NOAEL = 125 mg/kg-d, UF = 1,000; oral study in rats.
Reference Dose
Reference Dose; IRIS
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30 day oral study in rats; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
135,3122,2002
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1-Butanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 18 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
22,011
17,648,846
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
20
44
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Paint solvent; chemical intermediate; food additive (HSDB)
Value
2.443
0.88
8.82E-06
63200
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades Fast
-------
2-Methoxyethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 19 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methoxyethanol
4803
109864
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Reproductive effects
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
21
Y/N
Y/N
ug/L
ug/L
Teratogen / developmental, male
Prevalence Magnitude
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Unpublished NTP study - Gulati, et al, 1990.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
UMD / CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Methoxyethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 20 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
14,390
153,774
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
3
16
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Consumer products; synthetic Cosmetics, Perfumes, Fragrances, Hair Preparations, Skin Lot on (NTP)
Value
1
-0.77
3.30E-07
1000000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades Fast with acclimat on
-------
2-Propen-1-ol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 21 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
2-Propen-1-ol
4596
107186
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
0.005
2.5
52
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Impaired renal function & increased relative liver,
spleen & kidney weights
Liver - liver function tests impaired, Blood - changes in
serum composition (e.g. TP, bilirubin, cholesterol),
Biochemical - Metabolism (Intermediary) - Plasma proteins
not involvinq coaqulation
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
8 8 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Carpanini et al., 1978; Rat; UF = 1,000; Basis NOAEL = 4.8 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; Rat; VCVGK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year -,121,1994
Supplemental Data
Rabbit; NTIS National Technical Information Serv ce. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0571508
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2-Propen-1-ol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 22 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
10,971
604,872
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
4
13
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Manufacture of flavorings, perfumes; chemical intermediate (HSDB)
Value
1.325
0.17
5.00E-06
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
3-Hydroxycarbofuran
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 23 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
3-Hydroxycarbofuran
25541
16655826
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00006
7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Inhibition of brain cholinesterase in pups - The RfD for
the parent covers the toxicity of the metabolite
Decreased body wt.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.42
Y/N
Y/N
W/L
W/L
Prevalence Magnitude
2 7 Li
HRL Ratio(s)
NC HRL/NCOD R2 90%: 0.191
Notes
Reference Dose; Basis = BMDL10 0.03 mg/kg-d; UF = 500.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
PCBPBS Pesticde Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN
55802) V.1- 1971- Volume(issue)/page/year 3,435,1973
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
3-Hydroxycarbofuran
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 24 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,700
18
0.14
1
66.3
2.2
2.2
66.3
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,539
Amount
Released
n
PWSs/Sites/Sa
mples
1
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
1
0.022
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0
0.4
0.07
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.191
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.07
Year
Maximum
value of
Detects
0
0.062
0.07
0.07
0.07
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide degradate
Value
38
43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
-------
4,4'-Methylenedianiline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 25 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
4,4'-Methylenedianiline
4202
101779
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.08
4.34
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
Critical Effect
ntense liver degenerative lesions, hyperplasia of the
stroma
Liver - fatty liver degeneration, Kidney, Ureter, Bladder -
interstitial nephritis, Blood - normocytic anemia
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.25
1.6
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
560
0.022
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,
7 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 5 week oral study in dogs; JJATDK JAT, Journal of Applied
Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year 11,367,1991
Supplemental Data
Slope factor withdrawn
Vol. 39, Suppl. 7; 1987
IARC, CACART, OEHHA, RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4,4'-Methylenedianiline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 26 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
96,446
168,919
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
2
10
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; corrosion nhibitor; curing agent for polyurethanes (HSDB)
Value
4,950
1.59
1.58E-11
1,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
-------
Acephate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 27 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acephate
31325
30560191
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0012
0.004
0.004
0.03
10
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
1990
Critical Effect
Brain ChE inhibition
Brain and Coverings - other degeneratve changes,
Autonomic Nervous System - sympathomimetic,
Biochemical - Metabolism (Intermediary) - amino acids
(including renal excretion)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.4
0.0087
C
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1988
Liver
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
8.4
4
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 7 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 1.17
CAR HRL/SWC EEC: 0.556
Notes
Reference Dose; Basis = NOAEL 0.12 mg/kg-d; UF = 100.
Reference Dose; Basis = LOEL females = 0.15 mg/kg-d; LOEL males = 0.12 mg/kg-d; Adjusted Basis
Value = LOAEL 0.0004 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; ENVRAL Environmental Research. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1967- Volume(ssue)/page/year 43,342,1987
Supplemental Data
EPA; RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acephate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 28 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
2,462,354
0
20,751
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
35
0
5
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 7.2 ug/L
Ground water chronic: 0.02 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.17
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.556
nsecticide (HSDB)
Value
21.8
-0.85
5.02E-13
818,000
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
Acetaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 29 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetaldehyde
2622
75070
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - changes in motoractivity (specific assay)
Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/DBP ICR MED: 3.15
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issueXpage/year PB234-882; 22-wk guinea pig study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1988
1999
Vol. 36, Suppl. 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
23.3
Y/N
Y/N
ug/L
ug/L
Teratogen list
IARC, EPA, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Acetaldehyde
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 30 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF ICR
# PWSs/Sites
sampled
236
#with Detects
27
% PWSs/Sites
with detects
11.44
Minimum value of
Detects
Maximum
value of
Detects
18.3
Median value of
Detects
T.4
Mean value of
Detects
8.04
Units for Mag
data
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
370,815
14,683,890
n
PWSs/Sites/Sa
mples
8
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
% Samples with
detects
Number of
States
31
38
%
PWSs/Sites/Sam
pies with
detects
37.5
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
1
Non-cancer: 3.15
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
24
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Notes
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
2
90% of
Detects
4
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide; food additive; chemica intermediate (HSDB)
Value
1.498
-0.34
6.68E-05
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Acetamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 31 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetamide
2411
60355
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
o.or
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.5
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
7 9 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART; OEHHA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 32 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
2,754
1,202,667
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
3
7
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; solubilizer; plasticizer; stabilizer (HSDB)
Value
5
-1.26
1.21E-08
2,250,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BF
Notes
BF = biodegrades fast
-------
Acetochlor
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 33 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor
32393
34256821
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
5.45
Units
mg/kg-d
mg*g-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
Critical Effect
Salivation, increased ALT & omithine carbamyl
transferase; increases in triglyceride & decreased blood
glucose levels; histopathological changes in kidneys &
testes
Brain and Coverings - other degenerative changes, Blood -
methemoglobinemia-carboxyhemoglobin, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - dehvdroaenases
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
140
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQ 90% : 179
Notes
Reference Dose
Reference Dose; Basis NOAEL 2 mg*g-d; UF = 100. ICI, Inc., 1988a
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 42-day study in rat; PRKHDK Problemi na Khigienata. Problems in
Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, PI. Slaveikov 11, Sofia, Bulgaria) V.1- 1975-
Volume(issue)/page/year 15,96,1990
Supplemental Data
CACART
Drinking Water Equ valent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetochlor
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 34 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529
Amount
Released
32,591,175
n
PWSs/Sites/Sa
mples
n
PWSs/Sites/Sa
mples
1,872
848
278
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
115
69
#with Detects
0
293
5.02
Number of
States
35
%
PWSs/Sites/Sam
pies with
detects
35.6
30.3
%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
0.026
Non-cancer: 179
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
30.4
Year
1997
Maximum value
of Detects
0.334
0.395
Maximum value
of Detects
21
0.032
0.784
8.49
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.022
95% of Detects
0.002
0.061
90% of Detects
1.5
Units
ug/L
ug/L
Units
ug/L
ug/L
Cancer:
Notes
Pesticide Pilot Mentoring Program (USGS/EPA)
Notes
Drinking water monitoring; http://www.cdph.ca.gov/certlic/
drinkingwater/Pages/Chemicalcontaminants.aspx
Herbicide (HSDB)
Value
4.3
98.5-239
3.03
5.4E-11
233
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast (half-life is for soil)
-------
Acetochlor ESA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 35 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor ethanesulfonic acid (ESA)
79191
187022113
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
1 1
Scores based on parent
HEALTH EFFECTS DATA1 - See Acetochlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
23
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Reduced body weights and body weight gains in both
sexes
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
161
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 205 (NAWQA data for acetochlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR ACETOCHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Acetochlor ESA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 36 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data - FOR ACETOCHLOR - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data - FOR ACETOCHLOR - PARENT
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ACETOCHLOR ESA
POP finished water
FOR ACETOCHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529
Amount
Released
32,591,175
n
PWSs/Sites/Sa
mples
377
n
PWSs/Sites/Sa
mples
1,872
848
278
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
5
#with Detects
0
293
5.020
Number of
States
35
%
PWSs/Sites/Sam
pies with
detects
1.3
%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011
Units
States
States
States
Minimum value of
Detects
0.02
Minimum value of
Detects
0.026
Non-cancer: 205
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
30.4
Year
1997
Maximum value
of Detects
0.02
Maximum value
of Detects
21
0.032
0.784
8.49
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
FOR ACETOCHLOR - PARENT
Median value of
Detects
Median value of
Detects
0.022
95% of Detects
90% of Detects
1.5
Units
ug/L
Units
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USD A); 2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
NAWQA data for acetochlor - parent
Pesticide degradate
Value
Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Acetochlor OA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 37 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor oxani ic acid (OA)
79193
194992444
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
1 1
Scores based on parent
HEALTH EFFECTS DATA1 - See Acetochlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
23
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Reduced body weights and body weight gains in both
sexes
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
161
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 205 (NAWQA data for acetochlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR ACETOCHLOR OA
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Acetochlor OA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 38 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data FOR ACETOCHLOR - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data FOR ACETOCHLOR - PARENT
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
TRI Release - total
Supplemental wate data FOR
ACETOCHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,72, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529
Amount
Released
32,591,175
n
PWSs/Sites/Sa
mples
1,872
848
278
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
293
5.02
Number of
States
35
%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011
Units
States
States
States
Minimum value of
Detects
0.026
Non-cancer: 205
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
30.4
Year
1997
Maximum value
of Detects
21
0.032
0.784
8.49
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
FOR ACETOCHLOR - PARENT
Median value of
Detects
0.022
90% of Detects
1.5
Units
ug/L
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
NAWQA data for acetochlor - parent
Pesticide degradate
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Acrolein
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 39 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acrolein
4581
107028
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
0.0005
0.0005
0.5
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2003
12/1990
Critical Effect
Decreased survival
Hemato.
Liver - liver function tests impaired, Kidney, Ureter,
Bladder - other changes
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1995
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3.5
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
3 7 Li L
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 .03
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.05 mg/kg-d; UF = 100. Parent, et. al, 1S92a
Reference Dose
Reference Dose (IRIS)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week study in rat; VCVGK "Vrednie chemichescie veshestva,
galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year -,385,1994
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Acrolein
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 40 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
1,108
Amount
Released
1
284,480
# PWSs/Sites
sampled
2
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.18
Number of
States
1
16
% PWSs/Sites
with detects
1.3
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.03
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
3.4
Year
2004
2004
Maximum
value of
Detects
2.35
3.4
3.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Aquatic herbicide; rodenticide; industrial chemical (HSDB)
Value
120-180
3
-0.01
1.22E-04
212,000
Units
hours in water
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BF
Notes
pH = 7; BF = biodegradesfast
-------
Alachlor ESA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 41 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Alachlor ethanesulfonic acid (ESA)
71246
142363539
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
157
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased incidence of clinical signs of toxicity in
males and females and decreased body weight gains
in males.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
0.04
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,100
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,,,
93 NL
Scores based on parent HRL Ratio(s)
NC HRL/NAWQA 90% : 4,300 (NAWQA data for
alachlor - parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP - FOR ALACHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data
FOR ALACHLOR - PARENT
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Alachlor ESA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 42 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data - FOR ALACHLOR PARENT
NAWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ALACHLOR ESA
POP finished water
POP finished water
FOR ALACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,166
Amount
Released
n
PWSs/Sites/Sa
mples
79
233
n
PWSs/Sites/Sa
mples
8,112
2,111
568
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
76
#with Detects
3
361
7.9
Number of
States
%
PWSs/Sites/Sam
pies with
detects
3.8
32.6
%
PWSs/Sites/Sam
pies with
detects
0.0003
17.1
0.0008
Units
States
States
States
Minimum value of
Detects
0.50
0.02
Minimum value of
Detects
0.24
0.0125
Non-cancer: 4,300
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
38.2
Year
Maximum
value of
Detects
0.50
1.44
Maximum
value of
Detects
14
10.78
0.015
0.256
3.33
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
4.29
0.06
95% of
Detects
90% of
Detects
11.09
0.55
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USD A); 2001
2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminant
s.aspx
NAWQA data for alachlor - parent
Pesticide degradate
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
AlachlorOA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 43 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Alachlor oxanilic acid (OA)
79196
171262172
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.04
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.4
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
93 Li
Scores based on parent HRL Ratio(s)
CAR HRL/NAWQA 90% : 1 .56 (NAWQA data for
alachlor- parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
FOR ALACHLOR - PARENT
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
AlachlorOA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 44 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data - FOR ALACHLOR PARENT
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ALACHLOR OA
POP finished water
POP finished water
FOR ALACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,166
Amount
Released
n
PWSs/Sites/Sa
mples
137
411
n
PWSs/Sites/Sa
mples
8,112
2,111
568
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
21
#with Detects
3
361
r.9
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.07
5.1
%
PWSs/Sites/Sam
pies with
detects
0.0003
17.1
0.0008
Units
States
States
States
Minimum value of
Detects
0.50
0.121
Minimum value of
Detects
0.24
0.0125
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
38.2
Year
Maximum
value of
Detects
0.50
0.392
Maximum
value of
Detects
14
10.8
0.015
0.256
3.33
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Median value of
Detects
4.29
0.06
95% of
Detects
90% of
Detects
11.09
0.55
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer: 1.56
Notes
Pesticide Data Program (USDA); 2001
2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
NAWQA data for alachlor - parent
Pesticide degradate
Value
Units
ength of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
alpha-Hexachlorocyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 45 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
alpha-Hexachlorocyclohexane
6535
319846
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.008
1.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
9/2003
Critical Effect
Hepatic
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - hepatic microsomal mixed oxidase
(dealkylation, hydroxylation, etc.), Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
catalases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other oxidoreductases
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0006
6.3
2.7
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
56
0.006
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
4 3 Li
HRL Ratio(s)
NC HRL/NAWQA 90% : 949
CAR HRL/NAWQA 90%: 0.102
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Basis NOAEL 0.8 mg/kg-d; UF = 1 00.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
56,137,1991
Supplemental Data
IRIS
EPA; RAIS; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
alpha-Hexachlorocyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 46 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,113
Amount
Released
# PWSs/Sites
sampled
21
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.295
Number of
States
% PWSs/Sites
with detects
0.0004
Units
States
States
States
Minimum value of
Detects
Non-cancer: 949
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.21
Year
Maximum
value of
Detects
0.011
0.059
0.21
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 0.102
Notes
Component of benzene hexachloride (BHC) former insecticide (HSDB)
Value
1.2
641-1,995
3.8
6.70E-06
2
Units
years
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BST
Notes
hydrolysis only, pH = 7; BST = biodegrades sometimes/reca citrant
-------
Anatoxin-a
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 47 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Anatoxin-a
80772
64285069
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Mortality
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3.5
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
9 8 L
Scores based on supplemental data HRL Ratio(s)
NC HRL/Cyano HABs MAX: -0.35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis NOAEL 0.5 mg/kg-d. Astrachan, N.B. and B.G. Archer. 1981.
Simplified monitoring of anatoxin-a by reverse-phase high performance liquid chromatography
and the sub-acute effects of anatoxin-a in rats. In: The Water Environment: Algal Toxins and
Health, W.W. Carmichael, Ed. Plenum Press, New York, NY. p. 437-446. Astrachan, N.B., B.G,
Archer and D.R. Hilbelink. 1980, Evaluation of thesubacutetoxicity and teratogenicity of anatoxin-
a. Toxicon. 18(5-6): 684-688.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Anatoxin-a
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 48 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Prev: UCMR1 Meeting summary; Mag:
CyanoHABs - The Florida Experience
HRL Ratios (HRL/CyanoHABs MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
4
Units
States
States
States
Minimum value of
Detects
Non-cancer: -0.35
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
~10
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Prev: Lake Champlain, NY study; Mag: 2000 Florida study
Cyanobacterial toxin
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Aniline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 49 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aniline
2438
62533
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.007
0.007
2.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
Critical Effect
Blood- effects; Spleen-effects
spleen
Blood - pigmented or nucleated red blood cells, Blood -
methemoglobinemia-carboxyhemoglobin, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - other esterases
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.6
0.0057
0.0057
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1987
spleen
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
49
6
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
98 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Provisional value; 104-week chronic study in rat for aniline hydrochloride. CUT,
1982.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; CIIT.1982; Basis LOAEL 7.2 mg/kg-d; rat; UF = 1,000
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 12 week oral study in rats; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 24(7), 44,1 959
Supplemental Data
from IRIS
Vol. 27, Suppl. 7; 1987
EPA, CACART, OEHHA, RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Aniline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 50 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
1,903
937,263
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
7
20
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemica ; as solvent; synthesis of explosives, rubber accelerators, isocyanates (HSDB)
Value
44.78
0.9
2.02E-06
36000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades Fast
-------
Bensulide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 51 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bensulide
9553
741582
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
271
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Plasma & brain ChE inhibition, decreased body weight
gain
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 6 Li
HRL Ratio(s)
NC HRL/SWC EEC: 0.224
Notes
Reference Dose; Basis = NOAEL 0.5 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C42,1991
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bensulide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 52 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
545,406
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
34
Units
States
States
States
Year
1997
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 158 ug/L
Ground water chronic: 1 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.224
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
Herbicide (HSDB)
Value
9.15E-09
15
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
-------
Benzyl chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 53 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Benzyl chloride
4107
100447
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
26.6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cardiac - other changes, Gastrointestinal - necrotic
changes, Related to Chronic Data - death
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.02
0.17
0.17
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1989
Thyroid
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
62
0.2
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJIND8 JNCI, Journal of the National Cancer Institute.
(Washington, DC) V. 61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year
76,1231,1986; 26 week oral study in rats
Supplemental Data
2B from IARC
Lijinsky, 1986
CACART, EPA, RAIS, OEHHA, IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Benzyl chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 54 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, etal., 2006
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
259
18,750
n
PWSs/Sites/Sa
mples
12
Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0
Number of
States
3
10
%
PWSs/Sites/Sam
pies with
detects
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
Notes
Krasner, etal., 2006. Env. Sci. &Technol., 40(23), pp. 7175-7185.
Cancer:
Chemical intermed ate (NTP)
Value
517.8
2.3
4.11E-04
20
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
-------
Butylated hydroxyanisole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 55 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butylated hydroxyanisole
28160
25013165
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.249
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1959
Critical Effect
Liver - changes in liver weight
Prevalence Magnitude
8 4 NLi
HRL Ratio(s)
NC HRL/NREC NA GW MED: 0.484
CAR HRL/NREC NA GW MED: 146
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AJEBAK Australian Journal of Experimental Biology and
Medical Science. (Adelaide, S.A., Australia) V.1 -64, 1 924-86. Volume(issue);page/year 37,533,1 959
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Vol. 40, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.581
175
Y/N
Y/N
ug/L
ug/L
CACART; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Butylated hydroxyanisole
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 56 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal.,2002
Focazio, etal., 2008
HRL Ratios (HRL/NREC NA GW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
85
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
2
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2.4
% Samples with
detects
3
0.61
Number of
States
%
PWSs/Sites/Sam
pies with
detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.484
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.2
Not detected
0.1
Median value of
Detects
0.2
1.2
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
Cancer: 146
Notes
National Surface Water Reconnaissance; Kolpin, et al., 2002. Env. Sci.
&Technol.,36(6), pp. 1202-1211.
A national reconnaissance for Pharmaceuticals and other organic
wastewater contaminants in the United States ~ II. Untreated drinking
water sources. Focazio, etal., 2008. Sci. Tot. Env., 402(2-3), pp. 201-
216.
Food additive (antoxidant) (HSDB)
Value
38 days
1,390
3.5
1.17E-06
15
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Captan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 57 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Captan
5825
133062
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.13
0.13
0.1
19.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1995
Critical Effect
Decreased pup body weight
Kidney, Ureter, Bladder - other changes in urine
composition, Blood - pigmented or nuceated red blood
cells, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - transaminases
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0024
0.0035
0.0023
3
mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
910
14.6
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/SWC EEC: 84.3
CAR HRL/SWC EEC: 1.35
Notes
Reference Dose; Basis = NOEL 12.5 mg/kg-d; UF = 100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 38(9), 24,1 973
Supplemental Data
CACART; EPA; OEHHA; RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Captan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 58 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
3,992,782
15
2,938
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
39
3
6
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 10.8 ug/L
Ground water chronic: 0 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 84.3
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 1.35
Fungicide (NTP)
Value
862.2
2.8
7.01 E-09
5.1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades Sometimes/Reca citrant. However, hydrolysis half-life s 4.9 hrs - 1 8.8 hrs @ pH 7 and 5, respectively.
-------
Chlorate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 59 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chlorate
24376
14866683
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
5
1.4
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2005
Critical Effect
Thyroid hypertrophy and mineralization
Bone marrow hyperplasia; thyroid folicular hypertrophy
and mineralization
Blood - pigmented or nucleated red blood cells, Blood -
changes in erythrocyte (RBC) count, Nutritional and Gross
Metabolic - weight loss or decreased weight gain
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Not likely to be carcinogenic at
doses that do not alter thyroid
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/DBP ICR 90% : 0.656
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data - NTP Abstract for TR-51 7; 2-year rat study for sodium chlorate
Lowest Observed Adverse Effect Level; 1-year oral rat study fopr sodium chlorate; Journal of
Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466)
V.5(4)- 1984- Volume(issue)/page/year
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 60 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
# PWSs/Sites
sampled
1,713
#with Detects
1,490
% PWSs/Sites
with detects
86.7
Mean value of
Detects
172
Maximum
value of
Detects
2,234
Median value of
Detects
120
90% of
Detects
320
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
7,261,557
n
PWSs/Sites/Sa
mples
116
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
66
Number of
States
16
%
PWSs/Sites/Sam
pies with
detects
56.9
Units
States
States
States
Median of Detects
110
Non-cancer: 0.656
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
1997
2004
2004
Maximum of
Detects
747
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
For sodium chlorate
Units for Mag data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.aspx
Cancer:
Agricultural defol ant or desiccant and in the production of CIO 2 (HSDB).
Value
1,000,000
Units
days
L/kg
unitless
cm3/g
atm-m3/mol
mg/L
Degradation
Code
Notes
For sodium chlorate
-------
Chloromethane (Methyl chloride)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 61 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloromethane (Methyl chloride
2605
74873
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.004
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Mild neurological effects in humans occupationally
exposed to Chloromethane
Cancer Data
EPA Lifetime Cancer Risk, ICT*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.013
D
3
mg/L
(mg/kg-d)-'
(mg/kg-d)"1
1981
2001
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
28
2.69
Y/N
Y/N
mg/L
ug/L
ug/L
2006
developmental
Teratogen
Prevalence Magnitude , „ ,
87 L' L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 2.15
CAR HRL/NCOD R1 90%: 0.207
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CUT, 1981
Vol. 41,Suppl. 7, Vol. 71; 1999
CACART, RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Chloromethane (Methyl chloride)
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 62 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NGOD Round 2 finished water
NIRS finished water
20,246
23,478
248
528
1.22
2.25
0.01
0.00073
550
312
1.9
1.4
13
5
120
29
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasneretal., 2006
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,959
Amount
Released
1,539
1,733,197
n
PWSs/Sites/Sa
mples
11,984
12
356
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
247
1
8.99
Number of
States
10
26
%
PWSs/Sites/Sam
pies with
detects
2.1
8
0.007
Units
States
States
States
Minimum value of
Detects
0.25
Non-cancer: 2.15
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
21
Year
2004
2004
Maximum
value of
Detects
46
0.04
0.1
0.58
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.7
ND
90% of
Detects
2
Units for Mag
data
ug/L
ug/L
Cancer: 0.207
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Krasner, etal., 2006. Env. Sci. &Technol., 40(23), pp. 7175-7185.
Foaming agent; in organic synthes s (HSDB); naturally-occurring gas
Value
15
14
0.91
8.82E-03
5320
43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = Biodegrades Slowly
-------
Clethodim
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 63 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Clethodim
76719
110429624
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
0.01
1,360
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Increased liver weights increased liver enzymes and
iver histopathology
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
70
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 6 Li
HRL Ratio(s)
NC HRL/SWC EEC: 9.21
Notes
Reference Dose; Basis = NOEL 1 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Oral study in rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C272,1991
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Clethodim
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 64 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
670,721
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
39
Units
States
States
States
Year
1997
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data:
OPP Estimated Environmental Concentration
Surface water chronic: 7.6 ug/L
Ground water chronic: 0.49 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 9.21
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
Herbicide; pesticide degradate
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Cobalt
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 65 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cobalt
18870
7440484
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.01
0.0014
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2004
2000
Critical Effect
Blood-increased hemoglobin, polycythemia;
respiratory-effects on lung function
Heart
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,,, _
4 8 NL'
HRL Ratio(s)
NCHRL/NIRS90%:6.67
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; 'multiple studies as cited in ATSDR, 1992; UF = 30; human study; RIVM; Basis
LOAEL = 0.04 mg/kg-d
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Vol. 52; 1991; NB: Evaluated as a group; Cancer classifications were used for screening, but no related
quantitative cancer risk data were identified for potency scoring.
IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cobalt
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 66 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
3
0.303
6.4
10.6
9.7
10.5
10.6
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,297
Amount
Released
1,272
786,491
# PWSs/Sites
sampled
782
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
23.7
Number of
States
17
38
% PWSs/Sites
with detects
0.007
Units
States
States
States
Minimum value of
Detects
Non-cancer: 6.67
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
684
Year
2004
2004
Maximum
value of
Detects
0.22
3.91
53.2
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for cobaltous chloride: Formerly in medicines; as germicide (HSDB); naturally-occurring
Value
534,200
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BST
Notes
assumed persistent; All use and env. fate data are for cobaltous chloride; BST = biodegrades sometimes/reca citrant
-------
Cumene hydroperoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 67 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cumene hydroperoxide
2927
80159
Attribute Scores
Potency Severity
4 9
Prevalence Magnitude
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
32.7
382
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Mortality
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
76.4
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AIHAAP American Industrial Hygiene Association Journal.
(AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issueXpage/year
19,205,1958; 7 week oral study in rats
Supplemental Data
Oral study in rats
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cumene hydroperoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 68 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
96
443,772
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
15
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (HSDB)
Value
2.16
4.71 E-08
13,900
25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation; PBT
-------
Cylindrospermopsin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 69 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cylindrospermopsin
81115
143545908
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00003
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg*g-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Increased kidney weight
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.21
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „
5 10 L'
Scores based on supplemental data HRL Ratio(s)
c^notoxTsuryr00" *"** °" ""** NC HRL/CyanoHABs MAX: -0.0021
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis LOAEL 60 ug/kg-d; NOAEL 3 ug/kg-d. Humpage, A.R. and I.R.
Falconer. 2003. Oral toxicity of the cyanobacterial toxin Cylindrospermopsin in male Swiss albino
mice: Determination of no observed adverse effect level for deriving a drinking water guideline
value. Environ. Toxicol. 18(2):94-103.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cylindrospermopsin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 70 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CyanoHABs - The Florida Experience
UCMR 1 Meeting summary
HRL Ratios (HRL/CyanoHABs MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
Not Available
Not Available
Units
States
States
States
Minimum value of
Detects
Non-cancer: -0.0021
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
-100
90
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
2000 Florida study
Florida survey
Cyanobacterial toxin
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Dicrotophos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 71 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dicrotophos
6098
141662
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00007
0.0001
0.0001
11
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Decreased plasma, RBC & brain ChE activity
Decreased body weight
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
Suggestive
evidence
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.49
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 2.45
Notes
Reference Dose; Basis = LOAEL 0.02 mg/kg-d; UF = 300.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa,
Ont, Canada) Volume(issue)/page/year 6,196,1973
OPP; no quantif cation
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dicrotophos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 72 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
359,726
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
13
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
Maximum
value of
Detects
0
0
Surface water chronic: 0.2 ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
0
0
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA); 2002
2002
Ground water chronic: 0.005 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 2.45
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
nsecticide (HSDB)
Value
366.2
-0.49
5.05E-11
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = Biodegrades Slowly
-------
Dimethipin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 73 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dimethipin
36818
55290647
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0218
0.02
0.02
0.02
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1999
Critical Effect
Kidney, lungs, duodenum, liver, glandular stomach,
heart, aortic artery & testes toxicity. Decreased body
weight gain.
ncreased absolute and relative liver weight
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
153
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
8 5 Li
HRL Ratio(s)
NC HRL/GWC EEC: 1.55
Notes
Reference Dose; Basis = NOEL 2.1 8 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethipin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 74 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
282,458
0
250
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
14
0
1
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 7.3 ug/L
Ground water chronic: 99 ug/L
HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.55
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
Herbicide; plant growth regulator (HSDB)
Value
27.41
-0.17
2.30E-11
4,600
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = biodegrades slowly with acclimation; PBT
-------
Dimethoate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 75 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dimethoate
2413
60515
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0022
0.0002
0.0002
0.002
3
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2007
1988
1996
Critical Effect
Brain cholinesterase inhibition
Brain cholinesterase nhibition
Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
2006
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
15.4
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude , „ ,
10 7 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 0.655
Notes
Reference Dose; OPP RED
Reference Dose; Basis NOEL 0.05 mg/kg-d; UF = 100. American Cyanamid Co., 1986a
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level - 52-week study in rat; BJIMAG British Journal of Industrial
Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
Volume(issue)/page/year21,52,1964
Supplemental Data
OPP
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dimethoate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 76 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
CAL DHS
STORE!
Amount
Released
1,896,947
2,615
31,480
n
PWSs/Sites/Sa
mples
n
PWSs/Sites/Sa
mples
7,238
890
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
4
#with Detects
0
14
Number of
States
44
2
4
%
PWSs/Sites/Sam
pies with
detects
1.3
%
PWSs/Sites/Sam
pies with
detects
0
1.57
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
0.055
Year
1997
2004
2004
Maximum
value of
Detects
0.022
Maximum
value of
Detects
0.21
Surface water chronic: 23.5 ug/L
Non-cancer: 0.655
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.148
95% of
Detects
90% of
Detects
0.198
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.044 ug/L
Cancer:
Pesticide (NTP)
Value
8
5.2-36
0.78
2.43E-10
23,800
36
Units
weeks
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = biodegrades slowly with acclimation
-------
Disulfoton
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 77 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Disulfoton
6423
298044
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00013
0.00004
0.0001
0.00004
0.00006
0.0003
0.06
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2002
1986
2006
08/1995
1991
Critical Effect
Plasma, RBC, brain & corneal ChE inhibition
Brain and Coverings - other degenerative changes, Blood -
other changes, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - true cholinesterase
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
E
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.0035
0.91
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NCHRL/NAWQA90%: 1.1
Notes
Reference Dose; Basis = NOAEL 0.013 mgrtsg-d; UF = 100.
Reference Dose; Basis = LOAEL 0.04 mg/kg-d; UF = 1 ,000.
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology. (Academic Press,
Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
Volume(issue)/page/year35,101,1997
Supplemental Data, ITER
Cancer classifications were used for screening, but no related quantitative cancer risk data were identified for
potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Disulfoton
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 78 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
Amount
Released
1,196,066
n
PWSs/Sites/Sa
mples
17
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
0.24
Number of
States
33
%
PWSs/Sites/Sam
pies with
detects
0
0
0.002
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.1
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
3.81
Year
1997
Maximum value
of Detects
Not Detected
Not Detected
0.02
0.826
3.81
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of Detects
Not Detected
Not Detected
Units for Mag
data
Cancer:
Notes
Pesticide Pilot Mentoring Program (USGS/EPA); 2002
2002
nsecticide (HSDB)
Value
7-41
684-14,013
4.02
2.20E-06
16.3
17
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades Slowly
-------
Diuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 79 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Diuron
6583
330541
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.002
0.003
0.002
1.75
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2006
Critical Effect
Hemolytic anemia & compensatory hematopotesis
(decreased erythrocyte count, hemoglobin level, etc).
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Liver - changes in liver weight, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases
Cancer Data
EPA Lifetime Cancer Risk, 104
EPA OPP Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0191
Known/Likely
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
2003
2003
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
21
1.83
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Teratogen
Prevalence Magnitude
4 7 NL!
HRL Ratio(s)
NCHRL/UCMR90%: 10
CAR HRL/UCMR 90%: 0.871
Notes
Reference Dose; du Pont, 1364a; Basis = LOAEL 1 .0 mg/kg-d; UF = 300.
Reference Dose; Basis NOEL 0.625 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year36,76,1990
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
EPA, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diuron
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 80 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
298
1
0.34
2.1
2.1
2.1
2.1
2.1
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,552
Amount
Released
4,370,448
10
798
n
PWSs/Sites/Sa
mples
270
319
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
117
13
7.00
Number of
States
39
2
5
%
PWSs/Sites/Sam
pies with
detects
0.4
37.5
5.8
0.0004
Units
States
States
States
Minimum value of
Detects
0.058
Non-cancer: 10
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
23.3
Year
1997
2004
2004
Maximum
value of
Detects
0.058
0.54
0.079
0.09
0.915
8.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
0.319
0.079
Units
ug/L
ug/L
ug/L
Cancer: 0.871
Notes
Pesticide Data Program (USDA); 2002
Herbicide (HSDB
Value
224-879
2.68
5.8E-10
36.4
15
Units
months
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BST
Notes
BST = biodegrades sometimes/recalcitrant
-------
Equilenin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 81 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Equilenin
81750
517099
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
9 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormonal response in post-menopausal
women
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
L?-L
HRL Ratio(s)
NC HRL/Kolpin MAX: 1.26
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Equilenin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 82 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
2.8
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.26
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.278
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.14
90% of
Detects
Units for Mag
data
ug/L
Notes
National Surfac
Sci.&Technol
e Water Reconnaissance; Kolpin, etal., 2002. Env.
36(6), pp. 1202-1211.
Cancer:
Pharmaceutical, hormone
Value
3.93
1.52
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Equilin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 83 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Equilin
81748
474862
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
8 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormonal response in post-menopausal
women
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
L?-L
HRL Ratio(s)
NC HRL/Kolpin MAX: 2.38
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Equilin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 84 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
ro
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
1.4
Units
States
States
States
Minimum value of
Detects
Non-cancer: 2.38
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.147
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.147
90% of
Detects
Units for Mag
data
ug/L
Notes
National Surfac
Sci. & Technol
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.
Cancer:
Pharmaceutical, hormone
Value
38
3.35
1.41
13
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Erythromycin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 85 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Erythromycin
75632
114078
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0007
66.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Inhibition of beneficial gastrointestinal bacteria
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
4.9
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 4
HRL Ratio(s)
NC HRL/NREC MAX: 2.88
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Erythromycin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 86 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Focazio, etal., 2008
HRL Ratios (HRL/NREC MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
104
90
Amount
Released
n
PWSs/Sites/Sa
mples
22
0
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
21.5
0.0
Number of
States
%
PWSs/Sites/Sam
pies with
detects
Not detected
Units
States
States
States
Minimum value of
Detects
Non-cancer: 2.88
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.7
Not detected
Year
Maximum
value of
Detects
0.3
0.1
Not detected
Not detected
Not detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
90% of
Detects
Units for Mag
data
ug/L
Notes
Drinking water monitoring; Focazio, etal., 2008. Sci.Tot. Env. 402(2-3),
pp. 201-216.
Cancer:
Pharmaceutica , antibiotic
Value
180
3.06
5.20E-29
6
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Estradiol (17-beta estradiol)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 87 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estradiol (17-beta estradiol)
2130
50282
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormona response in post-menopausal women
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
39
1
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.35
0.0009
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude ,
10 5 L
HRL Ratio(s)
NC HRL/Kolpin MAX: 1.75
CAR HRL/Kolpin MAX: 0.0045
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
IARC, CACART, OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Estradiol (17-beta estradiol)
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 88 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
85
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.0
10.6
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer: 1.75
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Not detected
0.0064
0.2
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not detected
0.16
90% of
Detects
Not detected
Units for Mag No(es
data
ug/L
ug/L
ug/L
Cancer: 0.0045
Finished Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
National Surface Water Reconnaissance; Kolpin, et al., 2002. Env.
Sci.&Techno ., 36(6), pp. 1202-1211.
Pharmaceutical, hormone
Value
38
4.01
6.40E-11
3.6
11
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Estriol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 89 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estriol
75525
50271
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
10 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormonal response in post-menopausal
women
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/Kolpin MAX: 6.86
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Estriol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 90 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.0
0.0
21.4
Units
States
States
States
Minimum value of
Detects
Not detected
Not detected
Non-cancer: 6.86
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Not detected
Not detected
0.051
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not detected
Not detected
0.019
90% of
Detects
Not detected
Not detected
Units for Mag
data
ug/L
ug/L
ug/L
Cancer:
Notes
Finished Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
National Surfac
Sci. & Techno .
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.
Pharmaceutica , hormone
Value
38
2.45
1.33E-12
441
17
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Estrone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 91 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estrone
2210
53167
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Estrogenic hormonal response in post-menopausal
women
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
9 3 Li
HRL Ratio(s)
NC HRL/Swartz MAX: 2.92
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Estrone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 92 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Boyd, etal.,2003
Snyder, 2008
Kolpin.etal., 2002
Swartz, etal.,2006
HRL Ratios (HRL/Swartz MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
7.1
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer: 2.92
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Not detected
0.002
0.112
0.12
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not detected
0.027
90% of
Detects
Not detected
Units for Mag No(es
data
Finished Drinking Water; Boyd, etal, 2003. Sci. Tot. Env. 311(1-3): pp.
135-149.
ug/L
ug/L
ug/L
Cancer:
Raw Drinking Water; Snyder, et al, 2008. Removal of Endocrine
Disrupters and Pharmaceuticals during Water Treatment. In: Fate of
Pharmaceuticals in the Environmental and in Water Treatment Systems.
National Surfac
Sci. & Technol
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.
Ambient Water (SW/GW); Swartz, et al., 2006. Env. Sci. & Technol.
40(16): pp. 4894-4902.
Pharmaceutical, hormone
Value
38
3.13
3.80E-10
30
13
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Ethinyl Estradiol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 93 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethinyl Estradiol (17-alpha ethynyl estradiol)
2327
57636
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
0.015
0.0005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1981
Critical Effect
Hematalogical effects
Increased serum levels of alanine aminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GGT).
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.28
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 4 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.337
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, etal., 1981 as cited in Maier and Hermann, 2001.
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethinyl Estradiol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 94 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.0
0.0
5.7
Units
States
States
States
Minimum value of
Detects (ug/L)
Not detected
Not detected
Non-cancer: 0.337
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects (ug/L)
Not detected
Not detected
0.273
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects (ug/L)
Not detected
Not detected
0.094
90% of
Detects (ug/L)
Not detected
Not detected
Units for Mag
data
ug/L
ug/L
ug/L
Cancer:
Notes
Finished Drinking Water; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Response to Comment on National Surface Water Reconnaissance
Kolpin et al., 2002: Env. Sci. & Technol., 36(18), pp. 4007-4008.
Pharmaceutical, hormone
Value
60
3.67
7.94E-12
11.3
9
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Ethoprop
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 95 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethoprop
22682
13194484
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
0.0004
33
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Plasma ChE inhibition, Q1* 0.0281 (mg/kg-day)-1 -
Likely.
Behavioral - changes in motor activity (specific assay),
Behavioral - muscle contraction or spasticity
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.12
0.0281
Likely
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.7
1.25
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,,, _
7 3 NL'
HRL Ratio(s)
NC HRL/NAWQA 90%: 7.29
CAR HRL/NAWQA 90%: 13
Notes
Reference Dose; Basis = NOAEL 0.01 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
HBPTO Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year 1 ,693,2001
OPP RED and Ethoprop pesticide tolerances: 73 FR 53725, Spetember 17, 2008
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethoprop
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 96 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
Amount
Released
1,010,807
0
77,786
n
PWSs/Sites/Sa
mples
84
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
1.18
Number of
States
28
0
4
%
PWSs/Sites/Sam
pies with
detects
0
0
0.002
Units
States
States
States
Minimum value of
Detects
Non-cancer: 7.29
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.95
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
0.011
0.096
0.8
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer: 13
Notes
Pesticide Pilot Mentoring Program (USGS/EPA); 2001
2001
nsecticide (HSDB)
Value
75-133
70-120
3.59
1.70E-07
750
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
hydrolysis only: BST = biodegrades sometimes/recalcitrant
-------
Ethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 97 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene glycol
4599
107211
Attribute Scores
Potency Severity
3 9
Prevalence Magnitude
10 10
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2
2
2
0.8
0.05
600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2006
2007
2000
Critical Effect
Kidney toxicity. Increased mortality, neutrophil count,
kidney hemoglobin & hematocrit, chronic nephritis
ncreased total malformations and incidence of extra rib 14
in developmental study
Kidney
Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in tubules (including acute renal failure, acute tubular
necrosis), Related to Chronic Data - death
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
14,000
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Teratogen
3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; DePass et al., 1986a; UF = 100; Rat; Basis NOAEL = 200 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Gaunt etal., 1974; UF = 1,000; Rat
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2 year oral study in rate; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year3,229,1965
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 98 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
576,990
10,076,483
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
31
49
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Antifreeze; cancelled pesticide; synthetic chemical used in textile manufacture (NTP)
Value
1
-1.36
6.00E-08
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
Ethylene Oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 99 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene Oxide
2635
75218
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
1.02
0.31
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
1994
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.113
Y/N
Y/N
ug/L
ug/L
Teratogen; Developmental
Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
HEAST
CACART; RAIS; OEHHA; EPA; IARC
UMD; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethylene Oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 100 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
4,761
374,110
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
4
38
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fumigant (NTP); gas
Value
1.435
-0.3
1.48E-04
1,000,000
43
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BS
Notes
PBT; BS = biodegrades slowly
-------
Ethylene thiourea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 101 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene thiourea
3836
96457
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002
0.00008
0.00008
0.00008
0.004
1.34
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
2006
1993
Critical Effect
Thyroid toxicity
ncreased incidence of thyroid hyperplasia
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.006
0.06
0.045
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1988
2001
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.003
1.4
0.06
Y/N
Y/N
mg/L
W/L
W/L
2006
Teratogen; Developmental
Prevalence Magnitude
4 1 NLi
HRL Ratio(s)
NC HRL/GWC EEC: 6.67
CAR HRL/GWC EEC: 0.286
Notes
Reference Dose
Reference Dose; Basis LOAEL 0.25 mg/kg-d. Graham etal., 1975
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 8-week study in rat; JAFCAU Journal of Agricultural and Food
Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn.,
Washington, DC 20037) V.1- 1953- Volume(issue)/page/vear 21,324,1973
Supplemental Data
OPP
OPP
EPA; RAIS; OEHHA; IARC; CACART
UMD; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ethylene thiourea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 102 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
5
299
Units
Ibs/yr
Ibs/yr
Ibsfyr
Number of
States
1
4
Units
States
States
States
Year
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 0.1 ug/L
Ground water chronic: 0.21 ug/L
HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 6.67
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.286
Pesticide (NTP)
Accelerator; industrial intermediate (HSDB)
Value
15
6.5
-0.66
3.40E-07
20,000
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
(at 30 C)
-------
Fenamiphos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 103 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Fenamiphos
27401
22224926
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
0.00025
0.0001
0.00025
0.0008
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
2006
1997
Critical Effect
Plasma ChE inhibition.
Cholinesterase inhibit on
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
E
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1988
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.0035
0.7
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 0.051
Notes
Reference Dose; Basis = NOAEL 0.01 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 0.025 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring. OPP changed cancer classification from D to E.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Fenamiphos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 104 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
726,675
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
14
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 13.7 ug/L
Non-cancer: 0.051
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic: 0.47 ug/L
Cancer:
nsecticide (HSDB)
Value
225.1
3.23
1.21E-09
329
12
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BSA
Notes
BSA = biodegrades slowly with acclimation; PBT
-------
Formaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 105 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Formaldehyde
2119
50000
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.2
0.2
0.2
12.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
2006
1999
Critical Effect
Reduced weight gain, histopathology in rats.
Decreased absolute heart, liver, testes & kidney
weights. Increased relative brain, testes weights.
Gastro.
Liver - other changes, Blood - changes in spleen
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
B1
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1993
1995
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
7
1,400
Y/N
Y/N
ug/L
ug/L
ug/L
2006
Teratogen
Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/DBP ICR MED: 184
Notes
Reference Dose
Reference Dose; Basis = NOAEL 15 mg/kg-d; UF = 100. Til etal., 1989
Reference Dose
Reference Dose
Minimal Risk Level; Basis = NOAEL 15 mg/kg-d; ATSDR MRL-int = 0.3 mg/kg-d (Til etal., 1989).
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Bandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,339,1994
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
CACART; EPA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Formaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 106 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR
# PWSs/Sites
sampled
227
#with Detects
126
% PWSs/Sites
with detects
55.5
Minimum value of
Detects
5
Maximum
value of
Detects
30.6
Median value of
Detects
7.6
99% of
Detects
29.7
Units for Mag
data
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
326,298
26,992,234
Units
Ibs/yr
Ibs/yr
Ibs/yr
Number of
States
31
46
Units
States
States
States
Non-cancer: 184
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Notes
ug/L
ug/L
ug/L
ug/L
ug/L
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Cancer:
Naturally-occurring fungicide (NTP); Disinfection by-Product; gas
Value
1
0.35
3.38E-07
400,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades Fast with Acclimation
-------
Germanium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 107 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Germanium
18876
7440564
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.318
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.744
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
4 10 Li
HRL Ratio(s)
NC HRL/NIRS 90% : 0.003
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJMDAT Japanese Journal of Medicine. (Nankodo Co.,
Ltd., POBS272, Tokyo International 100-31, Japan) V.1-30, 1962-1991. For publisher information,
see IEDIEP. Volume(issue)/page;year 30,67,1991. EPA believes the RTECS LOAEL may be
incorrectly cited (should be 3.18 not 0.318). Both values suggest listing germanium.
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Germanium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 108 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
4
0.40
2B
230
220
220
230
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.003
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for germanium diox de: Phosphors, transistors and diodes; electroplating (HSDB); naturally-occurr ng
Value
4,470
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BST
Notes
assumed persistent; All use and env. fate data are for germanium dioxide; BST = biodegrades sometimes/reca citrant
-------
Halon 1011 (bromochloromethane)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 109 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Halon 1011 (bromochloromethane)
2613
74975
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased liver-to-body weight ratio. Cloudy swelling
and vacuolization of hepatocytes.
Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 7
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.5
70
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For care nogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Halon 1011 (bromochloromethane)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 110 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NGOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,881
22,974
65
106
0.5
0.461
0.05
0.0023
210
33.4
1
1
10
6
210
27.9
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasner, etal., 2006
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1/2, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,238
^Samples
Amount
Released
n
PWSs/Sites/Sa
mples
7
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.165
% Samples with
detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.1
0.0
0.01
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer: 7
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.45
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not detected
0.2
Median value of
Detects
0.422
90% of
Detects
0.45
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
Not detected
99% of
Detects
Not detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Krasner, etal., 2006. Env. Sci. &Technol. 40 (23): pp. 7175-7185.
Fire extinguishing fluid; chemical intermediate (HSDB)
Value
15 days
23.7
1.41
0.00146
16,700
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
HCFC-22
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 111 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
HCFC-22
2654
75456
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
13.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1983
Critical Effect
Brain and Coverings - other degenerative changes,
Blood - changes in other cell count (unspecified),
Nutritional and Gross Metabolic - weight loss or
decreased weight gain
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
31.5
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/page/year 48(8),69,1983
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
HCFC-22
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 112 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
2,972
7,075,769
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
35
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Refrigerant; low-temperature solvent; fluorocarbon resins, especially tetrafluoroethylene polymers (HSDB); gas
Value
15
35.04
1.08
4.07E-02
2,770
43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
-------
Hexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 113 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Hexane
4858
110543
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.06
1,429
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
Critical Effect
Decreased body weight gain
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
420
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
10 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis LOAEL = 570 mg/kg-d, UF = 10,000, oral rat study. Health and
Environmental Effects Document for n-Hexane, ECAO-CIN-Q076, Environmental Criteria and
Assessment Office, Final Draft, September 1989.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TIHEEC Toxicology and Industrial Health. (Princeton Scientific
Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year 1(3), 67,1985
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 114 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
14,489
39,844,882
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
38
53
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Naturally-occurring; solvent (NTP)
Value
149
3.9
1.8
9.5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = biodegrades fast with acclimation
-------
Hydrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 115 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Hydrazine
6460
302012
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.001
3
3
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.01
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART; EPA; IARC; OEHHA; RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hydrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 116 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
5
165,485
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
16
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; rocket propellant; oxygen/chlorine scavenger (HSDB)
Value
14.3
-2.07
1.44E-08
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
Mestranol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 117 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Mestranol
2581
72333
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL (for ethinyl estradiol)
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
0.015
0.00083
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1981
Critical Effect
Hematalogical effects
Increased serum levels of alanineaminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GOT).
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.28
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
94 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.688
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, et al., 1981 as cited in Maier and Hermann, 2001 .
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Mestranol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 118 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Mestranol
2581
72333
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL (for ethinyl estradiol)
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
0.015
0.00083
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1981
Critical Effect
Hematalogical effects
Increased serum levels of alanineaminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GOT).
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.28
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
94 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.688
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, et al., 1981 as cited in Maier and Hermann, 2001 .
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Mestranol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 119 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin.etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
4.3
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.688
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.407
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.017
90% of
Detects
Units for Mag
data
ug/L
Notes
Response to Comment on National Surface Water Reconnaissance
Kolpin et al., 2002: Env. Sci. & Technol, 36(18), pp. 4007-4008.
Cancer:
Metabolite of ethinyl estradiol
Value
60
4.68
Practically
insoluble
9
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Methamidophos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 120 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
965,584
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
39
Units
States
States
States
Year
1997
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 6.9 ug/L
Ground water chronic: 3.8 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.304
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
nsecticide (HSDB)
Value
3.848
-0.8
8.70E-10
1000000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = Biodegrades Slowly
-------
Methanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 121 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methanol
2508
67561
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
0.5
3.13
5,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
ncreased SAP & SGPT& liver weight, decreased brain
weight
Liver - other changes
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3,500
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude , „ ,
10 10 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. EPA, 1986; Basis = NOEL 500 mg(kg-d; UF = 1,000; Rat
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 200 day oral study in rats; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,89,1994
Supplemental Data
Rats; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,87,1984
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 122 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
10,966,234
201,697,278
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
41
52
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; gasoline additive (HSDB); anti-freeze
Value
1
-0.77
4.56E-06
1000000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades Fast
-------
Methyl bromide (Bromomethane)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 123 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methyl bromide (Bromomethane
2601
74839
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0014
0.001
0.0014
0.003
1
29.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
2006
9/1992
1966
Critical Effect
Epithelial hyperplasia in theforestomach
Gastro
Kidney, Ureter, Bladder - other changes in urine
composition, Skin and Appendages - hair, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1989
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.05
9.8
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Developmental
Prevalence Magnitude , „
67 L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.891
Notes
Reference Dose
Reference Dose; Basis = NOAEL 1 .4 mg/kg-day; UF = 1 ,000; Rat. Danse et al.r 1984
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; FCTOD7 Food and Chemical Toxicology.
(Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year28,109,1990
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl bromide (Bromomethane)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 124 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
20,198
23,328
155
175
0.77
0.75
0.07
0.09
43
38.1
1
1.6
11
8.1
34
27.2
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,317
Amount
Released
32,803,943
200
533,748
# PWSs/Sites
sampled
3
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.069
Number of
States
29
3
17
% PWSs/Sites
with detects
0.04
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.891
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.5
Year
1997
2004
2004
Maximum
value of
Detects
0.1
0.5
0.5
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled fumigant (NTP); gas
Value
20-26.7
9-22
1.19
7.34E-03
13,400
42
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BS
Notes
hydrolysis only; BS = biodegrades slowly
-------
Methyl tert-butyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 125 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methyl tert-butyl ether
11918
1634044
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
0.01
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
8/1996
1991
Critical Effect
Hepatic: Decreased blood urea nitrogen levels.
Kidney, Ureter, Bladder - changes in bladder weight, Blood
- changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - changes in
calcium
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0018
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
2,100
19.4
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „
58 L'
HRL Ratio(s)
NC HRL/UCMR 90%: 58.3
CAR HRL/UCMR 90%: 0.539
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis NOAEL 100 mg/kg-d
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in rat; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 9(5), 525, 1990
Supplemental Data
OEHHA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl tert-butyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 126 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,617
17
0.47
5
49
9.2
36
49
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,328
Amount
Released
40,177
2,040,906
# PWSs/Sites
sampled
424
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
9.8
Number of
States
17
42
% PWSs/Sites
with detects
0.01
Units
States
States
States
Minimum value of
Detects
Non-cancer: 58.3
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
2,300
Year
2004
2004
Maximum
value of
Detects
0.3
7.85
1,800
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 0.539
Notes
Octane booster in gasoline; manufacture of isobutene; extraction solvent (HSDB)
Value
15
6
0.94
5.87E-04
51,000
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
-------
Metolachlor
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 127 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor
35270
51218452
Attribute Scores
Potency Severity
4 3
Prevalence Magnitude
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.15
0.1
0.15
25
1,150
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
1988
2006
Critical Effect
Decreased body weight gain
Decreased body weight gain
Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - phosphatases
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1988
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3.5
700
Y/N
Y/N
mg/L
ug/L
ug/L
2006
3-model Categorical Prediction
NL?
HRL Ratio(s)
NC HRL/NCOD R2 90%: 321
Notes
Reference Dose; Basis NOAEL = 9.7 mg/kg-d; UF = 100. OPP RED.
Reference Dose; Basis = NOEL 15 mg/kg-d; UF = 100. Ciba-Geigy, 1983
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 14,103,1989
Supplemental Data
NNGADV Nippon Noyaku Gakka shi. Journal of the Pesticide Science Society of Japan. (Nippon
Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
Volume(issue)/page/year 14,103,1989
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 ~6 cancer risk was used.
-------
Metolachlor
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 128 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
13,007
116
0.89
0.01
13.8
0.57
2.18
7.1
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
PPMP ambient water
PPMP finished water
CAL DHS
STORE!
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,165
Amount
Released
67,336,211
n
PWSs/Sites/Sa
mples
203
582
n
PWSs/Sites/Sa
mples
7,345
2,082
1,817
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
102
233
288
198
#with Detects
15
676
25.4
8.76
1.23
Number of
States
48
%
PWSs/Sites/Sam
pies with
detects
50.2
40
89.2
86.8
%
PWSs/Sites/Sam
pies with
detects
0.2
32.5
0.0002
Units
States
States
States
Minimum value of
Detects
0.01
0.005
Minimum value of
Detects
0.05
0.00867
Non-cancer: 321
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
77.6
Year
1997
Maximum
value of
Detects
0.079
0.226
3.32
0.661
Maximum
value of
Detects
0.7
86
0.025
0.12
0.125
0.58
6.71
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.06
0.19
95% of
Detects
0.033
0.336
90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2001
2002
Pesticide Pilot Mentoring Program (USGS/EPA)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
47;78
22-310
3.13
9.00E-09
530
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
aerobic;anaerobic; BSA = biodegrades slow with acclimaton
-------
Metolachlor ESA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 129 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor ethanesulfonic acid (ESA)
79218
171118095
Attribute Scores
Potency Severity
2 1
Prevalence Magnitude
6 6
Scores based on parent
HEALTH EFFECTS DATA1 - See Metolachlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
21000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
No biologically significant effects
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
>7,000
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : >3,210 (NAWQA data for metolachlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR METOLACHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Metolachlor ESA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 130 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value
of Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag No(es
data
Finished Water Occurrence Data - FOR METOLACHLOR PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
13,007
116
0.89
0.01
13.8
0.57
2.18
7.1
Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
FOR METOLACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NCOD R290%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
83
318
n
PWSs/Sites/Sa
mples
7,345
2,082
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
19
198
#with Detects
15
676
Number of States
%
PWSs/Sites/Samp
les with detects
22.9
51.9
%
PWSs/Sites/Samp
les with detects
0.2
32.5
Units
States
States
States
Minimum value
of Detects
0.50
0.02
Minimum value
of Detects
0.05
0.00867
Non-cancer: >3,210
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
2.21
2.24
Maximum
value of
Detects
0.7
86
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.06
0.19
95% of
Detects
90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2001 - FOR METOLACHLOR ESA
2002 - FOR METOLACHLOR ESA
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.as
px
NCOD data for metolachlor - parent
Pesticide degradate
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation Code
Notes
-------
Metolachlor OA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 131 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor oxani ic acid (OA)
79220
152019733
Attribute Scores
Potency Severity
2 1
Prevalence Magnitude
6 6
Scores based on parent
HEALTH EFFECTS DATA1 - See Metolachlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
No biologically significant effects
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7,000
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 3,210 (NAWQA data for metolachlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR METOLACHLOR OA
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Metolachlor OA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 132 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag No(es
data
Finished Water Occurrence Data - FOR METOLACHLOR PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
13,007
116
0.89
0.01
13.8
0.57
2.18
7.1
Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
FOR METOLACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NCOD R290%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KQC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
138
404
n
PWSs/Sites/Sa
mples
7,345
2,082
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
14
152
#with Detects
15
676
Number of
States
%
PWSs/Sites/Sam
pies with
detects
10.1
37.6
%
PWSs/Sites/Sam
pies with
detects
0.2
32.47
Units
States
States
States
Minimum value of
Detects
0.50
0.02
Minimum value of
Detects
0.05
0.00867
Non-cancer: 3,210
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
4.42
1.41
Maximum
value of
Detects
0.7
86
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.06
0.19
95% of
Detects
90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2001 - FOR METOLACHLOR OA
2002 - FOR METOLACHLOR OA
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.
aspx
NCOD data for metolachlor - parent
Pesticide degradate
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Microcystin-LR
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 133 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Microcystin-LR
76859
101043372
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.000003
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Liver effects
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.021
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 4
Scores based on supplemental data HRL Ratio(s)
NC HRL/AWWARF Typical Range MAX: 0.21
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis NOAEL 3 ug/kg-d. Ueno, Y., Y. Makita, S. Nagata et al. 1 999.
No chronic oral toxicity of a low-dose of microcystin-LR, a cyanobacterial hepatoxin, in female
Balb/C mice. Environ. Toxicol. 14(1):45-55.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Microcystin-LR
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 134 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
US and Canadian drinking water (bloom
area, source, finished water)
US and Canadian drinking water (bloom
area, source, finished water)
HRL Ratios (HRL/AWWARF Typical Range
MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
677
677
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
542
542
Number of
States
%
PWSs/Sites/Sam
pies with
detects
80
80
Units
States
States
States
Minimum value of
Detects
0.002
Non-cancer: 0.21
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.1
1,200
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Maximum of typical range of detects (AWWARF, Carmichael)
Maximum and m numum of detects (AWWARF, Carmichael)
Cyanobacterial toxin
Value
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Molinate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 135 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Molinate
12912
2212671
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.002
0.002
13.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1988
Critical Effect
Degeneration/demyelination in sciatic nerve and
atrophy/reserve cell hyperplasia of muscle
Reproductive toxicity. Alteration in sperm morphology,
reduced number of viable fetuses/litter, increased
number of resorptions/litter
Endocrine - other changes, Blood - normocytic anemia,
Nutritional and Gross Metabolic - body temperature
decrease
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „
1 8 L'
HRL Ratio(s)
NCHRL/UCMR90%: 2.46
Notes
Reference Dose; Basis LOAEL = 0.3 mg/kg-d, UF = 300, 2-year rat study. A Determination of the
Existence of a Common Mechanism of Toxicity and a Screening Level Cumulative Food Risk
Assessment, December 2001. OPP issued RfD as part of health assessment not the RED;
http://epa.gov/oppsrrd1/cumulative/thiocarb.pdf
Reference Dose; Basis NOEL 0.2 mg/kg-d; UF = 100. Stauffer Chemical Co., 1981
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 43 week study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(1 0) , 1 04, 1 975
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Molinate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 136 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621
1
0.03
5.7
5.7
5.7
5.7
5.7
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
Amount
Released
3,669,398
115
2,089
n
PWSs/Sites/Sa
mples
120
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
1.68
Number of
States
6
1
2
%
PWSs/Sites/Sam
pies with
detects
0.3
0.001
Units
States
States
States
Minimum value of
Detects
Non-cancer: 2.46
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
200
Year
1997
2004
2004
Maximum
value of
Detects
0.004
0.0372
3.41
47.9
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units
ug/L
Cancer:
Notes
Pesticide Pilot Mentoring Program (USGS/EPA)
Herbicide (HSDB)
Value
40-160
80-120
3.21
4.10E-06
970
19
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BST
Notes
BST = biodegrades sometimes/recalcitrant
-------
Molybdenum
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 137 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Molybdenum
18825
7439987
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
0.005
0.005
0.03
0.5
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
2006
Critical Effect
increased uric acid levels
Effects on repro & fetal development (decreased
gestational weight ga n, prolonged estrus cycle, failure to
breed). Renal failure, diuresis, proteinuria
Liver - other changes, Kidney, Ureter, Bladder - other
changes, Nutritional and Gross Metabolic - weight loss or
decreased weight ga n
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.2
35
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Teratogen List
Prevalence Magnitude
98 Li
HRL Ratio(s)
NCHRL/NIRS90%: 1.17
Notes
Reference Dose
Reference Dose; Koval'skiy et al.( 1961; oral study in humans; UF = 30; Basis LOAEL = 0.14 mg/kd-
d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; UL; IOM
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 9 week oral study in rabbits; VCVN5 "Vrednie chemichescie
veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic
substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.
Volume(issue)/page/year -, 317, 1989
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Molybdenum
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 138 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
77
7.79
6.1
180
10
30
110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.17
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data for molybdenum trioxide: As steel alloy; chemical reagent (HSDB); naturally-occurring
Value
1,066
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BST
Notes
assumed persistent; All use and env. fate data for molybdenum trioxide; BST = biodegrades sometimes/reca citrant
All use and env. fate data for molybdenum trioxide
-------
Nitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 139 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nitrobenzene
3998
98953
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.0005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2009
Critical Effect
Increased reticulocytesand methemaglobinemia
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1990
1996
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
14
Y/N
Y/N
ug/L
ug/L
Teratogen List
Prevalence Magnitude
1 10 NLi
HRL Ratio(s)
NCHRL/UCMRAM90%: 0.14
Notes
Reference Dose
Reference Dose; NTP, 1983; subchronic rat study; UF = 1,000; Basis BMDL = 1.8 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
CACART, IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Nitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 140 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,064
2
0.065
21. 6
100
60.8
100
100
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
UCMR finished water
HRL Ratios (HRL/UCMR AM 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
60
350,301
# PWSs/Sites
sampled
338
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
Number of
States
1
14
% PWSs/Sites
with detects
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer: 0.14
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Analyzed under UCMR 1 , List 1 , Assessment
Monitoring with detection limit of 10 ug/L.
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
Not Detected
Cancer:
Notes
Analyzed under UCMR 1, List 2, Screening Survey with detection limit of
0.5 ug/L.
Solvent (NTP)
Value
15
30.6-370
1.85
2.40E-05
1,800
31
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = biodegrades slowly
-------
Nitroglycerin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 141 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitroglycerin
2252
55630
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.125
0.008
105
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cardiac - cardiomyopathy including infarction, Cardiac
- EKG changes not diagnostic of specified effects,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - multiple enzyme effects
Behavioral - somnolence (general depressed activity)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.2
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.292
2
Y/N
Y/N
ug/L
ug/L
Teratogen
3-model Categorical Prediction
L?-L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week oral study in rats; FATOAO Farmakologiya i
Toksikologiya (Moscow), For English translation, see PHTXA6 and RPTOAN. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year
48,76,1985
Supplemental Data; RTECS LOAEL, acute human study
Oral study in rats; YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan
K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year 13,3649,1985
EPA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Nitroglycerin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 142 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0.2
55,979
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
9
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pharmaceutical/medication; production of explosives; Rocket propellants; (HSDB)
Value
1.62
9.87E-08
1,380
32
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades Fast
-------
N-Methyl-2-pyrrolidone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 143 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Methyl-2-pyrrolidone
9980
872504
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.6
120
3,914
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Decreased weight gain, neurobehavioral effects,
sedative effects
Endocrine - changes in spleen weight
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
4,200
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
10 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Tolerable Daily Intake; Basis NOAEL = 169 mg/kg-d, UF = 300, 90-day rat study, WHO/UNEP CICAD
TDI Study #35
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientif c & Technical Information. Volume(issue)/page/year
OTS0528073
Supplemental Data
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(ssue)/page/year 26,1581,1976
UMD; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
N-Methyl-2-pyrrolidone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 144 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
17,972
6,311,503
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
13
42
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical industry solvent; solvent for pesticide appl cation for food packing materials (HSDB)
Value
-0.38
3.20E-09
1,000,000
42
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades Fast
-------
N-Nitrosodiethylamine (NDEA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 145 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodiethylamine (NDEA)
2243
55185
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.00002
150
36
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.0002
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
1 2 Li
HRL Ratio(s)
See also supplemental water data No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART; EPA; OEHHA; IARC; RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitrosodiethylamine (NDEA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 146 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0
1,000
n
PWSs/Sites/Sa
mples
26
26
Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0
0
Number of
States
0
1
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Non-cancer:
Amount Range
Gasoline and lubr
Value
38
142.7
0.48
3.63E-06
106,000
53
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
Not Detected
90% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
cant additive; antioxidant; stabilizer n plastics (HSDB); Disinfection by-Product
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS/BSA
Notes
BS = Biodegrades Slowly; BSA = Biodegrades Slowly with Acclimation
-------
N-Nitrosodimethylamine (NDMA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 147 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodimethylamine (NDMA)
2446
62759
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.000008
0.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
mmunological Includ ng Allergic - decrease in cellular
immune response, Immunological Including Allergic -
decrease in humoral mmune response, Related to Chronic
Data - death
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.00007
51
16
B2
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1986
1987
Liver
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.056
0.00069
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude , „ ,
10 2 L' L
Scores based on supplemental data HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.329
CAR HRL/CAL DHS 90%: 0.004
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JTEHD6 Journal of Toxicology and Environmental Health.
(Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year 37,351 ,1992
Supplemental Data
IRIS
(Vol. 17, Suppl. 7; 1987)
CACART; RAIS; EPA; OEHHA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitrosodimethylamine (NDMA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 148 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
409
585
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
87
0
Number of
States
%
PWSs/Sites/Sam
pies with
detects
21.3
0
Units
States
States
States
Minimum value of
Detects
0.001
Not Detected
Non-cancer: 0.329
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
440
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.009
Not Detected
90% of
Detects
0.17
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer: 0.004
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwaterfPages/Chemicalconta
minants.aspx
ndustrial solvent; antioxidant; formerly in the production of rocket fuel (HSDB); Disinfection by-Product
Value
38
12
-0.57
1.82E-06
Soluble
52
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
@37°C
-------
N-Nitroso-di-n-propylamine NDPA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 149 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-di-n-propylamine (NDPA)
8798
621647
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0005
7
7
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1987
1987
Liver
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.005
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude .,, „
2 2 NL.-L,
HRL Ratio(s)
See also supplemental water data CAR HRL/STORET 90% : 0.00049
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
IRIS
CACART; EPA; RAIS; OEHHA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitroso-di-n-propylamine NDPA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 150 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (HRL/STORET 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0
506
n
PWSs/Sites/Sa
mples
127
1,309
Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0
22
Number of
States
0
2
%
PWSs/Sites/Sam
pies with
detects
0
1.68
Units
States
States
States
Minimum value of
Detects
Not Detected
0.19
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Not Detected
20
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
10
90% of
Detects
Not Detected
10.24
Units
ug/L
ug/L
Cancer: 0.00049
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Research chemical (HSDB); Disinfection by-Product?
Value
38
130
1.36
5.38E-06
10,000
44
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation
@37°C
-------
N-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 151 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodiphenylamine
3193
86306
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
20.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1966
Critical Effect
Corneal opacities, epithelial hyperplasia of the bladder
and decreased weight gain
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude ,,,
2 1 NL
HRL Ratio(s)
NC HRL/CAL DHS 90% : 1 .84
See also supplemental water data CAR HRL/CA|_ DH£. g()% . Q Og32
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NC1 1979; Basis LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 17-week oral study in rabbit; GTPZAB Gigiena Truda i
Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/paae/vear 10(4). 60.1 966
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0049
0.009
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1987
IRIS
Cited by OEHHA
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
140
7.1
Y/N
Y/N
ug/L
ug/L
CACART; EPA; OEHHA; RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
N-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 152 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
14
n
PWSs/Sites/Sa
mples
133
#with Detects
Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
1
% Samples with
detects
Number of
States
0
2
%
PWSs/Sites/Sam
pies with
detects
0.75
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
76.2
Non-cancer: 1.84
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
76.2
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
76.2
90% of
Detects
76.2
Units for Mag
data
ug/L
Cancer: 0.0932
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Rubber and polymer additive; chemical reagent (HSDB); DBP
Value
6,154
3.13
1.21E-06
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
N-Nitrosopyrrolidine (NPYR)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 153 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosopyrrolidine (NPYR)
10160
930552
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
HEALTH EFFECTS DATA1 See also supplemental water data
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.002
2.1
2.1
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1986
1987
Liver
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.02
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
IRIS
CACART; EPA; OEHHA; RAIS; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitrosopyrrolidine (NPYR)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 154 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
27
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes
Cancer:
Research chemical (HSDB)
Value
38
19
-0.19
4.89E-08
1,000,000
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation
@37°C
-------
Norethindrone (19-Norethisteron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 155 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Norethindrone (19-Norethisterone)
2525
68224
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0167
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
The norethindrone abel indicates that if the drug is
taken during the first trimester of pregnancy that the
riskfor hypospadia in male offspring doubles.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
NTP Carcinogen Classification
Reasonably antic
carcinogenic
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Dated to be
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.04
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 4
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.0459
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Daily Dose (MRDD)
NTP 1 1th Report on Carcinogens; no quantificatio of dose-response
CACART
UMD, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Norethindrone (19-Norethisteron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 156 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, et al., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
70
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
12.8
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.0459
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.872
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.048
90% of
Detects
Units for Mag
data
ug/L
Notes
National Surface Water Reconnaissance; Kolpin, etal., 2002. Env.
Sci.&Technol., 36(6), pp. 1202-1211.
Cancer:
Value
60
2.97
5.80E-10
7.04
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
n-Propylbenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 157 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
n-Propylbenzene
4328
103651
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2.5
6,040
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood - changes in spleen
Behavioral - somnolence (general depressed activity)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5.83
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
4 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 1.21
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVQH "Vrednie chemichescie veshestva,
galogenproisvodnie uglevodorodov". (Hazardous substances Qalogenated hydrocarbons)
Bandman A.L. et al., Chimia, 1990. Volume(issue)/page/year -,167,1990; 24 week oral study in rat
Supplemental Data
Rats; FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher
information, see FCTOD7. Volume(issue)/page/year 2,327,1964
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
n-Propylbenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 158 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,724
22,970
42
54
0.33
0.24
0.03
0.1
34
21
0.7
0.6
4.8
4
34
21
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
Amount
Released
# PWSs/Sites
sampled
53
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1.23
Number of
States
% PWSs/Sites
with detects
0.004
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.21
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
47
Year
Maximum
value of
Detects
0.024
5
47
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Manufacture of methylstyrene; text le dyeing; printing solvent; asphalt and naphtha constituent (HSDB)
Value
15
495-955
3.69
1.05E-02
23.4
22
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
-------
o-Toluidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 159 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
o-Toluidine
3768
95534
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
340
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Kidney, Ureter, Bladder - proteinuria, Blood - normocytic
anemia, Nutritional and Gross Metabol c - weight loss or
decreased weight ga n.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.24
0.18
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
2000
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
793
0.194
Y/N
Y/N
ug/L
ug/L
Teratogen list
Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VINIT Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii
(VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) Use information
broker to obtain publications. Vo ume(issue)/page
Supplemental Data
HEAST
Vol. 77; 2000
IARC, RAIS, OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
o-Toluidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 160 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
5
10,774
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
9
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Intermediate in the manufacture of dyes, rubber, Pharmaceuticals and pesticides (HSDB)
Value
74.04
1.32
1.98E-06
16,600
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
Oxirane, methyl-
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 161 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxirane, methyl-
2661
75569
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
26
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
ncreased combined incidence of hyperkeratosis,
hyperplasia and papillomas.
Brain and Coverings - other degeneratve changes, Liver -
other changes, Blood - other changes
Cancer Data
EPA Lifetime Cancer Risk, 10"*
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.15
0.24
0.24
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1990
1994
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
60.7
0.233
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose; Basis = BMDL „ 1 .4 mg/kg-d; UF = 1 000.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 45-day study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(7), 76,1 981
Supplemental Data
CACART; RAIS; OEHHA; EPA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Oxirane, methyl-
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 162 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
28,761
433,536
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
5
28
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (NTP)
Value
2.324
0.03
6.98E-05
590,000
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BS
Notes
PBT; BS = biodegrades slow
-------
Oxydemeton-methyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 163 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxydemeton-methyl
6458
301122
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00013
0.0025
10
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
Decreased erythrocyte & brain ChE
Decreased body weight
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.91
Y/N
Y/N
ug/L
ug/L
male, female
Prevalence Magnitude
95 Li
HRL Ratio(s)
NC HRL/SWC EEC: 1.01
Notes
Reference Dose; Basis = NOAEL 0.013 mgfkg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
85JDAH "Organophosphorus Pesticides Organic and Biological Chemistry," Eto, M., Cleveland, OH, CRC
Press, Inc., 1974 Volume(issue)/page/year -,197,1974
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Oxydemeton-methyl
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 164 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
154,227
0
0
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
19
0
0
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Surface water chronic: 0.9 ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic: 0.006 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.01
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
nsecticide (HSDB)
Value
-0.74
1.62E-13
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS =Biodegrades Slowly
-------
Oxyfluorfen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 165 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxyfluorfen
34731
42874033
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.003
5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
ncr. abs. liver weight; nonneoplastic lesions
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0732
C
mg/L
(mg/kg-d)-'
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
21
0.478
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 6 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 3.0
CAR HRL/SWC EEC: 0.067
Notes
Reference Dose
Reference Dose; Basis = NOEL 0.3 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,643,1991
EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Oxyfluorfen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 166 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
705,255
0
5
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
37
0
2
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 7.1 ug/L
Non-cancer: 3.0
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic: 0.08 ug/L
Cancer: 0.067
Pesticide; herbicide
Value
46,800
4.73
8.23E-07
0.116
5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = biodegrades sometimes/recalcitrant; PBT
-------
Perchlorate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 167 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perchlorate
24310
14797730
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0007
6
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
ug/L
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2005
2000
Critical Effect
Radioactive iodide uptake inhibition (RAIU) in the
thyroid
Decreased newborn TSH
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
See notes
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-lnterimHA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
15
4.9
Y/N
Y/N
ug/L
ug/L
ug/L
Teratogen
Prevalence Magnitude .,, „
9 8 NL!'L!
HRL Ratio(s)
NCHRL/UCMR90%: 0.35
Notes
Reference Dose
Reference Dose; Basis NOEL 0.007mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Brechner et al. 2000
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Not likely to pose a risk of thyroid cancer in humans, at least at doses below those necessary to alter
thyroid hormone homeostasis, based on the hormonally-mediated mode of action in rodent studies and
species differences in thyroid function (IRIS).
UMD
Interim Health Advisory; EPA is revisiting the intermin hHealth Advisory for perchlorate.
The HRL for the CCL differs from the Interim HA based on the RSC used in the health advisory (0.62)
and the default RSC (0.2) used for the CCL process.
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Perchlorate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 168 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,554
147
4.14
4
420
6.5
14
59
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.35
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Smokeless rocket and jet propellant; explosives; analytical chemistry, etch ng and engraving agent (HSDB)
Value
200,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
All use and env. fate data are for ammonium perchlorate.
-------
Perfluorooctane sulfonic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 169 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perfluorooctane sulfonic acid (PFOS)
12176
1763231
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
EPA/FR NOAEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.03
251
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Reduced F2 Body Weight
Decreased body weights, increased liver weights,
lowered serum total cholesterol, lowered
triiodothyronine (T3) concentration, and lowered
estradiol levels
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-Provisional HA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.2
0.2
Y/N
Y/N
ug/L
ug/L
ug/L
January 2008
Prevalence Magnitude , „ ,
10 7 L' L
HRL Ratio(s)
NC HRL/MN MW MAX: 0.143
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
No Observed Adverse Effect Level in 2 generation reproductive study in rats. Supplemental Data - FR
October 18, 2000 (Volume 65, Number 202)] Perfluorooctyl Sulfonates; Proposed Significant New Use
Rule [Page 6231 9-62333]
Supplemental Data - Seacat et al., 2002, Toxicol. Sci. 68, 249-264. EPA Provisional HA:
http://www.epa.gOV/waterscience/criteria/d rinkinglpha-PFOA_PFOS.pdf
Lowest Observed Adverse Effect Level
Provisional Health Advisory: http://www.epa. gov/waterscience/criteria/drinking/pha-PFOA_PFOS.pdf
Note: HRL is based on adult exposure factors (70 kg body weight and 2 L/d ingestion). The HRL was
calculated in a d fferent manner than EPA's provisional HA because child exposure factors and
toxicokinetic adjustments were used to derive the provisional HA.
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Perfluorooctane sulfonic acid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 170 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Select New Jersey Water Systems
Select Minnesota municipal wells
Select Minnesota non-community wells
Select Minnesota private wells
Aggregate of above Minnesota wells
HRL Ratios (HRL/MN MW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
23
37
22
26
85
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
13
6
0
0
6
Number of
States
%
PWSs/Sites/Sam
pies with
detects
57%
16.2%
0%
0%
7.1%
Units
States
States
States
Range of Detects
(ug/L)
0.0042-0.019
ND-1.4
ND
ND
ND-1.4
Non-cancer: 0.143
Amount Range
10-500K
0
Units
Ibs/yr
Ibs/yr
Year
2002
2003 (EPA est.)
Year
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Notes
Targeted Sampl ng 2006 - Targeted study "Determination of Perfluorooctanoic Acid (PFOA) in Aqueous Samples, Final Report." Jan 2007,
NJDEP, Division of Water Supply.
Targeted Sampling 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Cancer:
Estimate of zero as phased out.
Surface-active agents in aqueous media; chemical intermediate; in fire-fight ng applications, floor polish; metal plating baths; pest c de active ingred ent for ant bait traps. (HSDB)
Value
100,000
370
Units
length of time
L/kg
unitless
cm3/g
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = biodegrades sometimes/recalcitrant
-------
Perfluorooctanoic acid (PFOA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 171 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perfluorooctanoic acid (PFOA)
6614
335671
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.46
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
Critical Effect
Increased maternal liver weight at term
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-Provisional HA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.4
1.1
Y/N
Y/N
ug/L
ug/L
ug/L
January 2008
Prevalence Magnitude
10 6
Scores based on supplemental data HRL Ratio(s)
NC HRL/MN MW MAX: 1.22
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data (BMDL10), Lau, 2006. Tox. Sci., 90, 2, pp. 510-518. EPA Provisional HA:
http://www.epa.goV/waterscience/criteria/d rinking/pha-PFOA_PFOS.pdf
Provisional Health Advisory: http://www.epa. gov/waterscience/criteria/drinking/pha-PFOA_PFOS.pdf
Note: HRL is based on adult exposure factors (70 kg body weight and 2 L/d ingestion). This value differs
from EPA's provisional HA because child exposure factors and toxicokinetic adjustments were used to
derive the provisional HA.
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Perfluorooctanoic acid (PFOA)
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 172 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
NJDEP - Jan 2007
Little Hocking, OH Municipal Wells (FW)
Select Minnesota municipal wells
Select Minnesota non-community wells
Select Minnesota private wells
Aggregate of above Minnesota wells
HRL Ratios (HRL/MN MW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
23
No data
37
22
26
85
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
18
6
0
1
7
Number of
States
%
PWSs/Sites/Sam
pies with
detects
78
16.2%
0%
3.8%
8.2%
Units
States
States
States
Range of Detects
(ug/L)
<0.004 - 0.039
1.5-7.2
ND-0.9
ND
ND-0.67
ND-0.9
Non-cancer: 1.22
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Notes
Targeted study ' Determination of Perfluorooctanoic Ac d (PFOA) in Aqueous Samples, Final Report." Jan 2007, NJDEP, Division of Water
Supply.
Emmett, et al., 2006. J. Occ. Env. Med. Little Hocking, OH; data from 2002-2005.
Targeted Sampling 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Cancer:
Production of fluoropolymers (e.g., Teflon) and fluoroelastomers; in fire-fight ng applications, cosmetics, greases and lubricants, pa nts, polishes and adhesives (HSDB)
Value
180
27,000
9.10E-02
1
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
PBT; BST = biodegrades sometimes/recalcitrant
-------
Permethrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 173 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Permethrin
35815
52645531
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.25
0.05
0.05
0.2
0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1999
Critical Effect
Neurotox (aggression, abnormal/ decreased movement),
increased body temperature. Q1* 0.0096 (mg/kg/day)-1.
See CAR
ncreased liver weight
Neurol.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0096
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,750
3.65
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 7 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 1,944
CAR HRL/SWC EEC: 4.05
Notes
Reference Dose; Basis = NOAEL 25 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 5 mg/kd-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level; ATSDR MRL-int.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Permethrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 174 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
1,066,056
0
17,979
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
48
0
7
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 0.9 ug/L
Ground water chronic: 0 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1,944
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 4.05
nsecticide (HSDB)
Value
178,000
6.5
1.87E-06
0.006
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF/BST
Notes
BF = biodegrades fast; BST = biodegrades sometimes/reca c trant
-------
Profenofos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 175 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Profenofos
34318
41198087
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
0.0004
0.05
162
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Inhibition of plasma & RBC ChE activity
Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase
Behavioral - somnolence (general depressed activity),
Behavioral - tremor, Gastrointestinal - changes in structure
or function of salivary glands
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 3.5
Notes
Reference Dose; Basis = NOEL 0.005 mg*g-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 12,781,1987
Supplemental Data
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 73,16,1984
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Profenofos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 176 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
879,776
0
255
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
14
0
1
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 0.1 ug/L
Non-cancer: 3.5
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic: 0.03 ug/L
Cancer:
Pesticide, insecticide, acaricide (HSDB)
Value
4.68
2.21 E-08
28
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = biodegrades sometimes/recalcitrant; PBT
-------
Quinoline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 177 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quinoline
3467
91225
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.001
3
B2
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
2001
2001
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.01
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
L?-L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
IRIS
IRIS
Hirao et al., 1976; oral study in rats
CACART, EPA, RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Quinoline
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 178 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
62
28,629
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
8
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; pharmaceutical (anti-malarial); flavoring (HSDB)
Value
1,837
2.03
1.67E-06
6,110
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades Fast with Acclimation
-------
RDX
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 179 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
RDX
5404
121824
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.003
0.003
0.03
40
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
2006
6/1995
Critical Effect
nflammation of the prostate.
Cardiac - other changes, Blood - pigmented or nucleated
red blood cells, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.03
0.11
c
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1988
1988
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
21
0.3
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Teratogen
Prevalence Magnitude
5 5 Li
HRL Ratio(s)
NCHRL/STORET90%: 0.092
CARHRL/STORET90%: 0.0013
Notes
Reference Dose
Reference Dose; Basis NOEL 0.3 mg/kg-d. U.S. DOD, 1983
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year AD-A092-531
Supplemental Data
EPAHA
EPA; RAIS
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
RDX
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 180 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental water data
STORE!
HRL Ratios (HRL/STORET 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
23
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
23
Number of
States
%
PWSs/Sites/Sam
pies with
detects
100
Units
States
States
States
Minimum value of
Detects
15
Non-cancer: 0.092
Amount Range
>500K - 1 M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
270
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
140
90% of
Detects
229
Units
ug/L
Cancer: 0.0013
Notes
High explosive
Value
195.4
0.87
6.30E-08
59.7
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = biodegrades fast with acclimation
-------
sec-Butyl benzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 181 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
sec-Butylbenzene
5904
135988
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4.42
2,240
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral -alteration of classical conditioning
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
10.3
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
3 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 1.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 24-week oral rat study; VCVGH "Vrednie chemichescie
veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances Galogenated
hydrocarbons) Bandman A.L. etal., Chimia, 1990. Volume(issueXpage/year -,179,1990
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
sec-Butyl benzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 182 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,343
22,974
28
34
0.227
0.148
0.03
0.1
19.8
22
0.7
0.6
10
4.6
19.8
22
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
Amount
Released
# PWSs/Sites
sampled
25
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0.58
Number of
States
% PWSs/Sites
with detects
0.005
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.03
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
11
Year
Maximum
value of
Detects
0.39
2.81
11
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent for coating compositions, organic synthesis, plasticizer, and surface active agents (HSDB)
Value
15
7,200
4.57
1.80E-02
17.6
15
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = biodegrades slowly
-------
Strontium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 183 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Strontium
18848
7440246
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.6
0.6
0.6
2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
2006
2004
Critical Effect
Rachitic bone
Musculo-skeletal effects
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
20
4,200
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Prevalence Magnitude
10 10 Li
HRL Ratio(s)
NCHRL/NIRS90%:3.88
Notes
Reference Dose
Reference Dose; Storey, 1961 ; Marie et al., 1985; Skoryna, 1981; UF = 300; Rat; Basis NOAEL = 190
mg/kg-d
Reference Dose
Reference Dose; IRIS
Minimal Risk Level; UF = 30; MRL-Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Strontium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 184 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
980
99.1
1.5
43,550
178
1,080
7,340
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 3.88
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for strontium carbonate: In pyrotechnics; steel production; catalyst; lead scavenger (HSDB); naturally-occurring
Value
11
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BST
Notes
assumed persistent; All use and env. fate data are for strontium carbonate; BST = biodegrades sometimes/recalcitrant
-------
Tebuconazole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 185 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tebuconazole
69191
107534963
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.029
0.03
1,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2008
1994
Critical Effect
Decreased body weights, absolute brain weights, brain
measurements and motor activity in offspring
Behavioral - food intake (animal)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
2008
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
96 L' L
HRL Ratio(s)
NC HRL/GWC EEC: 9.09
Notes
Reference Dose; Basis = LOAEL 8.8 mg/kg-d; UF = 300. Federal Register: May 14, 2008 (Volume
74, Number 94), pp 27748-27756.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Oral study- rabbit; NTIS Nationa Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0545183
OPP; 73 FR No. 94, pp 27748-27756.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tebuconazole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 186 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
478,568
Units
Ibs/yr
Ibs/yr
Ibs/yr
Number of
States
16
Units
States
States
States
Year
1997
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 14 ug/L
Ground water chronic: 23.1 ug/L
HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 9.09
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
Fungicide (HSDB)
Value
3.7
1.45E-10
36
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
PBT; BST = biodegrades sometimes/recalcitrant
-------
Tebufenozide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 187 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tebufenozide
69514
112410238
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018
0.02
8.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
2003
Critical Effect
Growth retardation, alterations in hematology
parameters, changes in organ weights, and
histopathological lesions in the bone, spleen and liver
Effect on erythrocytes, periferal hemolytic anaemia. Gross
and histopathologica lesions in the spleen (congestion,
pigment, and extra-medullary haematopoiesis)
Blood - normocytic anemia, Blood - thrombocytopenia
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
126
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
9 5 Li
HRL Ratio(s)
NC HRL/SWC EEC: 8.4
Notes
Reference Dose; Basis NOAEL = 1 .8 mg/kg-d, UF = 100. Federal Register 64 FR, No. 203, pp
56690-56697, October 21, 1999.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year study in dog; FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year 64, 16851, 1999
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tebufenozide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 188 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
104,413
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
17
Units
States
States
States
Year
1997
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 15 ug/L
Ground water chronic: 1.19ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.4
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
nsecticide (HSDB)
Value
4.25
1.26E-08
0.83
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
PBT; BST = biodegrades sometimes/recalcitrant
-------
Tellurium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 189 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tellurium
23035
13494809
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
25
20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Maternal toxicity
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
175
Y/N
Y/N
ug/L
ug/L
Teratogen
Prevalence Magnitude
49 Li
HRL Ratio(s)
NCHRL/NIRS 90%: 0.673
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; No Observed Effect Leve ; Johnson et al., 1988
Lowest Observed Adverse Effect Level
Supplemental Data
Mouse; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
Izmerov, N.F., et al., Moscow, Centre of Internatonal Projects, GKNT, 1982 Volume(issue)/page/year -
,107,1982
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tellurium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 190 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
4
0.4
15
370
22
260
360
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.673
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for sodium tellurite: Bacteriology, medicine (HSDB); naturally-occurring
Value
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L
Degradation
Code
BST
Notes
assume persistent; All use and env. fate data are for sodium tellurite; BST = biodegrades sometimes/recalcitrant
-------
Terbufos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 191 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Terbufos
22585
13071799
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
0.00005
0.000025
0.0002
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
1989
Critical Effect
Plasma ChE inhibition
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1988
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.002
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
2006
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1.67
Notes
Reference Dose; Basis = NOAEL 0.005 mgrtsg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer classifications were used for screening, but no related quantitative cancer risk data were identified for
potency scoring.
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Terbufos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 192 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,,2, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
Amount
Released
6,515,603
n
PWSs/Sites/Sa
mples
n
PWSs/Sites/Sa
mples
61
915
22
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
#with Detects
0
11
0.31
Number of
States
37
%
PWSs/Sites/Sam
pies with
detects
0
0
%
PWSs/Sites/Sam
pies with
detects
0
1.2
0.0021
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
0.1
Non-cancer: 1.67
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.56
Year
1997
Maximum value
of Detects
Not Detected
Not Detected
Maximum value
of Detects
3.2
0.017
0.21
0.56
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.185
95% of Detects
Not Detected
Not Detected
90% of Detects
0.202
Notes
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:
Pesticide Pilot Mentoring Program (USGS/EPA)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
nsecticide (HSDB)
Value
38
500-5,000
4.48
2.40E-05
5.07
14
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = biodegrades slowly with acclimation
-------
Terbufos sulfone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 193 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Terbufos sulfone
37071
5607016
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
1 1
Scores based on parent Scores based on parent
HEALTH EFFECTS DATA1 - See parent Terbufos
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Plasma ChE inhibition
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
ug/L
ug/L
3-model Categorical Prediction
NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 .67 (NAWQA data and HRL
for parent terbufos)
Notes
Reference Dose - FOR PARENT TERBUFOS
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
Based on data for parent terbufos
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Terbufos sulfone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 194 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Finished Water Occurrence Data FOR TERBUFOS - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
0
0
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data FOR TERBUFOS - PARENT
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
FOR TERBUFOS - PARENT
CAL DHS
STORE!
PPMP finished water
PPMP ambient water
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
Amount
Released
n
PWSs/Sites/Sa
mples
61
915
22
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
11
2
0
0.31
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0
1.2
0.9
0
0.0021
Units
States
States
States
Minimum value of
Detects
0.1
Non-cancer: 1.67
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.56
Year
Maximum value
of Detects
3.2
0.016
0.017
0.21
0.56
Units for Mag
data
ug/L
mg/L
mg/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.185
90% of Detects
0.202
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
Cancer:
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Pesticide Pilot Montoring Program (USGS/EPA) FROM TERBUFOS O-
ANALOGUE SULFONE
Pesticide Pilot Montoring Program (USGS/EPA) FROM TERBUFOS O-
ANALOGUE SULFONE
NAWQA data and HRL for Parent Terbufos
Pesticide degradate
Value
38
2.21 E-08
21
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with ace mation
-------
Thiodicarb
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 195 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Thiodicarb
38116
59669260
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.03
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
2000
Critical Effect
Extramedulary hematapoesis and decreased red blood cell
cholinesterase activity
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0188
B2
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
210
1.86
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 6 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 8.1
CAR HRL/SWC EEC: 0.07
Notes
Reference Dose; Basis NOEL = 3.3 mg/kg-d (males) and 4.5 mg/kg-d (females); UF = 100; chronic rat
study.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
CACART; EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thiodicarb
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 196 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
821,267
0.05
1,430
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
27
1
3
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 26 ug/L
Ground water chronic: 0 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.1
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.07
nsecticide (HSDB)
Value
1.7
9.33E-07
35
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
-------
Thiophanate-methyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 197 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Thiophanate-methyl
27753
23564058
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.08
0.08
0.08
0.08
1.2
2,270
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2004
1986
1998
Critical Effect
Thyroid and liver effects and decreased body weight
Decreased body weight, decreased spermatogenesis and
histological evidence of hyperthyroidism
Endocrine - evidence of thyroid hypofunction, Endocrine -
changes in thyroid weight, Nutritional and Gross Metabolic
- weight loss or decreased weight gain
Sense Organs and Special Senses (Eye) - mydriasis
(pupillary dilation), Behavioral - somno ence (general
depressed activity), Behavioral - convulsions or effect on
seizure threshold
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0116
C
mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
560
3.02
Y/N
Y/N
ug/L
ug/L
Female & male reproductive toxicity
Prevalence Magnitude , „ ,
10 6 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 45.9
CAR HRL/SWC EEC: 0.248
Notes
Reference Dose; Basis NOEL = 8 mg/kg-d; UF = 100; chronic dog study.
Reference Dose; Basis = NOEL 8 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FEREAC Federal Register. (U.S. Government Printing Office,
Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year 67,14944,2002
Supplemental Data
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 23,606,1972
OPP
EPA
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thiophanate-methyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 198 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
453,792
0
92
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
40
0
3
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 12.2 ug/L
Ground water chronic: 3.03 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 45.9
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.248
Fungicide (HSDB)
Value
14.32
1.4
2.94E-13
438.9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = biodegrades fast
-------
Toluene diisocyanate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 199 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Toluene diisocyanate
29421
26471625
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD501
CTDJPN Lowest Oral LD501
RTECS Lowest Oral LD501
Value
30
85.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Burns throat immediately.
Related to Chronic Data - death
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.039
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
210
0.9
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-251,1986
Supplemental Data
Applies to m ixture of 2,4- and 2,6- isomers.
CACART; IARC; OEHHA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Toluene diisocyanate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 200 of 1124
OCCURRENCE DATA
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
1
129,143
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
1
31
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M - 1 B
>500M - 1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n plastics manufacture (NTP)
Value
9,114
3.74
1.11E-05
37.57
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
-------
Tribufos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 201 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tribufos
2814
78488
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.00003
0.00003
4.08
77
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Plasma ChE inhibition
Gastrointestinal - other changes, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
other hydrolases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - peptidases
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
98 Li
HRL Ratio(s)
NC HRL/SWC EEC: 3.89
Notes
Reference Dose; Basis = NOAEL 0.1 mg/kg-d; UF = 100.
Reference Dose; Basis NOAEL 0.1 mg/kg-d; Abou-Donia etal., 1979
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 43 week study in rodent; FATOAO Farmakologiya i Toksikologiya
(Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.2- 1939- Volume(issue)/page/year 38,96,1975
Supplemental Data
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1188,1986
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tribufos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 202 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
4,918,265
4
7
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
16
1
1
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Surface water chronic 1.8ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic 0 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 3.89
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
nsecticide; cotton defoliant (HSDB)
Value
1,888
5.7
2.94E-07
2.3
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BF
Notes
BF = biodegrades fast
-------
Triethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 203 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Triethylamine
5379
121448
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1
460
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Brain and Coverings - other degenerative changes
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2.33
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 9
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-week oral rat study; WDZAEK Weisheng Dulixue Zazhi.
Journal of Health Toxicology. (Weisheng Du ixue Zazhi Bianjibu, Dongdaqiao, Chaoyang Menwai,
Beijing, Peop. Rep. China) V.1- 1987 Volume(issue)/page/year 4,45,1990
Supplemental Data
AMIHBCAMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54.
For publisher information, see AEHLAU. Volume(ssue)/page/year 4,119,1951
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Triethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 204 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
12,000
1,167,219
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
14
35
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; stabilizer; in herbicides/pest c des; in consumer products; food addit ve; photographic chemical; in carpet c eaners (HSDB)
Value
107.2
1.45
1.49E-04
73,700
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = biodegrades slowly with acclimation
-------
Triphenyltin hydroxide (TPTH)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 205 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Triphenyltin hydroxide (TPTH)
2738
76879
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0003
0.0005
0.15
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1970
Critical Effect
Decreased white blood cells
Blood - changes in other cell count (unspecified), Blood -
changes in leukocyte (WBC) count
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
18.3
B2
mg/L
(mg/kg-d)-'
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
2.1
0.0019
Y/N
Y/N
ug/L
ug/L
Teratogen; Developmental
Prevalence Magnitude
10 6
HRL Ratio(s)
NC HRL/SWC EEC: 0.33
CAR HRL/SWC EEC: 0.0003
Notes
Reference Dose; OPP RED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in guinea pig; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year4,35,1966
Supplemental Data
EPA; CACART
UMD; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Triphenyltin hydroxide (TPTH)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 206 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
660,971
0
0
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
26
0
0
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic 6.4 ug/L
Ground water chronic 0 ug/L
Notes
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.33
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.0003
Pesticide (NTP)
Value
2,000
3.53
4.26E-07
0.4
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Urethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 207 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Urethane
2189
51796
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.9
78
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2005
Critical Effect
Decreased survival
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - changes in leukocyte
(WBC) count
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
1
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
6.3
0.035
Y/N
Y/N
ug/L
ug/L
Developmental
Teratogen
Prevalence Magnitude ,
7 6 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Food and Chemical Toxicology 43 (2005) 1-19
Lowest Observed Adverse Effect Level; 1 3 week oral study in rats; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NIH-96-
3937
Supplemental Data
Vol. 7, Suppl. 7; 1987
IARC; CACART; OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Urethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 208 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0
96,050
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
0
7
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Paint ingredient (NTP)
Value
-0.15
6.40E-08
480,000
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = Biodegrades Slowly
-------
Vanadium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 209 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Vanadium
18882
7440622
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.007
0.003
1.8
960
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
2001
Critical Effect
Minor renal effects (altered renal function as indicated
by increased plasma urea, and mild histological
changes).
Kidney lesions and increases in plasma urea and uric acid
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
21
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude , „ ,
10 8 Li L
HRL Ratio(s)
NCHRL/NIRS90%:0.913
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; HEAST
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; IOM 2001 Dietary Reference ntakes
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; Domestic mammal
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vanadium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 210 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
146
14.76
3.1
70.4
7.27
23
45
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.913
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for vanadium pentoxide: Chemical intermediate; catalyst; (HSDB); naturally-occurring
Value
8,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; All use and env. fate data are for vanad um pentoxide; BST = biodegrades sometimes/recalcitrant
-------
Vinclozolin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 211 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Vinclozolin
35005
50471448
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.012
0.025
0.025
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1995
Critical Effect
Histopathological les ons in the lungs, iver, ovaries &
eyes. Q1 * 0.0638 (mg/kg-day)-1 .Group C. See CAR
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0638
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
84
0.549
Y/N
Y/N
ug/L
ug/L
Developmental
Prevalence Magnitude , „ ,
10 5 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 8.94
CAR HRL/SWC EEC: 0.058
Notes
Reference Dose; Basis = NOAEL 1 .2 mg/kg-d; UF = 1 00.
Reference Dose; Basis = NOEL 2.5 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
EPA
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vinclozolin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 212 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
121,959
0
0
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
26
0
0
Units
States
States
States
Year
1997
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 9.4 ug/L
Ground water chronic: 0 ug/L
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.94
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer: 0.058
Fungicide (HSDB)
Value
289
3.1
1.33E-08
2.6
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = biodegrades sometimes/recalcitrant
-------
Ziram
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 213 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ziram
5947
137304
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.016
0.003
1.6
1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Decreased body weight gain
Decreased body weight
Gastrointestinal - hypermotility, diarrhea
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0611
Suggestive (not
quantified)
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
112
0.57
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude ,
10 7 L
HRL Ratio(s)
NC HRL/SWC EEC: 56.6
CAR HRL/SWC EEC: 0.288
Notes
Reference Dose; Basis = NOAEL 1 .6 mg/kg-d; UF = 1 00.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; Group ADI for Ferbam and Ziram
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
OPP
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 17,3155,1992
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ziram
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 214 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Amount
Released
1,992,552
Units
Ibsfyr
Ibs/yr
Ibs/yr
Number of
States
29
Units
States
States
States
Year
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 1 .98 ug/L
Non-cancer: 56.6
Amount Range
>500K - 1 M
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Ground water chronic: 0.03 ug/L
Cancer: 0.288
Synthetic rubber chemical (NTP); fungicide
Value
6.20E-10
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades Fast with Acclimation
-------
(d)-Limonene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 215 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
(d)-Limonene
17273
5989275
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
IPCS-CICAD TDI
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
500
30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
Critical Effect
ncreased relative liver weight
Decreased body weight gain
Kidney, Ureter, Bladder - other changes in urine
composition, Kidney, Ureter, Bladder - other changes
Prevalence Magnitude
9 6 NLi
HRL Ratio(s)
NC HRL/NREC ASW MED: 700
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
IPCS Tolerable Daily Intake
No Observed Effect Level
Supplemental Data; NTP Study Report TR-347
Lowest Observed Adverse Effect Level; oral study in rat; FCTOD7 Food and Chemical Toxicology.
(Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year31,125,1993
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
700
Y/N
Y/N
ug/L
ug/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
(d)-Limonene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 216 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NREC ASW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
6.39
1.47
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 700
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
1
0.39
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Used in flavorings, fragrances, cosmetics, as a solvent, wetting agent and the manufacture of resins, insecticide, synthetic intermediate (HSDB)
Value
1,300
4.57
0.026
13.8
19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
Biodegrades slow (PBT)
-------
(Hydroxyimino)cyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 217 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
(Hydro xyiminojcyclohexane
4125
100641
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
17.86
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Endocrine - changes in spleen weight, Blood -
changes in erythrocyte (RBC) count, Blood - changes
in leukocyte (WBC) count
Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information,
see TOSCF2 Volume(issue);pagefyear5,117,1985
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
41.7
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
(Hydroxyimino)cyclohexane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 218 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
0.84
8.05E-06
18,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1,1,1 -Trichloropropanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 219 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1 ,1 ,1 -Trichloropropanone
10061
918003
Attribute Scores
Potency Severity
Prevalence Magnitude
10 7
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
HRL Ratio(s)
No HRL data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 ~6 cancer risk was used.
-------
1,1,1 -Trichloropropanone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 220 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
53
16.97
1.7
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006 and related
documentation
HRL Ratios (no HRL data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
12
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
10
Number of
States
% PWSs/Sites/
Samples w/
Detects
83
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
7
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.8
90% of
Detects
Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci. &
Technol., 40(23), pp. 7175-7185 (and related documentation).
Cancer:
Disinfection By-Product
Value
60 days
8.7
1.12
2.20E-06
7,450
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
1,1,2,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 221 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,1 ,2,2-Tetrachloroethane
2878
79345
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
0.06
0.04
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Decreased body weights; increased white blood cell
counts, hepatic fat content and pituitary ACTH content
Hepatocellular vacuo zation and increases in absolute
and relative
Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.13
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL rat, Microbioligica Associates, 1994. UF = 300
Minimal Risk Level; Basis LOAEL 43, rat, NCI 1 987; UF = 1 ,000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.02
0.2
0.27
C
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.002
0.35
Y/N
Y/N
mg/L
ug/L
ug/L
EPA; RAISHE; OEHHA; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1,1,2,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 222 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
20,407
24,800
91
19
0.446
0.0766
0.05
0.1
200
2
0.5
0.5
2.74
1.5
112
2
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,317
# Sam pies
Amount
Released
5
3,185
# PWSs/Sites/
Samples
134
3
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0.069
% Samples with
detects
Number of
States
1
5
% PWSs/Sites/
Samples with
detects
0
0.02
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.13
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.38
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
0.14
Median value of
Detects
0.38
90% of
Detects
0.38
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
ndustrial solvent; former pesticide; in manufacture of paints, varnish, rust removers; in soil sterilization and weed k Her, insecticide formulations; chemical intermediate (HSDB)
Value
>58 days
106.8
2.39
0.00037
2,870
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
1,2,3,4-Tetrahydronapthalene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 223 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,3,4-Tetrahydronaphthalene
5285
119642
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,860
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
1982
Critical Effect
Cataract
Prevalence Magnitude
7 3 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Ref: Hayes, Wayland J., Jr. Pesticides Studied in Man. Baltimore/London: Williams and Wilkins
1982., p.122
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,2,3,4-Tetrahydronapthalene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 224 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; paint remover; nsecticide (HSDB)
Value
1,800
0.0017
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
PBT
-------
1,2,3-Trichlorobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 225 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,3-Trichlorobenzene
3257
87616
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0015
7.7
77.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg(kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
1988
Critical Effect
Mild to moderate histopathological changes in the
liver, thyroid and Wdney
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Nutritional and Gross
Metabolic - weight loss or decreased weight gain
Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 18
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER. Ref: HC2004. Basis NOEL, rat, Cote, etal., 1988. UF =5000
Lowest Observed Adverse Effect Level; oral study in rat; DCTODJ Drug and Chemical Toxicology.
(Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year
11,11,1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
53.9
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1,2,3-Trichlorobenzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 226 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,876
22,532
63
43
0.489
0.191
0.04
0.03
15
2.4
0.5
0.5
3
1.4
15
2.4
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,833
3
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
6
0.07
% Samples with
detects
Number of
States
% PWSs/Sites/
Sam pies with
detects
0.05
0.02
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.6
Non-cancer: 18
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.102
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
7
0.068
Median value of
Detects
0.102
90% of
Detects
0.102
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.7
90% of
Detects
6.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
ndustrial solvent; chemical intermediate; termite control (HSDB)
Value
2,500-63,000
4.05
0.0012
18
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
1,2,4,5-Tetrachlorobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 227 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,4,5-Tetrachlorobenzene
3799
95943
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0003
0.003
0.00021
0.0432
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1992
1988
Critical Effect
Kidney lesions
Liver - changes in liver weight
Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis NOAEL = 0.34, rat, Chu et al. 1984. UF = 1000
Reference Dose
Reference Dose; Basis NOAEL, rat, Chu etal. 1984. UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; ITER. Basis NOAEL = 2.1 mg-kg/d, rat, NTP 1991. UF = 10,000
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB92-1 28388
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2.1
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,2,4,5-Tetrachlorobenzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 228 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate for herbicides; former insectic
Value
60 days
1,186
4.64
0.001
0.595
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
de (HSDB)
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
1,2,4-Trimethyl benzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 229 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,4-Trimethylbenzene
3775
95636
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
100
114
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
Critical Effect
dec in body wt gain; clinical observations; inc
iver/kidney wt
Peripheral Nerve and Sensation - recording from afferent
nerve, Peripheral Nerve and Sensation - recording from
peripheral motor nerve, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Prevalence Magnitude
6 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL, rat, IITR1 1995. UF = 3000.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; JJATDK JAT, Journal of Applied Toxicology.
(John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO191UD, UK) V.1- 1981-
Volume(issue)/page/year 13,123,1993
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
350
Y/N
Y/N
ug/L
ug/L
1987
EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,2,4-Trimethyl benzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 230 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,755
22,968
106
177
0.831
0.771
0.02
0.1
77
137
1
0.8
10
5.6
65.6
70.6
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,233
# Sam pies
Amount
Released
5,676
7,700,757
# PWSs/Sites/
Samples
11,886
473
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
35
11.2
% Samples with
detects
Number of
States
37
54
% PWSs/Sites/
Samples with
detects
0.29
0.003
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Non-cancer: 350
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
260
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
19
0.024
Median value of
Detects
0.201
90% of
Detects
10
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
90% of
Detects
5.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermed ate; vermifuge (HSDB)
Value
718
3.63
0.0062
0.252
57
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
1,2-Diphenylhydrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 231 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2-Diphenylhydrazine
5454
122667
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude .,, .,, „
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
0.005
0.8
0.87
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
1986
IRIS
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.05
Y/N
Y/N
ug/L
ug/L
EPA; RAIS; OEHHA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,2-Diphenylhydrazine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 232 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
5
# PWSs/Sites/
Samples
65
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
0
1
% PWSs/Sites/
Sam pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Not Detected
Median value of
Detects
90% of Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of Detects
Not Detected
Units for Mag
data
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermediate; evaluated as insecticide (HSDB)
Value
3,481
2.94
4.38E-09
221
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades sow with acclimaton (BIODEG)
-------
1,2-Epoxy-4-(epoxyethyl)cyclohe
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 233 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,2-Epoxy-4-(epoxyethyl)cyclohexane
4566
106876
Attribute Scores 3-model Categorical Prediction
Potency Severity
8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
1 7
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1994
Vol. 60; cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
ug/L
ug/L
IARC, CACART; Clear evidence of carcinogenicity in male and female rats and mice (NTP).
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,2-Epoxy-4-(epoxyethyl)cyclohe
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 234 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical and polymer intermediate (HSDB)
Value
1 5 days
0.44
1.42E-07
35,200
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1,3-Cyclopentadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 235 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Cyclopentadiene
7730
542927
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
113
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 8 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0535718
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7.91
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,3-Cyclopentadiene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 236 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
89.7
2.25
0.00793
471
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1,3-Dibromo-5,5-dimethylhydanto
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 237 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,3-Dibromo-5,5-dimethylhydantoin
2748
77485
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.437
250
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Endocrine - evidence of thyroid hypofunction
Prevalence Magnitude
3 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volu me(issue)/page/year 36(1 0),1 08,1 971
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.02
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,3-Dibromo-5,5-dimethylhydanto
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 238 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Molluscicide; slim
Value
38 days
-0.94
51
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
cide (ChemlDPIus)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
1,3-Dichloropropene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 239 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Dichloropropene
7722
542756
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.02
0.03
0.03
2.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Decreased body weight gain and increased incidence of
basal cell hyperplasia of the nonglandular mucosa of the
stomach
forestomach
chronic irritation
Gastrointestinal - changes in structure or function of
endocrine pancreas, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
hydrolases
Prevalence Magnitude
4 6 Li
HRL Ratio(s)
NC HRL/NCOD R1 90%: 97.2
CAR HRL/NCOD R1 90%: 0.16
Notes
Reference Dose; Stott, et al. 1995
Reference Dose, Stott etal., 1995, Basis BMD = 2.2 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, Stott etal., 1995, BMDL/BMD, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 39(1), 94,1 974
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
OPP Slope Factor
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.04
0.1
0.091
1.22
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
2000
1999
Vol. 41, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
WHODWQ
Health Reference Level (HRL)2 cancer
Y
1
175
20
0.287
Y/N
Y/N
mg/L
ug/L
ug/L
ug/L
EPA, RAISHE, OEHHA, OPP, IARC, CACART
Drinking Water Equivalent Level
Substance Guideline Value; For excess risk of 1 0-5
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,3-Dichloropropene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 240 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
9,164
16,787
15
58
0.16
0.35
0.5
0.2
2.0
39.0
1.0
0.5
1.8
0.99
2.0
39.0
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
34,717,237
0
4,471
# PWSs/Sites/
Samples
12,117
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4
% Samples with
detects
Number of
States
20
0
9
% PWSs/Sites/
Sam pies with
detects
0.03
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.86
Non-cancer: 97.2
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
130
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
2.8
90% of
Detects
92.1
Units for Mag
data
ug/L
Cancer: 0.16
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
pesticide; in organic synthesis (HSDB)
Value
38 days
80.8
2.03
0.00355
2,800
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
1,3-Diisopropyl benzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 241 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Diisopropylbenzene
4042
99627
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.25
3,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - muscle contraction orspasticity,
Behavioral - alteration of classical conditioning, Blood •
changes in erythrocyte (RBC) count
Prevalence Magnitude
5 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year36(9),18,1971
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.58
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,3-Diisopropyl benzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 242 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
38
4.9
2.00E-02
4.33
8
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
1,4-Benzoquinone dioxime
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 243 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,4-Benzoquinone dioxime
4434
105113
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5.94
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1964
Critical Effect
Behavioral - alteration of classical conditioning,
Nutritional and Gross Metabolic - weight loss or
decreased weight gain, Biochemica - Enzyme
inhibition, induction, or change in blood ortissue
levels - true cholinesterase
Prevalence Magnitude
3 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 29(10),15,1964
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol. 29, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
13.9
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1,4-Benzoquinone dioxime
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 244 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rubber additive (HSDB)
Value
1 5 days
1.49
3.74E-10
4,550
29
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1,4-Butanediol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 245 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,4-Butanediol
4866
110634
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.125
400
30
1,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1968
Critical Effect
Reproductive and developmental toxicity
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Biochemical - Metabolism (Intermediary) - other
carbohydrates
Prevalence Magnitude .,,„,-,
9 5 NL-L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No severity information is available; Potency/Severity scored on CTDJPN NOEL.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 33(1), 37,1 968
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,800
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,4-Butanediol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 246 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; humectant, Pharmaceuticals (HSDB)
Value
18
1.30E-09
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
1,4-Butynediol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 247 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,4-Butynediol
4868
110656
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1968
1984
Critical Effect
Blood -changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical -Enzyme
inhibition, induction, or change in blood or tissue
levels -true cholinesterase, Biochemical - Metabolism
(Intermediary) - other carbohydrates
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year33(1),37,1968
Supplemental Data
VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. etal., Chimia,
1 994. Volume(issue)/page/year -, 1 53, 1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4.67
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1,4-Butynediol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 248 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
8.7 days
1
-0.93
1.70E-11
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (PBT)
-------
1,4-Cyclohexanedimethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 249 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,4-Cyclohexanedimethanol
4431
105088
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 7 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/pagefyear
21MAY1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,4-Cyclohexanedimethanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 250 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in films and coatings (HSDB)
Value
15
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1,5,9-Cyclododecatriene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 251 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,5,9-Cyclododecatriene
16316
4904614
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,780
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
Critical Effect
Behavioral -tremor
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0557883
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1,5,9-Cyclododecatriene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 252 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Specialty petrochemical (NLM TOXNET)
Value
15
5.5
4.99E-01
0.39
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
11-Aminoundecanoicacid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 253 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
11-Aminoundecanoic acid
13315
2432997
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
750
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Kidney, Ureter, Bladder -other changes
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-216,1982
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,750
Y/N
Y/N
ug/L
ug/L
IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
11-Aminoundecanoicacid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 254 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer initiator (HSDB)
Value
15
-0.16
1,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
1-Amino-2,4-dibromoanthraquinon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 255 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Amino-2,4-dibromoanthraquinone
2996
81492
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
90
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood - leukemia, Tumorigenic - active as anti-cancer
agent
Prevalence Magnitude
1 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB97-1 1 6636. 104-week rat study.
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
210
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Amino-2,4-dibromoanthraquinon
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 256 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate (HSDB)
Value
60 days
18,000
5.31
1.78E-13
5
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
1-Decanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 257 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Decanol
5018
112301
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4,720
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea
Prevalence Magnitude .,, .,, „
7 3 NL-NL,
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron,
OH 44311) V.19- 1958- Volume(issueypage/year 34,493,1973
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Decanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 258 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; chemica intermediate (HSDB)
Value
7,300
4.57
3.20E-05
37
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
1-Dodecanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 259 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Dodecanol
5039
112538
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,170
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Sandman A.L.
et al,, Ghimia, 1994. Volume(issue)/page/year -,1 19,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Dodecanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 260 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; chemica intermediate; food additive (HSDB)
Value
15,000
5.13
2.22E-05
4
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
1-Heptanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 261 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Heptanol
4965
111706
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Brain and Coverings - other degenerative changes,
Liver - other changes, Kidney, Ureter, Bladder - other
changes
Prevalence Magnitude
3 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -,113,1994
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.058
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
1-Heptanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 262 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent; cosmetic formulations; food additive (HSDB)
Value
74
2.62
1.88E-05
1,670
28
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
1-Hexene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 263 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Hexene
8242
592416
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
Critical Effect
Kidney, ureter, bladder, - changes in tubules including
acute renal failure, acute tubilar necrosis
Prevalence Magnitude
9 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, DCTODJ Drug and Chemical Toxicology. (Marcel Dekker,
270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year23,327,2000<
LOAEL, rat
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,333
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Hexene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 264 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
8.7 days
1,660
3.39
0.41
50
78
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (PBT)
-------
1-Pentanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 265 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Pentanol
2564
71410
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
VCVQK "Vrednie chemichescie veshestva, galogen 1 kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Sandman A.L.
et al., Chimia, 1994. Volume(issue)/page/year -,107,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Pentanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 266 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; synthetic flavor ng agent (HSDB)
Value
4.51
1.51
1.30E-05
22,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
1-Propanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 267 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Propanol
2560
71238
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
600
1,870
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1970
Critical Effect
Endocrine - changes in adrenal weight
Prevalence Magnitude
8 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BIOFX BIOFAX Industrial Bio-Test Laboratories, Inc., Data
Sheets. (1810 Frontage Rd., Northbroolc, IL 60062) Volume(issue)/pagefyear 15-4/1970
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,400
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
1-Propanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 268 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units
Cancer:
Notes
Solvent; chemica intermediate; former pesticide (HSDB)
Value
33
0.25
7.41 E-06
1,000,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2-(Dimethylamino)ethyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 269 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-(Dimethylamino)ethyl acrylate
13333
2439352
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4
455
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Epithelial hyperplasia of the forestomach;
hematological effects; decreased body weight gain.
Lungs, Thorax, or Respiration - other changes
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
rat study; EPASR United States Environmental Protection Agency, Office of Pesticides and Toxic
Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History
unknown. Volume(issue)/paqe/year 8EHQ-1 190-1 1 1 9
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
28
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2-(Dimethylamino)ethyl acrylate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 270 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial Chemical (EPA/SRS)
Value
1 5 days
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2,3-Dibromopropanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 271 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,3-Dibromopropanol
3812
96139
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
681
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
1 7 Li
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/page;year OTS0528372
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
ug/L
ug/L
IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2,3-Dibromopropanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 272 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for flame retardants, insectic des, and pharmaceut cals (HSDB)
Value
15
4
6.30E-08
52,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2,4,5-Trichlorophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 273 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4,5-Trichlorophenol
3800
95954
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
0.003
72
600
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
2000
1972
Critical Effect
Liver & kidney pathology (degenerative changes)
mmune system
Liver - other changes, Liver - changes n liver weight
Prevalence Magnitude .,, .,, „
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; McCollisteret al., 1961. Basis NOEL 100, rat, UF = 1000
Reference Dose
Reference Dose; McCollister et a ., 1961. Basis NOEL/LOEL, rat, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Exon and Koller, 1985. Basis NOAEL, rat.
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; CMSHAF Chemosphere. (Pergamon Press
nc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year
1,153,1972
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2,4,5-Trichlorophenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 274 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
4,689
18,879
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Fungicide, bacter
Value
1,186
3.72
1.62E-06
1,200
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
cde; industrial preservative; chemical intermediate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
2,4,6-Trichlorophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 275 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4,6-Trichlorophenol
3282
88062
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0003
0.003
240
Units
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Increased pups liver weight
mmune system
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol)
Prevalence Magnitude
1 1 NL!
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose; EPA Health Advisory
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Exon and Koller, 1985. Basis NOAEL, rat.
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 9(5), 497, 1990
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
0.3
0.011
0.07
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
WHODWQ
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.01
200
2.1
Y/N
Y/N
mg/L
mg/L
ug/L
ug/L
1994
EPA; RAISHE; OEHHA; IARC; CACART
Drinking Water Equivalent Level
World Health Organization Drinking Water Guideline Value
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2,4,6-Trichlorophenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 276 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
294
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
1,728
1,906
# PWSs/Sites/
Samples
210
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
3
3
% PWSs/Sites/
Sam pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggragate
Notes
Median value of
Detects
90% of Detects
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Fungicide, bactericide; industrial preservative; chem cal intermediate (HSDB)
Value
1,186
3.69
2.59E-06
800
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (HSDB)
-------
2,4-Dimethylphenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 277 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dimethylphenol
4471
105679
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
100
809
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1995
Critical Effect
Clinical signs (lethargy, prostration, ataxia) &
hematological changes
Lethargy, prostration, ataxia, hematological changes
Kidney, Ureter, Bladder - changes in kidney weight
Prevalence Magnitude
8 7 Li
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; U.S. EPA, 1989. Basis NOAEL 50, mouse.
Reference Dose
Reference Dose; U.S. EPA, 1989. Basis NOAEL/LOAEL, mouse, UF = 3000.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TOBHB TAT Toxikologische Bewertung.
Heidelberg, Berufsgenossenschaft der chemischen Industrie Volume(issue)/page/year VI137, 1,1995
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,4-Dimethylphenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 278 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
1,137
168,992
# PWSs/Sites/
Samples
171
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
10
15
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
As a disinfectant/bacteriocide/germicide; chemical intermediate for Pharmaceuticals and pesticides; former insect c de/biocide (HSDB)
Value
718
2.3
9.52E-07
7,870
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2,4-Dinitrophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 279 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dinitropheno
2166
51285
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
10
0.0006
2
49
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1966
Critical Effect
cataract formation in humans
cataract formation
Blood - other changes
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Horner, 1942. Basis LOAEL, human
Reference Dose
Reference Dose; Horner, 1942. Basis LOAEL, human, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve ; oral study in rabbit; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year31(6),3,1966
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
14
Y/N
Y/N
ug/L
ug/L
teratogen
UMD
Drinking Water Equ valent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,4-Dinitrophenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 280 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
294
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
502
649
# PWSs/Sites/
Samples
134
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
3
% PWSs/Sites/
Sam pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum value
of Detects
Year
2004
2004
Maximum value
of Detects
Not Detected
Median value of
Detects
90% of Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of Detects
Not Detected
Units for Mag
data
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermediate; former pestcide (HSDB)
Value
364
1.67
8.61 E-08
2,790
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
2,4-Dinitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 281 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dinitrotoluene
5365
121142
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
0.002
0.002
0.896
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
1998
1985
Critical Effect
Neurotoxicity, hematological, and bilary effects
Neurotoxicity, heinz bodies, and bilary tract hyperplasia
Hematological
Blood - normocytic anemia, Blood - methemoglobinemia-
carboxyhemoglobin, Blood - changes in other cell count
(unspecified)
Prevalence Magnitude , „ ,
1 10 Li L
HRL Ratio(s)
NC HRL/UCMR 90%: 0.042
CAR HRL/UCMR 90%: 0.00015
Notes
Reference Dose
Reference Dose; Ellis et al., 1985 Basis NOAEL 0.2, dog.
Reference Dose
Reference Dose; Ellis et al., 1985 Basis NOAEL, dog. UF = 100
Minimal Risk Level. Ellis etal., 1979, 1985 Basis NOAEL, dog.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 4(4), 257, 1985
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.005
0.68
0.31
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
EPAHA
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
14
0.05
Y/N
Y/N
mg/L
ug/L
ug/L
Repro
CACART; EPA; OEHHA; IARC
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,4-Dinitrotoluene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 282 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621
1
0.028
333
333
333
333
333
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
14
6,702
# PWSs/Sites/
Samples
2,614
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
4
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer: 0.042
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer: 0.00015
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermed ate; in propellants (HSDB)
Value
364
1.98
5.41 E-08
270
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
2,4-Toluenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 283 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Toluenediamine
3790
95807
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Kidney, Ureter, Bladder - other changes, Related to
Chronic Data - death
Prevalence Magnitude
2 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TAEHC Environmental Health Criteria (United
Nations Environment Programme. Geneva, World Health Organization) 1- 1976-
VolumefissueVoaae/vear -.1.1987
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3.2
3.8
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
117
0.0092
Y/N
Y/N
ug/L
ug/L
RAIS; OEHHA; EPA; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,4-Toluenediamine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 284 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
11,834
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in dyes and photographic developers (HSDB)
Value
120
0.14
9.52E-10
74,800
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
2,5-Xylenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 285 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,5-Xylenol
3795
95874
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
383
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1968
Critical Effect
Behavioral - ataxia, Behavioral - muscle contraction or
spasticity, Lungs, Thorax, or Respiration -dyspnea
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-
71. Discontinued. Volume(issue)/page/year33(7-9), 329,1968. Mouse study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,5-Xylenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 286 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Petroleum antiox dant; chemical intermediate (HSDB)
Value
440
2.33
7.10E-06
3,540
29
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2,6-Dimethylphenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 287 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,6-Dimethylphenol
8028
576261
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0006
0.0006
0.6
6
296
Units
mg/kg-d
m g/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1968
Critical Effect
Body weight & blood pressure changes; changes in
protein sulfhydryl groups in blood serum & internal
organs; histopatho ogical changes in liver, kidney &
spleen.
body weight changes, histopathological changes of
internal organs
Liver, kidney, spleen
Liver - other changes, Blood - changes in spleen, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol)
Prevalence Magnitude
8 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Veldre and Janes, 1979. Basis NOEL, rat
Reference Dose
Reference Dose; Veldre and Janes, 1979. Basis NOEL/LOEL, rat, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER; Veldre and Janes, 1979. Basis NOEL/LOEL, rat, UF = 1000
Lowest Observed Adverse Effect Level; oral study in rat; HYSAAV Hygiene and Sanitation (USSR).
English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year 33(7-
9), 329,1968
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4.2
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,6-Dimethylphenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 288 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
733
2.36
6.66E-06
6,050
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
2,6-Xylidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 289 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,6-Xylidine
3258
87627
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
24
221
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Decreased survival and decreased body weights,
deceases in red blood cell count, hemoglobin and
hematocrit positive for cancer in male and female rats
IVIice not tested.
Brain and Coverings - changes in brain weight, Liver -
changes in liver weight, Blood - changes in other cell count
(unspecified)
Prevalence Magnitude .,, „
2 4 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-278,1990
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-
278,1990
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
168
Y/N
Y/N
ug/L
ug/L
CACART; IARC; Note: Tested positive for cancer in male and female rats (NTP)
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2,6-Xylidine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 290 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,938
5,256
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; pesticide (HSDB)
Value
52
1.84
2.50E-06
8,200
35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST - Biodegrades sometimes/recalcitrant (PBT)
-------
2-Chloro-1-propanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 291 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Chloro-1-propanol
2842
78897
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
75
111
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Nutritional and Gross Metabolic - weight loss or decreased
weight gain, Related to Chronic Data - death
Details of toxic effects not reported other than lethal
dose value.
Prevalence Magnitude
9 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; VCVGK "Vrednie chemichescie veshestva,
galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/paqe/year -,185,1994
Supplemental Data
Clayton, QD.( FE. Clayton (eds). Pattys Industrial Hygiene and Toxicology. Volumes 2A, 2B, 2C,
2D, 2E, 2F: Toxicology 4th ed. New York, NY: John Wiley & Sons, Inc., 1993-1 994 p. 2736
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2-Chloro-1-propanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 292 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1986
Maximum
value of
Detects
Year
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
15
2
1.70E-06
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-Ethyl-3-propylacrolein
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 293 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethyl-3-propylacrolein
9266
645625
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
JIHTABJourna of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For
publisher information, see AEHLAU. Volume issue)/page/year 26,269, 1944
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethyl-3-propylacrolein
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 294 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for insecticides and other organics (HSDB)
Value
15
70
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-Ethylhexanal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 295 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexana
5484
123057
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0534445, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethylhexanal
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 296 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; disinfectant (HSDB)
Value
1 5 days
160
0.00076
400
25
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
2-Ethylhexanoic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 297 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexanoic acid
6263
149575
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
61
629
3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
increased liver weight, hepatocyrte hypertrophy
cytoplamic vacuolization
Behavioral - somnolence (general depressed activity),
Liver - changes in liver weight, Skin and Appendages -
hair
Prevalence Magnitude
7 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Publication Juberg, et al., 1998
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0525547
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
427
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethylhexanoic acid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 298 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cosolvent and defoamer in pesticides; chemical intermediate (HSDB)
Value
650
2.64
2.90E-06
1,400
28
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
2-Ethylhexanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 299 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexanol
4405
104767
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
125
100
2,053
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Decreased body weight, increased liver, kidney, stomach
and testes weights, microscopic changes in the liver and
forestomach
Liver - other changes
Prevalence Magnitude
9 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Publication Astill eral, 1996
Lowest Observed Adverse Effect Level; oral study in rat; VCVQK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashieorganicheskie soedinenia". (Hazardous substances.
Halogen and oxygen containing substances), Bandman A.L. et al,, Chimia, 1994.
Volume(issue)/page/year -,116,1994. The LOAEL was used for Potency scoring because it was
lower than the NO(A)EL from other studies.
Supplemental Data
WHO: Environ Health Criteria Number 32: Toxicological Evaluation of Certain Food Additives and
Contaminants. P. 39 (1993)
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
233
Y/N
Y/N
ug/L
ug/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethylhexanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 300 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; plasticizer; wetting agent; dry cleaning (HSDB)
Value
105
2.65E-05
880
2T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2-Ethylhexenal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 301 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexena
29251
26266682
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Behavioral - altered sleep time, chages in motor
activity, muscle contraction and spasticity (including
change in righting reflex)
Prevalence Magnitude .,, „
8 5 NL!'L!
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
QTPZAB, rodent-rat; QTPZAB Qigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992.
For publisher information, see MTPEEI Volume issue)/page/year 32(3),48,1988
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethylhexenal
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 302 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1990
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
1 5 days
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
2-Ethylhexyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 303 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexyl acrylate
4286
103117
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3
4,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme
inhibition, induction, or change in blood ortissue
levels - true cholinesterase
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (V/O MezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year -,16,1 993
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Ethylhexyl acrylate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 304 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
As monomer; in pa nts (HSDB)
Value
15
430
4.09
0.00043
100
ir
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-Ethylhexyl thioglycolate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 305 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexyl thioglycolate
19121
7659861
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
303
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
6 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und
Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955-
Volume(issue)/page/year 20,575,1974)
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Leve
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
2-Ethylhexyl thioglycolate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 306 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of
Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
FRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,E, Half life
KQC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
1997
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Value
15 days
22
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
2-Hydroxyethyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 307 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Hydroxyethyl acrylate
9783
818611
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Sense Organs and Special Senses (Eye) - ptosis,
Behavioral - convulsions or effect on seizure
threshold, Gastrointestinal -alteration in gastric
secretion
Prevalence Magnitude
6 5 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 24(4),56,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Hydroxyethyl acrylate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 308 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
18
-0.21
7.20E-10
39
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
2-Mercaptobenzothiazole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 309 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Mercaptobenzothiazole
6259
149304
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.65
134
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Decreased body weight. Liver toxicity, increased
kidney weight with increased brown pigment.
ncreased incidence of basophilic tubules in the kidney
cortex.
Liver - changes in liver weight
Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
332,1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
4,550
Y/N
Y/N
ug/L
ug/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Mercaptobenzothiazole
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 31 Oof 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
23,624
644,590
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
15
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide; vulcanizer; veterinary medicine (HSDB)
Value
2.41
3.63E-08
120
23
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
2-Methylbutane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 311 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methylbutane
2832
78784
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
357
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Nutritional and Gross Metabolic - weight loss or
decreased weight gain, Related to Chronic Data -
death
Prevalence Magnitude
10 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TIHEEC Toxicology and Industrial Health. (Princeton
Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year
1(3),67,1985
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
833
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Methylbutane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 312 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate; medication (HSDB)
Value
15
520
2.72
1.4
48
55
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-Methylpyridine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 313 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methylpyridine
4741
109068
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0099
674
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood -change in clotting factors, Blood - changes in
other cell count (unspecified), Biochemical - Enzyme
inhibition, induction, or change in blood ortissue
evels - true cholinesterase
Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Behavioral - excitemen
Prevalence Magnitude .,, „
6 5 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Qigiena i Sanitariya. ForEnglish translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volu me(issue)/page/year 33(1 2),1 8,1 968
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 45(12), 62,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.0232
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2-Methylpyridine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 314 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
5
27,839
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
96
1.11
9.96E-06
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2-Napthalenamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 315 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Naphthalenamine
3487
91598
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
1 1 NL!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
1.8
1
mg/L
(mg/kg-d)"1
(mg/kg-d)-'
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.0194
Y/N
Y/N
ug/L
ug/L
OEHHA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Napthalenamine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 316 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
5
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Research chemica ; formerly in dye manufacture (HSDB)
Value
1,000
2.28
8.10E-08
6.4
25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
2-Naphthalenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 317 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Naphthaleno
5876
135193
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
0.437
1,335
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1965
1965
Critical Effect
Decreased motor activity
Brain and Coverings -other degenerative changes,
Behavioral -alteration of classical conditioning
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 3 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/OMezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 30(9),22,1965. The LOAEL was used for potency/severity scoring
because it was lowerthan the NO(A)EL from other studies.
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 30(9), 22,1965
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.02
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Naphthalenol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 318 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
n dyes; as lubricant; former anthe
Value
0.45
2.7
4.60E-08
756
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
mintic (HSDB)
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
2-Nitropropane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 319 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Nitropropane
2889
79469
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased anemia, thrombocyte count, and heart weight
Prevalence Magnitude , „ ,
6 5 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; WHO EHC 130
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
9.5
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol.29, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
117
0.0037
Y/N
Y/N
ug/L
ug/L
Teratogen
CACART; EPA; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Nitropropane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 320 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
294
25,344
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Former pesticide; ndustrial solvent additive; chemica
Value
15 days
24.95
0.93
0.000119
17,000
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
intermediate (HSDB)
Notes
BS = Biodegrades slow (PBT)
-------
2-Propanone oxime
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 321 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Propanone oxime
5638
127060
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
5 7
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Clear evidence of carcinogenicity in male/female rats and male/female mice (NTP)
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Propanone oxime
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 322 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
15 days
0.12
7.80E-06
106,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-Pyrrolidone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 323 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Pyrrolidone
8675
616455
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
80.4
328
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1979
Critical Effect
Behavioral - food intake (animal), Kidney, Ureter,
Bladder -changes in bladder weight, Blood -changes
in serum composition (e.g. TP, bilirubin, cholesterol)
Behavioral - coma, Lungs, Thorax, or Respiration -
dyspnea
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information
Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical
nformation. Volume(issue)/page/yearOTS0521310-3
Supplemental Data
TVLMB8 Trudy Volgogradskogo Gosudarstvennogo Mediteinskogo Instituta. Transactions of the
Volgograd State Medical Institute. (Volgogradsk Gosudarstvennyi Meditskinskii Institut, Volgograd,
USSR) 1 961 - Volume(issue)/page/year 31 , 1 60, 1 979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
187.6
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
2-Pyrrolidone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 324 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in pharmaceutical preparations (HSDB)
Value
1 5 days
17
-0.85
1.06E-09
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
2-tert-Butylhydroquinone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 325 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-tert-Butylhydroquinone
12479
1948330
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.7
0.2
178.6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgfltg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
1997
Critical Effect
Decreased hemoglobin oand/or hematocritand RBC
counts No evidence for cancer in mice or rats No
evidence of cancer in male or female rats or mice
Blood - changes in spleen, Nutritional and Gross Metabolic
- weight loss or decreased weight gain
Prevalence Magnitude
5 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental data; JEFCA and NTP ADI
Maximum Recommended Daily Dose (MRDD); MRDDs were only used for screening, not for attribute
scoring
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
459,1997
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4,900
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
2-tert-Butylhydroquinone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 326 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggragate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Antioxidants in fats and oils (HSDB)
Value
38 days
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
3,3'-Dichlorobenzidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 327 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,3'-Dichlorobenzidine
3511
91941
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
2 1 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.008
0.45
1.2
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1990
1987
Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.08
Y/N
Y/N
ug/L
ug/L
EPA, RAISHE, OEHHA, IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3,3'-Dichlorobenzidine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 328 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
2.01
# PWSs/Sites/
Samples
135
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
0
2
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1M-10M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
n dyes; curing agent for polymers and rubber products (HSDB)
Value
7,489
3.51
5.11E-11
3.1
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
3,3'-Dimethylbenzidine dihydroc
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 329 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,3'-Dimethylbenzidine dihydrochloride
8575
612828
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
200
1.8
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
1991
Critical Effect
Endocrine - changes in thymus weight, Blood - changes in
bone marrow (not otherwise specified), Blood - changes in
erythrocyte (RBC) count
ncreased T3, decreased T4 increased THF, cystic
degeneration and foci of cellular alteration in the liver,
nephropathy, hyperplasia of Zymbals gland preputial
and clitoral glands and alveolar epithelium. Clear
evidence of cancer in male and female mice.
Prevalence Magnitude
1 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
390,1991
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page;year NTP-TR-390,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
4.2
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3,3'-Dimethylbenzidine dihydroc
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 330 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n dyes (NTP)
Value
18
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (HSDB)
-------
3,4-Dichloro-1-butene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 331 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,4-Dichloro-1 -butene
9586
760236
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2
943
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Increased liver weight; increased kidney weight; liver
cell enlargement
Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3,4-Dichloro-1-butene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 332 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
38
2.6
0.0086
420
61
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
3,6-Dichlorosalicylic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 333 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,6-Dichlorosa icylic acid
14832
3401807
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3
660
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1978
1978
Critical Effect
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels -true cholinesterase,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - catalases, Biochemical -
Enzyme inhibition, induction, or change in bl
Brain and Coverings - recordings from specific areas of
CNS
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issueXpage/year43(10),95,1978; 26-week rat study
Supplemental Data
mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
43(10), 95,1978
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3,6-Dichlorosalicylic acid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 334 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (ChemlDPIus)
Value
38 days
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
3-Chloro-2-methyl-1-propene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 335 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Chloro-2-methyl-1-propene
7957
563473
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
214
75
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Related to Chronic Data - death
increased instance of forestomach inflammation; clear
evidence of cancer in rats and mice
Prevalence Magnitude
3 4 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week rat study; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-300,1986
Supplemental Data; NTP Report 209
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.14
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1995
Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
175
0.25
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3-Chloro-2-methyl-1-propene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 336 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
6,635
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
nsecticide/fungic
Value
81
0.0087
1,400
63
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
de (ChemlDPIus)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
3-Methylpyridine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 337 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Methylpyridine
4735
108996
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
1986
Critical Effect
increased latency on evoked potentials, increae
latency of pentylenetetrazol-induged seizures.
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP cites Dyer, et a\., 1 985
rat study; 85JCAE "Prehled PrumysloveToxikolog e; Organicke Latky," Marhold, J., Prague,
Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year -,841,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
233
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3-Methylpyridine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 338 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; chemical intermediate (HSDB)
Value
110
1.2
7.73E-06
1,000,000
45
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
3-Pyridinecarbonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 339 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Pyridinecarbonitrile
4116
100549
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5
1,455
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver cell enlargement or alteration, liver and kidney
weights were increased.
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
3-Pyridinecarbonitrile
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 340 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide; chemical intermediate; former fumigant (HSDB)
Value
38 days
37
0.36
2.74E-07
135,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4,4'-Bipyridine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 341 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Bipyridine
7828
553264
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
172
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral -somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave.,
NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year 10,363,1982. Rat study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
4,4'-Bipyridine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 342 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
38 days
1.28
2.52E-09
4,530
3T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4,4'-Diaminodiphenyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 343 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Diaminodiphenyl ether
4204
101804
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Cardiac - EKG changes not diagnostic of specified effects,
Vascular - BP elevation not characterized in autonomic
section
Prevalence Magnitude
2 2 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-wk rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year51(6),31,1986
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.14
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)1
(mg/kg-d)-1
1987
Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7.9
0.25
Y/N
Y/N
ug/L
ug/L
OEHHA, IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4,4'-Diaminodiphenyl ether
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 344 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
621
985
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
38 days
315
2.06
1.50E-11
35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4,4'-Dichlorodiphenyl sulfone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 345 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Dichlorodiphenyl sulfone
2920
80079
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
ncreased incidence or severity of liver
lesions;cetrilobular hypertrophy, centrilobilar
degeneration and bile diet hyperplasia
Brain and Coverings - recordings from specific areas of
CNS, Liver - liver function tests impaired
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 47(2), 84,1 982
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4,4'-Dichlorodiphenyl sulfone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 346 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; polymer additive (HSDB)
Value
60 days
7,600
3.9
1.40E-07
10
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
4,4'-Methylenebis(N,N-dimethylb
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 347 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4l-Methylenebis(N,N-dimethyl)benzenamine
4189
101611
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.08
0.046
0.046
B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1987
IRIS
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.8
Y/N
Y/N
ug/L
ug/L
RAISHE, EPA, OEHHA, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
4,4'-Methylenebis(N,N-dimethylb
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 348 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for dyes (HSDB)
Value
60 days
14,700
4.37
1.21E-07
4.14
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
4,4'-Methylenedi(phenyl isocyan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 349 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Methylenedi(phenyl isocyanate)
4194
101688
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
zmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year -,63,1 982. Mouse study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1998
1999
Vol., 19, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
4,4'-Methylenedi(phenyl isocyan
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 350 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,fl, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Constituent of adhesives and coat ngs (HSDB)
Value
376,000
5.22
8.96E-07
0.829
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
4-Aminobiphenyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 351 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Aminobiphenyl
3566
92671
Attribute Scores
Potency Severity
8 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
21
1
mg/L
(mg/kg-d)"1
(mg/kg-d)1
(mg/kg-d)-1
1987
Vol. 1, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.00167
Y/N
Y/N
ug/L
ug/L
OEHHA, IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
4-Aminobiphenyl
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 352 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
1
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; research chemical (HSDB)
Value
38 days
857
2.86
1.50E-07
19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4-Aminodiphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 353 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Aminodiphenylamine
4183
101542
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
150
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - food intake (animal), nutritional and gross
metabolic weight loss of decreased weight gain,
related to chronic data - death
Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 lexicologist. (Soc. of Toxicology, Inc., 475 Wolf
Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year 12,103,1992
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
350
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4-Aminodiphenylamine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 354 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye; chemical intermediate for Pharmaceuticals (HSDB)
Value
38 days
3,100
3.70E-10
2T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4-Chloro-1,2-diaminobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 355 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Chloro-1 ,2-diaminobenzene
3792
95830
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.016
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
1987
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
2.19
Y/N
Y/N
ug/L
ug/L
CACART; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4-Chloro-1,2-diaminobenzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 356 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1986
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate and constituent (HSDB)
Value
38 days
1.28
4.99E-10
6,590
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4-Chlorobenzotrichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 357 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Chlorobenzotrichloride
16518
5216251
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude ,
6 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
20
B2
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)"1
ung; adenocarcinoma
USEPA, 1987
USEPA, 1987; mouse study
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.00175
Y/N
Y/N
ug/L
ug/L
EPA; CACART; RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4-Chlorobenzotrichloride
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 358 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
60 days
1,812
4.54
0.000193
4.04
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
4-Hydroxy-4-methyl-2-pentanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 359 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Hydroxy-4-methyl-2-pentanone
5511
123422
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
40
2,520
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Functional and histopatological effects in the kidney
Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis)
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
8 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day rat study; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0557741
Supplemental Data
rat study; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0557732
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4-Hydroxy-4-methyl-2-pentanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 360 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
21
-0.098
4.24E-09
1,000,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
4-Methyl-2-pentanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 361 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Methyl-2-pentanol
4665
108112
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Most likely CMS effects based on inhalation data
Prevalence Magnitude ,,, 0 , „
8 5 NL' L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
American Conference of Governmental Industrial Hygienists. Documentation of the Threshold
Limit Values and Biological Exposure Indices. 5th ed. Cincinnati, OH: American Conference of
Governmental Industrial Hygienists, 1986., p. 401
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
4-Methyl-2-pentanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 362 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; in lubricants and lacquers (HSDB)
Value
143
1.43
16,400
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
4-Methyl-3-thiosemicarbazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 363 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Methyl-3-th iosem icarbazide
18177
6610293
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
14
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral -tremor, Gastrointestina -changes in
structure orfunction of salivary glands,
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude , „
57 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0571100
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
4-Methyl-3-thiosemicarbazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 364 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
1 5 days
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
4-tert-Butylcyclohexanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 365 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-tert-Butylcyc ohexanone
3968
98533
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1975
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
9 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. Forpublisher
information, see FGTOD7. Volume(issue)/page/year 13,729,1975
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
4-tert-Butylcyclohexanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 366 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
38 days
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
4-Vinylcyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 367 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Vinylcyclohexene
4103
100403
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
500
200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Inflamatory lesions and epithelial hyperplasia of the
forestomach, cytologic alteration of the adrenal cortex •
clear evidence of ovarian cancer in female mice and
increased incicence of adrenal adenomas - mortality
too high to make judgment on male and female
Prevalence Magnitude ,,, _
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year
PB91211250
Supplemental Data; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly
U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year PB9121 1250
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1994
Vol. 60; cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
467
Y/N
Y/N
ug/L
ug/L
IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
4-Vinylcyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 368 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; polymer intermediate (HSDB)
Value
3,300
3.93
0.045
50
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
5-Chloro-o-toluidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 369 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Chloro-o-toluidine
3789
95794
Attribute Scores
Potency Severity
5 9
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
464
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1973
Critical Effect
Details of toxic effects not reported other than lethal
dose value
3-model Categorical Prediction
L?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NCILB Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer
Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year NCI-E-C-72-3252,1973
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
2000
Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
5-Chloro-o-toluidine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 370 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate; in dye formulations (HSDB)
Value
38 days
234
2.58
26
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
5-Ethylidene-2-norbornene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 371 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Ethylidene-2-norbornene
25357
16219753
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Hematological effects
Prevalence Magnitude ,,, _
6 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data; CTDJPN; male
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
28
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
5-Ethylidene-2-norbornene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 372 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
900
0.13
58
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
5-Nitro-o-anisidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 373 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Nitro-o-anisidine
4039
99592
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Liver - liver function tests impaired, Liver - changes in liver
weight, Blood - other changes
Prevalence Magnitude , „
1 8 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day rat study; GTPZAB Gigiena Truda i Professional'nye
Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year
32(3), 48,1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.046
0.049
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
1987
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,050
0.714
Y/N
Y/N
ug/L
ug/L
RAISHE, OEHHA, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
5-Nitro-o-anisidine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 374 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate (HSDB)
Value
38
37.53
1.47
1.47E-08
115
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
5-Nitro-o-toluidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 375 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Nitro-o-toluidine
4036
99558
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.033
C
3
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)-1
1990
1990
iver
Vol. 48; mouse study; USEPA 1987
USEPA1987
Vol. 48
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1.06
Y/N
Y/N
ug/L
ug/L
RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
5-Nitro-o-toluidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 376 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
255
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate (HSDB)
Value
38 days
85.4
1.87
1.94E-08
1,878
26
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodergades slow with acclimation (PBT)
-------
Abamectin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 377 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Abamectin
61779
71751412
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
1.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1997
2001
Critical Effect
Embryo- and fetotoxicity: increased mortality, reduced
weight. Maternal toxicity: reduced body weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
9 3 Li
HRL Ratio(s)
NC HRL/SWC EEC: 57.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat study; HBPTO Handbook of pesticide toxico ogy. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year2,1160,2001
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Abamectin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 378 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
# Sam pies
Amount
Released
14,932
9
9.3
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
24
1
2
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 0.244 ug/L
Non-cancer: 57.4
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Ground water chronic: 0.00371 ug/L
Cancer:
Pesticide; anthelm ntic (HSDB)
Value
5,000
1.70E-07
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (HSDB)
-------
Acetaminophen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 379 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetaminophen
4349
103902
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
EMEAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
747
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cholestatic effects
Liver - other changes, Kidney, Ureter, Bladder - changes
in bladder weight, Nutritional and Gross Metabolic - weight
oss or decreased weight gain
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification
495
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
mg/kg-d
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
350
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude ,,, _
10 5 NL'
HRL Ratio(s)
NC HRL/NREC SW MAX: 35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; The European Union European Medicines Agency (EIVIEA)
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-394,1992
Supplemental Data
Tumorigenic Dose - 50
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetaminophen
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 380 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Focazio, etal., 2008
HRL Ratios (HRL/NREC SW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
84
Amount
Released
# PWSs/Sites/
Samples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
23.8
Number of
States
% PWSs/Sites/
Samples with
detects
0
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer: 35
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
10
Year
Maximum
value of
Detects
Not detected
0.16
0.11
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not detected
90% of
Detects
Not detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Focazio, etal., 2008. Sci.Tot. Env., 402(2-3), pp. 201-216.
Cancer:
Pharmaceutical
Value
15
41
0.46
6.42E-13
14,000
38
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow
-------
Acetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 381 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetic acid
2464
64197
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1.47
3,310
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1972
1959
Critical Effect
Gastrointestinal - changes in structure orfunction of
esophagus, Gastrointestinal - ulceration or bleeding
from small intestine, Gastrointestinal - ulceration or
bleeding from large intestine
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AIHAAP American Industrial Hygiene Association Journal.
(AIHA,475Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year
33,624,1972. Human study
Supplemental Data
rat study; DMDJAP Delaware State Medical Journal. (Wilmington, DE) V.1-32(1), 1929-60. For
publisher information, see DSMJAA. Volume(issue)/page/year 31,276,1959
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3.43
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetic acid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 382 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; veterinary medicine; chemical reagent (HSDB)
Value
6.5-228
-0.71
1,000,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Acetic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 383 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetic anhydride
4676
108247
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,780
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1951
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
10 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10,
1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year4,119,1951; rat study
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 384 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; chemica reagent (HSDB)
Value
4.4 minutes
120,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Acetone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 385 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetone
2510
67641
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.9
0.9
2
100
3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2003
2003
1994
Critical Effect
Nephrotoxicity
Nephropathy
Hemato.
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - normocytic anemia
Prevalence Magnitude
9 7 Li
HRL Ratio(s)
NC HRL/NAWQA 90% : 568
Notes
Reference Dose
Reference Dose; rat study; UF = 1000, MF = 1; Dietz, et., al, 1991; NTP, 1991
Reference Dose
Reference Dose
Minimal Risk Level, UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NIH-91-3122
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
6,300
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 386 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,605
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
653
168
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
25
6.45
% Samples with
detects
Number of
States
% PWSs/Sites/
Sam pies with
detects
3.83
0.3
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
2
Non-cancer: 568
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1,806
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
210
2.77
Median value of
Detects
11.1
90% of
Detects
52.4
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
11
90% of
Detects
114
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Solvent; in PPCPs (HSDB)
Value
1.98
-0.24
3.96E-05
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Acetone cyanohydrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 387 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetone cyanohydrin
2688
75865
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0008
14.8
1.90
Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1971
1994
Critical Effect
increased relative weight; liver
Gastrointestinal - ulceration or bleeding from stomach,
Liver - other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
4 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; UF = 3,000; Rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 35-wk rat study; AMPMAR Archives des Maladies
Professionnelles de Medecine du Travail etde Securite Sociale. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.7- 1946- Volume(issue)/page/year 32,653,1971
Supplemental Data
Mouse study; TOVEFN Toksikologicheskii Vestn k. (18-20 Vadkovskii per. Moscow, 101479, Russia)
History Unknown Volume(issue)/page/year (1), 29,1994
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5.6
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetone cyanohydrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 388 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
106,961
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
4
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; (HSDB)
Value
1
-0.03
1.30E-05
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
Acetonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 389 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetonitrile
2621
75058
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.006
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood- decreased hematocrit; Liver- increased relative
weight; hepatic lesions; erythrocyes- decreased cell
count
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
42
Y/N
Y/N
ug/L
ug/L
Teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acetonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 390 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
11,220
12,784,367
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
14
30
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; in PPCPs; chemical intermediate (HSDB)
Value
4.5
-0.34
3.45E-05
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
Acrylic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 391 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acrylic acid
2862
79107
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
0.5
0.135
250
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1983
Critical Effect
Reduced pup weight
iver
Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in bladder weight, Related to Chronic Data - changes in
testicular weight
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose. BASF, 1993. Rat study
Reference Dose
BASF, 1993. rat study, uf=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270
Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year 6,1,1983; oral study in rat
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol. 19, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3,500
Y/N
Y/N
ug/L
ug/L
Teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acrylic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 392 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
19,798
6,817,569
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
9
30
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical and polymer intermediate (HSDB)
Value
1.201
0.35
3.69E-07
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF/BST
Notes
BF = Biodegrades fast (BIODEG); BST = Biodegrades somet mes/recalcitrant (BIODEG)
-------
Acrylonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 393 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acrylonitrile
4592
107131
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.04
2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1984
Critical Effect
decreased sperm counts
Hemato.; decreased red cell counts
Endocrine - adrenal cortex hyperplasia, Endocrine -
changes in adrenal weight, Blood - other changes
Prevalence Magnitude
1 1
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve ; Biodynamics, 1980b. Rat study; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons
Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year
4, 1 31 , 1 984; 60-day rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.006
0.54
1
B1
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1990
1999
Biodynamics, 1980a,b; Quastetal., 1980a; rat study
OEHHA lists IARC classification of 2B
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
7
0.06
Y/N
Y/N
ug/L
ug/L
Teratogen list
EPA, RAISHE, OEHHA, IARC, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Acrylonitrile
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 394 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,614
# Sam pies
Amount
Released
21,559
7,925,644
# PWSs/Sites/
Samples
180
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
% Samples with
detects
Number of
States
10
29
% PWSs/Sites/
Samples with
detects
0
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
> 1B
> 1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Not Detected
Not Detected
Median value of
Detects
Not Detected
90% of Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide/fumigant; polymer intermediate (HSDB)
Value
8.3
0.25
0.000138
74,500
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Adipic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 395 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Adipic acid
5549
124049
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4,000
800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
gastrointestinal effects: hypermotility, diarrhea and weight
ow or decreased we ght gain
Chronic inflamatory alterations of the intestines
Prevalence Magnitude ,,, ,,, _
10 5 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAO Nutrition Meeting Reports 401 1 1 967
Supplemental Data; FDA/Informatics. NTIS PB230 305
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,867
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Adipic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 396 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; in PPCPs; polymer intermediate (HSDB)
Value
26
0.08
4.70E-12
14,000-30,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Adiponitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 397 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Adiponitrile
4964
111693
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
22
22
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1996
1984
Critical Effect
Maternal toxicity
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data. Journal. Johannsen et al 1986
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Sax's Dangerous Properties of Industr al Materials. 9th ed. Volumes 1-3. New York, NY: Van
Nostrand Reinhold, 1996., p. 73. Rabbit study.
rabbit study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
49(12), 40,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Adiponitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 398 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical and polymer intermediate (HSDB)
Value
16
-0.32
1.21E-09
80,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Aldrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 399 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aldrin
6511
309002
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00003
0.00003
0.00003
0.00003
0.0001
0.0001
0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1992
2000
1994
2000
1966
Critical Effect
iver lesions, increased liver to body weight ratio
iver
iver
Endocrine - other changes, Blood - other changes
Prevalence Magnitude , „
1 6 L'
HRL Ratio(s)
CAR HRL/NCOD R2 90% : 4.55
Notes
Reference Dose
Reference Dose; Fitzhugh et al., 1964; Basis LOAEL 0.025, rat, UF=1000.
Reference Dose
Reference Dose
Minimal Risk Level; Fitzhugh et a ., 1964; Basis LOAEL 0.025; rat study; UF = 1,000
Acceptable Daily Intake; combined total for aldrin and dieldrin
Acceptable Daily Intake
Tolerable Daily Intake; Fitzhugh and Nelson, 1963; Fitzhugh etal., 1964; Basis LOAEL 0.025; rat study,
dog study; UF = 250
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year31(4),13,1966; 26-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
17
17
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1992
1992
1987
Vol. 5, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.21
0.002
Y/N
Y/N
ug/L
ug/L
Teratogen
EPA, RAISHE, OEHHA, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Aldrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 400 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,221
12
0.0982
0.1
4.4
0.84
4.4
4.4
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
2,961
# PWSs/Sites/
Samples
5,226
105
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
32
% Samples with
detects
Number of
States
1
4
% PWSs/Sites/
Sam pies with
detects
0.61
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.01
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
107
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99
90% of
Detects
102
Units for Mag
data
ug/L
ug/L
Cancer: 4.55
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
2002
Former insecticide (HSDB)
Value
106,000
6.5
4.40E-05
0.017
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (HSDB)
-------
alpha-Chlorohydrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 401 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Chlorohydrin
3823
96242
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
5
26
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
2000
1994
1982
Critical Effect
Reproductive - Paternal Effects - spermatogenesis (incl.
genetic material, sperm morphology, motility, and count),
Reproductive - Fertility - other measures of fertility
Reproductive - Paternal Effects (sperm motility and
count)
Behavioral - somnolence (general depressed activity),
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude , „
5 7 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; rat study. REPTED Reproductive Toxicology. (Pergamon Press
nc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year
15,11,2000
Supplemental Data; Reproductive Toxicology Volume 8, Issue 3, May^June 1994, Pages 237-250
rat study; IPCLBZ International Pest Control. (McDonald Pub., 238A High St., Uxbridge, Middx., UK) V.5-
1962- Volume(issue)/page/year 24,20,1982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
11.7
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
alpha-Chlorohydrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 402 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; chemical intermediate (HSDB)
Value
1 5 days
1
6.10E-08
1,000,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
alpha-Methylbenzenemethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 403 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Methylbenzenemethanol
3990
98851
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
375
1,071
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1990
Critical Effect
Decreased body weight gain, impaierd renal function,
early mortality CancerPositive male rat and female
mouse, negative female rat and male mouse
Liver - changes in liver weight, Related to Chronic Data -
death
Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue);pagefyear NTP-TR-369,1990
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-369,1990; 13-wk rat
study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,625
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
alpha-Methylbenzenemethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 404 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
Units
Ibs/yr
Ibs/yr
Year
1994
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flavoring agent; n PPCPs; laboratory reagent (HSDB)
Value
<5-52
2.90E-07
1,950
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
alpha-Methylstyrene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 405 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Methylstyrene
3989
98839
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
o.or
1,000
50
4,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1990
1963
Critical Effect
increased weight, liver
reproductive/developmental
Kidney, Ureter, Bladder - proteinuria, Blood - changes in
eukocyte (WBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; rat study; UF = 1 ,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGH "Vrednie chemichescie veshestva, galogenproisvodnie
uglevodorodov". (Hazardous substances Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.
Volume(issue)/page/year -,203,1990; 4-wk rat study
Supplemental Data
mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
28(12), 14,1963
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
490
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
alpha-Methylstyrene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 406 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC> Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Polymer intermec
Value
817.2
3.48
0.00254
89
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate; UV degradaton inhibitor (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
Ametryn
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 407 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ametryn
9881
834128
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.072
0.009
0.009
0.009
25
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1988
1987
2001
Critical Effect
Liver toxicity. Degenerative & inflam matory liver
effects
iver toxicity
iver
Nutritional and Gross Metabolic - weight loss or decreased
weight gain; Blood - other changes
Prevalence Magnitude ,,, _
6 6 NL'
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose; Supplemental Data; OPP. Ciba-Geigy, 1961a
Reference Dose; Ciba-Geigy, 1961 a. rat study; Basis NOEL 8.6 mg/kg-d; UF = 1,000
Reference Dose
Reference Dose; Ciba-Geigy, 1961 a. rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; HBPTO Handbook of pesticide toxicology. Robert Krieger ed,
Academic press, 2001 Volume(issue)/page/year 2,1 51 4,2001 ; 2-yr rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
504
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ametryn
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 408 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
445,571
31
409
# PWSs/Sites/
Samples
75
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
5
3
5
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
445
2.98
2.39E-09
209
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (HSDB)
-------
Amitraz
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 409 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Amitraz
32124
3308961 1
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0125
0.0025
0.0025
0.01
100
Units
mg(kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
1998
1978
Critical Effect
Hypothermia, drowsiness, decreased blood pressure &
heart rate
blood sugar increase, hypothermia
increased mean blood sugar concentration
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, _
9 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Upjohn Co., 1972a; Basis NOEL = 0.25 mg/kg-d; Dog study; UF = 100
Reference Dose
Reference Dose; Upjohn 1973; UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Dog study - SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd.,
College Park, MD 20740) Volume(issue)/page/year 78-1,22,1978
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
87.5
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Amitraz
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 41 Oof 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
137,097
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
17
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide; veter nary medication (HSDB)
Value
38
644,000
5.5
9.89E-06
1
7
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Ammonia
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 411 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonia
19125
7664417
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6.18
0.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/L
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
2006
Critical Effect
Gastrointestinal - other changes
Taste threshold
Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/DBP ICR MED: 150
Notes
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; DDSCDJ Digestive Diseases and Sciences. (Plenum Pub. Corp.,
233 Spring St., New York, NY 1001 3) V.24- 1979- Volume(issue)/page/year 36,33,1991; 4-wk rat study
Lowest Observed Effect Level. EPA: 2006 Edition of the Drinking Water Standards and Health
Advisories. EPA 822-R-06-01 3. Note: Taste threshold of 30 mg/L converted to a dose using 2 L/d
drinking water intake and 70 kg body weight.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1992
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
30,000
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
HRL set at taste threshold of 30 mg/L
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ammonia
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 412 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF IOR
# PWSs/Sites
sampled
68
#with Detects
58
% PWSs/Sites
with detects
85.29
Minimum value of
Detects
Maximum
value of
Detects
1,100
Median value of
Detects
200
Mean value of
Detects
262
Units for Mag
data
ug/L
Ambient Water Occurrence Data
# PWSs/Sites sampled
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
8,185
# Sam pies
Amount
Released
6,284,889
172,424,459
n
PWSs/Sites/Sa
mples
535
% PWSs/Sites
with detects
5,907
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
171
Minimum value
of Detects
72.2
% Samples with
detects
Number of
States
50
54
%
PWSs/Sites/Sam
pies with
detects
32
Maximum value of
Detects
2
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
10
Non-cancer: 150
Amount Range
>10M-50M
>500M - 1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value
of Detects
34,000
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
15,000
90% of Detects
43
Median value of
Detects
99% of
Detects
284
90% of
Detects
Units for Mag
data
2,400
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Notes
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Measured as N
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
231
99% of
Detects
1,291
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermediate; defoliant; antifungal agent for produce (HSDB)
Value
14.3
-1.38
3.45E-06
3,740
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Ammonium carbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 413 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonium carbamate
10601
1111780
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
681
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea, Skin and
Appendages - hair
Prevalence Magnitude , „
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issueXpage;yearOTSOS35595; rat study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ammonium carbamate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 414 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in fertilizers (HSDB)
Value
1 5 days
-3.67
very soluble
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Ammonium thiosulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 415 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonium thiosulfate
19349
7783188
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,098
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7
ncomplete data for scoring HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 1 13095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 26(6),54,1982. Guinea pig study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ammonium thiosulfate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 416 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50-100M
>50-1QOM
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide; defoliant; in PPCPs (HSDB)
Value
very soluble
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Aniline hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 417 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aniline hydrochloride
6119
142041
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1 NOTE: SK 61 19 s the salt of ani ine (SK 2438)
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
Critical Effect
Endocrine - changes in spleen weight, Blood -
methemoglobinemia-carboxyhemoglobin, Blood -
changes in erythrocyte (RBC) count
Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AECTCV Archives of Environmental Contam ination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issue)/page;year 24,368,1993. 90-day rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
46.7
Y/N
Y/N
ug/L
ug/L
Teratogen list
CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Aniline hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 418 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer and chemcal intermediate; in PPCPs, in inks (HSDB)
Value
1 5 days
44-489
0.9
2.02E-06
36,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
Environmental fate parameters are for the free base, not the hydrochloride salt.
-------
Anisole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 419 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Anisole
4127
100663
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.65
2,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1946
Critical Effect
Endocrine - other changes
Behavioral - tremor, Behavioral - convulsions or effect on
seizure threshold, Behavioral - excitement
Prevalence Magnitude ,,, _
3 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVQK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page7year -,290,1994. 26-
wk rabbit study
Supplemental Data
mouse study; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins
Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 88,400,1946
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.517
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Anisole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 420 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flavoring agent; n PPCPs; chem cal intermediate (HSDB)
Value
35
2.11
0.00435
1,520
31
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Aspirin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 421 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aspirin
2149
50782
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0021
66.7
200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2002
1969
Critical Effect
Lungs, Thorax, or Respiration -tumors
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
1 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BJCAAI British Journal of Cancer. (Macmillan Press Ltd.,
Houndmills, Basingstoke, Hants. RQ21 2XS, UK) V.1- 1947- Volume(issue)/page/year 87,49,2002.
24-wk female human study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
rat study; 34ZIAG "Toxicology of Drugs and Chemcals," Deichmann, W.B., New York, Academic Press,
nc., 1969 Volume(issue)/page/year-,67,1969
Cancer Data - no quantitative risk estimate for the cancer effect was identified
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.005
Y/N
Y/N
ug/L
ug/L
Teratogen list
CACART, UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Aspirin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 422 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Medication (HSDB)
Value
5.4-6.3 days
42-106
1.19
1.30E-09
4,600
33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Auramine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 423 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Auramine
7200
492808
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.168
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme
inhibition, induction, or change in blood or tissue
levels - catalases
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad,
Russia) V.1-145, 1949-82. Discontinued. Volume(issue)/page/year 105,45,1974. 17-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.88
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1987
Vol. 1, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.392
Y/N
Y/N
ug/L
ug/L
OEHHA, CACART, IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Auramine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 424 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n dye manufacture; medication; fungicide; antiseptic (HSDB)
Value
65-74 days
2,000
3.5
8.05E-08
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DST
Notes
Degrades sometimes/recalcitrant (HSDB)
-------
Azinphos-methyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 425 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Azinphos-methyl
3200
86500
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00149
0.005
0.91
Units
mgflsg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
1997
Critical Effect
RBC ChE inhibition, increased incidence of diarrhea
Brain and Coverings - other degeneratve changes, Blood -
other changes, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - true cholinesterase
Prevalence Magnitude
8 3 NLi
HRL Ratio(s)
NC HRL/NAWQA 90% : 68.9
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, seeTOSCF2
Volume(issue)/page/year35,101,1997; 1 3-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
Y
10.4
0.2
Y/N
Y/N
ug/L
ug/L
mg/L
UMD
Drinking Water Equivalent Level
Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Azinphos-methyl
EPA-OGWDW
August 2009
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,103
# Sam pies
Amount
Released
2,091,014
# PWSs/Sites/
Samples
283
669
12
145
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
# of detects
8
5
0
2.04
% Samples with
detects
Number of
States
42
% PWSs/Sites/
Samples with
detects
2.5
2.2
0
0.002
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.012
0.012
Non-cancer: 68.9
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
3.37
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.021
0.253
0.144
0.114
0.027
Median value of
Detects
0.151
90% of
Detects
0.932
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
National Aggragate
Notes
Median value of
Detects
95th % lie
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) raw water data
Pesticide Pilot Mentoring Program (USGS/EPA) finished water data
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Insecticide (HSDB)
Value
27.9 days
487-4,644
2.75
2.40E-08
20.9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DS
Notes
DS = Degrades slow (HSDB)
-------
Bentazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 427 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bentazon
28242
25057890
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.03
0.03
0.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998
1999
1989
1998
Critical Effect
Blood loss into the gastrointestinal tract; Coagulation
defect in male & female dogs, Circu atory system .
blood loss in gastrointestinall tract; coagulation defect
Prevalence Magnitude ,,, _
9 4 NL'
HRL Ratio(s)
NC HRL/NAWQA 90% : 276
Notes
Reference Dose
Reference Dose; Allen et al., 1 989. Dog study; UF = 100, Basis NOAEL 3.2 mg/kg-d
Reference Dose
Reference Dose; UF = 100; dog study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
E
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1998
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHO DWQ
210
300
Y/N
Y/N
ug/L
ug/L
ug/L
Drinking Water Equivalent Level
World Health Organization Drink ng Water Guide
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bentazon
EPA-OGWDW
August 2009
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,540
# Sam pies
Amount
Released
7,749,130
# PWSs/Sites/
Samples
100
186
n
PWSs/Sites/Sa
mples
5,583
197
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
# of detects
1
14
80
21
n of detects
2
4.339
% Samples with
detects
Number of
States
45
% PWSs/Sites/
Samples with
detects
1
7.5
25.6
9.3
%
PWSs/Sites/Sam
pies with
detects
0.04
0.002
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0188
0.002
Minimum value of
Detects
0.23
Non-cancer: 276
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
11.5
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.0188
0.018
0.344
0.019
Maximum
value of
Detects
6.2
0.1
Median value of
Detects
0.76
90% of
Detects
4.79
99% of Detects
Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
Units for Mag No(es
data
ug/L National Aggregate
ug/L National Aggregate
Notes
Median value of
Detects
Median value of
Detects
3.11
95th % lie
value of
Detects
0.021
0.019
90th % lie
value of
Detects
5.58
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2002
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) raw water
Pesticide Pilot Mentoring Program (USGS/EPA) finished water
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former herbicide (HSDB)
Value
6.7-50 days
37.5
2.34
2.18E-09
500
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (HSDB)
-------
Benzaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 429 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzaldehyde
4114
100527
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
17.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1994
Critical Effect
Forestomach hyperplasia & lesions, kidney toxicity
renal tubular necrosis). Gl tract, Kidney
forestomach, kidney; lesions, toxicity
Lungs, Thorax, or Respiration - other changes, Liver -
multiple effects
Prevalence Magnitude .,, „
6 7 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Kluwe et al., 1 983; rat study; UF = 1 ,000; Basis NOEL 200 mg/kg-d
Reference Dose
Reference Dose; rat study; Kluwe, 1983; UF = 1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Sandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,396,1994; 5-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Benzaldehyde
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 430 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; chemical intermediate (HSDB)
Value
32.7
1.48
2.67E-05
6,570
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Benzidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 431 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzidine
3586
92875
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.003
2.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
brain, liver
brain, liver; cell vacuo izations, call alterations
Prevalence Magnitude , „
3 1 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Littlefield etal., 1983; mouse study
Reference Dose
Reference Dose; Littlefield etal., 1983; mouse study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.00002
230
500
A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1987
IRIS
Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
21
0.0002
Y/N
Y/N
ug/L
ug/L
EPA; RAIS; OEHHA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Benzidine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 432 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
66.61
82.92
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye manufacture; chemical intermediate (HSDB)
Value
2,740
1.34
7.05E-11
322
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Benzofuran
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 433 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzofuran
6383
271896
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
Critical Effect
Nephropathy (males) chronic inflamation, ulcers and
epitheliam hyperplasia of the stomach Clear evicence
of cancer in male and female mice, some evidence in
female rats, no evidence in male rats
Prevalence Magnitude
1 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 3-wk rat study
Supplemental Data; NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/pagefyear NTP-TR-370,1 989
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1995
Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
Y/N
Y/N
ug/L
ug/L
IARC, CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Benzofuran
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 434 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n resin manufacture (HSDB)
Value
1 5 days
680
2.67
0.00053
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Benzoic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 435 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzoic acid
2484
65850
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4
4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
No adverse effects observed. Decreased Potency
Score by one integer
Prevalence Magnitude ,,,
87 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; FDA, 1973; human study; Basis NOAEL 34 mg/kg-d; UF = 1
Reference Dose
Reference Dose; FDA, 1973; human study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
1989
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
28,000
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Benzoic acid
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 436 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
FRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,E, Half life
Koc, Organic Carbon Partition Coefficient
og Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1DOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; food preservative; chemical intermediate (HSDB)
Value
0.2-3.6 days
14.49
1.87
3.82E-08
3,400
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Benzotriazole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 437 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzotriazole
3739
95147
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.599
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
Endocrine - other changes, Blood - normocytic
anemia, Blood - leukopenia
Prevalence Magnitude
57 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(1 1 ),70,1 981 ; 26-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.4
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Benzotriazole
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 438 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Photographic chemical; chemical ntermediate; plastics stabilizer; corrosion nhibitor (HSDB)
Value
145
1.44
3.17E-07
19,800
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (BIODEG)
-------
Benzotrichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 439 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzotrichloride
3933
98077
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Liver - other changes, Liver - changes n liver weight,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - hepatic microsomal mixed oxidase
(dealkylation, hydroxylation, etc.)
Prevalence Magnitude
42 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Sandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,43,1994; 28-day rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0003
13
B2
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1990
ung
IRIS
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.07
0.003
Y/N
Y/N
ug/L
ug/L
CACART; EPA; RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Benzotrichloride
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 440 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
745
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
4
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1,180
3.9
0.000259
21.7
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Benzyl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 441 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzyl alcohol
4113
100516
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
143
5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
Critical Effect
Epithelial hyperplasia, forestomach
Brain and Coverings - other degeneratve changes,
Related to Chronic Data - death
Prevalence Magnitude .,, „
6 7 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NTP, 1988. rat study; UF = 1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-343,1989; 13-wk rat
study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,100
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Benzyl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 442 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
15.7
1.1
3.38E-07
42,900
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast(BIODEG)
-------
Bis(2-chloro-1-methylethyl) eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 443 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-ch loro-1 -m ethylethyl) ether
4702
108601
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
2 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
12.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
Critical Effect
Blood - changes in leukocyte (WBC) count, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
Enzymes
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 50(5), 69,1985; 26-wk rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
o.or
c
3
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)"1
1999
Vol. 41, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
30.1
0.5
Y/N
Y/N
ug/L
ug/L
CACART; RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bis(2-chloro-1-methylethyl) eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 444 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
883
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent; medication (HSDB)
Value
39.2
2.48
0.000113
1,700
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Bis(2-chloroethyl) ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 445 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-chloroethyl) ether
4939
111444
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
26
25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1981
Critical Effect
Brain and Coverings - other degeneratve changes, Liver -
multiple effects, Kidney, Ureter, Bladder - other changes
Decreased body weight
Prevalence Magnitude
4 2 Li
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Bandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,283,1994; 45 day oral study
n rat
ATSDR; Weisburger, etal., 1981. Journal of the National Cancer Institute, 67: 75-88.
Cancer Data
EPA Lifetime Cancer Risk, 104
ATSDR Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.003
0.3
1.1
2.5
B2
3
mg/L
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1988
1999
IRIS
ATSDR
Vol. 9, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
60.67
0.03
Y/N
Y/N
ug/L
ug/L
EPA; RAISHE; OEHHA; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bis(2-chloroethyl) ether
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 446 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2
478
# PWSs/Sites/
Samples
2,348
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
4
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; chemical intermediate; solvent; gasoline additive (HSDB)
Value
14.95
1.29
1.70E-05
17,200
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA/BS/BST
Notes
BFA = Biodegrades fast with acclimat on; BS = Biodegrades slow; BST = B odegrades sometimes/recalcitrant (BIODEG)
-------
Bis(2-ethylhexyl) sodium sulfos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 447 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-ethylhexyl) sodium sulfosuccinate
8032
577117
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
5
1,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1943
1962
Critical Effect
Behavioral -food intake (animal), Gastrointestinal -
hypermotility, diarrhea, Related to Chronic Data - death
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 3 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JIHTAB Journal of Industrial Hygiene and Toxicology.
(Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year 25,175,1943; 24 wk rabbit study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
Rat study; JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1 995
Broadway, Suite 1701, New York, NY 10023) V.1- 1947- Volume(issue)/page/year 13,469,1962
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.17
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bis(2-ethylhexyl) sodium sulfos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 448 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; in PPCPs; medical on (HSDB)
Value
9.37-1,041
5.00E-12
71,000
22
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Bis(chloromethyl) ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 449 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(chloromethyl) ether
7727
542881
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude , „
1 1 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.000016
220
46
A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1991
1987
ung
IRIS
Vol. 4, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.00016
Y/N
Y/N
ug/L
ug/L
EPA; RAISHE; OEHHA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bis(chloromethyl) ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 450 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Laboratory reagent; in polymer manufacture (HSDB)
Value
4.395
0.58
0.000206
22,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Bisphenol A
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 451 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bisphenol A (4,4'-lsopropylidenediphenol)
2918
80057
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.05
2.5
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Reduced body weight
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
350
Y/N
Y/N
ug/L
ug/L
Prevalence Magnitude
10 5 NLi
HRL Ratio(s)
NC HRL/NREC NA SW MED: 1,750
Notes
Reference Dose
Reference Dose; Basis = LOAEL 50 mgflsg-d; UF = 1,000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat
Supplemental Data
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bisphenol A
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 452 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal.,2002
Stackelberg, etal., 2007
Stackelberg, etal., 2007
Focazio, etal., 2008
HRL Ratios (HRL/NREC NA SW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
85
# Sam pies
Amount
Released
3,538
1,504,711
# PWSs/Sites/
Samples
73
35
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
7
41.2
% Samples with
detects
21.07
10.78
Number of
States
8
27
% PWSs/Sites/
Samples with
detects
41.2
17
67
9.6
Minimum value of
Detects
Units
States
States
States
Maximum value of
Detects
12
0.22
0.36
1.9
Non-cancer: 1,750
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
0.14
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
0.2
0.2
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Notes
Surface water monitoring; Kolpin, eta., 2002. Env. Sci. &Technol., 36(6), pp. 1202-1211.
New Jersey Finished Drinking Water; Stackelberg, etal., 2007. Sci. Tot. Environ., 377(2-3), pp. 255-272.
New Jersey Surface Water; Stackelberg, et al., 2007. Sci. Tot. Environ., 377(2-3), pp. 255-272.
NREC II Raw Drinking Water; Focazio, et al., 2008. Sci.Tot. Env., 402(2-3), pp. 201-216.
Cancer:
Production of polycarbonate and epoxy resins. Formely used as fungicide. (HSDB)
Value
75,200
3.32
9.2E-12
120
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA-BST
Notes
BFA = Biodegrades fast with acclimat on; BST = Biodegrades sometimes/recalcitrant
-------
BMX-1
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 453 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-1 (3-Chloro-4-(bromochloromethyl)-5-
hydroxy-2(5H)-furanone)
78954
132059519
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
HM
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 1
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; HM = High to medium probability of be ng carcinogenic
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
BMX-1
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 454 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites/
Samples with
detects
44
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.17
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.01
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Finished drinking water monitoring; Krasner, era./, 2006. Env. Sci.
Technol. , 40(23), pp 7175-7185 (and related documentation).
Disinfection By-Product
Value
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
BMX-2
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 455 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-2 (3-Chloro-4-(dibromomethyl)-5-hydroxy-
2(5H)-furanone
74966
132059520
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
HM
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 1
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; HM = High to medium probability of be ng carcinogenic
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
BMX-2
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 456 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites/
Sam pies with
detects
33
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.03
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
ND
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci.
Technol., 40(23), pp 7175-7185 (and related documentation).
Disinfection By-Product
Value
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
BMX-3
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 457 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-3 (3-Bromo-4-(dibromomethyl)-5-hydroxy-
2(5H)-furanone
78951
132059531
Attribute Scores
Potency Severity
Prevalence Magnitude
10 1
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
HM
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
ug/L
ug/L
3-model Categorical Prediction
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; HM = High to medium probability of be ng carcinogenic
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
BMX-3
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 458 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% PWSs/Sites/
Samples with
detects
11
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
0.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
ND
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci.
Technol., 40(23), pp 7175-7185 (and related documentation).
Disinfection By-Product
Value
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Boron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 459 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Boron
18864
7440428
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.09
0.09
0.01
31
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
1970
Critical Effect
Decreased fetal weight (developmental)
Atrophy and spermatigenetic arrest
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - dehydrogenases, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
transferases
Prevalence Magnitude
10 10
HRL Ratio(s)
NCHRL/NIRS90%:2.95
Notes
Reference Dose
Reference Dose; Price etal., 1996a; Heindel etal., 1992
Reference Dose
Reference Dose; Basis = NOAEL/LEL, MF = 1, UF= 100, dog, testicle (Weir & Fisher, 1972)
Minimal Risk Level - Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rabbit; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(1 1 ) , 1 1 , 1 970
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ
CADW MAC
3
1,400
0.5
5
Y/N
Y/N
mg/L
ug/L
ug/L
mg/L
mg/L
1992
Drinking Water Equivalent Level
World Health Organization Drink ng Water Guide
Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Boron
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 460 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
810
81.9
5
3,950
46.8
475
2,585
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
9,360
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4,841
% Samples with
detects
Number of
States
% PWSs/Sites/
Sam pies with
detects
51.7
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.01
Non-cancer: 2.95
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
800,800
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
180
90% of
Detects
730
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; oxygen scavenger; catalyst; in composite structural mater als (HSDB)
Value
14.3
0.23
0.0245
43,700
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
Bromacil
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 461 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromacil
6526
314409
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
62.5
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1970
Critical Effect
Decreased body weight gain
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
NC HRL/NAWQA 90% : 206
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(1 1 ) , 1 1 , 1 970
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
5
700
Y/N
Y/N
mg/L
ug/L
ug/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Bromacil
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 462 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,555
# Sam pies
Amount
Released
614,219
0
0
# PWSs/Sites/
Samples
100
197
# PWSs/Sites/
Samples
7,392
108
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
2
49
#with Detects
3
2.37
% Samples with
detects
15.2
0.61
Number of
States
4
0
0
% PWSs/Sites/
Sam pies with
detects
0
0
0.9
15.7
% PWSs/Sites/
Samples with
detects
0.04
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
0.93
Non-cancer: 206
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
57
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.481
0.481
Maximum
value of
Detects
4
0.245
Median value of
Detects
0.675
0.57
3.4
90% of
Detects
25.9
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Median value of
Detects
1.5
95% of
Detects
0.081
90% of
Detects
3.18
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) finished water data
Pesticide Pilot Mentoring Program (USGS/EPA) ambient water data
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
64-275 days
2.3-289
2.11
1.29E-10
815
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Bromine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 463 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromine
19194
7726956
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
440
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issueXpage/year 39(4),86,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Bromine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 464 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
5
381,257
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
15
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n water disinfect on; flame retardant; chemical intermediate; in dyes; med cation (HSDB)
Value
33,600
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Bromobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 465 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromobenzene
4724
108861
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver lesions
3-model Categorical Prediction
NL?
HRL Ratio(s)
NC HRL/NCOD R1 90%: 21.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bromobenzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 466 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
16,450
24,125
32
31
0.195
0.128
0.04
0.05
40
4.69
1
0.5
6.55
3
40
4.69
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,878
3
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
0.07
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
0.03
0.009
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Non-cancer: 21.4
Amount Range
>500K-1M
>500K-1M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.4
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
83
0.012
Median value of
Detects
0.4
90% of
Detects
0.4
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.74
90% of
Detects
66.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
n organic synthesis; as solvent (HSDB)
Value
268
2.99
0.00269
446
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Bromochloroacetonitrile (SCAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 467 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bromochloroacetonitrile (BCAN)
66739
83463621
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
3
M
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
ug/L
ug/L
Prevalence Magnitude
10 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; M = Medium probability of being carcinogenic
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bromochloroacetonitrile (SCAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 468 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF ICR finished water
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
62.5
Mean value of
Detects
1.63
Maximum
value of
Detects
13.4
Median value of
Detects
1.29
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# Sam pies
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% Samples w/
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
Notes
Cancer:
Disinfection By-Product
Value
38
13
0.38
1.20E-06
18,700
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze
-------
Bromoethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 469 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromoethane
2612
74964
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
WHO LD50
Value
1,350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mgJkg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
3 7 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
WHO CICAD 42 2002, LD50 1350 mg/kg/day
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
ug/L
ug/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Bromoethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 470 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent; refrigerant; fumigant; medication (HSDB)
Value
40 days
179
1.61
0.00741
9,000
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DSA
Notes
DSA = Degrades s ow with acclimation
-------
Butanenitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 471 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butanenitrile
4791
109740
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
28
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
1996
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
3 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, RJ. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 609
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Butanenitrile
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 472 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
15 days
46
0.53
5.23E-05
33,000
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Butyl benzyl phthalate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 473 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyl benzyl phthalate
3168
85687
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.2
0.2
1.3
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
1998
2000
Critical Effect
Significantly increased liver-to-body weight & liver-to-
brain weight ratios
Significantly increased liver-to-body weight & liver-to-brain
weight ratios
Gastrointestinal - changes in structure or function of
salivary glands, Kidney, Ureter, Bladder - changes in
kidney weight; endocrine - other changes
Prevalence Magnitude
7 3 NL
HRL Ratio(s)
NC HRL/CAL DHS 90%: 23.7
Notes
Reference Dose
Reference Dose; NTP, 1985; Basis NOAEL 159 mg/kg/day, rat, UF=1000, pancreas (NTP, 1985)
Reference Dose
Reference Dose; NTP, 1985; Basis NOAEL/LEL, rat, liver, brain, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis = BMD 132 mg/kd/day, UF = 100, rat (Hammond et al 1987)
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; REPTED Reproductive Toxicology. (Pergamon
Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year
14,513,2000
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1988
Vol. 73, 1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
1,400
Y/N
Y/N
mg/L
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Butyl benzyl phthalate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 474 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
851
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
24
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
2.82
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.004
Non-cancer: 23.7
Amount Range
100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
124
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.2
90% of
Detects
59
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermed ate; plasticizer (HSDB)
Value
9,359
4.73
1.26E-06
2.69
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Butyric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 475 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyric acid
4649
107926
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
8,790
2,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
8 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Budavari, S. (ed.). 1989. The Merck Index - Encycopedia of Chemicals, Drugs and Biologicals. Rahway,
NJ: Merck and Co., Inc., p. 243.
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1 982
Volume(issue)/page/year -,30,1 982
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Butyric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 476 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; food additve; varnish manufacture (HSDB)
Value
64
0.79
5.35E-07
60,000
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Butyric anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 477 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyric anhydride
4521
106310
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
8,790
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
8 7 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issueypage/year -,321, 1986; Ratstudy
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Butyric anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 478 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
1.39
0.000111
4,560
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
C.I. Acid Red 114, disodium sal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 479 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Acid Red 114, disodium salt
18026
6459945
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
8
120
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Decreased body weight gain shortened lifespan at
higher doses. Clear evidence of carcinogenicity in
male and female rats (mice not tested)
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
transaminases
Prevalence Magnitude
1 10 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP Report 405
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
405,1991
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Vol.57, 1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
56
Y/N
Y/N
ug/L
ug/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
C.I. Acid Red 114, disodium sal
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 480 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Textile dye (HSDB)
Value
180
7.86
5.05E-31
2.50E-06
54
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades slow/recalcitrant (PBT)
-------
C.I. Direct Blue 15
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 481 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Direct Blue 15
13296
2429745
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
45
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
22 month study: decreased surviva
Prevalence Magnitude , „
37 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/pagefyear NTP-TR-397,1992
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
105
Y/N
Y/N
ug/L
ug/L
EPA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
C.I. Direct Blue 15
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 482 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
K0c« Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Notes
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye; biological stain (HSDB)
Value
136,000,000
0.71
8.56E-44
0.0059
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
C.I. Direct Blue 218
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 483 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Direct Blue 21 8
30455
28407376
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
40
500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1994
Critical Effect
Squamous and basal hyperplasia of the forestomach -
clear evidence of cancer in male and female mice,
some evidence in male rats and no evidence in female
rats
Liver - other changes, Kidney, Ureter, Bladder - changes
in bladder weight, Blood - pigmented or nucleated red
blood cells
Prevalence Magnitude ,,,
23 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-430,1994
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-
430,1994
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
280
Y/N
Y/N
ug/L
ug/L
CACART; clear evidence of cancer in male and female mice, some evidence in male rats and no
evidence in female rats (NTP)
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
C.I. Direct Blue 218
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 484 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
2,609
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 140
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Textile dye (HSDB)
Value
180
54
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades slow/recalcitrant (PBT)
-------
C.I. Disperse Yellow 3
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 485 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Disperse Yellow 3
13973
2832408
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Decreased weight gain throughout the study; a dose
related increase in renal pigmentation was observed in
the females- Cancer was positive for male rats and
female mice and negative for female rats and male
mice
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTIS National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year NTP-
TR-222,1982
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Vol. 48, 1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
933
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
C.I. Disperse Yellow 3
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 486 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2002
2002
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Textile dye (HSDB)
Value
60
3.98
1.50E-11
1.18
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades slow/recalcitrant (PBT)
-------
C.I. Pigment Red 53, barium sal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 487 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Pigment Red 53, barium salt (2:1)
16485
5160021
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
5
ncomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Haematological effects; spleen, kidney, and liver
effects- unspecified.
3-model Categorical Prediction
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; SIDS
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.005
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Vol.57, 1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
58.3
Y/N
Y/N
ug/L
ug/L
CACART; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
C.I. Pigment Red 53, barium sal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 488 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in paints and inks (HSDB)
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
C.I. Solvent Yellow 14
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 489 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Solvent Yellow 14
9896
842079
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cardiac valve fibrosis. Nephropathy, Atrophy of
pancreatic acinus
Prevalence Magnitude ,,, _
1 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; Study Report TR-226
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Vol. 8, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
46.7
Y/N
Y/N
ug/L
ug/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
C.I. Solvent Yellow 14
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 490 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye for organic so utions (HSDB)
Value
38
5.51
2.62E-11
0.674
5
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades with acclimation (PBT)
-------
Calcium carbonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 491 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium carbonate
7087
471341
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
60,000
6,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1972
Critical Effect
Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 7 NL
HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.36
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; EPASR United States Environmental Protection Agency,
Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
Washington, DC 20460) History unknown. Volume(issue)/page/year#86940001000,1994
Supplemental Data
28ZPAK"SbornikVysledkuToxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., InstitutPro
Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
Volume(issue)/page/year -, 267, 1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140,000
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Calcium carbonate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 492 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,848
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
11,811
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
99.7
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
100
Non-cancer: 0.36
Amount Range
>10M-50M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
426,000,000
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
158,000
90% of
Detects
389,000
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Antacid; food additive; pesticide; chemical intermed ate (HSDB)
Value
In sol.
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Calcium hydroxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 493 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium hydroxide
11051
1305620
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
7,300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
1981
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 10
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1 -1 1, Yushima, Bunkyo-ku, Tokyo, Japan) V.1-
1950- Volumefissuej/page/year 32,1477,1981
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Calcium hydroxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 494 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; lubricant; veterinary medication; chemical intermediate (HSDB)
Value
1,730
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/reca citrant
-------
Calcium octadecanoate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 495 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium octadecanoate
11834
1592230
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgfltg
Date
1992
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 36(4),17,1992
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Calcium octadecanoate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 496 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer stabilizer; food additive; waterproofing (HSDB)
Value
38
40
2
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Caprolactam
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 497 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Caprolactam
4466
105602
Attribute Scores
Potency Severity
3 7
Prevalence Magnitude
10 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
0.5
482
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Reduced offspring body weight
Reduced offspring body weight
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Serotta etal., 1984
Basis NOAEL 50 mgflsgWay, rat, UF=100
Reference Dose
Reference Dose; Serotta et al., 1984; Basis NOAEL/LOAEL, rat, UF=100, MF = 1
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0555505
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
4
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Vol. 39, Suppl. 7; Vol. 71; 1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3,500
Y/N
Y/N
ug/L
ug/L
Teratogen
IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
Caprolactam
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 498 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
KOC. Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n polymer synthes s (HSDB)
Value
57.4
0.66
2.52E-08
772,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Carbaryl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 499 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbaryl
2448
63252
Attribute Scores
Potency Severity
3 8
Prevalence Magnitude
1 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
0.1
0.01
0.1
0.008
0.23
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
2006
1975
Critical Effect
Plasma & brain ChE inhibition. Q1* 0.000875 (mg/kg-day)-
1 - Likely.
Kidney; liver
mmunological Includ ng Allergic - decrease in humoral
immune response
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
NCHRL/NCODR290%:70
CAR HRL/NCOD R2 90% : 40
Notes
Reference Dose
Reference Dose; Carpenter et a ., 1961; Basis NOAEL9.6 mg/kg/day, rat, UF=100, kidney & liver
Reference Dose
Reference Dose; Carpenter et a ., 1961; Basis NOAEL/LOAEL, rat, UF=100, kidney & liver
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; ora
Pharmacology. (Academic Press, Inc., 1 E.
Volume(issue)/paqe/year32,587,1975
study in rabbit; TXAPA9 Toxicology and Applied
First St., Duluth, MN 55802) V.1- 1959-
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.000875
Likely to be
carcinogenic in
humans
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mgflsg-d)-1
2003
2007
incidence of hemangiosarcomas in mice
2002 and 2007 Carbaryl Occupational Risk Assessment in August 2008 Amended RED
2003 and 2007 Carbaryl Occupational Risk Assessment in August 2008 Amended RED
Vol. 12, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
Y
0.4
70
40
0.09
Y/N
Y/N
mg/L
ug/L
ug/L
mg/L
2006
Teratogen
EPA; IARC
UMD
Drinking Water Equivalent Level
Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Carbaryl
EPA-OGWDW
August 2009
CCL 3 Contaminant Information Sheet Page 500 of 1 124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,679
13
0.103
0.18
3
0.18
1
3
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratio (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,142
85
# Sam pies
85
Amount
Released
4,857,542
25
3,475
# PWSs/Sites/
Samples
0.296
0.550
4,671
697
14
#with Detects
14
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
0
1
9.76
16.5
% Samples with
detects
17
0.12
Number of
States
48
3
7
% PWSs/Sites/
Samples with
detects
0.9
0
0.02
0.0005
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
3.5
Non-cancer: 70
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
33.5
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.041
Not Detected
3.5
0.0167
0.04
Median value of
Detects
0.17
0.9
0.138
90% of
Detects
1.2
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
3.5
90% of
Detects
3.5
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer: 40
Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) 2001 (GCMS)
Pesticide Pilot Mentoring Program (USGS/EPA) 9060 (HPLC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Insecticide; veter nary medication (HSDB)
Value
38
242
2.36
4.36E-09
110
18
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation
-------
Carbendazim
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 501 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbendazim
21347
10605217
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.588
2,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
1989
1991
Critical Effect
Liver effects: hepatic cirrhosis, swollen, vacuolated
hepatic cells, & mild chronic hepatitis
Brain and Coverings - other degeneratve changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TXCYAC Toxicology. (Elsevier Scientific Pub.
reland, Ltd., POB85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year 57,173,1989
Supplemental Data
Dog; PEMNDP Pesticide Manua . (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath
CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,123,1991
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Carbendazim
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 502 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide (HSDB)
Value
>35days
350
2.10E-11
33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DS
Notes
DS = Degrades slow (HSDB)
-------
Carbon disulfide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 503 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbon disulfide
2629
75150
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
139
1,200
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1966
Critical Effect
Fetal toxicity/malformations
Fetal toxicity/malformations
Cardiac - changes in heart weight, Endocrine -
hyperglycemia, Immunological Including Allergic -
decrease in cellular immune response
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude .,, „
10 3 NL!'L!
HRL Ratio(s)
NC HRL/NAWQA 90%: 5,426
Notes
Reference Dose
Reference Dose; Basis NOEL = 1 1 mg/kg-d, rabbit, oral, UF = 1 00 (Hardin et al., 1 981 )
Reference Dose
Reference Dose; Basis NOEL, MF= 1, UF = 100, rabbit (Hardin et al., 1981)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rabbit; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 31 (1 ), 1 3, 1 966
Supplemental Data
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki,
213 Japan) V.1- 1963- Volume(issue)/page/year 32,145,1994
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
700
Y/N
Y/N
ug/L
ug/L
Developmental (male & female); Teratogen
CACART; UMD
CACART; UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Carbon disulfide
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 504 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,606
# Sam pies
Amount
Released
6,902
26,946,784
# PWSs/Sites/
Samples
1,075
606
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4
23.3
% Samples with
detects
Number of
States
11
32
% PWSs/Sites/
Samples with
detects
0.37
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.55
Non-cancer: 5,426
Amount Range
>100-500M
>10-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
34
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
34
0.02
Median value of
Detects
0.129
90% of
Detects
3.4
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
14.4
90% of
Detects
29.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former insecticide/fumigant; rubber additive; industria solvent; chemical intermediate (HSDB)
Value
1
1.94
0.0144
1,180
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS =Biodegrades s ow (BIODEG)
-------
Catechol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 505 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Catechol
5350
120809
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
65
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Blood -changes in serum composition (e.g. TP,
bilirubin, cholesterol) IARC say that it causes
hyperplacia of the fore stomach and pyloric mucosa
which is consistent with the cancer response but does
not identify the study or dose.
Prevalence Magnitude ,,, _
10 6 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JTPAE7 Journal of Toxicologic Pathology. (Nihon
Dokusei Byori Gakkai, editor, 3-25-8 Nfshi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988
Volume(issue)/page/y ear 29,180,2001
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
152
Y/N
Y/N
ug/L
ug/L
IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Catechol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 506 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
26,494
35,91 1
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
25
30
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical antiox dant; chemical intermediate for insecticides and PPCPs (HSDB)
Value
118
0.88
1.20E-09
461,000
37
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
CFC-11
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 507 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
CFC-1 1
2673
75694
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
0.3
0.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Survival & histopathology. Increased mortality,
incidence of pleuritis & pericalditis
Survival & histopathoogy
Prevalence Magnitude , „ ,
8 7 Li L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 247
Notes
Reference Dose
Reference Dose; Basis LOAEL = 488 mg/kg-d, Adjusted Basis LOAEL = 349 mg/kg-d, UF = 1 000,
rat, oral (NCI, 1978)
Reference Dose
Reference Dose; Basis LOAEL, MF = 1, UF = 1000, rat& mouse (NCI, 1978)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
10
2,100
Y/N
Y/N
mg/L
ug/L
ug/L
EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
CFC-11
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 508 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
16,851
23,341
249
265
1.48
1.14
0.01
0.0014
1,444
105
1.3
0.85
8.5
5
72
24.9
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,340
# Sam pies
Amount
Released
54
266,643
# PWSs/Sites/
Samples
12,179
104
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
51
2.4
% Samples with
detects
Number of
States
3
13
% PWSs/Sites/
Sam pies with
detects
0.42
0.007
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Non-cancer: 247
Amount Range
100M-500M
50M-100M
Units
Ibs/yr
Ibs/yr
Year
1990
1994
24
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
46
0.143
Median value of
Detects
1.1
90% of
Detects
17
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1.8
90% of
Detects
13.4
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; chemical intermediate; in fire extinguishers; in insulation blowing; in aerosols - major uses now phased out (HSDB); gas
Value
48.6
2.53
0.0971
1,100
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
CFG-12
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 509 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
CFC-12
2674
75718
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.2
0.2
14
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Reduced body weight
Reduced body weight
Behavioral - alteration of classical conditioning, Blood -
changes in erythrocyte (RBC) count, Bochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - true cholinesterase
Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 77.8
Notes
Reference Dose
Reference Dose; Basis NOAEL = 15 mg/kg-d, rat, UF = 100, oral (Sherman, 1974)
Reference Dose
Reference Dose; Basis NOAEL/LOAEL, MF = 1, UF = 100, rat, whole body (Sherman, 1974)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 52(3), 73,1 987
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5
1,400
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
CFG-12
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 51 Oof 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
16,076
22,145
221
285
1.37
1.29
0.1
0.1
405
230
2
1.22
18
8
200
27.7
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,341
# Sam pies
Amount
Released
10
224,225
n
PWSs/Sites/Sa
mples
12,205
108
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
271
2.49
% Samples with
detects
Number of
States
2
15
/O
PWSs/Sites/Sam
pies with
detects
2.22
0.01
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Non-cancer: 77.8
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1990
1994
38
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
160
0.2
Median value of
Detects
0.6
90% of
Detects
4.3
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
2.4
90% of
Detects
6.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; n insulation blowing; in aerosols - major uses now phased out (HSDB); gas
Value
38 days
48.6
2.16
0.343
280
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Chloral Hydrate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 511 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chloral Hydrate
6463
302170
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
1
Units
mg/kg-d
mg/Kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
Critical Effect
CNS depression and Gl irritation
Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification
106
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
mg/kg-d
1995
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
mg/L
W/L
W/L
Prevalence Magnitude
10 8 Li
HRL Ratio(s)
NCHRL/DBPICR90%: 58.3
Notes
Reference Dose
Reference Dose; basis LOAEL - 10.7 mg/kg-d, UF = 100, oral human study; Goodman and Oilman,
1985.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Supplemental Data
Tumorigenic Dose - 50
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chloral Hydrate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 512 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
# PWSs/Sites
sampled
10,911
#with Detects
7,913
% PWSs/Sites
with detects
72.5
Mean value of
Detects
5.47
Maximum
value of
Detects
92.2
Median value of
Detects
4
90% of
Detects
12
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, etal., 2006
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
75
Units
States
States
States
Minimum value of
Detects
Non-cancer: 58.3
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
16
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
90% of
Detects
Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et a/, 2006. Env.Sc/.
Techno!. , 40, pp 71 75-71 85 (and related documentation).
Cancer:
Sedative; hypnotc; in organic synthesis (HSDB)
Value
38
82
0.99
5.71 E-09
793,000
41
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Chlorendicacid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 513 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorendic acid
5103
115286
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.091
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
1990
Vol. 48
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.385
Y/N
Y/N
W/L
W/L
CACART; IARC; OEHHA
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorendicacid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 514 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame retardant in textiles and building materials (HSDB)
Value
180 days
49
2.3
3.00E-14
6
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Chlorethoxyfos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 515 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorethoxyfos
36627
54593838
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0006
0.0495
2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
1996
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Plasma, RBC, and/or Brain ChE inhibition
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - true cholinesterase
Behavioral - somnolence (general depressed activity),
Behavioral - food intake (animal), Gastrointestinal -
changes in structure or function of salivary glands
Prevalence Magnitude , „
7 5 L'
HRL Ratio(s)
NC HRL/SW Chronic EEC: 52.5
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
TOXID9Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
Volume(issue)/page/year30,124,1996
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0536238
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4.2
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorethoxyfos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 516 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
252,792
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
10
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
Surface water chronic: 0.08 ug/L
Non-cancer: 52.5
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 0.002 ug/L
Cancer:
nsecticide (HSDB)
Value
4.3-59 days
890
4.20E-06
5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DST
Notes
DST = Degrades sometimes/recalcitrant (HSDB)
-------
Ch loroacetaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 517 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chloroacetaldehyde
4598
107200
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
36.1
LM
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
mg/kg-d
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
W/L
W/L
Prevalence Magnitude
10 5
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Tumorigenic Dose - 50
DSSTOX; LM = Low to medium probability of being carcinogenic
DSSTOX
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ch loroacetaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 518 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Krasner, et al.
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
50
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
2.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0,2
90% of
Detects
Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, eta/, 2006. Env. Sci.
Technol. , 40, pp 7175-7185 (and related documentation).
Cancer:
Disinfection By-Product
Value
15
39
0.39
2.39E-05
111,000
45
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades Slow
-------
Chloroacetyl chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 519 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroacetyl chloride
2856
79049
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Supplemental Lowest Oral LD50
Value
208
207
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Weakness and collapse; effects on ungs liver and
gastrointestinal tract on necropsy
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat (American Conference of Governmental Industril Hygeinists, Inc. Documentation of the Threshold
Limit Values and Biological Exposure Indices. 6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH, 1991., p.
OPPTS; Monsanto study 1992 OST0536760
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
14.5
Y/N
Y/N
W/L
W/L
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Chloroacetyl chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 520 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,fl, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; tear gas (HSDB)
Value
4
-0.22
0.00023
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Chlorobenzilate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 521 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorobenzilate
7384
510156
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
0.02
35.3
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
1980
1972
Critical Effect
Decreased food intake, weight gain, stool quantity, and
hyperirritablility
mmunological Includ ng Allergic - decrease in cellular
immune response
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Basis NOEL = 5 mg/kg-d, rabbit, oral (Ciba-Geigy, 1984a)
Reference Dose
Reference Dose; Basis NOEL/LEL, MF = 1, UF = 300, rabbit (Ciba-Geigy Corp., 1984)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 17-week oral study in rat; FATOAO Farmakologiya i
Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya
Kniga, 1 1 3095 Moscow, USSR) V.2- 1939- Vo ume(issue)/page/year 35(3), 352,1972
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.27
0.11
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1987
Vol. 30, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
140
0.318
Y/N
Y/N
W/L
W/L
CACART; IARC; OEHHA; RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorobenzilate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 522 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
5
n
PWSs/Sites/Sa
mples
117
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
0
1
%
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide (HSDB)
Value
1,263
4.74
7.24E-08
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Chloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 523 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroethane
2616
75003
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
4 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol. 52, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
CACART; Equivocal evidence of carcinogenicity in male and female rats; clear evidence in female mice;
nadequate study in male mice (NTP).
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chloroethane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 524 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
20,236
24,433
78
84
0.385
0.344
0.10
0
112
288
1.00
1.30
9.7
6.85
64
84.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,271
# Sam pies
Amount
Released
586
732,853
n
PWSs/Sites/Sa
mples
11,930
39
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
44
0.913
% Samples with
detects
Number of
States
5
15
%
PWSs/Sites/Sam
pies with
detects
0.37
0.0175
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
40
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
46
0.06
Median value of
Detects
1
90% of
Detects
40
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1.3
90% of
Detects
2.3
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermed ate; solvent; refrigerant; medication (HSDB); gas
Value
23.7
1.43
0.0111
6.71
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Chloromethyl methyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 525 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloromethyl methyl ether
4605
107302
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2A
A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
1988
Oral
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.0146
Y/N
Y/N
W/L
W/L
EPA; UMD; IARC;OEHHA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chloromethyl methyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 526 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
1,085
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
2.38
0.32
0.000303
69,400
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Chlorophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 527 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorophenol
28429
25167800
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
0.003
570
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
Critical Effect
Reproductive effects - Ortho isomer
mmune system- Rat
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
66 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis NOAEL = 0.3 mg/kg-d, rat, UF = 100, oral (Exon and Koller, 1985)
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat, oral; BSLIB Biochemistry Section, Laboratory Investigations Branch, DRDS, ALOSH, NIOSH
Volume(issue)/page/year -,1,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 528 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
76
43,439
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; disinfectant; veterinary med cation (HSDB - uses for 2-chloropheno , 3-chlorophenol and 4-chlorophenol)
Value
15 days
2.16
4.15E-07
28,500
29
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Chloropicrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 529 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloropicrin
2704
76062
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
32
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1965
Critical Effect
Gastrointestinal - other changes, Blood - changes in
serum composition (e.g. TP, bilirubin, cholesterol),
Nutritional and Gross Metabolic - weight loss or
decreased weight gain
Prevalence Magnitude
10 6 NLi
HRL Ratio(s)
NC HRL/DBP ICR 90% : 93.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; (DCTODJ Drug and Chemical Toxicology. (Marcel Dekker,
270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year 17,125,1994)
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
74.7
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chloropicrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 530 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR
# PWSs/Sites
sampled
10,905
#with Detects
2,837
% PWSs/Sites
with detects
26.02
Mean value of
Detects
1
Maximum
value of
Detects
13.6
Median value of
Detects
0.8
90% of
Detects
1.61
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Supplemental Water Data
Krasner, et al.
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
13,882,188
0
14,865
n
PWSs/Sites/Sa
mples
4
# PWSs/Sites
sampled
12
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
#with Detects
6
% Samples with
detects
Number of
States
29
0
8
%
PWSs/Sites/Sam
pies with
detects
25
% PWSs/Sites
with detects
50
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5
Minimum value of
Detects
Non-cancer: 93.4
Amount Range
1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
1.5
Maximum
value of
Detects
2
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
Median value of
Detects
0.2
99% of
Detects
1.4
75% of
Detects
0.4
Units for Mag
data
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Techno!. , 40, pp 71 75-71 85 (and related documentation).
Rodenticide; fumgant; tear gas (HSDB)
Value
81
2.09
0.00205
1,621
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Chloroprene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 531 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroprene
5636
126998
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1980
Critical Effect
Alopecia
Liver - changes in liver weight, Endocrine - changes in
spleen weight, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - dehydrogenases
Prevalence Magnitude ,,, „
3 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL, MF = 1 , hair, rat, UF = 1 00 (USEPA, 1 989).
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 45(2), 17,1 980
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
140
Y/N
Y/N
W/L
W/L
CACART; IARC
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chloroprene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 532 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
74
925,010
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in adhesives (HSDB)
Value
15 days
67.7
2.53
0.056
875
74
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Chlorothalonil
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 533 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorothalonil
12375
1897456
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.015
0.015
0.015
0.03
1.5
75
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1994
1990
Critical Effect
Increased kidney weights & hyperplasia of the
proximal convoluted tubules in the kidneys, ulcers &
forestomach hyperplasia. Q1 * 0.00766 (mg/kg-day)-1 .
Group B2. See CAR
Renal tubular epithel al vacuolation
Tubular epithelial vacuolation
Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Kidney, Ureter,
Bladder - changes in bladder weight
Prevalence Magnitude ,,, „
4 4
HRL Ratio(s)
NCHRL/NAWQA90%: 342
CAR HRL/NAWQA 90% : 3.66
Notes
Reference Dose
Reference Dose; Basis NOEL =1.5 mg/kg/day, UF = 100, kidney, dog, oral (Diamod Shamrock Chemical,
1970a)
Reference Dose
Reference Dose; Basis NOEL/LEL, MF = 1, kidney, dog, UF = 100 (Diamod Shamrock Chemical, 1970)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; OPP RfD
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
53,155,1990
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
EPA Lifetime Cancer Risk, 1CT5
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.15
0.5
0.011
0.0031
0.00766
B2
2B
mg/L
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1999
Corresponds with OPP slope factor.
OPP
Vol. 73, 1999; note: OEHHA lists lARCs cancer class as 3.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.5
140
1.5
Y/N
Y/N
mg/L
W/L
W/L
CACART; IARC; EPA; OEHHA; RAIS
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Chlorothalonil
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 534 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,547
# Sam pies
Amount
Released
11,916,713
6
303,181
n
PWSs/Sites/Sa
mples
4,099
29
15
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
0
0.33
% Samples with
detects
Number of
States
48
2
7
%
PWSs/Sites/Sam
pies with
detects
0
0.007
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
Non-cancer: 342
Amount Range
Fungicide; bacter
Value
2,392
3.05
2.00E-06
0.6
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.71
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
0.05
Median value of
Detects
0.41
90% of
Detects
0.71
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
90% of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer: 3.66
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide Data Program (USDA)
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient (HPLC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) Finished (HPLC/MS)
ocide (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cinnamaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 535 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cinnamaldehyde
4388
104552
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
550
0.208
1,160
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
Critical Effect
Slight decrease in body weight
Liver - changes in liver weight, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
hepatic microsomal mixed oxidase (dealkylation,
hydroxylation, etc.), Related to Chronic Data - death
Behavioral - coma
Prevalence Magnitude ,,,
5 7 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal; Bickers, et al. Food and Chemical Toxicology 43 (2005) 799-836
Lowest Observed Adverse Effect Level; 24-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 49,306,1992
Supplemental Data
FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information,
see FCTOD7. Volume(issue)/page/year 2,327,1964
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3,850
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cinnamaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 536 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; attractant in insect control (HSDB)
Value
1 5 days
0.19
1,420
33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Citric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 537 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Citric acid
2776
77929
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
620
3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - other transferases, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol)
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
85 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD); MRDDs were only used for screening,
not for attribute scoring.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O MezhdunarodnayaKniga, 113095 Moscow, USSR) V,1- 1936-
Volume(issueXpage/y ear -,65,1993
Supplemental Data
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 1 80, Sendai 980-91 , Japan)
V.1- 1967- Voume(issue)/page/year 43,561, 1992
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,447
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Citric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 538 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; medication; pesticde (HSDB)
Value
3.1
-1.64
4.30E-14
383,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Clomazone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 539 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Clomazone
66450
81777891
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.84
1,369
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Hydronephrotic kidneys in male offspring, decreased
body weight, decreased pup weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NC HRL/ SW Chronic EEC: 256
Notes
Reference Dose; TRED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,178,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5,880
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Clomazone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 540 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
2,531,160
OPP Estimated Environmental Concentration
HRL Ratios (HRL/ SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
36
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 23 ug/L
Non-cancer: 256
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 2.4 ug/L
Cancer:
Herbicide (HSDB)
Value
60-573
2.5
4.13E-08
1,100
18
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Co bait compounds
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 541 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cobalt compounds
38
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
72
150
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
decreased fertility and preimplantation loss
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Journal; Pedogo and Vernon 1993; Chemical tested forthe supplemental
LOAEL was CoCI2.
Speijers, G., et al; Food Chem Toxicol., 20(3): 311-314. Rat study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
168
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Co bait compounds
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 542 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
86,313
6,910,811
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
30
45
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additives as drying agents; glass additives; catalysis (HSDB)
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
Coumarin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 543 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Coumarin
3492
91645
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
16
1.67
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1956/1982
2006
Critical Effect
Liver -jaundice, other or unclassified, Blood - hemorrhage,
Related to Chronic Data - death;
Liver - hepatitis (hepatocellular necrosis), diffuse, Liver -
iver function tests impaired, Blood - changes in platelet
count
Hepatotoxicity; liver effects.
Prevalence Magnitude ,,, „
5 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
No Observed Effect Level (2006)
Supplemental Data (2006)
Lowest Observed Adverse Effect Level from two studies: JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 118,348,1956.
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0555582.
Supplemental Data; Journal; Food and Chemical Toxicology 44 (2006) 462-475
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
37.3
Y/N
Y/N
W/L
W/L
Teratogen
IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Coumarin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 544 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; former food additive (suspended 1954); in PPCPs (HSDB)
Value
140
1.39
9.90E-08
1,900
38
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cresol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 545 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cresol
11192
108394
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
256
760
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Increased absolute and relative liver weight
Prevalence Magnitude
10 9
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTP Tox-09
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
597
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cresol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 546 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
61,486
1,475,929
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
23
35
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; chemical intermediate; degreaser; veterinary medicaton (HSDB)
Value
22
1.95
1.20E-06
25,900
32
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cryolite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 547 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cryolite
24566
15096523
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
23.1
95
5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - food intake (animal), Liver - other changes,
Kidney, Ureter, Bladder - other changes
Increases in emesis, nucleated cells in males, renal
lesions, and a decrease in urine specific gravity.
Gastrointestinal - changes in structure or function of
salivary glands, Skin and Appendages - hair
Prevalence Magnitude , „
87 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BGTOX BG Chemie Toxicological Evaluations, Five Potential
Health Hazards of Existing Chemicals. (Springer- Verlag New York, POB 2485, Secaucus, NJ 07096).
Supplemental Data; EPA OPP (RED)
BAYER (Bayer. AG, Institute fur Toxikologie, Wuppertal, Germany) Volume(issue)/page/year
#15722,1987
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
222
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cryolite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 548 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,560,365
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
13
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide; industrial electrolyte; medication (HSDB)
Value
Assumed
persistent
250-320
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Cupferron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 549 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cupferron
5877
135206
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude ,,, ,,, „
1 1 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.22
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.159
Y/N
Y/N
W/L
W/L
OEHHA; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cupferron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 550 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Laboratory reagent (HSDB)
Value
15 days
Freely soluble
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Cure-Rite 18
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 551 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cure-Rite 18
23329
13752517
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
35.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Kidney,
Ureter, Bladder -other changes, Nutritional and Gross
Metabolic - weight loss or decreased weight gain
Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS0536514
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
82.7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cure-Rite 18
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 552 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rubber accelerator (West Coast Polychem.com - manufacturer)
Value
38 days
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Cyanazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 553 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanazine
27282
21725462
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
0.985
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
Critical Effect
Reduced body weight and body weight gain, increased
platelet count, decreased protein, albumin and calcium
Behavioral - food intake (animal), Reproductive - Maternal
Effects- breasts, lactation (prior to or during pregnancy),
Tumorigenic - carcinogenic by RTECS criteria
Prevalence Magnitude , „ ,
94 L' L
HRL Ratio(s)
NC HRL/NAWQA 90% : 16.5
CAR HRL/NAWQA 90% : 0.049
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1993; Basis NOEL, dog, UF = 300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 371 -day oral study in rat; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volume(issue)/page/year 60,567,2000
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.84
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ
CADWIMAC
Y
Y
0.07
14
0.042
0.6
0.01
Y/N
Y/N
mg/L
W/L
W/L
W/L
mg/L
Developmental; Teratogen
RAIS
CACART; UMD
Drinking Water Equivalent Level
World Health Organization Drink ng Water Guide
Canadian Drink ng Water Interim Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cyanazine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 554 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,164
# Sam pies
Amount
Released
20,233,056
0
370
n
PWSs/Sites/Sa
mples
317
33
590
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
145
3
0
8.24
% Samples with
detects
Number of
States
48
0
1
%
PWSs/Sites/Sam
pies with
detects
44.9
42.1
0
0.002
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer: 16.5
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
160
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.332
0.355
Not Detected
0.039
Median value of
Detects
0.849
90% of
Detects
6.7
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
95% of
Detects
0.007
0.128
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer: 0.049
Notes
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient
Pesticide Pilot Monitoring Program (USGS/EPA) Finished
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Cancelled herbicide (HSDB)
Value
124
2.22
2.96E-12
170
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Cyanogen chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 555 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cyanogen chloride
7358
506774
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
WHO TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.054
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
Critical Effect
Weight loss, thyroid effects and myelin degenration
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2
350
Y/N
Y/N
mg/L
W/L
W/L
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NCHRL/DBPICR90%: 43.8
Notes
Reference Dose
Reference Dose; basis NOAEL = 25.3 mg/kg-d, UF/MF = 500; chronic oral rat study; Howard and
Han zal, 1955.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cyanogen chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 556 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
# PWSs/Sites
sampled
1,745
#with Detects
1,358
% PWSs/Sites
with detects
78
Mean value of
Detects
3.69
Maximum
value of
Detects
21
Median value of
Detects
2.7
90% of
Detects
8
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# Sam pies
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% Samples w/
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 43.8
Amount Range
Military gas; warn
Value
15
-0.38
2.50E-02
60,000
44
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
Notes
Cancer:
ng agent in fumgants; in chemica sysnthesis (HSDB)
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades Slowly
-------
Cyanuric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 557 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanuric acid
4719
108805
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
150
30
3,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1962
Critical Effect
Functional and histopatological effects in the kidney;
increases in absolute and relative kidney weights and
relative adrenal weights.
Kidney, Ureter, Bladder - other changes, Nutritional
and Gross Metabolic - weight loss or decreased weight
gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
8 3 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; QISAAA Qigiena i Sanitariya.
For English translation, see HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/page/year 27(1 2),1 3,1 962; The LOAEL was used for Potency scoring because
it was lower than the NOEL from other studies.
Supplemental Data
ZKMAAXZhurnal Eksperimental'noi i Klinicheskoi Meditsiny. Journal of Experimental and Clinical
Medicine. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1962-
Volume(issue)/page/year25,345,1985
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
70
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyanuric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 558 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100-500M
>100-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; laboratory reagent (HSDB)
Value
66-124
1.38E-18
2,000
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cyanuric chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 559 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanuric chloride
4716
108770
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1392
Critical Effect
Liver - changes in liver weight, Blood - pigmented or
nucleated red blood cells, Related to Chronic Data -
death
Behavioral - somnolence (general depressed activity),
Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain
Prevalence Magnitude ,,, „
8 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 lexicologist. (Soc. of Toxicology, Inc., 475 Wolf
Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue);page;year 12,119,1992; 28 day study
in rat
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information,
see MTPEEI Vo ume(issue)/page/year 12(81,35,1968
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
233
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cyanuric chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 560 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10M-50M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
60
124
4.90E-07
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
Cyclanilide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 561 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclanilide
69562
113136779
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
21.2
208
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1997
Critical Effect
Liver- liverfunction tests impaired, Liver-other
changes, Liver - changes in liver weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „, „ , „
7 5 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FEREAC Federal Register. (U.S. Government Printing
Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year
62,28350,1997
Supplemental Data
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC
20402) V.1- 1936- Volume(issue)/page/year 62,28350,1997
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
49.5
Y/N
Y/N
W/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyclanilide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 562 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
177,086
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
9
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide; plant growth regulator (HSDB)
Value
95 days
194-565
3.25
7.31 E-10
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reclaitrant (HSDB)
-------
Cyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 563 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexane
4884
110827
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
813
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg*g
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NPIRI Raw Material Data Handbook, Vol.1 Organic Solvents, 1974. (National Assoc. of Printing Ink
Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA
1801 5) Volume(issueXpage/year 1 ,17,1 974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
56.9
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyclohexane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 564 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
10,761
4,761 ,999
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
26
49
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
1997
2004
2004
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Value
15 days
160
3.44
0.15
54
Units
length of time
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Cyclohexanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 565 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexanol
4730
108930
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral -somnolence (general depressed activity),
Lungs, Thorax, or Respiration - other changes,
Nutritional and Gross Metabolic -weight loss or
decreased weight gain
Prevalence Magnitude , „ ,
8 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS053861 7
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
98
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Cyclohexanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 566 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
9,053
4,538,466
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
3
13
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>500M-1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate (HSDB)
Value
13-111
1.23
0.00012
42,000
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Cyclohexanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 567 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexanone
4731
108941
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5
5
0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1994
Critical Effect
Body weight depression
Body weight depression
Behavioral - alteration of classical conditioning
Prevalence Magnitude
10 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Lijinsky and Kovatch, 1986; Basis NOAEL =462 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Lijinsky and Kovatch, 1986; Bass NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,455,1994
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35,000
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyclohexanone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 568 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; degreasing agent; solvent; chem cal intermediate (HSDB)
Value
15.2
0.81
9.00E-06
25,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cyclohexylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 569 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexylamine
4729
108918
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.2
97.8
11
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1958
Critical Effect
Testicular damage. Testicular atrophy, decreased
fertility & live young/litter
Testicle
Liver - other changes, Kidney, Ureter, Bladder - other
changes
Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Gastrointestinal - other
changes
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Gaunt el al., 1976; Basis NOAEL = 18 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Gaunt et al., 1976; Basis NOAEL/LOAEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in rat;VOONAW Voprosy Onkologii. Problems
of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow,
USSR) V. 1-10, 1928-37; V.1- 1955- Volume(issue)/paqe/year 4,659,1958
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0534836
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,400
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyclohexylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 570 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; boiler water additive; rubber accelerant (HSDB)
Value
40.4
1.49
4.16E-06
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Cyfluthrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 571 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyfluthrin
48890
68359375
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.025
0.02
300
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Decreased body weights in males, inflam matory foci in
kidneys of females
Decreased body weights in males, inflammatory foci in
kidneys of females
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
NCHRL/SW Chronic EEC: 1,346
Notes
Reference Dose
Reference Dose; Mobay Chemical, 1983a; Basis NOEL = 2.5 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Mobay Chemical, 1983a; Basis NOEL/LEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; from JECFA evaluation
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
85KYAH "Merck Index; an Encyc opedia of Chem cals, Drugs, and Biologicals", 1 1th ed., Rahway, NJ
07065, Merck&Co., Inc. 1989 Volume(issue)/page/year 11,432,1989
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
175
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyfluthrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 572 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
# Sam pies
Amount
Released
177,782
0
0
n
PWSs/Sites/Sa
mples
134
265
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
29
0
0
%
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.13 ug/L
Non-cancer: 1,346
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Finished and Ambient
Ground water chronic: 0.00336 ug/L
Cancer:
nsecticide; medication (HSDB)
Value
179,000
5.95
1.50E-10
0.003
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Cypermethrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 573 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cypermethrin
35676
52315078
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.06
0.01
0.01
0.05
25
24.6
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
1996
1985
Critical Effect
Clinical signs of neurotoxicity & mortality; decreased
body weight £ body weight gain
G.I tract disturbances
G.I tract
mmunological Includ ng Allergic - decrease in cellular
immune response, Immunological Including Allergic -
decrease in humoral mmune response
Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Gastrointestinal - changes in structure or function of
salivary glands
Prevalence Magnitude , „ ,
10 5 L"L
HRL Ratio(s)
NC HRL/SW Chronic EEC: 32,308
Notes
Reference Dose; ICI Americas, Inc., 1982a
Reference Dose; ICI Americas, Inc., 1982a; Basis NOEL = 1 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; ICI Americas, Inc., 1982a; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake; from JECFA evaluation
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 3-week oral study in rat; ATSUDG Archives of Toxicology,
Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)
No.1- 1978- Volume(issue)/page/year 8,305,1985
Supplemental Data
JEBIDP Journal of Environmental Biology. (Academy of Environmental Biology, India, 657/5, Civil Lines
(South), Muzaffarnagar, 251001, India) V.1- 1980- Volume(issue)/page/year 11,331,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
420
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cypermethrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 574 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
# Sam pies
Amount
Released
187,991
n
PWSs/Sites/Sa
mples
134
380
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
29
/O
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.013 ug/L
Non-cancer: 32,308
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program 2001
Pesticide Data Program 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Finished and Ambient
Ground water chronic: 0.0036 ug/L
Cancer:
nsecticide; veter nary medication (HSDB)
Value
108,000
6.06
4.21 E-07
0.004
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Cyromazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 575 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyromazine
42395
66215278
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0075
0.0075
0.02
3,387
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Effects on hematocrit & hemoglobin levels
Blood
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, ,,, „
7 3 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Ciba-Qeigy, 1980; Basis NOEL = 0.75 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; Ciba-Geigy, 1980; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,217,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
52.5
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Cyromazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 576 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
14,297
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide; medication (HSDB)
Value
60 days
2,104
0.96
5.65E-14
13,000
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Dacthal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 577 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dacthal
12322
1861321
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
0.01
0.01
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Effects on the lungs, liver, kidney (chronic
nephropathy), thyroid. Decreased T4 & T3.
Centrilobular hepatocyte swelling (hepatocytic
hypertrophy)
Lungs; liver; kidney; thyroid; eyes
Lungs; liver; kidney; thyroid;
Prevalence Magnitude ,,, „
9 2 NL'
HRL Ratio(s)
NC HRL/NAWQA 90%: 2,800
Notes
Reference Dose; ISK Biotech Corp., 1993
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL = 1 mg/kg-d, rat, UF = 100
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL/LOAEL, rat, UF = 100
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL/LOAEL, rat, UF = 101
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1988
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.4
70
Y/N
Y/N
mg/L
W/L
W/L
1988
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dacthal
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 578 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Sam pies
Amount
Released
596,723
n
PWSs/Sites/Sa
mples
288
582
286
445
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
16
8
1
6.25
% Samples with
detects
Number of
States
38
%
PWSs/Sites/Sam
pies with
detects
5
3.5
0.35
0.000004
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.21
Non-cancer: 2,800
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
100
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.014
0.004
0.21
0.003
Median value of
Detects
0.025
90% of
Detects
1
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.21
95% of
Detects
0.002
0.21
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient 2001 (GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) Finished 2001 (GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
60 days
283
4.28
2.18E-06
0.5
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Dacthal mono di-acid degradate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 579 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dacthal mono/di-acid degradate
79261
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
Scores based on parent
HEALTH EFFECTS DATA1 See Dacthal parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Effects on the lungs, liver, kidney (chronic
nephropathy), thyroid. Decreased T4 & T3.
Centrilobular hepatocyte swelling (hepatocytic
hypertrophy)
Prevalence Magnitude , „
97 L
HRL Ratio(s)
NCHRL/UCMR90%: 11.1 (HRL for parent Dacthal)
Notes
Reference Dose (for parent, dacthal); ISK Biotech Corp., 1993
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
70
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on data for parent Dacthal
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dacthal mono di-acid degradate
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 580 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,612
171
4.73
1
190
2
6.3
18
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
2,217
445
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
39
6.25
% Samples with
detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
1.76
0.000004
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
1
Non-cancer: 11.1
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
100
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
13
0.003
Median value of
Detects
0.025
90% of
Detects
1
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
Analytical method reports mono- and di- as total.
(data for parent, dacthal)
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1.9
90% of
Detects
5.3
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
HRL for parent Dacthal
Degradates of the herbicide dimethyl tetrachloroterephthalate (HSDB)
Value
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Decabromodiphenyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 581 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Decabromodiphenyl ether
10800
1163195
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL-Int
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.007
0.01
10
1
800
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2008
2004
1975, 1994
Critical Effect
Neurobehavioral effects
Liver - other changes, Kidney, Ureter, Bladder - other
changes, Endocrine - changes in thyrod weight (goiter)
Prevalence Magnitude , „ ,
10 8 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis NOEL = 2.2 mg/kg, UF = 300, single-dose gavage in mice. Viberg, et al,
2003.
Reference Dose
Reference Dose; Kociba et al., 1975; Basis NOAEL, rat, UF=100
Minimal Risk Level-lnt
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,316,1994.
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
5
0.0007
Suggestive
evidence
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
2008
2008
2008
IRIS
IRIS
IRIS
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
50
Y/N
Y/N
W/L
W/L
EPA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Decabromodiphenyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 582 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,827
953,472
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
9
26
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame retardant; polymer intermediate (HSDB)
Value
409,000
12.1
4.45E-08
0.025
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Decamethylcyclopentasiloxane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 583 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Decamethylcyclopentasiloxane
7678
541026
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
24,134
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
8 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information, Volume issue)/page/year OTS0572801
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,689
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Decamethylcyclopentasiloxane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 584 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n PPCPs; chemical intermediate; in petroleum processing (HSDB)
Value
38 days
16,000
5.2
0.306
0.017
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Desethylatrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 585 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Desethylatrazine
17458
6190654
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Attenuation of preovultory luteinizing hormone (LH)
surge, as a biomarker indicative of hypothalmic
function disruption
Prevalence Magnitude
10 3
HRL Ratio(s)
NC HRL/NAWQA 90% : 881 (HRL for parent Atrazine)
Notes
Reference Dose; evaluation is based on the RfD for parent (Atrazine).
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
126
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on data for parent Atrazine
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Desethylatrazine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 586 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,151
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
317
154
2,963
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
154
75
203
167
41.4
% Samples with
detects
Number of
States
/o
PWSs/Sites/Sam
pies with
detects
48.6
48.7
89
74.6
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0413
0.0413
Non-cancer: 881
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
10
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.19
0.22
0.352
0.267
0.017
Median value of
Detects
0.143
90% of
Detects
0.738
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
95th % lie
value of
Detects
0.265
0.201
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
2002
2001
HRL for parent Atrazine
Degradation product of atrazine (HSDB)
Value
24-30,000
1.51
1.50E-09
3,200
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
Desisopropylatrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 587 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Desisopropylatrazine
10412
1007289
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Attenuation of preovultory luteinizing hormone (LH)
surge, as a biomarker indicative of hypothalmic
function disruption
Prevalence Magnitude , „
10 4 L'
HRL Ratio(s)
NC HRL/NAWQA 90% : 200 (HRL for parent Atrazine)
Notes
Reference Dose; evaluation is based on the RfD for parent (Atrazine)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
126
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on data for parent Atrazine
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Desisopropylatrazine
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 588 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
418
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
317
154
94
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
127
64
250
146
22.5
% Samples with
detects
Number of
States
/o
PWSs/Sites/Sam
pies with
detects
40.1
41.6
80.1
64.9
0.003
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0163
0.0163
Non-cancer: 200
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
3.69
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.0832
0.073
0.386
0.178
0.1
Median value of
Detects
0.63
90% of
Detects
2.04
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% value of
Detects
0.195
0.081
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
2002
2001
HRL for parent Atrazine
Degradation product of atrazine
Value
60 days
1.15
1.16E-09
670
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
D-Glucose
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 589 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
D-Glucose
2156
50997
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
714
100
25,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Increased heart rate; early dumping syndrome
Behavioral - coma, Lungs, Thorax, or Respiration -
cyanosis, Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude ,,, ,,, „
95
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Journal -Andrew Ukleja. Feb 2006. "Dumping Syndrome." Practical
Gastroenterology. Series 35: Nutrition Issues in Gastroenterology. pp 32-46. (Series Editor: Carol
Rees Parrish, RD, MS)
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
85AIAL "Toxicity of Pure Foods," Boyd, E.M., Cleveland, OH, CRC Press, 1973 Volume(issue)/page/year -
,39,1973
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,666
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
D-Glucose
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 590 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; in medical nutrient solutions; chemica ntermediate (HSDB)
Value
8.7 days
-3.24
1,200,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (PBT)
-------
Diallyl glycol carbonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 591 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diallyl glycol carbonate
6128
142223
Attribute Scores
Potency Severity
4 6
Prevalence Magnitude
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
42.6
279
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Brain and Coverings - recordings from specific areas
of CNS, Liver - liver function tests impaired, Kidney,
Ureter, Bladder - renal function tests depressed
Brain and Coverings - recordings from specific areas of
CNS, Behavioral - somnolence (general depressed
activity), Lungs, Thorax, or Respiration - other changes
3-model Categorical Prediction
NL7-L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii
per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year(2),35,1999
Supplemental Data
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown
Volume(issue)/page/year (2), 35, 1999
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
99.4
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diallyl glycol carbonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 592 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
38 days
40
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Diallyldimethylammonium chlorid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 593 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diallyldimethylammonium chloride
18770
7398698
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,000
7,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1984
Critical Effect
Liver -other changes, Kidney, Ureter, Bladder -
changes in tubules (including acute renal failure, acute
tubular necrosis), Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect level, GTPZAB Qigiena Truda i Professional'nye Zabolevaniya.
Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 1 13095 Moscow, USSR)
V.1 -36, 1957-1992. For publisher information, see MTPEEI Volume(issueXpage/year 28(7),53,1 984;
6 week mammal study
Supplemental Data
rodent-mouse; GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For
publisher information, see MTPEEI Volume(issue)/page/year 28(7), 53, 1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,333
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diallyldimethylammonium chlorid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 594 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Polymer intermec
Value
1 5 days
-2.49
1,000,000
39
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Diazinon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 595 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diazinon
6596
333415
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002
0.00009
0.0009
0.0002
0.002
0.143
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Plasma CUE inhibition
Decreased cholinesterase activity
Liver - fatty liver degeneration, Nutritional and Gross
Metabolic - weight loss or decreased we ght gain
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 3.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1984; Basis NOAEL, UF = 100
Minimal Risk Leve ; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year 37,501,1986
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
Y
0.003
1.4
0.02
Y/N
Y/N
mg/L
M/L
M/L
mg/L
Teratogen
UMD
Drinking Water Equivalent Level
Canadian Drinking Water Maximum Acceptable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Diazinon
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 596 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,115
85
# Samples
Amount
Released
918,087
10,287
23,769
n
PWSs/Sites/Sa
mples
283
658
6,743
815
22
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
1
114
6
11.45
25.9
% Sam pies with
detects
4.89
0.49
Number of
States
37
2
7
%
PWSs/Sites/Sam
pies with
detects
0.4
0.2
35.3
0.09
0.0009
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.01
0.01
0.01
Non-cancer: 13.2
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
19
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
0.01
0.01
0.101
507
0.014
0.07
Median value of
Detects
0.125
0.18
0.106
90% of Detects
0.63
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.12
90% of Detects
203
95% of Detects
0.002
Cancer:
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA)
Ambient
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Che
micalcontaminants.aspx
Pesticide; veterinary medication (HSDB)
Value
38 days
1,337
3.81
1.13E-07
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Diazinon oxygen analog
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 597 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diazinon oxygen analog
79205
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
Scores based on parent
HEALTH EFFECTS DATA1 See Diazinon Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Plasma ChE inhibition
Prevalence Magnitude ,,,
1 1 NL
Scores based on parent HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose (for parent)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.4
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on data for Parent Diazinon
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diazinon oxygen analog
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 598 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data- FOR
DIAZINON PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
283
664
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
3
% Samples with
detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.4
0.5
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.04
0.015
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.04
0.037
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
(Data for parent)
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Analog of the pestcide diazinon
Value
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Dibromoacetonitrile (DBAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 599 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dibromoacetonitrile (DBAN)
14629
3252435
Attribute Scores
Potency
5
Severity
Prevalence
10
Magnitude
7
3-model Categorical Prediction
Incomplete data for scoring
HEALTH EFFECTS DATA1
NCHRL/DBPICR90%: 14.7
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
NTP Carcinogen Studies
3
Some evidence -
Clear evidence
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1999
2008
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
45.5
Y/N
Y/N
mg/L
M/L
M/L
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
National Toxicology Program TR-544
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Dibromoacetonitrile (DBAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 600 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBPICR
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
48.6
Mean value of
Detects
1.61
Maximum
value of
Detects
24
Median value of
Detects
1.2
90% of
Detects
3.1
99% of Detects
Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount Released
# Sam pies
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% Sam pies w/
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 14.7
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
Notes
Cancer:
Disinfection By-Product
Value
38
13
0.47
4.06E-07
9,600
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze
-------
Dibromomethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 601 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibromomethane
2611
74953
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
11.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
increased carboxyhemoglobin
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - dehydrogenases; plasma
urea and mild histological changes
Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 10.9
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1987; Basis NOAEL, UF= 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 41,515,1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
70
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dibromomethane
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 602 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
16,549
23,006
60
108
0.363
0.469
0.1
0.00055
21.1
16.2
1.4
1.1
6.4
5.3
21.1
16
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasner, et al.
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,308
# Sam pies
Amount
Released
0
24,935
n
PWSs/Sites/Sa
mples
11,883
12
5
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
16
1
0.116
% Samples with
detects
Number of
States
0
4
%
PWSs/Sites/Sam
pies with
detects
0.13
8.33
0.01
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.55
Non-cancer: 10.9
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.2
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
14
0.1
Median value of
Detects
0.1
90% of
Detects
0.2
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.895
ND
90% of
Detects
2.45
Units for Mag
data
ug/L
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Techno!. , 40, pp 71 75-71 85 (and related documentation).
Organic synthesis; solvent (HSDB)
Value
15 days
23.7
1.7
0.000822
11,900
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slowly
-------
Dibutyltin dichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 603 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibutyltin dichloride
9364
683181
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL-Int
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
2.5
5
0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2003
1977
Critical Effect
depressed humoral response against SRBC
mmunological Includ ng Allergic - decrease in humoral
immune response
Complete resorption of implanted embryos, increased
incidence of post implantation loss, cleft jaw, decreased
weight gain.
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 4-week oral study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year42,213,1977
Supplemental Data; Toxicol letters 58:347-356, 1991
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1248,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dibutyltin dichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 604 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; polymer intermediate; chemical intermediate (HSDB)
Value
1.56
92
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Dibutyltin oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 605 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibutyltin oxide
9781
818086
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0,171
44.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1977
Critical Effect
Behavioral -alteration of classical conditioning, Blood •
normocytic anemia, Blood -changes in erythrocyte
(RBC) count
Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (VYOMezhdunarodnayaKniga, 113095 Moscow, USSR) V,1- 1936-
Volume(issueXpage/year 42(4), 14, 1977, 26-week, rodent-rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.4
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dibutyltin oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 606 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial Chemical (EPA/SRS)
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Dichloran
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 607 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dichloran
4022
99309
Attribute Scores
Potency Severity
5 7
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
74.8
1,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1968
Critical Effect
ncreased alkaline phosphatase & cholesterol,
increased liver weights, hepatocyte hypertrophy,
vacuolar alterations of the brain and spinal cord,
prostate atrophy, degeneration of the seminiferous
tubules, & hypospermia in the epididymides
Liver - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels -
transaminases, Related to Chronic Data - death
Details of toxic effects not reported other than lethal dose
value
3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/SW Chronic EEC: 97.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Pharmacology. (Academic Press, Inc.
Volume(issue)/page/year 1 2,31 4,1 968
; 2 year dog study; TXAPA9 Toxicology and Applied
1 E. First St., Duluth, MN 55802) V.1- 1959-
Supplemental Data
rodent-guinea pig; PCOC Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year -,343,1966
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
175
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dichloran
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 608 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
CAL DHS
# Sam pies
Amount
Released
188,683
0
0
n
PWSs/Sites/Sa
mples
11
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
2
0
0
%
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 1 .8 ug/L
Non-cancer: 97.2
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 1 .3 ug/L
Cancer:
Fungicide; in dyes (HSDB)
Value
6.3
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Dichloroacetaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 609 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroacetaldehyde
2854
79027
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
M
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
mg/L
W/L
W/L
Prevalence Magnitude
10 6
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; M = Medium probability of being carcinogenic
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dichloroacetaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 61 Oof 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al. and related documentation
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
12
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12
Number of
States
%
PWSs/Sites/Sam
pies with
detects
100
Units
States
States
States
Minimum value of
Detects
ND
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
14
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
90% of
Detects
Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 71 75-7185 (and related documentation).
Cancer:
Disinfection By-Product
Value
38
4.3
0.27
8.40E-06
140,000
52
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation
-------
Dichloroacetonitrile (DCAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 611 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroacetonitrile (DCAN)
14263
3018120
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
W/L
W/L
Teratogen
Prevalence Magnitude
10 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dichloroacetonitrile (DCAN)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 612 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF ICR
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
70.1
Mean value of
Detects
2.59
Maximum
value of
Detects
24.6
Median value of
Detects
1.97
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al. and related documentation
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
12
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12
Number of
States
/o
PWSs/Sites/Sam
pies with
detects
100
Units
States
States
States
Minimum value of
Detects
ND
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
12
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
1
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 7175-7185 (and related documentation).
Disinfection By-Product
Value
38
13
0.29
3.79E-06
33,500
51
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze
-------
Dichloroiodomethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 613 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroiodomethane
8286
594047
Attribute Scores
Potency Severity
Prevalence Magnitude
10 5
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification
M
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
mg/L
W/L
W/L
3-model Categorical Prediction
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DSSTOX; M = Medium probability of being carcinogenic
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dichloroiodomethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 614 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., (and related
documentation)
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
n
PWSs/Sites/Sa
mples
12
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12
Number of
States
/o
PWSs/Sites/Sam
pies with
detects
100
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
11
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.3
90% of
Detects
Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 7175-7185 (and related documentation).
Cancer:
Disinfection By-Product
Value
38
2.03
33
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation
-------
Dichlorvos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 615 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dichlorvos
2444
62737
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
0.0005
0.0005
0.004
0.625
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
1990
1997
1993
Critical Effect
Cholinesterase inhibit on
Plasma and RBC ChE inhibition; blood
Neurol.
Brain and Coverings - other degeneratve changes,
Kidney, Ureter, Bladder - urine volume increased,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - true Cholinesterase
Prevalence Magnitude ,,
1 1
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, AMVAC Chemical Corporation, 1990, NOAEL, dog, UF=100; Basis NOAEL = 0.05
mq/kq-d
Reference Dose
Reference Dose, AMVAC Chemical Corporation, 1990, NOAEL/LOAEL, dog, UF=100
Minimal Risk Level; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day dog study; NYZZA3 Nippon Yakuzaishikai Zasshi.
Journal of the Japan Pharmaceutical Association. (Nippon Yakuznishikai, 2-1 2-1 5 Shibuya, Shibuya-ku,
Tokyo 150, Japan) V.1- 1949- Volume(issue)/page/year 26,739,1974
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 1014
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.01
0.29
0.41
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1989
1991
Gl, pancreas, leukemia
IRIS
NTP, 1986
Vol. 53
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
Y/N
Y/N
W/L
W/L
Teratogen list
EPA, RAISHE, OEHHA, IARC, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dichlorvos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATAT
EPA-OGWDW
August 2009
Page 616 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP
PPMP
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
264
n
PWSs/Sites/Sa
mples
n
PWSs/Sites/Sa
mples
107
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
#with Detects
% Samples with
detects
0
0
Number of
States
0
3
/O
PWSs/Sites/Sam
pies with
detects
0
0
%
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Not Detected
Not Detected
Units
States
States
States
Minimum value of
Detects
0
0
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Not Detected
Not Detected
Year
1997
2004
2004
Maximum
value of
Detects
0
0
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
Not Detected
90% of
Detects
Not Detected
Not Detected
99% of Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0
0
Median value of
Detects
Not Detected
99% of
Detects
0
0
90% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
Pesticide Pilot Mentoring Program (USGS/EPA) 9002(GC/MS); Ambient
Pesticide Pilot Mentoring Program (USGS/EPA)9002(GC/MS); Finished
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Insecticide; veter nary medicine (HSDB)
Value
<1 -3. 5 days
40.2
1.47
5.75E-07
8,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Dicofol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 617 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dicofol
5106
115322
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0012
0.002
22.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Adrenal effect: Inhibition of adrenal cortical trophic
hormone (ACTH), stimulated release of cortisol
Related to Chronic Data - death
Prevalence Magnitude
10 6
HRL Ratio(s)
NCHRL/SW Chronic EEC: 16.8
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; one year dog study; HBPTO Handbook of pesticide toxicology.
Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1342,2001
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
8.4
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dicofol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 618 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
# Sam pies
Amount
Released
786,805
0
33
n
PWSs/Sites/Sa
mples
21
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
36
0
2
/O
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.5 ug/L
Non-cancer: 16.8
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.069 ug/L
Cancer:
nsecticide; (HSDB)
Value
10,500
5.02
2.42E-07
0.8
3
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Dicyclopentadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 619 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dicyclopentadiene
2762
77736
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
100
1
190
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1986
Critical Effect
None observed
reproductive/developmental
Behavioral - alteration of classical conditioning,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - multiple enzyme effects
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
9 8 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, NOEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year51(2),77,1986
Supplemental Data
mouse study; 40QBA3 "Proceedings of the International Congress on Toxicology, Toxicology as a
Predictive Science, 1st, Toronto, 1977," Plaa, G.L., and W.A. Duncan, eds., New York, Academic Press,
nc., 1978 Volume(issue)/paqe/year-, 448, 1978
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dicyclopentadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 620 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
5,234
392,668
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
22
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in flame retardants; animal repellant (HSDB)
Value
15 days
1,800
3.16
6.26E-02
51.9
75
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Dieldrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 621 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dieldrin
2415
60571
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
0.00005
0.00005
0.00005
0.0001
0.0001
0.0083
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
2000
1994
2000
1973
Critical Effect
rritability, tremors, occasional convulsions. Increased
absolute & relative liver weights. Liver parenchyma cell
changes including focal proliferation & focal hyperplasia
iver
iver
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Immunological Including Allergic - decrease
in humoral immune response, Biochemical - Metabolism
(Intermediary) - other proteins
iver
Prevalence Magnitude , „ ,
36 L' L
HRL Ratio(s)
NC HRL/NCOD R2 90% : 0.8
CAR HRL/NCOD R2 90% : 4.5
Notes
Reference Dose
Reference Dose; Walker et al., 1969, Basis NOAEL = 0.005 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, Walker et al., 1969, Basis NOAEL/LOAEL, rat, UF=100
Minimal Risk Level, Walker et al., 1969, Basis NOAEL = 0.005 mg/kg-d, rat, UF=100
Acceptable Daily Intake; combined total Aldrin + Dieldrin; see also Aldrin
Acceptable Daily Intake
Tolerable Daily Intake; Fitzhugh et al., 1964; Treon & Cleaveland, 1955, Basis LOAEL = 0.025 mg/kg-d;
UF = 250; rat and dog study
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rabbit study; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 10,42,1973
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
16
16
B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
1987
IRIS
Vol. 5, Suppl 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.002
0.35
0.002
Y/N
Y/N
W/L
W/L
teratogen list
CACART; EPA; RAISHE; OEHHA
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dieldrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 622 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
1 1 ,843
21
0.177
0.02
4.4
0.5
4.4
4.4
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,100
85
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
# Sites
5,212
205
4
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
0
#with Detects
4
2.89
4.70
% Samples with
detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0.3
0
% Sites with
detects
0.08
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
0.01
Non-cancer: 0.8
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
5.60
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Maximum
value of
Detects
7
0.0097
0.180
Median value of
Detects
0.034
90% of
Detects
2.48
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Median value of
Detects
0.0225
99% of
Detects
90% of
Detects
4.91
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer: 4.5
Notes
Pesticide Pilot Mentoring Program (USGS/EPA) Ambient
Pesticide Pilot Mentoring Program (USGS/EPA) Finished
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Restricted insecticide (HSDB)
Value
10,600
5.2
1.00E-05
0.25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DST
Notes
DST = Degrades sometimes/recalcitrant (HSDB)
-------
Diethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 623 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethanolamine
4937
111422
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
10 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
changes in liver and kidney weights
3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP information from HSDB, NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
2000
Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 624 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
55,403
1,396,761
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
14
29
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate; in cutting oi s and PPCPs; in
Value
4
-1.43
1,000,000
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF/BFA/BSA
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ubricant production (HSDB)
Notes
BF = Biodegrades fast/BFA = Biodegrades fast with acclimation/BSA = Biodegrades slow with acclimation (BIODEG)
-------
Diethyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 625 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethyl sulfate
2468
64675
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
647
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 5 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear PB214-270
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1999
Vol. 54, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
Y/N
Y/N
M8/L
W/L
Teratogen list
IARC, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 626 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
10,644
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1.7 hours
1.14
7,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Chemical intermediate (HSDB)
DF = Degrades fast (HSDB)
-------
Diethylbenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 627 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylbenzene
28613
25340174
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.643
3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date
1975
1975
Critical Effect
Vascular- regional or general arteriolar or venous
dilation, Liver - other changes, Blood - changes in
serum composition e.g. TP, bilirubin, cholesterol)
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(6), 90,1 975; 6-wk rabbit study
Supplemental Data
rabbit study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 40(6), 90,1975
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.50
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethylbenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 628 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
1 5 days
4.07
0.021
31.9
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Diethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 629 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylene glyco
4941
111466
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
1,250
375
2,300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1937
Critical Effect
Maternal toxicity; increases in absolute and relative
kidney weights
Related to Chronic Data - death
Brain and Coverings - other degeneratve changes, Liver -
other changes, Kidney, Ureter, Bladder - other changes
Prevalence Magnitude , „
9 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information available; scored on CTDJPN NOEL.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP study TER89001
Lowest Observed Adverse Effect Level; 7 week rat study; JAMAAP JAMA, Journal of the American
Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883-
Volume(issue)/page/vear 1 09, 1 51 7, 1 937
Supplemental Data
Mouse study; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,145,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
8,750
Y/N
Y/N
W/L
W/L
teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Diethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 630 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; humectant; antifreeze; in PPCPs (HSDB)
Value
1
1.47
2.00E-09
1,000,000
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Diethylene glycol monobutyl eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 631 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylene glyco monobutyl ether
5022
112345
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
hematological effects
Prevalence Magnitude „,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Hobson et al.r 1987, NOAELJADJ, rat, UF=3,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
70
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethylene glycol monobutyl eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 632 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; chemical intermediate; industrial so vent (HSDB)
Value
10
0.56
4.45E-11
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Diethylenetriamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 633 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylenetriamine
4935
111400
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
1,080
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1372
Critical Effect
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels -transaminases
Behavioral - convulsions or effect on seizure threshold
Prevalence Magnitude
8 5 NU
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 37(7),103,1 972, LOAEL, 26 week rabbit study
Supplemental Data
AMIHABAMA Archives of Industrial Health. (Ch cago, IL) V.11-21, 1955-60. For publisher information,
see AEHLAU. Volume(issue)/page/year 17,129,1958
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
23
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethylenetriamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 634 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
u
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; industrial solvent; chelating agent (HSDB)
Value
-2.13
3.15E-07
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Diethyltoluenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 635 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethyltoluenediamine
51017
68479981
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
472
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral - somno ence (general depressed activity),
Musculoskeletal - other changes
3-model Categorical Prediction
NL?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issuej/page/year OTS0537598, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diethyltoluenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 636 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial Chemical (EPA/SRS)
Value
38 days
20
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Difenzoquat methyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 637 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Difenzoquat methyl sulfate
34821
43222486
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.08
0.08
25
40
40
206
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1983
Critical Effect
Decreased body weight gain
Decreased body weight
Decreased weight
Blood - pigmented or nucleated red blood cells, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol), Liver - other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, „
8 6 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, American Cyanamide Co., 1975, Basis NOEL=25 mg/kg-d, rat, UF=300
Reference Dose
Reference Dose, American Cyanamide Co., 1975, Basis NOEL, LEL, rat, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; KHZDAN Khigiena i Zdraveopazvane.
Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V. 9- 1966- Volume(issue)/page/year
29(6), 42,1983
Supplemental Data
rat study; KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia,
Bulgaria) V.9- 1966- Volume(issue)/page/year 29(6), 42,1983
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,400
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Difenzoquat methyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 638 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
346,308
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
11
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (ChemlDPIus)
Value
118,000
-0.02
5,553
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Diglycidyl resorcinol ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 639 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diglycidyl resorcinol ether
4212
101906
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
143
12
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Related to Chronic Data - death
Decreased survival in males. (Cancer results positive in
both sexes mice and rats).
Prevalence Magnitude
1 1 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rat study; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-257,1986
Supplemental Data; NTP Rep # 257
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
1.7
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
(mg/kg-d)"1
1999
Vol. 36, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
334
0.021
Y/N
Y/N
W/L
W/L
OEHHA; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Diglycidyl resorcinol ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 640 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
1
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n resins; rubber additive (HSDB)
Value
38 days
1.23
38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Dimethyl hydrogen phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 641 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl hydrogen phosphite
9953
868859
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
noneoplastic lesions of the lungs (rats) - Testicular
atrophy in male mice at a dose of 100 mg/kg Clear
evidence of cancer in male rats, equivocal evidence in
female rats and no evidence in mice
Prevalence Magnitude „,, „
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27T09) No.206- Volume(issue)/page/year NTP-TR-287,1985
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol. 48, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
117
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethyl hydrogen phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 642 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10K-500K
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n lubricants; flame retardant; chemcal intermediate (HSDB)
Value
1 9 days
>1 00,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DS
Notes
DS = Degrades slow (HSDB)
-------
Dimethyl laurylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 643 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl laurylamine
5006
112185
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
740
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1322
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethyl laurylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 644 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units
Cancer:
Notes
Chemical intermed ate; corrosion nhibitor (HSDB)
Value
15
21,700
5.4
0.0049
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Dimethyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 645 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl sulfate
2767
77781
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
140
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1979
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 5 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GTPZAB Qigiena Truda i Professional' nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 23(3),28,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
B2
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
1988
1999
Vol. 4, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
Y/N
Y/N
M8/L
W/L
Teratogen list
EPA, IARC, CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethyl sulfate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 646 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
10,221
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
11
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; former war gas (HSDB)
Value
1.2 hours
24.2
0.16
4.01 E-06
28,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Dimethyl terephthalate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 647 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl terephthalate
5339
120616
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
588
125
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
1973
Critical Effect
Chronic kidney inflammation
kidney; chronic inflammation
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude , 0
10 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NCI, 1979, Basis LOAEL = 125 mg/kg-d, rat, UF=1,000
Reference Dose
Reference Dose, NCI, 1979 , LOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 14 week rat study; AIHAAP American Industrial Hygiene
Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
Volume(issue)/page/year34,455,1973
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dimethyl terephthalate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 648 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value
1 5 days
36.3
2.25
0.000134
19
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Dimethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 649 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethylamine
5570
124403
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0,347
240
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
Behavioral - alteration of classical conditioning, Liver -
changesin liver weight, Immunological Including
Allergic -decrease in cellular immune response
Behavioral - excitement, Behavioral - muscle weakness,
Gastrointestinal - ulceration or bleeding from stomach
Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, QISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/0 Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(6), 12,1967, 35 week rat study
Supplemental Data
rabbit and guinea pig studies; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year 32(6), 329,1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.81
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 650 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
25,286
618,880
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
7
26
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rubber additive; chemical intermed ate; fuel additive; photographic chemical (HSDB)
Value
435
-0.38
49
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Dimethyldichlorosilane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 651 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyldichlorosilane
2681
75785
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
9 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G. D. and F. E. Clayton (eds.). Pattys Industrial Hygiene and Toxicology: Volume 2A, 2B,
2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2398
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethyldichlorosilane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 652 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; laboratory chemical (HSDB)
Value
1 5 days
2.24
0.019
1,120
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Dimethyltin dichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 653 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyltin dichloride
9560
753731
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Supplemental LD50
Value
73.9
14
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date
1973
1986
Critical Effect
Details of toxic effects not reported other than lethal dose
value
Neurological damamge to the brain
Prevalence Magnitude
6
Incomplete data for scoring HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
rodent-rat; TRIPA7 Tin Research Institute, Publication. (Middlesex, UK) 1934-76. For publisher
nformation, see IRIPDP. Volume(issue)/page/year -,1,1973
Aldridgeetal, 1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dimethyltin dichloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 654 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n plastics, food packaging, plastics, pesticides and pa nts (organotins)
Value
-1.06
20,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Dinitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 655 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dinitrotoluene
28581
25321146
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.025
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1977
Critical Effect
Weakness, ataxia, tremors, and neurotoxicity
Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
esterases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other oxidoreductases
Prevalence Magnitude „,, „ , „
2 4 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 42(1 0) , 1 7, 1 977
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.005
0.68
B2
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
19990
Liver, mammary gland
EPAHA
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
14
0.05
Y/N
Y/N
W/L
W/L
teratogen list
EPA, RAISHE
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dinitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 656 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
13
6,802
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; plasticizer (HSDB)
Value
38 days
372
2.18
3.96E-07
270
21
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Diphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 657 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diphenylamine
5436
122394
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.025
0.025
0.08
2.5
0.833
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Alterations in clinical chemistry parameters. Increased
absolute & relative kidney, liver & spleen weights
Decreased body weight gain, increased liver and kidney
weights
Gastrointestinal - alteration in gastric secretion, Kidney,
Ureter, Bladder - changes in tubules (including acute renal
failure, acute tubular necrosis), Kidney, Ureter, Bladder -
proteinuria
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
88 '
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Thomas et al., 1967, Basis NOEL=2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose, Thomas et al., 1967, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30 day rat study
Supplemental Data
guinea pig study; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C1 12,1 991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
210
Y/N
Y/N
W/L
W/L
teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Diphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 658 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
97
414,131
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
3
15
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide/herbicide; polymer stab lizer; rubber additve; topical veterinary agent (HSDB)
Value
1,887
3.5
3.40E-06
53
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Dipropylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 659 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dipropylamine
6158
142847
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1970
Critical Effect
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - catalases
Behavioral - changes in motor activity (specific assay),
Behavioral - muscle weakness
Prevalence Magnitude Kll 0
6 7 NL"
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(4),103,1970, 26 week rat and rabbit study
Supplemental Data
rat study; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0544865
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
11.7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dipropylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 660 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
190
1.67
35,100
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Dipropylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 661 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dipropylene glycol
28536
25265718
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6,200
14.8
14,850
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mL/kg
mg/kg
mg/kg
Date
Critical Effect
Kidney lesions
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 7 NU
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, SIDS Summary
Lowest Observed Adverse Effect Level
Supplemental Data
Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley
and Sons, 1978-1984., p. 11 (1980) 936
rodent-rat; 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press,
nc., 1969 Volume(issue)/page/year -, 731, 1969
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
43,400
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dipropylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 662 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; antifreeze; in PPCPs; medication (HSDB)
Value
1
0.64
5.60E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Diquat
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 663 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diquat
13896
2764729
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
0.002
30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Lens opacities cataracts decreased organ weights
epidymusadenals
Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain
Prevalence Magnitude
10 5
HRL Ratio(s)
NC HRL/CAL DHS 90% : 0.3
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; as diquat ion
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME
04046) V.1- 1944- Volume(issue)/page/year 27,51,1970
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
WHOWQ
Y
35
0.07
10
Y/N
Y/N
W/L
W/L
mg/L
Mg/L
teratogen list
UMD
Drinking Water Equivalent Level
Provisional Guideline value
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Diquat
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 664 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
# Sam pies
Amount
Released
266,858
n
PWSs/Sites/Sa
mples
4,867
OPP Estimated Environmental Concentration
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
9
% Samples with
detects
Number of
States
28
%
PWSs/Sites/Sam
pies with
detects
0.18
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.08
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
549
Surface water chronic: 0.4 ug/L
Non-cancer: 0.3
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
4.9
90% of
Detects
115
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.006 ug/L
Cancer:
Herbicide (for diquat dibromide, CASRN 85-00-7)
Value
15
2,000
-4.6
1.40E-13
708,000
20
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
For diquat dibromide
For diquat dibromide
For diquat dibromide
For diquat dibromide
-------
Disodium iminodiacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 665 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Disodium iminodiacetate
10140
928723
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
8,070
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1972
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , 0 ,
97 L" L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut
Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
Volume(issue)/page/year -,128,1972, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Disodium iminodiacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 666 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial Chemical (EPA/SRS)
Value
1 5 days
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Dodecylbenzenesulfonic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 667 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dodecylbenzenesulfonic acid
29930
27176870
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
650
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
85 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger PI. 3, D-1000 Berlin 33, Fed. Rep.
Ger.) V.32- 1974- VoIume(issueXpage/year 32,245,1974, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Dodecylbenzenesulfonic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 668 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Laboratory chem cal; fungicide stabilizer; in electron cs cleaners (HSDB)
Value
1 5 days
4.78
6.27E-08
0.703
ir
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Dodine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 669 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dodine
13332
2439103
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.004
0.004
0.1
1.25
48
176
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2000
1961
Critical Effect
Body weight loss
Thyroid
Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
10 5 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose, American Cyanamid, 1958
Reference Dose, American Cyanamid, 1958, Bass NOEL = 1.25 mg/kg-d, dog, UF=300
Reference Dose
Reference Dose; American Cyanamid, 1958, UF=300, dog
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2 year rat study; TXAPA9 Toxicology and Applied Pharmacology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year
3,127,1961
Supplemental Data
rodent-guinea pig; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year-, 64,1 982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Dodine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 670 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
151,538
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
28
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fungicide (HSDB)
Value
15 days
15,500
1.32
6.02E-19
630
31
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Endosulfan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 671 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Endosulfan
5104
115297
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.006
0.006
0.006
0.002
0.006
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
2000
Critical Effect
Reduced body weight gain, enlarged kidneys,
increased incidences of marked progressive
glomerulonephrosis, & blood vessel aneurysms
red. body weight gain, glomerular nephrosis
red body weight, increased marked progressive
glomrulonephrosis
hepatic; liver
Prevalence Magnitude , „
10 7 L'
HRL Ratio(s)
NC HRL/SW Chronic EEC: 28
Notes
Reference Dose
Reference Dose; Basis NOAEL = 0.7 female and 0.6 male mg/kg-d, Hoechst, 1989a; UF=100
Reference Dose
Reference Dose, Hoechst Celanese Corp. 1989, NOAEL/LOAEL, rat, UF=100
Minimal Risk Level, Hoechst, 1989c, Basis NOAEL = 0.18 mg/kg-d, dog, UF=100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
42
Y/N
Y/N
W/L
W/L
teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Endosulfan
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA
EPA-OGWDW
August 2009
Page 672 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
1,601,195
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
44
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 1 .5 ug/L
Non-cancer: 28
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Ground water chronic: 0.01 2 ug/L
Cancer:
nsecticide (HSDB)
Value
22,000
3.83
6.51 E-05
0.45
5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
EPIC
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 673 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
EPTC
9581
759944
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.025
2.5
112
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1971
Critical Effect
Degenerative cardiomyopathy
Degenerative cardiomyopathy
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, PPG Industries, 1986a, Basis NOEL = 2.5 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, PPG Industries, 1986, NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
mammal- cat; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA)
1964-71. Discontinued. Volume(ssue)/page/year 36(1-3), 196, 1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
175
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
EPIC
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 674 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Sam pies
Amount
Released
8,791,984
12
1,204
n
PWSs/Sites/Sa
mples
115
12
2,243
406
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
5.7
% Samples with
detects
Number of
States
42
3
3
%
PWSs/Sites/Sam
pies with
detects
5.3
0
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
40
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.03
Not Detected
0.01
Median value of
Detects
0.086
90% of
Detects
1.5
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Cancer:
Notes
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
38 days
258
3.21
1.59E-05
375
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Esfenvalerate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 675 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Esfenvalerate
42403
66230044
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
325
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Maternal toxicity - abnormal gait and mobility
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
NC HRL/SW Chronic EEC: 26.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
rodent-rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C287,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Esfenvalerate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 676 of 1124
OCCURRENCE DATA
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
228,885
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
47
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 5.3 ug/L
Non-cancer: 26.4
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Ground water chronic: 0.009 ug/L
Cancer:
nsecticide; medication (HSDB)
Value
16. 3 days
100,000-398,000
<1
2
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DFA
Notes
DFA = Degrades slow with acclimation (HSDB)
-------
Estragole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 677 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Estragole
6041
140670
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
1,230
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
decreased body weight, increased liver weight
increased liver enzymes, hematoloficla effects
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,,
5 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data, RfD eq, Smith et al 2002, Adbo et al abstract
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
rodent-rat; FCTXAV Food and Cosmetics Toxicoogy. (London, UK) V. 1-19, 1963-81. For publisher
nformation, see FCTOD7. Volume(issue)/page/year 14,603,1976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70,000
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Estragole
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 678 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flavoring agent; n PPCPs (HSDB)
Value
38 days
3.47
178
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Ethanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 679 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethanol
2462
64175
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1.43
100
3,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1976
Critical Effect
Behavioral - changes in motor activity (specific assay),
Behavioral - ataxia, Behavioral - antipsychotic
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, JPETAB Journal of Pharmacology and Experimental
Therapeutics. (Williams & Wllkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year 197,488,1976; human study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
Rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 32(3), 31, 1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3.34
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ethanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 680 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
n
PWSs/Sites/Sa
mples
2
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
%
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide; beverage/food additive; medication; solvent (HSDB); gasoline additive
Value
1
-0.31
5.00E-06
1,000,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Ethephon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 681 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethephon
25550
16672870
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018
0.005
0.005
0.05
1,250
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1983
Critical Effect
Diarrhea, urinary & bowel movements urgency,
stomach cramps
Plasma cholinesterase inhibition
blood
Brain and Coverings - recordings from specific areas of
CNS, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Related to Chronic Data - death
Prevalence Magnitude
10 8
HRL Ratio(s)
NCHRL/SW Chronic EEC: 18.8
Notes
Reference Dose
Reference Dose, Union Carbide, 1977a, Basis LEL, human, UF=100
Reference Dose
Reference Dose; Union Carbide, 1977, Basis LEL, human, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 8 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 48(8), 79,1 983
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
126
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethephon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 682 of 1124
OCCURRENCE DATA
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
5,407,986
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
32
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 6.7 ug/L
Non-cancer: 18.8
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Ground water chronic: 0.67 ug/L
Cancer:
Plant growth regulator (HSDB)
Value
3.57
0.05
5.70E-12
1,000,000
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Ethion
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 683 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethion
7949
563122
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
0.0005
0.0005
0.0004
0.002
0.5
13
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
2000
1990
Critical Effect
Plasma, RBC & brain ChE inhibition
Decreased body weight
Brain acetylcholinesterase inhibition
Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase
Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3.5
Y/N
Y/N
W/L
W/L
Prevalence Magnitude , „
66 L
HRL Ratio(s)
NC HRL/SWC EEC: 0.53
Notes
Reference Dose; Basis = NOAEL 0.05 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 0.05 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level; Basis = NOAEL 0.06 mg/kg-d
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge
Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year 8,173,1988
Supplemental Data
PHJOAV Pharmaceutical Journa . (Pharmaceutcal Soc. of Great Britain, 1 Lambeth High St., London,
SE1 7JN, UK) V.131- 1933- Volume(issue)/page/year 185,361, 1960
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethion
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 684 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
Amount
Released
504,535
n
PWSs/Sites/Sa
mples
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0
Number of
States
2
%
PWSs/Sites/Sam
pies with
detects
0
0
Units
States
States
States
Minimum value of
Detects
Year
1997
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 6.6 ug/L
Non-cancer: 0.53
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Not Detected
Not Detected
Units
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)
Ground water chronic: 0 ug/L
Cancer:
nsecticide (HSDB)
Value
13,200
5.07
9.56E-07
2
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
-------
Ethyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 685 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethyl acetate
6103
141786
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.9
0.9
25
900
4,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1986
Critical Effect
Mortality & body weight loss
mortality and weight loss
Behavioral - somnolence (general depressed activity),
Behavioral - changes in motor activity (specific assay),
Behavioral - coma
Prevalence Magnitude , 0
8 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1986, Basis NOEL=900 mg/kg-d, rat, UF=1,000
Reference Dose
Reference Dose; UF = 1,000; USEPA1986; rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnay
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
6,300
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 686 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; food additive; solvent; medication (HSDB)
Value
6.13
0.73
0.000134
80,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Ethyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 687 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethyl acrylate
6050
140885
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
71.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Gastrointestinal - other changes
Prevalence Magnitude ,
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rat study; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0540988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.048
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol. 39, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
167
0.729
Y/N
Y/N
W/L
W/L
RAISHE; IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 688 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
249
152,024
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
24
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer additive; former food and PPCP additive (HSDB)
Value
11.9
1.32
0.00034
15,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
Ethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 689 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylamine
2620
75047
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
71.4
400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Gastrointestinal - other changes
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year
OTS0540988
Supplemental Data
Lewin, F.J. Saxs, Dangerous Properties of Industiral Materials. 9th ed. Volumes 1-3. New York,
NY:Van Norstrand Reinhold, 1996., pi 1517, LD50, rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 690 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
20
-0.13
1,000,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
Ethylene glycol monobutyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 691 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylene glyco monobutyl ether
4970
111762
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
0.5
0.07
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1998
Critical Effect
Changes in blood mean corpuscular volume (MCV)
changes in mean corpuscular volume
Prevalence Magnitude ,,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; NT, 1993, BMD, rat, UF=10
Refernce Dose
Reference Dose.NTP, 1993, BMD, mouse, rat, UF=10
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3,500
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethylene glycol monobutyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 692 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n hydraulic fluids; industrial solvent; in PPCPs (HSDB)
Value
1
0.83
1.60E-06
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Ethylenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 693 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylenediamine
4594
107153
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.09
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
iverand kidney toxicity
Prevalence Magnitude , „
87 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Hermanskyet al 1999; Basis NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
630
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethylenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 694 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; ndustrial solvent; in prep of dyes, synthetic waxes, resins, insecticides; veterinary medicine (HSDB)
Value
24.7
-2.04
1.73E-09
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Ethylenediaminetetraacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 695 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylenediaminetetraacetic acid
2393
60004
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
250
30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1966
1991
Critical Effect
NOAEL without a LOAEL
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,,,
67 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Oser et al. 1 966
Lowest Observed Adverse Effect Level
Supplemental Data
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park,
Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year 29,845,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,750
Y/N
Y/N
W/L
W/L
Teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ethylenediaminetetraacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 696 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; antioxidant; chelating agent; in PPCPs; veterinary medicine (HSDB)
Value
98
-3.86
7.70E-16
1,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Fenbutatin oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 697 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fenbutatin oxide
22779
13356086
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.017
0.03
15
1,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1991
Critical Effect
Decreased pup body weight gain
Blood - changes in leukocyte (WBC) count
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
95 L'
HRL Ratio(s)
No water data
Notes
Reference Dose; May 31 2002 certified letter to the registrant
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1219,2001
Supplemental Data
rodent, mouse; PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd.,
Thornton Heath CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,364,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
119
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Fenbutatin oxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 698 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
265,275
0
1,158
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
23
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Acaricide (HSDB)
Value
5.2
2.00E-09
0.0127
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Ferbam
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 699 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ferbam
24121
14484641
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.003
25
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1956
Critical Effect
Developmental Neurotoxicity
Behavioral - convulsions or effect on seizure threshold,
Related to Chronic Data - death
Prevalence Magnitude , „ ,
9 6 L"L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose, OPP RED Fact Sheet RfD for Thiram
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Group ADI for Ferbam and Ziram
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in dog; JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 118,174,1956
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
105
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Ferbam
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 700 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
317,125
0
0
OPP Estimated Environmental Concentration
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
24
0
0
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 0 ug/L
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 0 ug/L
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Cancer:
Fungicide (HSDB)
Value
300
-1.6
130
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
Fluometuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 701 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fluometuron
12839
2164172
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0055
0.013
0.01
0.013
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased body weight gain and discoloration in the
spleen.
No adverse effects. Decreased Potency Score by one
nteger
Endocrine - changes n spleen weight, Blood - changes in
spleen, Nutritional and Gross Metabol c - weight loss or
decreased weight gain
Prevalence Magnitude , „ ,
95 L' L
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 19.25
CAR HRL/NAWQA AW 90% : 0.97
Notes
Reference Dose
Reference Dose, NCI, 1980, NOAEL 12.5, rat, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB80-21 7904
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
0.018
c
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
OPP
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.5
38.5
1.94
Y/N
Y/N
mg/L
M/L
M/L
EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Reative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Fluometuron
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 702 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA AW 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,,2, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,600
^Samples
Amount
Released
5,313,290
1,736
1,776
n
PWSs/Sites/Sa
mples
345
130
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
24
19
2.83
% Samples with
detects
Number of
States
15
1
3
%
PWSs/Sites/Sam
pies with
detects
7.7
8.4
0.003
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0018
Non-cancer: 19.25
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
37.8
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.0105
0.264
0.1
0.22
Median value of
Detects
2
90% of
Detects
8.34
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
0.145
0.062
Units for Mag
data
ug/L
ug/L
ug/L
Cancer: 0.97
Notes
Pesticide Data Program (USDA); 2002
Pesticide Pilot Monitoring Program (USGS/EPA) raw water,
9060(HPLC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) finished water,
9060(HPLC/MS)
Herbicide (HSDB)
Value
363
2.42
1.80E-09
110
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Fluoroacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 703 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fluoroacetic acid
6203
144490
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00002
0.468
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Increased heart weight, decreased testes weight and
spermatogenisis - Sodium salt This is essentially the
same as sodium fluoroacetate
Prevalence Magnitude , „ ,
5 5 Li~L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R. J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van
Nostrand Reinhold, 1996., p. 1671
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Fluoroacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 704 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former rodenticide (HSDB)
Value
500
0.03
50
38
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Fomesafen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 705 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fomesafen
62548
72178020
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
9 7
Critical Effect
3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.19
C
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)-1
1988
adenoma and carcinoma; liver
Huntingdon, 1985; mouse study
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.184
Y/N
Y/N
W/L
W/L
RAISHE; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Fomesafen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 706 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
1,100,341
2,342
42,651
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
24
2
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (HSDB)
Value
6-12 months
11,000
2.9
7.54E-13
50
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)
-------
Fonofos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 707 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fonofos
10236
944229
Attribute Scores
Potency Severity
6 5
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
0.002
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
RBC ChE inhibition, cholinergic symptoms (tremors,
acrimation, salivation), increased liver weight
RBC ChE inhibition, cholinergic symptoms (tremors,
acrimation, salivation), increased liver weight
3-model Categorical Prediction
NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 31 1
Notes
Reference Dose
Reference Dose, Stauffer Chemical Co, 1969, NOEL 0.2, dog, UF=100
Reference Dose
Reference Dose, Stauffer Chem
cal Co, 1969, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.07
14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Fonofos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 708 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,116
# Sam pies
Amount
Released
417,372
n
PWSs/Sites/Sa
mples
283
669
3
95
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
1.3
1.34
% Samples with
detects
Number of
States
33
/O
PWSs/Sites/Sam
pies with
detects
0.1
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0075
0.04
Non-cancer: 311
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.2
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.0075
0.007
Median value of
Detects
0.045
90% of
Detects
0.21
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2002(GC/MS)
Cancer:
Restricted use insecticide; fumigant (HSDB)
Value
38 days
864
3.94
6.97E-06
15.7
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Formetanate hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 709 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Formetanate hydrochloride
27710
23422539
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00065
18
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1979
Critical Effect
Cholinesterase inhibition in the pup brain
Prevalence Magnitude , „ ,
10 5 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 56.9
Notes
Reference Dose; IRED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
mouse; Worthing, C. R. (ed.). Pesticide Manual. 6th ed. Worcestershire, England: British Crop Protection
Council, 1979., p. 284
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4.55
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Formetanate hydrochloride
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 710 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
134,527
# PWSs/Sites
sampled
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
27
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Surface water chronic: 0.08 ug/L
Non-cancer: 56.9
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Notes
Ground water chronic:
Cancer:
nsecticide (HSDB)
Value
3.2-212
2.30E-19
>500,000
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Formic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 711 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Formic acid
2463
64186
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2
360
700
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1921
1979
Critical Effect
Decreased growth
Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain
Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 16,463,1921
Supplemental Data
rodent, mouse; GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For
publisher information, see MTPEEI Volume(issue)/page/year 23(12), 49, 1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14,000
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Formic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 712 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
240,191
10,144,003
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
22
38
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; chemical intermediate; pesticide; in pa nt strippers (HSDB)
Value
1
-0.54
1.67E-07
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Furan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 713 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furan
4814
110009
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.001
21.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1993
Critical Effect
Minimal to mild liver lesions. Increased relative liver
weight
iver
Liver - other changes, Liver - changes n liver weight,
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude , „
68 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NTP, 1982, NOAEL 2, mouse, UF=1000
Reference Dose
Reference Dose, NTP, 1982, NOAEL/LOAEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in mouse; NTPTR National Toxicology
Program Techn cal Report Series. (Research Tr angle Park, NC 27709) No.206-
Volume(issue)/page/year NTP-TR-402,1993
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Furan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 714 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
89.7
1.34
0.00541
10,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (HSDB)
-------
Furfural
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 715 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furfural
3927
98011
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.003
53.6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1990
Critical Effect
Mild hepatocellular vacuolization
iver
Liver - changes in liver weight
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NTP, 1981a, LOAEL 11, rat. UF=3000
Reference Dose
Reference Dose, NTP, 1981, LOAEL, rat. UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in mouse; NTPTR National Toxicology
Program Techn cal Report Series. (Research Tr angle Park, NC 27709) No.206-
Volume(issue)/page/year NTP-TR-382,1990
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
21
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Furfural
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 716 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; flavoring; chemical intermediate (HSDB)
Value
17.7
0.41
3.38E-06
77,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Furfuryl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 717 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furfuryl alcohol
3826
96297
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4
75
930
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Hematological effects, increase in spleen relative and
absolute weights.
Endocrine - changes in spleen weight, Blood - pigmented
or nucleated red blood cells, Blood - changes in
erythrocyte (RBC) count
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
6 7 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientif c & Technical Information. Volume(issue)/page/year
OTS0524679; 13 week rat study
Supplemental Data
Rodent-rat; TSCAT Office of Tox c Substances Report. (U.S. Environmental Protection Agency, Office of
Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year OTS 513319
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
28
Y/N
Y/N
ug/L
ug/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Furfuryl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 718 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Antioxidant (ChemlDPIus); Industr
Value
0.63
1.04E-05
100,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
al chemical (EPA/SRS)
Degradation
Code
BS
Notes
BS = Biodegrades s ow (BIODEG)
-------
gam ma-Butyrolactone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 719 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
gam m a-Butyrolactone
3838
96480
Attribute Scores
Potency Severity
4 5
Prevalence Magnitude
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
175
262
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased respiration and activity in mice.
Hyperplasia of the adrenal medula (males) decreased
body weight gain (females). Cancer equivocal evidence
male mice. No evidence male or fema e rats and female
mice
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP Report 406
Lowest Observed Adverse Effect Level
Supplemental Data; NTP Report 406
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1999
Vol. 11, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,225
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
gam ma-Butyrolactone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 720 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent in PPCPs (HSDB)
Value
1 5 days
7.1
-0.64
5.30E-08
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Glutaraldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 721 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glutaraldehyde
4927
111308
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Liver - fatty liver degeneration, Nutritional and Gross
Metabolic - weight loss or decreased weight gain,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - true cholinesterase
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (VTO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue);pagefyear52(3),77,1987
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.7
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Glutaraldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 722 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; embalm ng fluid; chemical intermediate (HSDB)
Value
-0.18
1.10E-07
1,000,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Glycerine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 723 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glycerine
2289
56815
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
16
850
4,090
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
1977
Critical Effect
Skin and Appendages - tumors, Tumorigenic - facilitates
action of known carcinogen
Ql tract: hyperaemia, petechial haemorrhage or
erosions (DR)
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
8 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 25-week study in mouse. CALEDQ Cancer Letters (Shannon,
reland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
Volume(issue)/page/year 1 55,61 ,2000
Supplemental Data, SIDS
rodent, mouse; FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.3- 1930- Volume(issue)/page/year (6), 56,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,217
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Glycerine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 724 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; in PPCPs; food additive; in res ns (HSDB)
Value
-1.76
1.75E+11
1,220,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Glycidol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 725 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glycidol
7880
556525
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
19
150
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Effects on sperm count and testicular histopathology
Brain and Coverings - demyelination, Kidney, Ureter,
Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis) testicular atrophy, reduced
survival, Related to Chronic Data - death Clear evidence
of carcinogenicity in mice and rats 2 species and 2-sexes
Prevalence Magnitude
1 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP
Lowest Observed Adverse Effect Level
Supplimental Data, NTPTR National Toxicology Program Technical Report Series. (Research Triangle
Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-374,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
133
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Glycidol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 726 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; stabilizer (HSDB)
Value
1 5 days
-0.95
5.84E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Glyoxal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 727 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glyoxal
4600
107222
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
297
200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
decreased body weight gain
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - weight loss
or decreased weight gain, Biochemica - Enzyme
inhibition, induction, or change in blood or tissue levels -
other transferases
Behavioral - muscle weakness
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; IPCSCICAD2004
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 16,763,1991
Supplemental Data
rodent, rat; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0533618
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,400
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Glyoxal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 728 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n textiles; chemical intermediate (HSDB)
Value
1 5 days
1
-1.66
3.33E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
HCFC-133a
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 729 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
HCFC-133a
2690
75887
Attribute Scores
Potency Severity
Prevalence Magnitude
3 6
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol. 41,Suppl7, Vol71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
HCFC-133a
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 730 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
23
56,253
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Refrigerant; chemical intermediate (HSDB); gas
Value
38
30
0.27
9,200
47
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Heptane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 731 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Heptane
6156
142825
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2.86
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver -changes in liver weight
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issueXpage;yearOTS0571116
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
6.67
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Heptane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 732 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Gasoline standard; anesthetic, solvent, in organic synthesis (HSDB)
Value
275
4.66
2.00E+00
3.4
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Hexachlorobutadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 733 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexachlorobutadiene
3263
87683
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002
0.0002
0.0002
0.00034
2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
1965
Critical Effect
ncrease in urinary coproporphyrin excretion &
increase in renal tubular epithelial
hyperplasiafproliferation
regeneration
kidney
Liver - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol), Immunological
ncluding Allergic - increase in cellular mmune response
Prevalence Magnitude , „
45 L'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.28
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, USEPA, 1993; Basis LOAEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, .Yangetal., 1989, NTP1991, BMLD(50), mouse, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-week oral study in guinea pig; GTPZAB Gigiena Truda i
Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year 9(1 11,50,1965
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.05
0.078
C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1.4
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexachlorobutadiene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 734 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,284
22,736
43
41
0.35
0.18
0.05
0.1
10
1.5
0.25
0.3
5
0.8
10
1.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,310
# Sam pies
Amount
Released
5
742
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
3
% PWSs/Sites
with detects
0.14
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.28
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; chlorine gas scavenger; solvent; hydraulic fluids (HSDB)
Value
994
4.78
0.0103
3.2
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Hexachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 735 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexachloroethane
2514
67721
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.001
0.001
0.01
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Renal lesions, including renal atrophy, degeneration,
hypertrophy, & dilation
kidney, atrophy and degeneration of renal tubules
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Referenc Dose, Gorzinski et al., 1985, NOAEL 1 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose.Gorzinski et al., 1985, NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.3
0.014
0.039
C
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7
3
Y/N
Y/N
W/L
W/L
CACART; EPA; RAISHE; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 736 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,618
# Sam pies
Amount
Released
5
1,015
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
8
% PWSs/Sites
with detects
0.05
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame inhibitor/retardant; polymer additive; in organic synthesis (HSDB)
Value
10,600
5.2
1.00E-05
0.25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Hexahydro-1,3,5-tris(2-hydroxye
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 737 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine
16177
4719044
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1.99
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value - Dermal sensitization
Prevalence Magnitude
6 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231)
Volume(issue)/page/year #3824309
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexahydro-1,3,5-tris(2-hydroxye
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 738 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Bacteriocide (ChemlDPIus)
Value
38 days
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Hexahydroazepine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 739 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexahydroazepine
4944
111499
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
90
20.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Some discomfort on dosing
Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Liver - other changes
Prevalence Magnitude ,,, _
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPPT Summary, NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data
Rodent, rat; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0534842
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
630
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexahydroazepine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 740 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
170
6.10E-06
31,900
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Hexamethylene-1,6-diisocyanate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 741 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylene-1 ,6-diisocyanate
9801
822060
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Supplemental Data
LD50.TAKHAA Takeda Kenkyusho Ho. Journa of the Takeda Research Laboratories. (Takeda
Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970-
Volume(issue)/page/year 39,202,1980, rodent, mouse
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexamethylene-1,6-diisocyanate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 742 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer additive; adhesive; chemcal intermediate (HSDB)
Value
5,864
3.2
4.80E-05
117
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Hexamethylenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 743 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylenediamine
5553
124094
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
150
750
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1977
Critical Effect
2-generation study; reduced litter size, reduced
maternal and pup weights
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Short el a , 1991 , NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data
rodent, rat; TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth,
MN 55802) V.1- 1959- Volume(issue)/page/year 42,417,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,050
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Hexamethylenediamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 744 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
286
3.20E-09
2,460,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Hexamethylenetetramine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 745 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylenetetramine
4151
100970
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,234
569
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1970
Critical Effect
Yellow discoloration of fur
Behavioral - excitement, Behavioral - muscle contraction
or spasticity
Prevalence Magnitude ,,, „
7 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, Porta, 1965, LOAEL
Rodent, mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
35(3), 115,1970
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,879
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hexamethylenetetramine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 746 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Adhesives/coatings; medications; catalyst (HSDB)
Value
553
1.60E-09
667,000
98
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
HMX
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 747 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
HMX
13804
2691410
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.05
0.05
0.05
0.994
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1988
1997
1975
Critical Effect
Hepatic lesions
Hepatic lesions
Hepatic
Brain and Coverings - other degeneratve changes,
Behavioral - alteration of classical conditioning
Prevalence Magnitude ,,, „
3 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. DOD, 1985a; Basis NOAEL 50 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; U.S. DOD, 1985a; Basis NOAEL/LOAEL 50 mg/kg-d, rat, UF=1000
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 22-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/vear 40(1 1 ), 1 7, 1 975
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1989
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2
350
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
HMX
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 748 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Explosive (HSDB)
Value
38 days
1,853
0.82
8.66E-10
2,556
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Hydrochloric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 749 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrochloric acid
19106
7647010
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
1996
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
10 10
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1835, rabbit
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
Teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Hydrochloric acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 750 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in food processing (HSDB)
Value
14.3
0.54
0.0245
42,400
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Hydrocinnamic acid, 3,5-di-tert
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 751 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-,
methyl ester
17833
6386385
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - food intake (animal), Liver - other
changes, Blood -changes in leukocyte (WBC) count
Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 221 61) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0539881; 90-day rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,400
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hydrocinnamic acid, 3,5-di-tert
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 752 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate; in etching (HSDB - uses for 1,2-, 1,3- and 1,4-diethylbenzene)
Value
60 days
6
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
Hydrogen sulfide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 753 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrogen sulfide
19345
7783064
Attribute Scores
Potency Severity
6 3
Prevalence Magnitude
10
ncomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.03
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Gastrointestinal disturbance. RfD withdrawn in IRIS
2003. Questionable study.
3-model Categorical Prediction
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Watterau etal., 1964, NOAEL, pig, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
21
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hydrogen sulfide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 754 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; disinfectant (HSDB)
Value
14.3
-1.38
0.00869
3,740
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Hydroquinone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 755 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydroquinone
5502
123319
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
35.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Hematological effects
Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - multiple enzyme effects
Prevalence Magnitude
8 8 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Carlson and Brewer, NOAEL, human, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 23,397,1994
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.056
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
280
0.625
Y/N
Y/N
W/L
W/L
RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hydroquinone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 756 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
11,265
574,933
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
14
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Photographic chemical; antioxidant; chemical intermediate; medication (HSDB)
Value
434
0.59
4.72E-11
72,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Hydroxyethyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 757 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydroxyethyl methacrylate
9951
868779
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
2.5
3,275
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1989
Critical Effect
Decreased relative organ weight
Liver - other changes, Blood - changes in spleen
Behavioral - coma
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 35-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 52(11), 81, 1987
Supplemental Data
Rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 54(9), 75,1989
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Hydroxyethyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 758 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10M-50M
>10M-50M
Polymer intermec
Value
43
0.47
4.60E-09
1,000,000
39
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Iron pentacarbonyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 759 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
ron pentacarbonyl
22932
13463406
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
12
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Nanomaterial - no information provided
Prevalence Magnitude , „ ,
2 6 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1946, rabbit
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Iron pentacarbonyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 760 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
43,51 r
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Gasoline additive; chemical intermediate (HSDB)
Value
3
50-100
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Isobutanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 761 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutanol
2836
78831
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
3
1,022
74.1
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1984
Critical Effect
Hypoactivity & ataxia
Behavioral - somnolence (general depressed activity),
Nutritional and Gross Metabolic - changes in potassium,
Related to Chronic Data - death
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „, „ , „
8 7 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S.EPA, 1986, NOEL 316 mgrtsg-d, rat, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS0531 063
Supplemental Data
VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. etal., Chimia,
1 994. Volume(issue)/page/year -, 1 02, 1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,100
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Isobutanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 762 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; solvent; flavoring (HSDB)
Value
2.05
0.76
9.79E-06
85,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Isobutene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 763 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutene
5093
115117
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
10 8
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Some evidence of carcinogenicity in male rats (NTP)
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isobutene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 764 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units
Cancer:
Notes
Chemical intermed ate; octane enhancer; in polymers (HSDB)
Value
15
450
2.34
0.218
263
88
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Isobutyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 765 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutyl acetate
4829
110190
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4,763
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
1972
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
75 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rodent-rabbit; IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.1 8-42, 1949-73. For
publisher information, see IOHSA5. Volume(issue)/page/year 41,31, 1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isobutyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 766 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; so vent (HSDB)
Value
200
1.78
0.00045
6,300
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Isobutyronitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 767 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isobutyronitrile
2835
78820
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
55 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1960, mouse
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isobutyronitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 768 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; gasoline additive (HSDB)
Value
42
0.46
5.39E-05
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Isooctyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 769 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sooctyl acrylate
30980
29590429
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Behavioral -somnoence (general depressed activity),
Behavioral - ataxia, Gastrointestina - hypermotility,
diarrhea
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave.,
NW, Washington, DC20005) V.1- 1975/76- Volume(issue)/page/year34,297,1991, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isooctyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 770 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemical (EPA/SRS)
Value
1 5 days
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Isophthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 771 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isophthalic acid
5410
121915
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
250
10,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Kidney effects - crystalluria, mild hydronephrosis,
pelvic calcification
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, 0 , „
8 7 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Sid assessment
Lowest Observed Adverse Effect Level
Supplemental Data
rodent-rat; 85JCAE "Prehled Prumyslove Toxikoogie; Organicke Latky," Marhold, J., Prague,
Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year -,317,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,750
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isophthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 772 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical and polymer intermediate (HSDB)
Value
1 5 days
72
1.66
2.90E-13
130
27
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Isoprene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 773 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isoprene
2833
78795
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2.49
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgftg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1959
Critical Effect
Behavioral - alteration of classical conditioning
Prevalence Magnitude , „ ,
88 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WOMezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year24(6),8,1959
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
5.81
Y/N
Y/N
M8/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isoprene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 774 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n synthesis of rubber and natural products (HSDB)
Value
1 5 days
490
2.42
0.077
642
89
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Isopropanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 775 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isopropanol
2509
67630
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
BMDL
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
407
18
4.5
3,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1993-1994
Critical Effect
Decrease in male mating index.(another study- Gentry,
et al. give 500mg/kg NOAEL and also add decreased
fetal body weight).
Endocrine - effect on menstrual cycle; Reproductive -
Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Behavioral - altered sleep time (including change in
righting reflex), Behavioral - somnolence (general
depressed activity); AND Behavioral - general anesthetic
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data (Benchmark Dose), BMDL10, Shipp et al. 1996
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 122-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia
Supplemental Data
mouse; Clayton, G. D., F. E. Clayton (eds.) Patty's Industrial Hygiene and Toxicology. Volumes 2A, 2B,
2C, 2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994, p. 2630
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
11 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 43(1), 8,1 978; AND VCVGK "Vrednie
chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous
substances. Ga ogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.
Volume(issue)/page/vear -, 97,1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
2,849
Y/N
Y/N
W/L
W/L
teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Isopropanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 776 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; food additive; solvent (HSDB)
Value
1.06
0.05
8.10E-06
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Isopropyl formate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 777 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isopropyl formate
8937
625558
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1969
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
5 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
28ZEAL "Pesticide Index," Frear, E.H., ed.( State College, PA, College Science Pub., 1969
Volume(issue)/page/year 4,256,1969, rodent-guinea pig
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isopropyl formate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 778 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fumigant; chemica intermediate (HSDB)
Value
1 5 days
18
0.000775
20,700
49
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Isopropylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 779 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sopropylamine
2645
75310
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
111
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea,
Gastrointestinal - other changes
Prevalence Magnitude , „ ,
88 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear OTS054201 1 , rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Isopropylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 780 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate (HSDB)
Value
30
0.26
1,000,000
49
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
Kodaflex txib
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 781 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Kodaflex txib
18352
6846500
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
7 5
Critical Effect
Increased liver weight; Increase in grade of change of
renal tubular epithe ium and hyaline droplet
degeneration.
3-model Categorical Prediction
NL"7 - L"7
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Kodaflex txib
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 782 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Plasticizer in food packaging (ChemlDPIus)
Value
38 days
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Lactofen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 783 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lactofen
65964
77501634
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.008
0.002
0.002
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Kidney lesions and weight changes to the thyroid and
adrenal glands
ncr. abs./rel. liver weight; hepatocytomegaly-M
ncreased absolute and relative weight; hepatocytomegaly
in males
Prevalence Magnitude , „ ,
10 6 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 4,667
Notes
Reference Dose
Reference Dose, PPG Industries, 1985a, LEL 1.5 mg/kg-d, mouse, UF=1000
Reference Dose
Reference Dose, PPG Industries, 1985a, LEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
56
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Lactofen
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 784 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
# Sam pies
Amount
Released
389,388
0
0
n
PWSs/Sites/Sa
mples
115
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
26
0
0
%
PWSs/Sites/Sam
pies with
detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Maximum
value of
Detects
Year
1997
2002
2002
Maximum
value of
Detects
Surface water chronic: 0.012 ug/L
Non-cancer: 4,667
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Notes
Pesticide Data Program (USDA) 2002
Ground water chronic:
Cancer:
Herbicide (HSDB)
Value
25,400
4.81
5.73E-10
0.1
3
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Lactonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 785 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lactonitrile
2849
78977
Attribute Scores
Potency Severity
5 4
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6
31
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver cell enlargement or alteration, Blood- signif
decreases in GOT and signif increases in total protein,
albumin, and Ca. Swelling of Liver.
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
male'
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
42
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Lactonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 786 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1994
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate (HSDB)
Value
9 min
1
-0.94
9.80E-06
1,000,000
45
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
lambda-Cyhalothrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 787 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
lambda-Cyhalothrin
67650
91465086
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
56
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Decreased maternal weight gain during pregnancy;
decreased neonatal weight gain during weaning
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „ ,
10 6 L"L
HRL Ratio(s)
NC HRL/SWC EEC: 357
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,203,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
lambda-Cyhalothrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 788 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP
# Sam pies
Amount
Released
321,284
n
PWSs/Sites/Sa
mples
0
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
43
/o
PWSs/Sites/Sam
pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.098 ug/L
Non-cancer: 357
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Pesticide Pilot Monitoring Program (USGS/EPA) 9002(GC/MS)
Ground water chronic: 0.01 2 ug/L
Cancer:
nsecticide (HSDB - data for cyhalothrin, CASRN 68085-85-8)
Value
7
1.35E-05
8,530
1
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Lead acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 789 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lead acetate
11430
1335326
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude ,
5 10 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.038
B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
From OEHHA
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.921
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Lead acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 790 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Analytical reagent (HSDB)
Value
-4
250,000
Units
ength of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Linuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 791 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Linuron
6584
330552
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.008
0.002
0.002
4.93
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1975
Critical Effect
Decreased RBC count, hematocrit& hemoglobin levels
Abnormal blood pigment
Abnormal blood pigment
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other Enzymes
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 21 5
Notes
Reference Dose; du Pont, 1962
Reference Dose
Reference Dose; du Pont, 1962; Basis LEL 0.625 mg/kg-d, dog, UF=300
Reference Dose; du Pont, 1962; Basis LEL, dog, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 31-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(7), 46,1 975
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
1989
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
56
Y/N
Y/N
W/L
W/L
Developmental
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Linuron
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 792 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
298
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,142
# Sam pies
Amount
Released
516,133
0
11
n
PWSs/Sites/Sa
mples
154
339
# Sites
142
105
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
0
#with Detects
0
1.47
% Samples with
detects
Number of
States
35
0
2
%
PWSs/Sites/Sam
pies with
detects
0.3
0
% PWSs/Sites
with detects
0
0.0005
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Minimum value of
Detects
Not Detected
Non-cancer: 215
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.4
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Maximum
value of
Detects
Not Detected
0.03
Median value of
Detects
0.26
90% of
Detects
0.74
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA)2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001 (GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) 9060 (HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
60 days
350
3.2
6.26E-09
75
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Lithium carbonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 793 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lithium carbonate
7842
554132
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
404
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1998
Critical Effect
Brain and Coverings - recordings from specific areas
of CNS, Liver - liver function tests impaired, Blood -
pigmented or nucleated red blood cells
Peripheral Nerve and Sensation - flaccid paralysis with
appropriate anesthes a, Behavioral - tetany, Cardiac -
arrhythmias (including changes in conduction)
Prevalence Magnitude
87 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, STGNBT "Spravochnik po Toksikologii i Gigienicheskim
Normativam (PDK) PotentsiaPno Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B.
Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
Supplemental Data
VCVN1 "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp"
(Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
Volume(issue)/page/year -, 25,1 998
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
23.3
Y/N
Y/N
M8/L
W/L
Developmental
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Lithium carbonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 794 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
5
21 1 ,661
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
14
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Coatings; chemica intermediate; medication (HSDB)
Value
13,100
Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Lithium chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 795 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lithium chloride
18915
7447418
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.009
526
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1998
Critical Effect
Cardiac - pulse rate increase, without fall in BP, Liver -
iverfunction tests impaired, Blood - changes in
erythrocyte (RBC) count
Behavioral - tetany, Lungs, Thorax, or Respiration -
respiratory depression, Gastrointestinal - hypermotility,
diarrhea
Prevalence Magnitude
1
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; STGNBT "Spravochnik po Toksikologii i Gigienicheskim
Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B.
Gorshkova, eds. 46, ZhivopisnayaSt., 123182, Moscow, Russia, IzdAT 1999
Supplemental Data
VCVN1 "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp"
(Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
Volume(issue)/page/year -, 26,1 998
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.021
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Lithium chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 796 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; salt baths; dessicant; in welding (HSDB)
Value
832,000
Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Malathion
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 797 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Malathion
5402
121755
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.07
0.02
0.02
0.02
0.02
0.3
0.34
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
2001
Critical Effect
RBC ChE inhibition
Red blood cell cholinesterase inhibition
RDB ChE depression
cholinesterase inhibit on
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase
Prevalence Magnitude
9 3 NL
HRL Ratio(s)
NC HRL/NAWQA 90%: 5,698
Notes
Reference Dose, Moeller and Rider, 1962
Reference Dose, Moeller and Rider, 1962, basis NOEL 0.23 mg/kg-d, human, UF=10
Reference Dose
Reference Dose, Moeller and Rider, 1 962, basis NOEL/LEL, human, UF=1 0
Minimal Risk Level, Daly, 1996, basis NOAEL 2 mg/kg-d, rat, UF=100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 56-day oral study in human; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 1 ,59,2001
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
Y
0.8
490
0.19
Y/N
Y/N
mg/L
W/L
W/L
mg/L
teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Malathion
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 798 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,117
# Sam pies
Amount
Released
5,809,943
10,288
24,199
n
PWSs/Sites/Sa
mples
283
669
271
344
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
4.83
% Samples with
detects
Number of
States
42
2
8
/O
PWSs/Sites/Sam
pies with
detects
0
0
0.0015
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Non-cancer: 5,698
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
9.58
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
0.014
Median value of
Detects
0.086
90% of
Detects
0.39
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
Not Detected
99% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Cancer:
Insecticide; veter nary medicine (HSDB)
Value
11 days
30.5
2.36
4.89E-09
143
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Maleic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 799 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maleic anhydride
4681
108316
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.1
390
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1982
Critical Effect
Renal lesions
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose U.S. EPA, 1982, NOAEL 10mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, EPA 1983, NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rodent, guinea pig; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year -, 79,1 982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Maleic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 800 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,185
769,446
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
31
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; petroleum additive (HSDB)
Value
0.37 minutes
1
1.62
3.94E-06
4,912
35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Maleic hydrazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 801 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maleic hydrazide
5504
123331
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.25
0.5
0.5
0.5
0.3
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1996
Critical Effect
Decreased body weight gain
Kidney
Renal dysfunction
Prevalence Magnitude ,,, „
10 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Uniroyal Chemical, 1981, basis LEL 500 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; Uniroyal Chemical, 1981, basis LEL, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
20
1,750
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Maleic hydrazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 802 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,143,154
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
36
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (HSDB)
Value
10.4
-0.84
2.64E-11
4,510
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
Malononitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 803 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Malononitrile
4794
109773
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
5.86
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
hepatic effects
Liver - other changes, Kidney, Ureter, Bladder - other
changes
Prevalence Magnitude
2 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Lonza 1989, NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0526327
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Malononitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 804 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
854,039
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
s
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; petroleum additive (HSDB)
Value
15 days
15.3
-0.6
1.27E-08
133,00
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Maneb
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 805 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maneb
22381
12427382
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.005
0.005
0.03
0.05
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1977
1988
1993
Critical Effect
ncreased thyroid weight &follicular cell hypertrophy,
decreased T4
increased thyroid we ght
increased weight
thyroid
Prevalence Magnitude , „
10 8 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose, Rohm and Haas Co., 1977; Maneb Task Force, 1986,
Reference Dose, Rohm and Haas Co., 1977; Maneb Task Force, 1986, NOEL 5mg/kg-d, primate, UF=100
Reference Dose
Reference Dose; Maneb Task Force, 1986, NOEL/LEL, monkey, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, NOAEL, Ulrich, 1986 and 1987 as cited in JMPR, 1984, rat, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
350
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Maneb
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 806 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
3,039,930
0
335
OPP Estimated Environmental Concentration
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
43
0
1
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 0 ug/L
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 0 ug/L
Cancer:
Fungicide (HSDB)
Value
10
0.62
5.65E-07
6.2
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
MCPA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 807 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
MCPA
3709
94746
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0044
0.0005
0.0005
3.9
439
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1980
Critical Effect
Hepatotoxicity & nephrotoxicity
kidney, liver
Tumorigenic - carcinogenic by RTECS criteria, Blood -
eukemia
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude .,, „
6 5 NL--L-
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 45.29
Notes
Reference Dose
Reference Dose, Industry Task Force on MCPA, 1986a, Basis NOEL 0.15 mg/kg-d, dog, UF=300
Reference Dose
Reference Dose, Industry Task Force on MCPA, 1986a, Basis NOEL/LEL, dog, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 78-week oral study in mouse; TJEMAO Tohoku Journal of
Experimental Medicine. (Maruzen Co. Ltd., Export Dept, P.O. Box 5050, Tokyo Int., 100-31 Tokyo,
Japan) V.1- 1920- Volume(issue)/page/year 160,97,1990
Supplemental Data
RPZHAW Roczniki Panstwowego Zakladu Higieny. (Ars Polona, POB 1001, 00-068 Warsaw 1 , Poland)
V.1- 1950- Volume(issue)/page/year31, 373,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ
Y
0.02
30.8
2
Y/N
Y/N
mg/L
W/L
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
MCPA
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 808 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,548
# Sam pies
Amount
Released
5,360,932
0
221
n
PWSs/Sites/Sa
mples
163
285
1
20
44
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4
0
0.97
% Samples with
detects
Number of
States
31
0
3
%
PWSs/Sites/Sam
pies with
detects
1.4
0.4
0
0.006
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.012
Non-cancer: 45.29
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
18.6
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.012
0.17
Median value of
Detects
0.68
90% of
Detects
18.6
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 9060(HPLS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalconta
minants.aspx
Cancer:
Herbicide (HSDB)
Value
15 days
29.4
3.25
1.33E-09
630
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
m-Cresol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 809 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
m-Cresol
4686
108394
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.05
300
1,500
2,007
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased body weights & neurotoxicity
Decreased weight and neurotoxicity
Brain and Coverings - changes in brain weight, Liver -
changes in liver weight, Kidney, Ureter, Bladder - changes
in bladder weight
Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1986, 1987, NOAEL, rat, UF=1000
Reference Dose
Reference Dose, U.S. EPA, 1987, NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB92-1 74242
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
C
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
350
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
m-Cresol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 81 Oof 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
2,547
374,903
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
3
15
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
nsecticide; disinfectant; chemica
Value
434
1.96
8.56E-07
22,700
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ntermediate (HSDB)
Degradation
Code
BF/BFA
Notes
BF = Biodegrades fast/BFA = biodegrades fast with acclimat on (BIODEG)
-------
m-Dichlorobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 811 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
m-Dichlorobenzene
7698
541731
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.09
0.03
37
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
Critical Effect
Hepatic necrosis, porphyria
Endocrine - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol), Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - dehydrogenases
Prevalence Magnitude ,,, „
4 7 NL'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 70
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; DCTODJ Drug and Chemical Toxicology.
(Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year
18,201,1995
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3
630
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
m-Dichlorobenzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 812 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NGOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
20,429
24,119
51
62
0.25
0.26
0.03
0.1
22.4
15
1.1
0.6
9.1
2.8
22
15
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,353
# Sam pies
Amount
Released
377
1,939
n
PWSs/Sites/Sa
mples
11,938
29
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
0.67
% Samples with
detects
Number of
States
3
6
/O
PWSs/Sites/Sam
pies with
detects
0.01
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.64
Non-cancer: 70
Amount Range
>500K-1M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.1
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.64
0.017
Median value of
Detects
0.06
90% of
Detects
0.1
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.64
90% of
Detects
0.64
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Fumigant/insecticide; chemical intermediate (HSDB)
Value
38 days
434
3.53
0.00264
125
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Melamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 813 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Melamine
4717
108781
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
178
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1983
Critical Effect
Kidney, Ureter, Bladder chronic inflamation in females;
nephropathy- other changes at both doses - suvival
decreased at high dose (males) - Cancer positive for
males rats and negative forfemale rats and mice
Prevalence Magnitude , „
8 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue);page/yearNTP-TR-245,1983
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol73
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
415
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Melamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 814 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E> Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in resins; eather tanning (HSDB)
Value
-1.37
1.80E-14
3,240
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
Mepiquat chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 815 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Mepiquat chloride
27927
24307264
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.6
0.03
0.03
75
464
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1992
1991
Critical Effect
Impaired neurological function; vacuolization of the
renal distal tubules; increased hemosiderin functions
Sedation Stonodonic spasms, dec food intake & body wt
Blood - other changes, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
9 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; BASF Wyandotte Chemical 1977a; Basis NOEL 25 mg/kg-d, dog, UF=1000
Reference Dose
Reference Dose, BASF WyandotteChemical 1977, NOEL/LEL, dog, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in dog; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,3269,1992
Supplemental Data
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C241,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
4,200
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Mepiquat chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 816 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
182,576
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
16
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Plant growth regulator (HSDB)
Value
15 days
174
-2.82
4.31 E-1 2
500,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Mercaptoacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 817 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Mercaptoacetic acid
2522
68111
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
114
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/Kg
Date
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
ZHYGAM Zeitschrift fuer die Qesamte Hygiene und Ihre Qrenzgebiete. (VEB Verlag Volk und
Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955-
Volume(issue)/page/year 20,575,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Mercaptoacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 818 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Chemical intermed ate; electroplat
Value
27
0.09
1.90E-08
1,000,000
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Year
1998
2002
Maximum
value of
Detects
Year
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units
Cancer:
Notes
ng; plasticizer (HSDB)
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Merphos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 819 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Merphos
6275
150505
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00003
0.00003
170
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1962
Critical Effect
Ataxia, delayed neurotoxicity & weight loss
ataxia, delayed neurotoxicity, weight loss
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.05
Notes
Reference Dose
Reference Dose, Abou-Donia et al., 1980; Basis NOEL 0.1 mgftg-d, hen, UF=3000
Reference Dose
Reference Dose, Abou-Donia et al., 1980 , NOEL/LOAEL, hen, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 27(8), 97,1962
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.21
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Merphos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 820 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
9
12
# PWSs/Sites/
Samples
94
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
% Samples with
detects
Number of
States
1
1
% PWSs/Sites/
Sam pies with
detects
2.13
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
1.5
Non-cancer: 0.05
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
4.3
Median value of
Detects
90% of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
99% of Detects
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
2.9
90% of
Detects
4.02
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Cancelled herbicde (HSDB)
Value
8.7 days
62,400
7.67
2.27E-05
0.0035
6
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (PBT)
-------
Methacrylamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 821 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylamide
2883
79390
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
12.5
451
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
Decreased body weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, _
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger PI. 3, D-1000 Berlin 33, Fed. Rep.
Ger.) V.32- 1974- Volume(issue)/page/year 47,179,1981
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
87.5
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methacrylamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 822 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Polymer intermec
Value
15 days
40
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (OECD/SIDS)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Methacrylic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 823 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylic acid
2885
79414
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5
1,060
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1973
1976
Critical Effect
Behavioral - alteration of classical conditioning
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, 0 , „
8 5 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see H YSAAV.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)Jpage/year
38(8),13,1973
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translaton, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095Moscow, USSR) V.1- 1936- Volume(issue)/page/year 41(4), 6,1976
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
11.7
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of wa er consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methacrylic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 824 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Polymer intermediate for resins and coatings (HSDB)
Value
15
0.93
3.90E-07
89,000
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Methacrylonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 825 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylonitri e
5635
126987
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
0.001
7.5
60
64
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Transient increase in SGOT & SGPT (liver enzyme)
levels; liver enzyme changes
increased SGOT and SGPT levels
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, Pozzani et al., 1968, NOAEL 9 mg/m3. Dog, UF=3000
Reference Dose
Reference Dose, Pozzani, 1968, NOAEL/LOAEL.dog, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB97-1 76390
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methacrylonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 826 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603
# Sam pies
Amount
Released
0
89,330
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
0
3
% PWSs/Sites
with detects
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-500M
>10M-500M
Polymer intermec
Value
15 days
12.8
0.68
2.47E-04
25,400
49
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Methional
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 827 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methional
14647
3268493
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,580
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
Critical Effect
Sense Organs and Special Senses (Eye) - lacrimation,
Lungs, Thorax, or Respiration - dyspnea, Lungs,
Thorax, or Respiration -other changes
Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative
Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977-
Volume(issue)/page/year 42,77,2000, LD50 of 1.52 mL/kg converted to mg/kg using a density of
1.041 g/mL (Aldrich Chemical).
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methional
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 828 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Natural flavoring agent; (American Chemical Society/C&E News)
Value
1 5 days
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Methomyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 829 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methomyl
25598
16752775
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.025
0.025
0.025
0.02
0.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1989
Critical Effect
Histopathological effects in the kidney
kidney, spleen
kidney, spleen
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude
2 7 NLi
HRL Ratio(s)
NC HRL/NCOD R2 90%: 106
Notes
Reference Dose
Reference Dose, duPont 1968, NOEL 2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose, duPont 1968, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; JDGRAX Journal of Drug Research.
(National Organ zation for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969-
Volume(issueVoaae/vear 18.145.1989
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
E
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1988
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.9
175
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methomyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 830 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,659
18
0.1422
Not Detected
3
1.65
1.65
3
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,506
# Sam pies
Amount
Released
1,997,489
# PWSs/Sites
sampled
134
495
# PWSs/Sites/
Samples
4,611
17
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
#with Detects
1
0.377
% Samples with
detects
Number of
States
42
% PWSs/Sites
with detects
0
% PWSs/Sites/
Sam pies with
detects
0.02
0.0044
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Minimum value of
Detects
15
Non-cancer: 106
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.0
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Maximum
value of
Detects
15
0.22
Median value of
Detects
0.47
90% of
Detects
1.0
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Median value of
Detects
15
99% of
Detects
90% of
Detects
15
Units for Mag
data
Units for Mag
data
ug/L
Cancer:
Notes
2001
2002
9060 (HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Insecticide (HSDB)
Value
5 days
12.01
0.6
1.97E-11
58,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Methotrexate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 831 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methotrexate
2369
59052
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.00435
0.5
180
135
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
1981
1982
Critical Effect
Liver - hepatitis (hepatocellular necrosis), zonal
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.23
Y/N
Y/N
mg/L
W/L
W/L
Developmental; Teratogen
Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
No data for calcuating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; HPTLD9 Hepatology (Baltimore). (Williams & Wilkins Co.,
Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1981- Volume(issue)/pagefyear
14,906,1991; 6-week study in rat
Maximum Recommended Daily Dose (MRDD)
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Geneva: World
Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work).,
p. V26 275 (1981); Study in rat
Lowest Observed Adverse Effect Level; NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd.,
Tokyo, Japan) Volume(issue)/page/year 6,841,1982; Oral study in rat
CACART
CACART; UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Methotrexate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 832 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREG ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Focazio, etal., 2008
HRL Ratios (No data for calcuating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
26
Amount
Released
# PWS/Sites/
Samples
0
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
Number of
States
% PWS/Sites/
Samples with
detects
Not detected
Units
States
States
States
Minimum value of
Detects
Not detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not detected
Year
Maximum
value of
Detects
Not detected
Not detected
Not detected
Not detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not detected
90% of
Detects
Not detected
Units for Mag
data
ug/L
Notes
Raw drinking water monitoring; Focazio, etal, 2008. Sci. Tot. Env .,
402(2-3): 201 -21 6.
Cancer:
Pharmaceutical
Value
38
1
-1.85
1.50E-31
2,600
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades Slowly with Acclimation
-------
Methyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 833 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl acetate
2868
79209
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1
3,705
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1972
Critical Effect
Increased alkaline phosphatase; liver
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA 1986, NOEL, Increased alkaline phosphatase, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rabbit; IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher
nformation, see IOHSA5. Volume(issue)/page/year 41,31,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7,000
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 834 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; food additve; industrial solvent (HSDB)
Value
1 5 days
3.32
0.18
0.000115
243,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Methyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 835 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl acrylate
3829
96333
Attribute Scores
Potency Severity
4 1
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
149
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1964
Critical Effect
None observed
Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in bladder weight, Nutritional and Gross Metabolic - weight
oss or decreased weight gain
3-model Categorical Prediction
NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1987, NOEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year6,29,1964
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
1990
1999
Vol. 39, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl acrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 836 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603
# Sam pies
Amount
Released
728
206,487
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
5
20
% PWSs/Sites
with detects
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Polymer intermec
Value
6.42
0.8
0.000197
49,400
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate; in adhesive formulations (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Methyl carbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 837 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl carbamate
8351
598550
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
71.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood - leukemia, Tumorigenic - active as anti-cancer
agent
Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)Apage/yearPB88-168570/AS
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
1987
Vol. 12, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
167
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl carbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 838 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
1 5 days
10
-0.66
4.00E-08
691,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Methyl mercaptan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 839 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl mercaptan
2609
74931
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
61
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Prevalence Magnitude
10 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley &
Sons. New York, N.Y. (2001)., p. 688
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl mercaptan
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 840 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; natural gas additive (HSDB); gas
Value
14.3
0.78
3.13E-03
15,400
75
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Methyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 841 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl methacrylate
2958
80626
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1.4
1.4
0.05
0.357
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
1976
Critical Effect
None, Marginally significant increase in kidney to body
weight ratio. Decreased Potency Score by one integer
kidney
Brain and Coverings - other degeneratve changes, Liver -
other changes, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - transaminases
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Borzelleca et al., 1864, NOEL 136 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, Borzelleca et al., 1964, NOEL, rat, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 39-week oral study in rabbit; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year41(4),6,1976
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
E
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1997
1994
Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
9,800
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 842 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603
# Sam pies
Amount
Released
2,408
3,657,567
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
8
39
% PWSs/Sites
with detects
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value
10.14
1.38
0.000338
15,000
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Methylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 843 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylamine
2607
74895
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1390
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
INHTE5 Inhalation Toxicology. (Published by Taylor & Francis Health, 1 1 New Fetter Lane, London
EC4P4EEJV.1- 1989- Volume(issue)/page/year 2,29,1990
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 844 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ntermediate for accelerators, dyes, Pharmaceuticals, insecticides, tanning; fuel additive (HSDB)
Value
389
0.57
1.11E-05
1,250,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Methylcyclopentadienyl manganes
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 845 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylcyclopentadienyl manganese tricarbonyl
22045
12108133
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20T
8
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
1976
Critical Effect
Kidney, Ureter, Bladder - other changes in urine
composition, Blood - changes in serum composition
e.g. TP, bilirubin, cholesterol), Nutritional and Gross
Metabolic - weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AECTCV Archives of Environmental Contamination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issue)/page/year 23,473,1 992
Supplemental Data
TMMT "The Toxicology of Methylcyclopentadienyl Manganese Tricarbonyl," Witherup, S., et al.,
Cincinnati, OH, Univ. of Cincinnati, 1976 Volume(ssue)/page/year -,-,1976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
482
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methylcyclopentadienyl manganes
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 846 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Fuel additive (HSDB); gas
Value
3.7
29
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Methyleugenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 847 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyleugenol
3608
93152
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
0.0714
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
2001
Critical Effect
Increased liver weights, decreased body weight gain
Endocrine - changes in spleen weight, Blood - changes in
platelet count, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases
Prevalence Magnitude ,,,
1 3 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental NOEL, Abdo, et al. 2001. Food and Chemical Toxicology 39 (2001) 303-316.
Lowest Observed Adverse Effect Level; 1 4-week oral study in rat; FCTOD7 Food and Chemical
Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year39,303,2001
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
Y/N
Y/N
M8/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyleugenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 848 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10K-500K
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; flavorant; insect attractant (HSDB)
Value
34 hours
140
3.03
5.60E-06
500
19
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Methylglutaronitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 849 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylglutaronitrile
16055
4553622
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1969
Critical Effect
Behavioral - convulsions or effect on seizure
threshold, Behavioral - excitement, Lungs, Thorax, or
Respiration - cyanosis.
Prevalence Magnitude , „ ,
6 7 L"L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed. Rep. Ger.) V.I -25,
1951-75. Volume(issue)/page/year 19,225,1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methylglutaronitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 850 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; solvent (HSDB)
Value
15 days
10.7
-0.644
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Methyltrichlorosilane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 851 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyltrichlorosilane
2682
75796
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981-1982
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
8 5 L"L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G. D. and F. E. Clayton (eds.). Pattys Industrial Hygiene and Toxicology: Volume 2A, 2B,
2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2398
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Methyltrichlorosilane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 852 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
50M-10M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
rapid
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Metiram
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 853 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Metiram
20233
9006422
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.004
0.03
73.9
620
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993
2000
1980
Critical Effect
Decrease forelimb grip strength
Endocrine - changes in thyroid weight, Blood - changes in
erythrocyte (RBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
9 7 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Group ADI with MANCOZED, MANEB AND ZINEB
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; TOSCF2 Toxicological Sciences
(Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41 , Jan. 1 998-
Volume(issue)/page/year 54,481 ,2000
Supplemental Data
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1924- Volume(issue)/page/year 56(6),59,1980
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
28
Y/N
Y/N
W/L
W/L
Developmental
CACART
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Metiram
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 854 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
1,385,330
OPP Estimated Environmental Concentration
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
24
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
Surface water chronic: 0 ug/L
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 0 ug/L
Cancer:
Fungicide (HSDB)
Value
100,000
0.3
9.30E-18
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Metribuzin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 855 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Metribuzin
27143
21087649
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.013
0.025
0.025
0.025
0.617
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
ncreased absolute & relative thyroid weight, increased
T4, decreased T3 in blood.
Liver; kidney; body weight; mortality
Brain and Coverings - other degeneratve changes
Prevalence Magnitude
1 7
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 45.5
Notes
Reference Dose, Mobay Chemical, 1974a
Reference Dose, Mobay Chemical, 1974a, NOEL 2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 5-week oral study in rat; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volumefissuel/Daae/vear 30.209.1990
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
CADW MAC
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.9
80
91
Y/N
Y/N
W/L
W/L
W/L
Drinking Water Equivalent Level
Canadian Drink ng Water Maximum Acceptable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Metribuzin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 856 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
13,568
9
0.0663
0.1
2
1.1
2
2
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
Supplemental Water Data
PPMP
PPMP
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,165
# Sam pies
Amount
Released
3,320,231
24
847
# PWSs/Sites/
Samples
288
582
# PWSs/Sites/
Samples
# PWSs/Sites/
Samples
7,281
459
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
#with Detects
47
0
#with Detects
1
6.41
% Samples with
detects
Number of
States
48
2
3
% PWSs/Sites/
Sam pies with
detects
0.3
% PWSs/Sites/
Samples with
detects
14.6
0
% PWSs/Sites/
Samples with
detects
0.01
0.002
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.042
Minimum value of
Detects
Minimum value of
Detects
4
Non-cancer: 45.5
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
6.61
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.042
Maximum
value of
Detects
Maximum
value of
Detects
4
0.022
Median value of
Detects
0.24
90% of
Detects
2.26
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.042
Median value of
Detects
Median value of
Detects
4
99% of
Detects
0.042
95% of
Detects
0.004
90% of
Detects
4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:
Notes
2001
2002
Notes
2001 raw water (GC/MS)
2001 finished water (GC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Herbicide (HSDB)
Value
1,196
1.7
1.17E-10
1,050
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Molybdenum trioxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 857 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Molybdenum trioxide
11108
1313275
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
9 8
Scores based on parent Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased uric acid levels
(for molybdenum)
3-model Categorical Prediction
L?
HRL Ratio(s)
NCHRL/NIRS90%: 1.10
Notes
Reference Dose
Reference Dose, U.S. EPA, 2003
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Molybdenum trioxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 858 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
77
7.79
6.1
180
10
30
110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
36,579
2,102,324
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
18
36
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.10
Amount Range
10M-50M
Catalyst; chemica
Value
1,066
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
Scores based on parent (molybdenum)
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
intermediate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
N.N'-Diethylthiourea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 859 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N.N'-Diethylthiourea
4461
105555
Attribute Scores
Potency Severity
6 9
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
316
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1973
Critical Effect
Details of toxic effects not reported other than lethal
dose value
3-model Categorical Prediction
L?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(NCILB Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer
Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year NCI-E-C-72-3252,1 973)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Vol 79; 2001
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
M8/L
W/L
IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
N.N'-Diethylthiourea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 860 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rubber accelerator; corrosion inh bitor (HSDB)
Value
1 5 days
49
0.57
6.85E-08
4,555
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
N, N-Dimethylacetamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 861 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N, N-Dimethylacetamide
5644
127195
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.583
65
2
4,390
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1980
Critical Effect
decreased fetal body weights in the absence of
maternal toxicity
Liver - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
esterases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - transaminases
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data, Johannsen etal 1987
Lowest Observed Adverse Effect Level; 26 week rat study
Supplemental Data
Kennedy, GL Jr, Sherman H; Drug ChemToxicol9 (2): 147-70(1986); Prager, J.C. Environmental
Contaminant Reference Databook, Volume 1. New York, NY: Van Nostrand Reinhold; rat
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
455
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N, N-Dimethylacetamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 862 of 1124
OCCURRENCE DATA
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent (HSDB)
Value
9
-0.77
1.31E-08
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (HSDB)
-------
N,N-Dimethylethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 863 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N,N-Dimethylethanolamine
4658
108010
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
450
15
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
increased liver and kidney weights
Prevalence Magnitude
7 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP summary of tox literature. NOAEL 450 mg/kg/day (Smyth etal, 1951
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3,150
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
N,N-Dimethylethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 864 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Medication; chem
Value
-0.94
3.73E-07
1,000,000
40
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
u
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
cal intermediate; stabilizer (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Naled
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 865 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Naled
6448
300765
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
21.4
92
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1969
1990
Critical Effect
Brain ChE inhibition
Brain cholinesterase nhibition
ChE inhibintion
Nutritional and Gross Metabolic - body temperature
decrease, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Related to Chronic Data - death
Behavioral - tremor, Gastrointestinal - changes in structure
or function of salivary glands, Gastrointestinal -
hypermotility, diarrhea
Prevalence Magnitude , „
96 L
HRL Ratio(s)
NC HRL/SWC EEC: 25
Notes
Reference Dose
Reference Dose, Chevron Chem cal Co., 1984a, NOEL 0.2 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, Chevron Chem cal Co., 1984a, NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; RPZHAW Roczniki Panstwowego
Zakladu Higieny. (Ars Polona, POB1001, 00-068 Warsaw 1 , Poland) V.1- 1950-
Volume(issue)/page/year20,463,1969
Supplemental Data
Rat; ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann
Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year 1,90,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Naled
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 866 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
# Sam pies
Amount
Released
605,456
0
0
# PWSs/Sites/
Samples
14
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
16
0
0
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.56 ug/L
Non-cancer: 25
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.005 ug/L
Cancer:
nsecticide; veter nary medicine (HSDB)
Value
96.03
1.38
6.51 E-05
1.5
37
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Naphthalene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 867 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Naphthalene
3465
91203
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
0.02
0.6
60
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1970
Critical Effect
Decreased terminal body weight
Decreased mean terminal body weight in males
Neurol.
Endocrine - changes in adrenal weight
Prevalence Magnitude
7 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 17.5
Notes
Reference Dose
Reference Dose, BCL 1980, NOAEL 100 mgflsg-d; adjusted NOAEL 71 mg/kg-d, rat, UF=3000
Reference Dose
Reference Dose, BCL 1980, NOAEL/LOAEL, rat, UF=3000
Minimal Risk Level-lnt.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; BIOFX BIOFAX Industrial Bio-Test
Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year 16-
4/1970
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
C
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.7
140
Y/N
Y/N
W/L
W/L
Teratogen
CACART; IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Naphthalene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 868 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
13,452
22,926
159
176
1.18
0.768
0.03
0.07
906
90
1
0.736
8
3.1
900
73
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,310
85
# Sam pies
Amount
Released
17,809
3,456,696
# PWSs/Sites/
Samples
sampled
10,913
83
14
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
20
1.926
16.5
% Samples with
detects
6.31
1.35
Number of
States
41
53
% PWSs/Sites/
Samples with
detects
0.18
0.005
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.008
Non-cancer: 17.5
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
70
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
7
0.072
0.020
Median value of
Detects
0.135
0.9
0.7
90% of
Detects
43
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.88
90% of
Detects
4.07
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; chemical intermediate; moth repellant (HSDB)
Value
38 days
1,837
3.3
0.00044
31
13
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
n-Butyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 869 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
n-Butyl acetate
5537
123864
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
14,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1993-1994
Critical Effect
Paper by Davis et al, suggests that n-butanol data are
appropriate for the effects of n-butylacetate since n-
butylacetate are readily hydrolyzed to n-butanol. In an
inhalation study, there was some minor evidence of
gastric irritation from the n-butyl acetate.
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G.D., F.E. Clayton (eds.) Pattys Industrial Hygiene and Toxicology. Volumes 2A, 2B, ZC,
2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994., p. 2980
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
n-Butyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 870 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; flavoring additive; industrial solvent (HSDB)
Value
200
1.78
0.00028
14,000
33
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
n-Butyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 871 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
n-Butyl methacrylate
3916
97881
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
30
3.57
12,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1976
1976
Critical Effect
Spleen toxicity, decreased absolute and relative
weights of the spleen.
Brain and Coverings - recordings from specific areas of
CNS, Behavioral - alteration of classical conditioning, Liver
- other changes; Blood - pigmented or nucleated red blood
cells, Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - catalases
Details of toxic effects not reported other than lethal dose
value
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 39-week oral study in rat and rabbit; GISAAA Gigiena i
Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow,
USSR) V.1- 1936- Volume(issue)/page/year 41(4), 6,1976
Supplemental Data
Mouse; GISAAA Gigiena i Sanitariya.
Kniga, 113095 Moscow, USSR) V.1-
-or English translation, see HYSAAV. (V/O Mezhdunarodnaya
1 936- Vo ume(issue)/page/year 41 (4) ,6, 1 976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
n-Butyl methacrylate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 872 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-SOM
Polymer intermec
Value
8.7 days
880
2.88
0.00079
24
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Neopentyl glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 873 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Neopentyl glyco
5606
126307
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased liver weight; increased kidney weight
Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Neopentyl glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 874 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (Merck Index, 1983)
Value
0.16
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Nickel
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 875 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nickel
18829
7440020
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
Critical Effect
Decreased organ (kidney, liver & spleen) & body
weights
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.7
140
Y/N
Y/N
mg/L
W/L
W/L
1995
Teratogen
Prevalence Magnitude , „
98 L
HRL Ratio(s)
NCHRL/NIRS90%: 0.74
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; IRIS
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
OEHHA, Class A
Vol. 49; 1 997; Cancer classifications were used for screening, but no related quantitative cancer risk data
were identified for potency scoring.
IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Nickel
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 876 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
47
4.75
5
150
7.6
190
110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,298
Amount
Released
29,802
6,119,051
# PWSs/Sites
sampled
2,171
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
65.8
Number of
States
37
49
% PWSs/Sites
with detects
0.03
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.74
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
666
Year
2004
2004
Maximum
value of
Detects
2
6
29.7
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Use data are for n ckel sulfate: Steel making, catalysts, storage batteries, specialty chemica s, and specialty ceramics (HSDB); naturally-occurring
Value
389,900
Units
length of time
cm3/g
unitless
cm3/g
unitless
mg/L
Degradation
Code
BST
Notes
assume persistent; all use and env. fate data are for nickel sulfate; BST = biodegrades sometimes/recalcitrant
-------
Nickel compounds
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 877 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nickel compounds
44
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
10 10
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased body and organ weights
3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Rat chronic oral study, Ambrose et al, 1 976
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
1
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1990
Vol. 49
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
140
Y/N
Y/N
W/L
W/L
Teratogen
IARC
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Nickel compounds
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 878 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
170,937
34,676,669
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
45
52
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Electroplating; steel additives (HSDB)
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Niobium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 879 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Niobium
18830
7440031
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
316
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
hyperplasia and hyperkeratosis of the stomach
Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, OPPTS summary LOAEL 316 mg/kg/day ammonium niobium dioxylate oxide
pentahydrate.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
8.03E-13
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
22.1
Y/N
Y/N
W/L
W/L
RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Niobium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 880 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n alloys; in nuclear reactions (Merck Index, 1983)
Value
350
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Nitrilotriacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 881 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitrilotriacetic acid
5991
139139
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
1.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1979
Critical Effect
Increased incidence of nephritis & nephrosis,
hyperglycaemia
Kidney, Ureter, Bladder - other changes in urine
composition, Kidney, Ureter, Bladder - changes in bladder
weight, Nutritional and Gross Metabolic - changes in
calcium
3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data, Health Canada ADI
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 4-week oral study in rat; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year 17,137,1979
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0053
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol. 73
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
WHODWQ
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
200
70
Y/N
Y/N
W/L
W/L
W/L
CACART; IARC; OEHHA
Drinking Water Equivalent Level
World Health Organization Drink ng Water Quality Value
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
Nitrilotriacetic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 882 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
14,494
30,679
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chelating agent; in detergents (HSDB)
Value
8.7 days
<286
-3.8
59,100
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
Nitrofen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 883 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nitrofen
12291
1836755
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.17
49.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1983
Critical Effect
Neonatal effects
Liver - changes in liver weight
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.082
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1.19
0.427
Y/N
Y/N
M8/L
W/L
Prevalence Magnitude , „
1 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Toxicology Volume 29, Issue 1-2, December 1983, Pages 1-37;
Lowest Observed Adverse Effect Level; 2-year oral study in mammal; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year 10,427,1972
Supplemental Data
CACART; EPA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Nitrofen
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 884 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0
25,300
# PWSs/Sites
sampled
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
0
1
% PWSs/Sites
with detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2002
2002
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (NTP)
Value
4,400
5.534
6.74 E-05
0.7-1.2
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
code
BSA
Notes
BSA = biodegrades slowly with acclimation
-------
Nitromethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 885 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitromethane
2658
75525
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
12.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
Behavioral - alteration of classical conditioning, Blood •
changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition,
induction, or change in blood or tissue levels -
transaminases
Prevalence Magnitude
6 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/pagefyear32(9),9,1967; 26-week oral study in rabbit
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
2000
Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
29.2
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Nitromethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 886 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rocket fuel; industrial solvent (HSDB)
Value
15
-0.35
2.86E-05
111,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (HSDB)
-------
N-Methylolacrylamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 887 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Methylolacrylamide
10095
924425
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
12.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1989
Critical Effect
Behavioral - ataxia, Liver - changes in liver weight,
Related to Chronic Data - changes in testicularweight
Prevalence Magnitude .,,„,-,
8 5 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-352,1989
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)-1
1994
Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
29.2
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Methylolacrylamide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 888 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
1,121
12,306
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
3
13
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Monomer; proposed for use in sunscreen (HSDB)
Value
15 days
-1.81
9.45E-12
653,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
N-Nitroso-di-n-butylamine (NDBA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 889 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-di-n-butylamine (NDBA)
10094
924163
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0006
5.4
11
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1986
1987
Bladder, esophagus
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.006
Y/N
Y/N
W/L
W/L
Prevalence Magnitude
1 1 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
OEHHA incorrectly lists EPA cancer classification as "A."
CACART; EPA; OEHHA; RAIS; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitroso-di-n-butylamine (NDBA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 890 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
0
5
# PWSs/Sites/
Samples
131
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
Number of
States
0
1
% PWSs/Sites/
Samples with
detects
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
2004
2004
Maximum
value of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes
Cancer:
Research chemical (HSDB)
Value
15
642
2.63
1.32E-05
1,200
26
Units
days
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
PBT; BS = Biodegrades Slowly
-------
N-Nitrosomethylethylamine (NMEA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 891 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosomethylethylamine (NMEA)
21341
10595956
Attribute Scores
Potency Severity
8 8
Prevalence Magnitude
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
22
22
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.0016
Y/N
Y/N
W/L
W/L
3-model Categorical Prediction
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
IRIS
CACART; EPA; RAIS; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitrosomethylethylamine (NMEA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 892 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
21
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
Number of
States
% PWSs/Sites/
Samples with
detects
0
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes
Cancer:
Research chemical (HSDB)
Value
38
25
0.04
1.40E-06
300,000
52
Units
days
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
PBT; BSA = Biodegrades Slowly with Acclimation
-------
N-Nitroso-N-methylurea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 893 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-N-methylurea
9372
684935
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2.86
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
Critical Effect
Musculoskeletal - changes in teeth and supporting
structures
Prevalence Magnitude
1 1 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 16-week oral study in hamster; TOPADD Toxicologic Pathology.
(c/o Dr. F.A. de a Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, Ml
48106) V.6(3/4)- 1978- Volume(issue)/page/year 27,226,1999
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
120
B2
2A
mg/L
(mg/kg-d)-1
(mgftg-d)-1
(mg/kg-d)"1
1987
Vol. 17, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.000292
Y/N
Y/N
W/L
W/L
Teratogen
OEHHA; EPA; IARC; CACART
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
N-Nitroso-N-methylurea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 894 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
5
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Synthetic intermediate; potential anti-neoplastic (HSDB)
Value
15 days
18.55
-0.03
9.91 E-11
14,400
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Norflurazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 895 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Norflurazon
30023
27314132
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.04
0.04
8,000
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1977
Critical Effect
Increased cholesterol, absolute & relative liver weight
Liver; thyroid
Liver; thyroid
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 84.7
Notes
Reference Dose
Reference Dose; Sandoz-Wander, 1973; Basis NOEL 3.75 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; Sandoz-Wander, 1973; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat; 85ARAE "Agricultural Chemicals, "Thomson, W.T., 4vols., Fresno, CA, Thomson Publications, 1976/^
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
105
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Norflurazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 896 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
PPMP finished water
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,557
# Sam pies
Amount
Released
2,459,703
0
0
# PWS/Sites/
Samples
154
288
71
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
1.56
% Samples with
detects
Number of
States
30
0
0
% PWS/Sites/
Samples with
detects
0
0.004
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 84.7
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
44
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
0.21
Median value of
Detects
1.24
90% of
Detects
26.5
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA)
Cancer:
Herbicide (HSDB)
Value
60 days
5,674
2.3
3.43E-10
33.7
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
o-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 897 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Chloronitro benzene
3327
88733
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
88.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
methemoglobinemia
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - weight loss
or decreased weight gain
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Bio/Dynamics, Inc. 1985; Basis NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 27-week oral study in mouse; NTIS National Technical
nformation Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical
nformation. Volume(issue)/page/year PB92-187608/AS
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0097
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1996
Vol65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7
Y/N
Y/N
W/L
W/L
RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
o-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 898 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
315.5
2.24
9.30E-06
441
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
o-Chlorotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 899 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Chlorotoluene
3764
95498
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.02
0.02
570
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1981
Critical Effect
Decreased body weight gain
Decreased body weight gain
Liver - liver function tests impaired, Kidney, Ureter,
Bladder - renal function tests depressed, Blood - other
changes
Prevalence Magnitude ,,, „
3 6 NL'
HRL Ratio(s)
NC HRL/NCOD R2 90%: 46.7
Notes
Reference Dose
Reference Dose; Gibson et al., 1974a Basis NOAEL 20 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; Gibson et al., 1974a Basis NOAEL/LOAEL 20 mg/kg-d, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(2), 67,1 981
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.7
140
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
o-Chlorotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 900 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
15,721
24,118
32
34
0.204
0.141
0.06
0.3
16.4
52.4
0.57
0.68
3
4.4
16.4
52.4
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
# Sam pies
Amount
Released
# PWS/Sites/
Samples
11,883
19
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
6
0.441
% Samples with
detects
Number of
States
% PWS/Sites/
Samples with
detects
0.05
0.004
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.6
Non-cancer: 46.7
Amount Range
>10M-50M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.356
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
24
0.0195
Median value of
Detects
0.05
90% of
Detects
0.356
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
7.9
90% of
Detects
17.5
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Solvent; chemica intermediate; insecticide (HSDB)
Value
443
3.42
0.00357
374
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
Octamethylcyclotetrasiloxane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 901 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Octamethylcyclotetrasiloxane
7887
556672
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,540
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral -tremor
Prevalence Magnitude .,, „
8 5 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0538262
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
108
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Octamethylcyclotetrasiloxane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 902 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in PPCPs; food additive; in fermentation (HSDB)
Value
38 days
14,000
5.1
0.117
0.005
10
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
o-Dianisidine dihydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 903 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Dianisidine dihydrochloride
26927
20325400
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
33
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Blood - other changes, Liver - changes in liver weight,
Kidney, Ureter, Bladder - changes in bladder weight
Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issueypagefyear NTP-TR-372,1990.
39 week study in rat.
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
77
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
o-Dianisidine dihydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 904 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
29
46
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Biochemical reagent (SigmaAldrich - manufacturer)
Value
38 days
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
o-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 905 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Dinitrobenzene
7498
528290
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased spleen weight
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Cody etal. 1981; Basis NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1992
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.7
Y/N
Y/N
W/L
W/L
Reproductive
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
o-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 906 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
102,329
105,280
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
225
1.69
3.69E-07
500
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
o-Nitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 907 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Nitrotoluene
3326
88722
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
37.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
2003
Critical Effect
Blood- elevated methemoglobin, anemia. Spleen- splenic
hemosiderosis, splenomegaly, splenic histopathology
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude , „
6 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA 1986; Basis LOAEL, rat, UF=10000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 15-week oral study in rat; TXCYAC Toxicology. (Elsevier
Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ire and) V.1- 1973- Volume(issue)/page/year
183.221.2003
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.23
3
mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1996
Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
70
0.15
Y/N
Y/N
W/L
W/L
CACART; RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
o-Nitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 908 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for petrochemicals, pesticides, dyes and Pharmaceuticals. n(HSDB)
Value
315.5
2.3
1.25E-05
650
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
o-Toluidine hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 909 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Toluidine hydrochloride
9161
636215
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver - other changes, Liver - changes n liver weight,
Related to Chronic Data - changes in testicular weight;
Kidney, Ureter, Bladder - changes in bladder weight,
Endocrine - changes in spleen weight, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain
Prevalence Magnitude
2 1 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week and 13-week oral study in rat; NTPTR National
Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. 206-
Volume(issue)/page/yearNIH-96-3936
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.18
0.13
B2
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
700
0.27
Y/N
Y/N
W/L
W/L
CACART; RAISHE; OEHHA; EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
o-Toluidine hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 91 Oof 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
22
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Dye intermediate (HSDB)
Value
15 days
74.04
1.32
1.98E-06
16,600
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Oxadiazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 911 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Oxadiazon
26706
19666309
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0036
0.005
0.005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
ncreased level of serum protein increased liver weight,
incidence of swollen cells in central lobe of the liver.
ncr. serum proteins; ncr. liver weights
ncreased levels of serum protein and increased liver
weight
3-model Categorical Prediction
NL?
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose; OPP
Reference Dose; Rhone-Poulenc, 1981; Basis NOEL 0.5 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Rhone-Poulenc, 1981; Basis NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.071 1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
25.2
0.49
Y/N
Y/N
W/L
W/L
Reproductive
CACART; EPA
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Oxadiazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 912 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data
POP
POP
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
28,822
# PWS/Sites/
Samples
154
317
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWS/Sites/
Samples with
detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Cancer:
Herbicide (HSDB)
Value
3,500
4.8
7.27E-08
0.7
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
Ozone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 913 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ozone
20667
10028156
Attribute Scores
Potency Severity
Prevalence Magnitude
9 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Ozone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 914 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
715,830
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
20
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Air and water dis nfectant; chemica intermediate (HSDB); Naturally-occurring gas
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
p,p'-DDE
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 915 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p,p'-DDE
2587
72559
Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.0005
12
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1984
2000
1996
Critical Effect
Liver - changes in liver weight, Immunological Including
Allergic - decrease in cellular immune response,
mmunological Includ ng Allergic - decrease in humoral
immune response
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
NC HRL/UCMR 90%: 0.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.01
0.34
0.34
B2
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1988
IRIS
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.1
Y/N
Y/N
W/L
W/L
CACART; EPA; RAISHE; OEHHA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
p,p'-DDE
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 916 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,867
1
0.0259
3
3
3
3
3
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
POP
PPMP
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,117
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
2,672
288
688
457
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
6
6.42
% Samples with
detects
Number of
States
% PWSs/Sites/
Sam pies with
detects
0
2.6
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer: 0.03
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.062
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
0.006
0.002
Median value of
Detects
0.0095
90% of
Detects
0.025
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Prgram (USGS/EPA) 2001(GC/MS)
Product of degradation of DDT (HSDB)
Value
180 days
153,000
6.51
4.16E-05
0.04
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Paraquat
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 917 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Paraquat
16146
4685147
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0045
0.004
0.93
25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
2001
1979
Critical Effect
Lungs, Thorax, or Respiration - other changes, chronic
pneumonitis
Lungs, Thorax, or Respiration - other changes
Prevalence Magnitude , „ ,
10 8 L' L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in dog; FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year 66, 48593, 2001
Supplemental Data
IYKEDH lyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome,
Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year 10,520,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
31.5
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Paraquat
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 918 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
6,884,630
# PWSs/Sites/
Samples
519
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
48
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former herbicide (HSDB)
Value
38 days
15,473-1,000,000
-4.22
<1E-09
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
p-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 919 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Chloronitro benzene
4072
100005
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.177
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
ZOOS
Critical Effect
Decreased red blood cell count
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Supplemental Data; Journal; Matsumoto et al., 2006 BMDL10=0.177 mg/kg/day
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1996
Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.41
Y/N
Y/N
W/L
M8/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
p-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 920 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (HSDB)
Value
151-476
2.39
453
22
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
p-Chlorotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 921 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Chlorotoluene
4533
106434
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
Decreased body weight gain.
Brain and Coverings - recordings from specific areas of
CNS, Liver - hepatitis (hepatocellular necrosis), zonal,
Liver - liver function tests impaired
3-model Categorical Prediction
NL?
HRL Ratio(s)
NCHRL/NCODR1 90%: 70
Notes
Reference Dose
Reference Dose
Reference Dose IRIS
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.7
140
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
p-Chlorotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 922 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
15,612
21,378
27
25
0.173
0.117
0.02
0.2
6.4
22.5
0.5
0.5
2
5
6.4
22.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,879
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
0
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
0.02
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.4
Non-cancer: 70
Amount Range
>10M-50M
>500K-1M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
3
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
1.7
90% of
Detects
2.74
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Solvent; chemica intermediate (HSDB)
Value
38 days
340
3.33
0.0044
106
20
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
p-Cresidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 923 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Cresidine
5344
120718
Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.15
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1987
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.23
Y/N
Y/N
W/L
W/L
CACART; OEHHA; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
p-Cresidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 924 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; dye intermediate (HSDB)
Value
38 days
53
1.74
1.20E-07
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
p-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 925 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Dinitrobenzene
4094
100254
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
ncreased spleen weight
Prevalence Magnitude ,,, „
1 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Codyetal 1981; Basis NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.7
Y/N
Y/N
W/L
W/L
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
p-Dinitrobenzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 926 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
28,100
28,71 1
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
1
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; dye constituent (HSDB)
Value
221
1.46
3.69E-07
69
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Pentabromodiphenyl ethers
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 927 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentabromodiphenyl ethers
31963
32534819
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
0.007
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
2004
Critical Effect
Induction of hepatic enzymes
nduction of hepatic enzymes
Hepatic
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Carlson, 1980; Basis NOAEL 1.77 mgflsg-d, rat, UF=1000
Reference Dose
Reference Dose; Carlson, 1980; Basis NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level; Int.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pentabromodiphenyl ethers
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 928 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame retardant (HSDB)
Value
30,500
7.66
3.55E-06
0.000079
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant
-------
Pentachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 929 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentachloroethane
2699
76017
Attribute Scores
Potency Severity
4 3
Prevalence Magnitude
4 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
126
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
increased glucose excretion
3-model Categorical Prediction
NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Lowest Observed Adverse Effect Level
Supplemental Data, NTP, NIH Pub 96-3935, 1996
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1999
Vol. 41, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
294
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 ~B cancer risk was used.
-------
Pentachloroethane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 930 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
5
865
# PWSs/Sites/
Samples
429
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
1
4
% PWSs/Sites/
Sam pies with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1M-10M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.asox
ndustrial solvent; chemical intermediate (HSDB)
Value
180 days
1 1 7-244
500
13
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reclacitrant (PBT)
-------
Pentaerythritol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 931 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentaerythritol
5114
115775
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
2,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Diarrhea
Prevalence Magnitude ,,, „
8 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pentaerythritol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 932 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for resins, paints, Pharmaceuticals, insecticides (HSDB)
Value
9
-1.69
4.10E-10
72,300
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
Pentaerythritol dibromide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 933 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentaerythritol dibromide
14700
3296900
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1980
Critical Effect
Sense Organs and Special Senses (Eye) - effect, not
otherwise specified
Prevalence Magnitude ,,, „
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JCTODH Journal of Combustion Toxicology. (Westport,
CT) V.3-9, 1976-82. Volume(issue);page/year 7,77,1980
Supplemental Data;
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
No quantitative data for the cancer endpoint were identified; Cancer classifications were used for
screening, but no related quantitative cancer risk data were identified for potency scoring."
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
233
Y/N
Y/N
M8/L
W/L
IARC; CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pentaerythritol dibromide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 934 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame retardant; polymer intermediate (HSDB)
Value
420
2.29
4.10E-09
38,000
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (BIODEG)
-------
Pentanal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 935 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentanal
4865
110623
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
No effect reported other than lethality.
Prevalence Magnitude
4 8 Li
HRL Ratio(s)
NC HRL/NAWQA 90%: 26.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Sax, N.I. Dangerous Properties of Industrial Materials. 6th ed. New York, NY: Van Nostrand
Reinhold, 1984., p. 2716
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
224
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pentanal
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 936 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF ICR
# PWSs/Sites
sampled
236
#with Detects
1
% PWSs/Sites
with detects
0.42
Mean value of
Detects
8.5
Maximum
value of
Detects
8.5
Median value of
Detects
8.5
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Mean value of
Detects
Non-cancer: 26.4
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; rubber additive (HSDB)
Value
8.7
1,040
1.31
0.000147
13.5
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BF = Biodegrades fast with acclimation
-------
Phenolphthalein
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 937 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenolphthalein
2743
77098
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
400
400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Liver - tumors, Tumorigenic - active as anti-cancer agent
Hyperplasi of the parathyroid, fibrous osteodystrophy
of the bone, hypersplais of the thyroid advanced
nephropathy - clear evidence of cancer in mice and
male rats-some evidence in female rats.
Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/paqe/year
Supplemental Data; NTP report TR-465.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
2000
Vol. 76; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
933
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phenolphthalein
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 938 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1994
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical reagent; medical indicator (HSDB)
Value
38 days
490
2.41
9.00E-16
400
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Phenyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 939 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenyl ether
4208
101848
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
2,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - food intake (animal), Behavioral - muscle
weakness, Gastrointestinal - other changes
Prevalence Magnitude ,,, „
7 5 NL'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear OTS0518143
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phenyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 940 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Synthetic intermediate; in PPCPs (Merck Index, 1983)
Value
1,950
4.21
0.00028
18
ir
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Phenylmercury acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 941 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenylmercury acetate
2433
62384
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00008
0.00008
0.625
13.3
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
2001
1980
Critical Effect
Kidney damage at the LOAEL, kidney lesions at higher
doses
Kidney, Ureter, Bladder - other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Fitzhugh et al., 1950; Basis NOAEL 0.0084 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Fitzhugh etal., 1950; Basis NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1380,2001
Supplemental Data
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho,
Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year 22,291,1980
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.56
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phenylmercury acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 942 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; disinfectant; drug preservative (HSDB)
Value
171.8
0.71
5.65E-10
4,370
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Phenytoin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 943 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenytoin
2317
57410
Attribute Scores 3-model Categorical Prediction
Potency Severity
5
Prevalence Magnitude
1 5
Incomplete data for scoring HRL Ratio(s)
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
Supplemental ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20.5
5
4.3
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
NC HRL/Vanderford MAX: 68.8
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-404,1993
Maximum Recommended Daily Dose (MRDD)
Minimum Therapeutic Dose (MTD)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification
59.1
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
mg/kg-d
1996
Tumorigenic Dose - 50
Vol. 66; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potencv scorinq.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
11.7
Y/N
Y/N
M8/L
W/L
Developmental
CACART
CACART; UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phenytoin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 944 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, 2008
Snyder, 2008
Vanderfordetal., 2006
HRL Ratios (HRL/Vanderford MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
15,981
# PWSs/Sites/
Samples
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites/
Samples with
detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 68.8
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.032
0.04
0.17
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Finished Drinking Water Monitoring; Snyder, Shane A. 2008. Ozone:
Science and Engineering. 30(1): 65-69.
Raw Drinking Water Monitoring; Snyder, Shane A. 2008. Ozone:
Science and Engineering. 30(1): 65-69.
Ambient Water Monitoring; Vanderford etal., 2006 Env. Sci. &Technol.
40(23), pp. 7312-7320.
Pharmaceutical (ChemlDPIus)
Value
38 days
2.47
1.02E-11
32
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slowly with acclimation
-------
Phosmet
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 945 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phosmet
9544
732116
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.011
0.02
0.02
0.01
26
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1998
1969
Critical Effect
RBC & serum ChE inhibition
Red. Body weight; liver cell vacuolization; ChE inhibition
Reduced bodywt; liver cell vacuolization; Cholinerase
inhibition
Behavioral - somnolence (general depressed activity),
Behavioral - muscle contraction or spasticity, Lungs,
Thorax, or Respiration - dyspnea
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NC HRL/GWC EEC: 193
Notes
Reference Dose
Reference Dose; Stauffer Chemical 1967; Basis NOEL 2 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Stauffer Chemical 1967; Basis NOEL/LEL, rat, UF=101
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71.
Discontinued. Volume(issue)/page/year 34(1-3), 192, 1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
77
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phosmet
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 946 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS
# Sam pies
Amount
Released
1,333,468
# PWSs/Sites/
Samples
134
381
11
OPP Estimated Environmental Concentration
HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
% Samples with
detects
Number of
States
40
% PWSs/Sites/
Sam pies with
detects
0
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic:
Non-cancer: 193
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
Not Detected
99% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient and finished
water; method 9002 (GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.4 ug/L
Cancer:
nsecticide (HSDB)
Value
38 days
42.9
2.78
8.39E-09
24.4
19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Phosphorus
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 947 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phosphorus
19191
7723140
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00002
0.00002
0.00002
0.0002
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1997
1989
Critical Effect
Parturition mortality; forelimb hair loss
Behavioral - alteration of classical conditioning
Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/NIRS 90%: 0.00037
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.015 mg/kg-d, UF = 1000, rat, oral (Condray, 1985)
Reference Dose
Reference Dose; Basis = NOAEL/LOAEL, MF = 1 , UF = 1 000, rat (Condray, 1 985)
Minimal Risk Level; Int., oral, UF = 100, Endpoint = repro.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.0005
0.14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Phosphorus
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 948 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
392
39.6
42
555
104
381
1,576
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
8,090
# Sam pies
Amount
Released
4,457
31,102
# PWSs/Sites
sampled
5,432
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
67.1
% Samples with
detects
Number of
States
4
16
% PWSs/Sites
with detects
1
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.00037
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Former pesticide; chemical intermediate; as ammunit
Value
14.3
-0.27
3.5
0.0244
205,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
11,000
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
44
Median value of
Detects
270
90% of
Detects
1,909
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
on (HSDB)
Notes
-------
Phthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 949 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phthalic acid
3343
88993
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
105
0.56
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
Decreased body weight gain
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol)
Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal - Toxicology Letters 93 (1997) 109-115. Ema, et al.
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(8), 12,1 967
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
733
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Phthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 950 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1994
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide (HSDB)
Value
2.5-5 weeks
2-31
0.73
2.00E-11
6,965
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (HSDB)
-------
Piperidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 951 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Piperidine
4890
110894
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
22.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1975
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
5 5 Li~L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New
ndustrial Chemical Substances. For English translation, see TNICS. (Izdatel'stvo Meditsina,
Moscow, USSR) No.1- 1961- Volume(issue);page/year 14,90,1975
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
M8/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Piperidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 952 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; rubber accelerator (HSDB)
Value
0.84
4.35E-06
1,000,000
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
p-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 953 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Nitrosodiphenylamine
6319
156105
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.022
B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-'
(mg/kg-d)"1
1987
Cited by OEHHA
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1.59
Y/N
Y/N
W/L
W/L
CACART; OEHHA; EPA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.
-------
p-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 954 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; food additve; rubber accelerator (HSDB)
Value
38 days
3.16
1.10E-08
17.3
16
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
p-Nitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 955 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Nitrotoluene
4071
99990
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
55
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
splenic lesions
Blood - leukemia, Tumorigenic - active as anti-cancer
agent
Prevalence Magnitude
65 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NTP 1992; Bass LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 105-week oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year NIHNo.01-4432
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.017
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1996
Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2.06
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
p-Nitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 956 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
K0c« Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for dyes (HSDB)
Value
309
2.37
5.63E-06
442
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Poly(dimethyl diallyl ammonium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 957 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Polyfdimethyl diallyl ammonium chloride)
29130
26062793
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
290
1,720
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1988
Critical Effect
Liver - other, blood - changes in spleen
Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Lungs, Thorax, or Respiration - respiratory depression
Prevalence Magnitude ,,, _
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 53(3),66,1 988
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 53(3), 66,1988
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
678
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Poly(dimethyl diallyl ammonium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 958 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
PPCPs (NLM/NIH)
Value
1 5 days
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Potassium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 959 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Potassium
18836
7440097
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
67
0.94
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
No effect
Cardiac - changes in heart weight, Gastrointestinal - other
changes, Blood - changes in cell count (unspecified)
Prevalence Magnitude ,,, „
10 10 NL'
HRL Ratio(s)
NCHRL/NIRS90%: 0.08
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; DRI pg.235; NAS
Lowest Observed Adverse Effect Level; 180-day oral study in rat; VCVN1 "Vrednie chemichescie
veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic
substances containing I-IV group elements), Filov V.A., Chimia, 1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
469
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Potassium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 960 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
958
96.9
311
23,955
1,860
5,939
15,422
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
10,193
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
9,307
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
91.3
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
60
Non-cancer: 0.08
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
3,900,000
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
2,790
90% of
Detects
5,000
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Laboratory reagent (HSDB)
Value
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
p-Phenetidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 961 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Phenetidine
6322
156434
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
0.242
530
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1978
1981
Critical Effect
Bone marrow toxicity, methemaglobinemia, spleen toxicity
Blood - normocytic anemia, Blood -
methemoglobinemia-carboxyhemoglobin, Blood -
other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
58 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/pagefyear 43(1 ),92, 1978; LOAEL was used forpotency scoring because it was
lower than the NO(A)EL from other studies.
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information,
see MTPEEI Vo ume(issue)/page/year 25(8), 50,1981
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.56
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
p-Phenetidine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 962 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate (Merck Index, 1983; OECD SIDS)
Value
1.24
1.50E-07
7,510
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrqades sometimes/recalcitrant (BIODEO)
-------
Prometon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 963 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Prometon
11873
1610180
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.015
0.015
15
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1886
1986
2001
Critical Effect
No treatment related effects observed. Decreased
Potency Score by one integer
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 1 ,438
Notes
Reference Dose
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15 mg/kg-d, rat, UF=1000. IRIS also reports
maternal toxicity in a study not used for the RfD derivation; Severity scored on this critical effect.
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15, rat, UF=1000
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15, rat, UF=1000
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; HBPTO Handbook of pesticide toxicology.
Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1512,2001
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.5
105
Y/N
Y/N
W/L
W/L
1988
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Prometon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 964 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
POP
PPMP
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1/2, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,128
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
609
288
553
1,627
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
26
145
22.8
% Samples with
detects
2.92
0.49
Number of
States
% PWSs/Sites/
Sam pies with
detects
0
4.7
63.6
0.0004
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
0.0025
Non-cancer: 1,438
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
40
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Not Detected
0.0025
0.103
0.014
Median value of
Detects
0.15
0.16
0.073
90% of Detects
0.381
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001 (GC/MS)
Herbicide (HSDB)
Value
60 days
156
2.99
3.18E-09
750
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Propanenitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 965 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propanenitrile
4591
107120
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20
35.8
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1996
Critical Effect
Maternal toxicity and slight fetotoxicity
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal -Johansen etal, 1986
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J., Dangerous Properties of Industrial Materials, 9th Ed., Vol. 1-3, NY, NY, Van Nostrand
Reingold, 1996., p 2799
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Propanenitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 966 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; industrial solvent (HSDB)
Value
1 5 days
29
0.16
3.70E-05
130,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Propargite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 967 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propargite
13082
2312358
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
0.02
0.02
0.01
1,480
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1999
1969
Critical Effect
Decreased body weight & body weight gain, increased
mortality. Q1* 0.0033 (mg/kg-day)-1 . See CAR
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
64 L'
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 477
Notes
Reference Dose
Reference Dose; Uniroyal Chemical, 1966, 1982; Basis NOEL 22.5 mg/kg-d, dog, UF=1000
Reference Dose
Reference Dose; Uniroyal Chemical, 1966; Basis NOEL, dog, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 14,515,1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0033
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
OPP
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
280
Y/N
Y/N
W/L
W/L
Developmental
CACART
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Propargite
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 968 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,108
# Sam pies
Amount
Released
2,538,969
0
253
# PWSs/Sites/
Samples
288
688
62
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0.872
% Samples with
detects
Number of
States
30
0
1
% PWSs/Sites/
Samples with
detects
0
0.0026
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer: 477
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
20
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
0.044
Median value of
Detects
0.587
90% of
Detects
3.5
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Cancer:
nsecticide (HSDB)
Value
60 days
138,000
5
4.16E-08
0.5
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Propargyl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 969 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propargyl alcoho
4597
107197
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002
20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
1982
Critical Effect
Increased liver & kidney weights, megalocytosis of the
iver
iver, kidney
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
66 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S.EPA, 1987; Basis NOAEL 5 mg/kg-d, rat, UF=3000
Reference Dose
Reference Dose; U.S.EPA, 1987; Basis NOAEL/LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds.,
New York, John Wiley & Sons, Inc., 1978-82. Vo . 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
Volume(issue)/page/vear 2C, 4672, 1982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
14
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Propargyl alcohol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 970 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
64,096
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
6
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Corrosion inhibitors; in pharmaceutcals; chemical intermediate (HSDB)
Value
1.325
-0.38
1.15E-06
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF/BST
Notes
BF = Biodegrades fast; BST = Biodegrades sometimes/reca citrant (BIODEG)
-------
Propionaldehyde
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 971 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propionaldehyde
5508
123386
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1971
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 8 L
HRL Ratio(s)
NC HRL/DBP ICR MED: 8.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year
21MAY19T1
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
56
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Propionaldehyde
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 972 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBF ICR
# PWSs/Sites
sampled
236
#with Detects
4
% PWSs/Sites
with detects
1.69
Mean value of
Detects
7.2
Maximum
value of
Detects
9.9
Median value of
Detects
6.8
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
9,607
699,803
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
4
15
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 8.2
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; chemical intermediate (HSDB)
Value
15 days
50
0.59
7.30E-05
306,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slowly
-------
Propionic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 973 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propionic acid
2861
79094
Attribute Scores
Potency Severity
3 6
Prevalence Magnitude
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
735
1,640
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
hyperplasia of the esophagus; nitrite in urine
Details of toxic effects not reported other than lethal dose
value
3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPP RED
Lowest Observed Adverse Effect Level
Supplemental Data
Rat; GISAAA G giena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 39(4), 86,1974
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5,145
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Propionic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 974 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Pesticide; food additive; chemica intermediate (HSDB)
Value
up to 21 days
36
0.33
1,000,000
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (HSDB)
-------
Propoxyphene hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 975 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propoxyphene hydrochloride
11929
1639607
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
207
82
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1971
1971
Critical Effect
Liver - changes in liver weight, Blood - changes in
erythrocyte (RBC) count, Nutritiona and Gross
Metabolic - weight loss or decreased weight gain
Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - respiratory depression
Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TXAPA9 Toxicology and Applied Pharmacology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year
19,452,1971
Supplemental Data
Rabbit; TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN
55802) V.1- 1959- Volume(issue)/page/year 19,445,1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
483
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Propoxyphene hydrochloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 976 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1990
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
d-isomer as veterinary medicine (HSDB - CASRN 469-62-5)
Value
38 days
4.18
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
Kow for d-propoxyphene
-------
Propylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 977 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glycol
2323
57556
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
hematological changes
Blood - normocytic anemia, Blood - other hemolysis with or
without anemia
Prevalence Magnitude
10 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Bauer et al; Basis LOAEL, cat, UF = 3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in dog; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
3,500
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Propylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 978 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food additive; in PPCPs; as coolant (HSDB)
Value
1
-0.92
1.31E-10
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Propylene glycol 1-methyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 979 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glycol 1 -methyl ether
4655
107982
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.7
5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1972
Critical Effect
Histo pathology
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
88 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1 991 ; Basis NOEL = 1 mg/kg-d, rat, UF = 1 000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Dog; ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(ssue)/page/year 22,569,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
4,900
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Propylene glycol 1-methyl ether
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 980 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n paints and coatings; pesticide so vent (HSDB)
Value
1 5 days
1
-0.49
9.20E-07
1,000,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Propylene glycol monomethyl eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 981 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glyco monomethyl ether acetate
4706
108656
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
300
8,532
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased body weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
DOWCC Dow Chemical Company Reports. (Dow Chemical USA, Health and Environment Research,
Toxicology Research Lab., Midland, Ml 48640) Vo ume(issue)/page/year MSD-1582
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,100
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Propylene glycol monomethyl eth
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 982 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units
Cancer:
Notes
Pesticide inert (EPA OPP)
Value
15
0.56
3.44E-06
198,000
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Propylene glycol mono-t-butyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 983 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glyco mono-t-butyl ether
37358
57018527
Attribute Scores
Potency Severity
Prevalence Magnitude
5 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Equivocal evidence of carcinogenicity
n male rats; clear evidence in male/female mice (NTP)
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Propylene glycol mono-t-butyl
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 984 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; in PPCPs; in paints and coatings (HSDB)
Value
5
0.87
4.73E-06
173,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST= biodegrades sometimes / reca citrant (HSDB)
-------
Pyrazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 985 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyrazon
12037
1698608
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.18
66
493
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1992
1992
Critical Effect
Decreased body weight & body weight gain
Liver - changes in liver weight, Endocrine - changes in
thyroid weight, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,3171,1992
Supplemental Data
Guinea pig; NNGADV Nippon Noyaku Gakkaish . Journal of the Pesticide Science Society of Japan.
(Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
Volume(issue)/page/year 1 7,S1 71 ,1 992
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,260
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Pyrazon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 986 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
118,294
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
9
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (HSDB)
Value
38 days
33-346
1.14
6.50E-12
400
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrdaes slow with acclimation (PBT)
-------
Pyridine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 987 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyridine
4887
110861
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.001
0.255
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1958
Critical Effect
ncreased liver weight
Blood - change in clotting factors, Related to Chronic Data -
death
Prevalence Magnitude
99 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S.EPA, 1986; Basis NOAEL = 1 mg*g-d, rat, UF = 1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 14-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 23(7), 30,1 958
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pyridine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 988 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
526
1,302,842
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
6
21
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent; chemica intermediate; food additive; unreg stered pesticide (HSDB)
Value
33
0.65
1.10E-05
1,000,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA/BST
Notes
BFA = Biodegrades fast with acclimat on/BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
Pyridine, pentachloro-
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 989 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyridine, pentachloro-
12850
2176627
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
435
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral -somno ence (general depressed activity),
Behavioral -convulsions or effect on seizure threshold
Prevalence Magnitude
67 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0536503, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Pyridine, pentachloro-
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 990 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemica
Value
1 80 days
2,000
3.53
6.30E-03
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
Quartz (SiO2)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 991 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quartz (Si02)
24322
14808607
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
120,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - other changes
Prevalence Magnitude
1
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect LevelEPASR United States Environmental Protection Agency,
Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
Washington, DC 20460) History unknown. Vo ume(issue)/page/year#86940001000,1994. Rodent -
rat.
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
1
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
280,000
Y/N
Y/N
W/L
W/L
IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Quartz (SiO2)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 992 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10K-50K
>10K-50K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Naturally-occurring mineral
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
Quizalofop
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 993 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quizalofop
76725
76578126
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Prevalence Magnitude
10 8
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Quizalofop
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 994 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
340,818
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
35
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Derivative of the herbicide quizalofop-ethyl (HSDB)
Value
38 days
3.57
0.3
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Santoflex 13
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 995 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Santoflex 13
9730
793248
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6
62.3
3,580
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Liver cell enlargement or alteration
Liver - changes in liver weight, Blood - normocytic anemia,
Blood - changes in leukocyte (WBC) count
Sense Organs and Special Senses (Eye) - effect, not
otherwise specified, Behavioral - food intake (animal),
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude ,,, _
7 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0545431
Supplemental Data
rodent-rat; ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary
Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year 1,67,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
42
Y/N
Y/N
M8/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Santoflex 13
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 996 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Antioxidant/antiozonant (HSDB)
Value
38 days
11
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Sethoxydim
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 997 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sethoxydim
65122
74051802
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.14
0.09
0.09
3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Liver effects: hepatocellular hypertrophy & fatty
degeneration
Mild anemia in males
Mild anemia in males
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose, BASF Corporation, 1984
Reference Dose, BASF Corporal on, 1984, NOEL = 9.41 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose, BASF Corp., 1984, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C274,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
980
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sethoxydim
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 998 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
1,717,271
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
48
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Herbicide (HSDB)
Value
38 days
2,845
4.38
2.16E-11
25
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Silicon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 999 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Silicon
18845
7440213
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3,160
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
10 10
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No. ?-57, 1948-77. Discontinued.
Volume(issueypage/year53A,21,1974, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Silicon
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1000 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
989
100
0.26
98.9
18.1
42.1
67.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
mg/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; alloys (HSDB)
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
Sodium
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1001 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium
18847
7440235
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
9.38
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Cardiac - changes in heart weight, Gastrointestinal -
other changes, Blood - changes in cell count
unspecified)
Prevalence Magnitude , „
10 10 L
HRL Ratio(s)
NCHRL/NIRS90%:0.14
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, VCVN1 "Vrednie chemichescie veshestva.
Neorganicheskie soedinenia e ementov I-IV groopp" (Hazardous substances. Inornanic
substances containing l-IVgroup elements), Filov V.A., Chimia, 1988. Volume(issue)/page/year -
,36,1988
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
CADW
EPA HA
Health Reference Level (HRL)2 cancer
21.9
200
20
Y/N
Y/N
M8/L
mg/L
mg/L
M8/L
F'03
Drinking Water Equivalent Level
Aesthetic Objective (AO)
Health Advisory Status For individuals on a SOOmg.day restiricted sodium diet
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1002 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
989
100
0.907
1,541
16.4
160
498
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
CAL DHS
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,845
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
11,826
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
99.8
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
7
Non-cancer: 0.14
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
173,000,000
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
mg/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
90% of
Detects
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Chemical intermed ate; alloys; sem conductors (HSDB)
Value
14.3
-0.77
0.0246
445,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant
-------
Sodium azide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1003 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium azide
29534
26628228
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.004
0.004
5
0.25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1999
Critical Effect
Clinical signs (e.g., hunched postures) & reduced body
weight
Clinical signs & reduced body weight
Cardiac - EKG changes not diagnostic of specified effects,
Liver - liver function tests impaired, Kidney, Ureter,
Bladder - other changes in urine composition
Prevalence Magnitude
3 6 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; NCI, 1981; Basis NOEL = 5 mg/kg-d, rat, UF = 1,000
Reference Dose
Reference Dose; NCI, 1981; Bas s NOAEL/LOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in unspecified mammal; STGNBT
"Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh
Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia,
zd AT 1 999 Volume(issue)/page/year -, 1 73, 1 999
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
28
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium azide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1004 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
66,425
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
3
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; herbicide (HSDB)
Value
1.342
0.16
7.78E-05
36,700
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Sodium benzoate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1005 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium benzoate
7550
532321
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,505
2,090
1,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
1993
1986
Critical Effect
Behavioral - convulsions or effect on seizure threshold,
Nutritional and Gross Metabolic - weight loss or decreased
weight gain, Related to Chronic Data - death
Increased liver and kidney weight, increased serum
albumin and total protein, increased GGT, enlarged
hepatocytes with glassy cytoplasm
Behavioral - changes in motor activity (specific assay),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude ,,, „
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; TRENAF Kenkyu Nenpo-Tokyo-toritsu
Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-
toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50-
Volume(issue)/page/year42,285,1991
Supplemental Data, Fujitani, 1993
rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 51(1), 75,1986
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
14,630
Y/N
Y/N
M8/L
W/L
Teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium benzoate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1006 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food and pharmaceutical preservative; medication (HSDB)
Value
1 5 days
556,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Sodium bromide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1007 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium bromide
19109
7647156
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.129
3,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1972
1935
Critical Effect
Liver -changes in liver weight, Biochemical -Enzyme
inhibition, induction, or change in blood or tissue
evels - transaminases
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 37(1), 13,1972, rodent-rabbit
Supplemental Data
rat study; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co.,
428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 55,200,1935
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.3
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium bromide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1008 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1990
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Photographic chemical; in chemica synthesis (HSDB)
Value
909,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Sodium chlorate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1009 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium chlorate
19266
7775099
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
1.36
1,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
2001
Critical Effect
Thyroid hypertrophy
Blood - pigmented or nucleated red blood cells, Blood -
changes in erythrocyte (RBC) count, Nutritional and Gross
Metabolic - weight loss or decreased weight gain
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
9 8 L
HRL Ratio(s)
NC HRL/SWC EEC: 304
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in rat; JEPOEC Journal of Environmental
Pathology, Toxicology and Oncology. (Chem-Orbtal, POB134, Park Forest, IL 60466) V.5(4)- 1984-
Volume(issue)/page/year 6(1), 105,1 985
Supplemental Data
rodent-rat; HBPTO Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year2,1412,2001
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
210
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium chlorate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1010 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
7,261 ,557
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
16
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
Surface water chronic: 0.69 ug/L
Non-cancer: 304
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic:
Cancer:
Herbicide; oxidizing agent in PPCPs and industrial processes (HSDB)
Value
75,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Sodium chloroacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1011 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium chloroacetate
15383
3926623
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
60
95
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
1941
Critical Effect
Liver - changes in liver weight, Kidney, Ureter, Bladder
changes in bladder weight, Blood - changes in
eukocyte (WBC) count
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; TXCYAC Toxicology. (Elsevier
Scientific Pub. Ireland, Ltd., POB85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year
67,171,1991
Supplemental Data
rodent-rat; JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V. 18-31, 1936-49.
For publisher information, see AEHLAU. Volume(ssue)/page/year 23,78,1941
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Sodium chloroacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1012 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemica
Value
1 5 days
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Sodium dimethyldithiocarbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1013 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium dimethyldithiocarbamate
5680
128041
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
114
300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1976
2000
Critical Effect
Developmental toxicity
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
77 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplimental Data, Toxicology and Applied Pharmacology VolumeSS, Issue 1, January 1976,
Pages 83-94
rodent- rabbit; TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia)
History Unknown Volume(issue)/page/year (3), 34,2000
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
266
Y/N
Y/N
W/L
W/L
developmental
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Sodium dimethyldithiocarbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1014 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
31,009
129,318
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
3
9
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial antimicrobial (HSDB)
Value
0.01 3-1. 08 days
2.2
1,000,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Sodium dodecylbenzenesulfonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1015 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium dodecylbenzenesulfonate
28421
25155300
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
101
438
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1975
1972
Critical Effect
Liver - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cho esterol), Nutritiona
and Gross Metabolic - changes in iron
Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral - somno ence (general depressed activity),
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AECTCV Archives of Environmental Contamination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issueypage/year 3,1 15,1 975
Supplemental Data
rodent- rat; TRENAF Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo
Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1 , 3-chome,
Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- Volume(issue)/page/year 24,397,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
236
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium dodecylbenzenesulfonate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1016 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Detergent; in pesticide formulations (HSDB)
Value
1 5 days
111
0.45
6.27E-08
800,000
21
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Sodium fluoroacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1017 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium fluoroacetate
2445
62748
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00002
0.00002
0.00002
0.0216
0.066
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1960
1951
Critical Effect
Histopathology & decreased size & weight of testes
and epididymides
ncr. heart weight; reproductive effects in male
increased heart wt, decreased testiswt, altered
spermatogenesis
Related to Chronic Data - death
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1988, Basis NOAEL = 0.05 mg/kg-d, rat, UF = 3,000
Reference Dose
Reference Dose; USEPA, 1988, oral study in rats, UF = 3,000, Basis NOAEL/LOAEL
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in domestic mammal; JCPTA9 Journal of
Comparative Pathology and Therapeutics. (Liverpool, UK) V.1-74, 1883-1964. For publisher information,
see JCVPAR. Volume(issue)/page/year 70,145,1960
Supplemental Data
mammal- dog; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins
Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 101,82,1951
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.14
Y/N
Y/N
W/L
W/L
Male reproductive
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium fluoroacetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1018 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
0
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
0
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2002
2002
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Rodenticide (HSDB)
Value
1.201
-3.78
1.09E-06
111,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (HSDB)
-------
Sodium hypochlorite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1019 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium hypochlorite
19138
7681529
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
Scores based on parent
HEALTH EFFECTS DATA1 See parent Sodium
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
9.38
5,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1986
Critical Effect
Cardiac - changes in heart weight, Gastrointestinal -
other changes, Blood - changes in cell count
(unspecified)
(for parent sodium)
Behavioral - changes in motor activity (specific assay),
Gastrointestinal - other changes
Prevalence Magnitude , „
10 10 L
Scores based on parent HRL Ratio(s)
NC HRL/NIRS 90%: 0.14 (HRL and NIRS based on
parent Sodium)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, VCVN1 "Vrednie chemichescie veshestva.
Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic
substances containing I-IV group elements), FilovV.A., Chimia, 1988. Volume(issueypage/year-
,36,1 988; 9 week study in rats.
Supplemental Data
rodent- mouse; SKEZAP Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. (Nippon Shokuhin Eisei
Gakkai c/o Shokuhin Eisei Senta, 2-6-1 Jingumae, Shibuya-ku, Tokyo 150, Japan) V.1- 1960-
Volume(issue)/page/year27,553,1986
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
21.9
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on parent Sodium
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium hypochlorite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1020 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
989
100
0.907
1,541
16.4
160
498
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 0.14
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
mg/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
For parent sodium
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Bleach; disinfectant; medication (HSDB)
Value
293,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Sodium methyldithiocarbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1021 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium methyldithiocarbamate
5951
137428
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
20.2
50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
1965
Critical Effect
Blood - normocytic anemia, Blood - pigmented or
nucleated red blood cells, Blood - leukopenia
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „ ,
9 10 L"L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issueXpage/year 32(2),1 1 ,1967; 30 week rabbit study
Supplemental Data
rodent- mouse; RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz
Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year 10,97,1965
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
47.1
Y/N
Y/N
W/L
W/L
Developmental
CACART
CACART
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium methyldithiocarbamate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1022 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
60,023,092
40
10,500
OPP Estimated Environmental Concentration
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
20
1
2
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Surface water chronic: 0 ug/L
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic: 0 ug/L
Cancer:
Soil fumigant (HSDB)
Value
-2.62
722,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (HSDB)
-------
Sodium sulfide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1023 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium sulfide
11113
1313822
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
205
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 10
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1 -36, 1957-1992. For publisher
information, see MTPEEI Volume(issue);page/year 30(8),30,1 986, rodent-mouse
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Sodium sulfide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1024 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Metal precipitation; chemical reagent; medication (HSDB)
Value
186,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (HSDB)
-------
Sodium vanadate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1025 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium vanadate
23292
13718268
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.616
74.6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1984
Critical Effect
Kidney- Impaired function
Gastrointestinal - ma absorption, Kidney, Ureter, Bladder -
changes in bladder weight, Nutritional and Gross
Metabolic - changes n calcium
Behavioral - ataxia, Lungs, Thorax, or Respiration -
dyspnea, Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1987, NOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 37,899,1986
Supplemental Data
rodent- mouse; TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(ssue)/page/year 23,227,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sodium vanadate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1026 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial chemica
Value
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Sorbitol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1027 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sorbitol
2145
50704
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
833
1,167
15,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999
1974
Critical Effect
Gastrointestinal - other changes
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
7 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, FGTOD7 Food and Chemical Toxicology. (Pergamon
Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year 37,233,1999, mammal- human study
Supplemental Data
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued.
Volume(issue)/page/year 53A, 498,1 974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2,723
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Sorbitol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1028 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Food and pharmaceutical additive (HSDB)
Value
2
-2.2
7.30E-13
2,200,000
27
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (HSDB)
-------
Spinosyn A
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1029 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Spinosyn A
70751
131929607
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
9 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
Critical Effect
Vacuolation of the thyroid gland epithelial cells,
inflammation in the thyroid, lung, and larynx; bone-
marrow hyperplasia and dilatation of liver sinusoids
3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/SWC EEC: 1,522
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Acute RfD unnecessary
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Spinosyn A
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1030 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
# Sam pies
Amount
Released
117,315
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
21
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
Surface water chronic: 0.092 ug/L
Non-cancer: 1,522
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Notes
Ground water chronic
Cancer:
nsecticide (HSDB)
Value
2.8
89.4
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Stearic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1031 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Stearic acid
2305
57114
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1,490
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
Critical Effect
Related to Chronic Data - death
Prevalence Magnitude .,, „
8 3 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, JACTDZ Journal of the American College of Toxicology.
(Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-15, 1982-1996. Discontinued.
Volume(issue)/page/year 14,196,1995, 30 week rodent-rat study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3,478
Y/N
Y/N
M8/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Stearic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1032 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>500M-1B
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; food and pharmaceutical additive (HSDB)
Value
720,000
8.23
4.80E-07
0.568
4
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Sulfurous acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1033 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulfurous acid
19341
7782992
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1906
Critical Effect
Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - nausea or vomiting, Gastrointestinal •
other changes
Prevalence Magnitude
5
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AEXPBL Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see
NSAPCC. Volume(issue)/page/year 54,421,1906, human study
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.17
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Sulfurous acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1034 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1994
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Reaction product of SO2 and H2O
Value
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Sulfuryl fluoride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1035 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulfuryl fluoride
13814
2699798
Attribute Scores
Potency Severity
6 6
Prevalence Magnitude
2 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
Critical Effect
Vacuolization of the white matter in the brain in female
rabbits
3-model Categorical Prediction
NL7-L?
HRL Ratio(s)
No water data
Notes
Reference Dose, 1/006
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Zenz, C. Occupational Medicine- Principles and Practical Applications. 2nd ed. St. Louis, MO: Mosby-
Yearbook, Inc, 1988., p. 684, rat and guinea pig study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
21
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sulfuryl fluoride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1036 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
142,720
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
2
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
nsecticide/fumigant; chemical intermediate (HSDB)
Value
750
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Sulprofos
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1037 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulprofos
32748
35400432
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.6
65
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1977
Critical Effect
Blood - normocytic anemia, Blood - changes in serum
composition (e.g. TP, bilirubin, cho esterol),
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - true cholinesterase
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
7 6 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Otawerved Adverse Effect Level, NNQADV Nippon Noyaku Gakkaishi. Journal of the
Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku,
Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year 12,775,1987, 13 week rodent- rat study
Supplemental Data
rodent- rat; 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson
Publications, 1976/77 revision Volume(issue)/page/year 1,205,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1.4
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Sulprofos
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1038 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
308,039
# PWSs/Sites/
Samples
283
669
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
8
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 9002(GC/MS)
Cancer:
Cancelled insecticide (HSDB)
Value
38
12,000-13,500
5.48
8.60E-07
0.31
7
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Tartrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1039 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tartrazine
12444
1934210
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
773
7.5
12,750
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2006
1966
Critical Effect
Neurobehavioral effects
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
5 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, Tanaka Food chem Toxicol 44:179-87 2006
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
rodent- mouse; FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77.
Discontinued. Volume(issue)/page/year 386,88,1966
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
1,804
Y/N
Y/N
W/L
W/L
teratogen list
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tartrazine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1040 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
n sanitizing solut
Value
300,000
50
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ons (food industry); in dyes (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (HSDB)
-------
Tebuthiuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1041 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tebuthiuron
32336
34014181
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.07
0.07
0.07
0.07
7
96
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1992
Critical Effect
Reduced body weight gain in F1 females
Depressed body wieght gain in F1 males
Depressed body weight gain in females
Gastrointestinal - changes in structure or function of
endocrine pancreas, Kidney, Ureter, Bladder - changes in
bladder weight
Prevalence Magnitude .,, .,, „
10 3 NL'NLi
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 7,424
Notes
Reference Dose
Reference Dose, Elanco Products, 1981, Basis NOEL = 7 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, Elanco Products, 1981, NOEL/LEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,335,1992
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
D
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2
490
Y/N
Y/N
mg/L
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tebuthiuron
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1042 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,097
# Sam pies
Amount
Released
115,712
0
5
# PWSs/Sites/
Samples
154
336
# PWSs/Sites/
Samples
66
799
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
19
64
42
#with Detects
11.26
% Samples with
detects
Number of
States
2
0
1
% PWSs/Sites/
Sam pies with
detects
1.9
5.7
28.1
18.7
% PWSs/Sites/
Sam pies with
detects
0
0.001
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
16.3
1
Minimum value of
Detects
Non-cancer: 7,424
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
17.3
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
16.3
14
0.032
0.077
Maximum
value of
Detects
0.013
Median value of
Detects
0.066
90% of
Detects
0.546
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Median value of
Detects
95% of
Detects
0.019
0.077
90% of
Detects
Units for Mag
data
ng/L
ng/L
ug/L
ug/L
Units for Mag
data
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) 9060(HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Cancer:
Herbicide (HSDB)
Value
38
22.8
1.79
1.20E-10
2,500
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Terbufos-O-analogue sulfone
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1043 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Terbufos-O-analogue sulfone
76778
56070156
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
Scores based on parent
Prevalence Magnitude ,,,
1 1 NL
Scores based on parent HRL Ratio(s)
HEALTH EFFECTS DATA1 See Terbufos and Terbufos sulfone Parent Terbufos and Terbufos sulfone on CCL for parent terbufos)
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Plasma ChE inhibition
Notes
Reference Dose - FOR PARENT TERBUFOS
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.35
Y/N
Y/N
ug/L
M/L
Drinking Water Equivalent Level
Based on data for parent terbufos
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.
-------
Terbufos-O-analogue sulfone
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1044 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Finished Water Occurrence Data FOR TERBUFOS - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300
0
0
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of
Detects
99% of Detects
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
Ambient Water Occurrence Data FOR TERBUFOS - PARENT
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP finished water
PPMP ambient water
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,72, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Samples
Amount
Released
# PWSs/Sites/
Samples
22
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
0
0.31
% Sam pies with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
0.9
0
0.0021
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 1.67
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
0.56
Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
0.016
0.017
Median value of
Detects
0.21
90% of
Detects
0.56
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Notes
Pesticide Pilot Mentoring Program (USGS/EPA)
Pesticide Pilot Mentoring Program (USGS/EPA)
Cancer:
NAWQA data and HRL for Parent Terbufos
Analogue and degradate of the pesticide terbufos
Value
38 days
14
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA= Biodegrades slow with acclimaton (PBT)
-------
Terephthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1045 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Terephthalic acid
4091
100210
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1
143
3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1971
Critical Effect
Bladder- Hyperplasia
Brain and Coverings - changes in brain weight, Cardiac -
changes in heart weight, Kidney, Ureter, Bladder -
changes in bladder weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1986, NOEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0543783
Supplemental Data
rodent- mouse; KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650)
Volume(issue)/page/year 21 MAY1 971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7,000
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Terephthalic acid
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1046 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in poultry feeds (HSDB)
Value
71.6
2
3.89E-13
15
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
tert-Butanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1047 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butanol
2670
75650
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
90
107
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
Critical Effect
Decreased body weight males; increased relative and
absolute and relative kidney weights Cancer some
evidence in male rats and female mice, equivocal
evidence in male mice and no evidence in female rat
Liver - other changes, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Prevalence Magnitude , „
10 9 L
HRL Ratio(s)
NCHRL/CALDHS90%:21.1
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP TR436
Lowest Observed Adverse Effect Level; 10-week oral study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
80,97,1995
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
630
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
tert-Butanol
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1048 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
12,324
1,548,617
# PWSs/Sites/
Samples
7,600
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
86
% Samples with
detects
Number of
States
7
31
% PWSs/Sites/
Samples with
detects
1.13
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
2
Non-cancer: 21.1
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
93
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
3.95
90% of
Detects
29.9
Units for Mag
data
ug/L
Cancer:
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Former pesticide; gasoline additive; in PPCPs (HSDB)
Value
37
0.35
9.05E-06
1,000,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS/BST
Notes
BS = Biodegrades slow (BIODEG); BST = Biodegrades sometimes/recalcitrant (BIODEG)
-------
tert-Butyl hydroperoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1049 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butyl hydroperoxide
2693
75912
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
320
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1979
Critical Effect
Behavioral - irritability, Gastrointestinal - alteration in
gastric secretion, Blood - hemorrhage
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New
ndustrial Chemical Substances. For English translation, see TNICS. (Izdatel'stvo Meditsina,
Moscow, USSR) No.1- 1961- Volume(issue)/page/year 15,90,1979, rodent-mouse
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
tert-Butyl hydroperoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1050 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; chemical intermediate (HSDB)
Value
1 5 days
97
0.94
1.60E-05
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
tert-Butylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1051 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butylamine
2669
75649
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
44
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Liver - other changes
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/page/year OTS0534846, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
tert-Butylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1052 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate for rubber accelerators, insect
Value
1 5 days
40
0.4
1,000,000
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Maximum
value of
Detects
Year
1997
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
cides, fungicides, dyestuffs, Pharmaceuticals and oil additives (HSDB)
Notes
BS = Biodegrades s ow (PBT)
-------
tert-Butyl benzene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1053 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butylbenzene
3932
98066
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
4.42
3,045
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1990
Critical Effect
Behavioral -alteration of classical conditioning
Prevalence Magnitude ,,, „
3 6 NL'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 1.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGH "Vredniechemichescie veshestva,
galogenproisvodnie uglevodorodov". (Hazardous substances Galogenated hydrocarbons)
Sandman A. L. etal.,Chimia, 1990. Volume(issue)/page/year -,179, 1990; 24 week oral study in rats
Supplemental Data
rat study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
10.3
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
tert-Butyl benzene
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1054 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
12,353
22,973
24
25
0.19
0.11
0.02
0.10
10
77.5
0.8
0.5
10
5
10
77.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309
# Sam pies
Amount
Released
# PWSs/Sites/
Samples
11,885
10
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
0.232
% Samples with
detects
Number of
States
% PWSs/Sites/
Samples with
detects
0.02
0.009
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.62
Non-cancer: 1.03
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.1
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.9
0.06
Median value of
Detects
0.11
90% of
Detects
1.1
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
0.76
90% of
Detects
0.872
Units for Mag
data
ug/L
Cancer:
Notes
Solvent; in organ c synthesis (HSDB)
Value
38 days
1,181
4.11
0.0132
29.5
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Tetraethyl lead
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1055 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetraethyl lead
2781
78002
Attribute Scores 3-model Categorical Prediction
Potency Severity
10 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0000001
0.06
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
1983
Critical Effect
Histopathology of liver & thym us
Endocrine - other changes
Prevalence Magnitude
5 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose; Basis = LOAEL 0.0012 mg/kg-day, rat, UF = 10,000 (Schepers, 1364)
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 6W-C; JANSY Journal of the autonomic nervous
system (Amsterdam, Elsevier/North Holland Biomedical Press) V.1-81 1979-2000.
Volume(issue)/page/year8,287,1983
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.0007
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tetraethyl lead
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1056 of 1124
OCCURRENCE DATA1
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former anti-knock agent in gasol ne; chemical intermediate (HSDB)
Value
758
4.15
0.568
0.29
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DS
Notes
DS = Degrades slow (HSDB)
-------
Tetrafluoroethene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1057 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrafluoroethene
5138
116143
Attribute Scores
Potency Severity
Prevalence Magnitude
7 7
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1999
Vol. 19, Suppl 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
CACART; IARC; Clear evidence of carcinogenicity in male and female rats and mice (NTP).
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tetrafluoroethene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1058 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Polymer intermec
Value
110
0.63
159
44
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate; in propellants (HSDB); gas
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (HSDB)
-------
Tetrahydrofuran
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1059 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrahydrofuran
4813
109999
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
481
38.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2000
1967
Critical Effect
Systemic parental and developmental toxicity.
Blood - change in clotting factors, Blood - changes in
eukocyte (WBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain
Prevalence Magnitude , „
96 L
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 375
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Oral study
Supplemental Data
No Observed Effect Level
Supplemental Data; (Hellwig, et al. Food and Chemical Toxicology 40 (2002) 1515-1523)
Lowest Observed Adverse Effect Level; oral study in rat 17W-I; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(2), 99,1 967
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
3,366
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tetrahydrofuran
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1060 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,601
# Sam pies
Amount
Released
# PWSs/Sites
sampled
93
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3.58
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
0.07
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 375
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1,430
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.75
Median value of
Detects
8.98
90% of
Detects
1,146
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Solvent (HSDB)
Value
15 days
18-23
0.46
7.10E-05
1,000,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Tetramethylammonium chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1061 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetramethylammonium chloride
2662
75570
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Behavioral -somnoence (general depressed activity),
Behavioral - convulsions or effect on seizure
threshold, Skin and Appendages - hair
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year OTS0536975)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tetramethylammonium chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1062 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Drug / Therapeutic Agent (NLM/NIH/ChemlDPIus)
Value
1 5 days
-4.18
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Tetramethylammonium hydroxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1063 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetramethylammonium hydroxide
2664
75592
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
5
34
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased relative organ weight
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level; NOEL Type - Repeat Dose
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
35
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tetramethylammonium hydroxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1064 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n semiconductor manufacturing (NLM/NIH/Haz-map)
Value
1 5 days
-2.47
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Tetrasodium EDTA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1065 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrasodium EDTA
2459
64028
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
250
2,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1966
2004
Critical Effect
No observed effects
Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Oser et al, 1 966
Lowest Observed Adverse Effect Level
Supplemental Data
European Chemicals Bureau; IUCLID Dataset, Tetrasodium ethyleneadiaminetetraacaetate (64-02-8)
(2000 CD-ROM edition). Available from the database query page: http://ecb.jrc.it/esis/esis.php as of
February 18, 2004.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
1,750
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tetrasodium EDTA
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1066 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chelating agent (HSDB)
Value
60 days
500,000
50
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
Texanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1067 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Texanol
28538
25265774
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
Details of toxic effects not reported otherthan lethal
dose value
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/pagefyear
M-158E.1981)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.
-------
Texanol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1068 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
XIOOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
n latex paints; chemical intermediate (OECD/SIDS)
Value
1 5 days
20
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Thifensulfuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1069 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thifensulfuron
66172
79277671
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Decreased body weight and body weight gain
Prevalence Magnitude , „
10 7 L
Scores based on parent HRL Ratio(s)
No water data
Notes
Reference Dose (for thifensulfuron-m ethyl)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
140
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
Based on RfD for thifensulfuron-methyl.
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thifensulfuron
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1070 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
105,145
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
37
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Data for thifensulfuron-methyl
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Derivative of the pesticide thifensulfuron-methyl (HSDB)
Value
60 days
38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Thiocarbazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1071 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiocarbazide
12972
2231574
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
Critical Effect
Behavioral - somno ence (general depressed activity),
Behavioral - convulsions or effect on seizure
threshold, Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude , „
57 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(MTPEEI Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology.
(Mezhdunarodnaya Kniga, ul.B. Yakimanka, 39 1 17049 Moscow, Russia) No.1- 1993-
Volume(issue)/page/year(2),43,1994)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Thiocarbazide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1072 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E( Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Veterinary medic ne; microscopy reagent (HSDB)
Value
15 days
-2.04
5,500
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Thiophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1073 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiophenol
4734
108985
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00001
0.01
46.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1994
1958
Critical Effect
Centrilobular eosinophilic changes
Behavioral - changes in motor activity (specific assay),
Blood - changes in leukocyte (WBC) count, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases
Behavioral - somnolence (general depressed activity),
Behavioral - coma, Lungs, Thorax, or Respiration -
respiratory depression
Prevalence Magnitude ,,, „
1 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 1,7,1994
Supplemental Data
AIHAAP American Industrial Hyg ene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH
44311) V.19- 1958- Volume(issue)/page/year 19,171,1958
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
0.07
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thiophenol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1074 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for pesticides, Pharmaceuticals and dyes; mosquito larvicide (HSDB)
Value
1 5 days
268
2.52
0.000335
835
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Thiram
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1075 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiram
5945
137268
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.005
0.005
0.01
0.005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
1992
1993
Critical Effect
Changes in hematology, clinical chemistry, incidences
of bile duct hyperplasia, & reduction in mean body
weight gain
Neurotoxicity
Neurotoxicity
Cardiac - arrhythmias (including changes in conduction),
Cardiac - other changes
Prevalence Magnitude
95 Li
HRL Ratio(s)
NC HRL/SWC EEC: 24.4
Notes
Reference Dose
Reference Dose; Basis = NOEL 5 mg/kg-day, rats, oral, UF = 1000 (DuPont, 1954)
Reference Dose
Reference Dose; Basis = NOEL/LEL, rats, oral, lowconf, UF = 100, MF = 1 (DuPont, 1954)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in pig; CUTOEX Current Toxicology. (Nova Science
Publishers, Inc., 6080 Jericho Turnpike, Suite 207, Commack, NY 11725) V.1 1993-
Volume(issue)/page/year 1,221,1993.
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Vol53; 1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
105
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thiram
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1076 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
# Sam pies
Amount
Released
179,809
34
102,508
#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
% Samples with
detects
Number of
States
21
5
21
Minimum value of
Detects
Units
States
States
States
Maximum
value of
Detects
Year
1997
2004
2004
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Supplemental Water Data
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 4.3 ug/L
Non-cancer: 24.4
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Ground water chronic: 0.84 ug/L
Cancer:
Pesticide; rubber accelerator; antiseptic (HSDB)
Value
1 5 days
10
1.73
3.03E-07
835
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slow (PBT)
-------
Thorium-232
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1077 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thorium-232
18853
7440291
Attribute Scores 3-model Categorical Prediction
Potency Severity
Prevalence Magnitude
5 8
No further evaluation for CCL - regulated under Radionuclides Rule. HRL Ratio(s)
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
1.01E-10
mg/L
risk/pCi
(mg/kg-d)-1
(mg/kg-d)"1
pCi = picoCuries
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Thorium-232
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1078 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
989
5
0.506
61.7
6
39
59
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Nuclear reactors; welding; ceramics (HSDB)
Value
150,000
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
Notes
-------
Tralomethrin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1079 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tralomethrin
42610
66841256
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0075
0.0075
10
99
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Decreased body weight gain; increased water
consumption
Behavioral - tremor, Behavioral - ataxia, Gastrointestinal -
nausea or vomiting
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 3 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Basis: NOEL of 0.75 mglkgWay in oral Rat study (Roussel UCLAF, 1 984); UF =
100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in dog 13W-C; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS05451 97
Supplemental Data
Rat; PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath
CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,829,1991
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
52.5
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Tralomethrin
CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
EPA-OGWDW
August 2009
Page 1080 of 1124
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
23,767
# PWSs/Sites/
Samples
115
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
15
% PWSs/Sites/
Samples with
detects
0
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:
Notes
Pesticide Data Program (USDA)
Pesticide; medication (HSDB)
Value
180 days
263,000
7.56
3.94E-10
0.08
1
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Tribromoacetic acid (TBAA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1081 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tribromoacetic acid (TBAA)
2695
75967
Attribute Scores 3-model Categorical Prediction
Potency Severity
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
mg/L
W/L
W/L
Prevalence Magnitude
9 8
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tribromoacetic acid (TBAA)
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1082 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
# PWSs/Sites
sampled
2,587
#with Detects
89
% PWSs/Sites
with detects
3.4
Mean value of
Detects
5.77
Maximum
value of
Detects
19
Median value of
Detects
5
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (no HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# PWSs/Sites/
Samples
40
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
10
Number of
States
% PWSs/Sites/
Samples with
detects
25
Units
States
States
States
Minimum value of
Detects (ug/L)
1
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects (ug/L)
15
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects (ug/L)
4
90% of
Detects (ug/L)
7.52
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Cancer:
Disinfection By-Product
Value
15 days
5.3
1.71
3.34E-09
200,000
26
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades slowly
-------
Tributyltin chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1083 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tributyltin chloride
11595
1461229
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0003
15
0.03
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1985
1986
Critical Effect
Based on IRIS RfD for TBT oxide, converted to
TBTchloride. Immunosuppression
Endocrine - other changes, Endocrine - changes in spleen
weight, Endocrine - changes in thymus weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
5 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 2W-C; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/paqe/year81,274,1985
Supplemental Data
Rat; 85JCAE "Prehled PrumysloveToxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1250,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
2.1
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tributyltin chloride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1084 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former pesticide; chemical intermediate (HSDB)
Value
6 days-35
weeks
90,800
60,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (HSDB)
-------
Trichloroacetonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1085 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Trichloroacetonitrile
7769
545062
Attribute Scores
Potency Severity
Prevalence Magnitude
8 6
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
mg/L
W/L
W/L
Teratogen
3-model Categorical Prediction
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Trichloroacetonitrile
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1086 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water
# PWSs/Sites
sampled
11,127
#with Detects
192
% PWSs/Sites
with detects
1.7
Mean value of
Detects
4.23
Maximum
value of
Detects
41.54
Median value of
Detects
0.8
90% of
Detects
99% of Detects
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (no HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Amount
Released
# Sam pies
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
Number of
States
% Samples w/
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500k
10K-500k
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Year
Maximum
value of
Detects
Units for Mag
data
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Notes
Notes
National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
Median value of
Detects
95% of
Detects
Units for Mag
data
Cancer:
Notes
Disinfection By-Product
Value
60 days
330
2.09
1.34E-06
715
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant
-------
Triethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1087 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triethanolamine
4260
102716
Attribute Scores
Potency Severity
5
Prevalence Magnitude
8 5
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
10
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD); Incomplete data for attribute scoring
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
2000
Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
23.33
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Triethanolamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1088 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Cancelled pesticide; chemical intermediate; in detergents; chelating agent (HSDB)
Value
7
-1
7.10E-13
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Triethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1089 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triethylene glyco
5015
112276
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3.57
7,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1987
Critical Effect
Liver -liver function tests impaired, Kidney, Ureter,
Bladder - other changes, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue
levels -transaminases
Liver - other changes, Kidney, Ureter, Bladder - other
changes
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; (GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
VolumefissueXpagefyear 52(1 2),77,1987)
Supplemental Data
Guinea pig; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,146,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
8.33
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Triethylene glycol
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1090 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ndustrial solvent; plasticizer; medication (HSDB)
Value
10
3.10E-11
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIO DEC)
-------
Trifluralin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1091 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trifluralin
11820
1582098
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.024
0.0075
0.0075
0.0075
0.75
25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1991
Critical Effect
Reduced body weight, decreased RBC & hemoglobin
evels, increased thrombocyte, methemoglobin,
cholesterol & triglyceride levels & increased liver
weight. Q1* 0.0058 (mg/kg-day)-1 . Group C. See CAR
ncreased liver weight, increase in methemoglobin
Liver - changes in liver weight
Prevalence Magnitude .,, .,, „
g 2 NL-NL;
HRL Ratio(s)
NC HRL/NAWQA 90%: 6,222
CARHRL/NAWQA90%:5
Notes
Reference Dose
Reference Dose; Basis = NOEL 0.75 mg/kg/day, dog, oral, UF = 100 (Hoechst Aktiengesellschaft, 1984a)
Reference Dose
Reference Dose; Basis = NOEL/LEL, dog, MF = 1 (Hoechst Aktiengesellchaft, 1984)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in dog 3Y-I; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.5
0.0077
0.0058
C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
2004
Kidney, bladder, thyroid
OPP
Emmerson etal., 1980
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW
Y
0.3
168
5
0.045
Y/N
Y/N
mg/L
W/L
W/L
mg/L
RAISHE
Drinking Water Equivalent Level
Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Trifluralin
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1092 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Sam pies
Amount
Released
22,263,693
0
9,341
# PWSs/Sites
sampled
380
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
5.34
% Samples with
detects
Number of
States
46
0
12
% PWSs/Sites
with detects
0.0005
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 6,222
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
1.74
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.006
Median value of
Detects
0.027
90% of
Detects
0.15
99% of Detects
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 185
Notes
Herbicide (HSDB)
Value
180 days
9,682
5.34
0.000103
0.184
3
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Trimellitic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1093 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimellitic anhydride
7816
552307
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.75
1,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1974
Critical Effect
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude ,,, _
8 3 NL'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information s available; hence LD 50 used for Potency/Severity
scoring.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Mouse; GTPZAB Gigiena Truda i Professiona 'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V«D Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 18(7),57,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
M/L
M/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For care nogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Trimellitic anhydride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1094 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Preparation of resins, adhesives, polymers, dyes; chem cal intermediate (HSDB)
Value
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
DF
Notes
DF = Degrades fast (HSDB)
-------
Trimethyl phosphate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1095 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethyl phosphate
7393
512561
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
40
70.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1997
Critical Effect
Peripheral Nerve and Sensation - sensory syndrome
diagnostic of central lesion, Behaviora - muscle
weakness, Blood - pigmented or nucleated red blood cells
Prevalence Magnitude
1 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level; Changes in thymus and kidney weight; hematological effects;kidney lesions;
nephropathy; decreased copulation rate, decreased fertility index and number of implantation sites;
ntrauterine mortality of embryos ncreased.
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 2.5Y-C; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 40,75,1997
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.037
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.946
Y/N
Y/N
W/L
W/L
Teratogen
CACART; RAISHE
CACART; UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Trimethyl phosphate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1096 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Gasoline additive; antioxidant (HSDB)
Value
7.644
-0.65
7.19E-09
500,000
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (BIODEG)
-------
Trimethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1097 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethylamine
2657
75503
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
40
397
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Intestinal lesions. Inflammation, ulceration, and
hyperplasia of squamous epithelium; edema of
submucosa in Gltract.
Prevalence Magnitude
7 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
280
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Trimethylamine
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1098 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Organic synthesis; corrosion inhibitor; fungicide (HSDB)
Value
29
0.16
890,000
52
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Trimethylolpropane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1099 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethylolpropane
2780
77996
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
800
13,700
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1967
Critical Effect
ncreased relative organ weight
Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea, Lungs, Thorax,
or Respiration - respiratory depression
Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information is available; hence NOEL used for Potency/Severity
scoring.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Mouse; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-
71. Discontinued. Volume(issue)/page/year 32(5), 288, 1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
5,600
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Trimethylolpropane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1100 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate for polymers (HSDB)
Value
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (BIODEG)
-------
Trinitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1101 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trinitrotoluene
5251
118967
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
0.0005
0.0005
0.0005
0.12
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1995
1995
1982
Critical Effect
Liver effects (increased relative & absolute liver
weight, hepatocytic cloudy swelling &
hepatocytom egaly)
Liver
Liver - changes in liver weight, Endocrine - changes in
spleen weight, Blood - changes in spleen
Prevalence Magnitude ,,, „
5 3 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = LOAEL 0.5 mg/kg-d, UF = 1000, dog (U.S. DOD, 1983)
Reference Dose; Oral, Int., UF = 1000, endpoint hepatic
Reference Dose; Basis = LOAEL, MF = 1 , UF = 1 000, dog (US DOD, 1 983)
Minimal Risk Level; Int. Oral, Endpoint = hepatic, UF = 1000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse 13W-C; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volume(issue)/page/year 9,565,1982
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.1
0.03
C
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1996
Bladder
Oral, rat (US DOD, 1984a)
Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.02
3.5
1
Y/N
Y/N
W/L
W/L
mg/L
EPA; RAISHE
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Trinitrotoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1102 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Explosive; chem cal intermediate (HSDB)
Value
1,834
1.6
5.48E-07
130
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimation (BIODEG)
-------
Triphenyl phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1103 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triphenyl phosphite
4154
101020
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
444
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
6 5 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
(GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1- 1936- Vo ume(issue)/page/year46(12),13,1981)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Triphenyl phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1104 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate; antioxidant/stabilizer; insect c
Value
38 days
6.62
2
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
de synergist (HSDB)
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Tris(2,3-dibromopropyl) phospha
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1105 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(2,3-dibromopropyl) phosphate
5620
126727
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
1 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2.3
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1
1999
Vol. 20, Suppl. 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
0.0152
Y/N
Y/N
W/L
W/L
CACART; IARC; OEHHA
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tris(2,3-dibromopropyl) phospha
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1106 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
0
500
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
0
1
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
No longer used in the US; former flame retardant (HSDB)
Value
60 days
5,100
4.29
2.60E-05
8
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Tris(2-chloroethyl) phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1107 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(2-chloroethyl) phosphite
6020
140089
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
1996
Critical Effect
Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Oral, rat (Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1 -3. New
York, NY: Van Nostrand Reinhold, 1996., p. 2691)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tris(2-chloroethyl) phosphite
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1108 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Flame retardant (HSDB)
Value
60 days
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/reca citrant (PBT)
-------
Tris(chloroethyl) phosphate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1109 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(chloroethyl) phosphate
5129
115968
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
10 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.3
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Brain - histological lesions. Also causes kidney tumors -
adenomas and carcinomas
3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/NREC SW MED: 21,000
CAR HRL/NREC SW MED: 25
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.014
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
2,100
2.5
Y/N
Y/N
W/L
W/L
RAIS
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Tris(chloroethyl) phosphate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1110 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (HRL/NREC SW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
85
# Sam pies
Amount
Released
# PWSs/Sites
sampled
19
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
57.6
% Samples with
detects
35
6.13
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer: 21,000
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.1
Median value of
Detects
0.18
0.195
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer: 25
Notes
Flame-retardant in plastics and urethanes (HSDB)
Value
60 days
301
1.44
2.54E-08
7,000
38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
BST = Biodegrades sometimes/recalcitrant (PBT)
-------
Undecane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1111 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Undecane
10679
1120214
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
100
2,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Salivation and decreased food consumption.
Prevalence Magnitude ,,,
83 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
700
Y/N
Y/N
M8/L
M8/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.
-------
Undecane
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1112 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
^Samples
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Gasoline constituent; research chemical; chemical intermediate (HSDB)
Value
8,7 days
6.5
1.93
0.0044
18
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (PBT)
-------
Urea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1113 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Urea
2307
57136
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
3,600
200
8,471
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2002
1977
1986
Critical Effect
Drowsiness and diuresis (nonadverse)
Behavioral - tremor, Behavioral - muse e weakness,
Gastrointestinal - alteration in gastric secretion
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
10 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPP NOAEL (TRED)
Lowest Observed Adverse Effect Level; JANSAG Journal of Animal Science. (American Soc. of Animal
Science, 309 W.Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year 45,566,1977
Supplemental Data
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 51(6), 8,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
25,200
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Urea
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1114 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; in fertilizers; as medication; de-icer; formerly in pest cide formulations (HSDB)
Value
8
-2.11
1.74E-12
545,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BF
Notes
BF = Biodegrades fast (BIODEG)
-------
Vanadium pentoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1115 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vanadium pentoxide
11141
1314621
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.009
0.009
0.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1988
1961
Critical Effect
Decreased haircystine content. Not an adverse effect.
Decreased Potency Score by one integer
Decreased hair cystine content
Behavioral - alteration of operant conditioning
Prevalence Magnitude ,,, ,,, „
58
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.89 mg/kg-d, rat, oral, UF = 100 (Stokinger et al., 1 953 )
Reference Dose
Reference Dose; Basis = NOAEL, MF= 1, rat, UF = 100 (Stokinger et al., 1953)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 26W-I; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 26(1 0), 6,1 961
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
63
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vanadium pentoxide
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1116 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1986
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Chemical intermed ate; catalyst (HSDB)
Value
133
2.97
156
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BST
Notes
assumed persistent; BST = Biodegradessometimes/recacitrant
-------
Vernolate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1117 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vernolate
12434
1929777
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.001
1,200
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986
1991
Critical Effect
Decreased body weight in parental animals
Decreased weight
Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
7 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = NOEL 1 mg/kg-d, UF = 1000, rat, oral (Stauffer Chemical Co., 1983)
Reference Dose
Reference Dose; Basis = NOEL/LEL, rat, whole body, MF = 1, UF = 1000 (Stauffer Chemical Co., 1983)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C321,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
7
Y/N
Y/N
W/L
W/L
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vernolate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1118 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
181,789
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
9
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
Former herbicide (HSDB)
Value
38
425
3.84
3.08E-05
90
16
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BSA
Notes
BSA = Biodegrades slow with acclimation (PBT)
-------
Vinyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1119 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyl acetate
4660
108054
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
1
0.1
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1966
Critical Effect
Altered weight
Behavioral - alteration of classical conditioning
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis = NOAEL, MF = 1 , UF = 100, rat, whole body (US EPA, 1 989)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1995
Vol. 63; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
7,000
Y/N
Y/N
W/L
W/L
1995
IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vinyl acetate
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1120 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
794
# Sam pies
Amount
Released
16,057
3,068,589
# PWSs/Sites
sampled
0
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
% Samples with
detects
Number of
States
8
35
% PWSs/Sites
with detects
Not Detected
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value
6.13
0.73
0.000511
20,000
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Not Detected
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Median value of
Detects
Not Detected
90% of
Detects
Not Detected
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate; in hairspray (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BFA
Notes
BFA = Biodegrades fast with acclimaton (BIODEG)
-------
Vinyl fluoride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1121 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyl fluoride
2618
75025
Attribute Scores
Potency Severity
Prevalence Magnitude
5 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
3-model Categorical Prediction
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1995
Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y/N
Y/N
W/L
W/L
CACART; IARC
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vinyl fluoride
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1122 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>1M-10M
XIM-10M
Polymer intermec
Value
1 5 days
24
1.2
0.12
12,99
61
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate (HSDB); gas
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
-------
Vinyltoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1123 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyltoluene
28159
25013154
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.006
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
Critical Effect
Nasal cavity- lesions
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis = LOAEL, MF = 1, UF = 1000, mouse, nasal cavity (US EPA, 1987)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
1994
Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
42
Y/N
Y/N
W/L
W/L
Teratogen
UMD
Drinking Water Equivalent Level
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.
-------
Vinyltoluene
CCL 3 Contaminant Information Sheet
EPA-OGWDW
August 2009
Page 1124 of 1124
OCCURRENCE DATA1
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# Sam pies
Amount
Released
# PWSs/Sites
sampled
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
% Samples with
detects
Number of
States
% PWSs/Sites
with detects
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
15
817
3.48
0.00785
89
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Median value of
Detects
99% of
Detects
Units for Mag
data
Cancer:
Notes
ate; insecticide component (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L
Degradation
Code
BS
Notes
BS = Biodegrades s ow (PBT)
------- |