vvEPA
   United States
   Environmental Protection
   Agency
 Contaminant Information Sheets for the
 PCCL Chemicals Considered for CCL 3

-------
Office of Water (4607M)
EPA815-R-09-014
August 2009
www.epa.gov/safewater

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EPA815-R-09-014                      Final CCL 3 Chemicals                                August 2009
EPA OGWDW                     Contaminant Information Sheets                           Page 1 of 1124

     Contaminant Information Sheets for the PCCL Chemicals Considered for CCL 3

This File contains Contaminant Information Sheets for 561 chemical contaminants on the
Preliminary Contaminant Candidate List (PCCL 3). These sheets summarize information about
the chemicals that were considered during the analysis for the development of the final third
Contaminant Candidate List (CCL 3).  The sheets are in alphabetical order. The first 106
Information Sheets are for the chemicals on the final CCL 3. (Note: there are 104 chemical
entries listed in the Federal Register Notice for the final CCL 3; cyanotoxins are listed as a
group. In this file, there are information sheets on three individual cyanotoxins that were
evaluated in the CCL 3 process (Anatoxin-a, Cylindrospermopsin, and Microcystin-LR)).
Following the CCL 3 chemicals, the Information Sheets for the remaining 455 chemicals on the
PCCL are presented in alphabetical order. Each information sheet is two pages in length.  There
is an index/bookmark in this PDF file that can be used to negotiate the file.  The bookmarks are
hyperlinked.  You can find the contaminant name in the bookmark list, click on it, and the
hyperlink will take you to that file.

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EPA815-R-09-014                          Final CCL 3 Chemicals                                      August 2009
EPAOGWDW                          Contaminant Information Sheets                                 Page 2 of 1124
                     This page intentionally left blank for double-sided printing

-------
1,1,1,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
  August 2009
Page 3 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,1,1 ,2-Tetrachloroethane
9105
630206
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.03
0.03
0.03












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
2006













Critical Effect

Mineralization of the kidneys in males, hepatic clear cell
change in females














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.1
0.026

C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1


1989


1989
1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

1
210
1
Y/N
Y/N
mg/L
ug/L
ug/L


2006







3-model Categorical Prediction
[_•?
HRL Ratio(s)
NC HRL/NCOD R1 90%: 67.7
CAR HRL/NCOD R1 90%: 0.323
Notes
Reference Dose
Reference Dose; Basis LOAEL =
89.3 mg/kg-d (NTP 1983)
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










EPA; RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    1,1,1,2-Tetrachloroethane
    CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
  August 2009
Page 4 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

16,956
24,127


31
51


0.18
0.21


0.06
0.2


9.2
18


0.59
0.5


3.1
1.55


9.2
18

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309


Amount
Released

36
12,088
# PWSs/Sites
sampled

4


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0.09


Number of
States

2
7
% PWSs/Sites
with detects

0.011


Units
States
States
States
Minimum value of
Detects

Non-cancer: 67.7
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.0644


Year
2004
2004

Maximum
value of
Detects

0.0275


0.0644


0.0644


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 0.323



Notes





Chemical intermed ate (NTP)
Value
60
93-399
2.66

2.70E-03
1,100
22
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
PBT; BST = biodegrades sometimes/recalcitrant







-------
1,1-Dichloroethane
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
  August 2009
Page 5 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,1-Dichloroethane
2647
75343
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.2












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



2001












Critical Effect



Decreased body weight gain












Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


0.0057
C

mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1990






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

1,400
6.14
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
77 Li
HRL Ratio(s)
NC HRL/NCOD R1 90%: 250
CAR HRL/NCOD R1 90%: 1.1
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; basis NOAEL 71 4 mg/kg-d, UF = 3,000; Muralidhara, et al, 2001 .
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,1-Dichloroethane
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
  August 2009
Page 6 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

20,483
24,808


233
184


1.14
0.74


0.01
0.0013


500
159


1.2
1


5.6
3.8


27
25

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,350


Amount
Released

63
17,368
# PWSs/Sites
sampled

135


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

3.103


Number of
States

3
5
% PWSs/Sites
with detects

0.008


Units
States
States
States
Minimum value of
Detects

Non-cancer: 250
Amount Range
>1M-10M
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



39


Year

2004
2004
Maximum
value of
Detects

0.05


0.316


5.6


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 1.1



Notes





Solvent (NTP)
Value
38
30
1.79

5.62E-03
5040
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation







-------
1,2,3-Trichloropropane
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
  August 2009
Page 7 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1 ,2,3-Trichloropropane
3817
96184
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.006
0.006
0.006
0.06





5.71
22.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
2006

1992





1987





Critical Effect

Alterations in clinical chemistry & reduction in RBC mass


Hepatic






Kidney, Ureter, Bladder - changes in bladder weight, Blood
- changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other esterases




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

7



mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

0.2
42
0.005
Y/N
Y/N
mg/L
ug/L
ug/L


2006







Prevalence Magnitude
3 6 Li
HRL Ratio(s)
NC HRL/NCOD R2 90%: 2.1
CAR HRL/NCOD R2 90% : 0.00025
Notes
Reference Dose
Reference Dose; NTP, 1983 ; rats; UF = 1,000; Basis NOAEL = 8 mg/kg-d
Reference Dose; F' 89
Reference Dose
Minimal Risk Level; Int-MRL; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER NOAEL
Lowest Observed Adverse Effect Level; 1 7 week oral study in rats; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-384,1993
Supplemental Data





HEAST




CACART, RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,2,3-Trichloropropane
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
  August 2009
Page 8 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

17,392
24,088


44
19


0.25
0.079


0.1
0.03


112
3,000


0.92
0.5


6
20


112
3,000

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
4,309


Amount
Released

282
9,053
43


Units
Ibs/yr
Ibs/yr
Ibs/yr
1.0


Number of
States

1
2
0.05


Units
States
States
States
2.92


Year

2004
2004
0.4


0.97


2.92


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Supplemental Water Data
Nominated data from NJDEP

HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
NJ study: Detected in excess of health-based drinking water guidance value in 30 of 2,640 private wells and 1 1 of approximately 260 community
water systems between 1999 and 2004 in NJ SOC Waiver Program sampling.

Non-cancer: 2.1
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.00025



Notes






Paint ingredient (NTP)
Value
38
77-95
2.27

3.43E-04
1,750
25
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
1,3-Butadiene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
  August 2009
Page 9 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,3-Butadiene
4578
106990
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
10 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


3.4
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-'






1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.0103
Y/N
Y/N

ug/L
ug/L






Teratogen List




3-model Categorical Prediction
L
HRL Ratio(s)
No Water Data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data








Vol.71; 1999

EPA, IARC, CACART, OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,3-Butadiene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 10 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

493
1,964,956
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

8
34
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rubber chemical (NTP)
Value
7-28
288
1.99

7.40E-02
735

Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = biodegrades fast with acclimation







-------
1,3-Dinitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 11 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,3-Dinitrobenzene
4045
99650
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0001
0.0001
0.0001
0.0005






1.73




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988
2006

1995











Critical Effect

Increased spleen weight


Hemato.






Endocrine - changes in spleen weight, Blood -
methemoglobinemia-carboxyhemoglobin




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1991






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
0.005
0.7

Y/N
Y/N
mg/L
ug/L
ug/L


2006



male



Prevalence Magnitude
1 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Cody etal., 1981; Rats; UF = 3,000; Basis NOAEL = 0.4 mg/kg-d
Reference Dose
Reference Dose; IRIS
Minimal Risk Level; Int-MRL; UF = 1 ,000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90 day oral study in rats; TOXID9 Toxicologist. (Soc. of
Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year
30,200,1996
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   1,3-Dinitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 12 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

2
528,962
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
1
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (HSDB)
Value
38
150
1.49

4.90E-08
533
37
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
1,4-Dioxane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 13 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1,4-Dioxane
5539
123911
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value




0.1











Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.3
0.011
0.027
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1

1999
1987


1987






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

700
3
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
9 8 L
HRL Ratio(s)
NC HRL/CAL DHS 90%: 92.1
CAR HRL/CAL DHS 90%: 0.395
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; ATSDR MRL-int = 0.6 mg/kg-d
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










CACART; EPA; IARC; OEHHA; RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,4-Dioxane
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
   August 2009
Page 14 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental water data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released

89,521
821,067
n
PWSs/Sites/Sa
mples
869


Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
89


Number of
States

7
22
%
PWSs/Sites/Sam
pies with
detects
10.2


Units
States
States
States
Minimum value of
Detects
0.001

Non-cancer: 92.1
Amount Range
>1M-10M
>1M-10M
Solvent (NTP); so
Value

1
-0.27

4.80E-06
1,000,000

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year

2004
2004
Maximum
value of
Detects
46.2






Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
2.1
90% of
Detects
7.6
Units
ug/L

Cancer: 0.395



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





vent stabilizer
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = biodegrades slowly







-------
17 alpha-Estradiol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 15 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
17 alpha-Estradio
81747
57910
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
9 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormonal response in post-menopausal
women










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N
mg/L
ug/L
ug/L










3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/Kolpin MAX: 4.7
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   17 alpha-Estradiol
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 16 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, et al., 2002

HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released


n
PWSs/Sites/Sa
mples
70






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects







Number of
States


%
PWSs/Sites/Sam
pies with
detects
5.7






Units
States
States
States
Minimum value of
Detects


Non-cancer: 4.7
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year


Maximum
value of
Detects
0.074
















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.03

90% of
Detects


Units for Mag
data
ug/L
Notes
National Surface Water Reconnaissance
Kolpin, D.W., et al., 2002. Env. Sci. STechnol., 36(6), pp. 1202-1211.

Cancer:







Pharmaceutical, hormone
Value
38

3.94


3.9
11
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
1-Butanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 17 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Butanol
2563
71363
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1







0.2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect

Hypoactivity, ataxia









Behavioral - somnolence (general depressed activity)




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1





1991






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

700

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude , „ ,
10 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. EPA, 1986; Basis NOAEL = 125 mg/kg-d, UF = 1,000; oral study in rats.
Reference Dose
Reference Dose; IRIS
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30 day oral study in rats; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
135,3122,2002
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   1-Butanol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 18 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released

22,011
17,648,846
# PWSs/Sites
sampled






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States

20
44
% PWSs/Sites
with detects






Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year

2004
2004
Maximum
value of
Detects
















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Paint solvent; chemical intermediate; food additive (HSDB)
Value

2.443
0.88

8.82E-06
63200

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades Fast







-------
2-Methoxyethanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 19 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methoxyethanol
4803
109864
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.003












Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



Reproductive effects












Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

21

Y/N
Y/N

ug/L
ug/L






Teratogen / developmental, male



Prevalence Magnitude
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Unpublished NTP study - Gulati, et al, 1990.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











UMD / CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Methoxyethanol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 20 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

14,390
153,774
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

3
16
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Consumer products; synthetic Cosmetics, Perfumes, Fragrances, Hair Preparations, Skin Lot on (NTP)
Value

1
-0.77

3.30E-07
1000000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades Fast with acclimat on







-------
2-Propen-1-ol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 21 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
2-Propen-1-ol
4596
107186
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.005

0.005







2.5



52
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect

Impaired renal function & increased relative liver,
spleen & kidney weights









Liver - liver function tests impaired, Blood - changes in
serum composition (e.g. TP, bilirubin, cholesterol),
Biochemical - Metabolism (Intermediary) - Plasma proteins
not involvinq coaqulation



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
8 8 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Carpanini et al., 1978; Rat; UF = 1,000; Basis NOAEL = 4.8 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; Rat; VCVGK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year -,121,1994
Supplemental Data


Rabbit; NTIS National Technical Information Serv ce. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0571508









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2-Propen-1-ol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 22 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

10,971
604,872
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

4
13
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Manufacture of flavorings, perfumes; chemical intermediate (HSDB)
Value

1.325
0.17

5.00E-06
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
3-Hydroxycarbofuran
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 23 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
3-Hydroxycarbofuran
25541
16655826
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00006














7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Inhibition of brain cholinesterase in pups - The RfD for
the parent covers the toxicity of the metabolite














Decreased body wt.
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.42

Y/N
Y/N

W/L
W/L










Prevalence Magnitude
2 7 Li
HRL Ratio(s)
NC HRL/NCOD R2 90%: 0.191
Notes
Reference Dose; Basis = BMDL10 0.03 mg/kg-d; UF = 500.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


PCBPBS Pesticde Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN
55802) V.1- 1971- Volume(issue)/page/year 3,435,1973









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   3-Hydroxycarbofuran
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
   August 2009
Page 24 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


12,700



18



0.14



1



66.3



2.2



2.2



66.3

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water

HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,539



Amount
Released


n
PWSs/Sites/Sa
mples


1



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
1
0.022



Number of
States


%
PWSs/Sites/Sam
pies with
detects
0
0.4
0.07



Units
States
States
States
Minimum value of
Detects



Non-cancer: 0.191
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.07



Year


Maximum
value of
Detects
0
0.062
0.07



0.07



0.07



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects


95% of
Detects


Units for Mag
data
ug/L
ug/L

Cancer:



Notes







Pesticide degradate
Value
38





43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation







-------
4,4'-Methylenedianiline
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
   August 2009
Page 25 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
4,4'-Methylenedianiline
4202
101779
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value




0.08






4.34




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




1998











Critical Effect




ntense liver degenerative lesions, hyperplasia of the
stroma






Liver - fatty liver degeneration, Kidney, Ureter, Bladder -
interstitial nephritis, Blood - normocytic anemia




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.25
1.6

2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1






1987





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


560
0.022
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,
7 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 5 week oral study in dogs; JJATDK JAT, Journal of Applied
Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year 11,367,1991
Supplemental Data





Slope factor withdrawn


Vol. 39, Suppl. 7; 1987

IARC, CACART, OEHHA, RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4,4'-Methylenedianiline
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 26 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

96,446
168,919
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

2
10
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; corrosion nhibitor; curing agent for polyurethanes (HSDB)
Value

4,950
1.59

1.58E-11
1,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
Acephate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 27 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acephate
31325
30560191
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0012
0.004

0.004

0.03





10




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1989



1990










Critical Effect
Brain ChE inhibition










Brain and Coverings - other degeneratve changes,
Autonomic Nervous System - sympathomimetic,
Biochemical - Metabolism (Intermediary) - amino acids
(including renal excretion)




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.4
0.0087

C

mg/L
(mg/kg-d)"1
(mg/kg-d)-1





1988




Liver

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


8.4
4
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 7 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 1.17
CAR HRL/SWC EEC: 0.556
Notes
Reference Dose; Basis = NOAEL 0.12 mg/kg-d; UF = 100.
Reference Dose; Basis = LOEL females = 0.15 mg/kg-d; LOEL males = 0.12 mg/kg-d; Adjusted Basis
Value = LOAEL 0.0004 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; ENVRAL Environmental Research. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1967- Volume(ssue)/page/year 43,342,1987
Supplemental Data










EPA; RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acephate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 28 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
2,462,354
0
20,751



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
35
0
5



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 7.2 ug/L
Ground water chronic: 0.02 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.17
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.556







nsecticide (HSDB)
Value

21.8
-0.85

5.02E-13
818,000

Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
Acetaldehyde
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 29 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetaldehyde
2622
75070
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











10




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral - changes in motoractivity (specific assay)




Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/DBP ICR MED: 3.15
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issueXpage/year PB234-882; 22-wk guinea pig study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1






1988
1999











Vol. 36, Suppl. 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

23.3

Y/N
Y/N

ug/L
ug/L






Teratogen list



IARC, EPA, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Acetaldehyde
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
   August 2009
Page 30 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF ICR




# PWSs/Sites
sampled
236




#with Detects
27




% PWSs/Sites
with detects
11.44




Minimum value of
Detects





Maximum
value of
Detects
18.3




Median value of
Detects
T.4




Mean value of
Detects
8.04




Units for Mag
data
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released

370,815
14,683,890
n
PWSs/Sites/Sa
mples
8

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3

% Samples with
detects

Number of
States

31
38
%
PWSs/Sites/Sam
pies with
detects
37.5

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
1
Non-cancer: 3.15
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
24

Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L

Notes





Notes


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L


National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
2
90% of
Detects
4
Units for Mag
data
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Pesticide; food additive; chemica intermediate (HSDB)
Value

1.498
-0.34

6.68E-05
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Acetamide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 31 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetamide
2411
60355
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


o.or

2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.5
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
7 9 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










CACART; OEHHA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetamide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 32 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

2,754
1,202,667
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

3
7
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; solubilizer; plasticizer; stabilizer (HSDB)
Value

5
-1.26

1.21E-08
2,250,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BF






Notes
BF = biodegrades fast







-------
Acetochlor
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 33 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor
32393
34256821
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02

0.02







5.45




Units
mg/kg-d
mg*g-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1993














Critical Effect

Salivation, increased ALT & omithine carbamyl
transferase; increases in triglyceride & decreased blood
glucose levels; histopathological changes in kidneys &
testes









Brain and Coverings - other degenerative changes, Blood -
methemoglobinemia-carboxyhemoglobin, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - dehvdroaenases




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


140

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQ 90% : 179
Notes
Reference Dose
Reference Dose; Basis NOAEL 2 mg*g-d; UF = 100. ICI, Inc., 1988a
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 42-day study in rat; PRKHDK Problemi na Khigienata. Problems in
Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, PI. Slaveikov 11, Sofia, Bulgaria) V.1- 1975-
Volume(issue)/page/year 15,96,1990
Supplemental Data










CACART

Drinking Water Equ valent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
        Acetochlor
        CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
   August 2009
Page 34 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water

CAL DHS
STORE!

HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529



Amount
Released
32,591,175

n
PWSs/Sites/Sa
mples


n
PWSs/Sites/Sa
mples
1,872
848
278



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
115
69
#with Detects
0
293
5.02



Number of
States
35

%
PWSs/Sites/Sam
pies with
detects
35.6
30.3
%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011



Units
States
States
States
Minimum value of
Detects


Minimum value of
Detects

0.026

Non-cancer: 179
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



30.4



Year
1997

Maximum value
of Detects
0.334
0.395
Maximum value
of Detects

21
0.032



0.784



8.49



Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes


Median value of
Detects


Median value of
Detects

0.022
95% of Detects
0.002
0.061
90% of Detects

1.5
Units
ug/L
ug/L
Units
ug/L
ug/L

Cancer:



Notes
Pesticide Pilot Mentoring Program (USGS/EPA)

Notes
Drinking water monitoring; http://www.cdph.ca.gov/certlic/
drinkingwater/Pages/Chemicalcontaminants.aspx






Herbicide (HSDB)
Value
4.3
98.5-239
3.03

5.4E-11
233
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast (half-life is for soil)







-------
Acetochlor ESA
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 35 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor ethanesulfonic acid (ESA)
79191
187022113
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
1 1
Scores based on parent
HEALTH EFFECTS DATA1 - See Acetochlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










23





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










Reduced body weights and body weight gains in both
sexes





Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



161

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 205 (NAWQA data for acetochlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR ACETOCHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
      Acetochlor ESA
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
   August 2009
Page 36 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data - FOR ACETOCHLOR - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data - FOR ACETOCHLOR - PARENT
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ACETOCHLOR ESA
POP finished water
FOR ACETOCHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529


Amount
Released
32,591,175

n
PWSs/Sites/Sa
mples
377
n
PWSs/Sites/Sa
mples
1,872
848
278


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
5
#with Detects
0
293
5.020


Number of
States
35

%
PWSs/Sites/Sam
pies with
detects
1.3
%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011


Units
States
States
States
Minimum value of
Detects
0.02
Minimum value of
Detects

0.026
Non-cancer: 205
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



30.4


Year
1997

Maximum value
of Detects
0.02
Maximum value
of Detects

21
0.032


0.784


8.49


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
FOR ACETOCHLOR - PARENT

Median value of
Detects

Median value of
Detects

0.022
95% of Detects

90% of Detects

1.5
Units
ug/L
Units
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USD A); 2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx

NAWQA data for acetochlor - parent



Pesticide degradate
Value







Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Acetochlor OA
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 37 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetochlor oxani ic acid (OA)
79193
194992444
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
1 1
Scores based on parent
HEALTH EFFECTS DATA1 - See Acetochlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










23





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










Reduced body weights and body weight gains in both
sexes





Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



161

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 205 (NAWQA data for acetochlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR ACETOCHLOR OA
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
      Acetochlor OA
      CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 38 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data FOR ACETOCHLOR - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,615



0



0



Not Detected



Not Detected



Not Detected



Not Detected



Not Detected



Ambient Water Occurrence Data FOR ACETOCHLOR - PARENT
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
TRI Release - total
Supplemental wate data FOR
ACETOCHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,72, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
5,529

Amount
Released
32,591,175


n
PWSs/Sites/Sa
mples
1,872
848
278

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
293
5.02

Number of
States
35


%
PWSs/Sites/Sam
pies with
detects
0
34.55
0.0011

Units
States
States
States
Minimum value of
Detects

0.026
Non-cancer: 205
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



30.4

Year
1997


Maximum value
of Detects

21
0.032

0.784

8.49

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
FOR ACETOCHLOR - PARENT


Median value of
Detects

0.022
90% of Detects

1.5
Units
ug/L
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

NAWQA data for acetochlor - parent



Pesticide degradate
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Acrolein
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 39 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acrolein
4581
107028
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0005

0.0005
0.0005






0.5




Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2003


12/1990











Critical Effect

Decreased survival


Hemato.






Liver - liver function tests impaired, Kidney, Ureter,
Bladder - other changes




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1






1995





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3.5

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
3 7 Li L
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 .03
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.05 mg/kg-d; UF = 100. Parent, et. al, 1S92a
Reference Dose
Reference Dose (IRIS)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week study in rat; VCVGK "Vrednie chemichescie veshestva,
galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year -,385,1994
Supplemental Data








Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Acrolein
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 40 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
1,108


Amount
Released

1
284,480
# PWSs/Sites
sampled

2


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0.18


Number of
States

1
16
% PWSs/Sites
with detects

1.3


Units
States
States
States
Minimum value of
Detects

Non-cancer: 1.03
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



3.4


Year

2004
2004
Maximum
value of
Detects

2.35


3.4


3.4


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Aquatic herbicide; rodenticide; industrial chemical (HSDB)
Value
120-180
3
-0.01

1.22E-04
212,000

Units
hours in water
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BF






Notes
pH = 7; BF = biodegradesfast







-------
Alachlor ESA
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 41 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Alachlor ethanesulfonic acid (ESA)
71246
142363539
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










157





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










ncreased incidence of clinical signs of toxicity in
males and females and decreased body weight gains
in males.





Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
0.04




mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,100

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,,,
93 NL
Scores based on parent HRL Ratio(s)
NC HRL/NAWQA 90% : 4,300 (NAWQA data for
alachlor - parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP - FOR ALACHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data




FOR ALACHLOR - PARENT







Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
    Alachlor ESA
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
   August 2009
Page 42 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data - FOR ALACHLOR PARENT
NAWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ALACHLOR ESA
POP finished water
POP finished water
FOR ALACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,166




Amount
Released



n
PWSs/Sites/Sa
mples
79
233
n
PWSs/Sites/Sa
mples
8,112
2,111
568




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
76
#with Detects
3
361
7.9




Number of
States



%
PWSs/Sites/Sam
pies with
detects
3.8
32.6
%
PWSs/Sites/Sam
pies with
detects
0.0003
17.1
0.0008




Units
States
States
States
Minimum value of
Detects
0.50
0.02
Minimum value of
Detects
0.24
0.0125
Non-cancer: 4,300
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



38.2




Year



Maximum
value of
Detects
0.50
1.44
Maximum
value of
Detects
14
10.78
0.015




0.256




3.33




Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes



Median value of
Detects


Median value of
Detects
4.29
0.06
95% of
Detects


90% of
Detects
11.09
0.55
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USD A); 2001
2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminant
s.aspx

NAWQA data for alachlor - parent



Pesticide degradate
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
AlachlorOA
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 43 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Alachlor oxanilic acid (OA)
79196
171262172
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.04




mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer




0.4
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
93 Li
Scores based on parent HRL Ratio(s)
CAR HRL/NAWQA 90% : 1 .56 (NAWQA data for
alachlor- parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data




FOR ALACHLOR - PARENT







Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   AlachlorOA
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
   August 2009
Page 44 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data - FOR ALACHLOR PARENT
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data - FOR
ALACHLOR OA
POP finished water
POP finished water
FOR ALACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,166



Amount
Released


n
PWSs/Sites/Sa
mples
137
411
n
PWSs/Sites/Sa
mples
8,112
2,111
568



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
21
#with Detects
3
361
r.9



Number of
States


%
PWSs/Sites/Sam
pies with
detects
0.07
5.1
%
PWSs/Sites/Sam
pies with
detects
0.0003
17.1
0.0008



Units
States
States
States
Minimum value of
Detects
0.50
0.121
Minimum value of
Detects
0.24
0.0125
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



38.2



Year


Maximum
value of
Detects
0.50
0.392
Maximum
value of
Detects
14
10.8
0.015



0.256



3.33



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects


Median value of
Detects
4.29
0.06
95% of
Detects


90% of
Detects
11.09
0.55
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer: 1.56



Notes
Pesticide Data Program (USDA); 2001
2002
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

NAWQA data for alachlor - parent



Pesticide degradate
Value







Units
ength of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
alpha-Hexachlorocyclohexane
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 45 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
alpha-Hexachlorocyclohexane
6535
319846
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value




0.008






1.2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




9/2003











Critical Effect




Hepatic






Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - hepatic microsomal mixed oxidase
(dealkylation, hydroxylation, etc.), Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
catalases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other oxidoreductases




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0006
6.3
2.7
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


56
0.006
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
4 3 Li
HRL Ratio(s)
NC HRL/NAWQA 90% : 949
CAR HRL/NAWQA 90%: 0.102
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Basis NOAEL 0.8 mg/kg-d; UF = 1 00.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
56,137,1991
Supplemental Data





IRIS




EPA; RAIS; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   alpha-Hexachlorocyclohexane
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 46 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,113



Amount
Released


# PWSs/Sites
sampled

21



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0.295



Number of
States


% PWSs/Sites
with detects

0.0004



Units
States
States
States
Minimum value of
Detects

Non-cancer: 949
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.21



Year


Maximum
value of
Detects

0.011



0.059



0.21



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 0.102



Notes





Component of benzene hexachloride (BHC) former insecticide (HSDB)
Value
1.2
641-1,995
3.8

6.70E-06
2

Units
years
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BST






Notes
hydrolysis only, pH = 7; BST = biodegrades sometimes/reca citrant







-------
Anatoxin-a
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 47 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Anatoxin-a
80772
64285069
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.0005







Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date








2006







Critical Effect








Mortality







Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3.5

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
9 8 L
Scores based on supplemental data HRL Ratio(s)
NC HRL/Cyano HABs MAX: -0.35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis NOAEL 0.5 mg/kg-d. Astrachan, N.B. and B.G. Archer. 1981.
Simplified monitoring of anatoxin-a by reverse-phase high performance liquid chromatography
and the sub-acute effects of anatoxin-a in rats. In: The Water Environment: Algal Toxins and
Health, W.W. Carmichael, Ed. Plenum Press, New York, NY. p. 437-446. Astrachan, N.B., B.G,
Archer and D.R. Hilbelink. 1980, Evaluation of thesubacutetoxicity and teratogenicity of anatoxin-
a. Toxicon. 18(5-6): 684-688.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Anatoxin-a
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 48 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Prev: UCMR1 Meeting summary; Mag:
CyanoHABs - The Florida Experience
HRL Ratios (HRL/CyanoHABs MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



%
PWSs/Sites/Sam
pies with
detects
4



Units
States
States
States
Minimum value of
Detects

Non-cancer: -0.35
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
~10









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data
ug/L
Cancer:



Notes
Prev: Lake Champlain, NY study; Mag: 2000 Florida study




Cyanobacterial toxin
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Aniline
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 49 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aniline
2438
62533
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.007



0.007



2.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







1993








Critical Effect



Blood- effects; Spleen-effects



spleen



Blood - pigmented or nucleated red blood cells, Blood -
methemoglobinemia-carboxyhemoglobin, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - other esterases




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.6
0.0057
0.0057
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1






1987



spleen

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


49
6
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
98 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Provisional value; 104-week chronic study in rat for aniline hydrochloride. CUT,
1982.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; CIIT.1982; Basis LOAEL 7.2 mg/kg-d; rat; UF = 1,000
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 12 week oral study in rats; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 24(7), 44,1 959
Supplemental Data





from IRIS


Vol. 27, Suppl. 7; 1987

EPA, CACART, OEHHA, RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Aniline
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 50 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

1,903
937,263
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

7
20
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemica ; as solvent; synthesis of explosives, rubber accelerators, isocyanates (HSDB)
Value

44.78
0.9

2.02E-06
36000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades Fast







-------
Bensulide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 51 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bensulide
9553
741582
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005














271
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Plasma & brain ChE inhibition, decreased body weight
gain














Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 6 Li
HRL Ratio(s)
NC HRL/SWC EEC: 0.224
Notes
Reference Dose; Basis = NOAEL 0.5 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C42,1991









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bensulide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 52 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
545,406





Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
34





Units
States
States
States



Year
1997











Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 158 ug/L
Ground water chronic: 1 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.224
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







Herbicide (HSDB)
Value




9.15E-09

15
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation







-------
Benzyl chloride
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 53 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Benzyl chloride
4107
100447
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











26.6




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Cardiac - other changes, Gastrointestinal - necrotic
changes, Related to Chronic Data - death




Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.02
0.17
0.17
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1989




Thyroid

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

62
0.2
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJIND8 JNCI, Journal of the National Cancer Institute.
(Washington, DC) V. 61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year
76,1231,1986; 26 week oral study in rats
Supplemental Data






2B from IARC
Lijinsky, 1986


CACART, EPA, RAIS, OEHHA, IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Benzyl chloride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 54 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, etal., 2006

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released

259
18,750
n
PWSs/Sites/Sa
mples
12


Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0


Number of
States

3
10
%
PWSs/Sites/Sam
pies with
detects
0


Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year

2004
2004
Maximum
value of
Detects
Not Detected






Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data

Notes
Krasner, etal., 2006. Env. Sci. &Technol., 40(23), pp. 7175-7185.

Cancer:







Chemical intermed ate (NTP)
Value

517.8
2.3

4.11E-04
20
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly







-------
Butylated hydroxyanisole
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
   August 2009
Page 55 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butylated hydroxyanisole
28160
25013165
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.249




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1959




Critical Effect











Liver - changes in liver weight




Prevalence Magnitude
8 4 NLi
HRL Ratio(s)
NC HRL/NREC NA GW MED: 0.484
CAR HRL/NREC NA GW MED: 146
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AJEBAK Australian Journal of Experimental Biology and
Medical Science. (Adelaide, S.A., Australia) V.1 -64, 1 924-86. Volume(issue);page/year 37,533,1 959
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.0002


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1



















Vol. 40, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


0.581
175
Y/N
Y/N

ug/L
ug/L










CACART; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Butylated hydroxyanisole
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
   August 2009
Page 56 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal.,2002
Focazio, etal., 2008
HRL Ratios (HRL/NREC NA GW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

85

# Sam pies

Amount
Released



n
PWSs/Sites/Sa
mples



2

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



2.4

% Samples with
detects
3
0.61
Number of
States



%
PWSs/Sites/Sam
pies with
detects





Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Non-cancer: 0.484
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
0.2
Not detected

0.1

Median value of
Detects
0.2
1.2



90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


99% of
Detects


Units for Mag
data
ug/L
ug/L
Cancer: 146



Notes
National Surface Water Reconnaissance; Kolpin, et al., 2002. Env. Sci.
&Technol.,36(6), pp. 1202-1211.
A national reconnaissance for Pharmaceuticals and other organic
wastewater contaminants in the United States ~ II. Untreated drinking
water sources. Focazio, etal., 2008. Sci. Tot. Env., 402(2-3), pp. 201-
216.




Food additive (antoxidant) (HSDB)
Value
38 days
1,390
3.5

1.17E-06

15
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Captan
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 57 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Captan
5825
133062
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.13


0.13

0.1





19.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999




1995










Critical Effect
Decreased pup body weight










Kidney, Ureter, Bladder - other changes in urine
composition, Blood - pigmented or nuceated red blood
cells, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - transaminases




Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0024
0.0035
0.0023

3
mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1987






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

910
14.6
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/SWC EEC: 84.3
CAR HRL/SWC EEC: 1.35
Notes
Reference Dose; Basis = NOEL 12.5 mg/kg-d; UF = 100

Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 38(9), 24,1 973
Supplemental Data











CACART; EPA; OEHHA; RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Captan
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
   August 2009
Page 58 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
3,992,782
15
2,938



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
39
3
6



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 10.8 ug/L
Ground water chronic: 0 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 84.3
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 1.35







Fungicide (NTP)
Value

862.2
2.8

7.01 E-09
5.1

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades Sometimes/Reca citrant. However, hydrolysis half-life s 4.9 hrs - 1 8.8 hrs @ pH 7 and 5, respectively.







-------
Chlorate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 59 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chlorate
24376
14866683
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03









5
1.4




Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










2005





Critical Effect
Thyroid hypertrophy and mineralization









Bone marrow hyperplasia; thyroid folicular hypertrophy
and mineralization
Blood - pigmented or nucleated red blood cells, Blood -
changes in erythrocyte (RBC) count, Nutritional and Gross
Metabolic - weight loss or decreased weight gain




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



mg/L
(mg/kg-d)"1
(mg/kg-d)"1
Not likely to be carcinogenic at
doses that do not alter thyroid












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/DBP ICR 90% : 0.656
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data - NTP Abstract for TR-51 7; 2-year rat study for sodium chlorate
Lowest Observed Adverse Effect Level; 1-year oral rat study fopr sodium chlorate; Journal of
Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466)
V.5(4)- 1984- Volume(issue)/page/year
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
   August 2009
Page 60 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR finished water



# PWSs/Sites
sampled
1,713



#with Detects
1,490



% PWSs/Sites
with detects
86.7



Mean value of
Detects
172



Maximum
value of
Detects
2,234



Median value of
Detects
120



90% of
Detects
320



99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released
7,261,557


n
PWSs/Sites/Sa
mples
116






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
66






Number of
States
16


%
PWSs/Sites/Sam
pies with
detects
56.9






Units
States
States
States
Median of Detects
110

Non-cancer: 0.656
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year
1997
2004
2004
Maximum of
Detects
747
















Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes








National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes
For sodium chlorate


Units for Mag data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.aspx

Cancer:




Agricultural defol ant or desiccant and in the production of CIO 2 (HSDB).
Value





1,000,000

Units
days
L/kg
unitless
cm3/g
atm-m3/mol
mg/L

Degradation
Code







Notes





For sodium chlorate


-------
Chloromethane (Methyl chloride)
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 61 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloromethane (Methyl chloride
2605
74873
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.004













Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date


2006













Critical Effect


Mild neurological effects in humans occupationally
exposed to Chloromethane













Cancer Data
EPA Lifetime Cancer Risk, ICT*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.013

D
3
mg/L
(mg/kg-d)-'
(mg/kg-d)"1



1981

2001
1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
28
2.69
Y/N
Y/N
mg/L
ug/L
ug/L


2006


developmental
Teratogen



Prevalence Magnitude , „ ,
87 L' L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 2.15
CAR HRL/NCOD R1 90%: 0.207
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data





CUT, 1981


Vol. 41,Suppl. 7, Vol. 71; 1999

CACART, RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Chloromethane (Methyl chloride)
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
   August 2009
Page 62 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NGOD Round 2 finished water
NIRS finished water

20,246
23,478


248
528


1.22
2.25


0.01
0.00073


550
312


1.9
1.4


13
5


120
29

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasneretal., 2006

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,959



Amount
Released

1,539
1,733,197
n
PWSs/Sites/Sa
mples
11,984
12
356



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
247
1
8.99



Number of
States

10
26
%
PWSs/Sites/Sam
pies with
detects
2.1
8
0.007



Units
States
States
States
Minimum value of
Detects
0.25


Non-cancer: 2.15
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002



21



Year

2004
2004
Maximum
value of
Detects
46

0.04



0.1



0.58



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.7
ND
90% of
Detects
2

Units for Mag
data
ug/L
ug/L

Cancer: 0.207



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Krasner, etal., 2006. Env. Sci. &Technol., 40(23), pp. 7175-7185.





Foaming agent; in organic synthes s (HSDB); naturally-occurring gas
Value
15
14
0.91

8.82E-03
5320
43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = Biodegrades Slowly







-------
Clethodim
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 63 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Clethodim
76719
110429624
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01




0.01









1,360
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect
Increased liver weights increased liver enzymes and
iver histopathology














Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



70

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 6 Li
HRL Ratio(s)
NC HRL/SWC EEC: 9.21
Notes
Reference Dose; Basis = NOEL 1 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Oral study in rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C272,1991









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Clethodim
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 64 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
670,721





Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
39





Units
States
States
States



Year
1997











Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data:
OPP Estimated Environmental Concentration
Surface water chronic: 7.6 ug/L
Ground water chronic: 0.49 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 9.21
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







Herbicide; pesticide degradate
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Cobalt
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 65 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cobalt
18870
7440484
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.02
0.01


0.0014








Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




2004


2000








Critical Effect




Blood-increased hemoglobin, polycythemia;
respiratory-effects on lung function


Heart








Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1






1991





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,,, _
4 8 NL'
HRL Ratio(s)
NCHRL/NIRS90%:6.67
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; 'multiple studies as cited in ATSDR, 1992; UF = 30; human study; RIVM; Basis
LOAEL = 0.04 mg/kg-d
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data








Vol. 52; 1991; NB: Evaluated as a group; Cancer classifications were used for screening, but no related
quantitative cancer risk data were identified for potency scoring.

IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cobalt
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
   August 2009
Page 66 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



3



0.303



6.4



10.6



9.7



10.5



10.6
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,297


Amount
Released

1,272
786,491
# PWSs/Sites
sampled

782


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

23.7


Number of
States

17
38
% PWSs/Sites
with detects

0.007


Units
States
States
States
Minimum value of
Detects

Non-cancer: 6.67
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



684


Year

2004
2004
Maximum
value of
Detects

0.22


3.91


53.2


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for cobaltous chloride: Formerly in medicines; as germicide (HSDB); naturally-occurring
Value





534,200

Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BST






Notes
assumed persistent; All use and env. fate data are for cobaltous chloride; BST = biodegrades sometimes/reca citrant







-------
Cumene hydroperoxide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 67 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cumene hydroperoxide
2927
80159
Attribute Scores
Potency Severity
4 9
Prevalence Magnitude
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











32.7



382
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Mortality




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



76.4

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AIHAAP American Industrial Hygiene Association Journal.
(AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issueXpage/year
19,205,1958; 7 week oral study in rats
Supplemental Data


Oral study in rats









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cumene hydroperoxide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 68 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

96
443,772
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
15
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (HSDB)
Value


2.16

4.71 E-08
13,900
25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation; PBT







-------
Cylindrospermopsin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 69 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cylindrospermopsin
81115
143545908
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.00003







Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg*g-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date








2006







Critical Effect








Increased kidney weight







Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.21

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „
5 10 L'
Scores based on supplemental data HRL Ratio(s)
c^notoxTsuryr00" *"** °" ""** NC HRL/CyanoHABs MAX: -0.0021
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis LOAEL 60 ug/kg-d; NOAEL 3 ug/kg-d. Humpage, A.R. and I.R.
Falconer. 2003. Oral toxicity of the cyanobacterial toxin Cylindrospermopsin in male Swiss albino
mice: Determination of no observed adverse effect level for deriving a drinking water guideline
value. Environ. Toxicol. 18(2):94-103.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cylindrospermopsin
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 70 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CyanoHABs - The Florida Experience
UCMR 1 Meeting summary

HRL Ratios (HRL/CyanoHABs MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States



%
PWSs/Sites/Sam
pies with
detects
Not Available
Not Available




Units
States
States
States
Minimum value of
Detects



Non-cancer: -0.0021
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
-100
90










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects



99% of
Detects



Units for Mag
data
ug/L
ug/L

Cancer:



Notes
2000 Florida study
Florida survey






Cyanobacterial toxin
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Dicrotophos
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 71 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dicrotophos
6098
141662
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00007
0.0001

0.0001











11
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986














Critical Effect
Decreased plasma, RBC & brain ChE activity
Decreased body weight













Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



Suggestive
evidence

mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.49

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 2.45
Notes
Reference Dose; Basis = LOAEL 0.02 mg/kg-d; UF = 300.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa,
Ont, Canada) Volume(issue)/page/year 6,196,1973




OPP; no quantif cation




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dicrotophos
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
   August 2009
Page 72 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
359,726


n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
13


%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year



Maximum
value of
Detects
0
0
Surface water chronic: 0.2 ug/L









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
0
0
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA); 2002
2002
Ground water chronic: 0.005 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 2.45
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







nsecticide (HSDB)
Value

366.2
-0.49

5.05E-11
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = Biodegrades Slowly







-------
Dimethipin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 73 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dimethipin
36818
55290647
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0218
0.02

0.02

0.02










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1986




1999










Critical Effect
Kidney, lungs, duodenum, liver, glandular stomach,
heart, aortic artery & testes toxicity. Decreased body
weight gain.
ncreased absolute and relative liver weight














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



C

mg/L
(mg/kg-d)"1
(mg/kg-d)-1





1987






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



153

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
8 5 Li
HRL Ratio(s)
NC HRL/GWC EEC: 1.55
Notes
Reference Dose; Basis = NOEL 2.1 8 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dimethipin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 74 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
282,458
0
250



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
14
0
1



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 7.3 ug/L
Ground water chronic: 99 ug/L

HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.55
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







Herbicide; plant growth regulator (HSDB)
Value

27.41
-0.17

2.30E-11
4,600
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = biodegrades slowly with acclimation; PBT







-------
Dimethoate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 75 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dimethoate
2413
60515
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0022
0.0002

0.0002

0.002





3




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2007
1988



1996










Critical Effect
Brain cholinesterase inhibition
Brain cholinesterase nhibition









Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



C

mg/L
(mg/kg-d)"1
(mg/kg-d)"1





2006






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

15.4

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude , „ ,
10 7 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 0.655
Notes
Reference Dose; OPP RED
Reference Dose; Basis NOEL 0.05 mg/kg-d; UF = 100. American Cyanamid Co., 1986a
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level - 52-week study in rat; BJIMAG British Journal of Industrial
Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
Volume(issue)/page/year21,52,1964
Supplemental Data







OPP



UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Dimethoate
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
   August 2009
Page 76 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water

CAL DHS
STORE!




Amount
Released
1,896,947
2,615
31,480
n
PWSs/Sites/Sa
mples


n
PWSs/Sites/Sa
mples
7,238
890
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
4

#with Detects
0
14




Number of
States
44
2
4
%
PWSs/Sites/Sam
pies with
detects
1.3

%
PWSs/Sites/Sam
pies with
detects
0
1.57




Units
States
States
States
Minimum value of
Detects


Minimum value of
Detects

0.055




Year
1997
2004
2004
Maximum
value of
Detects
0.022

Maximum
value of
Detects

0.21
Surface water chronic: 23.5 ug/L
Non-cancer: 0.655
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002















Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes


Median value of
Detects


Median value of
Detects

0.148
95% of
Detects


90% of
Detects

0.198
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

Ground water chronic: 0.044 ug/L
Cancer:







Pesticide (NTP)
Value
8
5.2-36
0.78

2.43E-10
23,800
36
Units
weeks
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = biodegrades slowly with acclimation







-------
Disulfoton
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 77 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Disulfoton
6423
298044
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00013
0.00004
0.0001
0.00004
0.00006
0.0003





0.06




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2002
1986
2006

08/1995
1991










Critical Effect
Plasma, RBC, brain & corneal ChE inhibition










Brain and Coverings - other degenerative changes, Blood -
other changes, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - true cholinesterase




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification



E

mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.0035
0.91

Y/N
Y/N
mg/L
ug/L
ug/L


2006







Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NCHRL/NAWQA90%: 1.1
Notes
Reference Dose; Basis = NOAEL 0.013 mgrtsg-d; UF = 100.
Reference Dose; Basis = LOAEL 0.04 mg/kg-d; UF = 1 ,000.
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology. (Academic Press,
Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
Volume(issue)/page/year35,101,1997
Supplemental Data, ITER







Cancer classifications were used for screening, but no related quantitative cancer risk data were identified for
potency scoring.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
      Disulfoton
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
   August 2009
Page 78 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300



0



0



Not Detected



Not Detected



Not Detected



Not Detected



Not Detected



Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118


Amount
Released
1,196,066


n
PWSs/Sites/Sa
mples


17


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
0.24


Number of
States
33


%
PWSs/Sites/Sam
pies with
detects
0
0
0.002


Units
States
States
States
Minimum value of
Detects



Non-cancer: 1.1
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



3.81


Year
1997


Maximum value
of Detects
Not Detected
Not Detected
0.02


0.826


3.81


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of Detects
Not Detected
Not Detected
Units for Mag
data



Cancer:



Notes
Pesticide Pilot Mentoring Program (USGS/EPA); 2002
2002





nsecticide (HSDB)
Value
7-41
684-14,013
4.02

2.20E-06
16.3
17
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades Slowly







-------
Diuron
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 79 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Diuron
6583
330541
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003
0.002
0.003
0.002







1.75




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
2006













Critical Effect
Hemolytic anemia & compensatory hematopotesis
(decreased erythrocyte count, hemoglobin level, etc).










Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Liver - changes in liver weight, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases




Cancer Data
EPA Lifetime Cancer Risk, 104
EPA OPP Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0191

Known/Likely

mg/L
(mg/kg-d)-1
(mg/kg-d)-1



2003

2003






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
21
1.83
Y/N
Y/N
mg/L
ug/L
ug/L


2006



Teratogen



Prevalence Magnitude
4 7 NL!
HRL Ratio(s)
NCHRL/UCMR90%: 10
CAR HRL/UCMR 90%: 0.871
Notes
Reference Dose; du Pont, 1364a; Basis = LOAEL 1 .0 mg/kg-d; UF = 300.
Reference Dose; Basis NOEL 0.625 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year36,76,1990
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.


EPA, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Diuron
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
   August 2009
Page 80 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
298


1


0.34


2.1


2.1


2.1


2.1


2.1


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,552



Amount
Released
4,370,448
10
798
n
PWSs/Sites/Sa
mples
270


319



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
117
13
7.00



Number of
States
39
2
5
%
PWSs/Sites/Sam
pies with
detects
0.4
37.5
5.8
0.0004



Units
States
States
States
Minimum value of
Detects
0.058


Non-cancer: 10
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002



23.3



Year
1997
2004
2004
Maximum
value of
Detects
0.058
0.54
0.079
0.09



0.915



8.4



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects



95% of
Detects

0.319
0.079
Units
ug/L
ug/L
ug/L
Cancer: 0.871



Notes

Pesticide Data Program (USDA); 2002





Herbicide (HSDB
Value

224-879
2.68

5.8E-10
36.4
15
Units
months
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BST






Notes
BST = biodegrades sometimes/recalcitrant







-------
Equilenin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 81 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Equilenin
81750
517099
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
9 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormonal response in post-menopausal
women










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N
mg/L
ug/L
ug/L










3-model Categorical Prediction
L?-L
HRL Ratio(s)
NC HRL/Kolpin MAX: 1.26
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Equilenin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 82 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal., 2002

HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released


n
PWSs/Sites/Sa
mples
70






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects







Number of
States


%
PWSs/Sites/Sam
pies with
detects
2.8






Units
States
States
States
Minimum value of
Detects


Non-cancer: 1.26
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year


Maximum
value of
Detects
0.278
















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.14

90% of
Detects


Units for Mag
data
ug/L
Notes
National Surfac
Sci.&Technol
e Water Reconnaissance; Kolpin, etal., 2002. Env.
36(6), pp. 1202-1211.

Cancer:







Pharmaceutical, hormone
Value


3.93


1.52

Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Equilin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 83 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Equilin
81748
474862
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
8 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormonal response in post-menopausal
women










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N
mg/L
ug/L
ug/L










3-model Categorical Prediction
L?-L
HRL Ratio(s)
NC HRL/Kolpin MAX: 2.38
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Equilin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 84 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal., 2002

HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released


n
PWSs/Sites/Sa
mples
ro




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States


%
PWSs/Sites/Sam
pies with
detects
1.4




Units
States
States
States
Minimum value of
Detects


Non-cancer: 2.38
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year


Maximum
value of
Detects
0.147










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.147

90% of
Detects


Units for Mag
data
ug/L
Notes
National Surfac
Sci. & Technol
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.

Cancer:







Pharmaceutical, hormone
Value
38

3.35


1.41
13
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Erythromycin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 85 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Erythromycin
75632
114078
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.0007






66.7



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





2006










Critical Effect





Inhibition of beneficial gastrointestinal bacteria










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

4.9

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 4
HRL Ratio(s)
NC HRL/NREC MAX: 2.88
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)











UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Erythromycin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 86 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Focazio, etal., 2008

HRL Ratios (HRL/NREC MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

104
90

Amount
Released



n
PWSs/Sites/Sa
mples



22
0

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



21.5
0.0

Number of
States



%
PWSs/Sites/Sam
pies with
detects




Not detected

Units
States
States
States
Minimum value of
Detects


Non-cancer: 2.88
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




1.7
Not detected

Year



Maximum
value of
Detects
0.3


0.1
Not detected



Not detected



Not detected

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


90% of
Detects


Units for Mag
data
ug/L
Notes
Drinking water monitoring; Focazio, etal., 2008. Sci.Tot. Env. 402(2-3),
pp. 201-216.

Cancer:







Pharmaceutica , antibiotic
Value
180

3.06

5.20E-29

6
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Estradiol (17-beta estradiol)
CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
   August 2009
Page 87 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estradiol (17-beta estradiol)
2130
50282
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormona response in post-menopausal women










Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


39

1
mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.35
0.0009
Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude ,
10 5 L
HRL Ratio(s)
NC HRL/Kolpin MAX: 1.75
CAR HRL/Kolpin MAX: 0.0045
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










IARC, CACART, OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Estradiol (17-beta estradiol)
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                EPA-OGWDW
   August 2009
Page 88 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples


85




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects







Number of
States


%
PWSs/Sites/Sam
pies with
detects
0.0

10.6




Units
States
States
States
Minimum value of
Detects
Not detected


Non-cancer: 1.75
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
Not detected
0.0064
0.2












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
Not detected

0.16
90% of
Detects
Not detected


Units for Mag No(es
data
ug/L
ug/L
ug/L
Cancer: 0.0045



Finished Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
National Surface Water Reconnaissance; Kolpin, et al., 2002. Env.
Sci.&Techno ., 36(6), pp. 1202-1211.




Pharmaceutical, hormone
Value
38

4.01

6.40E-11
3.6
11
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Estriol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 89 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estriol
75525
50271
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
10 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormonal response in post-menopausal
women










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.35

Y/N
Y/N
mg/L
ug/L
ug/L










3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/Kolpin MAX: 6.86
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Estriol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
   August 2009
Page 90 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples


70



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States



%
PWSs/Sites/Sam
pies with
detects
0.0
0.0
21.4



Units
States
States
States
Minimum value of
Detects
Not detected
Not detected

Non-cancer: 6.86
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
Not detected
Not detected
0.051









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not detected
Not detected
0.019
90% of
Detects
Not detected
Not detected

Units for Mag
data
ug/L
ug/L
ug/L
Cancer:



Notes
Finished Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al, 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
National Surfac
Sci. & Techno .
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.




Pharmaceutica , hormone
Value
38

2.45

1.33E-12
441
17
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Estrone
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 91 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Estrone
2210
53167
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JECFA ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.00005










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect





Estrogenic hormonal response in post-menopausal
women










Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.35

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
9 3 Li
HRL Ratio(s)
NC HRL/Swartz MAX: 2.92
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake for E2
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Estrone
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
   August 2009
Page 92 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Boyd, etal.,2003
Snyder, 2008
Kolpin.etal., 2002
Swartz, etal.,2006
HRL Ratios (HRL/Swartz MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



n
PWSs/Sites/Sa
mples


70





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects








Number of
States



%
PWSs/Sites/Sam
pies with
detects


7.1





Units
States
States
States
Minimum value of
Detects
Not detected



Non-cancer: 2.92
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects
Not detected
0.002
0.112
0.12












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not detected

0.027

90% of
Detects
Not detected



Units for Mag No(es
data
Finished Drinking Water; Boyd, etal, 2003. Sci. Tot. Env. 311(1-3): pp.
135-149.
ug/L
ug/L
ug/L
Cancer:



Raw Drinking Water; Snyder, et al, 2008. Removal of Endocrine
Disrupters and Pharmaceuticals during Water Treatment. In: Fate of
Pharmaceuticals in the Environmental and in Water Treatment Systems.
National Surfac
Sci. & Technol
e Water Reconnaissance; Kolpin, et al., 2002. Env.
36(6), pp. 1202-1211.
Ambient Water (SW/GW); Swartz, et al., 2006. Env. Sci. & Technol.
40(16): pp. 4894-4902.




Pharmaceutical, hormone
Value
38

3.13

3.80E-10
30
13
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Ethinyl Estradiol
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
   August 2009
Page 93 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethinyl Estradiol (17-alpha ethynyl estradiol)
2327
57636
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.04

0.015
0.0005



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001

1981




Critical Effect











Hematalogical effects

Increased serum levels of alanine aminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GGT).




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.28

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 4 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.337
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, etal., 1981 as cited in Maier and Hermann, 2001.
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)










CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethinyl Estradiol
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 94 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Snyder, etal., 2007
Kolpin, etal., 2002
HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples


70




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects







Number of
States


%
PWSs/Sites/Sam
pies with
detects
0.0
0.0
5.7




Units
States
States
States
Minimum value of
Detects (ug/L)
Not detected
Not detected

Non-cancer: 0.337
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects (ug/L)
Not detected
Not detected
0.273












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects (ug/L)
Not detected
Not detected
0.094
90% of
Detects (ug/L)
Not detected
Not detected

Units for Mag
data
ug/L
ug/L
ug/L
Cancer:



Notes
Finished Drinking Water; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Raw Drinking Water; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Response to Comment on National Surface Water Reconnaissance
Kolpin et al., 2002: Env. Sci. & Technol., 36(18), pp. 4007-4008.




Pharmaceutical, hormone
Value
60

3.67

7.94E-12
11.3
9
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Ethoprop
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 95 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethoprop
22682
13194484
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001




0.0004









33
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1999










Critical Effect
Plasma ChE inhibition, Q1* 0.0281 (mg/kg-day)-1 -
Likely.














Behavioral - changes in motor activity (specific assay),
Behavioral - muscle contraction or spasticity
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.12


0.0281
Likely

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


0.7
1.25
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,,, _
7 3 NL'
HRL Ratio(s)
NC HRL/NAWQA 90%: 7.29
CAR HRL/NAWQA 90%: 13
Notes
Reference Dose; Basis = NOAEL 0.01 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


HBPTO Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year 1 ,693,2001




OPP RED and Ethoprop pesticide tolerances: 73 FR 53725, Spetember 17, 2008



CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethoprop
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
   August 2009
Page 96 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118




Amount
Released
1,010,807
0
77,786
n
PWSs/Sites/Sa
mples


84




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
1.18




Number of
States
28
0
4
%
PWSs/Sites/Sam
pies with
detects
0
0
0.002




Units
States
States
States
Minimum value of
Detects


Non-cancer: 7.29
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.95




Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
0.011




0.096




0.8




Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer: 13



Notes
Pesticide Pilot Mentoring Program (USGS/EPA); 2001
2001




nsecticide (HSDB)
Value
75-133
70-120
3.59

1.70E-07
750

Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
hydrolysis only: BST = biodegrades sometimes/recalcitrant







-------
Ethylene glycol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
   August 2009
Page 97 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene glycol
4599
107211
Attribute Scores
Potency Severity
3 9
Prevalence Magnitude
10 10
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

2
2
2
0.8


0.05



600




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
2006

2007


2000








Critical Effect

Kidney toxicity. Increased mortality, neutrophil count,
kidney hemoglobin & hematocrit, chronic nephritis


ncreased total malformations and incidence of extra rib 14
in developmental study


Kidney



Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in tubules (including acute renal failure, acute tubular
necrosis), Related to Chronic Data - death




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1987






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
70
14,000

Y/N
Y/N
mg/L
ug/L
ug/L


2006



Teratogen




3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; DePass et al., 1986a; UF = 100; Rat; Basis NOAEL = 200 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Gaunt etal., 1974; UF = 1,000; Rat
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2 year oral study in rate; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year3,229,1965
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethylene glycol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
   August 2009
Page 98 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

576,990
10,076,483
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

31
49
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Antifreeze; cancelled pesticide; synthetic chemical used in textile manufacture (NTP)
Value

1
-1.36

6.00E-08
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
Ethylene Oxide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
   August 2009
Page 99 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene Oxide
2635
75218
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

1.02
0.31

1
mg/L
(mg/kg-d)-1
(mg/kg-d)-'






1994





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.113
Y/N
Y/N

ug/L
ug/L






Teratogen; Developmental



Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data





HEAST




CACART; RAIS; OEHHA; EPA; IARC
UMD; CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethylene Oxide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 100 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

4,761
374,110
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

4
38
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fumigant (NTP); gas
Value

1.435
-0.3

1.48E-04
1,000,000
43
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BS






Notes
PBT; BS = biodegrades slowly







-------
Ethylene thiourea
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 101 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethylene thiourea
3836
96457
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002
0.00008
0.00008
0.00008

0.004





1.34




Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1991
2006


1993










Critical Effect
Thyroid toxicity
ncreased incidence of thyroid hyperplasia









Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.006
0.06
0.045
B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1988
2001





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.003
1.4
0.06
Y/N
Y/N
mg/L
W/L
W/L


2006



Teratogen; Developmental



Prevalence Magnitude
4 1 NLi
HRL Ratio(s)
NC HRL/GWC EEC: 6.67
CAR HRL/GWC EEC: 0.286
Notes
Reference Dose
Reference Dose; Basis LOAEL 0.25 mg/kg-d. Graham etal., 1975
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 8-week study in rat; JAFCAU Journal of Agricultural and Food
Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn.,
Washington, DC 20037) V.1- 1953- Volume(issue)/page/vear 21,324,1973
Supplemental Data




OPP
OPP




EPA; RAIS; OEHHA; IARC; CACART
UMD; CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Ethylene thiourea
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 102 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total




Amount
Released

5
299




Units
Ibs/yr
Ibs/yr
Ibsfyr




Number of
States

1
4




Units
States
States
States




Year

2004
2004












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 0.1 ug/L
Ground water chronic: 0.21 ug/L

HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 6.67
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.286







Pesticide (NTP)
Accelerator; industrial intermediate (HSDB)
Value
15
6.5
-0.66

3.40E-07
20,000
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly




(at 30 C)


-------
Fenamiphos
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 103 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Fenamiphos
27401
22224926
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0001
0.00025
0.0001
0.00025

0.0008










Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986
2006


1997










Critical Effect
Plasma ChE inhibition.
Cholinesterase inhibit on














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



E

mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1988






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.0035
0.7

Y/N
Y/N
mg/L
ug/L
ug/L


2006







Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 0.051
Notes
Reference Dose; Basis = NOAEL 0.01 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 0.025 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring. OPP changed cancer classification from D to E.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Fenamiphos
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 104 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
726,675


n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
14


%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year
1997


Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 13.7 ug/L
Non-cancer: 0.051
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic: 0.47 ug/L
Cancer:







nsecticide (HSDB)
Value

225.1
3.23

1.21E-09
329
12
Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BSA






Notes
BSA = biodegrades slowly with acclimation; PBT







-------
Formaldehyde
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 105 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Formaldehyde
2119
50000
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.2
0.2
0.2
0.2






12.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990
2006

1999











Critical Effect

Reduced weight gain, histopathology in rats.
Decreased absolute heart, liver, testes & kidney
weights. Increased relative brain, testes weights.


Gastro.






Liver - other changes, Blood - changes in spleen




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



B1
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1





1993
1995





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
7
1,400

Y/N
Y/N
ug/L
ug/L
ug/L


2006



Teratogen



Prevalence Magnitude
10 8
HRL Ratio(s)
NC HRL/DBP ICR MED: 184
Notes
Reference Dose
Reference Dose; Basis = NOAEL 15 mg/kg-d; UF = 100. Til etal., 1989
Reference Dose
Reference Dose
Minimal Risk Level; Basis = NOAEL 15 mg/kg-d; ATSDR MRL-int = 0.3 mg/kg-d (Til etal., 1989).
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Bandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,339,1994
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.


CACART; EPA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Formaldehyde
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 106 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR




# PWSs/Sites
sampled
227




#with Detects
126




% PWSs/Sites
with detects
55.5




Minimum value of
Detects
5




Maximum
value of
Detects
30.6




Median value of
Detects
7.6




99% of
Detects
29.7




Units for Mag
data
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total

HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

326,298
26,992,234



Units
Ibs/yr
Ibs/yr
Ibs/yr



Number of
States

31
46



Units
States
States
States

Non-cancer: 184
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004









Units for Mag
data

ug/L
ug/L
ug/L

Notes





Notes


ug/L
ug/L
ug/L
ug/L
ug/L


National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes




Cancer:







Naturally-occurring fungicide (NTP); Disinfection by-Product; gas
Value

1
0.35

3.38E-07
400,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades Fast with Acclimation







-------
Germanium
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 107 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Germanium
18876
7440564
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.318




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis)




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.744

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
4 10 Li
HRL Ratio(s)
NC HRL/NIRS 90% : 0.003
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJMDAT Japanese Journal of Medicine. (Nankodo Co.,
Ltd., POBS272, Tokyo International 100-31, Japan) V.1-30, 1962-1991. For publisher information,
see IEDIEP. Volume(issue)/page;year 30,67,1991. EPA believes the RTECS LOAEL may be
incorrectly cited (should be 3.18 not 0.318). Both values suggest listing germanium.
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Germanium
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 108 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



4



0.40



2B



230



220



220



230
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.003
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for germanium diox de: Phosphors, transistors and diodes; electroplating (HSDB); naturally-occurr ng
Value





4,470

Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BST






Notes
assumed persistent; All use and env. fate data are for germanium dioxide; BST = biodegrades sometimes/reca citrant







-------
Halon 1011 (bromochloromethane)
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 109 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Halon 1011 (bromochloromethane)
2613
74975
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.01













Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect


ncreased liver-to-body weight ratio. Cloudy swelling
and vacuolization of hepatocytes.













Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 7
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.5
70

Y/N
Y/N
mg/L
ug/L
ug/L


2006









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For care nogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Halon 1011 (bromochloromethane)
    CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 110 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NGOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,881
22,974


65
106


0.5
0.461


0.05
0.0023


210
33.4


1
1


10
6


210
27.9

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasner, etal., 2006
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1/2, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,238
^Samples


Amount
Released



n
PWSs/Sites/Sa
mples


7
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0.165
% Samples with
detects


Number of
States



%
PWSs/Sites/Sam
pies with
detects
0.1
0.0
0.01
Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Not detected
Non-cancer: 7
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.45
Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects

Not detected
0.2
Median value of
Detects


0.422
90% of
Detects


0.45
99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1
Not detected
99% of
Detects

Not detected
Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Krasner, etal., 2006. Env. Sci. &Technol. 40 (23): pp. 7175-7185.




Fire extinguishing fluid; chemical intermediate (HSDB)
Value
15 days
23.7
1.41

0.00146
16,700
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
HCFC-22
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 111 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
HCFC-22
2654
75456
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











13.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1983




Critical Effect











Brain and Coverings - other degenerative changes,
Blood - changes in other cell count (unspecified),
Nutritional and Gross Metabolic - weight loss or
decreased weight gain




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1






1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



31.5

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/page/year 48(8),69,1983
Supplemental Data








Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   HCFC-22
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 112 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

2,972
7,075,769
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
35
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Refrigerant; low-temperature solvent; fluorocarbon resins, especially tetrafluoroethylene polymers (HSDB); gas
Value
15
35.04
1.08

4.07E-02
2,770
43
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly







-------
Hexane
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 113 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Hexane
4858
110543
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.06







1,429




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1989












Critical Effect



Decreased body weight gain







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1987






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

420

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
10 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis LOAEL = 570 mg/kg-d, UF = 10,000, oral rat study. Health and
Environmental Effects Document for n-Hexane, ECAO-CIN-Q076, Environmental Criteria and
Assessment Office, Final Draft, September 1989.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TIHEEC Toxicology and Industrial Health. (Princeton Scientific
Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year 1(3), 67,1985
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexane
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 114 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

14,489
39,844,882
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

38
53
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Naturally-occurring; solvent (NTP)
Value

149
3.9

1.8
9.5

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = biodegrades fast with acclimation







-------
Hydrazine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 115 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Hydrazine
6460
302012
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.001
3
3
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1

1999










Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.01
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










CACART; EPA; IARC; OEHHA; RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hydrazine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 116 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

5
165,485
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
16
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; rocket propellant; oxygen/chlorine scavenger (HSDB)
Value

14.3
-2.07

1.44E-08
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
Mestranol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 117 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Mestranol
2581
72333
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL (for ethinyl estradiol)
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.04

0.015
0.00083



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001

1981




Critical Effect











Hematalogical effects

Increased serum levels of alanineaminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GOT).




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.28

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
94 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.688
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, et al., 1981 as cited in Maier and Hermann, 2001 .
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)










CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
Mestranol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 118 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Mestranol
2581
72333
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL (for ethinyl estradiol)
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.04

0.015
0.00083



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001

1981




Critical Effect











Hematalogical effects

Increased serum levels of alanineaminotransferase
(ALT), aspartate aminotransferase (AST) and y-
glutamultransferase (GOT).




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.28

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
94 Li
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.688
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data; Maier and Hermann, 2001 . Regulatory Toxicology and Pharmacology, 34, pp 53-61 .
Lowest Observed Adverse Effect Level
Supplemental Data; Tennant, et al., 1981 as cited in Maier and Hermann, 2001 .
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)










CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Mestranol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 119 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin.etal., 2002

HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples
70





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States


%
PWSs/Sites/Sam
pies with
detects
4.3





Units
States
States
States
Minimum value of
Detects


Non-cancer: 0.688
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
0.407













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.017

90% of
Detects


Units for Mag
data
ug/L
Notes
Response to Comment on National Surface Water Reconnaissance
Kolpin et al., 2002: Env. Sci. & Technol, 36(18), pp. 4007-4008.

Cancer:







Metabolite of ethinyl estradiol
Value
60

4.68


Practically
insoluble
9
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
   Methamidophos
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 120 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
965,584





Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
39





Units
States
States
States



Year
1997











Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 6.9 ug/L
Ground water chronic: 3.8 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.304
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







nsecticide (HSDB)
Value

3.848
-0.8

8.70E-10
1000000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = Biodegrades Slowly







-------
Methanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 121 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methanol
2508
67561
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.5

0.5







3.13



5,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect

ncreased SAP & SGPT& liver weight, decreased brain
weight









Liver - other changes



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3,500

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude , „ ,
10 10 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. EPA, 1986; Basis = NOEL 500 mg(kg-d; UF = 1,000; Rat
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 200 day oral study in rats; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,89,1994
Supplemental Data


Rats; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,87,1984








UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methanol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 122 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

10,966,234
201,697,278
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

41
52
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; gasoline additive (HSDB); anti-freeze
Value

1
-0.77

4.56E-06
1000000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades Fast







-------
Methyl bromide (Bromomethane)
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 123 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methyl bromide (Bromomethane
2601
74839
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0014
0.001
0.0014
0.003
1





29.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988
2006

9/1992
1966










Critical Effect

Epithelial hyperplasia in theforestomach


Gastro






Kidney, Ureter, Bladder - other changes in urine
composition, Skin and Appendages - hair, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1





1989
1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
0.05
9.8

Y/N
Y/N
mg/L
ug/L
ug/L


2006



Developmental



Prevalence Magnitude , „
67 L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.891
Notes
Reference Dose
Reference Dose; Basis = NOAEL 1 .4 mg/kg-day; UF = 1 ,000; Rat. Danse et al.r 1984
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; FCTOD7 Food and Chemical Toxicology.
(Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year28,109,1990
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl bromide (Bromomethane)
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 124 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

20,198
23,328


155
175


0.77
0.75


0.07
0.09


43
38.1


1
1.6


11
8.1


34
27.2

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,317



Amount
Released
32,803,943
200
533,748
# PWSs/Sites
sampled

3



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0.069



Number of
States
29
3
17
% PWSs/Sites
with detects

0.04



Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.891
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.5



Year
1997
2004
2004
Maximum
value of
Detects

0.1



0.5



0.5



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled fumigant (NTP); gas
Value
20-26.7
9-22
1.19

7.34E-03
13,400
42
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BS






Notes
hydrolysis only; BS = biodegrades slowly







-------
Methyl tert-butyl ether
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 125 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methyl tert-butyl ether
11918
1634044
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value




0.3


0.01



300




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




8/1996


1991








Critical Effect




Hepatic: Decreased blood urea nitrogen levels.






Kidney, Ureter, Bladder - changes in bladder weight, Blood
- changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - changes in
calcium




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


0.0018

3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1






1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


2,100
19.4
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „
58 L'
HRL Ratio(s)
NC HRL/UCMR 90%: 58.3
CAR HRL/UCMR 90%: 0.539
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis NOAEL 100 mg/kg-d
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in rat; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 9(5), 525, 1990
Supplemental Data










OEHHA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl tert-butyl ether
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 126 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,617



17



0.47



5



49



9.2



36



49



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,328


Amount
Released

40,177
2,040,906
# PWSs/Sites
sampled

424


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

9.8


Number of
States

17
42
% PWSs/Sites
with detects

0.01


Units
States
States
States
Minimum value of
Detects

Non-cancer: 58.3
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002



2,300


Year

2004
2004
Maximum
value of
Detects

0.3


7.85


1,800


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 0.539



Notes





Octane booster in gasoline; manufacture of isobutene; extraction solvent (HSDB)
Value
15
6
0.94

5.87E-04
51,000
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly







-------
Metolachlor
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 127 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor
35270
51218452
Attribute Scores
Potency Severity
4 3
Prevalence Magnitude
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1
0.15
0.1
0.15







25



1,150
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1995
1988
2006













Critical Effect
Decreased body weight gain
Decreased body weight gain









Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - phosphatases



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



C

mg/L
(mg/kg-d)"1
(mg/kg-d)-1





1988






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


3.5
700

Y/N
Y/N
mg/L
ug/L
ug/L


2006








3-model Categorical Prediction
NL?
HRL Ratio(s)
NC HRL/NCOD R2 90%: 321
Notes
Reference Dose; Basis NOAEL = 9.7 mg/kg-d; UF = 100. OPP RED.
Reference Dose; Basis = NOEL 15 mg/kg-d; UF = 100. Ciba-Geigy, 1983
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 14,103,1989
Supplemental Data


NNGADV Nippon Noyaku Gakka shi. Journal of the Pesticide Science Society of Japan. (Nippon
Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
Volume(issue)/page/year 14,103,1989




Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 ~6 cancer risk was used.

-------
   Metolachlor
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 128 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


13,007



116



0.89



0.01



13.8



0.57



2.18



7.1

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
PPMP ambient water
PPMP finished water

CAL DHS
STORE!
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,165



Amount
Released
67,336,211


n
PWSs/Sites/Sa
mples
203
582


n
PWSs/Sites/Sa
mples
7,345
2,082
1,817



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
102
233
288
198
#with Detects
15
676
25.4
8.76
1.23

Number of
States
48


%
PWSs/Sites/Sam
pies with
detects
50.2
40
89.2
86.8
%
PWSs/Sites/Sam
pies with
detects
0.2
32.5
0.0002



Units
States
States
States
Minimum value of
Detects
0.01
0.005


Minimum value of
Detects
0.05
0.00867
Non-cancer: 321
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



77.6



Year
1997


Maximum
value of
Detects
0.079
0.226
3.32
0.661
Maximum
value of
Detects
0.7
86
0.025
0.12
0.125

0.58



6.71



Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes



Median value of
Detects




Median value of
Detects
0.06
0.19
95% of
Detects


0.033
0.336
90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2001
2002
Pesticide Pilot Mentoring Program (USGS/EPA)

Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Herbicide (HSDB)
Value
47;78
22-310
3.13

9.00E-09
530
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
aerobic;anaerobic; BSA = biodegrades slow with acclimaton







-------
Metolachlor ESA
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 129 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor ethanesulfonic acid (ESA)
79218
171118095
Attribute Scores
Potency Severity
2 1
Prevalence Magnitude
6 6
Scores based on parent
HEALTH EFFECTS DATA1 - See Metolachlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










21000





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










No biologically significant effects





Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



>7,000

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : >3,210 (NAWQA data for metolachlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR METOLACHLOR ESA
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
     Metolachlor ESA
     CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 130 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value
of Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag No(es
data
Finished Water Occurrence Data - FOR METOLACHLOR PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


13,007



116



0.89



0.01



13.8



0.57



2.18



7.1

Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
FOR METOLACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NCOD R290%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples
83
318
n
PWSs/Sites/Sa
mples
7,345
2,082



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
19
198
#with Detects
15
676



Number of States



%
PWSs/Sites/Samp
les with detects
22.9
51.9
%
PWSs/Sites/Samp
les with detects
0.2
32.5



Units
States
States
States
Minimum value
of Detects
0.50
0.02
Minimum value
of Detects
0.05
0.00867
Non-cancer: >3,210
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
2.21
2.24
Maximum
value of
Detects
0.7
86









ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes



Median value of
Detects


Median value of
Detects
0.06
0.19
95% of
Detects


90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2001 - FOR METOLACHLOR ESA
2002 - FOR METOLACHLOR ESA
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.as
px

NCOD data for metolachlor - parent



Pesticide degradate
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation Code







Notes








-------
Metolachlor OA
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 131 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Metolachlor oxani ic acid (OA)
79220
152019733
Attribute Scores
Potency Severity
2 1
Prevalence Magnitude
6 6
Scores based on parent
HEALTH EFFECTS DATA1 - See Metolachlor Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










1,000





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










No biologically significant effects





Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7,000

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
NL
HRL Ratio(s)
HRL/NAWQA 90% : 3,210 (NAWQA data for metolachlor
parent)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; EPA OPP NOAEL - FOR METOLACHLOR OA
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
     Metolachlor OA
     CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 132 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag No(es
data
Finished Water Occurrence Data - FOR METOLACHLOR PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


13,007



116



0.89



0.01



13.8



0.57



2.18



7.1

Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
FOR METOLACHLOR - PARENT
CAL DHS
STORE!
HRL Ratios (HRL/NCOD R290%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KQC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples
138
404
n
PWSs/Sites/Sa
mples
7,345
2,082




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
14
152
#with Detects
15
676




Number of
States


%
PWSs/Sites/Sam
pies with
detects
10.1
37.6
%
PWSs/Sites/Sam
pies with
detects
0.2
32.47




Units
States
States
States
Minimum value of
Detects
0.50
0.02
Minimum value of
Detects
0.05
0.00867
Non-cancer: 3,210
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
4.42
1.41
Maximum
value of
Detects
0.7
86












ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes


Median value of
Detects


Median value of
Detects
0.06
0.19
95% of
Detects


90% of
Detects
0.1
1.4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2001 - FOR METOLACHLOR OA
2002 - FOR METOLACHLOR OA
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminants.
aspx

NCOD data for metolachlor - parent



Pesticide degradate
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Microcystin-LR
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 133 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Microcystin-LR
76859
101043372
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.000003







Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date








2006







Critical Effect








Liver effects







Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.021

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 4
Scores based on supplemental data HRL Ratio(s)
NC HRL/AWWARF Typical Range MAX: 0.21
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data - draft RfD; Basis NOAEL 3 ug/kg-d. Ueno, Y., Y. Makita, S. Nagata et al. 1 999.
No chronic oral toxicity of a low-dose of microcystin-LR, a cyanobacterial hepatoxin, in female
Balb/C mice. Environ. Toxicol. 14(1):45-55.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Microcystin-LR
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 134 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
US and Canadian drinking water (bloom
area, source, finished water)
US and Canadian drinking water (bloom
area, source, finished water)
HRL Ratios (HRL/AWWARF Typical Range
MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released



n
PWSs/Sites/Sa
mples
677
677





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
542
542





Number of
States



%
PWSs/Sites/Sam
pies with
detects
80
80





Units
States
States
States
Minimum value of
Detects

0.002
Non-cancer: 0.21
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year



Maximum
value of
Detects
0.1
1,200















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


99% of
Detects


Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Maximum of typical range of detects (AWWARF, Carmichael)
Maximum and m numum of detects (AWWARF, Carmichael)




Cyanobacterial toxin
Value







Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Molinate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 135 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Molinate
12912
2212671
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.002

0.002







13.1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2001
1988














Critical Effect
Degeneration/demyelination in sciatic nerve and
atrophy/reserve cell hyperplasia of muscle
Reproductive toxicity. Alteration in sperm morphology,
reduced number of viable fetuses/litter, increased
number of resorptions/litter









Endocrine - other changes, Blood - normocytic anemia,
Nutritional and Gross Metabolic - body temperature
decrease




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „
1 8 L'
HRL Ratio(s)
NCHRL/UCMR90%: 2.46
Notes
Reference Dose; Basis LOAEL = 0.3 mg/kg-d, UF = 300, 2-year rat study. A Determination of the
Existence of a Common Mechanism of Toxicity and a Screening Level Cumulative Food Risk
Assessment, December 2001. OPP issued RfD as part of health assessment not the RED;
http://epa.gov/oppsrrd1/cumulative/thiocarb.pdf
Reference Dose; Basis NOEL 0.2 mg/kg-d; UF = 100. Stauffer Chemical Co., 1981
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 43 week study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(1 0) , 1 04, 1 975
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Molinate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 136 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621


1


0.03


5.7


5.7


5.7


5.7


5.7


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118



Amount
Released
3,669,398
115
2,089
n
PWSs/Sites/Sa
mples

120



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
1.68



Number of
States
6
1
2
%
PWSs/Sites/Sam
pies with
detects
0.3
0.001



Units
States
States
States
Minimum value of
Detects


Non-cancer: 2.46
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



200



Year
1997
2004
2004
Maximum
value of
Detects
0.004
0.0372



3.41



47.9



Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects

95% of
Detects

Units
ug/L

Cancer:



Notes
Pesticide Pilot Mentoring Program (USGS/EPA)





Herbicide (HSDB)
Value
40-160
80-120
3.21

4.10E-06
970
19
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BST






Notes
BST = biodegrades sometimes/recalcitrant







-------
Molybdenum
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 137 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Molybdenum
18825
7439987
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.005
0.005
0.005




0.03


0.5




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1992
2006













Critical Effect

increased uric acid levels






Effects on repro & fetal development (decreased
gestational weight ga n, prolonged estrus cycle, failure to
breed). Renal failure, diuresis, proteinuria


Liver - other changes, Kidney, Ureter, Bladder - other
changes, Nutritional and Gross Metabolic - weight loss or
decreased weight ga n




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1993






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
0.2
35

Y/N
Y/N
mg/L
ug/L
ug/L


2006



Teratogen List



Prevalence Magnitude
98 Li
HRL Ratio(s)
NCHRL/NIRS90%: 1.17
Notes
Reference Dose
Reference Dose; Koval'skiy et al.( 1961; oral study in humans; UF = 30; Basis LOAEL = 0.14 mg/kd-
d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; UL; IOM
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 9 week oral study in rabbits; VCVN5 "Vrednie chemichescie
veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic
substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.
Volume(issue)/page/year -, 317, 1989
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.



UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Molybdenum
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 138 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


989


77


7.79


6.1


180


10


30


110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released


# PWSs/Sites
sampled



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



Number of
States


% PWSs/Sites
with detects



Units
States
States
States
Minimum value of
Detects

Non-cancer: 1.17
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year


Maximum
value of
Detects







Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data for molybdenum trioxide: As steel alloy; chemical reagent (HSDB); naturally-occurring
Value





1,066

Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BST






Notes
assumed persistent; All use and env. fate data for molybdenum trioxide; BST = biodegrades sometimes/reca citrant




All use and env. fate data for molybdenum trioxide


-------
Nitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 139 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nitrobenzene
3998
98953
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002

0.0005












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2009














Critical Effect

Increased reticulocytesand methemaglobinemia














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1990
1996





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

14

Y/N
Y/N

ug/L
ug/L






Teratogen List



Prevalence Magnitude
1 10 NLi
HRL Ratio(s)
NCHRL/UCMRAM90%: 0.14
Notes
Reference Dose
Reference Dose; NTP, 1983; subchronic rat study; UF = 1,000; Basis BMDL = 1.8 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.


CACART, IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Nitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 140 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,064


2


0.065


21. 6


100


60.8


100


100


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
UCMR finished water

HRL Ratios (HRL/UCMR AM 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released

60
350,301
# PWSs/Sites
sampled
338





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0





Number of
States

1
14
% PWSs/Sites
with detects
0





Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer: 0.14
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year

2004
2004
Maximum
value of
Detects
Not Detected















Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes

Analyzed under UCMR 1 , List 1 , Assessment
Monitoring with detection limit of 10 ug/L.





National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
Not Detected

Cancer:



Notes
Analyzed under UCMR 1, List 2, Screening Survey with detection limit of
0.5 ug/L.





Solvent (NTP)
Value
15
30.6-370
1.85

2.40E-05
1,800
31
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = biodegrades slowly







-------
Nitroglycerin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 141 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitroglycerin
2252
55630
Attribute Scores
Potency Severity
7 6
Prevalence Magnitude
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.125
0.008


105
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Cardiac - cardiomyopathy including infarction, Cardiac
- EKG changes not diagnostic of specified effects,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - multiple enzyme effects



Behavioral - somnolence (general depressed activity)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.2




mg/L
(mg/kg-d)-1
(mg/kg-d)-1


1987









Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.292
2
Y/N
Y/N

ug/L
ug/L






Teratogen




3-model Categorical Prediction
L?-L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week oral study in rats; FATOAO Farmakologiya i
Toksikologiya (Moscow), For English translation, see PHTXA6 and RPTOAN. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year
48,76,1985
Supplemental Data; RTECS LOAEL, acute human study


Oral study in rats; YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan
K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year 13,3649,1985







EPA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Nitroglycerin
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 142 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released

0.2
55,979
# PWSs/Sites
sampled





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States

1
9
% PWSs/Sites
with detects





Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year

2004
2004
Maximum
value of
Detects













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pharmaceutical/medication; production of explosives; Rocket propellants; (HSDB)
Value


1.62

9.87E-08
1,380
32
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades Fast







-------
N-Methyl-2-pyrrolidone
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 143 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Methyl-2-pyrrolidone
9980
872504
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.6


120



3,914
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date








2001







Critical Effect








Decreased weight gain, neurobehavioral effects,
sedative effects


Endocrine - changes in spleen weight



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

4,200

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
10 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Tolerable Daily Intake; Basis NOAEL = 169 mg/kg-d, UF = 300, 90-day rat study, WHO/UNEP CICAD
TDI Study #35
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientif c & Technical Information. Volume(issue)/page/year
OTS0528073
Supplemental Data


ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(ssue)/page/year 26,1581,1976








UMD; CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   N-Methyl-2-pyrrolidone
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 144 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

17,972
6,311,503
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

13
42
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical industry solvent; solvent for pesticide appl cation for food packing materials (HSDB)
Value


-0.38

3.20E-09
1,000,000
42
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades Fast







-------
N-Nitrosodiethylamine (NDEA)
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 145 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodiethylamine (NDEA)
2243
55185
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.00002
150
36
B2
2A
mg/L
(mg/kg-d)-1
(mg/kg-d)"1






1987





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.0002
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
1 2 Li
HRL Ratio(s)
See also supplemental water data No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data










CACART; EPA; OEHHA; IARC; RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitrosodiethylamine (NDEA)
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 146 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released

0
1,000
n
PWSs/Sites/Sa
mples
26
26


Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0
0


Number of
States

0
1
%
PWSs/Sites/Sam
pies with
detects
0
0


Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Non-cancer:
Amount Range


Gasoline and lubr
Value
38
142.7
0.48

3.63E-06
106,000
53
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year

2004
2004
Maximum
value of
Detects
Not Detected
Not Detected






Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
Not Detected
90% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





cant additive; antioxidant; stabilizer n plastics (HSDB); Disinfection by-Product
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS/BSA






Notes
BS = Biodegrades Slowly; BSA = Biodegrades Slowly with Acclimation







-------
N-Nitrosodimethylamine (NDMA)
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 147 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodimethylamine (NDMA)
2446
62759
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.000008







0.2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











mmunological Includ ng Allergic - decrease in cellular
immune response, Immunological Including Allergic -
decrease in humoral mmune response, Related to Chronic
Data - death




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.00007
51
16
B2
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1





1986
1987



Liver

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.056
0.00069
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude , „ ,
10 2 L' L
Scores based on supplemental data HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.329
CAR HRL/CAL DHS 90%: 0.004
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JTEHD6 Journal of Toxicology and Environmental Health.
(Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year 37,351 ,1992
Supplemental Data




IRIS



(Vol. 17, Suppl. 7; 1987)

CACART; RAIS; EPA; OEHHA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitrosodimethylamine (NDMA)
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 148 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



n
PWSs/Sites/Sa
mples
409
585




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
87
0




Number of
States



%
PWSs/Sites/Sam
pies with
detects
21.3
0




Units
States
States
States
Minimum value of
Detects
0.001
Not Detected
Non-cancer: 0.329
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects
440
Not Detected












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.009
Not Detected
90% of
Detects
0.17
Not Detected
Units for Mag
data
ug/L
ug/L
Cancer: 0.004



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwaterfPages/Chemicalconta
minants.aspx





ndustrial solvent; antioxidant; formerly in the production of rocket fuel (HSDB); Disinfection by-Product
Value
38
12
-0.57

1.82E-06
Soluble
52
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation



@37°C



-------
N-Nitroso-di-n-propylamine NDPA
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 149 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-di-n-propylamine (NDPA)
8798
621647
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0005
7
7
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1987
1987



Liver

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.005
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude .,, „
2 2 NL.-L,
HRL Ratio(s)
See also supplemental water data CAR HRL/STORET 90% : 0.00049
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data




IRIS





CACART; EPA; RAIS; OEHHA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitroso-di-n-propylamine NDPA
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 150 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
STORE!
HRL Ratios (HRL/STORET 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

0
506
n
PWSs/Sites/Sa
mples
127
1,309



Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
0
22



Number of
States

0
2
%
PWSs/Sites/Sam
pies with
detects
0
1.68



Units
States
States
States
Minimum value of
Detects
Not Detected
0.19
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects
Not Detected
20









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
10
90% of
Detects
Not Detected
10.24
Units
ug/L
ug/L
Cancer: 0.00049



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Research chemical (HSDB); Disinfection by-Product?
Value
38
130
1.36

5.38E-06
10,000
44
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation



@37°C



-------
N-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 151 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Nitrosodiphenylamine
3193
86306
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.02







20.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1966




Critical Effect



Corneal opacities, epithelial hyperplasia of the bladder
and decreased weight gain







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude ,,,
2 1 NL
HRL Ratio(s)
NC HRL/CAL DHS 90% : 1 .84
See also supplemental water data CAR HRL/CA|_ DH£. g()% . Q Og32
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NC1 1979; Basis LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 17-week oral study in rabbit; GTPZAB Gigiena Truda i
Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/paae/vear 10(4). 60.1 966
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.0049
0.009

B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1987







IRIS


Cited by OEHHA
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


140
7.1
Y/N
Y/N

ug/L
ug/L










CACART; EPA; OEHHA; RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   N-Nitrosodiphenylamine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 152 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
14
n
PWSs/Sites/Sa
mples
133



#with Detects

Units
Ibs/yr
Ibs/yr
Ibsfyr
#with Detects
1



% Samples with
detects

Number of
States

0
2
%
PWSs/Sites/Sam
pies with
detects
0.75



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
76.2

Non-cancer: 1.84
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
76.2



Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
76.2
90% of
Detects
76.2
Units for Mag
data
ug/L

Cancer: 0.0932



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Rubber and polymer additive; chemical reagent (HSDB); DBP
Value

6,154
3.13

1.21E-06
35

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
N-Nitrosopyrrolidine (NPYR)
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 153 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosopyrrolidine (NPYR)
10160
930552
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude

HEALTH EFFECTS DATA1 See also supplemental water data
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.002
2.1
2.1
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1986
1987



Liver

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.02
Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction

HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data




IRIS





CACART; EPA; OEHHA; RAIS; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitrosopyrrolidine (NPYR)
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 154 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released


n
PWSs/Sites/Sa
mples
27





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0





Number of
States


%
PWSs/Sites/Sam
pies with
detects
0





Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year


Maximum
value of
Detects
Not Detected















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes


Cancer:







Research chemical (HSDB)
Value
38
19
-0.19

4.89E-08
1,000,000
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation



@37°C



-------
Norethindrone (19-Norethisteron
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 155 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Norethindrone (19-Norethisterone)
2525
68224
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













0.0167



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Critical Effect













The norethindrone abel indicates that if the drug is
taken during the first trimester of pregnancy that the
riskfor hypospadia in male offspring doubles.



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
NTP Carcinogen Classification




Reasonably antic
carcinogenic
mg/L
(mg/kg-d)-1
(mg/kg-d)-1

Dated to be










Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.04

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 4
HRL Ratio(s)
NC HRL/Kolpin MAX: 0.0459
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Daily Dose (MRDD)








NTP 1 1th Report on Carcinogens; no quantificatio of dose-response

CACART
UMD, CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Norethindrone (19-Norethisteron
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 156 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, et al., 2002

HRL Ratios (HRL/Kolpin MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released


n
PWSs/Sites/Sa
mples
70



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States


%
PWSs/Sites/Sam
pies with
detects
12.8



Units
States
States
States
Minimum value of
Detects


Non-cancer: 0.0459
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year


Maximum
value of
Detects
0.872







Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.048

90% of
Detects


Units for Mag
data
ug/L
Notes
National Surface Water Reconnaissance; Kolpin, etal., 2002. Env.
Sci.&Technol., 36(6), pp. 1202-1211.

Cancer:








Value
60

2.97

5.80E-10
7.04
12
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
n-Propylbenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 157 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
n-Propylbenzene
4328
103651
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











2.5



6,040
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood - changes in spleen



Behavioral - somnolence (general depressed activity)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



5.83

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
4 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 1.21
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVQH "Vrednie chemichescie veshestva,
galogenproisvodnie uglevodorodov". (Hazardous substances Qalogenated hydrocarbons)
Bandman A.L. et al., Chimia, 1990. Volume(issue)/page/year -,167,1990; 24 week oral study in rat
Supplemental Data


Rats; FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher
information, see FCTOD7. Volume(issue)/page/year 2,327,1964









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   n-Propylbenzene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 158 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,724
22,970


42
54


0.33
0.24


0.03
0.1


34
21


0.7
0.6


4.8
4


34
21

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309


Amount
Released



# PWSs/Sites
sampled

53


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

1.23


Number of
States



% PWSs/Sites
with detects

0.004


Units
States
States
States
Minimum value of
Detects

Non-cancer: 1.21
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002



47


Year



Maximum
value of
Detects

0.024


5


47


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Manufacture of methylstyrene; text le dyeing; printing solvent; asphalt and naphtha constituent (HSDB)
Value
15
495-955
3.69

1.05E-02
23.4
22
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly







-------
o-Toluidine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 159 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
o-Toluidine
3768
95534
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











340




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Kidney, Ureter, Bladder - proteinuria, Blood - normocytic
anemia, Nutritional and Gross Metabol c - weight loss or
decreased weight ga n.




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.24
0.18

2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1

2000










Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

793
0.194
Y/N
Y/N

ug/L
ug/L






Teratogen list



Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VINIT Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii
(VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) Use information
broker to obtain publications. Vo ume(issue)/page
Supplemental Data





HEAST


Vol. 77; 2000

IARC, RAIS, OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   o-Toluidine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 160 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

5
10,774
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
9
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Intermediate in the manufacture of dyes, rubber, Pharmaceuticals and pesticides (HSDB)
Value

74.04
1.32

1.98E-06
16,600

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
Oxirane, methyl-
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 161 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxirane, methyl-
2661
75569
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001










26




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1981















Critical Effect
ncreased combined incidence of hyperkeratosis,
hyperplasia and papillomas.










Brain and Coverings - other degeneratve changes, Liver -
other changes, Blood - other changes




Cancer Data
EPA Lifetime Cancer Risk, 10"*
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.15
0.24
0.24
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1
1990






1994






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

60.7
0.233
Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose; Basis = BMDL „ 1 .4 mg/kg-d; UF = 1 000.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 45-day study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(7), 76,1 981
Supplemental Data











CACART; RAIS; OEHHA; EPA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Oxirane, methyl-
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 162 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

28,761
433,536
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

5
28
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (NTP)
Value

2.324
0.03

6.98E-05
590,000
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BS






Notes
PBT; BS = biodegrades slow







-------
Oxydemeton-methyl
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 163 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxydemeton-methyl
6458
301122
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00013




0.0025









10
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1967










Critical Effect
Decreased erythrocyte & brain ChE




Decreased body weight









Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.91

Y/N
Y/N

ug/L
ug/L






male, female



Prevalence Magnitude
95 Li
HRL Ratio(s)
NC HRL/SWC EEC: 1.01
Notes
Reference Dose; Basis = NOAEL 0.013 mgfkg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


85JDAH "Organophosphorus Pesticides Organic and Biological Chemistry," Eto, M., Cleveland, OH, CRC
Press, Inc., 1974 Volume(issue)/page/year -,197,1974








CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Oxydemeton-methyl
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 164 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
154,227
0
0
n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
19
0
0
%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year
1997
2004
2004
Maximum
value of
Detects


Surface water chronic: 0.9 ug/L









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects


Units
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic: 0.006 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1.01
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







nsecticide (HSDB)
Value


-0.74

1.62E-13
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS =Biodegrades Slowly







-------
Oxyfluorfen
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 165 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Oxyfluorfen
34731
42874033
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.003

0.003











5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986














Critical Effect

ncr. abs. liver weight; nonneoplastic lesions













Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0732


C

mg/L
(mg/kg-d)-'
(mg/kg-d)-1
(mg/kg-d)-1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


21
0.478
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 6 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 3.0
CAR HRL/SWC EEC: 0.067
Notes
Reference Dose
Reference Dose; Basis = NOEL 0.3 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,643,1991








EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Oxyfluorfen
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 166 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
705,255
0
5
n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
37
0
2
%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 7.1 ug/L
Non-cancer: 3.0
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic: 0.08 ug/L
Cancer: 0.067







Pesticide; herbicide
Value

46,800
4.73

8.23E-07
0.116
5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = biodegrades sometimes/recalcitrant; PBT







-------
Perchlorate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 167 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perchlorate
24310
14797730
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0007






6







Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

ug/L
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2005






2000







Critical Effect

Radioactive iodide uptake inhibition (RAIU) in the
thyroid






Decreased newborn TSH







Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



See notes

mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-lnterimHA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
15
4.9

Y/N
Y/N
ug/L
ug/L
ug/L






Teratogen



Prevalence Magnitude .,, „
9 8 NL!'L!
HRL Ratio(s)
NCHRL/UCMR90%: 0.35
Notes
Reference Dose
Reference Dose; Basis NOEL 0.007mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Brechner et al. 2000
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Not likely to pose a risk of thyroid cancer in humans, at least at doses below those necessary to alter
thyroid hormone homeostasis, based on the hormonally-mediated mode of action in rodent studies and
species differences in thyroid function (IRIS).



UMD
Interim Health Advisory; EPA is revisiting the intermin hHealth Advisory for perchlorate.
The HRL for the CCL differs from the Interim HA based on the RSC used in the health advisory (0.62)
and the default RSC (0.2) used for the CCL process.

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Perchlorate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 168 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,554



147



4.14



4



420



6.5



14



59



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.35
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Smokeless rocket and jet propellant; explosives; analytical chemistry, etch ng and engraving agent (HSDB)
Value





200,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes





All use and env. fate data are for ammonium perchlorate.


-------
Perfluorooctane sulfonic acid
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 169 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perfluorooctane sulfonic acid (PFOS)
12176
1763231
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
EPA/FR NOAEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










0.1
0.03


251


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Critical Effect










Reduced F2 Body Weight
Decreased body weights, increased liver weights,
lowered serum total cholesterol, lowered
triiodothyronine (T3) concentration, and lowered
estradiol levels





Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-Provisional HA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.2
0.2

Y/N
Y/N
ug/L
ug/L
ug/L


January 2008







Prevalence Magnitude , „ ,
10 7 L' L
HRL Ratio(s)
NC HRL/MN MW MAX: 0.143
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
No Observed Adverse Effect Level in 2 generation reproductive study in rats. Supplemental Data - FR
October 18, 2000 (Volume 65, Number 202)] Perfluorooctyl Sulfonates; Proposed Significant New Use
Rule [Page 6231 9-62333]
Supplemental Data - Seacat et al., 2002, Toxicol. Sci. 68, 249-264. EPA Provisional HA:
http://www.epa.gOV/waterscience/criteria/d rinkinglpha-PFOA_PFOS.pdf
Lowest Observed Adverse Effect Level













Provisional Health Advisory: http://www.epa. gov/waterscience/criteria/drinking/pha-PFOA_PFOS.pdf
Note: HRL is based on adult exposure factors (70 kg body weight and 2 L/d ingestion). The HRL was
calculated in a d fferent manner than EPA's provisional HA because child exposure factors and
toxicokinetic adjustments were used to derive the provisional HA.

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Perfluorooctane sulfonic acid
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 170 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Select New Jersey Water Systems
Select Minnesota municipal wells
Select Minnesota non-community wells
Select Minnesota private wells
Aggregate of above Minnesota wells
HRL Ratios (HRL/MN MW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released


n
PWSs/Sites/Sa
mples
23
37
22
26
85



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
13
6
0
0
6



Number of
States


%
PWSs/Sites/Sam
pies with
detects
57%
16.2%
0%
0%
7.1%



Units
States
States
States
Range of Detects
(ug/L)
0.0042-0.019
ND-1.4
ND
ND
ND-1.4
Non-cancer: 0.143
Amount Range
10-500K
0
Units
Ibs/yr
Ibs/yr
Year
2002
2003 (EPA est.)





Year





Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Notes
Targeted Sampl ng 2006 - Targeted study "Determination of Perfluorooctanoic Acid (PFOA) in Aqueous Samples, Final Report." Jan 2007,
NJDEP, Division of Water Supply.
Targeted Sampling 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Cancer:





Estimate of zero as phased out.
Surface-active agents in aqueous media; chemical intermediate; in fire-fight ng applications, floor polish; metal plating baths; pest c de active ingred ent for ant bait traps. (HSDB)
Value

100,000



370

Units
length of time
L/kg
unitless
cm3/g
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = biodegrades sometimes/recalcitrant







-------
Perfluorooctanoic acid (PFOA)
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 171 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Perfluorooctanoic acid (PFOA)
6614
335671
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












0.46



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












2006



Critical Effect












Increased maternal liver weight at term



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-Provisional HA
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.4
1.1

Y/N
Y/N
ug/L
ug/L
ug/L


January 2008







Prevalence Magnitude
10 6
Scores based on supplemental data HRL Ratio(s)
NC HRL/MN MW MAX: 1.22
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data (BMDL10), Lau, 2006. Tox. Sci., 90, 2, pp. 510-518. EPA Provisional HA:
http://www.epa.goV/waterscience/criteria/d rinking/pha-PFOA_PFOS.pdf












Provisional Health Advisory: http://www.epa. gov/waterscience/criteria/drinking/pha-PFOA_PFOS.pdf
Note: HRL is based on adult exposure factors (70 kg body weight and 2 L/d ingestion). This value differs
from EPA's provisional HA because child exposure factors and toxicokinetic adjustments were used to
derive the provisional HA.

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Perfluorooctanoic acid (PFOA)
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 172 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


















Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
NJDEP - Jan 2007
Little Hocking, OH Municipal Wells (FW)
Select Minnesota municipal wells
Select Minnesota non-community wells
Select Minnesota private wells
Aggregate of above Minnesota wells
HRL Ratios (HRL/MN MW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



n
PWSs/Sites/Sa
mples
23
No data
37
22
26
85




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
18

6
0
1
7




Number of
States



%
PWSs/Sites/Sam
pies with
detects
78

16.2%
0%
3.8%
8.2%




Units
States
States
States
Range of Detects
(ug/L)
<0.004 - 0.039
1.5-7.2
ND-0.9
ND
ND-0.67
ND-0.9
Non-cancer: 1.22
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year







Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Notes
Targeted study ' Determination of Perfluorooctanoic Ac d (PFOA) in Aqueous Samples, Final Report." Jan 2007, NJDEP, Division of Water
Supply.
Emmett, et al., 2006. J. Occ. Env. Med. Little Hocking, OH; data from 2002-2005.
Targeted Sampling 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Targeted Sampl ng 2004-2005 - H. Goeden and J. Kelly. Perfluorochemicals in Minnesota, MN DOH, 2/27/06.
Cancer:







Production of fluoropolymers (e.g., Teflon) and fluoroelastomers; in fire-fight ng applications, cosmetics, greases and lubricants, pa nts, polishes and adhesives (HSDB)
Value
180
27,000


9.10E-02

1
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
PBT; BST = biodegrades sometimes/recalcitrant







-------
Permethrin
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 173 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Permethrin
35815
52645531
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.25
0.05

0.05
0.2
0.05










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986



1999










Critical Effect
Neurotox (aggression, abnormal/ decreased movement),
increased body temperature. Q1* 0.0096 (mg/kg/day)-1.
See CAR
ncreased liver weight


Neurol.











Cancer Data
EPA Lifetime Cancer Risk, 10"*
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0096



3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1991






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


1,750
3.65
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 7 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 1,944
CAR HRL/SWC EEC: 4.05
Notes
Reference Dose; Basis = NOAEL 25 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 5 mg/kd-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level; ATSDR MRL-int.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Permethrin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 174 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total




Amount
Released
1,066,056
0
17,979




Units
Ibsfyr
Ibs/yr
Ibs/yr




Number of
States
48
0
7




Units
States
States
States




Year
1997
2004
2004












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 0.9 ug/L
Ground water chronic: 0 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 1,944
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 4.05







nsecticide (HSDB)
Value

178,000
6.5

1.87E-06
0.006

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF/BST






Notes
BF = biodegrades fast; BST = biodegrades sometimes/reca c trant







-------
Profenofos
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 175 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Profenofos
34318
41198087
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005




0.0004





0.05



162
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1990










Critical Effect
Inhibition of plasma & RBC ChE activity










Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase



Behavioral - somnolence (general depressed activity),
Behavioral - tremor, Gastrointestinal - changes in structure
or function of salivary glands
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
86 Li
HRL Ratio(s)
NC HRL/SWC EEC: 3.5
Notes
Reference Dose; Basis = NOEL 0.005 mg*g-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 12,781,1987
Supplemental Data


TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 73,16,1984









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Profenofos
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 176 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
879,776
0
255
n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
14
0
1
%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 0.1 ug/L
Non-cancer: 3.5
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic: 0.03 ug/L
Cancer:







Pesticide, insecticide, acaricide (HSDB)
Value


4.68

2.21 E-08
28
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = biodegrades sometimes/recalcitrant; PBT







-------
Quinoline
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 177 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quinoline
3467
91225
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.001
3

B2

mg/L
(mg/kg-d)-1
(mg/kg-d)"1


2001


2001






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.01
Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
L?-L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data




IRIS
IRIS

Hirao et al., 1976; oral study in rats


CACART, EPA, RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Quinoline
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 178 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

62
28,629
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
8
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year

2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; pharmaceutical (anti-malarial); flavoring (HSDB)
Value

1,837
2.03

1.67E-06
6,110

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades Fast with Acclimation







-------
RDX
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 179 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
RDX
5404
121824
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.003
0.003
0.003
0.03






40




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988
2006

6/1995











Critical Effect

nflammation of the prostate.









Cardiac - other changes, Blood - pigmented or nucleated
red blood cells, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases




Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.03
0.11

c

mg/L
(mg/kg-d)-1
(mg/kg-d)-1


1988


1988






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
21
0.3
Y/N
Y/N
mg/L
ug/L
ug/L


2006



Teratogen



Prevalence Magnitude
5 5 Li
HRL Ratio(s)
NCHRL/STORET90%: 0.092
CARHRL/STORET90%: 0.0013
Notes
Reference Dose
Reference Dose; Basis NOEL 0.3 mg/kg-d. U.S. DOD, 1983
Reference Dose
Reference Dose
Int-Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year AD-A092-531
Supplemental Data




EPAHA





EPA; RAIS
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   RDX
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 180 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental water data
STORE!

HRL Ratios (HRL/STORET 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples
23



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
23



Number of
States



%
PWSs/Sites/Sam
pies with
detects
100



Units
States
States
States
Minimum value of
Detects
15

Non-cancer: 0.092
Amount Range
>500K - 1 M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
270









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
140
90% of
Detects
229
Units
ug/L

Cancer: 0.0013



Notes






High explosive
Value

195.4
0.87

6.30E-08
59.7

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = biodegrades fast with acclimation







-------
sec-Butyl benzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 181 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
sec-Butylbenzene
5904
135988
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











4.42

2,240


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral -alteration of classical conditioning




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



10.3

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
3 6 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 1.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 24-week oral rat study; VCVGH "Vrednie chemichescie
veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances Galogenated
hydrocarbons) Bandman A.L. etal., Chimia, 1990. Volume(issueXpage/year -,179,1990
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   sec-Butyl benzene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 182 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,343
22,974


28
34


0.227
0.148


0.03
0.1


19.8
22


0.7
0.6


10
4.6


19.8
22

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309


Amount
Released



# PWSs/Sites
sampled

25


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0.58


Number of
States



% PWSs/Sites
with detects

0.005


Units
States
States
States
Minimum value of
Detects

Non-cancer: 1.03
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



11


Year



Maximum
value of
Detects

0.39


2.81


11


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent for coating compositions, organic synthesis, plasticizer, and surface active agents (HSDB)
Value
15
7,200
4.57

1.80E-02
17.6
15
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = biodegrades slowly







-------
Strontium
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 183 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Strontium
18848
7440246
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.6
0.6
0.6
2











Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1992
2006

2004











Critical Effect

Rachitic bone


Musculo-skeletal effects











Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1





1993






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


20
4,200

Y/N
Y/N
mg/L
ug/L
ug/L


2006







Prevalence Magnitude
10 10 Li
HRL Ratio(s)
NCHRL/NIRS90%:3.88
Notes
Reference Dose
Reference Dose; Storey, 1961 ; Marie et al., 1985; Skoryna, 1981; UF = 300; Rat; Basis NOAEL = 190
mg/kg-d
Reference Dose
Reference Dose; IRIS
Minimal Risk Level; UF = 30; MRL-Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were
identified for potency scoring.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Strontium
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 184 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



980



99.1



1.5



43,550



178



1,080



7,340
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 3.88
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for strontium carbonate: In pyrotechnics; steel production; catalyst; lead scavenger (HSDB); naturally-occurring
Value





11

Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BST






Notes
assumed persistent; All use and env. fate data are for strontium carbonate; BST = biodegrades sometimes/recalcitrant







-------
Tebuconazole
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 185 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tebuconazole
69191
107534963
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.029




0.03









1,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2008




1994










Critical Effect
Decreased body weights, absolute brain weights, brain
measurements and motor activity in offspring














Behavioral - food intake (animal)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



C

mg/L
(mg/kg-d)"1
(mg/kg-d)-1





2008






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
96 L' L
HRL Ratio(s)
NC HRL/GWC EEC: 9.09
Notes
Reference Dose; Basis = LOAEL 8.8 mg/kg-d; UF = 300. Federal Register: May 14, 2008 (Volume
74, Number 94), pp 27748-27756.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Oral study- rabbit; NTIS Nationa Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0545183




OPP; 73 FR No. 94, pp 27748-27756.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tebuconazole
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 186 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total




Amount
Released
478,568





Units
Ibs/yr
Ibs/yr
Ibs/yr




Number of
States
16





Units
States
States
States




Year
1997













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 14 ug/L
Ground water chronic: 23.1 ug/L

HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 9.09
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







Fungicide (HSDB)
Value


3.7

1.45E-10
36
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
PBT; BST = biodegrades sometimes/recalcitrant







-------
Tebufenozide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 187 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tebufenozide
69514
112410238
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018




0.02





8.7




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999




2003










Critical Effect
Growth retardation, alterations in hematology
parameters, changes in organ weights, and
histopathological lesions in the bone, spleen and liver




Effect on erythrocytes, periferal hemolytic anaemia. Gross
and histopathologica lesions in the spleen (congestion,
pigment, and extra-medullary haematopoiesis)





Blood - normocytic anemia, Blood - thrombocytopenia




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



126

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
9 5 Li
HRL Ratio(s)
NC HRL/SWC EEC: 8.4
Notes
Reference Dose; Basis NOAEL = 1 .8 mg/kg-d, UF = 100. Federal Register 64 FR, No. 203, pp
56690-56697, October 21, 1999.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year study in dog; FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year 64, 16851, 1999
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tebufenozide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 188 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
104,413





Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
17





Units
States
States
States



Year
1997











Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 15 ug/L
Ground water chronic: 1.19ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.4
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







nsecticide (HSDB)
Value


4.25

1.26E-08
0.83
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
PBT; BST = biodegrades sometimes/recalcitrant







-------
Tellurium
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 189 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tellurium
23035
13494809
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










25




20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










Maternal toxicity




Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

175

Y/N
Y/N

ug/L
ug/L






Teratogen



Prevalence Magnitude
49 Li
HRL Ratio(s)
NCHRL/NIRS 90%: 0.673
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; No Observed Effect Leve ; Johnson et al., 1988
Lowest Observed Adverse Effect Level
Supplemental Data


Mouse; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
Izmerov, N.F., et al., Moscow, Centre of Internatonal Projects, GKNT, 1982 Volume(issue)/page/year -
,107,1982








UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tellurium
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 190 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



4



0.4



15



370



22



260



360
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.673
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for sodium tellurite: Bacteriology, medicine (HSDB); naturally-occurring
Value







Units
length of time
L/kg
unitless
L/kg
unitless
mg/L

Degradation
Code
BST






Notes
assume persistent; All use and env. fate data are for sodium tellurite; BST = biodegrades sometimes/recalcitrant







-------
Terbufos
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 191 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Terbufos
22585
13071799
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic? NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005

0.00005
0.000025

0.0002










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date


2006


1989










Critical Effect
Plasma ChE inhibition















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification



D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1





1988






Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.002
0.35

Y/N
Y/N
mg/L
ug/L
ug/L


2006







Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1.67
Notes
Reference Dose; Basis = NOAEL 0.005 mgrtsg-d; UF = 100.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Cancer classifications were used for screening, but no related quantitative cancer risk data were identified for
potency scoring.




Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
      Terbufos
      CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 192 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water

CAL DHS
STORE!
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,,2, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118


Amount
Released
6,515,603

n
PWSs/Sites/Sa
mples


n
PWSs/Sites/Sa
mples
61
915
22


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
#with Detects
0
11
0.31


Number of
States
37

%
PWSs/Sites/Sam
pies with
detects
0
0
%
PWSs/Sites/Sam
pies with
detects
0
1.2
0.0021


Units
States
States
States
Minimum value of
Detects


Minimum value of
Detects

0.1
Non-cancer: 1.67
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.56


Year
1997

Maximum value
of Detects
Not Detected
Not Detected
Maximum value
of Detects

3.2
0.017


0.21


0.56


Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
ug/L National Aggregate
ug/L National Aggregate
Notes


Median value of
Detects


Median value of
Detects

0.185
95% of Detects
Not Detected
Not Detected
90% of Detects

0.202
Notes
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Cancer:



Pesticide Pilot Mentoring Program (USGS/EPA)

Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





nsecticide (HSDB)
Value
38
500-5,000
4.48

2.40E-05
5.07
14
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = biodegrades slowly with acclimation







-------
Terbufos sulfone
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 193 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Terbufos sulfone
37071
5607016
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
1 1
Scores based on parent Scores based on parent
HEALTH EFFECTS DATA1 - See parent Terbufos
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Plasma ChE inhibition















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N

ug/L
ug/L











3-model Categorical Prediction
NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 .67 (NAWQA data and HRL
for parent terbufos)
Notes
Reference Dose - FOR PARENT TERBUFOS
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level
Based on data for parent terbufos

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
      Terbufos sulfone
      CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 194 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Finished Water Occurrence Data FOR TERBUFOS - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0
0
0

0


Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects

Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data FOR TERBUFOS - PARENT
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
FOR TERBUFOS - PARENT
CAL DHS
STORE!
PPMP finished water
PPMP ambient water
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118



Amount
Released



n
PWSs/Sites/Sa
mples
61
915


22



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
11
2
0
0.31



Number of
States



%
PWSs/Sites/Sam
pies with
detects
0
1.2
0.9
0
0.0021



Units
States
States
States
Minimum value of
Detects

0.1


Non-cancer: 1.67
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.56



Year



Maximum value
of Detects

3.2
0.016

0.017



0.21



0.56



Units for Mag
data

ug/L
mg/L
mg/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

0.185


90% of Detects

0.202


Units for Mag No(es
data
ug/L
ug/L
ug/L
ug/L
Cancer:



Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx

Pesticide Pilot Montoring Program (USGS/EPA) FROM TERBUFOS O-
ANALOGUE SULFONE
Pesticide Pilot Montoring Program (USGS/EPA) FROM TERBUFOS O-
ANALOGUE SULFONE
NAWQA data and HRL for Parent Terbufos



Pesticide degradate
Value
38



2.21 E-08

21
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with ace mation







-------
Thiodicarb
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 195 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Thiodicarb
38116
59669260
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03




0.03










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1998




2000










Critical Effect
Extramedulary hematapoesis and decreased red blood cell
cholinesterase activity















Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0188


B2

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


210
1.86
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 6 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 8.1
CAR HRL/SWC EEC: 0.07
Notes
Reference Dose; Basis NOEL = 3.3 mg/kg-d (males) and 4.5 mg/kg-d (females); UF = 100; chronic rat
study.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











CACART; EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thiodicarb
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 196 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
821,267
0.05
1,430



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
27
1
3



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 26 ug/L
Ground water chronic: 0 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.1
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.07







nsecticide (HSDB)
Value


1.7

9.33E-07
35
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
Thiophanate-methyl
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 197 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Thiophanate-methyl
27753
23564058
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.08
0.08

0.08

0.08





1.2



2,270
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
2004
1986



1998










Critical Effect
Thyroid and liver effects and decreased body weight
Decreased body weight, decreased spermatogenesis and
histological evidence of hyperthyroidism









Endocrine - evidence of thyroid hypofunction, Endocrine -
changes in thyroid weight, Nutritional and Gross Metabolic
- weight loss or decreased weight gain



Sense Organs and Special Senses (Eye) - mydriasis
(pupillary dilation), Behavioral - somno ence (general
depressed activity), Behavioral - convulsions or effect on
seizure threshold
Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0116


C

mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

560
3.02
Y/N
Y/N

ug/L
ug/L






Female & male reproductive toxicity



Prevalence Magnitude , „ ,
10 6 Li L
HRL Ratio(s)
NC HRL/SWC EEC: 45.9
CAR HRL/SWC EEC: 0.248
Notes
Reference Dose; Basis NOEL = 8 mg/kg-d; UF = 100; chronic dog study.
Reference Dose; Basis = NOEL 8 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FEREAC Federal Register. (U.S. Government Printing Office,
Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year 67,14944,2002
Supplemental Data


TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 23,606,1972





OPP


EPA
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thiophanate-methyl
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 198 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
453,792
0
92



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
40
0
3



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 12.2 ug/L
Ground water chronic: 3.03 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 45.9
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.248







Fungicide (HSDB)
Value

14.32
1.4

2.94E-13
438.9

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = biodegrades fast







-------
Toluene diisocyanate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 199 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Toluene diisocyanate
29421
26471625
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD501
CTDJPN Lowest Oral LD501
RTECS Lowest Oral LD501
Value









30

85.7




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Burns throat immediately.

Related to Chronic Data - death




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


0.039

2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1






1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


210
0.9
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-251,1986
Supplemental Data






Applies to m ixture of 2,4- and 2,6- isomers.



CACART; IARC; OEHHA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Toluene diisocyanate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 200 of 1124
OCCURRENCE DATA

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

1
129,143
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

1
31
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M - 1 B
>500M - 1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n plastics manufacture (NTP)
Value

9,114
3.74

1.11E-05
37.57
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
Tribufos
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 201 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tribufos
2814
78488
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.001
0.00003

0.00003







4.08



77
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect
Plasma ChE inhibition










Gastrointestinal - other changes, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
other hydrolases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - peptidases



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
98 Li
HRL Ratio(s)
NC HRL/SWC EEC: 3.89
Notes
Reference Dose; Basis = NOAEL 0.1 mg/kg-d; UF = 100.
Reference Dose; Basis NOAEL 0.1 mg/kg-d; Abou-Donia etal., 1979
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 43 week study in rodent; FATOAO Farmakologiya i Toksikologiya
(Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.2- 1939- Volume(issue)/page/year 38,96,1975
Supplemental Data


85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1188,1986









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tribufos
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 202 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water




Amount
Released
4,918,265
4
7
n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration




Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0




Number of
States
16
1
1
%
PWSs/Sites/Sam
pies with
detects
0
0




Units
States
States
States
Minimum value of
Detects






Year
1997
2004
2004
Maximum
value of
Detects


Surface water chronic 1.8ug/L












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects


95% of
Detects


Units for Mag
data
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic 0 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 3.89
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







nsecticide; cotton defoliant (HSDB)
Value

1,888
5.7

2.94E-07
2.3

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BF






Notes
BF = biodegrades fast







-------
Triethylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 203 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Triethylamine
5379
121448
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1



460
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Brain and Coverings - other degenerative changes



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2.33

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 9
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-week oral rat study; WDZAEK Weisheng Dulixue Zazhi.
Journal of Health Toxicology. (Weisheng Du ixue Zazhi Bianjibu, Dongdaqiao, Chaoyang Menwai,
Beijing, Peop. Rep. China) V.1- 1987 Volume(issue)/page/year 4,45,1990
Supplemental Data


AMIHBCAMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54.
For publisher information, see AEHLAU. Volume(ssue)/page/year 4,119,1951









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Triethylamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 204 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released

12,000
1,167,219
# PWSs/Sites
sampled





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States

14
35
% PWSs/Sites
with detects





Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year

2004
2004
Maximum
value of
Detects













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; stabilizer; in herbicides/pest c des; in consumer products; food addit ve; photographic chemical; in carpet c eaners (HSDB)
Value

107.2
1.45

1.49E-04
73,700
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = biodegrades slowly with acclimation







-------
Triphenyltin hydroxide (TPTH)
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 205 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Triphenyltin hydroxide (TPTH)
2738
76879
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0003




0.0005





0.15




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1999




1970










Critical Effect
Decreased white blood cells










Blood - changes in other cell count (unspecified), Blood -
changes in leukocyte (WBC) count




Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

18.3


B2

mg/L
(mg/kg-d)-'
(mg/kg-d)-1
(mg/kg-d)-1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

2.1
0.0019
Y/N
Y/N

ug/L
ug/L






Teratogen; Developmental



Prevalence Magnitude
10 6
HRL Ratio(s)
NC HRL/SWC EEC: 0.33
CAR HRL/SWC EEC: 0.0003
Notes
Reference Dose; OPP RED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day study in guinea pig; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year4,35,1966
Supplemental Data











EPA; CACART
UMD; CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Triphenyltin hydroxide (TPTH)
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 206 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total





Amount
Released
660,971
0
0





Units
Ibsfyr
Ibs/yr
Ibs/yr





Number of
States
26
0
0





Units
States
States
States





Year
1997
2004
2004















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic 6.4 ug/L
Ground water chronic 0 ug/L
Notes


HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 0.33
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.0003







Pesticide (NTP)
Value

2,000
3.53

4.26E-07
0.4

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Urethane
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 207 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Urethane
2189
51796
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










0.9
78




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










2005





Critical Effect










Decreased survival
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - changes in leukocyte
(WBC) count




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


1

2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1






1987





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

6.3
0.035
Y/N
Y/N

ug/L
ug/L





Developmental
Teratogen



Prevalence Magnitude ,
7 6 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Food and Chemical Toxicology 43 (2005) 1-19
Lowest Observed Adverse Effect Level; 1 3 week oral study in rats; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NIH-96-
3937
Supplemental Data








Vol. 7, Suppl. 7; 1987

IARC; CACART; OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Urethane
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 208 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released

0
96,050
# PWSs/Sites
sampled





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States

0
7
% PWSs/Sites
with detects





Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year

2004
2004
Maximum
value of
Detects













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Paint ingredient (NTP)
Value


-0.15

6.40E-08
480,000
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = Biodegrades Slowly







-------
Vanadium
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 209 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Vanadium
18882
7440622
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.007
0.003



1.8


960




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




1992



2001







Critical Effect




Minor renal effects (altered renal function as indicated
by increased plasma urea, and mild histological
changes).



Kidney lesions and increases in plasma urea and uric acid







Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



21

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude , „ ,
10 8 Li L
HRL Ratio(s)
NCHRL/NIRS90%:0.913
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; HEAST
Minimal Risk Level; MRL-Int; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; IOM 2001 Dietary Reference ntakes
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; Domestic mammal
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vanadium
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 210 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



146



14.76



3.1



70.4



7.27



23



45
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.913
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for vanadium pentoxide: Chemical intermediate; catalyst; (HSDB); naturally-occurring
Value





8,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; All use and env. fate data are for vanad um pentoxide; BST = biodegrades sometimes/recalcitrant







-------
Vinclozolin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 211 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Vinclozolin
35005
50471448
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.012
0.025

0.025

0.01










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986



1995










Critical Effect
Histopathological les ons in the lungs, iver, ovaries &
eyes. Q1 * 0.0638 (mg/kg-day)-1 .Group C. See CAR















Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor (oral)
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0638




mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

84
0.549
Y/N
Y/N

ug/L
ug/L






Developmental



Prevalence Magnitude , „ ,
10 5 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 8.94
CAR HRL/SWC EEC: 0.058
Notes
Reference Dose; Basis = NOAEL 1 .2 mg/kg-d; UF = 1 00.
Reference Dose; Basis = NOEL 2.5 mg/kg-d; UF = 100.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











EPA
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vinclozolin
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 212 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



Amount
Released
121,959
0
0



Units
Ibsfyr
Ibs/yr
Ibs/yr



Number of
States
26
0
0



Units
States
States
States



Year
1997
2004
2004









Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
Surface water chronic: 9.4 ug/L
Ground water chronic: 0 ug/L

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer: 8.94
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer: 0.058







Fungicide (HSDB)
Value

289
3.1

1.33E-08
2.6

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = biodegrades sometimes/recalcitrant







-------
Ziram
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 213 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ziram
5947
137304
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.016




0.003




1.6
1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1996










Critical Effect
Decreased body weight gain




Decreased body weight





Gastrointestinal - hypermotility, diarrhea




Cancer Data
EPA Lifetime Cancer Risk, 104
OPP Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification

0.0611

Suggestive (not
quantified)
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



112
0.57
Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude ,
10 7 L
HRL Ratio(s)
NC HRL/SWC EEC: 56.6
CAR HRL/SWC EEC: 0.288
Notes
Reference Dose; Basis = NOAEL 1 .6 mg/kg-d; UF = 1 00.
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; Group ADI for Ferbam and Ziram
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
OPP
Lowest Observed Adverse Effect Level; NNG ADV Nippon Noyaku Gakkaishi. Journal of the Pesticide
Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome, Toshima-ku, Tokyo 1 70,
Japan) V.1- 1976- Volume(issue)/page/year 17,3155,1992
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ziram
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 214 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total




Amount
Released
1,992,552





Units
Ibsfyr
Ibs/yr
Ibs/yr




Number of
States
29





Units
States
States
States




Year














Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Supplemental Water Data
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 1 .98 ug/L
Non-cancer: 56.6
Amount Range
>500K - 1 M
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Ground water chronic: 0.03 ug/L
Cancer: 0.288







Synthetic rubber chemical (NTP); fungicide
Value




6.20E-10


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades Fast with Acclimation







-------
(d)-Limonene
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 215 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
(d)-Limonene
17273
5989275
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
IPCS-CICAD TDI
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.1

500
30




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1993




Critical Effect








ncreased relative liver weight

Decreased body weight gain
Kidney, Ureter, Bladder - other changes in urine
composition, Kidney, Ureter, Bladder - other changes




Prevalence Magnitude
9 6 NLi
HRL Ratio(s)
NC HRL/NREC ASW MED: 700
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
IPCS Tolerable Daily Intake
No Observed Effect Level
Supplemental Data; NTP Study Report TR-347
Lowest Observed Adverse Effect Level; oral study in rat; FCTOD7 Food and Chemical Toxicology.
(Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year31,125,1993
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

700

Y/N
Y/N

ug/L
ug/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   (d)-Limonene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 216 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NREC ASW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
6.39
1.47
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer: 700
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year

2004
2004
Maximum
value of
Detects




Median value of
Detects
1
0.39



90% of
Detects





99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Used in flavorings, fragrances, cosmetics, as a solvent, wetting agent and the manufacture of resins, insecticide, synthetic intermediate (HSDB)
Value

1,300
4.57

0.026
13.8
19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
Biodegrades slow (PBT)







-------
(Hydroxyimino)cyclohexane
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 217 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
(Hydro xyiminojcyclohexane
4125
100641
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











17.86




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Endocrine - changes in spleen weight, Blood -
changes in erythrocyte (RBC) count, Blood - changes
in leukocyte (WBC) count




Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information,
see TOSCF2 Volume(issue);pagefyear5,117,1985
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



41.7

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   (Hydroxyimino)cyclohexane
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 218 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days

0.84

8.05E-06
18,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1,1,1 -Trichloropropanone
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 219 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
1 ,1 ,1 -Trichloropropanone
10061
918003
Attribute Scores
Potency Severity

Prevalence Magnitude
10 7
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N
mg/L
ug/L
ug/L











3-model Categorical Prediction

HRL Ratio(s)
No HRL data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 ~6 cancer risk was used.

-------
    1,1,1 -Trichloropropanone
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 220 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
DBP ICR finished water














53









16.97




1.7










Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006 and related
documentation

HRL Ratios (no HRL data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released



# PWSs/Sites/
Samples
12






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
10






Number of
States



% PWSs/Sites/
Samples w/
Detects
83






Units
States
States
States
Minimum value of
Detects
Not detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year



Maximum
value of
Detects
7
















Units for Mag
data

ug/L
ug/L
ug/L

ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes








National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.8

90% of
Detects


Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci. &
Technol., 40(23), pp. 7175-7185 (and related documentation).

Cancer:







Disinfection By-Product
Value
60 days
8.7
1.12

2.20E-06
7,450
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
1,1,2,2-Tetrachloroethane
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 221 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,1 ,2,2-Tetrachloroethane
2878
79345
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.00005
0.06
0.04











Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




1996











Critical Effect


Decreased body weights; increased white blood cell
counts, hepatic fat content and pituitary ACTH content
Hepatocellular vacuo zation and increases in absolute
and relative












Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.13
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL rat, Microbioligica Associates, 1994. UF = 300
Minimal Risk Level; Basis LOAEL 43, rat, NCI 1 987; UF = 1 ,000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.02
0.2
0.27

C
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

0.002
0.35

Y/N
Y/N
mg/L
ug/L
ug/L










EPA; RAISHE; OEHHA; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    1,1,2,2-Tetrachloroethane
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 222 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

20,407
24,800


91
19


0.446
0.0766


0.05
0.1


200
2


0.5
0.5


2.74
1.5


112
2

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,317


# Sam pies
Amount
Released

5
3,185
# PWSs/Sites/
Samples
134

3


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0

0.069


% Samples with
detects
Number of
States

1
5
% PWSs/Sites/
Samples with
detects
0

0.02


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects


Non-cancer: 0.13
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.38


Maximum
value of
Detects
Year

2004
2004
Maximum
value of
Detects


0.14


Median value of
Detects
0.38


90% of
Detects
0.38


99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


90% of
Detects


Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





ndustrial solvent; former pesticide; in manufacture of paints, varnish, rust removers; in soil sterilization and weed k Her, insecticide formulations; chemical intermediate (HSDB)
Value
>58 days
106.8
2.39

0.00037
2,870

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
1,2,3,4-Tetrahydronapthalene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 223 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,3,4-Tetrahydronaphthalene
5285
119642
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













2,860


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date













1982


Critical Effect













Cataract


Prevalence Magnitude
7 3 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Ref: Hayes, Wayland J., Jr. Pesticides Studied in Man. Baltimore/London: Williams and Wilkins
1982., p.122


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,2,3,4-Tetrahydronapthalene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 224 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year

2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; paint remover; nsecticide (HSDB)
Value

1,800


0.0017

23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)





PBT

-------
1,2,3-Trichlorobenzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 225 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,3-Trichlorobenzene
3257
87616
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value







0.0015


7.7
77.1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg(kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







1992



1988




Critical Effect










Mild to moderate histopathological changes in the
liver, thyroid and Wdney
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Nutritional and Gross
Metabolic - weight loss or decreased weight gain




Prevalence Magnitude
5 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 18
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER. Ref: HC2004. Basis NOEL, rat, Cote, etal., 1988. UF =5000
Lowest Observed Adverse Effect Level; oral study in rat; DCTODJ Drug and Chemical Toxicology.
(Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year
11,11,1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



53.9

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    1,2,3-Trichlorobenzene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 226 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,876
22,532


63
43


0.489
0.191


0.04
0.03


15
2.4


0.5
0.5


3
1.4


15
2.4

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309

# Sam pies
Amount
Released



# PWSs/Sites/
Samples
11,833

3

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
6

0.07

% Samples with
detects
Number of
States



% PWSs/Sites/
Sam pies with
detects
0.05

0.02

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.6

Non-cancer: 18
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.102

Maximum
value of
Detects
Year

2004
2004
Maximum
value of
Detects
7

0.068

Median value of
Detects
0.102

90% of
Detects
0.102

99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.7

90% of
Detects
6.5

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





ndustrial solvent; chemical intermediate; termite control (HSDB)
Value

2,500-63,000
4.05

0.0012
18

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
1,2,4,5-Tetrachlorobenzene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 227 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,4,5-Tetrachlorobenzene
3799
95943
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0003

0.003



0.00021



0.0432




Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987





1992



1988




Critical Effect

Kidney lesions









Liver - changes in liver weight




Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis NOAEL = 0.34, rat, Chu et al. 1984. UF = 1000
Reference Dose
Reference Dose; Basis NOAEL, rat, Chu etal. 1984. UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; ITER. Basis NOAEL = 2.1 mg-kg/d, rat, NTP 1991. UF = 10,000
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB92-1 28388
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2.1

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,2,4,5-Tetrachlorobenzene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 228 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate for herbicides; former insectic
Value
60 days
1,186
4.64

0.001
0.595

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST










Maximum
value of
Detects


Year

2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





de (HSDB)
Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
1,2,4-Trimethyl benzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 229 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2,4-Trimethylbenzene
3775
95636
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.05





100

114




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1993




Critical Effect



dec in body wt gain; clinical observations; inc
iver/kidney wt







Peripheral Nerve and Sensation - recording from afferent
nerve, Peripheral Nerve and Sensation - recording from
peripheral motor nerve, Nutritional and Gross Metabolic -
weight loss or decreased weight gain




Prevalence Magnitude
6 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL, rat, IITR1 1995. UF = 3000.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; JJATDK JAT, Journal of Applied Toxicology.
(John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO191UD, UK) V.1- 1981-
Volume(issue)/page/year 13,123,1993
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


350

Y/N
Y/N

ug/L
ug/L
1987









EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,2,4-Trimethyl benzene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 230 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,755
22,968


106
177


0.831
0.771


0.02
0.1


77
137


1
0.8


10
5.6


65.6
70.6

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,233

# Sam pies
Amount
Released

5,676
7,700,757
# PWSs/Sites/
Samples
11,886

473

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
35

11.2

% Samples with
detects
Number of
States

37
54
% PWSs/Sites/
Samples with
detects
0.29

0.003

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5

Non-cancer: 350
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



260

Maximum
value of
Detects
Year

2004
2004
Maximum
value of
Detects
19

0.024

Median value of
Detects
0.201

90% of
Detects
10

99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1

90% of
Detects
5.5

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermed ate; vermifuge (HSDB)
Value

718
3.63

0.0062
0.252
57
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
1,2-Diphenylhydrazine
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 231 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,2-Diphenylhydrazine
5454
122667
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude .,, .,, „

HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
0.005
0.8
0.87

B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1






1986







IRIS





Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.05
Y/N
Y/N

ug/L
ug/L










EPA; RAIS; OEHHA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
      1,2-Diphenylhydrazine
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 232 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

0
5
# PWSs/Sites/
Samples
65



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects
Number of
States

0
1
% PWSs/Sites/
Sam pies with
detects
0



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Not Detected



Median value of
Detects


90% of Detects


99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of Detects
Not Detected

Units for Mag
data


Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermediate; evaluated as insecticide (HSDB)
Value

3,481
2.94

4.38E-09
221

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades sow with acclimaton (BIODEG)







-------
1,2-Epoxy-4-(epoxyethyl)cyclohe
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 233 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,2-Epoxy-4-(epoxyethyl)cyclohexane
4566
106876
Attribute Scores 3-model Categorical Prediction
Potency Severity
8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
1 7
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







1994











Vol. 60; cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

ug/L
ug/L










IARC, CACART; Clear evidence of carcinogenicity in male and female rats and mice (NTP).

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,2-Epoxy-4-(epoxyethyl)cyclohe
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 234 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1990
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical and polymer intermediate (HSDB)
Value
1 5 days

0.44

1.42E-07
35,200
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1,3-Cyclopentadiene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 235 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Cyclopentadiene
7730
542927
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















113
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 8 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0535718
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7.91

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,3-Cyclopentadiene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 236 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days
89.7
2.25

0.00793
471

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1,3-Dibromo-5,5-dimethylhydanto
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 237 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,3-Dibromo-5,5-dimethylhydantoin
2748
77485
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.437



250
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Endocrine - evidence of thyroid hypofunction




Prevalence Magnitude
3 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volu me(issue)/page/year 36(1 0),1 08,1 971
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.02

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,3-Dibromo-5,5-dimethylhydanto
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 238 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Molluscicide; slim
Value
38 days

-0.94



51
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





cide (ChemlDPIus)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
1,3-Dichloropropene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 239 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Dichloropropene
7722
542756
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.02
0.03
0.03







2.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1974




Critical Effect
Decreased body weight gain and increased incidence of
basal cell hyperplasia of the nonglandular mucosa of the
stomach
forestomach

chronic irritation







Gastrointestinal - changes in structure or function of
endocrine pancreas, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
hydrolases




Prevalence Magnitude
4 6 Li
HRL Ratio(s)
NC HRL/NCOD R1 90%: 97.2
CAR HRL/NCOD R1 90%: 0.16
Notes
Reference Dose; Stott, et al. 1995
Reference Dose, Stott etal., 1995, Basis BMD = 2.2 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, Stott etal., 1995, BMDL/BMD, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 39(1), 94,1 974
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
OPP Slope Factor
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.04
0.1
0.091
1.22

B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







2000
1999













Vol. 41, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
WHODWQ
Health Reference Level (HRL)2 cancer
Y

1
175
20
0.287
Y/N
Y/N
mg/L
ug/L
ug/L
ug/L












EPA, RAISHE, OEHHA, OPP, IARC, CACART

Drinking Water Equivalent Level

Substance Guideline Value; For excess risk of 1 0-5

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,3-Dichloropropene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 240 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

9,164
16,787


15
58


0.16
0.35


0.5
0.2


2.0
39.0


1.0
0.5


1.8
0.99


2.0
39.0

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released
34,717,237
0
4,471
# PWSs/Sites/
Samples
12,117




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4




% Samples with
detects


Number of
States
20
0
9
% PWSs/Sites/
Sam pies with
detects
0.03




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.86

Non-cancer: 97.2
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
130




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
2.8

90% of
Detects
92.1

Units for Mag
data
ug/L

Cancer: 0.16



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





pesticide; in organic synthesis (HSDB)
Value
38 days
80.8
2.03

0.00355
2,800
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
1,3-Diisopropyl benzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 241 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,3-Diisopropylbenzene
4042
99627
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.25



3,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral - muscle contraction orspasticity,
Behavioral - alteration of classical conditioning, Blood •
changes in erythrocyte (RBC) count




Prevalence Magnitude
5 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year36(9),18,1971
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.58

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,3-Diisopropyl benzene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 242 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year

2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value
38

4.9

2.00E-02
4.33
8
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
1,4-Benzoquinone dioxime
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 243 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,4-Benzoquinone dioxime
4434
105113
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











5.94




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1964




Critical Effect











Behavioral - alteration of classical conditioning,
Nutritional and Gross Metabolic - weight loss or
decreased weight gain, Biochemica - Enzyme
inhibition, induction, or change in blood ortissue
levels - true cholinesterase




Prevalence Magnitude
3 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 29(10),15,1964
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1







1999











Vol. 29, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



13.9

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   1,4-Benzoquinone dioxime
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 244 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rubber additive (HSDB)
Value
1 5 days

1.49

3.74E-10
4,550
29
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1,4-Butanediol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 245 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,4-Butanediol
4866
110634
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value






0.125


400

30



1,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1968




Critical Effect









Reproductive and developmental toxicity

Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Biochemical - Metabolism (Intermediary) - other
carbohydrates




Prevalence Magnitude .,,„,-,
9 5 NL-L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No severity information is available; Potency/Severity scored on CTDJPN NOEL.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 33(1), 37,1 968
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,800

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,4-Butanediol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 246 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; humectant, Pharmaceuticals (HSDB)
Value

18


1.30E-09
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
1,4-Butynediol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 247 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1,4-Butynediol
4868
110656
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











2



100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1968



1984
Critical Effect











Blood -changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical -Enzyme
inhibition, induction, or change in blood or tissue
levels -true cholinesterase, Biochemical - Metabolism
(Intermediary) - other carbohydrates



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year33(1),37,1968
Supplemental Data


VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. etal., Chimia,
1 994. Volume(issue)/page/year -, 1 53, 1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4.67

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    1,4-Butynediol
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 248 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
8.7 days
1
-0.93

1.70E-11

36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (PBT)







-------
1,4-Cyclohexanedimethanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 249 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,4-Cyclohexanedimethanol
4431
105088
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 7 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/pagefyear
21MAY1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1,4-Cyclohexanedimethanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 250 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in films and coatings (HSDB)
Value
15





36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1,5,9-Cyclododecatriene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 251 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1 ,5,9-Cyclododecatriene
16316
4904614
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,780
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date
















Critical Effect















Behavioral -tremor
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0557883
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1,5,9-Cyclododecatriene
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 252 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Specialty petrochemical (NLM TOXNET)
Value
15

5.5

4.99E-01
0.39
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
11-Aminoundecanoicacid
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 253 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
11-Aminoundecanoic acid
13315
2432997
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











750




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1982




Critical Effect











Kidney, Ureter, Bladder -other changes




Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-216,1982
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1987












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


1,750

Y/N
Y/N

ug/L
ug/L










IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   11-Aminoundecanoicacid
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 254 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer initiator (HSDB)
Value
15

-0.16


1,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
1-Amino-2,4-dibromoanthraquinon
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 255 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Amino-2,4-dibromoanthraquinone
2996
81492
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











90




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood - leukemia, Tumorigenic - active as anti-cancer
agent




Prevalence Magnitude
1 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB97-1 1 6636. 104-week rat study.
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


210

Y/N
Y/N

ug/L
ug/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    1-Amino-2,4-dibromoanthraquinon
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 256 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1986
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate (HSDB)
Value
60 days
18,000
5.31

1.78E-13

5
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
1-Decanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 257 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Decanol
5018
112301
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















4,720
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea
Prevalence Magnitude .,, .,, „
7 3 NL-NL,
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron,
OH 44311) V.19- 1958- Volume(issueypage/year 34,493,1973
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1-Decanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 258 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; chemica intermediate (HSDB)
Value

7,300
4.57

3.20E-05
37
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
1-Dodecanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 259 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Dodecanol
5039
112538
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,170
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Sandman A.L.
et al,, Ghimia, 1994. Volume(issue)/page/year -,1 19,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1-Dodecanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 260 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; chemica intermediate; food additive (HSDB)
Value

15,000
5.13

2.22E-05
4
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
1-Heptanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 261 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Heptanol
4965
111706
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.025



500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Brain and Coverings - other degenerative changes,
Liver - other changes, Kidney, Ureter, Bladder - other
changes




Prevalence Magnitude
3 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -,113,1994
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.058

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   1-Heptanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 262 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent; cosmetic formulations; food additive (HSDB)
Value

74
2.62

1.88E-05
1,670
28
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
1-Hexene
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 263 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Hexene
8242
592416
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1,000




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2000




Critical Effect











Kidney, ureter, bladder, - changes in tubules including
acute renal failure, acute tubilar necrosis




Prevalence Magnitude
9 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, DCTODJ Drug and Chemical Toxicology. (Marcel Dekker,
270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year23,327,2000<
LOAEL, rat
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,333

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1-Hexene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 264 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
8.7 days
1,660
3.39

0.41
50
78
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (PBT)







-------
1-Pentanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 265 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Pentanol
2564
71410
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


VCVQK "Vrednie chemichescie veshestva, galogen 1 kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Sandman A.L.
et al., Chimia, 1994. Volume(issue)/page/year -,107,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1-Pentanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 266 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; synthetic flavor ng agent (HSDB)
Value

4.51
1.51

1.30E-05
22,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
1-Propanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 267 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
1-Propanol
2560
71238
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











600



1,870
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1970




Critical Effect











Endocrine - changes in adrenal weight




Prevalence Magnitude
8 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BIOFX BIOFAX Industrial Bio-Test Laboratories, Inc., Data
Sheets. (1810 Frontage Rd., Northbroolc, IL 60062) Volume(issue)/pagefyear 15-4/1970
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,400

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   1-Propanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 268 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997


Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units

Cancer:



Notes





Solvent; chemica intermediate; former pesticide (HSDB)
Value

33
0.25

7.41 E-06
1,000,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2-(Dimethylamino)ethyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 269 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-(Dimethylamino)ethyl acrylate
13333
2439352
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









4





455
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Epithelial hyperplasia of the forestomach;
hematological effects; decreased body weight gain.





Lungs, Thorax, or Respiration - other changes
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


rat study; EPASR United States Environmental Protection Agency, Office of Pesticides and Toxic
Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History
unknown. Volume(issue)/paqe/year 8EHQ-1 190-1 1 1 9
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



28

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    2-(Dimethylamino)ethyl acrylate
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                   EPA-OGWDW
    August 2009
Page 270 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial Chemical (EPA/SRS)
Value
1 5 days





44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2,3-Dibromopropanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 271 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,3-Dibromopropanol
3812
96139
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















681
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
1 7 Li
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/page;year OTS0528372
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

ug/L
ug/L










IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2,3-Dibromopropanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 272 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year

1990




Maximum
value of
Detects


Year
1997


Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for flame retardants, insectic des, and pharmaceut cals (HSDB)
Value
15
4


6.30E-08
52,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2,4,5-Trichlorophenol
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 273 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4,5-Trichlorophenol
3800
95954
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1



0.003



72



600
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1985





2000



1972




Critical Effect

Liver & kidney pathology (degenerative changes)





mmune system



Liver - other changes, Liver - changes n liver weight




Prevalence Magnitude .,, .,, „

HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; McCollisteret al., 1961. Basis NOEL 100, rat, UF = 1000
Reference Dose
Reference Dose; McCollister et a ., 1961. Basis NOEL/LOEL, rat, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Exon and Koller, 1985. Basis NOAEL, rat.
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; CMSHAF Chemosphere. (Pergamon Press
nc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year
1,153,1972
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2,4,5-Trichlorophenol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 274 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

4,689
18,879
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Fungicide, bacter
Value

1,186
3.72

1.62E-06
1,200

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





cde; industrial preservative; chemical intermediate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
2,4,6-Trichlorophenol
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 275 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4,6-Trichlorophenol
3282
88062
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.0003




0.003



240




Units
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1990




Critical Effect


Increased pups liver weight




mmune system



Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol)




Prevalence Magnitude
1 1 NL!
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose; EPA Health Advisory
Reference Dose
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Exon and Koller, 1985. Basis NOAEL, rat.
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 9(5), 497, 1990
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification
0.3
0.011
0.07

B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
WHODWQ
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

0.01
200
2.1

Y/N
Y/N
mg/L
mg/L
ug/L
ug/L


1994









EPA; RAISHE; OEHHA; IARC; CACART

Drinking Water Equivalent Level
World Health Organization Drinking Water Guideline Value


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
      2,4,6-Trichlorophenol
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
    August 2009
Page 276 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
294


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

1,728
1,906
# PWSs/Sites/
Samples
210



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects
Number of
States

3
3
% PWSs/Sites/
Sam pies with
detects
0



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects


Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects




Median value of
Detects


90% of Detects


99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggragate
Notes



Median value of
Detects


90% of Detects


Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx





Fungicide, bactericide; industrial preservative; chem cal intermediate (HSDB)
Value

1,186
3.69

2.59E-06
800

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (HSDB)







-------
2,4-Dimethylphenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 277 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dimethylphenol
4471
105679
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02

0.02







100



809
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990









1995




Critical Effect

Clinical signs (lethargy, prostration, ataxia) &
hematological changes

Lethargy, prostration, ataxia, hematological changes







Kidney, Ureter, Bladder - changes in kidney weight




Prevalence Magnitude
8 7 Li
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; U.S. EPA, 1989. Basis NOAEL 50, mouse.
Reference Dose
Reference Dose; U.S. EPA, 1989. Basis NOAEL/LOAEL, mouse, UF = 3000.
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TOBHB TAT Toxikologische Bewertung.
Heidelberg, Berufsgenossenschaft der chemischen Industrie Volume(issue)/page/year VI137, 1,1995
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,4-Dimethylphenol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 278 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released

1,137
168,992
# PWSs/Sites/
Samples
171




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0




% Samples with
detects


Number of
States

10
15
% PWSs/Sites/
Samples with
detects
0




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
Not Detected




Median value of
Detects





90% of
Detects





99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





As a disinfectant/bacteriocide/germicide; chemical intermediate for Pharmaceuticals and pesticides; former insect c de/biocide (HSDB)
Value

718
2.3

9.52E-07
7,870

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2,4-Dinitrophenol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 279 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dinitropheno
2166
51285
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002

0.002





10

0.0006
2

49

Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986









1966




Critical Effect

cataract formation in humans

cataract formation







Blood - other changes




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Horner, 1942. Basis LOAEL, human
Reference Dose
Reference Dose; Horner, 1942. Basis LOAEL, human, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve ; oral study in rabbit; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year31(6),3,1966
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

14

Y/N
Y/N

ug/L
ug/L






teratogen




UMD
Drinking Water Equ valent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
      2,4-Dinitrophenol
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 280 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
294


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

502
649
# PWSs/Sites/
Samples
134



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects
Number of
States

1
3
% PWSs/Sites/
Sam pies with
detects
0



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum value
of Detects
Year

2004
2004
Maximum value
of Detects
Not Detected



Median value of
Detects


90% of Detects


99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

99% of Detects
Not Detected

Units for Mag
data


Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermediate; former pestcide (HSDB)
Value

364
1.67

8.61 E-08
2,790

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
2,4-Dinitrotoluene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 281 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Dinitrotoluene
5365
121142
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002
0.002
0.002
0.002






0.896




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1998


1998






1985




Critical Effect

Neurotoxicity, hematological, and bilary effects

Neurotoxicity, heinz bodies, and bilary tract hyperplasia
Hematological






Blood - normocytic anemia, Blood - methemoglobinemia-
carboxyhemoglobin, Blood - changes in other cell count
(unspecified)




Prevalence Magnitude , „ ,
1 10 Li L
HRL Ratio(s)
NC HRL/UCMR 90%: 0.042
CAR HRL/UCMR 90%: 0.00015
Notes
Reference Dose
Reference Dose; Ellis et al., 1985 Basis NOAEL 0.2, dog.
Reference Dose
Reference Dose; Ellis et al., 1985 Basis NOAEL, dog. UF = 100
Minimal Risk Level. Ellis etal., 1979, 1985 Basis NOAEL, dog.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse; JACTDZ Journal of the American College of
Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993.
Discontinued. Volume(issue)/page/year 4(4), 257, 1985
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.005
0.68
0.31

B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1














EPAHA





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.1
14
0.05
Y/N
Y/N
mg/L
ug/L
ug/L






Repro



CACART; EPA; OEHHA; IARC
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,4-Dinitrotoluene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 282 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621


1


0.028


333


333


333


333


333


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

14
6,702
# PWSs/Sites/
Samples
2,614



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects
Number of
States

1
4
% PWSs/Sites/
Samples with
detects
0



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer: 0.042
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year

2004
2004
Maximum
value of
Detects
Not Detected



Median value of
Detects


90% of
Detects


99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer: 0.00015



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermed ate; in propellants (HSDB)
Value

364
1.98

5.41 E-08
270

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
2,4-Toluenediamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 283 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,4-Toluenediamine
3790
95807
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











50




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987




Critical Effect











Kidney, Ureter, Bladder - other changes, Related to
Chronic Data - death




Prevalence Magnitude
2 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TAEHC Environmental Health Criteria (United
Nations Environment Programme. Geneva, World Health Organization) 1- 1976-
VolumefissueVoaae/vear -.1.1987
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

3.2
3.8

B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


117
0.0092
Y/N
Y/N

ug/L
ug/L










RAIS; OEHHA; EPA; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,4-Toluenediamine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 284 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
11,834
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in dyes and photographic developers (HSDB)
Value

120
0.14

9.52E-10
74,800

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
2,5-Xylenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 285 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,5-Xylenol
3795
95874
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















383
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1968
Critical Effect















Behavioral - ataxia, Behavioral - muscle contraction or
spasticity, Lungs, Thorax, or Respiration -dyspnea
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-
71. Discontinued. Volume(issue)/page/year33(7-9), 329,1968. Mouse study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,5-Xylenol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 286 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Petroleum antiox dant; chemical intermediate (HSDB)
Value

440
2.33

7.10E-06
3,540
29
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2,6-Dimethylphenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 287 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,6-Dimethylphenol
8028
576261
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0006

0.0006






0.6
6



296
Units
mg/kg-d
m g/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1968




Critical Effect

Body weight & blood pressure changes; changes in
protein sulfhydryl groups in blood serum & internal
organs; histopatho ogical changes in liver, kidney &
spleen.

body weight changes, histopathological changes of
internal organs






Liver, kidney, spleen
Liver - other changes, Blood - changes in spleen, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol)




Prevalence Magnitude
8 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Veldre and Janes, 1979. Basis NOEL, rat
Reference Dose
Reference Dose; Veldre and Janes, 1979. Basis NOEL/LOEL, rat, UF = 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; ITER; Veldre and Janes, 1979. Basis NOEL/LOEL, rat, UF = 1000
Lowest Observed Adverse Effect Level; oral study in rat; HYSAAV Hygiene and Sanitation (USSR).
English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year 33(7-
9), 329,1968
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4.2

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,6-Dimethylphenol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 288 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year



Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

733
2.36

6.66E-06
6,050

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
2,6-Xylidine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 289 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2,6-Xylidine
3258
87627
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










24
221




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1990




Critical Effect










Decreased survival and decreased body weights,
deceases in red blood cell count, hemoglobin and
hematocrit positive for cancer in male and female rats
IVIice not tested.
Brain and Coverings - changes in brain weight, Liver -
changes in liver weight, Blood - changes in other cell count
(unspecified)




Prevalence Magnitude .,, „
2 4 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-278,1990
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-
278,1990
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


168

Y/N
Y/N

ug/L
ug/L










CACART; IARC; Note: Tested positive for cancer in male and female rats (NTP)

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2,6-Xylidine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 290 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

2,938
5,256
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; pesticide (HSDB)
Value

52
1.84

2.50E-06
8,200
35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST - Biodegrades sometimes/recalcitrant (PBT)







-------
2-Chloro-1-propanol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 291 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Chloro-1-propanol
2842
78897
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











75

111


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect











Nutritional and Gross Metabolic - weight loss or decreased
weight gain, Related to Chronic Data - death

Details of toxic effects not reported other than lethal
dose value.


Prevalence Magnitude
9 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; VCVGK "Vrednie chemichescie veshestva,
galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/paqe/year -,185,1994
Supplemental Data
Clayton, QD.( FE. Clayton (eds). Pattys Industrial Hygiene and Toxicology. Volumes 2A, 2B, 2C,
2D, 2E, 2F: Toxicology 4th ed. New York, NY: John Wiley & Sons, Inc., 1993-1 994 p. 2736


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2-Chloro-1-propanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 292 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>500M-1 B
Units
Ibs/yr
Ibs/yr
Year

1986




Maximum
value of
Detects


Year



Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
15
2


1.70E-06

43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-Ethyl-3-propylacrolein
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 293 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethyl-3-propylacrolein
9266
645625
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


JIHTABJourna of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For
publisher information, see AEHLAU. Volume issue)/page/year 26,269, 1944
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethyl-3-propylacrolein
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 294 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for insecticides and other organics (HSDB)
Value
15




70
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-Ethylhexanal
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 295 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexana
5484
123057
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















2,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
7 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data

Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0534445, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethylhexanal
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 296 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; disinfectant (HSDB)
Value
1 5 days
160


0.00076
400
25
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
2-Ethylhexanoic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 297 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexanoic acid
6263
149575
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










61
629



3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










increased liver weight, hepatocyrte hypertrophy
cytoplamic vacuolization
Behavioral - somnolence (general depressed activity),
Liver - changes in liver weight, Skin and Appendages -
hair




Prevalence Magnitude
7 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Publication Juberg, et al., 1998
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0525547
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



427

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethylhexanoic acid
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 298 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cosolvent and defoamer in pesticides; chemical intermediate (HSDB)
Value

650
2.64

2.90E-06
1,400
28
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
2-Ethylhexanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 299 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexanol
4405
104767
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










125
100

2,053


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect










Decreased body weight, increased liver, kidney, stomach
and testes weights, microscopic changes in the liver and
forestomach
Liver - other changes




Prevalence Magnitude
9 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Publication Astill eral, 1996
Lowest Observed Adverse Effect Level; oral study in rat; VCVQK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashieorganicheskie soedinenia". (Hazardous substances.
Halogen and oxygen containing substances), Bandman A.L. et al,, Chimia, 1994.
Volume(issue)/page/year -,116,1994. The LOAEL was used for Potency scoring because it was
lower than the NO(A)EL from other studies.
Supplemental Data
WHO: Environ Health Criteria Number 32: Toxicological Evaluation of Certain Food Additives and
Contaminants. P. 39 (1993)


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

233

Y/N
Y/N

ug/L
ug/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethylhexanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 300 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; plasticizer; wetting agent; dry cleaning (HSDB)
Value

105


2.65E-05
880
2T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2-Ethylhexenal
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 301 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexena
29251
26266682
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















2,005
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1988
Critical Effect















Behavioral - altered sleep time, chages in motor
activity, muscle contraction and spasticity (including
change in righting reflex)
Prevalence Magnitude .,, „
8 5 NL!'L!
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


QTPZAB, rodent-rat; QTPZAB Qigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992.
For publisher information, see MTPEEI Volume issue)/page/year 32(3),48,1988
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethylhexenal
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 302 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1QOM-500M

Units
Ibs/yr
Ibs/yr
Year
1990
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
1 5 days





24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
2-Ethylhexyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 303 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexyl acrylate
4286
103117
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











3



4,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme
inhibition, induction, or change in blood ortissue
levels - true cholinesterase




Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (V/O MezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year -,16,1 993
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Ethylhexyl acrylate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 304 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year

2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





As monomer; in pa nts (HSDB)
Value
15
430
4.09

0.00043
100
ir
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-Ethylhexyl thioglycolate
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 305 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Ethylhexyl thioglycolate
19121
7659861
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















303
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
6 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und
Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955-
Volume(issue)/page/year 20,575,1974)
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Leve


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
 2-Ethylhexyl thioglycolate
 CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 306 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of
Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
FRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,E, Half life
KQC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year
1997

2004
Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L



ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Value
15 days





22
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
2-Hydroxyethyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 307 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Hydroxyethyl acrylate
9783
818611
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Sense Organs and Special Senses (Eye) - ptosis,
Behavioral - convulsions or effect on seizure
threshold, Gastrointestinal -alteration in gastric
secretion
Prevalence Magnitude
6 5 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 24(4),56,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Hydroxyethyl acrylate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 308 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value

18
-0.21

7.20E-10

39
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
2-Mercaptobenzothiazole
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 309 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Mercaptobenzothiazole
6259
149304
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.65










134




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988




Critical Effect
Decreased body weight. Liver toxicity, increased
kidney weight with increased brown pigment.
ncreased incidence of basophilic tubules in the kidney
cortex.










Liver - changes in liver weight




Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
332,1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

4,550

Y/N
Y/N

ug/L
ug/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Mercaptobenzothiazole
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 31 Oof 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

23,624
644,590
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

4
15
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide; vulcanizer; veterinary medicine (HSDB)
Value


2.41

3.63E-08
120
23
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
2-Methylbutane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 311 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methylbutane
2832
78784
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











357




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Nutritional and Gross Metabolic - weight loss or
decreased weight gain, Related to Chronic Data -
death




Prevalence Magnitude
10 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TIHEEC Toxicology and Industrial Health. (Princeton
Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year
1(3),67,1985
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



833

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Methylbutane
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 312 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate; medication (HSDB)
Value
15
520
2.72

1.4
48
55
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-Methylpyridine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 313 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Methylpyridine
4741
109068
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.0099



674
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood -change in clotting factors, Blood - changes in
other cell count (unspecified), Biochemical - Enzyme
inhibition, induction, or change in blood ortissue
evels - true cholinesterase



Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Behavioral - excitemen
Prevalence Magnitude .,, „
6 5 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Qigiena i Sanitariya. ForEnglish translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volu me(issue)/page/year 33(1 2),1 8,1 968
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 45(12), 62,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.0232

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2-Methylpyridine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 314 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

5
27,839
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
6
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value

96
1.11

9.96E-06


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2-Napthalenamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 315 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Naphthalenamine
3487
91598
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
1 1 NL!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


1.8


1
mg/L
(mg/kg-d)"1
(mg/kg-d)-'
(mg/kg-d)-1







1987












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.0194
Y/N
Y/N

ug/L
ug/L










OEHHA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Napthalenamine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 316 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
5
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Research chemica ; formerly in dye manufacture (HSDB)
Value

1,000
2.28

8.10E-08
6.4
25
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
2-Naphthalenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 317 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Naphthaleno
5876
135193
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









10

0.437



1,335
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1965



1965
Critical Effect









Decreased motor activity

Brain and Coverings -other degenerative changes,
Behavioral -alteration of classical conditioning



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 3 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/OMezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 30(9),22,1965. The LOAEL was used for potency/severity scoring
because it was lowerthan the NO(A)EL from other studies.
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 30(9), 22,1965
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.02

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Naphthalenol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 318 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
n dyes; as lubricant; former anthe
Value

0.45
2.7

4.60E-08
756
24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Year
1998
2002





Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





mintic (HSDB)
Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
2-Nitropropane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 319 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Nitropropane
2889
79469
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












50



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












ncreased anemia, thrombocyte count, and heart weight



Prevalence Magnitude , „ ,
6 5 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; WHO EHC 130



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

9.5


B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol.29, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

117
0.0037
Y/N
Y/N

ug/L
ug/L






Teratogen



CACART; EPA; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Nitropropane
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 320 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

294
25,344
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
6
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Former pesticide; ndustrial solvent additive; chemica
Value
15 days
24.95
0.93

0.000119
17,000
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS











Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





intermediate (HSDB)
Notes
BS = Biodegrades slow (PBT)







-------
2-Propanone oxime
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 321 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Propanone oxime
5638
127060
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
5 7
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L










Clear evidence of carcinogenicity in male/female rats and male/female mice (NTP)

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Propanone oxime
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 322 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
15 days

0.12

7.80E-06
106,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-Pyrrolidone
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 323 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-Pyrrolidone
8675
616455
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











80.4



328
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1979
Critical Effect











Behavioral - food intake (animal), Kidney, Ureter,
Bladder -changes in bladder weight, Blood -changes
in serum composition (e.g. TP, bilirubin, cholesterol)



Behavioral - coma, Lungs, Thorax, or Respiration -
dyspnea
Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information
Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical
nformation. Volume(issue)/page/yearOTS0521310-3
Supplemental Data


TVLMB8 Trudy Volgogradskogo Gosudarstvennogo Mediteinskogo Instituta. Transactions of the
Volgograd State Medical Institute. (Volgogradsk Gosudarstvennyi Meditskinskii Institut, Volgograd,
USSR) 1 961 - Volume(issue)/page/year 31 , 1 60, 1 979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



187.6

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   2-Pyrrolidone
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 324 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in pharmaceutical preparations (HSDB)
Value
1 5 days
17
-0.85

1.06E-09
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
2-tert-Butylhydroquinone
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 325 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
2-tert-Butylhydroquinone
12479
1948330
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.7
0.2


178.6




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgfltg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg-d
mg/kg
mg/kg
mg/kg
Date








1998



1997




Critical Effect








Decreased hemoglobin oand/or hematocritand RBC
counts No evidence for cancer in mice or rats No
evidence of cancer in male or female rats or mice



Blood - changes in spleen, Nutritional and Gross Metabolic
- weight loss or decreased weight gain




Prevalence Magnitude
5 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental data; JEFCA and NTP ADI
Maximum Recommended Daily Dose (MRDD); MRDDs were only used for screening, not for attribute
scoring
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
459,1997
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4,900

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   2-tert-Butylhydroquinone
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 326 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggragate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Antioxidants in fats and oils (HSDB)
Value
38 days





13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
3,3'-Dichlorobenzidine
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 327 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,3'-Dichlorobenzidine
3511
91941
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
2 1 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.008
0.45
1.2

B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1






1990
1987











Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.08
Y/N
Y/N

ug/L
ug/L










EPA, RAISHE, OEHHA, IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3,3'-Dichlorobenzidine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 328 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
2.01
# PWSs/Sites/
Samples
135


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0


% Samples with
detects

Number of
States

0
2
% PWSs/Sites/
Samples with
detects
0


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
>1M-10M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected


Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data
ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





n dyes; curing agent for polymers and rubber products (HSDB)
Value

7,489
3.51

5.11E-11
3.1

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
3,3'-Dimethylbenzidine dihydroc
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 329 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,3'-Dimethylbenzidine dihydrochloride
8575
612828
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











200
1.8



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991
1991



Critical Effect











Endocrine - changes in thymus weight, Blood - changes in
bone marrow (not otherwise specified), Blood - changes in
erythrocyte (RBC) count
ncreased T3, decreased T4 increased THF, cystic
degeneration and foci of cellular alteration in the liver,
nephropathy, hyperplasia of Zymbals gland preputial
and clitoral glands and alveolar epithelium. Clear
evidence of cancer in male and female mice.



Prevalence Magnitude
1 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
390,1991
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page;year NTP-TR-390,1991



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


4.2

Y/N
Y/N

ug/L
ug/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3,3'-Dimethylbenzidine dihydroc
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 330 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year

1990





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n dyes (NTP)
Value






18
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (HSDB)







-------
3,4-Dichloro-1-butene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 331 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,4-Dichloro-1 -butene
9586
760236
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









2




943

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Increased liver weight; increased kidney weight; liver
cell enlargement






Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3,4-Dichloro-1-butene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 332 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
38

2.6

0.0086
420
61
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
3,6-Dichlorosalicylic acid
CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 333 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3,6-Dichlorosa icylic acid
14832
3401807
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











3



660
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1978



1978
Critical Effect











Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels -true cholinesterase,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - catalases, Biochemical -
Enzyme inhibition, induction, or change in bl



Brain and Coverings - recordings from specific areas of
CNS
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issueXpage/year43(10),95,1978; 26-week rat study
Supplemental Data


mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
43(10), 95,1978
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3,6-Dichlorosalicylic acid
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 334 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M

Units
Ibs/yr
Ibs/yr
Year
1986
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (ChemlDPIus)
Value
38 days





14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
3-Chloro-2-methyl-1-propene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 335 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Chloro-2-methyl-1-propene
7957
563473
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











214
75



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1986




Critical Effect











Related to Chronic Data - death
increased instance of forestomach inflammation; clear
evidence of cancer in rats and mice



Prevalence Magnitude
3 4 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week rat study; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-300,1986
Supplemental Data; NTP Report 209



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.14


3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







1995











Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


175
0.25
Y/N
Y/N

ug/L
ug/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3-Chloro-2-methyl-1-propene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 336 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released

0
6,635
# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States

0
3
% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
nsecticide/fungic
Value

81


0.0087
1,400
63
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





de (ChemlDPIus)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
3-Methylpyridine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 337 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Methylpyridine
4735
108996
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












100


400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1985


1986
Critical Effect












increased latency on evoked potentials, increae
latency of pentylenetetrazol-induged seizures.


Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP cites Dyer, et a\., 1 985


rat study; 85JCAE "Prehled PrumysloveToxikolog e; Organicke Latky," Marhold, J., Prague,
Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year -,841,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



233

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3-Methylpyridine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 338 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; chemical intermediate (HSDB)
Value

110
1.2

7.73E-06
1,000,000
45
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
3-Pyridinecarbonitrile
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 339 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
3-Pyridinecarbonitrile
4116
100549
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









5




1,455

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Liver cell enlargement or alteration, liver and kidney
weights were increased.






Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   3-Pyridinecarbonitrile
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 340 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide; chemical intermediate; former fumigant (HSDB)
Value
38 days
37
0.36

2.74E-07
135,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4,4'-Bipyridine
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 341 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Bipyridine
7828
553264
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















172
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1982
Critical Effect















Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral -somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave.,
NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year 10,363,1982. Rat study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   4,4'-Bipyridine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 342 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
38 days

1.28

2.52E-09
4,530
3T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4,4'-Diaminodiphenyl ether
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 343 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Diaminodiphenyl ether
4204
101804
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











3.4




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1986




Critical Effect











Cardiac - EKG changes not diagnostic of specified effects,
Vascular - BP elevation not characterized in autonomic
section




Prevalence Magnitude
2 2 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-wk rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year51(6),31,1986
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.14


2B
mg/L
(mg/kg-d)"1
(mg/kg-d)1
(mg/kg-d)-1







1987











Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7.9
0.25
Y/N
Y/N

ug/L
ug/L










OEHHA, IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4,4'-Diaminodiphenyl ether
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 344 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

621
985
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
38 days
315
2.06

1.50E-11

35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4,4'-Dichlorodiphenyl sulfone
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 345 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Dichlorodiphenyl sulfone
2920
80079
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.005







2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1982




Critical Effect



ncreased incidence or severity of liver
lesions;cetrilobular hypertrophy, centrilobilar
degeneration and bile diet hyperplasia







Brain and Coverings - recordings from specific areas of
CNS, Liver - liver function tests impaired




Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 47(2), 84,1 982
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4,4'-Dichlorodiphenyl sulfone
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 346 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; polymer additive (HSDB)
Value
60 days
7,600
3.9

1.40E-07

10
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
4,4'-Methylenebis(N,N-dimethylb
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 347 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4l-Methylenebis(N,N-dimethyl)benzenamine
4189
101611
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.08
0.046
0.046

B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







1987






IRIS




Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.8
Y/N
Y/N

ug/L
ug/L










RAISHE, EPA, OEHHA, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   4,4'-Methylenebis(N,N-dimethylb
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 348 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1990
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for dyes (HSDB)
Value
60 days
14,700
4.37

1.21E-07
4.14

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
4,4'-Methylenedi(phenyl isocyan
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 349 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4,4'-Methylenedi(phenyl isocyanate)
4194
101688
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















2,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1982
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
zmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year -,63,1 982. Mouse study.
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification




D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1998
1999











Vol., 19, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
    4,4'-Methylenedi(phenyl isocyan
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 350 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,fl, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


^Samples

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Constituent of adhesives and coat ngs (HSDB)
Value

376,000
5.22

8.96E-07
0.829

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
4-Aminobiphenyl
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 351 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Aminobiphenyl
3566
92671
Attribute Scores
Potency Severity
8 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


21


1
mg/L
(mg/kg-d)"1
(mg/kg-d)1
(mg/kg-d)-1







1987











Vol. 1, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.00167
Y/N
Y/N

ug/L
ug/L










OEHHA, IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   4-Aminobiphenyl
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 352 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
1
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; research chemical (HSDB)
Value
38 days
857
2.86

1.50E-07

19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4-Aminodiphenylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 353 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Aminodiphenylamine
4183
101542
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











150




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral - food intake (animal), nutritional and gross
metabolic weight loss of decreased weight gain,
related to chronic data - death




Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 lexicologist. (Soc. of Toxicology, Inc., 475 Wolf
Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year 12,103,1992
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



350

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4-Aminodiphenylamine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 354 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye; chemical intermediate for Pharmaceuticals (HSDB)
Value
38 days
3,100


3.70E-10

2T
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4-Chloro-1,2-diaminobenzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 355 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Chloro-1 ,2-diaminobenzene
3792
95830
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.016


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1







1987











Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



2.19
Y/N
Y/N

ug/L
ug/L










CACART; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4-Chloro-1,2-diaminobenzene
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 356 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>10K-500K
Units
Ibs/yr
Ibs/yr
Year

1986






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate and constituent (HSDB)
Value
38 days

1.28

4.99E-10
6,590
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4-Chlorobenzotrichloride
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 357 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Chlorobenzotrichloride
16518
5216251
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude ,
6 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

20


B2

mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)"1












ung; adenocarcinoma


USEPA, 1987


USEPA, 1987; mouse study

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.00175
Y/N
Y/N

ug/L
ug/L










EPA; CACART; RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4-Chlorobenzotrichloride
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 358 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
60 days
1,812
4.54

0.000193
4.04

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
4-Hydroxy-4-methyl-2-pentanone
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 359 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Hydroxy-4-methyl-2-pentanone
5511
123422
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









30

40



2,520
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Functional and histopatological effects in the kidney

Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis)



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
8 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day rat study; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0557741
Supplemental Data


rat study; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0557732
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4-Hydroxy-4-methyl-2-pentanone
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 360 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value

21
-0.098

4.24E-09
1,000,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
4-Methyl-2-pentanol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 361 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Methyl-2-pentanol
4665
108112
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













2,600


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1986


Critical Effect













Most likely CMS effects based on inhalation data


Prevalence Magnitude ,,, 0 , „
8 5 NL' L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
American Conference of Governmental Industrial Hygienists. Documentation of the Threshold
Limit Values and Biological Exposure Indices. 5th ed. Cincinnati, OH: American Conference of
Governmental Industrial Hygienists, 1986., p. 401


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   4-Methyl-2-pentanol
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 362 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; in lubricants and lacquers (HSDB)
Value

143
1.43


16,400
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
4-Methyl-3-thiosemicarbazide
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 363 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Methyl-3-th iosem icarbazide
18177
6610293
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















14
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral -tremor, Gastrointestina -changes in
structure orfunction of salivary glands,
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude , „
57 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0571100
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   4-Methyl-3-thiosemicarbazide
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 364 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1986
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
1 5 days





40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
4-tert-Butylcyclohexanone
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 365 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-tert-Butylcyc ohexanone
3968
98533
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1975
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
9 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. Forpublisher
information, see FGTOD7. Volume(issue)/page/year 13,729,1975
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   4-tert-Butylcyclohexanone
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 366 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
500M-1 B

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
38 days





16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
4-Vinylcyclohexane
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 367 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
4-Vinylcyclohexene
4103
100403
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











500
200



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Inflamatory lesions and epithelial hyperplasia of the
forestomach, cytologic alteration of the adrenal cortex •
clear evidence of ovarian cancer in female mice and
increased incicence of adrenal adenomas - mortality
too high to make judgment on male and female



Prevalence Magnitude ,,, _
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year
PB91211250
Supplemental Data; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly
U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year PB9121 1250



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1







1994











Vol. 60; cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


467

Y/N
Y/N

ug/L
ug/L










IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   4-Vinylcyclohexane
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 368 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; polymer intermediate (HSDB)
Value

3,300
3.93

0.045
50
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
5-Chloro-o-toluidine
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 369 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Chloro-o-toluidine
3789
95794
Attribute Scores
Potency Severity
5 9
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















464
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1973
Critical Effect















Details of toxic effects not reported other than lethal
dose value

3-model Categorical Prediction
L?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NCILB Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer
Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year NCI-E-C-72-3252,1973
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







2000











Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

ug/L
ug/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   5-Chloro-o-toluidine
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 370 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate; in dye formulations (HSDB)
Value
38 days
234
2.58



26
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
5-Ethylidene-2-norbornene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 371 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Ethylidene-2-norbornene
25357
16219753
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









4






Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Hematological effects






Prevalence Magnitude ,,, _
6 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
Supplemental Data; CTDJPN; male
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



28

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   5-Ethylidene-2-norbornene
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 372 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value

900


0.13

58
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
5-Nitro-o-anisidine
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 373 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Nitro-o-anisidine
4039
99592
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











450




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988




Critical Effect











Liver - liver function tests impaired, Liver - changes in liver
weight, Blood - other changes




Prevalence Magnitude , „
1 8 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day rat study; GTPZAB Gigiena Truda i Professional'nye
Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year
32(3), 48,1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.046
0.049

B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1







1987











Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


1,050
0.714
Y/N
Y/N

ug/L
ug/L










RAISHE, OEHHA, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   5-Nitro-o-anisidine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 374 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L



ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate (HSDB)
Value
38
37.53
1.47

1.47E-08
115

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
5-Nitro-o-toluidine
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 375 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
5-Nitro-o-toluidine
4036
99558
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.033


C
3
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)-1



1990



1990

iver





Vol. 48; mouse study; USEPA 1987


USEPA1987
Vol. 48
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



1.06
Y/N
Y/N

ug/L
ug/L










RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   5-Nitro-o-toluidine
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 376 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
255
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate (HSDB)
Value
38 days
85.4
1.87

1.94E-08
1,878
26
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodergades slow with acclimation (PBT)







-------
Abamectin
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 377 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Abamectin
61779
71751412
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.002









1.5
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1997









2001
Critical Effect





Embryo- and fetotoxicity: increased mortality, reduced
weight. Maternal toxicity: reduced body weight gain









Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
9 3 Li
HRL Ratio(s)
NC HRL/SWC EEC: 57.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rat study; HBPTO Handbook of pesticide toxico ogy. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year2,1160,2001
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Abamectin
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 378 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total


# Sam pies
Amount
Released
14,932
9
9.3


#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr


% Samples with
detects
Number of
States
24
1
2


Minimum value of
Detects
Units
States
States
States


Maximum
value of
Detects
Year
1997
2004
2004


Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 0.244 ug/L
Non-cancer: 57.4
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Ground water chronic: 0.00371 ug/L
Cancer:







Pesticide; anthelm ntic (HSDB)
Value

5,000


1.70E-07


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (HSDB)







-------
Acetaminophen
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 379 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Acetaminophen
4349
103902
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
EMEAADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.05





747




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect





Cholestatic effects





Liver - other changes, Kidney, Ureter, Bladder - changes
in bladder weight, Nutritional and Gross Metabolic - weight
oss or decreased weight gain




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification



495

3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
mg/kg-d














Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


350

Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude ,,, _
10 5 NL'
HRL Ratio(s)
NC HRL/NREC SW MAX: 35
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; The European Union European Medicines Agency (EIVIEA)
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-394,1992
Supplemental Data







Tumorigenic Dose - 50



DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetaminophen
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 380 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, etal., 2007
Focazio, etal., 2008

HRL Ratios (HRL/NREC SW MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

84



Amount
Released


# PWSs/Sites/
Samples








Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




23.8



Number of
States


% PWSs/Sites/
Samples with
detects
0







Units
States
States
States
Minimum value of
Detects
Not detected


Non-cancer: 35
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




10



Year


Maximum
value of
Detects
Not detected
0.16


0.11













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
Not detected


90% of
Detects
Not detected


Units for Mag
data

ug/L
Notes
Drinking water monitoring; Snyder, et al., 2007. Removal of EDCs and
Pharmaceuticals in Drinking and Reuse Treatment Processes. American
Water Works Association.
Focazio, etal., 2008. Sci.Tot. Env., 402(2-3), pp. 201-216.

Cancer:







Pharmaceutical
Value
15
41
0.46

6.42E-13
14,000
38
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow







-------
Acetic acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 381 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetic acid
2464
64197
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1.47



3,310
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1972



1959
Critical Effect











Gastrointestinal - changes in structure orfunction of
esophagus, Gastrointestinal - ulceration or bleeding
from small intestine, Gastrointestinal - ulceration or
bleeding from large intestine



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AIHAAP American Industrial Hygiene Association Journal.
(AIHA,475Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year
33,624,1972. Human study
Supplemental Data


rat study; DMDJAP Delaware State Medical Journal. (Wilmington, DE) V.1-32(1), 1929-60. For
publisher information, see DSMJAA. Volume(issue)/page/year 31,276,1959
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3.43

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetic acid
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 382 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; veterinary medicine; chemical reagent (HSDB)
Value

6.5-228
-0.71


1,000,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Acetic anhydride
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 383 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetic anhydride
4676
108247
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,780
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1951
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
10 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10,
1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year4,119,1951; rat study
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetic anhydride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 384 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; chemica reagent (HSDB)
Value
4.4 minutes




120,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Acetone
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 385 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetone
2510
67641
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.9

0.9
2





100
3,000




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2003

2003
1994











Critical Effect

Nephrotoxicity

Nephropathy
Hemato.






Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Blood - normocytic anemia




Prevalence Magnitude
9 7 Li
HRL Ratio(s)
NC HRL/NAWQA 90% : 568
Notes
Reference Dose
Reference Dose; rat study; UF = 1000, MF = 1; Dietz, et., al, 1991; NTP, 1991
Reference Dose
Reference Dose
Minimal Risk Level, UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NIH-91-3122
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1






1990













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



6,300

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetone
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 386 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,605
# Sam pies


Amount
Released



# PWSs/Sites/
Samples
653

168
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
25

6.45
% Samples with
detects


Number of
States



% PWSs/Sites/
Sam pies with
detects
3.83

0.3
Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
2

Non-cancer: 568
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002



1,806
Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
210

2.77
Median value of
Detects


11.1
90% of
Detects


52.4
99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
11

90% of
Detects
114

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Solvent; in PPCPs (HSDB)
Value

1.98
-0.24

3.96E-05
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Acetone cyanohydrin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 387 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetone cyanohydrin
2688
75865
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.0008







14.8



1.90
Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1994







1971



1994
Critical Effect



increased relative weight; liver







Gastrointestinal - ulceration or bleeding from stomach,
Liver - other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
4 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; UF = 3,000; Rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 35-wk rat study; AMPMAR Archives des Maladies
Professionnelles de Medecine du Travail etde Securite Sociale. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.7- 1946- Volume(issue)/page/year 32,653,1971
Supplemental Data


Mouse study; TOVEFN Toksikologicheskii Vestn k. (18-20 Vadkovskii per. Moscow, 101479, Russia)
History Unknown Volume(issue)/page/year (1), 29,1994
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



5.6

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetone cyanohydrin
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 388 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
106,961
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
4
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; (HSDB)
Value

1
-0.03

1.30E-05
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
Acetonitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 389 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acetonitrile
2621
75058
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.006












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



Blood- decreased hematocrit; Liver- increased relative
weight; hepatic lesions; erythrocyes- decreased cell
count












Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

42

Y/N
Y/N

ug/L
ug/L






Teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acetonitrile
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 390 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

11,220
12,784,367
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

14
30
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; in PPCPs; chemical intermediate (HSDB)
Value

4.5
-0.34

3.45E-05
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
Acrylic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 391 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acrylic acid
2862
79107
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.5

0.5


0.135




250




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1994









1983




Critical Effect

Reduced pup weight




iver




Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in bladder weight, Related to Chronic Data - changes in
testicular weight




Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose. BASF, 1993. Rat study
Reference Dose
BASF, 1993. rat study, uf=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270
Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year 6,1,1983; oral study in rat
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999











Vol. 19, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3,500

Y/N
Y/N

ug/L
ug/L






Teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Acrylic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 392 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

19,798
6,817,569
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

9
30
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical and polymer intermediate (HSDB)
Value

1.201
0.35

3.69E-07
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF/BST






Notes
BF = Biodegrades fast (BIODEG); BST = Biodegrades somet mes/recalcitrant (BIODEG)







-------
Acrylonitrile
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 393 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Acrylonitrile
4592
107131
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.001
0.04






2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




1990






1984




Critical Effect



decreased sperm counts
Hemato.; decreased red cell counts






Endocrine - adrenal cortex hyperplasia, Endocrine -
changes in adrenal weight, Blood - other changes




Prevalence Magnitude
1 1
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Leve ; Biodynamics, 1980b. Rat study; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons
Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year
4, 1 31 , 1 984; 60-day rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.006
0.54
1

B1
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1






1990
1999










Biodynamics, 1980a,b; Quastetal., 1980a; rat study
OEHHA lists IARC classification of 2B
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

7
0.06
Y/N
Y/N

ug/L
ug/L






Teratogen list



EPA, RAISHE, OEHHA, IARC, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
      Acrylonitrile
      CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 394 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,614


# Sam pies
Amount
Released

21,559
7,925,644
# PWSs/Sites/
Samples
180

0


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0

0


% Samples with
detects
Number of
States

10
29
% PWSs/Sites/
Samples with
detects
0

Not Detected


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
> 1B
> 1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected


Maximum value
of Detects
Year
1997
2004
2004
Maximum value
of Detects
Not Detected

Not Detected


Median value of
Detects
Not Detected


90% of Detects
Not Detected


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Pesticide/fumigant; polymer intermediate (HSDB)
Value

8.3
0.25

0.000138
74,500

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Adipic acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 395 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Adipic acid
5549
124049
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











4,000
800



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date











1967




Critical Effect











gastrointestinal effects: hypermotility, diarrhea and weight
ow or decreased we ght gain
Chronic inflamatory alterations of the intestines



Prevalence Magnitude ,,, ,,, _
10 5 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAO Nutrition Meeting Reports 401 1 1 967
Supplemental Data; FDA/Informatics. NTIS PB230 305



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,867

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Adipic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 396 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; in PPCPs; polymer intermediate (HSDB)
Value

26
0.08

4.70E-12
14,000-30,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Adiponitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 397 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Adiponitrile
4964
111693
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










30


22

22
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1986


1996

1984
Critical Effect










Maternal toxicity




Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data. Journal. Johannsen et al 1986
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Sax's Dangerous Properties of Industr al Materials. 9th ed. Volumes 1-3. New York, NY: Van
Nostrand Reinhold, 1996., p. 73. Rabbit study.

rabbit study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
49(12), 40,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1






1991













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Adiponitrile
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 398 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical and polymer intermediate (HSDB)
Value

16
-0.32

1.21E-09
80,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Aldrin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 399 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aldrin
6511
309002
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00003
0.00003
0.00003
0.00003
0.0001

0.0001



0.05




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
1992

2000
1994

2000



1966




Critical Effect

iver lesions, increased liver to body weight ratio


iver


iver



Endocrine - other changes, Blood - other changes




Prevalence Magnitude , „
1 6 L'
HRL Ratio(s)
CAR HRL/NCOD R2 90% : 4.55
Notes
Reference Dose
Reference Dose; Fitzhugh et al., 1964; Basis LOAEL 0.025, rat, UF=1000.
Reference Dose
Reference Dose
Minimal Risk Level; Fitzhugh et a ., 1964; Basis LOAEL 0.025; rat study; UF = 1,000
Acceptable Daily Intake; combined total for aldrin and dieldrin
Acceptable Daily Intake
Tolerable Daily Intake; Fitzhugh and Nelson, 1963; Fitzhugh etal., 1964; Basis LOAEL 0.025; rat study,
dog study; UF = 250
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year31(4),13,1966; 26-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
17
17

B2
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1


1992



1992
1987











Vol. 5, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.21
0.002
Y/N
Y/N

ug/L
ug/L






Teratogen



EPA, RAISHE, OEHHA, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Aldrin
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 400 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


12,221



12



0.0982



0.1



4.4



0.84



4.4



4.4

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP

HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released

0
2,961
# PWSs/Sites/
Samples
5,226
105




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
32





% Samples with
detects


Number of
States

1
4
% PWSs/Sites/
Sam pies with
detects
0.61





Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.01


Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
107





Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
99


90% of
Detects
102


Units for Mag
data
ug/L
ug/L

Cancer: 4.55



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
2002





Former insecticide (HSDB)
Value

106,000
6.5

4.40E-05
0.017

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (HSDB)







-------
alpha-Chlorohydrin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 401 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Chlorohydrin
3823
96242
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











10
5


26
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date











2000
1994


1982
Critical Effect











Reproductive - Paternal Effects - spermatogenesis (incl.
genetic material, sperm morphology, motility, and count),
Reproductive - Fertility - other measures of fertility
Reproductive - Paternal Effects (sperm motility and
count)


Behavioral - somnolence (general depressed activity),
Nutritional and Gross Metabolic - weight loss or decreased
weight gain
Prevalence Magnitude , „
5 7 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; rat study. REPTED Reproductive Toxicology. (Pergamon Press
nc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year
15,11,2000
Supplemental Data; Reproductive Toxicology Volume 8, Issue 3, May^June 1994, Pages 237-250


rat study; IPCLBZ International Pest Control. (McDonald Pub., 238A High St., Uxbridge, Middx., UK) V.5-
1962- Volume(issue)/page/year 24,20,1982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



11.7

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   alpha-Chlorohydrin
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 402 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; chemical intermediate (HSDB)
Value
1 5 days
1


6.10E-08
1,000,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
alpha-Methylbenzenemethanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 403 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Methylbenzenemethanol
3990
98851
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










375
1,071




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1990
1990




Critical Effect










Decreased body weight gain, impaierd renal function,
early mortality CancerPositive male rat and female
mouse, negative female rat and male mouse
Liver - changes in liver weight, Related to Chronic Data -
death




Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue);pagefyear NTP-TR-369,1990
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-369,1990; 13-wk rat
study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,625

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   alpha-Methylbenzenemethanol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 404 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B

Units
Ibs/yr
Ibs/yr
Year
1994
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flavoring agent; n PPCPs; laboratory reagent (HSDB)
Value

<5-52


2.90E-07
1,950
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
alpha-Methylstyrene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 405 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
alpha-Methylstyrene
3989
98839
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



o.or





1,000

50



4,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1987







1990



1963
Critical Effect



increased weight, liver





reproductive/developmental

Kidney, Ureter, Bladder - proteinuria, Blood - changes in
eukocyte (WBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; rat study; UF = 1 ,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGH "Vrednie chemichescie veshestva, galogenproisvodnie
uglevodorodov". (Hazardous substances Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.
Volume(issue)/page/year -,203,1990; 4-wk rat study
Supplemental Data


mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
28(12), 14,1963
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



490

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   alpha-Methylstyrene
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 406 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC> Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Polymer intermec
Value

817.2
3.48

0.00254
89

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate; UV degradaton inhibitor (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
Ametryn
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 407 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ametryn
9881
834128
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.072
0.009
0.009
0.009







25




Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987
1988
1987







2001




Critical Effect
Liver toxicity. Degenerative & inflam matory liver
effects
iver toxicity

iver







Nutritional and Gross Metabolic - weight loss or decreased
weight gain; Blood - other changes




Prevalence Magnitude ,,, _
6 6 NL'
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose; Supplemental Data; OPP. Ciba-Geigy, 1961a
Reference Dose; Ciba-Geigy, 1961 a. rat study; Basis NOEL 8.6 mg/kg-d; UF = 1,000
Reference Dose
Reference Dose; Ciba-Geigy, 1961 a. rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake

No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; HBPTO Handbook of pesticide toxicology. Robert Krieger ed,
Academic press, 2001 Volume(issue)/page/year 2,1 51 4,2001 ; 2-yr rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



504

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ametryn
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 408 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released
445,571
31
409
# PWSs/Sites/
Samples
75



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects


Number of
States
5
3
5
% PWSs/Sites/
Samples with
detects
0



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
Not Detected



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Herbicide (HSDB)
Value

445
2.98

2.39E-09
209

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (HSDB)







-------
Amitraz
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 409 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Amitraz
32124
3308961 1
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0125
0.0025

0.0025

0.01









100
Units
mg(kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1998



1998









1978
Critical Effect
Hypothermia, drowsiness, decreased blood pressure &
heart rate
blood sugar increase, hypothermia

increased mean blood sugar concentration











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, _
9 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Upjohn Co., 1972a; Basis NOEL = 0.25 mg/kg-d; Dog study; UF = 100
Reference Dose
Reference Dose; Upjohn 1973; UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Dog study - SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd.,
College Park, MD 20740) Volume(issue)/page/year 78-1,22,1978
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

87.5

Y/N
Y/N

ug/L
ug/L











CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Amitraz
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 41 Oof 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
137,097
0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
17
0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide; veter nary medication (HSDB)
Value
38
644,000
5.5

9.89E-06
1
7
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Ammonia
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 411 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonia
19125
7664417
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOAEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











6.18
0.9



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/L
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991
2006



Critical Effect











Gastrointestinal - other changes
Taste threshold



Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/DBP ICR MED: 150
Notes
Reference Dose
Reference Dose
Reference Dose

Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; DDSCDJ Digestive Diseases and Sciences. (Plenum Pub. Corp.,
233 Spring St., New York, NY 1001 3) V.24- 1979- Volume(issue)/page/year 36,33,1991; 4-wk rat study
Lowest Observed Effect Level. EPA: 2006 Edition of the Drinking Water Standards and Health
Advisories. EPA 822-R-06-01 3. Note: Taste threshold of 30 mg/L converted to a dose using 2 L/d
drinking water intake and 70 kg body weight.



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1992













Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



30,000

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level
HRL set at taste threshold of 30 mg/L

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Ammonia
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 412 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF IOR



# PWSs/Sites
sampled
68



#with Detects
58



% PWSs/Sites
with detects
85.29



Minimum value of
Detects




Maximum
value of
Detects
1,100



Median value of
Detects
200



Mean value of
Detects
262



Units for Mag
data
ug/L
Ambient Water Occurrence Data
# PWSs/Sites sampled
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1C, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
#with Detects
8,185

# Sam pies


Amount
Released

6,284,889
172,424,459
n
PWSs/Sites/Sa
mples
535

% PWSs/Sites
with detects
5,907

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
171

Minimum value
of Detects
72.2

% Samples with
detects


Number of
States

50
54
%
PWSs/Sites/Sam
pies with
detects
32

Maximum value of
Detects
2

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
10

Non-cancer: 150
Amount Range
>10M-50M
>500M - 1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Median value
of Detects
34,000

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
15,000

90% of Detects
43

Median value of
Detects


99% of
Detects
284

90% of
Detects


Units for Mag
data
2,400

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L

Notes




Notes



ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L


Measured as N
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
231

99% of
Detects
1,291

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermediate; defoliant; antifungal agent for produce (HSDB)
Value

14.3
-1.38

3.45E-06
3,740

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Ammonium carbamate
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 413 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonium carbamate
10601
1111780
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















681
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea, Skin and
Appendages - hair
Prevalence Magnitude , „
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issueXpage;yearOTSOS35595; rat study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ammonium carbamate
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 414 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in fertilizers (HSDB)
Value
1 5 days

-3.67


very soluble
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Ammonium thiosulfate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 415 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ammonium thiosulfate
19349
7783188
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,098
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1982
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7
ncomplete data for scoring HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 1 13095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 26(6),54,1982. Guinea pig study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Ammonium thiosulfate
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 416 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50-100M
>50-1QOM
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide; defoliant; in PPCPs (HSDB)
Value





very soluble

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Aniline hydrochloride
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 417 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aniline hydrochloride
6119
142041
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1 NOTE: SK 61 19 s the salt of ani ine (SK 2438)
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











20




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1993




Critical Effect











Endocrine - changes in spleen weight, Blood -
methemoglobinemia-carboxyhemoglobin, Blood -
changes in erythrocyte (RBC) count




Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; AECTCV Archives of Environmental Contam ination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issue)/page;year 24,368,1993. 90-day rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

46.7

Y/N
Y/N

ug/L
ug/L






Teratogen list



CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Aniline hydrochloride
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 418 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1990
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer and chemcal intermediate; in PPCPs, in inks (HSDB)
Value
1 5 days
44-489
0.9

2.02E-06
36,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)
Environmental fate parameters are for the free base, not the hydrochloride salt.






-------
Anisole
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 419 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Anisole
4127
100663
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.65



2,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994



1946
Critical Effect











Endocrine - other changes



Behavioral - tremor, Behavioral - convulsions or effect on
seizure threshold, Behavioral - excitement
Prevalence Magnitude ,,, _
3 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVQK "Vrednie chemichescie veshestva, galogen I
kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen
containing substances), Bandman A.L. et al., Chimia, 1994. Volume(issue)/page7year -,290,1994. 26-
wk rabbit study
Supplemental Data


mouse study; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins
Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 88,400,1946
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.517

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Anisole
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 420 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Flavoring agent; n PPCPs; chem cal intermediate (HSDB)
Value

35
2.11

0.00435
1,520
31
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Aspirin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 421 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Aspirin
2149
50782
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.0021
66.7


200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2002



1969
Critical Effect











Lungs, Thorax, or Respiration -tumors



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
1 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BJCAAI British Journal of Cancer. (Macmillan Press Ltd.,
Houndmills, Basingstoke, Hants. RQ21 2XS, UK) V.1- 1947- Volume(issue)/page/year 87,49,2002.
24-wk female human study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)


rat study; 34ZIAG "Toxicology of Drugs and Chemcals," Deichmann, W.B., New York, Academic Press,
nc., 1969 Volume(issue)/page/year-,67,1969
Cancer Data - no quantitative risk estimate for the cancer effect was identified
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.005

Y/N
Y/N

ug/L
ug/L






Teratogen list




CACART, UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Aspirin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 422 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Medication (HSDB)
Value
5.4-6.3 days
42-106
1.19

1.30E-09
4,600
33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Auramine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 423 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Auramine
7200
492808
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.168




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1974




Critical Effect











Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme
inhibition, induction, or change in blood or tissue
levels - catalases




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad,
Russia) V.1-145, 1949-82. Discontinued. Volume(issue)/page/year 105,45,1974. 17-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.88


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1987











Vol. 1, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


0.392

Y/N
Y/N

ug/L
ug/L










OEHHA, CACART, IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Auramine
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 424 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n dye manufacture; medication; fungicide; antiseptic (HSDB)
Value
65-74 days
2,000
3.5

8.05E-08


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DST






Notes
Degrades sometimes/recalcitrant (HSDB)







-------
Azinphos-methyl
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 425 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Azinphos-methyl
3200
86500
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00149




0.005





0.91




Units
mgflsg
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1991





1997




Critical Effect
RBC ChE inhibition, increased incidence of diarrhea










Brain and Coverings - other degeneratve changes, Blood -
other changes, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - true cholinesterase




Prevalence Magnitude
8 3 NLi
HRL Ratio(s)
NC HRL/NAWQA 90% : 68.9
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FAATDF Fundamental and Applied Toxicology. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, seeTOSCF2
Volume(issue)/page/year35,101,1997; 1 3-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC

Y

10.4

0.2
Y/N
Y/N

ug/L
ug/L
mg/L













UMD
Drinking Water Equivalent Level


Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
Azinphos-methyl
                                                                                          EPA-OGWDW
August 2009
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,103

# Sam pies
Amount
Released
2,091,014


# PWSs/Sites/
Samples
283
669


12
145

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
# of detects


8
5
0
2.04

% Samples with
detects
Number of
States
42


% PWSs/Sites/
Samples with
detects


2.5
2.2
0
0.002

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.012
0.012



Non-cancer: 68.9
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



3.37

Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.021
0.253
0.144
0.114

0.027

Median value of
Detects
0.151

90% of
Detects
0.932

99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
National Aggragate
Notes



Median value of
Detects





95th % lie
value of
Detects





Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) raw water data
Pesticide Pilot Mentoring Program (USGS/EPA) finished water data
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Insecticide (HSDB)
Value
27.9 days
487-4,644
2.75

2.40E-08
20.9

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DS






Notes
DS = Degrades slow (HSDB)







-------
Bentazon
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 427 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bentazon
28242
25057890
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.03
0.03
0.03

0.1










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1998
1999
1989

1998










Critical Effect

Blood loss into the gastrointestinal tract; Coagulation
defect in male & female dogs, Circu atory system .

blood loss in gastrointestinall tract; coagulation defect












Prevalence Magnitude ,,, _
9 4 NL'
HRL Ratio(s)
NC HRL/NAWQA 90% : 276
Notes
Reference Dose
Reference Dose; Allen et al., 1 989. Dog study; UF = 100, Basis NOAEL 3.2 mg/kg-d
Reference Dose
Reference Dose; UF = 100; dog study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




E

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1






1998













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHO DWQ



210

300
Y/N
Y/N

ug/L
ug/L
ug/L














Drinking Water Equivalent Level


World Health Organization Drink ng Water Guide
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
Bentazon
                                                                                         EPA-OGWDW
                                                                                                                                                                                 August 2009
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP

CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,540

# Sam pies


Amount
Released
7,749,130


# PWSs/Sites/
Samples
100
186


n
PWSs/Sites/Sa
mples
5,583
197

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
# of detects
1
14
80
21
n of detects
2
4.339

% Samples with
detects


Number of
States
45


% PWSs/Sites/
Samples with
detects
1
7.5
25.6
9.3
%
PWSs/Sites/Sam
pies with
detects
0.04
0.002

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.0188
0.002


Minimum value of
Detects
0.23
Non-cancer: 276
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



11.5

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
0.0188
0.018
0.344
0.019
Maximum
value of
Detects
6.2
0.1

Median value of
Detects


0.76

90% of
Detects


4.79

99% of Detects


Units for Mag No(es
data

ug/L
ug/L
ug/L


ug/L
ug/L National Reconnaissance
ug/L National Reconnaissance
Units for Mag No(es
data
ug/L National Aggregate
ug/L National Aggregate
Notes



Median value of
Detects




Median value of
Detects
3.11
95th % lie
value of
Detects


0.021
0.019
90th % lie
value of
Detects
5.58
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2002
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) raw water
Pesticide Pilot Mentoring Program (USGS/EPA) finished water

Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Former herbicide (HSDB)
Value
6.7-50 days
37.5
2.34

2.18E-09
500

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (HSDB)







-------
Benzaldehyde
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 429 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzaldehyde
4114
100527
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1







17.1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1994




Critical Effect

Forestomach hyperplasia & lesions, kidney toxicity
renal tubular necrosis). Gl tract, Kidney

forestomach, kidney; lesions, toxicity







Lungs, Thorax, or Respiration - other changes, Liver -
multiple effects




Prevalence Magnitude .,, „
6 7 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Kluwe et al., 1 983; rat study; UF = 1 ,000; Basis NOEL 200 mg/kg-d
Reference Dose
Reference Dose; rat study; Kluwe, 1983; UF = 1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Sandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,396,1994; 5-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Benzaldehyde
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 430 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Former pesticide; chemical intermediate (HSDB)
Value

32.7
1.48

2.67E-05
6,570

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Benzidine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 431 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzidine
3586
92875
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.003

0.003








2.7



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect

brain, liver

brain, liver; cell vacuo izations, call alterations












Prevalence Magnitude , „
3 1 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Littlefield etal., 1983; mouse study
Reference Dose
Reference Dose; Littlefield etal., 1983; mouse study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.00002
230
500

A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1987






IRIS




Vol. 29, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


21
0.0002
Y/N
Y/N

ug/L
ug/L










EPA; RAIS; OEHHA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Benzidine
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 432 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

66.61
82.92
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

1
3
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye manufacture; chemical intermediate (HSDB)
Value

2,740
1.34

7.05E-11
322

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Benzofuran
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 433 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzofuran
6383
271896
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












30



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1989



Critical Effect












Nephropathy (males) chronic inflamation, ulcers and
epitheliam hyperplasia of the stomach Clear evicence
of cancer in male and female mice, some evidence in
female rats, no evidence in male rats



Prevalence Magnitude
1 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 3-wk rat study
Supplemental Data; NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/pagefyear NTP-TR-370,1 989



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1995











Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70

Y/N
Y/N

ug/L
ug/L










IARC, CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Benzofuran
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 434 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n resin manufacture (HSDB)
Value
1 5 days
680
2.67

0.00053

24
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Benzoic acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 435 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzoic acid
2484
65850
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

4

4












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect

No adverse effects observed. Decreased Potency
Score by one integer














Prevalence Magnitude ,,,
87 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; FDA, 1973; human study; Basis NOAEL 34 mg/kg-d; UF = 1
Reference Dose
Reference Dose; FDA, 1973; human study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1






1989













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



28,000

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
    Benzoic acid
    CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 436 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
FRI Release - surface water
FRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,E, Half life
Koc, Organic Carbon Partition Coefficient
og Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1DOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; food preservative; chemical intermediate (HSDB)
Value
0.2-3.6 days
14.49
1.87

3.82E-08
3,400

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Benzotriazole
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 437 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzotriazole
3739
95147
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.599




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1981




Critical Effect











Endocrine - other changes, Blood - normocytic
anemia, Blood - leukopenia




Prevalence Magnitude
57 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(1 1 ),70,1 981 ; 26-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.4

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Benzotriazole
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 438 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Photographic chemical; chemical ntermediate; plastics stabilizer; corrosion nhibitor (HSDB)
Value

145
1.44

3.17E-07
19,800
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (BIODEG)







-------
Benzotrichloride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 439 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzotrichloride
3933
98077
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.03




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect











Liver - other changes, Liver - changes n liver weight,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - hepatic microsomal mixed oxidase
(dealkylation, hydroxylation, etc.)




Prevalence Magnitude
42 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Sandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,43,1994; 28-day rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0003
13


B2

mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1






1990





ung

IRIS





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


0.07
0.003
Y/N
Y/N

ug/L
ug/L










CACART; EPA; RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Benzotrichloride
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 440 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
745
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
4
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

1,180
3.9

0.000259
21.7
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Benzyl alcohol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 441 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Benzyl alcohol
4113
100516
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.3







143
5



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1989




Critical Effect



Epithelial hyperplasia, forestomach







Brain and Coverings - other degeneratve changes,
Related to Chronic Data - death




Prevalence Magnitude .,, „
6 7 NLi~Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NTP, 1988. rat study; UF = 1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-343,1989; 13-wk rat
study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,100

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Benzyl alcohol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 442 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value

15.7
1.1

3.38E-07
42,900

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast(BIODEG)







-------
Bis(2-chloro-1-methylethyl) eth
CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 443 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-ch loro-1 -m ethylethyl) ether
4702
108601
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
2 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











12.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1985




Critical Effect











Blood - changes in leukocyte (WBC) count, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
Enzymes





3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 50(5), 69,1985; 26-wk rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

o.or


c
3
mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)"1







1999











Vol. 41, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


30.1
0.5
Y/N
Y/N

ug/L
ug/L










CACART; RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bis(2-chloro-1-methylethyl) eth
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 444 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
883
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent; medication (HSDB)
Value

39.2
2.48

0.000113
1,700

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Bis(2-chloroethyl) ether
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 445 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-chloroethyl) ether
4939
111444
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











26
25



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994
1981



Critical Effect











Brain and Coverings - other degeneratve changes, Liver -
multiple effects, Kidney, Ureter, Bladder - other changes
Decreased body weight



Prevalence Magnitude
4 2 Li
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGK Vrednie chemichescie veshestva, galogen I kislorod
sodergashie organicheskie soed nenia". (Hazardous substances. Galogen and oxygen containing
substances), Bandman A.L. et a ., Chimia, 1994. Volume(issue)/page/year -,283,1994; 45 day oral study
n rat
ATSDR; Weisburger, etal., 1981. Journal of the National Cancer Institute, 67: 75-88.



Cancer Data
EPA Lifetime Cancer Risk, 104
ATSDR Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.003
0.3
1.1
2.5

B2
3
mg/L
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1988
1999







IRIS
ATSDR




Vol. 9, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


60.67
0.03
Y/N
Y/N

ug/L
ug/L










EPA; RAISHE; OEHHA; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Bis(2-chloroethyl) ether
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                               EPA-OGWDW
    August 2009
Page 446 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

2
478
# PWSs/Sites/
Samples
2,348




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0




% Samples with
detects

Number of
States

1
4
% PWSs/Sites/
Samples with
detects
0




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

99% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; chemical intermediate; solvent; gasoline additive (HSDB)
Value

14.95
1.29

1.70E-05
17,200

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA/BS/BST






Notes
BFA = Biodegrades fast with acclimat on; BS = Biodegrades slow; BST = B odegrades sometimes/recalcitrant (BIODEG)







-------
Bis(2-ethylhexyl) sodium sulfos
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 447 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(2-ethylhexyl) sodium sulfosuccinate
8032
577117
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.5
5


1,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1943



1962
Critical Effect











Behavioral -food intake (animal), Gastrointestinal -
hypermotility, diarrhea, Related to Chronic Data - death



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 3 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JIHTAB Journal of Industrial Hygiene and Toxicology.
(Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year 25,175,1943; 24 wk rabbit study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)


Rat study; JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1 995
Broadway, Suite 1701, New York, NY 10023) V.1- 1947- Volume(issue)/page/year 13,469,1962
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.17

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bis(2-ethylhexyl) sodium sulfos
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 448 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L



ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; in PPCPs; medical on (HSDB)
Value

9.37-1,041


5.00E-12
71,000
22
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Bis(chloromethyl) ether
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 449 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bis(chloromethyl) ether
7727
542881
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude , „
1 1 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.000016
220
46

A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1991
1987




ung

IRIS




Vol. 4, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.00016
Y/N
Y/N

ug/L
ug/L










EPA; RAISHE; OEHHA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bis(chloromethyl) ether
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 450 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Laboratory reagent; in polymer manufacture (HSDB)
Value

4.395
0.58

0.000206
22,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Bisphenol A
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 451 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bisphenol A (4,4'-lsopropylidenediphenol)
2918
80057
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.05

0.05







2.5




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect

Reduced body weight














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

350

Y/N
Y/N

ug/L
ug/L










Prevalence Magnitude
10 5 NLi
HRL Ratio(s)
NC HRL/NREC NA SW MED: 1,750
Notes
Reference Dose
Reference Dose; Basis = LOAEL 50 mgflsg-d; UF = 1,000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat
Supplemental Data











UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bisphenol A
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 452 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Kolpin, etal.,2002
Stackelberg, etal., 2007
Stackelberg, etal., 2007
Focazio, etal., 2008
HRL Ratios (HRL/NREC NA SW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

85
# Sam pies


Amount
Released

3,538
1,504,711
# PWSs/Sites/
Samples



73

35
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



7

41.2
% Samples with
detects
21.07
10.78
Number of
States

8
27
% PWSs/Sites/
Samples with
detects
41.2
17
67
9.6

Minimum value of
Detects


Units
States
States
States
Maximum value of
Detects
12
0.22
0.36
1.9
Non-cancer: 1,750
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002

Maximum
value of
Detects


Year

2004
2004
Units for Mag
data
ug/L
ug/L
ug/L
ug/L

0.14
Median value of 90% of „„„, . „ . .
99% of Detects
Detects Detects
0.2
0.2
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Notes
Surface water monitoring; Kolpin, eta., 2002. Env. Sci. &Technol., 36(6), pp. 1202-1211.
New Jersey Finished Drinking Water; Stackelberg, etal., 2007. Sci. Tot. Environ., 377(2-3), pp. 255-272.
New Jersey Surface Water; Stackelberg, et al., 2007. Sci. Tot. Environ., 377(2-3), pp. 255-272.
NREC II Raw Drinking Water; Focazio, et al., 2008. Sci.Tot. Env., 402(2-3), pp. 201-216.
Cancer:




Production of polycarbonate and epoxy resins. Formely used as fungicide. (HSDB)
Value

75,200
3.32

9.2E-12
120

Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA-BST






Notes
BFA = Biodegrades fast with acclimat on; BST = Biodegrades sometimes/recalcitrant







-------
BMX-1
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 453 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-1 (3-Chloro-4-(bromochloromethyl)-5-
hydroxy-2(5H)-furanone)
78954
132059519
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification





HM
mg/L
(mg/kg-d)-1
(mg/kg-d)"1















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 1
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; HM = High to medium probability of be ng carcinogenic

DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   BMX-1
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 454 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



# PWSs/Sites/
Samples






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States



% PWSs/Sites/
Samples with
detects
44





Units
States
States
States
Minimum value of
Detects


Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects
0.17













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.01

90% of
Detects


Units for Mag
data
ug/L

Cancer:



Notes
Finished drinking water monitoring; Krasner, era./, 2006. Env. Sci.
Technol. , 40(23), pp 7175-7185 (and related documentation).





Disinfection By-Product
Value







Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
BMX-2
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 455 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-2 (3-Chloro-4-(dibromomethyl)-5-hydroxy-
2(5H)-furanone
74966
132059520
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification





HM
mg/L
(mg/kg-d)"1
(mg/kg-d)"1















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 1
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; HM = High to medium probability of be ng carcinogenic

DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   BMX-2
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 456 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



# PWSs/Sites/
Samples





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States



% PWSs/Sites/
Sam pies with
detects
33




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects
0.03












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
ND
90% of
Detects

Units for Mag
data
ug/L
Cancer:



Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci.
Technol., 40(23), pp 7175-7185 (and related documentation).




Disinfection By-Product
Value







Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
BMX-3
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 457 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
BMX-3 (3-Bromo-4-(dibromomethyl)-5-hydroxy-
2(5H)-furanone
78951
132059531
Attribute Scores
Potency Severity

Prevalence Magnitude
10 1
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification





HM
mg/L
(mg/kg-d)-1
(mg/kg-d)-1















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N
mg/L
ug/L
ug/L










3-model Categorical Prediction

HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; HM = High to medium probability of be ng carcinogenic

DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   BMX-3
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 458 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., 2006
HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


# PWSs/Sites/
Samples





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States


% PWSs/Sites/
Samples with
detects
11




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
0.4












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
ND
90% of
Detects

Units for Mag
data
ug/L
Cancer:



Notes
Finished drinking water monitoring; Krasner, et al., 2006. Env. Sci.
Technol., 40(23), pp 7175-7185 (and related documentation).




Disinfection By-Product
Value







Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Boron
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 459 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Boron
18864
7440428
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.2
0.09
0.09
0.01






31




Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




1992






1970




Critical Effect

Decreased fetal weight (developmental)

Atrophy and spermatigenetic arrest







Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - dehydrogenases, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
transferases




Prevalence Magnitude
10 10
HRL Ratio(s)
NCHRL/NIRS90%:2.95
Notes
Reference Dose
Reference Dose; Price etal., 1996a; Heindel etal., 1992
Reference Dose
Reference Dose; Basis = NOAEL/LEL, MF = 1, UF= 100, dog, testicle (Weir & Fisher, 1972)
Minimal Risk Level - Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rabbit; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(1 1 ) , 1 1 , 1 970
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ
CADW MAC


3
1,400

0.5
5
Y/N
Y/N
mg/L
ug/L
ug/L
mg/L
mg/L






1992









Drinking Water Equivalent Level


World Health Organization Drink ng Water Guide
Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Boron
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 460 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



810



81.9



5



3,950



46.8



475



2,585
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released



# PWSs/Sites/
Samples
9,360



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4,841



% Samples with
detects
Number of
States



% PWSs/Sites/
Sam pies with
detects
51.7



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.01

Non-cancer: 2.95
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
800,800



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
180

90% of
Detects
730

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; oxygen scavenger; catalyst; in composite structural mater als (HSDB)
Value

14.3
0.23

0.0245
43,700

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
Bromacil
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 461 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromacil
6526
314409
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.1

0.1








62.5




Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1970




Critical Effect
Decreased body weight gain










Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
NC HRL/NAWQA 90% : 206
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(1 1 ) , 1 1 , 1 970
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




C

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y
5
700

Y/N
Y/N
mg/L
ug/L
ug/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Bromacil
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 462 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP

CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,555

# Sam pies

Amount
Released
614,219
0
0
# PWSs/Sites/
Samples
100
197


# PWSs/Sites/
Samples
7,392
108

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
2
49
#with Detects
3
2.37

% Samples with
detects
15.2
0.61
Number of
States
4
0
0
% PWSs/Sites/
Sam pies with
detects
0
0
0.9
15.7
% PWSs/Sites/
Samples with
detects
0.04
0.001

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects




Minimum value of
Detects
0.93
Non-cancer: 206
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



57

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


0.481
0.481
Maximum
value of
Detects
4
0.245

Median value of
Detects
0.675
0.57
3.4

90% of
Detects

25.9

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




Median value of
Detects
1.5
95% of
Detects



0.081
90% of
Detects
3.18
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) finished water data
Pesticide Pilot Mentoring Program (USGS/EPA) ambient water data
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Herbicide (HSDB)
Value
64-275 days
2.3-289
2.11

1.29E-10
815

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Bromine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 463 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromine
19194
7726956
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















440
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issueXpage/year 39(4),86,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Bromine
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 464 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

5
381,257
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

1
15
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n water disinfect on; flame retardant; chemical intermediate; in dyes; med cation (HSDB)
Value





33,600

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Bromobenzene
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 465 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromobenzene
4724
108861
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.02












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



Liver lesions












3-model Categorical Prediction
NL?
HRL Ratio(s)
NC HRL/NCOD R1 90%: 21.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Bromobenzene
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 466 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

16,450
24,125


32
31


0.195
0.128


0.04
0.05


40
4.69


1
0.5


6.55
3


40
4.69

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309


# Sam pies


Amount
Released



# PWSs/Sites/
Samples
11,878
3


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
0.07


% Samples with
detects


Number of
States



% PWSs/Sites/
Samples with
detects
0.03
0.009


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.5

Non-cancer: 21.4
Amount Range
>500K-1M
>500K-1M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.4


Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
83
0.012


Median value of
Detects


0.4


90% of
Detects


0.4


99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.74
90% of
Detects
66.5
Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





n organic synthesis; as solvent (HSDB)
Value

268
2.99

0.00269
446

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Bromochloroacetonitrile (SCAN)
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 467 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Bromochloroacetonitrile (BCAN)
66739
83463621
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification




3
M
mg/L
(mg/kg-d)"1
(mg/kg-d)"1







1999







Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N
mg/L
ug/L
ug/L










Prevalence Magnitude
10 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; M = Medium probability of being carcinogenic

DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
Bromochloroacetonitrile (SCAN)
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 468 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF ICR finished water




# PWSs/Sites
sampled





#with Detects





% PWSs/Sites
with detects
62.5




Mean value of
Detects
1.63




Maximum
value of
Detects
13.4




Median value of
Detects
1.29




90% of
Detects





99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


# Sam pies





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States


% Samples w/
Detects





Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects













Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes


National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects

95% of
Detects

Units for Mag
data
Notes

Cancer:







Disinfection By-Product
Value
38
13
0.38

1.20E-06
18,700
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze







-------
Bromoethane
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 469 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Bromoethane
2612
74964
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
WHO LD50
Value
















1,350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mgJkg
Date

















Critical Effect
















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
3 7 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



WHO CICAD 42 2002, LD50 1350 mg/kg/day
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

ug/L
ug/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
Bromoethane
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 470 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004

Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent; refrigerant; fumigant; medication (HSDB)
Value
40 days
179
1.61

0.00741
9,000
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DSA






Notes
DSA = Degrades s ow with acclimation







-------
Butanenitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 471 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butanenitrile
4791
109740
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













28


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date













1996


Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude ,
3 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, RJ. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 609


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Butanenitrile
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 472 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
15 days
46
0.53

5.23E-05
33,000
43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Butyl benzyl phthalate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 473 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyl benzyl phthalate
3168
85687
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.2
0.2
0.2



1.3



100




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1989





1998



2000




Critical Effect

Significantly increased liver-to-body weight & liver-to-
brain weight ratios

Significantly increased liver-to-body weight & liver-to-brain
weight ratios







Gastrointestinal - changes in structure or function of
salivary glands, Kidney, Ureter, Bladder - changes in
kidney weight; endocrine - other changes




Prevalence Magnitude
7 3 NL
HRL Ratio(s)
NC HRL/CAL DHS 90%: 23.7
Notes
Reference Dose
Reference Dose; NTP, 1985; Basis NOAEL 159 mg/kg/day, rat, UF=1000, pancreas (NTP, 1985)
Reference Dose
Reference Dose; NTP, 1985; Basis NOAEL/LEL, rat, liver, brain, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis = BMD 132 mg/kd/day, UF = 100, rat (Hammond et al 1987)
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; REPTED Reproductive Toxicology. (Pergamon
Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year
14,513,2000
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1






1988












Vol. 73, 1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


7
1,400

Y/N
Y/N
mg/L
ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Butyl benzyl phthalate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 474 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released



# PWSs/Sites/
Samples
851


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
24


% Samples with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
2.82


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.004

Non-cancer: 23.7
Amount Range
100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
124


Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.2

90% of
Detects
59

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermed ate; plasticizer (HSDB)
Value

9,359
4.73

1.26E-06
2.69

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Butyric acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 475 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyric acid
4649
107926
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













8,790

2,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1982
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
8 5 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Budavari, S. (ed.). 1989. The Merck Index - Encycopedia of Chemicals, Drugs and Biologicals. Rahway,
NJ: Merck and Co., Inc., p. 243.

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1 982
Volume(issue)/page/year -,30,1 982
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Butyric acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 476 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; food additve; varnish manufacture (HSDB)
Value

64
0.79

5.35E-07
60,000
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Butyric anhydride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 477 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Butyric anhydride
4521
106310
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















8,790
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1986
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
8 7 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issueypage/year -,321, 1986; Ratstudy
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Butyric anhydride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 478 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days

1.39

0.000111
4,560
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
C.I. Acid Red 114, disodium sal
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 479 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Acid Red 114, disodium salt
18026
6459945
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










8
120




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991




Critical Effect










Decreased body weight gain shortened lifespan at
higher doses. Clear evidence of carcinogenicity in
male and female rats (mice not tested)
Liver - changes in liver weight, Kidney, Ureter, Bladder -
changes in bladder weight, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
transaminases




Prevalence Magnitude
1 10 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP Report 405
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-TR-
405,1991
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1



















Vol.57, 1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


56

Y/N
Y/N

ug/L
ug/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   C.I. Acid Red 114, disodium sal
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 480 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Textile dye (HSDB)
Value
180

7.86

5.05E-31
2.50E-06
54
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades slow/recalcitrant (PBT)







-------
C.I. Direct Blue 15
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 481 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Direct Blue 15
13296
2429745
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












45



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












22 month study: decreased surviva



Prevalence Magnitude , „
37 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/pagefyear NTP-TR-397,1992



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


105

Y/N
Y/N

ug/L
ug/L










EPA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   C.I. Direct Blue 15
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 482 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
K0c« Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year



Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Notes

ug/L
ug/L
ug/L





ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye; biological stain (HSDB)
Value

136,000,000
0.71

8.56E-44
0.0059

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
C.I. Direct Blue 218
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 483 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Direct Blue 21 8
30455
28407376
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










40
500




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1994
1994




Critical Effect










Squamous and basal hyperplasia of the forestomach -
clear evidence of cancer in male and female mice,
some evidence in male rats and no evidence in female
rats
Liver - other changes, Kidney, Ureter, Bladder - changes
in bladder weight, Blood - pigmented or nucleated red
blood cells




Prevalence Magnitude ,,,
23 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-430,1994
Lowest Observed Adverse Effect Level; oral study in rat; NTPTR National Toxicology Program Technical
Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-
430,1994
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


280

Y/N
Y/N

ug/L
ug/L










CACART; clear evidence of cancer in male and female mice, some evidence in male rats and no
evidence in female rats (NTP)

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   C.I. Direct Blue 218
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 484 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
2,609
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 140
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Textile dye (HSDB)
Value
180





54
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades slow/recalcitrant (PBT)







-------
C.I. Disperse Yellow 3
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 485 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Disperse Yellow 3
13973
2832408
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












400



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1982



Critical Effect












Decreased weight gain throughout the study; a dose
related increase in renal pigmentation was observed in
the females- Cancer was positive for male rats and
female mice and negative for female rats and male
mice



Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTIS National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year NTP-
TR-222,1982



Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1



















Vol. 48, 1990
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



933

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   C.I. Disperse Yellow 3
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 486 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2002
2002
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Textile dye (HSDB)
Value
60

3.98

1.50E-11
1.18
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades slow/recalcitrant (PBT)







-------
C.I. Pigment Red 53, barium sal
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 487 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Pigment Red 53, barium salt (2:1)
16485
5160021
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
5
ncomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












25



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












Haematological effects; spleen, kidney, and liver
effects- unspecified.




3-model Categorical Prediction

HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; SIDS



Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.005


3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1



















Vol.57, 1993
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


58.3

Y/N
Y/N

ug/L
ug/L










CACART; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   C.I. Pigment Red 53, barium sal
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 488 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in paints and inks (HSDB)
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
C.I. Solvent Yellow 14
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 489 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
C.I. Solvent Yellow 14
9896
842079
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












20



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












Cardiac valve fibrosis. Nephropathy, Atrophy of
pancreatic acinus



Prevalence Magnitude ,,, _
1 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; Study Report TR-226



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1



















Vol. 8, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


46.7

Y/N
Y/N

ug/L
ug/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   C.I. Solvent Yellow 14
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 490 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1990







Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye for organic so utions (HSDB)
Value
38

5.51

2.62E-11
0.674
5
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades with acclimation (PBT)







-------
Calcium carbonate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 491 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium carbonate
7087
471341
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











60,000



6,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994



1972
Critical Effect











Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 7 NL
HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.36
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; EPASR United States Environmental Protection Agency,
Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
Washington, DC 20460) History unknown. Volume(issue)/page/year#86940001000,1994
Supplemental Data


28ZPAK"SbornikVysledkuToxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., InstitutPro
Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
Volume(issue)/page/year -, 267, 1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140,000

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Calcium carbonate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 492 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites/
Samples
11,848



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
11,811



% Samples with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
99.7



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
100

Non-cancer: 0.36
Amount Range
>10M-50M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
426,000,000



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
158,000

90% of
Detects
389,000

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Antacid; food additive; pesticide; chemical intermed ate (HSDB)
Value





In sol.

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Calcium hydroxide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 493 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium hydroxide
11051
1305620
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















7,300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date















1981
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 10
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1 -1 1, Yushima, Bunkyo-ku, Tokyo, Japan) V.1-
1950- Volumefissuej/page/year 32,1477,1981
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Calcium hydroxide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 494 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; lubricant; veterinary medication; chemical intermediate (HSDB)
Value





1,730

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/reca citrant







-------
Calcium octadecanoate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 495 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Calcium octadecanoate
11834
1592230
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















10,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgfltg
Date















1992
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No HRL/No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 36(4),17,1992
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Calcium octadecanoate
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 496 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer stabilizer; food additive; waterproofing (HSDB)
Value
38




40
2
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Caprolactam
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 497 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Caprolactam
4466
105602
Attribute Scores
Potency Severity
3 7
Prevalence Magnitude
10 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.5

0.5







482




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988














Critical Effect

Reduced offspring body weight

Reduced offspring body weight







Nutritional and Gross Metabolic - weight loss or decreased
weight gain





3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Serotta etal., 1984
Basis NOAEL 50 mgflsgWay, rat, UF=100
Reference Dose
Reference Dose; Serotta et al., 1984; Basis NOAEL/LOAEL, rat, UF=100, MF = 1
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0555505
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





4
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1



















Vol. 39, Suppl. 7; Vol. 71; 1999
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3,500

Y/N
Y/N

ug/L
ug/L






Teratogen



IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   Caprolactam
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 498 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
KOC. Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n polymer synthes s (HSDB)
Value

57.4
0.66

2.52E-08
772,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Carbaryl
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 499 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbaryl
2448
63252
Attribute Scores
Potency Severity
3 8
Prevalence Magnitude
1 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
0.1
0.01
0.1

0.008





0.23




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1985
2006








1975




Critical Effect
Plasma & brain ChE inhibition. Q1* 0.000875 (mg/kg-day)-
1 - Likely.
Kidney; liver









mmunological Includ ng Allergic - decrease in humoral
immune response





3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
NCHRL/NCODR290%:70
CAR HRL/NCOD R2 90% : 40
Notes
Reference Dose
Reference Dose; Carpenter et a ., 1961; Basis NOAEL9.6 mg/kg/day, rat, UF=100, kidney & liver
Reference Dose
Reference Dose; Carpenter et a ., 1961; Basis NOAEL/LOAEL, rat, UF=100, kidney & liver
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; ora
Pharmacology. (Academic Press, Inc., 1 E.
Volume(issue)/paqe/year32,587,1975
study in rabbit; TXAPA9 Toxicology and Applied
First St., Duluth, MN 55802) V.1- 1959-
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification



0.000875
Likely to be
carcinogenic in
humans
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mgflsg-d)-1





2003
2007




incidence of hemangiosarcomas in mice





2002 and 2007 Carbaryl Occupational Risk Assessment in August 2008 Amended RED
2003 and 2007 Carbaryl Occupational Risk Assessment in August 2008 Amended RED
Vol. 12, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC

Y
0.4
70
40
0.09
Y/N
Y/N
mg/L
ug/L
ug/L
mg/L


2006




Teratogen




EPA; IARC
UMD
Drinking Water Equivalent Level


Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
Carbaryl
                                                                                          EPA-OGWDW
August 2009
CCL 3 Contaminant Information Sheet Page 500 of 1 124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


12,679



13



0.103



0.18



3



0.18



1



3

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratio (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,142
85

# Sam pies
85

Amount
Released
4,857,542
25
3,475
# PWSs/Sites/
Samples
0.296
0.550


4,671
697
14

#with Detects
14

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


2
0
1
9.76
16.5

% Samples with
detects
17
0.12
Number of
States
48
3
7
% PWSs/Sites/
Samples with
detects


0.9
0
0.02
0.0005


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects




3.5
Non-cancer: 70
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



33.5


Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


0.041
Not Detected
3.5
0.0167
0.04

Median value of
Detects
0.17
0.9
0.138


90% of
Detects


1.2


99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




3.5
90% of
Detects




3.5
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer: 40



Notes
Pesticide Data Program (USDA); 2001
Pesticide Data Program (USDA); 2002
Pesticide Pilot Mentoring Program (USGS/EPA) 2001 (GCMS)
Pesticide Pilot Mentoring Program (USGS/EPA) 9060 (HPLC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Insecticide; veter nary medication (HSDB)
Value
38
242
2.36

4.36E-09
110
18
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation







-------
Carbendazim
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 501 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbendazim
21347
10605217
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.03





0.588



2,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1995





1989



1991
Critical Effect





Liver effects: hepatic cirrhosis, swollen, vacuolated
hepatic cells, & mild chronic hepatitis





Brain and Coverings - other degeneratve changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; TXCYAC Toxicology. (Elsevier Scientific Pub.
reland, Ltd., POB85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year 57,173,1989
Supplemental Data


Dog; PEMNDP Pesticide Manua . (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath
CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,123,1991
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Carbendazim
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 502 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide (HSDB)
Value
>35days
350


2.10E-11

33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DS






Notes
DS = Degrades slow (HSDB)







-------
Carbon disulfide
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 503 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Carbon disulfide
2629
75150
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1







139



1,200
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987









1966




Critical Effect

Fetal toxicity/malformations

Fetal toxicity/malformations







Cardiac - changes in heart weight, Endocrine -
hyperglycemia, Immunological Including Allergic -
decrease in cellular immune response



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude .,, „
10 3 NL!'L!
HRL Ratio(s)
NC HRL/NAWQA 90%: 5,426
Notes
Reference Dose
Reference Dose; Basis NOEL = 1 1 mg/kg-d, rabbit, oral, UF = 1 00 (Hardin et al., 1 981 )
Reference Dose
Reference Dose; Basis NOEL, MF= 1, UF = 100, rabbit (Hardin et al., 1981)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rabbit; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 31 (1 ), 1 3, 1 966
Supplemental Data


INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki,
213 Japan) V.1- 1963- Volume(issue)/page/year 32,145,1994
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

700

Y/N
Y/N

ug/L
ug/L






Developmental (male & female); Teratogen



CACART; UMD
CACART; UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Carbon disulfide
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 504 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,606


# Sam pies

Amount
Released

6,902
26,946,784
# PWSs/Sites/
Samples
1,075

606


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
4

23.3


% Samples with
detects

Number of
States

11
32
% PWSs/Sites/
Samples with
detects
0.37

0.001


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.55

Non-cancer: 5,426
Amount Range
>100-500M
>10-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



34


Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
34

0.02


Median value of
Detects

0.129


90% of
Detects

3.4


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
14.4

90% of
Detects
29.5

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former insecticide/fumigant; rubber additive; industria solvent; chemical intermediate (HSDB)
Value

1
1.94

0.0144
1,180

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS =Biodegrades s ow (BIODEG)







-------
Catechol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 505 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Catechol
5350
120809
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











65




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001




Critical Effect











Blood -changes in serum composition (e.g. TP,
bilirubin, cholesterol) IARC say that it causes
hyperplacia of the fore stomach and pyloric mucosa
which is consistent with the cancer response but does
not identify the study or dose.




Prevalence Magnitude ,,, _
10 6 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JTPAE7 Journal of Toxicologic Pathology. (Nihon
Dokusei Byori Gakkai, editor, 3-25-8 Nfshi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988
Volume(issue)/page/y ear 29,180,2001
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1







1999












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


152

Y/N
Y/N

ug/L
ug/L










IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Catechol
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 506 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released

26,494
35,91 1
# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States

25
30
% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year

2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical antiox dant; chemical intermediate for insecticides and PPCPs (HSDB)
Value

118
0.88

1.20E-09
461,000
37
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
CFC-11
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 507 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
CFC-1 1
2673
75694
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.3
0.3
0.7












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect

Survival & histopathology. Increased mortality,
incidence of pleuritis & pericalditis

Survival & histopathoogy












Prevalence Magnitude , „ ,
8 7 Li L
HRL Ratio(s)
NC HRL/NCOD R1 90%: 247
Notes
Reference Dose
Reference Dose; Basis LOAEL = 488 mg/kg-d, Adjusted Basis LOAEL = 349 mg/kg-d, UF = 1 000,
rat, oral (NCI, 1978)
Reference Dose
Reference Dose; Basis LOAEL, MF = 1, UF = 1000, rat& mouse (NCI, 1978)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

10
2,100

Y/N
Y/N
mg/L
ug/L
ug/L










EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   CFC-11
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 508 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

16,851
23,341


249
265


1.48
1.14


0.01
0.0014


1,444
105


1.3
0.85


8.5
5


72
24.9

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,340


# Sam pies
Amount
Released

54
266,643
# PWSs/Sites/
Samples
12,179
104


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
51
2.4


% Samples with
detects
Number of
States

3
13
% PWSs/Sites/
Sam pies with
detects
0.42
0.007


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.5

Non-cancer: 247
Amount Range
100M-500M
50M-100M
Units
Ibs/yr
Ibs/yr
Year
1990
1994



24


Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
46
0.143


Median value of
Detects
1.1


90% of
Detects
17


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1.8
90% of
Detects
13.4
Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; chemical intermediate; in fire extinguishers; in insulation blowing; in aerosols - major uses now phased out (HSDB); gas
Value

48.6
2.53

0.0971
1,100

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
CFG-12
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 509 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
CFC-12
2674
75718
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.2
0.2
0.2







14




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987




Critical Effect

Reduced body weight

Reduced body weight







Behavioral - alteration of classical conditioning, Blood -
changes in erythrocyte (RBC) count, Bochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - true cholinesterase




Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 77.8
Notes
Reference Dose
Reference Dose; Basis NOAEL = 15 mg/kg-d, rat, UF = 100, oral (Sherman, 1974)
Reference Dose
Reference Dose; Basis NOAEL/LOAEL, MF = 1, UF = 100, rat, whole body (Sherman, 1974)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 52(3), 73,1 987
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


5
1,400

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   CFG-12
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                         EPA-OGWDW
    August 2009
Page 51 Oof 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

16,076
22,145


221
285


1.37
1.29


0.1
0.1


405
230


2
1.22


18
8


200
27.7

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,341

# Sam pies


Amount
Released

10
224,225
n
PWSs/Sites/Sa
mples
12,205

108

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
271

2.49

% Samples with
detects


Number of
States

2
15
/O
PWSs/Sites/Sam
pies with
detects
2.22

0.01

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.5

Non-cancer: 77.8
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1990
1994



38

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
160

0.2

Median value of
Detects


0.6

90% of
Detects


4.3

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
2.4

90% of
Detects
6.5

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; n insulation blowing; in aerosols - major uses now phased out (HSDB); gas
Value
38 days
48.6
2.16

0.343
280
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Chloral Hydrate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 511 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chloral Hydrate
6463
302170
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1









1




Units
mg/kg-d
mg/Kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2000














Critical Effect

CNS depression and Gl irritation









Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification



106

3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
mg/kg-d







1995






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N
mg/L
W/L
W/L










Prevalence Magnitude
10 8 Li
HRL Ratio(s)
NCHRL/DBPICR90%: 58.3
Notes
Reference Dose
Reference Dose; basis LOAEL - 10.7 mg/kg-d, UF = 100, oral human study; Goodman and Oilman,
1985.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 11 3095 Moscow, USSR) V.1- 1936-
Supplemental Data







Tumorigenic Dose - 50





Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chloral Hydrate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 512 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR finished water




# PWSs/Sites
sampled
10,911




#with Detects
7,913




% PWSs/Sites
with detects
72.5




Mean value of
Detects
5.47




Maximum
value of
Detects
92.2




Median value of
Detects
4




90% of
Detects
12




99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, etal., 2006

HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



n
PWSs/Sites/Sa
mples





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States



%
PWSs/Sites/Sam
pies with
detects
75




Units
States
States
States
Minimum value of
Detects


Non-cancer: 58.3
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects
16










Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes



National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
1

90% of
Detects


Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et a/, 2006. Env.Sc/.
Techno!. , 40, pp 71 75-71 85 (and related documentation).

Cancer:







Sedative; hypnotc; in organic synthesis (HSDB)
Value
38
82
0.99

5.71 E-09
793,000
41
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Chlorendicacid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 513 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorendic acid
5103
115286
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.091


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1







1990











Vol. 48
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.385
Y/N
Y/N

W/L
W/L










CACART; IARC; OEHHA
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorendicacid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 514 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>500K - 1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame retardant in textiles and building materials (HSDB)
Value
180 days
49
2.3

3.00E-14

6
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Chlorethoxyfos
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 515 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorethoxyfos
36627
54593838
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0006










0.0495



2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
1996
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Plasma, RBC, and/or Brain ChE inhibition










Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - true cholinesterase



Behavioral - somnolence (general depressed activity),
Behavioral - food intake (animal), Gastrointestinal -
changes in structure or function of salivary glands
Prevalence Magnitude , „
7 5 L'
HRL Ratio(s)
NC HRL/SW Chronic EEC: 52.5
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
TOXID9Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
Volume(issue)/page/year30,124,1996
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0536238
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4.2

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorethoxyfos
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 516 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies
Amount
Released
252,792



OPP Estimated Environmental Concentration

HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects
Number of
States
10





Minimum value of
Detects
Units
States
States
States



Maximum
value of
Detects
Year
1997



Surface water chronic: 0.08 ug/L

Non-cancer: 52.5
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic: 0.002 ug/L

Cancer:








nsecticide (HSDB)
Value
4.3-59 days
890


4.20E-06

5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DST






Notes
DST = Degrades sometimes/recalcitrant (HSDB)







-------
Ch loroacetaldehyde
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 517 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Chloroacetaldehyde
4598
107200
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification



36.1


LM
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
mg/kg-d

















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N
mg/L
W/L
W/L










Prevalence Magnitude
10 5
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







Tumorigenic Dose - 50


DSSTOX; LM = Low to medium probability of being carcinogenic

DSSTOX

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ch loroacetaldehyde
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 518 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total

Krasner, et al.

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States


%
PWSs/Sites/Sam
pies with
detects
50





Units
States
States
States
Minimum value of
Detects


Non-cancer:
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
2.4













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0,2

90% of
Detects


Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, eta/, 2006. Env. Sci.
Technol. , 40, pp 7175-7185 (and related documentation).

Cancer:







Disinfection By-Product
Value
15
39
0.39

2.39E-05
111,000
45
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades Slow







-------
Chloroacetyl chloride
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 519 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroacetyl chloride
2856
79049
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Supplemental Lowest Oral LD50
Value













208


207
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date













1991



Critical Effect
















Weakness and collapse; effects on ungs liver and
gastrointestinal tract on necropsy
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Rat (American Conference of Governmental Industril Hygeinists, Inc. Documentation of the Threshold
Limit Values and Biological Exposure Indices. 6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH, 1991., p.


OPPTS; Monsanto study 1992 OST0536760
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


14.5

Y/N
Y/N

W/L
W/L










UMD

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
    Chloroacetyl chloride
    CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 520 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,fl, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


^Samples

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; tear gas (HSDB)
Value

4
-0.22

0.00023

43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Chlorobenzilate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 521 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorobenzilate
7384
510156
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02

0.02

0.02





35.3




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1989



1980





1972




Critical Effect

Decreased food intake, weight gain, stool quantity, and
hyperirritablility









mmunological Includ ng Allergic - decrease in cellular
immune response





3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Basis NOEL = 5 mg/kg-d, rabbit, oral (Ciba-Geigy, 1984a)
Reference Dose
Reference Dose; Basis NOEL/LEL, MF = 1, UF = 300, rabbit (Ciba-Geigy Corp., 1984)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 17-week oral study in rat; FATOAO Farmakologiya i
Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya
Kniga, 1 1 3095 Moscow, USSR) V.2- 1939- Vo ume(issue)/page/year 35(3), 352,1972
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.27
0.11


3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1987











Vol. 30, Suppl. 7, 1987
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


140
0.318
Y/N
Y/N

W/L
W/L










CACART; IARC; OEHHA; RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorobenzilate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 522 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released

0
5
n
PWSs/Sites/Sa
mples
117


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0


% Samples with
detects

Number of
States

0
1
%
PWSs/Sites/Sam
pies with
detects
0


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected


Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide (HSDB)
Value

1,263
4.74

7.24E-08
13

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Chloroethane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 523 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroethane
2616
75003
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
4 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol. 52, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

W/L
W/L










CACART; Equivocal evidence of carcinogenicity in male and female rats; clear evidence in female mice;
nadequate study in male mice (NTP).

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Chloroethane
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
    August 2009
Page 524 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

20,236
24,433


78
84


0.385
0.344


0.10
0


112
288


1.00
1.30


9.7
6.85


64
84.5

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,271

# Sam pies

Amount
Released

586
732,853
n
PWSs/Sites/Sa
mples
11,930

39

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
44

0.913

% Samples with
detects

Number of
States

5
15
%
PWSs/Sites/Sam
pies with
detects
0.37

0.0175

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.5

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



40

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
46

0.06

Median value of
Detects

1

90% of
Detects

40

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1.3

90% of
Detects
2.3

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermed ate; solvent; refrigerant; medication (HSDB); gas
Value

23.7
1.43

0.0111
6.71

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Chloromethyl methyl ether
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 525 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloromethyl methyl ether
4605
107302
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


2A

A
1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1






1988











Oral

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.0146
Y/N
Y/N

W/L
W/L










EPA; UMD; IARC;OEHHA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chloromethyl methyl ether
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 526 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
1,085
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

2.38
0.32

0.000303
69,400

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Chlorophenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 527 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorophenol
28429
25167800
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.005





0.003







570
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







2000








Critical Effect

Reproductive effects - Ortho isomer





mmune system- Rat







Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
66 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Basis NOAEL = 0.3 mg/kg-d, rat, UF = 100, oral (Exon and Koller, 1985)
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rat, oral; BSLIB Biochemistry Section, Laboratory Investigations Branch, DRDS, ALOSH, NIOSH
Volume(issue)/page/year -,1,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorophenol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 528 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

76
43,439
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
6
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; disinfectant; veterinary med cation (HSDB - uses for 2-chloropheno , 3-chlorophenol and 4-chlorophenol)
Value
15 days

2.16

4.15E-07
28,500
29
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Chloropicrin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 529 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloropicrin
2704
76062
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











32




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1965










Critical Effect











Gastrointestinal - other changes, Blood - changes in
serum composition (e.g. TP, bilirubin, cholesterol),
Nutritional and Gross Metabolic - weight loss or
decreased weight gain




Prevalence Magnitude
10 6 NLi
HRL Ratio(s)
NC HRL/DBP ICR 90% : 93.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; (DCTODJ Drug and Chemical Toxicology. (Marcel Dekker,
270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year 17,125,1994)
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



74.7

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chloropicrin
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 530 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR



# PWSs/Sites
sampled
10,905



#with Detects
2,837



% PWSs/Sites
with detects
26.02



Mean value of
Detects
1



Maximum
value of
Detects
13.6



Median value of
Detects
0.8



90% of
Detects
1.61



99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Supplemental Water Data
Krasner, et al.
HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
13,882,188
0
14,865
n
PWSs/Sites/Sa
mples
4
# PWSs/Sites
sampled
12


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
#with Detects
6


% Samples with
detects

Number of
States
29
0
8
%
PWSs/Sites/Sam
pies with
detects
25
% PWSs/Sites
with detects
50


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.5
Minimum value of
Detects

Non-cancer: 93.4
Amount Range

1M-10M
Units
Ibs/yr
Ibs/yr
Year

1986





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
1.5
Maximum
value of
Detects
2


Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L
Notes




Units for Mag
data
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L



National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1
Median value of
Detects
0.2
99% of
Detects
1.4
75% of
Detects
0.4
Units for Mag
data
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Techno!. , 40, pp 71 75-71 85 (and related documentation).




Rodenticide; fumgant; tear gas (HSDB)
Value

81
2.09

0.00205
1,621
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Chloroprene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 531 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chloroprene
5636
126998
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.02







0.05




Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1980




Critical Effect



Alopecia







Liver - changes in liver weight, Endocrine - changes in
spleen weight, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - dehydrogenases




Prevalence Magnitude ,,, „
3 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis NOAEL, MF = 1 , hair, rat, UF = 1 00 (USEPA, 1 989).
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 45(2), 17,1 980
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

140

Y/N
Y/N

W/L
W/L










CACART; IARC
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chloroprene
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 532 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

74
925,010
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
3
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in adhesives (HSDB)
Value
15 days
67.7
2.53

0.056
875
74
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Chlorothalonil
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 533 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Chlorothalonil
12375
1897456
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.015
0.015
0.015

0.03




1.5
75




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987



1994





1990




Critical Effect
Increased kidney weights & hyperplasia of the
proximal convoluted tubules in the kidneys, ulcers &
forestomach hyperplasia. Q1 * 0.00766 (mg/kg-day)-1 .
Group B2. See CAR
Renal tubular epithel al vacuolation

Tubular epithelial vacuolation







Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Kidney, Ureter,
Bladder - changes in bladder weight




Prevalence Magnitude ,,, „
4 4
HRL Ratio(s)
NCHRL/NAWQA90%: 342
CAR HRL/NAWQA 90% : 3.66
Notes
Reference Dose
Reference Dose; Basis NOEL =1.5 mg/kg/day, UF = 100, kidney, dog, oral (Diamod Shamrock Chemical,
1970a)
Reference Dose
Reference Dose; Basis NOEL/LEL, MF = 1, kidney, dog, UF = 100 (Diamod Shamrock Chemical, 1970)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; OPP RfD
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
53,155,1990
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
EPA Lifetime Cancer Risk, 1CT5
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.15
0.5
0.011
0.0031
0.00766
B2
2B
mg/L
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1








1999








Corresponds with OPP slope factor.


OPP

Vol. 73, 1999; note: OEHHA lists lARCs cancer class as 3.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.5
140
1.5
Y/N
Y/N
mg/L
W/L
W/L










CACART; IARC; EPA; OEHHA; RAIS
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Chlorothalonil
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 534 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,547

# Sam pies

Amount
Released
11,916,713
6
303,181
n
PWSs/Sites/Sa
mples
4,099
29


15

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0

0
0
0.33

% Samples with
detects

Number of
States
48
2
7
%
PWSs/Sites/Sam
pies with
detects
0



0.007

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
Non-cancer: 342
Amount Range


Fungicide; bacter
Value

2,392
3.05

2.00E-06
0.6

Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.71

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
0.05

Median value of
Detects

0.41

90% of
Detects

0.71

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
90% of
Detects
Not Detected
Not Detected
Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer: 3.66



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide Data Program (USDA)
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient (HPLC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) Finished (HPLC/MS)




ocide (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cinnamaldehyde
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 535 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cinnamaldehyde
4388
104552
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










550
0.208



1,160
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1992




Critical Effect










Slight decrease in body weight
Liver - changes in liver weight, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue levels -
hepatic microsomal mixed oxidase (dealkylation,
hydroxylation, etc.), Related to Chronic Data - death



Behavioral - coma
Prevalence Magnitude ,,,
5 7 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal; Bickers, et al. Food and Chemical Toxicology 43 (2005) 799-836
Lowest Observed Adverse Effect Level; 24-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 49,306,1992
Supplemental Data


FCTXAV Food and Cosmetics Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information,
see FCTOD7. Volume(issue)/page/year 2,327,1964
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3,850

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cinnamaldehyde
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 536 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; attractant in insect control (HSDB)
Value
1 5 days

0.19


1,420
33
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Citric acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 537 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Citric acid
2776
77929
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








100


620



3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - other transferases, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol)



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
85 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD); MRDDs were only used for screening,
not for attribute scoring.
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O MezhdunarodnayaKniga, 113095 Moscow, USSR) V,1- 1936-
Volume(issueXpage/y ear -,65,1993
Supplemental Data


OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 1 80, Sendai 980-91 , Japan)
V.1- 1967- Voume(issue)/page/year 43,561, 1992
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,447

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Citric acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 538 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; medication; pesticde (HSDB)
Value

3.1
-1.64

4.30E-14
383,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Clomazone
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 539 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Clomazone
66450
81777891
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.84














1,369
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Hydronephrotic kidneys in male offspring, decreased
body weight, decreased pup weight














Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NC HRL/ SW Chronic EEC: 256
Notes
Reference Dose; TRED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,178,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



5,880

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Clomazone
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 540 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies

Amount
Released
2,531,160



OPP Estimated Environmental Concentration
HRL Ratios (HRL/ SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
36





Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997
2004
2004

Surface water chronic: 23 ug/L
Non-cancer: 256
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic: 2.4 ug/L
Cancer:







Herbicide (HSDB)
Value

60-573
2.5

4.13E-08
1,100
18
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Co bait compounds
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 541 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cobalt compounds
38

Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












72
150


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date













1982


Critical Effect












decreased fertility and preimplantation loss



Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Journal; Pedogo and Vernon 1993; Chemical tested forthe supplemental
LOAEL was CoCI2.
Speijers, G., et al; Food Chem Toxicol., 20(3): 311-314. Rat study


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



168

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Co bait compounds
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 542 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

86,313
6,910,811
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

30
45
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additives as drying agents; glass additives; catalysis (HSDB)
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
Coumarin
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 543 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Coumarin
3492
91645
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











100
16
1.67



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1956/1982
2006




Critical Effect











Liver -jaundice, other or unclassified, Blood - hemorrhage,
Related to Chronic Data - death;
Liver - hepatitis (hepatocellular necrosis), diffuse, Liver -
iver function tests impaired, Blood - changes in platelet
count
Hepatotoxicity; liver effects.




Prevalence Magnitude ,,, „
5 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake

No Observed Effect Level (2006)
Supplemental Data (2006)
Lowest Observed Adverse Effect Level from two studies: JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 118,348,1956.
NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0555582.
Supplemental Data; Journal; Food and Chemical Toxicology 44 (2006) 462-475
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

37.3

Y/N
Y/N

W/L
W/L






Teratogen



IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Coumarin
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 544 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; former food additive (suspended 1954); in PPCPs (HSDB)
Value

140
1.39

9.90E-08
1,900
38
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cresol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 545 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cresol
11192
108394
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












256


760
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












Increased absolute and relative liver weight



Prevalence Magnitude
10 9
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; NTP; NTP Tox-09



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



597

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cresol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 546 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

61,486
1,475,929
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

23
35
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; chemical intermediate; degreaser; veterinary medicaton (HSDB)
Value

22
1.95

1.20E-06
25,900
32
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cryolite
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 547 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cryolite
24566
15096523
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











23.1
95


5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral - food intake (animal), Liver - other changes,
Kidney, Ureter, Bladder - other changes
Increases in emesis, nucleated cells in males, renal
lesions, and a decrease in urine specific gravity.


Gastrointestinal - changes in structure or function of
salivary glands, Skin and Appendages - hair
Prevalence Magnitude , „
87 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; BGTOX BG Chemie Toxicological Evaluations, Five Potential
Health Hazards of Existing Chemicals. (Springer- Verlag New York, POB 2485, Secaucus, NJ 07096).
Supplemental Data; EPA OPP (RED)


BAYER (Bayer. AG, Institute fur Toxikologie, Wuppertal, Germany) Volume(issue)/page/year
#15722,1987
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



222

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cryolite
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 548 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
2,560,365


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
13


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide; industrial electrolyte; medication (HSDB)
Value
Assumed
persistent




250-320

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Cupferron
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 549 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cupferron
5877
135206
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude ,,, ,,, „
1 1 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.22



mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.159
Y/N
Y/N

W/L
W/L










OEHHA; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cupferron
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 550 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Laboratory reagent (HSDB)
Value
15 days




Freely soluble
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Cure-Rite 18
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 551 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cure-Rite 18
23329
13752517
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











35.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Kidney,
Ureter, Bladder -other changes, Nutritional and Gross
Metabolic - weight loss or decreased weight gain




Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS0536514
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



82.7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cure-Rite 18
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 552 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rubber accelerator (West Coast Polychem.com - manufacturer)
Value
38 days





47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Cyanazine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 553 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanazine
27282
21725462
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.002
0.002







0.985




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2000




Critical Effect



Reduced body weight and body weight gain, increased
platelet count, decreased protein, albumin and calcium







Behavioral - food intake (animal), Reproductive - Maternal
Effects- breasts, lactation (prior to or during pregnancy),
Tumorigenic - carcinogenic by RTECS criteria




Prevalence Magnitude , „ ,
94 L' L
HRL Ratio(s)
NC HRL/NAWQA 90% : 16.5
CAR HRL/NAWQA 90% : 0.049
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1993; Basis NOEL, dog, UF = 300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 371 -day oral study in rat; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volume(issue)/page/year 60,567,2000
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.84




mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ
CADWIMAC
Y
Y
0.07
14
0.042
0.6
0.01
Y/N
Y/N
mg/L
W/L
W/L
W/L
mg/L








Developmental; Teratogen





RAIS
CACART; UMD
Drinking Water Equivalent Level


World Health Organization Drink ng Water Guide
Canadian Drink ng Water Interim Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cyanazine
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 554 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,164

# Sam pies

Amount
Released
20,233,056
0
370
n
PWSs/Sites/Sa
mples
317


33
590

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

145
3
0
8.24

% Samples with
detects

Number of
States
48
0
1
%
PWSs/Sites/Sam
pies with
detects

44.9
42.1
0
0.002

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects



Not Detected
Non-cancer: 16.5
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



160

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

0.332
0.355
Not Detected
0.039

Median value of
Detects

0.849

90% of
Detects

6.7

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



Not Detected
95% of
Detects

0.007
0.128
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer: 0.049



Notes
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient
Pesticide Pilot Monitoring Program (USGS/EPA) Finished
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Cancelled herbicide (HSDB)
Value

124
2.22

2.96E-12
170

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Cyanogen chloride
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 555 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Cyanogen chloride
7358
506774
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
WHO TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.05





0.054








Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1995














Critical Effect

Weight loss, thyroid effects and myelin degenration














Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification



D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


2
350

Y/N
Y/N
mg/L
W/L
W/L










Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NCHRL/DBPICR90%: 43.8
Notes
Reference Dose
Reference Dose; basis NOAEL = 25.3 mg/kg-d, UF/MF = 500; chronic oral rat study; Howard and
Han zal, 1955.
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cyanogen chloride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 556 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR finished water




# PWSs/Sites
sampled
1,745




#with Detects
1,358




% PWSs/Sites
with detects
78




Mean value of
Detects
3.69




Maximum
value of
Detects
21




Median value of
Detects
2.7




90% of
Detects
8




99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released



# Sam pies




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States



% Samples w/
Detects




Units
States
States
States
Minimum value of
Detects

Non-cancer: 43.8
Amount Range


Military gas; warn
Value
15

-0.38

2.50E-02
60,000
44
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year



Maximum
value of
Detects










Units for Mag
data

ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes



National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

95% of
Detects

Units for Mag
data
Notes

Cancer:







ng agent in fumgants; in chemica sysnthesis (HSDB)
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades Slowly







-------
Cyanuric acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 557 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanuric acid
4719
108805
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









150

30



3,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1962




Critical Effect









Functional and histopatological effects in the kidney;
increases in absolute and relative kidney weights and
relative adrenal weights.

Kidney, Ureter, Bladder - other changes, Nutritional
and Gross Metabolic - weight loss or decreased weight
gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
8 3 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat; QISAAA Qigiena i Sanitariya.
For English translation, see HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/page/year 27(1 2),1 3,1 962; The LOAEL was used for Potency scoring because
it was lower than the NOEL from other studies.
Supplemental Data


ZKMAAXZhurnal Eksperimental'noi i Klinicheskoi Meditsiny. Journal of Experimental and Clinical
Medicine. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1962-
Volume(issue)/page/year25,345,1985
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



70

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyanuric acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 558 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100-500M
>100-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; laboratory reagent (HSDB)
Value

66-124


1.38E-18
2,000
23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cyanuric chloride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 559 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyanuric chloride
4716
108770
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











100



350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1392




Critical Effect











Liver - changes in liver weight, Blood - pigmented or
nucleated red blood cells, Related to Chronic Data -
death



Behavioral - somnolence (general depressed activity),
Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain
Prevalence Magnitude ,,, „
8 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 lexicologist. (Soc. of Toxicology, Inc., 475 Wolf
Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue);page;year 12,119,1992; 28 day study
in rat
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information,
see MTPEEI Vo ume(issue)/page/year 12(81,35,1968
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



233

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cyanuric chloride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 560 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10M-50M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
60
124


4.90E-07

34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
Cyclanilide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 561 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclanilide
69562
113136779
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











21.2



208
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1997




Critical Effect











Liver- liverfunction tests impaired, Liver-other
changes, Liver - changes in liver weight



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „, „ , „
7 5 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; FEREAC Federal Register. (U.S. Government Printing
Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year
62,28350,1997
Supplemental Data


FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC
20402) V.1- 1936- Volume(issue)/page/year 62,28350,1997
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



49.5

Y/N
Y/N

W/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyclanilide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 562 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
177,086


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
9


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide; plant growth regulator (HSDB)
Value
95 days
194-565
3.25

7.31 E-10


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reclaitrant (HSDB)







-------
Cyclohexane
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 563 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexane
4884
110827
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















813
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg*g
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NPIRI Raw Material Data Handbook, Vol.1 Organic Solvents, 1974. (National Assoc. of Printing Ink
Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA
1801 5) Volume(issueXpage/year 1 ,17,1 974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



56.9

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyclohexane
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 564 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released

10,761
4,761 ,999
# PWSs/Sites
sampled




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




Number of
States

26
49
% PWSs/Sites
with detects




Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year
1997
2004
2004
Maximum
value of
Detects










Units for Mag
data

ug/L




ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Value
15 days
160
3.44

0.15

54
Units
length of time
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Cyclohexanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 565 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexanol
4730
108930
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral -somnolence (general depressed activity),
Lungs, Thorax, or Respiration - other changes,
Nutritional and Gross Metabolic -weight loss or
decreased weight gain
Prevalence Magnitude , „ ,
8 10 Li L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS053861 7
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



98

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Cyclohexanol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 566 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

9,053
4,538,466
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

3
13
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>500M-1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate (HSDB)
Value

13-111
1.23

0.00012
42,000
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Cyclohexanone
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 567 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexanone
4731
108941
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

5

5







0.05




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986









1994




Critical Effect

Body weight depression

Body weight depression







Behavioral - alteration of classical conditioning




Prevalence Magnitude
10 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Lijinsky and Kovatch, 1986; Basis NOAEL =462 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Lijinsky and Kovatch, 1986; Bass NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,455,1994
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35,000

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyclohexanone
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 568 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; degreasing agent; solvent; chem cal intermediate (HSDB)
Value

15.2
0.81

9.00E-06
25,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cyclohexylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 569 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyclohexylamine
4729
108918
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.2

0.2







97.8



11
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1958




Critical Effect

Testicular damage. Testicular atrophy, decreased
fertility & live young/litter

Testicle







Liver - other changes, Kidney, Ureter, Bladder - other
changes



Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Gastrointestinal - other
changes
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Gaunt el al., 1976; Basis NOAEL = 18 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Gaunt et al., 1976; Basis NOAEL/LOAEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in rat;VOONAW Voprosy Onkologii. Problems
of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow,
USSR) V. 1-10, 1928-37; V.1- 1955- Volume(issue)/paqe/year 4,659,1958
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year OTS0534836
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,400

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyclohexylamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 570 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; boiler water additive; rubber accelerant (HSDB)
Value

40.4
1.49

4.16E-06
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Cyfluthrin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 571 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyfluthrin
48890
68359375
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.025

0.025

0.02









300
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986














Critical Effect

Decreased body weights in males, inflam matory foci in
kidneys of females

Decreased body weights in males, inflammatory foci in
kidneys of females











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 5 L'
HRL Ratio(s)
NCHRL/SW Chronic EEC: 1,346
Notes
Reference Dose
Reference Dose; Mobay Chemical, 1983a; Basis NOEL = 2.5 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose; Mobay Chemical, 1983a; Basis NOEL/LEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; from JECFA evaluation
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


85KYAH "Merck Index; an Encyc opedia of Chem cals, Drugs, and Biologicals", 1 1th ed., Rahway, NJ
07065, Merck&Co., Inc. 1989 Volume(issue)/page/year 11,432,1989
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



175

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyfluthrin
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 572 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP



# Sam pies


Amount
Released
177,782
0
0
n
PWSs/Sites/Sa
mples
134
265

OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects


Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects


0



% Samples with
detects


Number of
States
29
0
0
%
PWSs/Sites/Sam
pies with
detects


0



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects


Not Detected



Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Not Detected
Surface water chronic: 0.13 ug/L
Non-cancer: 1,346
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
99% of
Detects


Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Finished and Ambient
Ground water chronic: 0.00336 ug/L
Cancer:







nsecticide; medication (HSDB)
Value

179,000
5.95

1.50E-10
0.003
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Cypermethrin
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 573 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cypermethrin
35676
52315078
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.06
0.01

0.01

0.05





25



24.6
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1989



1996





1985




Critical Effect
Clinical signs of neurotoxicity & mortality; decreased
body weight £ body weight gain
G.I tract disturbances

G.I tract







mmunological Includ ng Allergic - decrease in cellular
immune response, Immunological Including Allergic -
decrease in humoral mmune response



Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Gastrointestinal - changes in structure or function of
salivary glands
Prevalence Magnitude , „ ,
10 5 L"L
HRL Ratio(s)
NC HRL/SW Chronic EEC: 32,308
Notes
Reference Dose; ICI Americas, Inc., 1982a
Reference Dose; ICI Americas, Inc., 1982a; Basis NOEL = 1 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; ICI Americas, Inc., 1982a; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake; from JECFA evaluation
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 3-week oral study in rat; ATSUDG Archives of Toxicology,
Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)
No.1- 1978- Volume(issue)/page/year 8,305,1985
Supplemental Data


JEBIDP Journal of Environmental Biology. (Academy of Environmental Biology, India, 657/5, Civil Lines
(South), Muzaffarnagar, 251001, India) V.1- 1980- Volume(issue)/page/year 11,331,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

420

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cypermethrin
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 574 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP

# Sam pies

Amount
Released
187,991


n
PWSs/Sites/Sa
mples
134
380

OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects


0

% Samples with
detects

Number of
States
29


/O
PWSs/Sites/Sam
pies with
detects


0

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


Not Detected
Surface water chronic: 0.013 ug/L
Non-cancer: 32,308
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
99% of
Detects


Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program 2001
Pesticide Data Program 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Finished and Ambient
Ground water chronic: 0.0036 ug/L
Cancer:







nsecticide; veter nary medication (HSDB)
Value

108,000
6.06

4.21 E-07
0.004
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Cyromazine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 575 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Cyromazine
42395
66215278
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0075

0.0075

0.02









3,387
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

Effects on hematocrit & hemoglobin levels

Blood











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, ,,, „
7 3 NL NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Ciba-Qeigy, 1980; Basis NOEL = 0.75 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; Ciba-Geigy, 1980; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,217,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



52.5

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Cyromazine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 576 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
14,297


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
6


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide; medication (HSDB)
Value
60 days
2,104
0.96

5.65E-14
13,000
44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Dacthal
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 577 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dacthal
12322
1861321
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01
0.01
0.01
0.01












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1994














Critical Effect
Effects on the lungs, liver, kidney (chronic
nephropathy), thyroid. Decreased T4 & T3.
Centrilobular hepatocyte swelling (hepatocytic
hypertrophy)
Lungs; liver; kidney; thyroid; eyes
Lungs; liver; kidney; thyroid;













Prevalence Magnitude ,,, „
9 2 NL'
HRL Ratio(s)
NC HRL/NAWQA 90%: 2,800
Notes
Reference Dose; ISK Biotech Corp., 1993
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL = 1 mg/kg-d, rat, UF = 100
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL/LOAEL, rat, UF = 100
Reference Dose; ISK Biotech Corp., 1993; Basis NOAEL/LOAEL, rat, UF = 101
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1






1988













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.4
70

Y/N
Y/N
mg/L
W/L
W/L


1988









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dacthal
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 578 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118

# Sam pies


Amount
Released
596,723


n
PWSs/Sites/Sa
mples
288
582


286
445

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


16
8
1
6.25

% Samples with
detects


Number of
States
38


%
PWSs/Sites/Sam
pies with
detects


5
3.5
0.35
0.000004

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects




0.21
Non-cancer: 2,800
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



100

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


0.014
0.004
0.21
0.003

Median value of
Detects


0.025

90% of
Detects


1

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




0.21
95% of
Detects


0.002

0.21
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient 2001 (GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) Finished 2001 (GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Herbicide (HSDB)
Value
60 days
283
4.28

2.18E-06
0.5
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Dacthal mono di-acid degradate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 579 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dacthal mono/di-acid degradate
79261

Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
Scores based on parent
HEALTH EFFECTS DATA1 See Dacthal parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.01















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Effects on the lungs, liver, kidney (chronic
nephropathy), thyroid. Decreased T4 & T3.
Centrilobular hepatocyte swelling (hepatocytic
hypertrophy)















Prevalence Magnitude , „
97 L
HRL Ratio(s)
NCHRL/UCMR90%: 11.1 (HRL for parent Dacthal)
Notes
Reference Dose (for parent, dacthal); ISK Biotech Corp., 1993
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



70

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on data for parent Dacthal

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Dacthal mono di-acid degradate
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 580 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,612



171



4.73



1



190



2



6.3



18



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118
# Sam pies


Amount
Released



n
PWSs/Sites/Sa
mples
2,217

445
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
39

6.25
% Samples with
detects


Number of
States



%
PWSs/Sites/Sam
pies with
detects
1.76

0.000004
Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
1

Non-cancer: 11.1
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



100
Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
13

0.003
Median value of
Detects


0.025
90% of
Detects


1
99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes

Analytical method reports mono- and di- as total.




(data for parent, dacthal)
National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1.9

90% of
Detects
5.3

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

HRL for parent Dacthal



Degradates of the herbicide dimethyl tetrachloroterephthalate (HSDB)
Value







Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Decabromodiphenyl ether
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 581 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Decabromodiphenyl ether
10800
1163195
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL-Int
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.007

0.01
10





1
800




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

2008


2004






1975, 1994




Critical Effect

Neurobehavioral effects









Liver - other changes, Kidney, Ureter, Bladder - other
changes, Endocrine - changes in thyrod weight (goiter)




Prevalence Magnitude , „ ,
10 8 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis NOEL = 2.2 mg/kg, UF = 300, single-dose gavage in mice. Viberg, et al,
2003.
Reference Dose
Reference Dose; Kociba et al., 1975; Basis NOAEL, rat, UF=100
Minimal Risk Level-lnt
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994. Volume(issue)/page/year -
,316,1994.
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
5


0.0007
Suggestive
evidence
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1


2008


2008
2008







IRIS


IRIS
IRIS

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70
50
Y/N
Y/N

W/L
W/L










EPA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Decabromodiphenyl ether
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 582 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

2,827
953,472
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

9
26
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame retardant; polymer intermediate (HSDB)
Value

409,000
12.1

4.45E-08
0.025
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Decamethylcyclopentasiloxane
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 583 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Decamethylcyclopentasiloxane
7678
541026
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















24,134
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
8 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information, Volume issue)/page/year OTS0572801
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,689

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Decamethylcyclopentasiloxane
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 584 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n PPCPs; chemical intermediate; in petroleum processing (HSDB)
Value
38 days
16,000
5.2

0.306
0.017
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Desethylatrazine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 585 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Desethylatrazine
17458
6190654
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Attenuation of preovultory luteinizing hormone (LH)
surge, as a biomarker indicative of hypothalmic
function disruption















Prevalence Magnitude
10 3
HRL Ratio(s)
NC HRL/NAWQA 90% : 881 (HRL for parent Atrazine)
Notes
Reference Dose; evaluation is based on the RfD for parent (Atrazine).
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



126

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on data for parent Atrazine

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Desethylatrazine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 586 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,151

# Sam pies
Amount
Released



n
PWSs/Sites/Sa
mples
317
154


2,963

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
154
75
203
167
41.4

% Samples with
detects
Number of
States



/o
PWSs/Sites/Sam
pies with
detects
48.6
48.7
89
74.6
Not Detected

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0413
0.0413


Non-cancer: 881
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



10

Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.19
0.22
0.352
0.267
0.017

Median value of
Detects
0.143

90% of
Detects
0.738

99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




95th % lie
value of
Detects


0.265
0.201
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:



Notes
2002
2001


HRL for parent Atrazine



Degradation product of atrazine (HSDB)
Value

24-30,000
1.51

1.50E-09
3,200

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
Desisopropylatrazine
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 587 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Desisopropylatrazine
10412
1007289
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Attenuation of preovultory luteinizing hormone (LH)
surge, as a biomarker indicative of hypothalmic
function disruption















Prevalence Magnitude , „
10 4 L'
HRL Ratio(s)
NC HRL/NAWQA 90% : 200 (HRL for parent Atrazine)
Notes
Reference Dose; evaluation is based on the RfD for parent (Atrazine)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



126

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on data for parent Atrazine

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Desisopropylatrazine
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                              EPA-OGWDW
    August 2009
Page 588 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
418

# Sam pies
Amount
Released



n
PWSs/Sites/Sa
mples
317
154


94

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
127
64
250
146
22.5

% Samples with
detects
Number of
States



/o
PWSs/Sites/Sam
pies with
detects
40.1
41.6
80.1
64.9
0.003

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.0163
0.0163


Non-cancer: 200
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



3.69

Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.0832
0.073
0.386
0.178
0.1

Median value of
Detects
0.63

90% of
Detects
2.04

99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




95% value of
Detects


0.195
0.081
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Cancer:



Notes
2002
2001


HRL for parent Atrazine



Degradation product of atrazine
Value
60 days

1.15

1.16E-09
670
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
D-Glucose
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 589 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
D-Glucose
2156
50997
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












714
100


25,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Critical Effect












Increased heart rate; early dumping syndrome



Behavioral - coma, Lungs, Thorax, or Respiration -
cyanosis, Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude ,,, ,,, „
95
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake

No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Journal -Andrew Ukleja. Feb 2006. "Dumping Syndrome." Practical
Gastroenterology. Series 35: Nutrition Issues in Gastroenterology. pp 32-46. (Series Editor: Carol
Rees Parrish, RD, MS)
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)


85AIAL "Toxicity of Pure Foods," Boyd, E.M., Cleveland, OH, CRC Press, 1973 Volume(issue)/page/year -
,39,1973
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,666

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   D-Glucose
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 590 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; in medical nutrient solutions; chemica ntermediate (HSDB)
Value
8.7 days

-3.24


1,200,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (PBT)







-------
Diallyl glycol carbonate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 591 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diallyl glycol carbonate
6128
142223
Attribute Scores
Potency Severity
4 6
Prevalence Magnitude
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











42.6



279
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999




Critical Effect











Brain and Coverings - recordings from specific areas
of CNS, Liver - liver function tests impaired, Kidney,
Ureter, Bladder - renal function tests depressed



Brain and Coverings - recordings from specific areas of
CNS, Behavioral - somnolence (general depressed
activity), Lungs, Thorax, or Respiration - other changes

3-model Categorical Prediction
NL7-L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii
per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year(2),35,1999
Supplemental Data


TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown
Volume(issue)/page/year (2), 35, 1999
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



99.4

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Diallyl glycol carbonate
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 592 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
38 days





40
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Diallyldimethylammonium chlorid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 593 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diallyldimethylammonium chloride
18770
7398698
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1,000



7,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1984




Critical Effect











Liver -other changes, Kidney, Ureter, Bladder -
changes in tubules (including acute renal failure, acute
tubular necrosis), Nutritional and Gross Metabolic -
weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect level, GTPZAB Qigiena Truda i Professional'nye Zabolevaniya.
Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 1 13095 Moscow, USSR)
V.1 -36, 1957-1992. For publisher information, see MTPEEI Volume(issueXpage/year 28(7),53,1 984;
6 week mammal study
Supplemental Data


rodent-mouse; GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For
publisher information, see MTPEEI Volume(issue)/page/year 28(7), 53, 1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,333

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diallyldimethylammonium chlorid
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 594 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Polymer intermec
Value
1 5 days

-2.49


1,000,000
39
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Diazinon
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 595 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diazinon
6596
333415
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002

0.00009
0.0009
0.0002
0.002





0.143




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1986




Critical Effect
Plasma CUE inhibition


Decreased cholinesterase activity







Liver - fatty liver degeneration, Nutritional and Gross
Metabolic - weight loss or decreased we ght gain




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 1 3.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1984; Basis NOAEL, UF = 100
Minimal Risk Leve ; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year 37,501,1986
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC

Y
0.003
1.4

0.02
Y/N
Y/N
mg/L
M/L
M/L
mg/L







Teratogen





UMD
Drinking Water Equivalent Level


Canadian Drinking Water Maximum Acceptable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
      Diazinon
      CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 596 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300



0



0



Not Detected



Not Detected



Not Detected



Not Detected



Not Detected



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS
HRL Ratios (HRL/NAWQA 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
KOC, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,115
85
# Samples

Amount
Released
918,087
10,287
23,769
n
PWSs/Sites/Sa
mples
283
658

6,743
815
22
#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
1
114
6
11.45
25.9
% Sam pies with
detects
4.89
0.49
Number of
States
37
2
7
%
PWSs/Sites/Sam
pies with
detects
0.4
0.2
35.3
0.09
0.0009

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.01
0.01

0.01
Non-cancer: 13.2
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



19

Maximum value
of Detects

Year
1997
2004
2004
Maximum value
of Detects
0.01
0.01
0.101
507
0.014
0.07
Median value of
Detects
0.125
0.18
0.106

90% of Detects

0.63

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



0.12
90% of Detects



203
95% of Detects


0.002

Cancer:



Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA)
Ambient
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Che
micalcontaminants.aspx




Pesticide; veterinary medication (HSDB)
Value
38 days
1,337
3.81

1.13E-07
40

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Diazinon oxygen analog
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 597 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diazinon oxygen analog
79205

Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
Scores based on parent
HEALTH EFFECTS DATA1 See Diazinon Parent
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0002















Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Plasma ChE inhibition















Prevalence Magnitude ,,,
1 1 NL
Scores based on parent HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose (for parent)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.4

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on data for Parent Diazinon

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Diazinon oxygen analog
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 598 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data- FOR
DIAZINON PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



n
PWSs/Sites/Sa
mples
283
664



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
3



% Samples with
detects

Number of
States



%
PWSs/Sites/Sam
pies with
detects
0.4
0.5



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.04
0.015
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
0.04
0.037



Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes

(Data for parent)




National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


99% of
Detects


Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002




Analog of the pestcide diazinon
Value







Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
    Dibromoacetonitrile (DBAN)
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 599 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dibromoacetonitrile (DBAN)
14629
3252435
Attribute Scores
Potency
5
Severity

Prevalence
10
Magnitude
7
                                                                                                                                                                         3-model Categorical Prediction
                                                                                                          Incomplete data for scoring
HEALTH EFFECTS DATA1
                                                                                                                                                                          NCHRL/DBPICR90%: 14.7
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










6.5





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
IARC Carcinogen Classification
NTP Carcinogen Studies




3
Some evidence -
Clear evidence
mg/L
(mg/kg-d)"1
(mg/kg-d)-1







1999
2008






Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



45.5

Y/N
Y/N
mg/L
M/L
M/L










Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









National Toxicology Program TR-544



Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
    Dibromoacetonitrile (DBAN)
    CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 600 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBPICR




# PWSs/Sites
sampled





#with Detects





% PWSs/Sites
with detects
48.6




Mean value of
Detects
1.61




Maximum
value of
Detects
24




Median value of
Detects
1.2




90% of
Detects
3.1




99% of Detects

Ambient Water Occurrence Data
N AWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


HRL Ratios (HRL/DBP ICR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount Released



# Sam pies






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States



% Sam pies w/
Detects






Units
States
States
States
Minimum value of
Detects


Non-cancer: 14.7
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects














Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data


ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes



National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects


Units for Mag
data
Notes


Cancer:







Disinfection By-Product
Value
38
13
0.47

4.06E-07
9,600
48
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze







-------
Dibromomethane
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 601 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibromomethane
2611
74953
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.01







11.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988




Critical Effect



increased carboxyhemoglobin







Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - dehydrogenases; plasma
urea and mild histological changes




Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
NCHRL/NCODR1 90%: 10.9
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1987; Basis NOAEL, UF= 1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 41,515,1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



70

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dibromomethane
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 602 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

16,549
23,006


60
108


0.363
0.469


0.1
0.00055


21.1
16.2


1.4
1.1


6.4
5.3


21.1
16

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
Krasner, et al.
HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,308

# Sam pies


Amount
Released

0
24,935
n
PWSs/Sites/Sa
mples
11,883
12
5

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
16
1
0.116

% Samples with
detects


Number of
States

0
4
%
PWSs/Sites/Sam
pies with
detects
0.13
8.33
0.01

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
0.55

Non-cancer: 10.9
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.2

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
14

0.1

Median value of
Detects


0.1

90% of
Detects


0.2

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.895
ND
90% of
Detects
2.45

Units for Mag
data
ug/L
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Techno!. , 40, pp 71 75-71 85 (and related documentation).




Organic synthesis; solvent (HSDB)
Value
15 days
23.7
1.7

0.000822
11,900
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slowly







-------
Dibutyltin dichloride
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 603 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibutyltin dichloride
9364
683181
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL-Int
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value




0.005






2.5
5


0.05
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date




2003






1977




Critical Effect




depressed humoral response against SRBC






mmunological Includ ng Allergic - decrease in humoral
immune response
Complete resorption of implanted embryos, increased
incidence of post implantation loss, cleft jaw, decreased
weight gain.


Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 4-week oral study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year42,213,1977
Supplemental Data; Toxicol letters 58:347-356, 1991


85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1248,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Dibutyltin dichloride
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 604 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; polymer intermediate; chemical intermediate (HSDB)
Value

1.56



92

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Dibutyltin oxide
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 605 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dibutyltin oxide
9781
818086
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0,171



44.9
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1977




Critical Effect











Behavioral -alteration of classical conditioning, Blood •
normocytic anemia, Blood -changes in erythrocyte
(RBC) count




Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (VYOMezhdunarodnayaKniga, 113095 Moscow, USSR) V,1- 1936-
Volume(issueXpage/year 42(4), 14, 1977, 26-week, rodent-rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.4

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dibutyltin oxide
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 606 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial Chemical (EPA/SRS)
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Dichloran
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 607 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dichloran
4022
99309
Attribute Scores
Potency Severity
5 7
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025










74.8



1,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1968




Critical Effect
ncreased alkaline phosphatase & cholesterol,
increased liver weights, hepatocyte hypertrophy,
vacuolar alterations of the brain and spinal cord,
prostate atrophy, degeneration of the seminiferous
tubules, & hypospermia in the epididymides










Liver - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels -
transaminases, Related to Chronic Data - death



Details of toxic effects not reported other than lethal dose
value

3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/SW Chronic EEC: 97.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve
Pharmacology. (Academic Press, Inc.
Volume(issue)/page/year 1 2,31 4,1 968
; 2 year dog study; TXAPA9 Toxicology and Applied
1 E. First St., Duluth, MN 55802) V.1- 1959-
Supplemental Data


rodent-guinea pig; PCOC Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year -,343,1966
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



175

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dichloran
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
    August 2009
Page 608 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total

CAL DHS


# Sam pies


Amount
Released
188,683
0
0
n
PWSs/Sites/Sa
mples
11
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States
2
0
0
%
PWSs/Sites/Sam
pies with
detects
0


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected


Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 1 .8 ug/L
Non-cancer: 97.2
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 1 .3 ug/L
Cancer:







Fungicide; in dyes (HSDB)
Value





6.3
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Dichloroacetaldehyde
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 609 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroacetaldehyde
2854
79027
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification





M
mg/L
(mg/kg-d)"1
(mg/kg-d)"1















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N
mg/L
W/L
W/L










Prevalence Magnitude
10 6
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; M = Medium probability of being carcinogenic



Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dichloroacetaldehyde
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 61 Oof 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al. and related documentation

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released


n
PWSs/Sites/Sa
mples
12




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12




Number of
States


%
PWSs/Sites/Sam
pies with
detects
100




Units
States
States
States
Minimum value of
Detects
ND

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year


Maximum
value of
Detects
14










Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
1

90% of
Detects


Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 71 75-7185 (and related documentation).

Cancer:







Disinfection By-Product
Value
38
4.3
0.27

8.40E-06
140,000
52
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation







-------
Dichloroacetonitrile (DCAN)
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 611 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroacetonitrile (DCAN)
14263
3018120
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1






1999





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N
mg/L
W/L
W/L






Teratogen



Prevalence Magnitude
10 7
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dichloroacetonitrile (DCAN)
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 612 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF ICR




# PWSs/Sites
sampled





#with Detects





% PWSs/Sites
with detects
70.1




Mean value of
Detects
2.59




Maximum
value of
Detects
24.6




Median value of
Detects
1.97




90% of
Detects





99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al. and related documentation

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released



n
PWSs/Sites/Sa
mples
12






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12






Number of
States



/o
PWSs/Sites/Sam
pies with
detects
100






Units
States
States
States
Minimum value of
Detects
ND

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year



Maximum
value of
Detects
12
















Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes



National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects
1

90% of
Detects


Units for Mag
data
ug/L

Cancer:



Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 7175-7185 (and related documentation).





Disinfection By-Product
Value
38
13
0.29

3.79E-06
33,500
51
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation. Note: may hydrolyze







-------
Dichloroiodomethane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 613 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Dichloroiodomethane
8286
594047
Attribute Scores
Potency Severity

Prevalence Magnitude
10 5
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
DSSTOX Carcinogen Classification





M
mg/L
(mg/kg-d)-1
(mg/kg-d)-1















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N
mg/L
W/L
W/L










3-model Categorical Prediction

HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data









DSSTOX; M = Medium probability of being carcinogenic



Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dichloroiodomethane
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 614 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Krasner, et al., (and related
documentation)

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released


n
PWSs/Sites/Sa
mples
12





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
12





Number of
States


/o
PWSs/Sites/Sam
pies with
detects
100





Units
States
States
States
Minimum value of
Detects


Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year


Maximum
value of
Detects
11













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
0.3

90% of
Detects


Units for Mag
data
ug/L
Notes
Finished drinking water monitoring; Krasner, et al, 2006. Env. Sci.
Technol., 40, pp 7175-7185 (and related documentation).

Cancer:







Disinfection By-Product
Value
38

2.03



33
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation







-------
Dichlorvos
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 615 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dichlorvos
2444
62737
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0005

0.0005
0.0005
0.004





0.625




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1993

1990
1997
1993










Critical Effect

Cholinesterase inhibit on

Plasma and RBC ChE inhibition; blood
Neurol.






Brain and Coverings - other degeneratve changes,
Kidney, Ureter, Bladder - urine volume increased,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - true Cholinesterase




Prevalence Magnitude ,,
1 1
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, AMVAC Chemical Corporation, 1990, NOAEL, dog, UF=100; Basis NOAEL = 0.05
mq/kq-d
Reference Dose
Reference Dose, AMVAC Chemical Corporation, 1990, NOAEL/LOAEL, dog, UF=100
Minimal Risk Level; UF = 100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day dog study; NYZZA3 Nippon Yakuzaishikai Zasshi.
Journal of the Japan Pharmaceutical Association. (Nippon Yakuznishikai, 2-1 2-1 5 Shibuya, Shibuya-ku,
Tokyo 150, Japan) V.1- 1949- Volume(issue)/page/year 26,739,1974
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 1014
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.01
0.29
0.41

B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1






1989
1991




Gl, pancreas, leukemia

IRIS



NTP, 1986
Vol. 53
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.1
Y/N
Y/N

W/L
W/L






Teratogen list



EPA, RAISHE, OEHHA, IARC, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dichlorvos

    CCL 3 Contaminant Information Sheet
OCCURRENCE DATAT
                                                                                                 EPA-OGWDW
    August 2009
Page 616 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP
PPMP

CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released

0
264
n
PWSs/Sites/Sa
mples


n
PWSs/Sites/Sa
mples
107

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0
0
#with Detects


% Samples with
detects
0
0
Number of
States

0
3
/O
PWSs/Sites/Sam
pies with
detects
0
0
%
PWSs/Sites/Sam
pies with
detects
0

Minimum value of
Detects
Not Detected
Not Detected
Units
States
States
States
Minimum value of
Detects
0
0
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects
Not Detected
Not Detected
Year
1997
2004
2004
Maximum
value of
Detects
0
0
Maximum
value of
Detects
Not Detected

Median value of
Detects
Not Detected
Not Detected

90% of
Detects
Not Detected
Not Detected

99% of Detects
Not Detected
Not Detected
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0
0
Median value of
Detects
Not Detected
99% of
Detects
0
0
90% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
Pesticide Pilot Mentoring Program (USGS/EPA) 9002(GC/MS); Ambient
Pesticide Pilot Mentoring Program (USGS/EPA)9002(GC/MS); Finished
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Insecticide; veter nary medicine (HSDB)
Value
<1 -3. 5 days
40.2
1.47

5.75E-07
8,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Dicofol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 617 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dicofol
5106
115322
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0012




0.002





22.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001




Critical Effect
Adrenal effect: Inhibition of adrenal cortical trophic
hormone (ACTH), stimulated release of cortisol










Related to Chronic Data - death




Prevalence Magnitude
10 6
HRL Ratio(s)
NCHRL/SW Chronic EEC: 16.8
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; one year dog study; HBPTO Handbook of pesticide toxicology.
Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1342,2001
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



8.4

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dicofol
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
    August 2009
Page 618 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS



# Sam pies

Amount
Released
786,805
0
33
n
PWSs/Sites/Sa
mples
21
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States
36
0
2
/O
PWSs/Sites/Sam
pies with
detects
0



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected



Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.5 ug/L
Non-cancer: 16.8
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.069 ug/L
Cancer:







nsecticide; (HSDB)
Value

10,500
5.02

2.42E-07
0.8
3
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Dicyclopentadiene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 619 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dicyclopentadiene
2762
77736
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.03





100

1



190
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1987







1986




Critical Effect



None observed





reproductive/developmental

Behavioral - alteration of classical conditioning,
Biochemical - Enzyme inhibition, induction, or change in
blood or tissue levels - multiple enzyme effects



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
9 8 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, NOEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year51(2),77,1986
Supplemental Data


mouse study; 40QBA3 "Proceedings of the International Congress on Toxicology, Toxicology as a
Predictive Science, 1st, Toronto, 1977," Plaa, G.L., and W.A. Duncan, eds., New York, Academic Press,
nc., 1978 Volume(issue)/paqe/year-, 448, 1978
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dicyclopentadiene
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 620 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

5,234
392,668
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

4
22
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in flame retardants; animal repellant (HSDB)
Value
15 days
1,800
3.16

6.26E-02
51.9
75
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Dieldrin
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 621 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dieldrin
2415
60571
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00005
0.00005
0.00005
0.00005
0.0001

0.0001



0.0083




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988


2000
1994

2000



1973




Critical Effect

rritability, tremors, occasional convulsions. Increased
absolute & relative liver weights. Liver parenchyma cell
changes including focal proliferation & focal hyperplasia

iver
iver






Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Immunological Including Allergic - decrease
in humoral immune response, Biochemical - Metabolism
(Intermediary) - other proteins
iver



Prevalence Magnitude , „ ,
36 L' L
HRL Ratio(s)
NC HRL/NCOD R2 90% : 0.8
CAR HRL/NCOD R2 90% : 4.5
Notes
Reference Dose
Reference Dose; Walker et al., 1969, Basis NOAEL = 0.005 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, Walker et al., 1969, Basis NOAEL/LOAEL, rat, UF=100
Minimal Risk Level, Walker et al., 1969, Basis NOAEL = 0.005 mg/kg-d, rat, UF=100
Acceptable Daily Intake; combined total Aldrin + Dieldrin; see also Aldrin
Acceptable Daily Intake
Tolerable Daily Intake; Fitzhugh et al., 1964; Treon & Cleaveland, 1955, Basis LOAEL = 0.025 mg/kg-d;
UF = 250; rat and dog study
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rabbit study; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 10,42,1973
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
16
16

B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1







1987






IRIS




Vol. 5, Suppl 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.002
0.35
0.002
Y/N
Y/N

W/L
W/L






teratogen list



CACART; EPA; RAISHE; OEHHA
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dieldrin
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                 EPA-OGWDW
    August 2009
Page 622 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


1 1 ,843



21



0.177



0.02



4.4



0.5



4.4



4.4

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP
PPMP

CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,100
85
# Sam pies


Amount
Released



n
PWSs/Sites/Sa
mples


# Sites
5,212
205
4
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1
0
#with Detects
4
2.89
4.70
% Samples with
detects


Number of
States



%
PWSs/Sites/Sam
pies with
detects
0.3
0
% Sites with
detects
0.08
0.001

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects


Minimum value of
Detects
0.01
Non-cancer: 0.8
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



5.60

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Maximum
value of
Detects
7
0.0097
0.180
Median value of
Detects


0.034

90% of
Detects


2.48

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Median value of
Detects
0.0225
99% of
Detects


90% of
Detects
4.91
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer: 4.5



Notes
Pesticide Pilot Mentoring Program (USGS/EPA) Ambient
Pesticide Pilot Mentoring Program (USGS/EPA) Finished
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Restricted insecticide (HSDB)
Value

10,600
5.2

1.00E-05
0.25

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DST






Notes
DST = Degrades sometimes/recalcitrant (HSDB)







-------
Diethanolamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 623 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethanolamine
4937
111422
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
10 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










20





Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










changes in liver and kidney weights






3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP information from HSDB, NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







2000











Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diethanolamine
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 624 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

55,403
1,396,761
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

14
29
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate; in cutting oi s and PPCPs; in
Value

4
-1.43


1,000,000
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF/BFA/BSA











Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ubricant production (HSDB)
Notes
BF = Biodegrades fast/BFA = Biodegrades fast with acclimation/BSA = Biodegrades slow with acclimation (BIODEG)







-------
Diethyl sulfate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 625 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethyl sulfate
2468
64675
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















647
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 5 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear PB214-270
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1







1999











Vol. 54, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y



Y/N
Y/N

M8/L
W/L






Teratogen list



IARC, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Diethyl sulfate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 626 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
10,644
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
6
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1.7 hours

1.14


7,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Chemical intermediate (HSDB)
DF = Degrades fast (HSDB)







-------
Diethylbenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 627 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylbenzene
28613
25340174
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.643



3,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date











1975



1975
Critical Effect











Vascular- regional or general arteriolar or venous
dilation, Liver - other changes, Blood - changes in
serum composition e.g. TP, bilirubin, cholesterol)



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(6), 90,1 975; 6-wk rabbit study
Supplemental Data


rabbit study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 40(6), 90,1975
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.50

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Diethylbenzene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 628 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






ndustrial chemical (EPA/SRS)
Value
1 5 days

4.07

0.021
31.9
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Diethylene glycol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 629 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylene glyco
4941
111466
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value






0.1



1,250
375



2,300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1937




Critical Effect










Maternal toxicity; increases in absolute and relative
kidney weights
Related to Chronic Data - death



Brain and Coverings - other degeneratve changes, Liver -
other changes, Kidney, Ureter, Bladder - other changes
Prevalence Magnitude , „
9 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information available; scored on CTDJPN NOEL.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP study TER89001
Lowest Observed Adverse Effect Level; 7 week rat study; JAMAAP JAMA, Journal of the American
Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883-
Volume(issue)/page/vear 1 09, 1 51 7, 1 937
Supplemental Data


Mouse study; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,145,1984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

8,750

Y/N
Y/N

W/L
W/L






teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Diethylene glycol
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 630 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; humectant; antifreeze; in PPCPs (HSDB)
Value

1
1.47

2.00E-09
1,000,000
35
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Diethylene glycol monobutyl eth
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 631 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylene glyco monobutyl ether
5022
112345
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.01












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



hematological effects












Prevalence Magnitude „,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Hobson et al.r 1987, NOAELJADJ, rat, UF=3,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



70

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diethylene glycol monobutyl eth
    CCL 3 Contaminant Information Sheet
                                                                                                 EPA-OGWDW
    August 2009
Page 632 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; chemical intermediate; industrial so vent (HSDB)
Value

10
0.56

4.45E-11
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Diethylenetriamine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 633 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethylenetriamine
4935
111400
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











10



1,080
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1372




Critical Effect











Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels -transaminases



Behavioral - convulsions or effect on seizure threshold
Prevalence Magnitude
8 5 NU
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 37(7),103,1 972, LOAEL, 26 week rabbit study
Supplemental Data


AMIHABAMA Archives of Industrial Health. (Ch cago, IL) V.11-21, 1955-60. For publisher information,
see AEHLAU. Volume(issue)/page/year 17,129,1958
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



23

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diethylenetriamine
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 634 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
u

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; industrial solvent; chelating agent (HSDB)
Value


-2.13

3.15E-07
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Diethyltoluenediamine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 635 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diethyltoluenediamine
51017
68479981
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















472
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral - somno ence (general depressed activity),
Musculoskeletal - other changes
3-model Categorical Prediction
NL?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issuej/page/year OTS0537598, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diethyltoluenediamine
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 636 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial Chemical (EPA/SRS)
Value
38 days





20
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Difenzoquat methyl sulfate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 637 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Difenzoquat methyl sulfate
34821
43222486
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.2
0.08

0.08






25
40
40


206
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1983




Critical Effect
Decreased body weight gain
Decreased body weight

Decreased weight







Blood - pigmented or nucleated red blood cells, Blood -
changes in serum composition (e.g. TP, bilirubin,
cholesterol), Liver - other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, „
8 6 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, American Cyanamide Co., 1975, Basis NOEL=25 mg/kg-d, rat, UF=300
Reference Dose
Reference Dose, American Cyanamide Co., 1975, Basis NOEL, LEL, rat, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; KHZDAN Khigiena i Zdraveopazvane.
Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V. 9- 1966- Volume(issue)/page/year
29(6), 42,1983
Supplemental Data


rat study; KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia,
Bulgaria) V.9- 1966- Volume(issue)/page/year 29(6), 42,1983
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,400

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Difenzoquat methyl sulfate
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 638 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
346,308


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
11


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (ChemlDPIus)
Value

118,000
-0.02


5,553

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Diglycidyl resorcinol ether
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 639 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diglycidyl resorcinol ether
4212
101906
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











143
12



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1986




Critical Effect











Related to Chronic Data - death
Decreased survival in males. (Cancer results positive in
both sexes mice and rats).



Prevalence Magnitude
1 1 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rat study; NTPTR National Toxicology Program
Technical Report Series. (Research Triangle Park, NC 27709) No. 206- Volume(issue)/page/year NTP-
TR-257,1986
Supplemental Data; NTP Rep # 257



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


1.7


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-'
(mg/kg-d)"1







1999











Vol. 36, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


334
0.021
Y/N
Y/N

W/L
W/L










OEHHA; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Diglycidyl resorcinol ether
    CCL 3 Contaminant Information Sheet
                                                                                                 EPA-OGWDW
    August 2009
Page 640 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
1
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n resins; rubber additive (HSDB)
Value
38 days

1.23



38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Dimethyl hydrogen phosphite
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 641 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl hydrogen phosphite
9953
868859
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












50



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












noneoplastic lesions of the lungs (rats) - Testicular
atrophy in male mice at a dose of 100 mg/kg Clear
evidence of cancer in male rats, equivocal evidence in
female rats and no evidence in mice



Prevalence Magnitude „,, „
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27T09) No.206- Volume(issue)/page/year NTP-TR-287,1985



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol. 48, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



117

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dimethyl hydrogen phosphite
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 642 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10K-500K
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n lubricants; flame retardant; chemcal intermediate (HSDB)
Value
1 9 days




>1 00,000
46
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DS






Notes
DS = Degrades slow (HSDB)







-------
Dimethyl laurylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 643 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl laurylamine
5006
112185
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













740


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date
















Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1322


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dimethyl laurylamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 644 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units

Cancer:



Notes





Chemical intermed ate; corrosion nhibitor (HSDB)
Value
15
21,700
5.4

0.0049

11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Dimethyl sulfate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 645 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl sulfate
2767
77781
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















140
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1979
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 5 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GTPZAB Qigiena Truda i Professional' nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 23(3),28,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




B2
2A
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1






1988
1999











Vol. 4, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y



Y/N
Y/N

M8/L
W/L






Teratogen list



EPA, IARC, CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Dimethyl sulfate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 646 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
10,221
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
11
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; former war gas (HSDB)
Value
1.2 hours
24.2
0.16

4.01 E-06
28,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Dimethyl terephthalate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 647 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyl terephthalate
5339
120616
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1







588
125



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1985









1973




Critical Effect

Chronic kidney inflammation

kidney; chronic inflammation







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude , 0
10 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NCI, 1979, Basis LOAEL = 125 mg/kg-d, rat, UF=1,000
Reference Dose
Reference Dose, NCI, 1979 , LOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 14 week rat study; AIHAAP American Industrial Hygiene
Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
Volume(issue)/page/year34,455,1973
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dimethyl terephthalate
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 648 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value
1 5 days
36.3
2.25

0.000134
19

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Dimethylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 649 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethylamine
5570
124403
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0,347



240
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1967




Critical Effect











Behavioral - alteration of classical conditioning, Liver -
changesin liver weight, Immunological Including
Allergic -decrease in cellular immune response



Behavioral - excitement, Behavioral - muscle weakness,
Gastrointestinal - ulceration or bleeding from stomach
Prevalence Magnitude
10 8
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, QISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/0 Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(6), 12,1967, 35 week rat study
Supplemental Data


rabbit and guinea pig studies; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year 32(6), 329,1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.81

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dimethylamine
    CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 650 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

25,286
618,880
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

7
26
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rubber additive; chemical intermed ate; fuel additive; photographic chemical (HSDB)
Value

435
-0.38



49
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Dimethyldichlorosilane
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 651 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyldichlorosilane
2681
75785
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













800


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude ,
9 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G. D. and F. E. Clayton (eds.). Pattys Industrial Hygiene and Toxicology: Volume 2A, 2B,
2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2398


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dimethyldichlorosilane
    CCL 3 Contaminant Information Sheet
                                                                                                 EPA-OGWDW
    August 2009
Page 652 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; laboratory chemical (HSDB)
Value
1 5 days

2.24

0.019
1,120
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Dimethyltin dichloride
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 653 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dimethyltin dichloride
9560
753731
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Supplemental LD50
Value















73.9
14
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
mg/kg
Date















1973
1986
Critical Effect















Details of toxic effects not reported other than lethal dose
value
Neurological damamge to the brain
Prevalence Magnitude
6
Incomplete data for scoring HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


rodent-rat; TRIPA7 Tin Research Institute, Publication. (Middlesex, UK) 1934-76. For publisher
nformation, see IRIPDP. Volume(issue)/page/year -,1,1973
Aldridgeetal, 1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dimethyltin dichloride
    CCL 3 Contaminant Information Sheet
                                                                                                 EPA-OGWDW
    August 2009
Page 654 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n plastics, food packaging, plastics, pesticides and pa nts (organotins)
Value


-1.06


20,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Dinitrotoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 655 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dinitrotoluene
28581
25321146
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002









0.025




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1977




Critical Effect

Weakness, ataxia, tremors, and neurotoxicity









Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
esterases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other oxidoreductases




Prevalence Magnitude „,, „ , „
2 4 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 42(1 0) , 1 7, 1 977
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10J
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.005
0.68


B2

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






19990





Liver, mammary gland

EPAHA





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

14
0.05
Y/N
Y/N

W/L
W/L






teratogen list



EPA, RAISHE
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dinitrotoluene
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 656 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

13
6,802
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; plasticizer (HSDB)
Value
38 days
372
2.18

3.96E-07
270
21
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Diphenylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 657 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diphenylamine
5436
122394
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03
0.025

0.025

0.08




2.5
0.833



300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999




Critical Effect
Alterations in clinical chemistry parameters. Increased
absolute & relative kidney, liver & spleen weights


Decreased body weight gain, increased liver and kidney
weights







Gastrointestinal - alteration in gastric secretion, Kidney,
Ureter, Bladder - changes in tubules (including acute renal
failure, acute tubular necrosis), Kidney, Ureter, Bladder -
proteinuria



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
88 '
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Thomas et al., 1967, Basis NOEL=2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose, Thomas et al., 1967, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30 day rat study
Supplemental Data


guinea pig study; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C1 12,1 991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

210

Y/N
Y/N

W/L
W/L






teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Diphenylamine
    CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 658 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

97
414,131
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

3
15
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide/herbicide; polymer stab lizer; rubber additve; topical veterinary agent (HSDB)
Value

1,887
3.5

3.40E-06
53

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Dipropylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 659 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dipropylamine
6158
142847
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











5



300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1970




Critical Effect











Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - catalases



Behavioral - changes in motor activity (specific assay),
Behavioral - muscle weakness
Prevalence Magnitude Kll 0
6 7 NL"
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 35(4),103,1970, 26 week rat and rabbit study
Supplemental Data


rat study; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0544865
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



11.7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dipropylamine
    CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 660 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days
190
1.67


35,100
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Dipropylene glycol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 661 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dipropylene glycol
28536
25265718
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










6,200


14.8

14,850
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mL/kg
mg/kg
mg/kg
Date
















Critical Effect










Kidney lesions




Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 7 NU
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, SIDS Summary
Lowest Observed Adverse Effect Level
Supplemental Data
Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley
and Sons, 1978-1984., p. 11 (1980) 936

rodent-rat; 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press,
nc., 1969 Volume(issue)/page/year -, 731, 1969
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



43,400

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dipropylene glycol
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 662 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; antifreeze; in PPCPs; medication (HSDB)
Value

1
0.64

5.60E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Diquat
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 663 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Diquat
13896
2764729
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.005




0.002









30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Lens opacities cataracts decreased organ weights
epidymusadenals














Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain
Prevalence Magnitude
10 5
HRL Ratio(s)
NC HRL/CAL DHS 90% : 0.3
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake; as diquat ion
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME
04046) V.1- 1944- Volume(issue)/page/year 27,51,1970
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC
WHOWQ

Y

35

0.07
10
Y/N
Y/N

W/L
W/L
mg/L
Mg/L








teratogen list






UMD
Drinking Water Equivalent Level



Provisional Guideline value
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Diquat
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 664 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS



# Sam pies

Amount
Released
266,858


n
PWSs/Sites/Sa
mples
4,867
OPP Estimated Environmental Concentration
HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
9



% Samples with
detects

Number of
States
28


%
PWSs/Sites/Sam
pies with
detects
0.18



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.08



Maximum
value of
Detects

Year
1997


Maximum
value of
Detects
549
Surface water chronic: 0.4 ug/L
Non-cancer: 0.3
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
4.9
90% of
Detects
115
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.006 ug/L
Cancer:







Herbicide (for diquat dibromide, CASRN 85-00-7)
Value
15
2,000
-4.6

1.40E-13
708,000
20
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)
For diquat dibromide
For diquat dibromide

For diquat dibromide
For diquat dibromide


-------
Disodium iminodiacetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 665 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Disodium iminodiacetate
10140
928723
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















8,070
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1972
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , 0 ,
97 L" L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut
Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
Volume(issue)/page/year -,128,1972, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Disodium iminodiacetate
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 666 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>500M-1 B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial Chemical (EPA/SRS)
Value
1 5 days





39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Dodecylbenzenesulfonic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 667 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dodecylbenzenesulfonic acid
29930
27176870
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















650
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
85 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger PI. 3, D-1000 Berlin 33, Fed. Rep.
Ger.) V.32- 1974- VoIume(issueXpage/year 32,245,1974, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Dodecylbenzenesulfonic acid
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 668 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Laboratory chem cal; fungicide stabilizer; in electron cs cleaners (HSDB)
Value
1 5 days

4.78

6.27E-08
0.703
ir
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Dodine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 669 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Dodine
13332
2439103
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02
0.004

0.004

0.1




1.25
48



176
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987



2000





1961




Critical Effect
Body weight loss
Thyroid









Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
10 5 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose, American Cyanamid, 1958
Reference Dose, American Cyanamid, 1958, Bass NOEL = 1.25 mg/kg-d, dog, UF=300
Reference Dose
Reference Dose; American Cyanamid, 1958, UF=300, dog
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2 year rat study; TXAPA9 Toxicology and Applied Pharmacology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year
3,127,1961
Supplemental Data


rodent-guinea pig; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year-, 64,1 982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Dodine
    CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 670 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
151,538


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
28


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fungicide (HSDB)
Value
15 days
15,500
1.32

6.02E-19
630
31
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Endosulfan
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 671 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Endosulfan
5104
115297
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.006
0.006

0.006
0.002
0.006










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1994


2000











Critical Effect
Reduced body weight gain, enlarged kidneys,
increased incidences of marked progressive
glomerulonephrosis, & blood vessel aneurysms
red. body weight gain, glomerular nephrosis

red body weight, increased marked progressive
glomrulonephrosis
hepatic; liver











Prevalence Magnitude , „
10 7 L'
HRL Ratio(s)
NC HRL/SW Chronic EEC: 28
Notes
Reference Dose
Reference Dose; Basis NOAEL = 0.7 female and 0.6 male mg/kg-d, Hoechst, 1989a; UF=100
Reference Dose
Reference Dose, Hoechst Celanese Corp. 1989, NOAEL/LOAEL, rat, UF=100
Minimal Risk Level, Hoechst, 1989c, Basis NOAEL = 0.18 mg/kg-d, dog, UF=100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

42

Y/N
Y/N

W/L
W/L






teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Endosulfan
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA
                                                                                                EPA-OGWDW
    August 2009
Page 672 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

# Sam pies


Amount
Released
1,601,195



OPP Estimated Environmental Concentration

HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

#with Detects


Units
Ibsfyr
Ibs/yr
Ibs/yr


% Samples with
detects


Number of
States
44




Minimum value of
Detects


Units
States
States
States


Maximum
value of
Detects


Year
1997
2004
2004

Surface water chronic: 1 .5 ug/L

Non-cancer: 28
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes







Ground water chronic: 0.01 2 ug/L

Cancer:







nsecticide (HSDB)
Value

22,000
3.83

6.51 E-05
0.45
5
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
EPIC
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 673 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
EPTC
9581
759944
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.025

0.025






2.5




112
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987













1971
Critical Effect

Degenerative cardiomyopathy

Degenerative cardiomyopathy











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, PPG Industries, 1986a, Basis NOEL = 2.5 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, PPG Industries, 1986, NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


mammal- cat; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA)
1964-71. Discontinued. Volume(ssue)/page/year 36(1-3), 196, 1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


175

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   EPIC
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 674 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,621


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118

# Sam pies

Amount
Released
8,791,984
12
1,204
n
PWSs/Sites/Sa
mples
115
12
2,243
406

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



5.7

% Samples with
detects

Number of
States
42
3
3
%
PWSs/Sites/Sam
pies with
detects

5.3
0
Not Detected

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Not Detected
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



40

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

0.03
Not Detected
0.01

Median value of
Detects

0.086

90% of
Detects

1.5

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
99% of
Detects


Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Cancer:



Notes
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Herbicide (HSDB)
Value
38 days
258
3.21

1.59E-05
375
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Esfenvalerate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 675 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Esfenvalerate
42403
66230044
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02














325
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Maternal toxicity - abnormal gait and mobility














Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
NC HRL/SW Chronic EEC: 26.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


rodent-rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH
44094) Volume(issue)/page/year -,C287,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Esfenvalerate
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 676 of 1124
OCCURRENCE DATA

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies


Amount
Released
228,885



OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects


Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects


Number of
States
47





Minimum value of
Detects


Units
States
States
States



Maximum
value of
Detects


Year
1997
2004
2004

Surface water chronic: 5.3 ug/L
Non-cancer: 26.4
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes




Ground water chronic: 0.009 ug/L
Cancer:







nsecticide; medication (HSDB)
Value
16. 3 days
100,000-398,000



<1
2
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DFA






Notes
DFA = Degrades slow with acclimation (HSDB)







-------
Estragole
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 677 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Estragole
6041
140670
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








10






1,230
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect








decreased body weight, increased liver weight
increased liver enzymes, hematoloficla effects






Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,,
5 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data, RfD eq, Smith et al 2002, Adbo et al abstract
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


rodent-rat; FCTXAV Food and Cosmetics Toxicoogy. (London, UK) V. 1-19, 1963-81. For publisher
nformation, see FCTOD7. Volume(issue)/page/year 14,603,1976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70,000

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Estragole
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 678 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flavoring agent; n PPCPs (HSDB)
Value
38 days

3.47


178
12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Ethanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 679 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethanol
2462
64175
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1.43
100


3,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1976




Critical Effect











Behavioral - changes in motor activity (specific assay),
Behavioral - ataxia, Behavioral - antipsychotic



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, JPETAB Journal of Pharmacology and Experimental
Therapeutics. (Williams & Wllkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year 197,488,1976; human study
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)


Rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 32(3), 31, 1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3.34

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Ethanol
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                                EPA-OGWDW
    August 2009
Page 680 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



n
PWSs/Sites/Sa
mples
2



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



%
PWSs/Sites/Sam
pies with
detects
0



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected
Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected



Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Pesticide; beverage/food additive; medication; solvent (HSDB); gasoline additive
Value

1
-0.31

5.00E-06
1,000,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Ethephon
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 681 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethephon
25550
16672870
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.018
0.005

0.005

0.05





1,250




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1983




Critical Effect
Diarrhea, urinary & bowel movements urgency,
stomach cramps
Plasma cholinesterase inhibition

blood







Brain and Coverings - recordings from specific areas of
CNS, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Related to Chronic Data - death




Prevalence Magnitude
10 8
HRL Ratio(s)
NCHRL/SW Chronic EEC: 18.8
Notes
Reference Dose
Reference Dose, Union Carbide, 1977a, Basis LEL, human, UF=100
Reference Dose
Reference Dose; Union Carbide, 1977, Basis LEL, human, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 8 week rat study; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 48(8), 79,1 983
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



126

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Ethephon
    CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 682 of 1124
OCCURRENCE DATA

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

# Sam pies


Amount
Released
5,407,986



OPP Estimated Environmental Concentration
HRL Ratios (HRL/SW Chronic EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

#with Detects


Units
Ibsfyr
Ibs/yr
Ibs/yr


% Samples with
detects


Number of
States
32




Minimum value of
Detects


Units
States
States
States


Maximum
value of
Detects


Year
1997
2004
2004

Surface water chronic: 6.7 ug/L
Non-cancer: 18.8
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes







Ground water chronic: 0.67 ug/L
Cancer:







Plant growth regulator (HSDB)
Value

3.57
0.05

5.70E-12
1,000,000
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Ethion
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 683 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Ethion
7949
563122
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0005
0.0005

0.0005
0.0004
0.002





0.5



13
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1989


2000
1990










Critical Effect
Plasma, RBC & brain ChE inhibition
Decreased body weight


Brain acetylcholinesterase inhibition






Blood - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - true
cholinesterase



Details of toxic effects not reported other than lethal dose
value
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)-1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3.5

Y/N
Y/N

W/L
W/L










Prevalence Magnitude , „
66 L
HRL Ratio(s)
NC HRL/SWC EEC: 0.53
Notes
Reference Dose; Basis = NOAEL 0.05 mg/kg-d; UF = 100.
Reference Dose; Basis = NOEL 0.05 mg/kg-d
Reference Dose
Reference Dose
Minimal Risk Level; Basis = NOAEL 0.06 mg/kg-d
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge
Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year 8,173,1988
Supplemental Data


PHJOAV Pharmaceutical Journa . (Pharmaceutcal Soc. of Great Britain, 1 Lambeth High St., London,
SE1 7JN, UK) V.131- 1933- Volume(issue)/page/year 185,361, 1960









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethion
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 684 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP ambient water
PPMP finished water



Amount
Released
504,535


n
PWSs/Sites/Sa
mples


OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects
0
0



Number of
States
2


%
PWSs/Sites/Sam
pies with
detects
0
0



Units
States
States
States
Minimum value of
Detects





Year
1997


Maximum
value of
Detects
Not Detected
Not Detected
Surface water chronic: 6.6 ug/L
Non-cancer: 0.53
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002












Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects


95% of
Detects
Not Detected
Not Detected
Units
ug/L
ug/L
Notes
Pesticide Pilot Montoring Program (USGS/EPA)

Ground water chronic: 0 ug/L
Cancer:







nsecticide (HSDB)
Value

13,200
5.07

9.56E-07
2
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation







-------
Ethyl acetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 685 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethyl acetate
6103
141786
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.9

0.9




25

900




4,100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986

1986












Critical Effect

Mortality & body weight loss

mortality and weight loss











Behavioral - somnolence (general depressed activity),
Behavioral - changes in motor activity (specific assay),
Behavioral - coma
Prevalence Magnitude , 0
8 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1986, Basis NOEL=900 mg/kg-d, rat, UF=1,000
Reference Dose
Reference Dose; UF = 1,000; USEPA1986; rat study
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


mouse study; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnay
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



6,300

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Ethyl acetate
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 686 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; food additive; solvent; medication (HSDB)
Value

6.13
0.73

0.000134
80,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Ethyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 687 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethyl acrylate
6050
140885
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











71.4




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Gastrointestinal - other changes




Prevalence Magnitude ,
9 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13 week rat study; NTIS National Technical Information Service.
(Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0540988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.048



2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999











Vol. 39, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


167
0.729
Y/N
Y/N

W/L
W/L










RAISHE; IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Ethyl acrylate
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 688 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

249
152,024
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

4
24
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer additive; former food and PPCP additive (HSDB)
Value

11.9
1.32

0.00034
15,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
Ethylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 689 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylamine
2620
75047
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











71.4

400


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Gastrointestinal - other changes

Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude ,
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year
OTS0540988
Supplemental Data
Lewin, F.J. Saxs, Dangerous Properties of Industiral Materials. 9th ed. Volumes 1-3. New York,
NY:Van Norstrand Reinhold, 1996., pi 1517, LD50, rat


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Ethylamine
    CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 690 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL/No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value

20
-0.13


1,000,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
Ethylene glycol monobutyl ether
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 691 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylene glyco monobutyl ether
4970
111762
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.5

0.5
0.07











Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1999


1998











Critical Effect

Changes in blood mean corpuscular volume (MCV)

changes in mean corpuscular volume












Prevalence Magnitude ,,, „
8 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; NT, 1993, BMD, rat, UF=10
Refernce Dose
Reference Dose.NTP, 1993, BMD, mouse, rat, UF=10
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3,500

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethylene glycol monobutyl ether
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 692 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n hydraulic fluids; industrial solvent; in PPCPs (HSDB)
Value

1
0.83

1.60E-06
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Ethylenediamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 693 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylenediamine
4594
107153
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.09












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



iverand kidney toxicity












Prevalence Magnitude , „
87 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Hermanskyet al 1999; Basis NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



630

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethylenediamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 694 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; ndustrial solvent; in prep of dyes, synthetic waxes, resins, insecticides; veterinary medicine (HSDB)
Value

24.7
-2.04

1.73E-09
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Ethylenediaminetetraacetic acid
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 695 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ethylenediaminetetraacetic acid
2393
60004
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










250




30
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1966




1991
Critical Effect










NOAEL without a LOAEL




Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,,,
67 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Oser et al. 1 966
Lowest Observed Adverse Effect Level
Supplemental Data


FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park,
Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year 29,845,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,750

Y/N
Y/N

W/L
W/L






Teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ethylenediaminetetraacetic acid
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 696 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; antioxidant; chelating agent; in PPCPs; veterinary medicine (HSDB)
Value

98
-3.86

7.70E-16
1,000
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Fenbutatin oxide
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 697 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fenbutatin oxide
22779
13356086
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.017




0.03





15



1,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2001



1991
Critical Effect
Decreased pup body weight gain










Blood - changes in leukocyte (WBC) count



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
95 L'
HRL Ratio(s)
No water data
Notes
Reference Dose; May 31 2002 certified letter to the registrant
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1219,2001
Supplemental Data


rodent, mouse; PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd.,
Thornton Heath CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,364,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



119

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Fenbutatin oxide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 698 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released
265,275
0
1,158
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States
23
0
1
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Acaricide (HSDB)
Value


5.2

2.00E-09
0.0127

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Ferbam
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 699 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ferbam
24121
14484641
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015




0.003





25




Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1956




Critical Effect
Developmental Neurotoxicity










Behavioral - convulsions or effect on seizure threshold,
Related to Chronic Data - death




Prevalence Magnitude , „ ,
9 6 L"L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose, OPP RED Fact Sheet RfD for Thiram
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Group ADI for Ferbam and Ziram
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in dog; JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 118,174,1956
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

105

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Ferbam
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 700 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

# Sam pies

Amount
Released
317,125
0
0

OPP Estimated Environmental Concentration

#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr


% Samples with
detects

Number of
States
24
0
0


Minimum value of
Detects

Units
States
States
States


Maximum
value of
Detects

Year
1997
2004
2004

Surface water chronic: 0 ug/L

Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Notes
Ground water chronic: 0 ug/L

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Cancer:







Fungicide (HSDB)
Value

300
-1.6


130

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
Fluometuron
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 701 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fluometuron
12839
2164172
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0055
0.013
0.01
0.013







100




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Decreased body weight gain and discoloration in the
spleen.
No adverse effects. Decreased Potency Score by one
nteger









Endocrine - changes n spleen weight, Blood - changes in
spleen, Nutritional and Gross Metabol c - weight loss or
decreased weight gain




Prevalence Magnitude , „ ,
95 L' L
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 19.25
CAR HRL/NAWQA AW 90% : 0.97
Notes
Reference Dose
Reference Dose, NCI, 1980, NOAEL 12.5, rat, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB80-21 7904
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification



0.018
c
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1

















OPP


Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

0.5
38.5
1.94
Y/N
Y/N
mg/L
M/L
M/L










EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Reative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
    Fluometuron
    CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 702 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
PPMP
PPMP

HRL Ratios (HRL/NAWQA AW 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,,2, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,600

^Samples

Amount
Released
5,313,290
1,736
1,776
n
PWSs/Sites/Sa
mples
345



130

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

24
19

2.83

% Samples with
detects

Number of
States
15
1
3
%
PWSs/Sites/Sam
pies with
detects

7.7
8.4

0.003

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.0018



Non-cancer: 19.25
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



37.8

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
0.0105
0.264
0.1

0.22

Median value of
Detects

2

90% of
Detects

8.34

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




95% of
Detects

0.145
0.062

Units for Mag
data
ug/L
ug/L
ug/L

Cancer: 0.97



Notes
Pesticide Data Program (USDA); 2002
Pesticide Pilot Monitoring Program (USGS/EPA) raw water,
9060(HPLC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) finished water,
9060(HPLC/MS)





Herbicide (HSDB)
Value

363
2.42

1.80E-09
110

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Fluoroacetic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 703 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fluoroacetic acid
6203
144490
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00002











0.468


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1996


Critical Effect

Increased heart weight, decreased testes weight and
spermatogenisis - Sodium salt This is essentially the
same as sodium fluoroacetate














Prevalence Magnitude , „ ,
5 5 Li~L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R. J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van
Nostrand Reinhold, 1996., p. 1671


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Fluoroacetic acid
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 704 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former rodenticide (HSDB)
Value

500
0.03


50
38
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Fomesafen
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 705 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fomesafen
62548
72178020
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
9 7

Critical Effect
















3-model Categorical Prediction
L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.19


C

mg/L
(mg/kg-d)1
(mg/kg-d)-1
(mg/kg-d)-1






1988





adenoma and carcinoma; liver





Huntingdon, 1985; mouse study

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.184
Y/N
Y/N

W/L
W/L










RAISHE; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Fomesafen
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 706 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
1,100,341
2,342
42,651
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
24
2
3
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (HSDB)
Value
6-12 months
11,000
2.9

7.54E-13
50

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (HSDB)







-------
Fonofos
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 707 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Fonofos
10236
944229
Attribute Scores
Potency Severity
6 5
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002
0.002
0.002












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986














Critical Effect

RBC ChE inhibition, cholinergic symptoms (tremors,
acrimation, salivation), increased liver weight

RBC ChE inhibition, cholinergic symptoms (tremors,
acrimation, salivation), increased liver weight












3-model Categorical Prediction
NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 31 1
Notes
Reference Dose
Reference Dose, Stauffer Chemical Co, 1969, NOEL 0.2, dog, UF=100
Reference Dose
Reference Dose, Stauffer Chem
cal Co, 1969, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.07
14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Fonofos
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 708 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,116


# Sam pies


Amount
Released
417,372


n
PWSs/Sites/Sa
mples
283
669
3

95


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

1
1.3

1.34


% Samples with
detects


Number of
States
33


/O
PWSs/Sites/Sam
pies with
detects

0.1


0.001


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

0.0075
0.04

Non-cancer: 311
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.2


Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects

0.0075


0.007


Median value of
Detects


0.045


90% of
Detects


0.21


99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



99% of
Detects



Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2002(GC/MS)

Cancer:







Restricted use insecticide; fumigant (HSDB)
Value
38 days
864
3.94

6.97E-06
15.7
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Formetanate hydrochloride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 709 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Formetanate hydrochloride
27710
23422539
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00065












18


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1979


Critical Effect
Cholinesterase inhibition in the pup brain















Prevalence Magnitude , „ ,
10 5 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 56.9
Notes
Reference Dose; IRED
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
mouse; Worthing, C. R. (ed.). Pesticide Manual. 6th ed. Worcestershire, England: British Crop Protection
Council, 1979., p. 284


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4.55

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Formetanate hydrochloride
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
    August 2009
Page 710 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies
Amount
Released
134,527


# PWSs/Sites
sampled
OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects
Number of
States
27


% PWSs/Sites
with detects


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects


Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
Surface water chronic: 0.08 ug/L

Non-cancer: 56.9
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
99% of
Detects
Units for Mag
data
Notes
Ground water chronic:

Cancer:







nsecticide (HSDB)
Value

3.2-212


2.30E-19
>500,000
42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Formic acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 711 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Formic acid
2463
64186
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



2







360



700
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1990







1921



1979
Critical Effect



Decreased growth







Behavioral - food intake (animal), Nutrtional and Gross
Metabolic - weight loss or decreased weight gain



Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude
10 10
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1-
1909/10- Volume(issue)/page/year 16,463,1921
Supplemental Data


rodent, mouse; GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For
publisher information, see MTPEEI Volume(issue)/page/year 23(12), 49, 1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14,000

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Formic acid
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 712 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

240,191
10,144,003
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

22
38
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; chemical intermediate; pesticide; in pa nt strippers (HSDB)
Value

1
-0.54

1.67E-07
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Furan
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 713 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furan
4814
110009
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.001

0.001







21.4




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987









1993




Critical Effect

Minimal to mild liver lesions. Increased relative liver
weight

iver







Liver - other changes, Liver - changes n liver weight,
Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude , „
68 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NTP, 1982, NOAEL 2, mouse, UF=1000
Reference Dose
Reference Dose, NTP, 1982, NOAEL/LOAEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in mouse; NTPTR National Toxicology
Program Techn cal Report Series. (Research Tr angle Park, NC 27709) No.206-
Volume(issue)/page/year NTP-TR-402,1993
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1



















Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7

Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Furan
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 714 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

89.7
1.34

0.00541
10,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (HSDB)







-------
Furfural
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 715 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furfural
3927
98011
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.003

0.003







53.6




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1990




Critical Effect

Mild hepatocellular vacuolization

iver







Liver - changes in liver weight




Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, NTP, 1981a, LOAEL 11, rat. UF=3000
Reference Dose
Reference Dose, NTP, 1981, LOAEL, rat. UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in mouse; NTPTR National Toxicology
Program Techn cal Report Series. (Research Tr angle Park, NC 27709) No.206-
Volume(issue)/page/year NTP-TR-382,1990
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



21

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Furfural
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 716 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; flavoring; chemical intermediate (HSDB)
Value

17.7
0.41

3.38E-06
77,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Furfuryl alcohol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 717 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Furfuryl alcohol
3826
96297
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









4

75



930
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Hematological effects, increase in spleen relative and
absolute weights.

Endocrine - changes in spleen weight, Blood - pigmented
or nucleated red blood cells, Blood - changes in
erythrocyte (RBC) count



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „,, 0
6 7 NL:
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientif c & Technical Information. Volume(issue)/page/year
OTS0524679; 13 week rat study
Supplemental Data


Rodent-rat; TSCAT Office of Tox c Substances Report. (U.S. Environmental Protection Agency, Office of
Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year OTS 513319
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



28

Y/N
Y/N

ug/L
ug/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Furfuryl alcohol
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 718 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Antioxidant (ChemlDPIus); Industr
Value


0.63

1.04E-05
100,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





al chemical (EPA/SRS)
Degradation
Code
BS






Notes
BS = Biodegrades s ow (BIODEG)







-------
gam ma-Butyrolactone
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 719 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
gam m a-Butyrolactone
3838
96480
Attribute Scores
Potency Severity
4 5
Prevalence Magnitude
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










175

262



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










Decreased respiration and activity in mice.

Hyperplasia of the adrenal medula (males) decreased
body weight gain (females). Cancer equivocal evidence
male mice. No evidence male or fema e rats and female
mice




3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP Report 406
Lowest Observed Adverse Effect Level
Supplemental Data; NTP Report 406



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1







1999











Vol. 11, Suppl. 7, Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,225

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   gam ma-Butyrolactone
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 720 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent in PPCPs (HSDB)
Value
1 5 days
7.1
-0.64

5.30E-08
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Glutaraldehyde
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 721 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glutaraldehyde
4927
111308
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.3




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987




Critical Effect











Liver - fatty liver degeneration, Nutritional and Gross
Metabolic - weight loss or decreased weight gain,
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - true cholinesterase




Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (VTO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue);pagefyear52(3),77,1987
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.7

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Glutaraldehyde
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 722 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; embalm ng fluid; chemical intermediate (HSDB)
Value


-0.18

1.10E-07
1,000,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Glycerine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 723 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glycerine
2289
56815
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











16
850


4,090
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











2000



1977
Critical Effect











Skin and Appendages - tumors, Tumorigenic - facilitates
action of known carcinogen
Ql tract: hyperaemia, petechial haemorrhage or
erosions (DR)


Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
8 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 25-week study in mouse. CALEDQ Cancer Letters (Shannon,
reland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
Volume(issue)/page/year 1 55,61 ,2000
Supplemental Data, SIDS


rodent, mouse; FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.3- 1930- Volume(issue)/page/year (6), 56,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,217

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Glycerine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 724 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; in PPCPs; food additive; in res ns (HSDB)
Value


-1.76

1.75E+11
1,220,000
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Glycidol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 725 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glycidol
7880
556525
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










19

150



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1990



Critical Effect










Effects on sperm count and testicular histopathology

Brain and Coverings - demyelination, Kidney, Ureter,
Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis) testicular atrophy, reduced
survival, Related to Chronic Data - death Clear evidence
of carcinogenicity in mice and rats 2 species and 2-sexes



Prevalence Magnitude
1 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; NTP
Lowest Observed Adverse Effect Level
Supplimental Data, NTPTR National Toxicology Program Technical Report Series. (Research Triangle
Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-374,1990



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1



















Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


133

Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Glycidol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 726 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; stabilizer (HSDB)
Value
1 5 days

-0.95

5.84E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Glyoxal
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 727 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Glyoxal
4600
107222
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value







0.2



297



200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991




Critical Effect







decreased body weight gain



Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - weight loss
or decreased weight gain, Biochemica - Enzyme
inhibition, induction, or change in blood or tissue levels -
other transferases



Behavioral - muscle weakness
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; IPCSCICAD2004
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 16,763,1991
Supplemental Data


rodent, rat; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informaton. Volume(issue)/page/year OTS0533618
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,400

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Glyoxal
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 728 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n textiles; chemical intermediate (HSDB)
Value
1 5 days
1
-1.66

3.33E-09
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
HCFC-133a
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 729 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
HCFC-133a
2690
75887
Attribute Scores
Potency Severity

Prevalence Magnitude
3 6
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction

HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol. 41,Suppl7, Vol71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   HCFC-133a
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 730 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

23
56,253
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
3
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Refrigerant; chemical intermediate (HSDB); gas
Value
38
30


0.27
9,200
47
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Heptane
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 731 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Heptane
6156
142825
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











2.86




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Liver -changes in liver weight




Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issueXpage;yearOTS0571116
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



6.67

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Heptane
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 732 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Gasoline standard; anesthetic, solvent, in organic synthesis (HSDB)
Value

275
4.66

2.00E+00
3.4

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Hexachlorobutadiene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 733 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexachlorobutadiene
3263
87683
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.0002
0.0002
0.0002


0.00034



2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







1996



1965




Critical Effect


ncrease in urinary coproporphyrin excretion &
increase in renal tubular epithelial
hyperplasiafproliferation
regeneration



kidney



Liver - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol), Immunological
ncluding Allergic - increase in cellular mmune response




Prevalence Magnitude , „
45 L'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 0.28
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, USEPA, 1993; Basis LOAEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, .Yangetal., 1989, NTP1991, BMLD(50), mouse, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-week oral study in guinea pig; GTPZAB Gigiena Truda i
Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year 9(1 11,50,1965
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.05
0.078


C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1.4

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexachlorobutadiene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 734 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,284
22,736


43
41


0.35
0.18


0.05
0.1


10
1.5


0.25
0.3


5
0.8


10
1.5

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,310

# Sam pies

Amount
Released

5
742
# PWSs/Sites
sampled

0

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0

% Samples with
detects

Number of
States

1
3
% PWSs/Sites
with detects

0.14

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.28
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

Not Detected

Median value of
Detects

Not Detected

90% of
Detects

Not Detected

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; chlorine gas scavenger; solvent; hydraulic fluids (HSDB)
Value

994
4.78

0.0103
3.2

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Hexachloroethane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 735 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexachloroethane
2514
67721
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.001
0.001
0.001
0.01











Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

Renal lesions, including renal atrophy, degeneration,
hypertrophy, & dilation

kidney, atrophy and degeneration of renal tubules












Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Referenc Dose, Gorzinski et al., 1985, NOAEL 1 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose.Gorzinski et al., 1985, NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.3
0.014
0.039

C
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7
3
Y/N
Y/N

W/L
W/L










CACART; EPA; RAISHE; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexachloroethane
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 736 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,618

# Sam pies

Amount
Released

5
1,015
# PWSs/Sites
sampled

0

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0

% Samples with
detects

Number of
States

1
8
% PWSs/Sites
with detects

0.05

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

Not Detected

Median value of
Detects

Not Detected

90% of
Detects

Not Detected

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame inhibitor/retardant; polymer additive; in organic synthesis (HSDB)
Value

10,600
5.2

1.00E-05
0.25

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Hexahydro-1,3,5-tris(2-hydroxye
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 737 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine
16177
4719044
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1.99
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value - Dermal sensitization
Prevalence Magnitude
6 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231)
Volume(issue)/page/year #3824309
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexahydro-1,3,5-tris(2-hydroxye
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 738 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Bacteriocide (ChemlDPIus)
Value
38 days





47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Hexahydroazepine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 739 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexahydroazepine
4944
111499
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










90




20.7
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










Some discomfort on dosing




Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Liver - other changes
Prevalence Magnitude ,,, _
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPPT Summary, NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data


Rodent, rat; NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Informat on. Volume(issue)/page/year OTS0534842
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



630

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexahydroazepine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 740 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days
170


6.10E-06
31,900
36
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Hexamethylene-1,6-diisocyanate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 741 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylene-1 ,6-diisocyanate
9801
822060
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















350
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
7 3 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data

Supplemental Data


LD50.TAKHAA Takeda Kenkyusho Ho. Journa of the Takeda Research Laboratories. (Takeda
Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970-
Volume(issue)/page/year 39,202,1980, rodent, mouse
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexamethylene-1,6-diisocyanate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 742 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer additive; adhesive; chemcal intermediate (HSDB)
Value

5,864
3.2

4.80E-05
117

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Hexamethylenediamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 743 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylenediamine
5553
124094
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










150




750
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1977
Critical Effect










2-generation study; reduced litter size, reduced
maternal and pup weights




Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Short el a , 1991 , NOAEL
Lowest Observed Adverse Effect Level
Supplemental Data


rodent, rat; TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth,
MN 55802) V.1- 1959- Volume(issue)/page/year 42,417,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,050

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Hexamethylenediamine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 744 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

286


3.20E-09
2,460,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Hexamethylenetetramine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 745 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hexamethylenetetramine
4151
100970
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












1,234


569
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1970
Critical Effect












Yellow discoloration of fur


Behavioral - excitement, Behavioral - muscle contraction
or spasticity
Prevalence Magnitude ,,, „
7 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, Porta, 1965, LOAEL


Rodent, mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year
35(3), 115,1970
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,879

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hexamethylenetetramine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 746 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Adhesives/coatings; medications; catalyst (HSDB)
Value

553


1.60E-09
667,000
98
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
HMX
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 747 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
HMX
13804
2691410
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.05
0.05
0.05
0.05






0.994




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988
1988

1997






1975




Critical Effect

Hepatic lesions

Hepatic lesions
Hepatic






Brain and Coverings - other degeneratve changes,
Behavioral - alteration of classical conditioning




Prevalence Magnitude ,,, „
3 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S. DOD, 1985a; Basis NOAEL 50 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; U.S. DOD, 1985a; Basis NOAEL/LOAEL 50 mg/kg-d, rat, UF=1000
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 22-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/vear 40(1 1 ), 1 7, 1 975
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1






1989













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


2
350

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   HMX
   CCL 3 Contaminant Information Sheet
                                                                                        EPA-OGWDW
    August 2009
Page 748 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>500K-1 M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Explosive (HSDB)
Value
38 days
1,853
0.82

8.66E-10
2,556

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Hydrochloric acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 749 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrochloric acid
19106
7647010
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













900


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date













1996


Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude
10 10
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1835, rabbit


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N

W/L
W/L






Teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Hydrochloric acid
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 750 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in food processing (HSDB)
Value

14.3
0.54

0.0245
42,400

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Hydrocinnamic acid, 3,5-di-tert
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 751 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-,
methyl ester
17833
6386385
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











600




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Behavioral - food intake (animal), Liver - other
changes, Blood -changes in leukocyte (WBC) count




Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield,
VA 221 61) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0539881; 90-day rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,400

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hydrocinnamic acid, 3,5-di-tert
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 752 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate; in etching (HSDB - uses for 1,2-, 1,3- and 1,4-diethylbenzene)
Value
60 days





6
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
Hydrogen sulfide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 753 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydrogen sulfide
19345
7783064
Attribute Scores
Potency Severity
6 3
Prevalence Magnitude
10
ncomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.003

0.03












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect

Gastrointestinal disturbance. RfD withdrawn in IRIS
2003. Questionable study.















3-model Categorical Prediction

HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Watterau etal., 1964, NOAEL, pig, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve

Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



21

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hydrogen sulfide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 754 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; disinfectant (HSDB)
Value

14.3
-1.38

0.00869
3,740

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Hydroquinone
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 755 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydroquinone
5502
123319
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.04







35.7




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect



Hematological effects







Kidney, Ureter, Bladder - changes in tubules (including
acute renal failure, acute tubular necrosis), Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - multiple enzyme effects




Prevalence Magnitude
8 8 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Carlson and Brewer, NOAEL, human, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 23,397,1994
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.056



3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


280
0.625
Y/N
Y/N

W/L
W/L










RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hydroquinone
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 756 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

11,265
574,933
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

4
14
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Photographic chemical; antioxidant; chemical intermediate; medication (HSDB)
Value

434
0.59

4.72E-11
72,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Hydroxyethyl methacrylate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 757 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Hydroxyethyl methacrylate
9951
868779
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









30

2.5



3,275
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987



1989
Critical Effect









Decreased relative organ weight

Liver - other changes, Blood - changes in spleen



Behavioral - coma
Prevalence Magnitude
6 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 35-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 52(11), 81, 1987
Supplemental Data


Rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 54(9), 75,1989
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Hydroxyethyl methacrylate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 758 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10M-50M
>10M-50M
Polymer intermec
Value

43
0.47

4.60E-09
1,000,000
39
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Iron pentacarbonyl
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 759 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
ron pentacarbonyl
22932
13463406
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













12


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1996


Critical Effect













Nanomaterial - no information provided


Prevalence Magnitude , „ ,
2 6 Li L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1946, rabbit


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Iron pentacarbonyl
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 760 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
43,51 r
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Gasoline additive; chemical intermediate (HSDB)
Value


3


50-100

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Isobutanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 761 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutanol
2836
78831
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.3

3







1,022



74.1
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1984
Critical Effect

Hypoactivity & ataxia









Behavioral - somnolence (general depressed activity),
Nutritional and Gross Metabolic - changes in potassium,
Related to Chronic Data - death



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude „, „ , „
8 7 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S.EPA, 1986, NOEL 316 mgrtsg-d, rat, UF=1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS0531 063
Supplemental Data


VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. etal., Chimia,
1 994. Volume(issue)/page/year -, 1 02, 1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,100

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Isobutanol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 762 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; solvent; flavoring (HSDB)
Value

2.05
0.76

9.79E-06
85,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Isobutene
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 763 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutene
5093
115117
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
10 8
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L










Some evidence of carcinogenicity in male rats (NTP)

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isobutene
   CCL 3 Contaminant Information Sheet


OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 764 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units

Cancer:



Notes





Chemical intermed ate; octane enhancer; in polymers (HSDB)
Value
15
450
2.34

0.218
263
88
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Isobutyl acetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 765 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sobutyl acetate
4829
110190
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















4,763
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mgflsg
Date















1972
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
75 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rodent-rabbit; IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.1 8-42, 1949-73. For
publisher information, see IOHSA5. Volume(issue)/page/year 41,31, 1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isobutyl acetate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 766 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; so vent (HSDB)
Value

200
1.78

0.00045
6,300
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Isobutyronitrile
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 767 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isobutyronitrile
2835
78820
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













25


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1996


Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude , „ ,
55 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY:
Van Nostrand Reinhold, 1996., p. 1960, mouse


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isobutyronitrile
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 768 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; gasoline additive (HSDB)
Value

42
0.46

5.39E-05

43
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Isooctyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 769 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sooctyl acrylate
30980
29590429
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1991
Critical Effect















Behavioral -somnoence (general depressed activity),
Behavioral - ataxia, Gastrointestina - hypermotility,
diarrhea
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave.,
NW, Washington, DC20005) V.1- 1975/76- Volume(issue)/page/year34,297,1991, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isooctyl acrylate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 770 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemical (EPA/SRS)
Value
1 5 days





16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Isophthalic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 771 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isophthalic acid
5410
121915
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










250




10,400
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1986
Critical Effect










Kidney effects - crystalluria, mild hydronephrosis,
pelvic calcification




Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, 0 , „
8 7 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Sid assessment
Lowest Observed Adverse Effect Level
Supplemental Data


rodent-rat; 85JCAE "Prehled Prumyslove Toxikoogie; Organicke Latky," Marhold, J., Prague,
Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year -,317,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,750

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isophthalic acid
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 772 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical and polymer intermediate (HSDB)
Value
1 5 days
72
1.66

2.90E-13
130
27
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Isoprene
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 773 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isoprene
2833
78795
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











2.49




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgftg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1959




Critical Effect











Behavioral - alteration of classical conditioning




Prevalence Magnitude , „ ,
88 L' L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (WOMezhdunarodnayaKniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year24(6),8,1959
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


5.81

Y/N
Y/N

M8/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isoprene
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 774 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n synthesis of rubber and natural products (HSDB)
Value
1 5 days
490
2.42

0.077
642
89
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Isopropanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 775 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isopropanol
2509
67630
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
BMDL
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








407


18

4.5

3,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994

1993-1994


Critical Effect








Decrease in male mating index.(another study- Gentry,
et al. give 500mg/kg NOAEL and also add decreased
fetal body weight).


Endocrine - effect on menstrual cycle; Reproductive -
Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)



Behavioral - altered sleep time (including change in
righting reflex), Behavioral - somnolence (general
depressed activity); AND Behavioral - general anesthetic
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data (Benchmark Dose), BMDL10, Shipp et al. 1996
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 122-day oral study in rat; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia
Supplemental Data
mouse; Clayton, G. D., F. E. Clayton (eds.) Patty's Industrial Hygiene and Toxicology. Volumes 2A, 2B,
2C, 2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994, p. 2630

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
11 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 43(1), 8,1 978; AND VCVGK "Vrednie
chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous
substances. Ga ogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.
Volume(issue)/page/vear -, 97,1 984
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

2,849

Y/N
Y/N

W/L
W/L






teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Isopropanol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 776 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; food additive; solvent (HSDB)
Value

1.06
0.05

8.10E-06
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Isopropyl formate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 777 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Isopropyl formate
8937
625558
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1969
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude ,
5 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


28ZEAL "Pesticide Index," Frear, E.H., ed.( State College, PA, College Science Pub., 1969
Volume(issue)/page/year 4,256,1969, rodent-guinea pig
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isopropyl formate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 778 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fumigant; chemica intermediate (HSDB)
Value
1 5 days
18


0.000775
20,700
49
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Isopropylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 779 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
sopropylamine
2645
75310
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















111
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral - somno ence (general depressed activity),
Lungs, Thorax, or Respiration -dyspnea,
Gastrointestinal - other changes
Prevalence Magnitude , „ ,
88 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear OTS054201 1 , rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Isopropylamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 780 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate (HSDB)
Value

30
0.26


1,000,000
49
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
Kodaflex txib
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 781 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Kodaflex txib
18352
6846500
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









30






Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
7 5

Critical Effect









Increased liver weight; Increase in grade of change of
renal tubular epithe ium and hyaline droplet
degeneration.






3-model Categorical Prediction
NL"7 - L"7
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Kodaflex txib
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 782 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Plasticizer in food packaging (ChemlDPIus)
Value
38 days





12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Lactofen
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 783 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lactofen
65964
77501634
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.008
0.002

0.002












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect
Kidney lesions and weight changes to the thyroid and
adrenal glands
ncr. abs./rel. liver weight; hepatocytomegaly-M

ncreased absolute and relative weight; hepatocytomegaly
in males












Prevalence Magnitude , „ ,
10 6 L' L
HRL Ratio(s)
NC HRL/SWC EEC: 4,667
Notes
Reference Dose
Reference Dose, PPG Industries, 1985a, LEL 1.5 mg/kg-d, mouse, UF=1000
Reference Dose
Reference Dose, PPG Industries, 1985a, LEL, mouse, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


56

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Lactofen
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 784 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP


# Sam pies
Amount
Released
389,388
0
0
n
PWSs/Sites/Sa
mples
115
OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects
Units
Ibsfyr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States
26
0
0
%
PWSs/Sites/Sam
pies with
detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects



Maximum
value of
Detects
Year
1997
2002
2002
Maximum
value of
Detects

Surface water chronic: 0.012 ug/L

Non-cancer: 4,667
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Notes
Pesticide Data Program (USDA) 2002
Ground water chronic:

Cancer:







Herbicide (HSDB)
Value

25,400
4.81

5.73E-10
0.1
3
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Lactonitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 785 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lactonitrile
2849
78977
Attribute Scores
Potency Severity
5 4
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









6




31

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Liver cell enlargement or alteration, Blood- signif
decreases in GOT and signif increases in total protein,
albumin, and Ca. Swelling of Liver.







3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose

Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data

male'

Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



42

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Lactonitrile
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 786 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>10M-50M
Units
Ibs/yr
Ibs/yr
Year

1994





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate (HSDB)
Value
9 min
1
-0.94

9.80E-06
1,000,000
45
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
lambda-Cyhalothrin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 787 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
lambda-Cyhalothrin
67650
91465086
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.005













56
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1991
Critical Effect

Decreased maternal weight gain during pregnancy;
decreased neonatal weight gain during weaning













Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „ ,
10 6 L"L
HRL Ratio(s)
NC HRL/SWC EEC: 357
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968- Volume(issue)/page/year 9,203,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   lambda-Cyhalothrin
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 788 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP



# Sam pies

Amount
Released
321,284


n
PWSs/Sites/Sa
mples
0
OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects

Number of
States
43


/o
PWSs/Sites/Sam
pies with
detects
0



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected



Maximum
value of
Detects

Year
1997


Maximum
value of
Detects
Not Detected
Surface water chronic: 0.098 ug/L

Non-cancer: 357
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
99% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Pesticide Pilot Monitoring Program (USGS/EPA) 9002(GC/MS)
Ground water chronic: 0.01 2 ug/L

Cancer:







nsecticide (HSDB - data for cyhalothrin, CASRN 68085-85-8)
Value


7

1.35E-05
8,530
1
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Lead acetate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 789 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lead acetate
11430
1335326
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude ,
5 10 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.038

B

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1


















From OEHHA

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.921
Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Lead acetate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 790 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1986
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Analytical reagent (HSDB)
Value


-4


250,000

Units
ength of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Linuron
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 791 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Linuron
6584
330552
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.008
0.002

0.002







4.93




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986









1975




Critical Effect
Decreased RBC count, hematocrit& hemoglobin levels

Abnormal blood pigment
Abnormal blood pigment







Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other Enzymes




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA 90% : 21 5
Notes
Reference Dose; du Pont, 1962
Reference Dose
Reference Dose; du Pont, 1962; Basis LEL 0.625 mg/kg-d, dog, UF=300
Reference Dose; du Pont, 1962; Basis LEL, dog, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 31-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 40(7), 46,1 975
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




C

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1






1989













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

56

Y/N
Y/N

W/L
W/L






Developmental




CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Linuron
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 792 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
298


0


0


Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP

CAL DHS
HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,142


# Sam pies
Amount
Released
516,133
0
11
n
PWSs/Sites/Sa
mples
154
339


# Sites
142
105


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


1
0
#with Detects
0
1.47


% Samples with
detects
Number of
States
35
0
2
%
PWSs/Sites/Sam
pies with
detects


0.3
0
% PWSs/Sites
with detects
0
0.0005


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects



Not Detected
Minimum value of
Detects
Not Detected
Non-cancer: 215
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.4


Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Not Detected
Maximum
value of
Detects
Not Detected
0.03


Median value of
Detects
0.26


90% of
Detects
0.74


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



Not Detected
Median value of
Detects
Not Detected
99% of
Detects



Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA)2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001 (GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) 9060 (HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Herbicide (HSDB)
Value
60 days
350
3.2

6.26E-09
75
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Lithium carbonate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 793 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lithium carbonate
7842
554132
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











10



404
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999



1998
Critical Effect











Brain and Coverings - recordings from specific areas
of CNS, Liver - liver function tests impaired, Blood -
pigmented or nucleated red blood cells



Peripheral Nerve and Sensation - flaccid paralysis with
appropriate anesthes a, Behavioral - tetany, Cardiac -
arrhythmias (including changes in conduction)
Prevalence Magnitude
87 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, STGNBT "Spravochnik po Toksikologii i Gigienicheskim
Normativam (PDK) PotentsiaPno Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B.
Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
Supplemental Data


VCVN1 "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp"
(Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
Volume(issue)/page/year -, 25,1 998
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

23.3

Y/N
Y/N

M8/L
W/L






Developmental




CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Lithium carbonate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 794 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

5
21 1 ,661
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
14
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Coatings; chemica intermediate; medication (HSDB)
Value





13,100

Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Lithium chloride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 795 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Lithium chloride
18915
7447418
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.009



526
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999



1998
Critical Effect











Cardiac - pulse rate increase, without fall in BP, Liver -
iverfunction tests impaired, Blood - changes in
erythrocyte (RBC) count



Behavioral - tetany, Lungs, Thorax, or Respiration -
respiratory depression, Gastrointestinal - hypermotility,
diarrhea
Prevalence Magnitude
1
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; STGNBT "Spravochnik po Toksikologii i Gigienicheskim
Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B.
Gorshkova, eds. 46, ZhivopisnayaSt., 123182, Moscow, Russia, IzdAT 1999
Supplemental Data


VCVN1 "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp"
(Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
Volume(issue)/page/year -, 26,1 998
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.021


Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Lithium chloride
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 796 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L





ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; salt baths; dessicant; in welding (HSDB)
Value





832,000

Units
length of time
Ukg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Malathion
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 797 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Malathion
5402
121755
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.07
0.02
0.02
0.02
0.02
0.3





0.34




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987









2001




Critical Effect
RBC ChE inhibition
Red blood cell cholinesterase inhibition

RDB ChE depression
cholinesterase inhibit on






Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase




Prevalence Magnitude
9 3 NL
HRL Ratio(s)
NC HRL/NAWQA 90%: 5,698
Notes
Reference Dose, Moeller and Rider, 1962
Reference Dose, Moeller and Rider, 1962, basis NOEL 0.23 mg/kg-d, human, UF=10
Reference Dose
Reference Dose, Moeller and Rider, 1 962, basis NOEL/LEL, human, UF=1 0
Minimal Risk Level, Daly, 1996, basis NOAEL 2 mg/kg-d, rat, UF=100
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 56-day oral study in human; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 1 ,59,2001
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW MAC

Y
0.8
490

0.19
Y/N
Y/N
mg/L
W/L
W/L
mg/L







teratogen





UMD
Drinking Water Equivalent Level



1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Malathion
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 798 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total

TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,117

# Sam pies

Amount
Released
5,809,943
10,288
24,199
n
PWSs/Sites/Sa
mples
283
669

271

344

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0
0

4.83

% Samples with
detects

Number of
States
42
2
8
/O
PWSs/Sites/Sam
pies with
detects


0
0

0.0015

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Not Detected
Not Detected

Non-cancer: 5,698
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



9.58

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


Not Detected
Not Detected

0.014

Median value of
Detects

0.086

90% of
Detects

0.39

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
Not Detected
99% of
Detects


Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

Cancer:







Insecticide; veter nary medicine (HSDB)
Value
11 days
30.5
2.36

4.89E-09
143

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Maleic anhydride
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 799 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maleic anhydride
4681
108316
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.1

0.1











390
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1982
Critical Effect

Renal lesions













Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose U.S. EPA, 1982, NOAEL 10mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, EPA 1983, NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rodent, guinea pig; 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
Volume(issue)/page/year -, 79,1 982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Maleic anhydride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 800 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released

2,185
769,446
# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States

4
31
% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; petroleum additive (HSDB)
Value
0.37 minutes
1
1.62

3.94E-06
4,912
35
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Maleic hydrazide
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 801 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maleic hydrazide
5504
123331
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.25
0.5
0.5
0.5

0.3










Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986



1996










Critical Effect
Decreased body weight gain
Kidney

Renal dysfunction












Prevalence Magnitude ,,, „
10 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Uniroyal Chemical, 1981, basis LEL 500 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; Uniroyal Chemical, 1981, basis LEL, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


20
1,750

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Maleic hydrazide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 802 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
2,143,154


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
36


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L





ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (HSDB)
Value

10.4
-0.84

2.64E-11
4,510

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
Malononitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 803 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Malononitrile
4794
109773
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.0001







5.86




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



hepatic effects







Liver - other changes, Kidney, Ureter, Bladder - other
changes




Prevalence Magnitude
2 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, Lonza 1989, NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0526327
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Malononitrile
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 804 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
854,039
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L
s
ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; petroleum additive (HSDB)
Value
15 days
15.3
-0.6

1.27E-08
133,00
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Maneb
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 805 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Maneb
22381
12427382
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.05
0.005

0.005

0.03

0.05








Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
1977
1988



1993










Critical Effect
ncreased thyroid weight &follicular cell hypertrophy,
decreased T4
increased thyroid we ght

increased weight



thyroid








Prevalence Magnitude , „
10 8 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose, Rohm and Haas Co., 1977; Maneb Task Force, 1986,
Reference Dose, Rohm and Haas Co., 1977; Maneb Task Force, 1986, NOEL 5mg/kg-d, primate, UF=100
Reference Dose
Reference Dose; Maneb Task Force, 1986, NOEL/LEL, monkey, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, NOAEL, Ulrich, 1986 and 1987 as cited in JMPR, 1984, rat, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


350

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Maneb
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                          EPA-OGWDW
    August 2009
Page 806 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data



# Sam pies

Amount
Released
3,039,930
0
335

OPP Estimated Environmental Concentration

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr




% Samples with
detects

Number of
States
43
0
1




Minimum value of
Detects

Units
States
States
States




Maximum
value of
Detects

Year
1997
2004
2004

Surface water chronic: 0 ug/L

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic: 0 ug/L

Cancer:







Fungicide (HSDB)
Value

10
0.62

5.65E-07
6.2

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
MCPA
CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 807 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
MCPA
3709
94746
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0044
0.0005

0.0005







3.9



439
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1990



1980
Critical Effect
Hepatotoxicity & nephrotoxicity
kidney, liver









Tumorigenic - carcinogenic by RTECS criteria, Blood -
eukemia



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude .,, „
6 5 NL--L-
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 45.29
Notes
Reference Dose
Reference Dose, Industry Task Force on MCPA, 1986a, Basis NOEL 0.15 mg/kg-d, dog, UF=300
Reference Dose
Reference Dose, Industry Task Force on MCPA, 1986a, Basis NOEL/LEL, dog, UF=300
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 78-week oral study in mouse; TJEMAO Tohoku Journal of
Experimental Medicine. (Maruzen Co. Ltd., Export Dept, P.O. Box 5050, Tokyo Int., 100-31 Tokyo,
Japan) V.1- 1920- Volume(issue)/page/year 160,97,1990
Supplemental Data


RPZHAW Roczniki Panstwowego Zakladu Higieny. (Ars Polona, POB 1001, 00-068 Warsaw 1 , Poland)
V.1- 1950- Volume(issue)/page/year31, 373,1980
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
WHODWQ

Y
0.02
30.8

2
Y/N
Y/N
mg/L
W/L
W/L
W/L







Teratogen





UMD
Drinking Water Equivalent Level



1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   MCPA
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                         EPA-OGWDW
    August 2009
Page 808 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,548

# Sam pies


Amount
Released
5,360,932
0
221
n
PWSs/Sites/Sa
mples
163
285
1
20

44

#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

4

0

0.97

% Samples with
detects


Number of
States
31
0
3
%
PWSs/Sites/Sam
pies with
detects

1.4
0.4
0

0.006

Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

0.012



Non-cancer: 45.29
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



18.6

Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects

0.012



0.17

Median value of
Detects


0.68

90% of
Detects


18.6

99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




99% of
Detects




Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 9060(HPLS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalconta
minants.aspx

Cancer:







Herbicide (HSDB)
Value
15 days
29.4
3.25

1.33E-09
630
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
m-Cresol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 809 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
m-Cresol
4686
108394
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.05

0.05





300

1,500


2,007

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

Decreased body weights & neurotoxicity

Decreased weight and neurotoxicity







Brain and Coverings - changes in brain weight, Liver -
changes in liver weight, Kidney, Ureter, Bladder - changes
in bladder weight




Prevalence Magnitude
8 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1986, 1987, NOAEL, rat, UF=1000
Reference Dose
Reference Dose, U.S. EPA, 1987, NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB92-1 74242
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




C

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

350

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   m-Cresol
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 81 Oof 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

2,547
374,903
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

3
15
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
nsecticide; disinfectant; chemica
Value

434
1.96

8.56E-07
22,700

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ntermediate (HSDB)
Degradation
Code
BF/BFA






Notes
BF = Biodegrades fast/BFA = biodegrades fast with acclimat on (BIODEG)







-------
m-Dichlorobenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 811 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
m-Dichlorobenzene
7698
541731
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.09

0.03






37




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1995




Critical Effect


Hepatic necrosis, porphyria








Endocrine - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cholesterol), Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - dehydrogenases




Prevalence Magnitude ,,, „
4 7 NL'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 70
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level; Int
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; DCTODJ Drug and Chemical Toxicology.
(Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year
18,201,1995
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


3
630

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   m-Dichlorobenzene
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 812 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NGOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

20,429
24,119


51
62


0.25
0.26


0.03
0.1


22.4
15


1.1
0.6


9.1
2.8


22
15

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,353


# Sam pies
Amount
Released

377
1,939
n
PWSs/Sites/Sa
mples
11,938

29


#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1

0.67


% Samples with
detects
Number of
States

3
6
/O
PWSs/Sites/Sam
pies with
detects
0.01

0.001


Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.64

Non-cancer: 70
Amount Range
>500K-1M

Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.1


Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.64

0.017


Median value of
Detects
0.06


90% of
Detects
0.1


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.64

90% of
Detects
0.64

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Fumigant/insecticide; chemical intermediate (HSDB)
Value
38 days
434
3.53

0.00264
125
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Melamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 813 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Melamine
4717
108781
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












178



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1983



Critical Effect












Kidney, Ureter, Bladder chronic inflamation in females;
nephropathy- other changes at both doses - suvival
decreased at high dose (males) - Cancer positive for
males rats and negative forfemale rats and mice



Prevalence Magnitude , „
8 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, NTPTR National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue);page/yearNTP-TR-245,1983



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999





Vol73






Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



415

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Melamine
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 814 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E> Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in resins; eather tanning (HSDB)
Value


-1.37

1.80E-14
3,240
46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
Mepiquat chloride
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 815 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Mepiquat chloride
27927
24307264
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.6
0.03

0.03







75



464
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1992



1991
Critical Effect
Impaired neurological function; vacuolization of the
renal distal tubules; increased hemosiderin functions


Sedation Stonodonic spasms, dec food intake & body wt







Blood - other changes, Nutritional and Gross Metabolic -
weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
9 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; BASF Wyandotte Chemical 1977a; Basis NOEL 25 mg/kg-d, dog, UF=1000
Reference Dose
Reference Dose, BASF WyandotteChemical 1977, NOEL/LEL, dog, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in dog; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,3269,1992
Supplemental Data


FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C241,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



4,200

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Mepiquat chloride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 816 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released
182,576


# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States
16


% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Plant growth regulator (HSDB)
Value
15 days
174
-2.82

4.31 E-1 2
500,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Mercaptoacetic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 817 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Mercaptoacetic acid
2522
68111
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















114
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/Kg
Date
















Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


ZHYGAM Zeitschrift fuer die Qesamte Hygiene und Ihre Qrenzgebiete. (VEB Verlag Volk und
Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955-
Volume(issue)/page/year 20,575,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Mercaptoacetic acid
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 818 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released



# PWSs/Sites
sampled


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects

Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Chemical intermed ate; electroplat
Value

27
0.09

1.90E-08
1,000,000
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Year
1998
2002




Maximum
value of
Detects

Year

2004
2004
Maximum
value of
Detects


Median value of
Detects


90% of
Detects


99% of Detects

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units

Cancer:



Notes





ng; plasticizer (HSDB)
Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Merphos
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 819 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Merphos
6275
150505
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00003

0.00003











170
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988













1962
Critical Effect

Ataxia, delayed neurotoxicity & weight loss

ataxia, delayed neurotoxicity, weight loss











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
NC HRL/CAL DHS 90%: 0.05
Notes
Reference Dose
Reference Dose, Abou-Donia et al., 1980; Basis NOEL 0.1 mgftg-d, hen, UF=3000
Reference Dose
Reference Dose, Abou-Donia et al., 1980 , NOEL/LOAEL, hen, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 27(8), 97,1962
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.21

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Merphos
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 820 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released

9
12
# PWSs/Sites/
Samples
94




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2




% Samples with
detects
Number of
States

1
1
% PWSs/Sites/
Sam pies with
detects
2.13




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
1.5

Non-cancer: 0.05
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
4.3




Median value of
Detects



90% of
Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L


99% of Detects
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
2.9

90% of
Detects
4.02

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Cancelled herbicde (HSDB)
Value
8.7 days
62,400
7.67

2.27E-05
0.0035
6
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (PBT)







-------
Methacrylamide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 821 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylamide
2883
79390
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









12.5





451
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1981
Critical Effect









Decreased body weight





Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, _
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger PI. 3, D-1000 Berlin 33, Fed. Rep.
Ger.) V.32- 1974- Volume(issue)/page/year 47,179,1981
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



87.5

Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methacrylamide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 822 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Polymer intermec
Value
15 days





40
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997


Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (OECD/SIDS)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Methacrylic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 823 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylic acid
2885
79414
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











5



1,060
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1973



1976
Critical Effect











Behavioral - alteration of classical conditioning



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, 0 , „
8 5 NL' L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see H YSAAV.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)Jpage/year
38(8),13,1973
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translaton, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095Moscow, USSR) V.1- 1936- Volume(issue)/page/year 41(4), 6,1976
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



11.7

Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of wa er consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Methacrylic acid
    CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 824 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



^Samples

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Polymer intermediate for resins and coatings (HSDB)
Value

15
0.93

3.90E-07
89,000
40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Methacrylonitrile
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 825 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methacrylonitri e
5635
126987
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0001

0.001





7.5

60


64

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

Transient increase in SGOT & SGPT (liver enzyme)
levels; liver enzyme changes

increased SGOT and SGPT levels







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose, Pozzani et al., 1968, NOAEL 9 mg/m3. Dog, UF=3000
Reference Dose
Reference Dose, Pozzani, 1968, NOAEL/LOAEL.dog, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year PB97-1 76390
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methacrylonitrile
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 826 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603


# Sam pies

Amount
Released

0
89,330
# PWSs/Sites
sampled

0


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0


% Samples with
detects

Number of
States

0
3
% PWSs/Sites
with detects

Not Detected


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-500M
>10M-500M
Polymer intermec
Value
15 days
12.8
0.68

2.47E-04
25,400
49
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected


Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

Not Detected


Median value of
Detects

Not Detected


90% of
Detects

Not Detected


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Methional
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 827 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methional
14647
3268493
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,580
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















2000
Critical Effect















Sense Organs and Special Senses (Eye) - lacrimation,
Lungs, Thorax, or Respiration - dyspnea, Lungs,
Thorax, or Respiration -other changes
Prevalence Magnitude
8 7 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative
Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977-
Volume(issue)/page/year 42,77,2000, LD50 of 1.52 mL/kg converted to mg/kg using a density of
1.041 g/mL (Aldrich Chemical).
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methional
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 828 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Natural flavoring agent; (American Chemical Society/C&E News)
Value
1 5 days





47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Methomyl
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 829 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methomyl
25598
16752775
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.025
0.025
0.025
0.025

0.02





0.1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





2001





1989




Critical Effect
Histopathological effects in the kidney
kidney, spleen

kidney, spleen







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude
2 7 NLi
HRL Ratio(s)
NC HRL/NCOD R2 90%: 106
Notes
Reference Dose
Reference Dose, duPont 1968, NOEL 2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose, duPont 1968, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; JDGRAX Journal of Drug Research.
(National Organ zation for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969-
Volume(issueVoaae/vear 18.145.1989
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




E

mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1






1988













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.9
175

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methomyl
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 830 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


12,659



18



0.1422



Not Detected



3



1.65



1.65



3

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,506

# Sam pies

Amount
Released
1,997,489


# PWSs/Sites
sampled
134
495

# PWSs/Sites/
Samples
4,611
17

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0
#with Detects
1
0.377

% Samples with
detects

Number of
States
42


% PWSs/Sites
with detects


0
% PWSs/Sites/
Sam pies with
detects
0.02
0.0044

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects



Minimum value of
Detects
15
Non-cancer: 106
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.0

Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Maximum
value of
Detects
15
0.22

Median value of
Detects

0.47

90% of
Detects

1.0

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



Median value of
Detects
15
99% of
Detects



90% of
Detects
15
Units for Mag
data



Units for Mag
data
ug/L
Cancer:



Notes
2001
2002
9060 (HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Insecticide (HSDB)
Value
5 days
12.01
0.6

1.97E-11
58,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Methotrexate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 831 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Methotrexate
2369
59052
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.1
0.00435
0.5
180

135
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991


1981

1982
Critical Effect











Liver - hepatitis (hepatocellular necrosis), zonal





Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

0.23

Y/N
Y/N
mg/L
W/L
W/L






Developmental; Teratogen



Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
No data for calcuating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; HPTLD9 Hepatology (Baltimore). (Williams & Wilkins Co.,
Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1981- Volume(issue)/pagefyear
14,906,1991; 6-week study in rat

Maximum Recommended Daily Dose (MRDD)
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Geneva: World
Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work).,
p. V26 275 (1981); Study in rat

Lowest Observed Adverse Effect Level; NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd.,
Tokyo, Japan) Volume(issue)/page/year 6,841,1982; Oral study in rat







CACART
CACART; UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Methotrexate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 832 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREG ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Focazio, etal., 2008

HRL Ratios (No data for calcuating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


26


Amount
Released


# PWS/Sites/
Samples




0


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




0


Number of
States


% PWS/Sites/
Samples with
detects




Not detected


Units
States
States
States
Minimum value of
Detects
Not detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Not detected


Year


Maximum
value of
Detects
Not detected



Not detected




Not detected




Not detected


Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects
Not detected

90% of
Detects
Not detected

Units for Mag
data
ug/L
Notes
Raw drinking water monitoring; Focazio, etal, 2008. Sci. Tot. Env .,
402(2-3): 201 -21 6.

Cancer:







Pharmaceutical
Value
38
1
-1.85

1.50E-31
2,600
46
Units
days
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades Slowly with Acclimation







-------
Methyl acetate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 833 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl acetate
2868
79209
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



1











3,705
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1972
Critical Effect



Increased alkaline phosphatase; liver











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA 1986, NOEL, Increased alkaline phosphatase, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rabbit; IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher
nformation, see IOHSA5. Volume(issue)/page/year 41,31,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7,000

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl acetate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 834 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; food additve; industrial solvent (HSDB)
Value
1 5 days
3.32
0.18

0.000115
243,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Methyl acrylate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 835 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl acrylate
3829
96333
Attribute Scores
Potency Severity
4 1
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.03







149




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1964




Critical Effect



None observed







Behavioral - fluid intake, Kidney, Ureter, Bladder - changes
in bladder weight, Nutritional and Gross Metabolic - weight
oss or decreased weight gain





3-model Categorical Prediction
NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1987, NOEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year6,29,1964
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1






1990
1999











Vol. 39, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl acrylate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 836 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603

# Sam pies

Amount
Released

728
206,487
# PWSs/Sites
sampled

0

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0

% Samples with
detects

Number of
States

5
20
% PWSs/Sites
with detects

Not Detected

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Polymer intermec
Value

6.42
0.8

0.000197
49,400

Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

Not Detected

Median value of
Detects

Not Detected

90% of
Detects

Not Detected

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate; in adhesive formulations (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Methyl carbamate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 837 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl carbamate
8351
598550
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











71.4




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood - leukemia, Tumorigenic - active as anti-cancer
agent




Prevalence Magnitude
5 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, NTIS National Technical Information Service. (Springfield,
VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)Apage/yearPB88-168570/AS
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







1987











Vol. 12, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


167

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl carbamate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 838 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
1 5 days
10
-0.66

4.00E-08
691,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Methyl mercaptan
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 839 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl mercaptan
2609
74931
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













61


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













2001


Critical Effect
















Prevalence Magnitude
10 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley &
Sons. New York, N.Y. (2001)., p. 688


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl mercaptan
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 840 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; natural gas additive (HSDB); gas
Value

14.3
0.78

3.13E-03
15,400
75
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Methyl methacrylate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 841 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyl methacrylate
2958
80626
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

1.4

1.4



0.05



0.357




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







1992



1976




Critical Effect

None, Marginally significant increase in kidney to body
weight ratio. Decreased Potency Score by one integer





kidney



Brain and Coverings - other degeneratve changes, Liver -
other changes, Biochemical - Enzyme nhibition, induction,
or change in blood or tissue levels - transaminases




Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Borzelleca et al., 1864, NOEL 136 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake, Borzelleca et al., 1964, NOEL, rat, UF=100
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 39-week oral study in rabbit; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year41(4),6,1976
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




E
3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1997
1994











Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

9,800

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyl methacrylate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 842 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,603
# Sam pies


Amount
Released

2,408
3,657,567
# PWSs/Sites
sampled

0
#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0
% Samples with
detects


Number of
States

8
39
% PWSs/Sites
with detects

Not Detected
Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value

10.14
1.38

0.000338
15,000

Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected
Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects

Not Detected
Median value of
Detects


Not Detected
90% of
Detects


Not Detected
99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Methylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 843 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylamine
2607
74895
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















100
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1390
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
75 L' L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


INHTE5 Inhalation Toxicology. (Published by Taylor & Francis Health, 1 1 New Fetter Lane, London
EC4P4EEJV.1- 1989- Volume(issue)/page/year 2,29,1990
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methylamine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 844 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ntermediate for accelerators, dyes, Pharmaceuticals, insecticides, tanning; fuel additive (HSDB)
Value

389
0.57

1.11E-05
1,250,000
48
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Methylcyclopentadienyl manganes
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 845 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylcyclopentadienyl manganese tricarbonyl
22045
12108133
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











20T



8
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1992



1976
Critical Effect











Kidney, Ureter, Bladder - other changes in urine
composition, Blood - changes in serum composition
e.g. TP, bilirubin, cholesterol), Nutritional and Gross
Metabolic - weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AECTCV Archives of Environmental Contamination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issue)/page/year 23,473,1 992
Supplemental Data


TMMT "The Toxicology of Methylcyclopentadienyl Manganese Tricarbonyl," Witherup, S., et al.,
Cincinnati, OH, Univ. of Cincinnati, 1976 Volume(ssue)/page/year -,-,1976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



482

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methylcyclopentadienyl manganes
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 846 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997


Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Fuel additive (HSDB); gas
Value


3.7


29

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Methyleugenol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 847 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyleugenol
3608
93152
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










10
0.0714




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










2001
2001




Critical Effect










Increased liver weights, decreased body weight gain
Endocrine - changes in spleen weight, Blood - changes in
platelet count, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases




Prevalence Magnitude ,,,
1 3 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental NOEL, Abdo, et al. 2001. Food and Chemical Toxicology 39 (2001) 303-316.
Lowest Observed Adverse Effect Level; 1 4-week oral study in rat; FCTOD7 Food and Chemical
Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year39,303,2001
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70

Y/N
Y/N

M8/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Methyleugenol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 848 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released



# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10K-500K
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997


Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; flavorant; insect attractant (HSDB)
Value
34 hours
140
3.03

5.60E-06
500
19
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Methylglutaronitrile
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 849 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methylglutaronitrile
16055
4553622
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















10
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1969
Critical Effect















Behavioral - convulsions or effect on seizure
threshold, Behavioral - excitement, Lungs, Thorax, or
Respiration - cyanosis.
Prevalence Magnitude , „ ,
6 7 L"L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed. Rep. Ger.) V.I -25,
1951-75. Volume(issue)/page/year 19,225,1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Methylglutaronitrile
    CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 850 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997


Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; solvent (HSDB)
Value
15 days
10.7
-0.644



39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Methyltrichlorosilane
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 851 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Methyltrichlorosilane
2682
75796
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













800


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1981-1982


Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude , „ ,
8 5 L"L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G. D. and F. E. Clayton (eds.). Pattys Industrial Hygiene and Toxicology: Volume 2A, 2B,
2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2398


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Methyltrichlorosilane
    CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 852 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
50M-10M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997


Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value
rapid





40
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Metiram
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 853 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Metiram
20233
9006422
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.004




0.03





73.9



620
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1993





2000



1980
Critical Effect
Decrease forelimb grip strength










Endocrine - changes in thyroid weight, Blood - changes in
erythrocyte (RBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
9 7 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Group ADI with MANCOZED, MANEB AND ZINEB
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; TOSCF2 Toxicological Sciences
(Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41 , Jan. 1 998-
Volume(issue)/page/year 54,481 ,2000
Supplemental Data


VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1924- Volume(issue)/page/year 56(6),59,1980
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

28

Y/N
Y/N

W/L
W/L






Developmental



CACART
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Metiram
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 854 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies

Amount
Released
1,385,330



OPP Estimated Environmental Concentration

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
24





Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997



Surface water chronic: 0 ug/L

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic: 0 ug/L

Cancer:







Fungicide (HSDB)
Value

100,000
0.3

9.30E-18


Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Metribuzin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 855 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Metribuzin
27143
21087649
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.013
0.025
0.025
0.025







0.617




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1990




Critical Effect
ncreased absolute & relative thyroid weight, increased
T4, decreased T3 in blood.
Liver; kidney; body weight; mortality









Brain and Coverings - other degeneratve changes




Prevalence Magnitude
1 7
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 45.5
Notes
Reference Dose, Mobay Chemical, 1974a
Reference Dose, Mobay Chemical, 1974a, NOEL 2.5 mg/kg-d, dog, UF=100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1 5-week oral study in rat; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volumefissuel/Daae/vear 30.209.1990
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
CADW MAC
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.9
80
91

Y/N
Y/N

W/L
W/L
W/L














Drinking Water Equivalent Level
Canadian Drink ng Water Maximum Acceptable Concentration


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Metribuzin
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 856 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


13,568



9



0.0663



0.1



2



1.1



2



2

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
Supplemental Water Data
PPMP
PPMP
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,165
# Sam pies
Amount
Released
3,320,231
24
847
# PWSs/Sites/
Samples
288
582
# PWSs/Sites/
Samples


# PWSs/Sites/
Samples
7,281
459
#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
1

#with Detects
47
0
#with Detects
1
6.41
% Samples with
detects
Number of
States
48
2
3
% PWSs/Sites/
Sam pies with
detects
0.3

% PWSs/Sites/
Samples with
detects
14.6
0
% PWSs/Sites/
Samples with
detects
0.01
0.002
Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.042

Minimum value of
Detects


Minimum value of
Detects
4
Non-cancer: 45.5
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



6.61
Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
0.042

Maximum
value of
Detects


Maximum
value of
Detects
4
0.022
Median value of
Detects
0.24
90% of
Detects
2.26
99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.042

Median value of
Detects


Median value of
Detects
4
99% of
Detects
0.042

95% of
Detects
0.004

90% of
Detects
4
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Units for Mag
data
ug/L
Cancer:



Notes
2001
2002
Notes
2001 raw water (GC/MS)
2001 finished water (GC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Herbicide (HSDB)
Value

1,196
1.7

1.17E-10
1,050

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Molybdenum trioxide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 857 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Molybdenum trioxide
11108
1313275
Attribute Scores
Potency Severity
5 5
Prevalence Magnitude
9 8
Scores based on parent Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.005














Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

ncreased uric acid levels
(for molybdenum)














3-model Categorical Prediction
L?
HRL Ratio(s)
NCHRL/NIRS90%: 1.10
Notes
Reference Dose
Reference Dose, U.S. EPA, 2003
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Molybdenum trioxide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 858 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



77



7.79



6.1



180



10



30



110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released

36,579
2,102,324
# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States

18
36
% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer: 1.10
Amount Range
10M-50M

Catalyst; chemica
Value





1,066

Units
Ibs/yr
Ibs/yr
Year
1986
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes




Scores based on parent (molybdenum)


National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





intermediate (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
N.N'-Diethylthiourea
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 859 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N.N'-Diethylthiourea
4461
105555
Attribute Scores
Potency Severity
6 9
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















316
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1973
Critical Effect















Details of toxic effects not reported other than lethal
dose value

3-model Categorical Prediction
L?
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(NCILB Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer
Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year NCI-E-C-72-3252,1 973)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1



















Vol 79; 2001
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

M8/L
W/L










IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   N.N'-Diethylthiourea
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 860 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rubber accelerator; corrosion inh bitor (HSDB)
Value
1 5 days
49
0.57

6.85E-08
4,555
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
N, N-Dimethylacetamide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 861 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N, N-Dimethylacetamide
5644
127195
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.583

65
2

4,390


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1980




Critical Effect










decreased fetal body weights in the absence of
maternal toxicity
Liver - other changes, Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - other
esterases, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - transaminases




Prevalence Magnitude
6 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data, Johannsen etal 1987
Lowest Observed Adverse Effect Level; 26 week rat study
Supplemental Data
Kennedy, GL Jr, Sherman H; Drug ChemToxicol9 (2): 147-70(1986); Prager, J.C. Environmental
Contaminant Reference Databook, Volume 1. New York, NY: Van Nostrand Reinhold; rat


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

455

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    N, N-Dimethylacetamide
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 862 of 1124
OCCURRENCE DATA

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent (HSDB)
Value

9
-0.77

1.31E-08
1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (HSDB)







-------
N,N-Dimethylethanolamine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 863 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N,N-Dimethylethanolamine
4658
108010
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










450

15



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect










increased liver and kidney weights





Prevalence Magnitude
7 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP summary of tox literature. NOAEL 450 mg/kg/day (Smyth etal, 1951
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3,150

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    N,N-Dimethylethanolamine
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 864 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released



# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Medication; chem
Value


-0.94

3.73E-07
1,000,000
40
Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
u
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





cal intermediate; stabilizer (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Naled
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 865 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Naled
6448
300765
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.002
0.002









21.4



92
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1969



1990
Critical Effect
Brain ChE inhibition
Brain cholinesterase nhibition

ChE inhibintion







Nutritional and Gross Metabolic - body temperature
decrease, Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - true cholinesterase,
Related to Chronic Data - death



Behavioral - tremor, Gastrointestinal - changes in structure
or function of salivary glands, Gastrointestinal -
hypermotility, diarrhea
Prevalence Magnitude , „
96 L
HRL Ratio(s)
NC HRL/SWC EEC: 25
Notes
Reference Dose
Reference Dose, Chevron Chem cal Co., 1984a, NOEL 0.2 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose, Chevron Chem cal Co., 1984a, NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; RPZHAW Roczniki Panstwowego
Zakladu Higieny. (Ars Polona, POB1001, 00-068 Warsaw 1 , Poland) V.1- 1950-
Volume(issue)/page/year20,463,1969
Supplemental Data


Rat; ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann
Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year 1,90,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Naled
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 866 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS



# Sam pies

Amount
Released
605,456
0
0
# PWSs/Sites/
Samples
14
OPP Estimated Environmental Concentration
HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects

Number of
States
16
0
0
% PWSs/Sites/
Samples with
detects
0



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected



Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected
Surface water chronic: 0.56 ug/L
Non-cancer: 25
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.005 ug/L
Cancer:







nsecticide; veter nary medicine (HSDB)
Value

96.03
1.38

6.51 E-05
1.5
37
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Naphthalene
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 867 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Naphthalene
3465
91203
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02
0.02
0.02
0.6






60




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1970




Critical Effect

Decreased terminal body weight

Decreased mean terminal body weight in males
Neurol.






Endocrine - changes in adrenal weight




Prevalence Magnitude
7 6 NLi
HRL Ratio(s)
NC HRL/NCOD R1 90%: 17.5
Notes
Reference Dose
Reference Dose, BCL 1980, NOAEL 100 mgflsg-d; adjusted NOAEL 71 mg/kg-d, rat, UF=3000
Reference Dose
Reference Dose, BCL 1980, NOAEL/LOAEL, rat, UF=3000
Minimal Risk Level-lnt.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 28-day oral study in rat; BIOFX BIOFAX Industrial Bio-Test
Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year 16-
4/1970
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




C
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.7
140

Y/N
Y/N

W/L
W/L






Teratogen



CACART; IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Naphthalene
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 868 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

13,452
22,926


159
176


1.18
0.768


0.03
0.07


906
90


1
0.736


8
3.1


900
73

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,310
85
# Sam pies

Amount
Released

17,809
3,456,696
# PWSs/Sites/
Samples
sampled
10,913

83
14
#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
20

1.926
16.5
% Samples with
detects
6.31
1.35
Number of
States

41
53
% PWSs/Sites/
Samples with
detects
0.18

0.005
Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.008

Non-cancer: 17.5
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



70
Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
7

0.072
0.020
Median value of
Detects
0.135
0.9
0.7
90% of
Detects

43
99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.88

90% of
Detects
4.07

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; chemical intermediate; moth repellant (HSDB)
Value
38 days
1,837
3.3

0.00044
31
13
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
n-Butyl acetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 869 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
n-Butyl acetate
5537
123864
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













14,000


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1993-1994


Critical Effect













Paper by Davis et al, suggests that n-butanol data are
appropriate for the effects of n-butylacetate since n-
butylacetate are readily hydrolyzed to n-butanol. In an
inhalation study, there was some minor evidence of
gastric irritation from the n-butyl acetate.


Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Clayton, G.D., F.E. Clayton (eds.) Pattys Industrial Hygiene and Toxicology. Volumes 2A, 2B, ZC,
2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994., p. 2980


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   n-Butyl acetate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 870 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997


Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; flavoring additive; industrial solvent (HSDB)
Value

200
1.78

0.00028
14,000
33
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
n-Butyl methacrylate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 871 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
n-Butyl methacrylate
3916
97881
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









30

3.57



12,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1976



1976
Critical Effect









Spleen toxicity, decreased absolute and relative
weights of the spleen.

Brain and Coverings - recordings from specific areas of
CNS, Behavioral - alteration of classical conditioning, Liver
- other changes; Blood - pigmented or nucleated red blood
cells, Blood - changes in serum composition (e.g. TP,
bilirubin, cholesterol), Biochemical - Enzyme inhibition,
induction, or change in blood or tissue evels - catalases



Details of toxic effects not reported other than lethal dose
value

3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 39-week oral study in rat and rabbit; GISAAA Gigiena i
Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow,
USSR) V.1- 1936- Volume(issue)/page/year 41(4), 6,1976
Supplemental Data


Mouse; GISAAA Gigiena i Sanitariya.
Kniga, 113095 Moscow, USSR) V.1-
-or English translation, see HYSAAV. (V/O Mezhdunarodnaya
1 936- Vo ume(issue)/page/year 41 (4) ,6, 1 976
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   n-Butyl methacrylate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 872 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-SOM
Polymer intermec
Value
8.7 days
880
2.88

0.00079

24
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997


Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Neopentyl glycol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 873 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Neopentyl glyco
5606
126307
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









100






Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









ncreased liver weight; increased kidney weight






Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Neopentyl glycol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 874 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997


Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (Merck Index, 1983)
Value


0.16



44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Nickel
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 875 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nickel
18829
7440020
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02

0.02












Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1995














Critical Effect

Decreased organ (kidney, liver & spleen) & body
weights














Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




1
mg/L
(mg/kg-d)-1
(mg/kg-d)-1






1990





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y
0.7
140

Y/N
Y/N
mg/L
W/L
W/L


1995



Teratogen



Prevalence Magnitude , „
98 L
HRL Ratio(s)
NCHRL/NIRS90%: 0.74
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; IRIS
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data






OEHHA, Class A

Vol. 49; 1 997; Cancer classifications were used for screening, but no related quantitative cancer risk data
were identified for potency scoring.

IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Nickel
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 876 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



47



4.75



5



150



7.6



190



110
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
3,298



Amount
Released

29,802
6,119,051
# PWSs/Sites
sampled

2,171



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

65.8



Number of
States

37
49
% PWSs/Sites
with detects

0.03



Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.74
Amount Range
10K-500K

Units
Ibs/yr
Ibs/yr
Year
1998
2002



666



Year

2004
2004
Maximum
value of
Detects

2



6



29.7



Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Use data are for n ckel sulfate: Steel making, catalysts, storage batteries, specialty chemica s, and specialty ceramics (HSDB); naturally-occurring
Value





389,900

Units
length of time
cm3/g
unitless
cm3/g
unitless
mg/L

Degradation
Code
BST






Notes
assume persistent; all use and env. fate data are for nickel sulfate; BST = biodegrades sometimes/recalcitrant







-------
Nickel compounds
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 877 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nickel compounds
44

Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
10 10
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02














Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

Decreased body and organ weights















3-model Categorical Prediction
L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, Rat chronic oral study, Ambrose et al, 1 976
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





1
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1990











Vol. 49
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

140

Y/N
Y/N

W/L
W/L






Teratogen



IARC
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Nickel compounds
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 878 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

170,937
34,676,669
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

45
52
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L





ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Electroplating; steel additives (HSDB)
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Niobium
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 879 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Niobium
18830
7440031
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












316



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












hyperplasia and hyperkeratosis of the stomach



Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, OPPTS summary LOAEL 316 mg/kg/day ammonium niobium dioxylate oxide
pentahydrate.



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

8.03E-13




mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


22.1

Y/N
Y/N

W/L
W/L










RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Niobium
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 880 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1986
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L





ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n alloys; in nuclear reactions (Merck Index, 1983)
Value



350



Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Nitrilotriacetic acid
CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
    August 2009
Page 881 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitrilotriacetic acid
5991
139139
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








0.01


1.05




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1979




Critical Effect








Increased incidence of nephritis & nephrosis,
hyperglycaemia


Kidney, Ureter, Bladder - other changes in urine
composition, Kidney, Ureter, Bladder - changes in bladder
weight, Nutritional and Gross Metabolic - changes in
calcium





3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data, Health Canada ADI
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 4-week oral study in rat; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year 17,137,1979
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.0053


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999











Vol. 73
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
WHODWQ
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


200
70

Y/N
Y/N

W/L
W/L
W/L












CACART; IARC; OEHHA

Drinking Water Equivalent Level
World Health Organization Drink ng Water Quality Value


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   Nitrilotriacetic acid
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 882 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

14,494
30,679
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

1
3
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chelating agent; in detergents (HSDB)
Value
8.7 days
<286
-3.8


59,100
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
Nitrofen
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 883 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Nitrofen
12291
1836755
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










0.17
49.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1983





Critical Effect










Neonatal effects
Liver - changes in liver weight




Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification


0.082
B2
2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1






1987





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


1.19
0.427
Y/N
Y/N

M8/L
W/L










Prevalence Magnitude , „
1 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Toxicology Volume 29, Issue 1-2, December 1983, Pages 1-37;
Lowest Observed Adverse Effect Level; 2-year oral study in mammal; FCTXAV Food and Cosmetics
Toxicology. (London, UK) V. 1-1 9, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year 10,427,1972
Supplemental Data










CACART; EPA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Nitrofen
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 884 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler





Amount
Released

0
25,300
# PWSs/Sites
sampled






Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






Number of
States

0
1
% PWSs/Sites
with detects






Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002








Year

2002
2002
Maximum
value of
Detects
















Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (NTP)
Value

4,400
5.534

6.74 E-05
0.7-1.2
9
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
code
BSA






Notes
BSA = biodegrades slowly with acclimation







-------
Nitromethane
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 885 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Nitromethane
2658
75525
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











12.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1967




Critical Effect











Behavioral - alteration of classical conditioning, Blood •
changes in serum composition (e.g. TP, bilirubin,
cholesterol), Biochemical - Enzyme inhibition,
induction, or change in blood or tissue levels -
transaminases




Prevalence Magnitude
6 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/pagefyear32(9),9,1967; 26-week oral study in rabbit
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1







2000











Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


29.2

Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Nitromethane
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 886 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rocket fuel; industrial solvent (HSDB)
Value

15
-0.35

2.86E-05
111,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (HSDB)







-------
N-Methylolacrylamide
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 887 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Methylolacrylamide
10095
924425
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











12.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1989




Critical Effect











Behavioral - ataxia, Liver - changes in liver weight,
Related to Chronic Data - changes in testicularweight




Prevalence Magnitude .,,„,-,
8 5 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year NTP-TR-352,1989
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)-1







1994











Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


29.2

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Methylolacrylamide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 888 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

1,121
12,306
# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States

3
13
% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Monomer; proposed for use in sunscreen (HSDB)
Value
15 days

-1.81

9.45E-12
653,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
N-Nitroso-di-n-butylamine (NDBA
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 889 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-di-n-butylamine (NDBA)
10094
924163
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0006
5.4
11
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1





1986
1987



Bladder, esophagus

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.006
Y/N
Y/N

W/L
W/L










Prevalence Magnitude
1 1 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data







OEHHA incorrectly lists EPA cancer classification as "A."


CACART; EPA; OEHHA; RAIS; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitroso-di-n-butylamine (NDBA
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 890 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released

0
5
# PWSs/Sites/
Samples
131





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0





Number of
States

0
1
% PWSs/Sites/
Samples with
detects
0





Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year

2004
2004
Maximum
value of
Detects
Not Detected













Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes



Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes


Cancer:







Research chemical (HSDB)
Value
15
642
2.63

1.32E-05
1,200
26
Units
days
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
PBT; BS = Biodegrades Slowly







-------
N-Nitrosomethylethylamine (NMEA
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 891 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
N-Nitrosomethylethylamine (NMEA)
21341
10595956
Attribute Scores
Potency Severity
8 8
Prevalence Magnitude

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d


mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification
0.0002
22
22
B2
2B
mg/L
(mg/kg-d)-1
(mg/kg-d)"1






1987





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.0016
Y/N
Y/N

W/L
W/L











3-model Categorical Prediction

HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data




IRIS





CACART; EPA; RAIS; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitrosomethylethylamine (NMEA
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 892 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
STORE!

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


Amount
Released


# PWSs/Sites/
Samples
21



Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



Number of
States


% PWSs/Sites/
Samples with
detects
0



Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Year


Maximum
value of
Detects
Not Detected







Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
National Aggregate
National Aggragate
Notes


Median value of
Detects
Not Detected
90% of
Detects
Not Detected
Units
ug/L
Notes


Cancer:







Research chemical (HSDB)
Value
38
25
0.04

1.40E-06
300,000
52
Units
days
cm3/g
unitless
cm3/g
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
PBT; BSA = Biodegrades Slowly with Acclimation







-------
N-Nitroso-N-methylurea
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 893 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
N-Nitroso-N-methylurea
9372
684935
Attribute Scores 3-model Categorical Prediction
Potency Severity
9 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











2.86




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999




Critical Effect











Musculoskeletal - changes in teeth and supporting
structures




Prevalence Magnitude
1 1 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 16-week oral study in hamster; TOPADD Toxicologic Pathology.
(c/o Dr. F.A. de a Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, Ml
48106) V.6(3/4)- 1978- Volume(issue)/page/year 27,226,1999
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


120

B2
2A
mg/L
(mg/kg-d)-1
(mgftg-d)-1
(mg/kg-d)"1







1987











Vol. 17, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.000292
Y/N
Y/N

W/L
W/L






Teratogen



OEHHA; EPA; IARC; CACART
UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   N-Nitroso-N-methylurea
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 894 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
5
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Synthetic intermediate; potential anti-neoplastic (HSDB)
Value
15 days
18.55
-0.03

9.91 E-11
14,400
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Norflurazon
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 895 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Norflurazon
30023
27314132
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.04

0.04











8,000
Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986













1977
Critical Effect
Increased cholesterol, absolute & relative liver weight
Liver; thyroid

Liver; thyroid











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 5 NLi
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 84.7
Notes
Reference Dose
Reference Dose; Sandoz-Wander, 1973; Basis NOEL 3.75 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose; Sandoz-Wander, 1973; Basis NOEL/LEL, dog, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rat; 85ARAE "Agricultural Chemicals, "Thomson, W.T., 4vols., Fresno, CA, Thomson Publications, 1976/^
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



105

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Norflurazon
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 896 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP finished water
POP finished water
PPMP finished water

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,557
# Sam pies

Amount
Released
2,459,703
0
0
# PWS/Sites/
Samples
154
288


71
#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0

1.56
% Samples with
detects

Number of
States
30
0
0
% PWS/Sites/
Samples with
detects


0

0.004
Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects




Non-cancer: 84.7
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



44
Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


Not Detected

0.21
Median value of
Detects

1.24
90% of
Detects

26.5
99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



95% of
Detects



Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA)

Cancer:







Herbicide (HSDB)
Value
60 days
5,674
2.3

3.43E-10
33.7
17
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
o-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 897 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Chloronitro benzene
3327
88733
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.001







88.9




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



methemoglobinemia







Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol), Nutritional and Gross Metabolic - weight loss
or decreased weight gain




Prevalence Magnitude
6 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Bio/Dynamics, Inc. 1985; Basis NOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 27-week oral study in mouse; NTIS National Technical
nformation Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical
nformation. Volume(issue)/page/year PB92-187608/AS
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.0097



3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1996











Vol65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7

Y/N
Y/N

W/L
W/L










RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   o-Chloronitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 898 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

315.5
2.24

9.30E-06
441

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
o-Chlorotoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 899 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Chlorotoluene
3764
95498
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.02
0.02
0.02







570




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990









1981




Critical Effect

Decreased body weight gain

Decreased body weight gain







Liver - liver function tests impaired, Kidney, Ureter,
Bladder - renal function tests depressed, Blood - other
changes




Prevalence Magnitude ,,, „
3 6 NL'
HRL Ratio(s)
NC HRL/NCOD R2 90%: 46.7
Notes
Reference Dose
Reference Dose; Gibson et al., 1974a Basis NOAEL 20 mg/kg-d, rat, UF=1000
Reference Dose
Reference Dose; Gibson et al., 1974a Basis NOAEL/LOAEL 20 mg/kg-d, rat, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 46(2), 67,1 981
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.7
140

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   o-Chlorotoluene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 900 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

15,721
24,118


32
34


0.204
0.141


0.06
0.3


16.4
52.4


0.57
0.68


3
4.4


16.4
52.4

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
HRL Ratios (HRL/NCOD R2 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309


# Sam pies

Amount
Released



# PWS/Sites/
Samples
11,883
19


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
6
0.441


% Samples with
detects

Number of
States



% PWS/Sites/
Samples with
detects
0.05
0.004


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.6
Non-cancer: 46.7
Amount Range
>10M-50M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.356


Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
24
0.0195


Median value of
Detects

0.05


90% of
Detects

0.356


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
7.9
90% of
Detects
17.5
Units for Mag
data
ug/L
Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx




Solvent; chemica intermediate; insecticide (HSDB)
Value

443
3.42

0.00357
374

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
Octamethylcyclotetrasiloxane
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 901 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Octamethylcyclotetrasiloxane
7887
556672
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















1,540
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral -tremor
Prevalence Magnitude .,, „
8 5 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0538262
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



108

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Octamethylcyclotetrasiloxane
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 902 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in PPCPs; food additive; in fermentation (HSDB)
Value
38 days
14,000
5.1

0.117
0.005
10
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
o-Dianisidine dihydrochloride
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 903 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Dianisidine dihydrochloride
26927
20325400
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











33




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Blood - other changes, Liver - changes in liver weight,
Kidney, Ureter, Bladder - changes in bladder weight




Prevalence Magnitude
1 1 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report
Series. (Research Triangle Park, NC 27709) No.206- Volume(issueypagefyear NTP-TR-372,1990.
39 week study in rat.
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


77

Y/N
Y/N

W/L
W/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   o-Dianisidine dihydrochloride
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 904 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

29
46
# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States

1
1
% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Biochemical reagent (SigmaAldrich - manufacturer)
Value
38 days





44
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
o-Dinitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 905 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Dinitrobenzene
7498
528290
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
1 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.0001












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



ncreased spleen weight













3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Cody etal. 1981; Basis NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1992













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.7

Y/N
Y/N

W/L
W/L






Reproductive




CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   o-Dinitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 906 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released

102,329
105,280
# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States

1
1
% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (HSDB)
Value

225
1.69

3.69E-07
500

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
o-Nitrotoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 907 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Nitrotoluene
3326
88722
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.01







37.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date



1986







2003




Critical Effect



Blood- elevated methemoglobin, anemia. Spleen- splenic
hemosiderosis, splenomegaly, splenic histopathology







Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude , „
6 5 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA 1986; Basis LOAEL, rat, UF=10000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 15-week oral study in rat; TXCYAC Toxicology. (Elsevier
Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ire and) V.1- 1973- Volume(issue)/page/year
183.221.2003
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.23



3
mg/L
(mgftg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1996











Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


70
0.15
Y/N
Y/N

W/L
W/L










CACART; RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   o-Nitrotoluene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 908 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released



# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for petrochemicals, pesticides, dyes and Pharmaceuticals. n(HSDB)
Value

315.5
2.3

1.25E-05
650

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
o-Toluidine hydrochloride
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 909 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
o-Toluidine hydrochloride
9161
636215
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











300




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Liver - other changes, Liver - changes n liver weight,
Related to Chronic Data - changes in testicular weight;
Kidney, Ureter, Bladder - changes in bladder weight,
Endocrine - changes in spleen weight, Nutritional and
Gross Metabolic - we ght loss or decreased weight gain




Prevalence Magnitude
2 1 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week and 13-week oral study in rat; NTPTR National
Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. 206-
Volume(issue)/page/yearNIH-96-3936
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.18
0.13

B2

mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


700
0.27
Y/N
Y/N

W/L
W/L










CACART; RAISHE; OEHHA; EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   o-Toluidine hydrochloride
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 91 Oof 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
22
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Dye intermediate (HSDB)
Value
15 days
74.04
1.32

1.98E-06
16,600
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Oxadiazon
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 911 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Oxadiazon
26706
19666309
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0036
0.005

0.005












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987














Critical Effect
ncreased level of serum protein increased liver weight,
incidence of swollen cells in central lobe of the liver.
ncr. serum proteins; ncr. liver weights

ncreased levels of serum protein and increased liver
weight













3-model Categorical Prediction
NL?
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose; OPP
Reference Dose; Rhone-Poulenc, 1981; Basis NOEL 0.5 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Rhone-Poulenc, 1981; Basis NOEL/LEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification



0.071 1


mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

25.2
0.49
Y/N
Y/N

W/L
W/L






Reproductive



CACART; EPA
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Oxadiazon
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 912 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data
POP
POP

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
28,822
# PWS/Sites/
Samples
154
317




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






% Samples with
detects

Number of
States

0
1
% PWS/Sites/
Samples with
detects






Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects



Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects






Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


99% of
Detects


Units for Mag
data
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002

Cancer:







Herbicide (HSDB)
Value

3,500
4.8

7.27E-08
0.7

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
Ozone
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 913 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Ozone
20667
10028156
Attribute Scores
Potency Severity

Prevalence Magnitude
9 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















3-model Categorical Prediction

HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Ozone
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 914 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released

0
715,830
# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States

0
20
% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Air and water dis nfectant; chemica intermediate (HSDB); Naturally-occurring gas
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
p,p'-DDE
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 915 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p,p'-DDE
2587
72559
Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.02

0.0005



12




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1984

2000



1996




Critical Effect











Liver - changes in liver weight, Immunological Including
Allergic - decrease in cellular immune response,
mmunological Includ ng Allergic - decrease in humoral
immune response




3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
NC HRL/UCMR 90%: 0.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.01
0.34
0.34

B2

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1988







IRIS





Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.1
Y/N
Y/N

W/L
W/L










CACART; EPA; RAISHE; OEHHA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   p,p'-DDE
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
    August 2009
Page 916 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
3,867



1



0.0259



3



3



3



3



3



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
POP
PPMP

HRL Ratios (HRL/UCMR 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,117

# Sam pies

Amount
Released



# PWSs/Sites/
Samples
2,672
288
688


457

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0


6

6.42

% Samples with
detects

Number of
States



% PWSs/Sites/
Sam pies with
detects
0


2.6

0.001

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected




Non-cancer: 0.03
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.062

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected


0.006

0.002

Median value of
Detects

0.0095

90% of
Detects

0.025

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected



99% of
Detects
Not Detected



Units for Mag
data
ug/L
ug/L
ug/L
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Prgram (USGS/EPA) 2001(GC/MS)





Product of degradation of DDT (HSDB)
Value
180 days
153,000
6.51

4.16E-05
0.04
1
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Paraquat
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 917 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Paraquat
16146
4685147
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.0045




0.004





0.93



25
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





1986





2001



1979
Critical Effect
Lungs, Thorax, or Respiration - other changes, chronic
pneumonitis










Lungs, Thorax, or Respiration - other changes




Prevalence Magnitude , „ ,
10 8 L' L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in dog; FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year 66, 48593, 2001
Supplemental Data


IYKEDH lyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome,
Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year 10,520,1979
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



31.5

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Paraquat
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 918 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released
6,884,630


# PWSs/Sites/
Samples
519


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0


% Samples with
detects

Number of
States
48


% PWSs/Sites/
Samples with
detects
0


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
Not Detected


Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

99% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former herbicide (HSDB)
Value
38 days
15,473-1,000,000
-4.22

<1E-09

46
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
p-Chloronitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 919 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Chloronitro benzene
4072
100005
Attribute Scores
Potency Severity
7 3
Prevalence Magnitude
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












0.177



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg
mg/kg
mg/kg
Date












ZOOS



Critical Effect












Decreased red blood cell count




3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve

Supplemental Data; Journal; Matsumoto et al., 2006 BMDL10=0.177 mg/kg/day



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1996











Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


0.41

Y/N
Y/N

W/L
M8/L










CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   p-Chloronitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 920 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes






Chemical intermed ate (HSDB)
Value

151-476
2.39


453
22
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
p-Chlorotoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 921 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Chlorotoluene
4533
106434
Attribute Scores
Potency Severity
5 3
Prevalence Magnitude
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value


0.02








1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1981




Critical Effect


Decreased body weight gain.








Brain and Coverings - recordings from specific areas of
CNS, Liver - hepatitis (hepatocellular necrosis), zonal,
Liver - liver function tests impaired




3-model Categorical Prediction
NL?
HRL Ratio(s)
NCHRL/NCODR1 90%: 70
Notes
Reference Dose
Reference Dose
Reference Dose IRIS
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in rat
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.7
140

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   p-Chlorotoluene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 922 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

15,612
21,378


27
25


0.173
0.117


0.02
0.2


6.4
22.5


0.5
0.5


2
5


6.4
22.5

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309

# Sam pies
Amount
Released



# PWSs/Sites/
Samples
11,879

0

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2

0

% Samples with
detects
Number of
States



% PWSs/Sites/
Samples with
detects
0.02

Not Detected

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
0.4

Non-cancer: 70
Amount Range
>10M-50M
>500K-1M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected

Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
3

Not Detected

Median value of
Detects
Not Detected

90% of
Detects
Not Detected

99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
1.7

90% of
Detects
2.74

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Solvent; chemica intermediate (HSDB)
Value
38 days
340
3.33

0.0044
106
20
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
p-Cresidine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 923 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Cresidine
5344
120718
Attribute Scores
Potency Severity
6 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.15


2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1987











Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.23
Y/N
Y/N

W/L
W/L










CACART; OEHHA; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   p-Cresidine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 924 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500K-1M
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; dye intermediate (HSDB)
Value
38 days
53
1.74

1.20E-07

36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
p-Dinitrobenzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 925 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Dinitrobenzene
4094
100254
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.0001












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



ncreased spleen weight












Prevalence Magnitude ,,, „
1 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Codyetal 1981; Basis NOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.7

Y/N
Y/N

W/L
W/L











CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   p-Dinitrobenzene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 926 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released

28,100
28,71 1
# PWSs/Sites
sampled


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects


Number of
States

1
1
% PWSs/Sites
with detects


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; dye constituent (HSDB)
Value

221
1.46

3.69E-07
69

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Pentabromodiphenyl ethers
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 927 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentabromodiphenyl ethers
31963
32534819
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002

0.002
0.007











Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986


2004











Critical Effect

Induction of hepatic enzymes

nduction of hepatic enzymes
Hepatic











Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Carlson, 1980; Basis NOAEL 1.77 mgflsg-d, rat, UF=1000
Reference Dose
Reference Dose; Carlson, 1980; Basis NOAEL/LOAEL, rat, UF=1000
Minimal Risk Level; Int.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1






1990













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pentabromodiphenyl ethers
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 928 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released



# PWSs/Sites
sampled



#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects
Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame retardant (HSDB)
Value

30,500
7.66

3.55E-06
0.000079

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant







-------
Pentachloroethane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 929 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentachloroethane
2699
76017
Attribute Scores
Potency Severity
4 3
Prevalence Magnitude
4 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












126



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect












increased glucose excretion




3-model Categorical Prediction
NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level

Lowest Observed Adverse Effect Level
Supplemental Data, NTP, NIH Pub 96-3935, 1996



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1999











Vol. 41, Suppl. 7; Vol. 71
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



294

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 ~B cancer risk was used.

-------
    Pentachloroethane
    CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
    August 2009
Page 930 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released

5
865
# PWSs/Sites/
Samples
429



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0



% Samples with
detects


Number of
States

1
4
% PWSs/Sites/
Sam pies with
detects
0



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range
>1M-10M
>10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
Not Detected



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

90% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.asox





ndustrial solvent; chemical intermediate (HSDB)
Value
180 days
1 1 7-244



500
13
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reclacitrant (PBT)







-------
Pentaerythritol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 931 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentaerythritol
5114
115775
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









100




2,000

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Diarrhea






Prevalence Magnitude ,,, „
8 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pentaerythritol
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 932 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for resins, paints, Pharmaceuticals, insecticides (HSDB)
Value

9
-1.69

4.10E-10
72,300
34
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
Pentaerythritol dibromide
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 933 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentaerythritol dibromide
14700
3296900
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











100




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1980




Critical Effect











Sense Organs and Special Senses (Eye) - effect, not
otherwise specified




Prevalence Magnitude ,,, „
5 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; JCTODH Journal of Combustion Toxicology. (Westport,
CT) V.3-9, 1976-82. Volume(issue);page/year 7,77,1980
Supplemental Data;



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1



















No quantitative data for the cancer endpoint were identified; Cancer classifications were used for
screening, but no related quantitative cancer risk data were identified for potency scoring."
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


233

Y/N
Y/N

M8/L
W/L










IARC; CACART

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pentaerythritol dibromide
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 934 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame retardant; polymer intermediate (HSDB)
Value

420
2.29

4.10E-09
38,000
34
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (BIODEG)







-------
Pentanal
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 935 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pentanal
4865
110623
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













3,200


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect













No effect reported other than lethality.


Prevalence Magnitude
4 8 Li
HRL Ratio(s)
NC HRL/NAWQA 90%: 26.4
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Sax, N.I. Dangerous Properties of Industrial Materials. 6th ed. New York, NY: Van Nostrand
Reinhold, 1984., p. 2716


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



224

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pentanal
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 936 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF ICR




# PWSs/Sites
sampled
236




#with Detects
1




% PWSs/Sites
with detects
0.42




Mean value of
Detects
8.5




Maximum
value of
Detects
8.5




Median value of
Detects
8.5




90% of
Detects





99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Mean value of
Detects

Non-cancer: 26.4
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes









National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; rubber additive (HSDB)
Value
8.7
1,040
1.31

0.000147
13.5
41
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BF = Biodegrades fast with acclimation







-------
Phenolphthalein
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 937 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenolphthalein
2743
77098
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











400
400



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect











Liver - tumors, Tumorigenic - active as anti-cancer agent
Hyperplasi of the parathyroid, fibrous osteodystrophy
of the bone, hypersplais of the thyroid advanced
nephropathy - clear evidence of cancer in mice and
male rats-some evidence in female rats.



Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTIS National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/paqe/year
Supplemental Data; NTP report TR-465.



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







2000











Vol. 76; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


933

Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phenolphthalein
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 938 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies


Amount
Released



# PWSs/Sites
sampled




#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects


Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year

1994






Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects





90% of
Detects





99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical reagent; medical indicator (HSDB)
Value
38 days
490
2.41

9.00E-16
400
13
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Phenyl ether
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 939 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenyl ether
4208
101848
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















2,450
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral - food intake (animal), Behavioral - muscle
weakness, Gastrointestinal - other changes
Prevalence Magnitude ,,, „
7 5 NL'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/pagefyear OTS0518143
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phenyl ether
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 940 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Synthetic intermediate; in PPCPs (Merck Index, 1983)
Value

1,950
4.21

0.00028
18
ir
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Phenylmercury acetate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 941 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenylmercury acetate
2433
62384
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00008

0.00008







0.625



13.3
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1985









2001



1980
Critical Effect

Kidney damage at the LOAEL, kidney lesions at higher
doses









Kidney, Ureter, Bladder - other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 5 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Fitzhugh et al., 1950; Basis NOAEL 0.0084 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Fitzhugh etal., 1950; Basis NOAEL/LOAEL, rat, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; HBPTO Handbook of pesticide
toxicology. Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1380,2001
Supplemental Data


YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho,
Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year 22,291,1980
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.56

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phenylmercury acetate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 942 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; disinfectant; drug preservative (HSDB)
Value

171.8
0.71

5.65E-10
4,370

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Phenytoin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 943 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phenytoin
2317
57410
Attribute Scores 3-model Categorical Prediction
Potency Severity
5
Prevalence Magnitude
1 5
Incomplete data for scoring HRL Ratio(s)
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
Supplemental ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











20.5
5
4.3



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

















Critical Effect











Nutritional and Gross Metabolic - weight loss or decreased
weight gain





NC HRL/Vanderford MAX: 68.8
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; NTPTR National Toxicology Program Technical Report Series.
(Research Triangle Park, NC 27709) No.206- Vo ume(issue)/page/year NTP-TR-404,1993
Maximum Recommended Daily Dose (MRDD)
Minimum Therapeutic Dose (MTD)



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
DSSTOX TD50
EPA Carcinogen classification
ARC Carcinogen Classification



59.1

2B
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
mg/kg-d







1996









Tumorigenic Dose - 50

Vol. 66; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potencv scorinq.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

11.7

Y/N
Y/N

M8/L
W/L






Developmental



CACART
CACART; UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phenytoin
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 944 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
Snyder, 2008
Snyder, 2008
Vanderfordetal., 2006
HRL Ratios (HRL/Vanderford MAX)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released

0
15,981
# PWSs/Sites/
Samples






#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects






% Samples with
detects

Number of
States

0
1
% PWSs/Sites/
Samples with
detects






Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects



Non-cancer: 68.8
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
0.032
0.04
0.17



Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects



99% of
Detects



Units for Mag
data



Cancer:



Notes
Finished Drinking Water Monitoring; Snyder, Shane A. 2008. Ozone:
Science and Engineering. 30(1): 65-69.
Raw Drinking Water Monitoring; Snyder, Shane A. 2008. Ozone:
Science and Engineering. 30(1): 65-69.
Ambient Water Monitoring; Vanderford etal., 2006 Env. Sci. &Technol.
40(23), pp. 7312-7320.




Pharmaceutical (ChemlDPIus)
Value
38 days

2.47

1.02E-11
32
16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slowly with acclimation







-------
Phosmet
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 945 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phosmet
9544
732116
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.011
0.02

0.02

0.01









26
Units
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986



1998









1969
Critical Effect
RBC & serum ChE inhibition
Red. Body weight; liver cell vacuolization; ChE inhibition

Reduced bodywt; liver cell vacuolization; Cholinerase
inhibition











Behavioral - somnolence (general depressed activity),
Behavioral - muscle contraction or spasticity, Lungs,
Thorax, or Respiration - dyspnea
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
NC HRL/GWC EEC: 193
Notes
Reference Dose
Reference Dose; Stauffer Chemical 1967; Basis NOEL 2 mg/kg-d, rat, UF=100
Reference Dose
Reference Dose; Stauffer Chemical 1967; Basis NOEL/LEL, rat, UF=101
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71.
Discontinued. Volume(issue)/page/year 34(1-3), 192, 1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



77

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phosmet
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 946 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
CAL DHS

# Sam pies

Amount
Released
1,333,468


# PWSs/Sites/
Samples
134
381

11
OPP Estimated Environmental Concentration

HRL Ratios (HRL/GWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0
0

% Samples with
detects

Number of
States
40


% PWSs/Sites/
Sam pies with
detects


0
0

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Not Detected
Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


Not Detected
Not Detected
Surface water chronic:

Non-cancer: 193
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
Not Detected
99% of
Detects


Not Detected
Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) Ambient and finished
water; method 9002 (GC/MS)
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx
Ground water chronic: 0.4 ug/L

Cancer:







nsecticide (HSDB)
Value
38 days
42.9
2.78

8.39E-09
24.4
19
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Phosphorus
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 947 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phosphorus
19191
7723140
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.00002
0.00002
0.00002
0.0002






0.00005




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990


1997






1989




Critical Effect

Parturition mortality; forelimb hair loss









Behavioral - alteration of classical conditioning




Prevalence Magnitude
10 10
HRL Ratio(s)
NC HRL/NIRS 90%: 0.00037
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.015 mg/kg-d, UF = 1000, rat, oral (Condray, 1985)
Reference Dose
Reference Dose; Basis = NOAEL/LOAEL, MF = 1 , UF = 1 000, rat (Condray, 1 985)
Minimal Risk Level; Int., oral, UF = 100, Endpoint = repro.
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1






1990













Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.0005
0.14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Phosphorus
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 948 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



392



39.6



42



555



104



381



1,576
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
8,090

# Sam pies

Amount
Released

4,457
31,102
# PWSs/Sites
sampled

5,432

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

67.1

% Samples with
detects

Number of
States

4
16
% PWSs/Sites
with detects

1

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.00037
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002
Former pesticide; chemical intermediate; as ammunit
Value

14.3
-0.27
3.5
0.0244
205,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code










11,000

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

44

Median value of
Detects

270

90% of
Detects

1,909

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





on (HSDB)
Notes








-------
Phthalic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 949 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Phthalic acid
3343
88993
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










105
0.56




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1967




Critical Effect










Decreased body weight gain
Blood - changes in serum composition (e.g. TP, bilirubin,
cholesterol)




Prevalence Magnitude
5 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal - Toxicology Letters 93 (1997) 109-115. Ema, et al.
Lowest Observed Adverse Effect Level; 26-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(8), 12,1 967
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



733

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Phthalic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 950 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year

1994





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide (HSDB)
Value
2.5-5 weeks
2-31
0.73

2.00E-11
6,965
36
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (HSDB)







-------
Piperidine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 951 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Piperidine
4890
110894
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















22.4
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1975
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „ ,
5 5 Li~L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New
ndustrial Chemical Substances. For English translation, see TNICS. (Izdatel'stvo Meditsina,
Moscow, USSR) No.1- 1961- Volume(issue);page/year 14,90,1975
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N

M8/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Piperidine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 952 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; rubber accelerator (HSDB)
Value


0.84

4.35E-06
1,000,000
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
p-Nitrosodiphenylamine
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 953 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Nitrosodiphenylamine
6319
156105
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
1 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL-NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


0.022

B2
3
mg/L
(mg/kg-d)"1
(mg/kg-d)-'
(mg/kg-d)"1







1987










Cited by OEHHA
Vol. 27, Suppl. 7
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



1.59
Y/N
Y/N

W/L
W/L










CACART; OEHHA; EPA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentrat
on at the 1 0 "6 cancer risk was used.

-------
   p-Nitrosodiphenylamine
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 954 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release -total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; food additve; rubber accelerator (HSDB)
Value
38 days

3.16

1.10E-08
17.3
16
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
p-Nitrotoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 955 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Nitrotoluene
4071
99990
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.01







55




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



splenic lesions







Blood - leukemia, Tumorigenic - active as anti-cancer
agent




Prevalence Magnitude
65 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; NTP 1992; Bass LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 105-week oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year NIHNo.01-4432
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.017



3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1996











Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer




2.06
Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   p-Nitrotoluene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 956 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
K0c« Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for dyes (HSDB)
Value

309
2.37

5.63E-06
442

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Poly(dimethyl diallyl ammonium
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 957 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Polyfdimethyl diallyl ammonium chloride)
29130
26062793
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











290



1,720
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988



1988
Critical Effect











Liver - other, blood - changes in spleen



Behavioral - somnolence (general depressed activity),
Behavioral - convulsions or effect on seizure threshold,
Lungs, Thorax, or Respiration - respiratory depression
Prevalence Magnitude ,,, _
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; QISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 53(3),66,1 988
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 53(3), 66,1988
Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



678

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Poly(dimethyl diallyl ammonium
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 958 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M

Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





PPCPs (NLM/NIH)
Value
1 5 days





39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Potassium
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 959 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Potassium
18836
7440097
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










67
0.94




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988




Critical Effect










No effect
Cardiac - changes in heart weight, Gastrointestinal - other
changes, Blood - changes in cell count (unspecified)




Prevalence Magnitude ,,, „
10 10 NL'
HRL Ratio(s)
NCHRL/NIRS90%: 0.08
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; DRI pg.235; NAS
Lowest Observed Adverse Effect Level; 180-day oral study in rat; VCVN1 "Vrednie chemichescie
veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic
substances containing I-IV group elements), Filov V.A., Chimia, 1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



469

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Potassium
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 960 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



958



96.9



311



23,955



1,860



5,939



15,422
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites/
Samples
10,193



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
9,307



% Samples with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
91.3



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
60

Non-cancer: 0.08
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
3,900,000



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
2,790

90% of
Detects
5,000

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Laboratory reagent (HSDB)
Value







Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
p-Phenetidine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 961 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
p-Phenetidine
6322
156434
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









10

0.242



530
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1978



1981
Critical Effect









Bone marrow toxicity, methemaglobinemia, spleen toxicity

Blood - normocytic anemia, Blood -
methemoglobinemia-carboxyhemoglobin, Blood -
other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
58 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 9-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (WO Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-
1936- Volume(issue)/pagefyear 43(1 ),92, 1978; LOAEL was used forpotency scoring because it was
lower than the NO(A)EL from other studies.
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases.
(V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information,
see MTPEEI Vo ume(issue)/page/year 25(8), 50,1981
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.56

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   p-Phenetidine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 962 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
XIM-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate (Merck Index, 1983; OECD SIDS)
Value


1.24

1.50E-07
7,510
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrqades sometimes/recalcitrant (BIODEO)







-------
Prometon
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 963 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Prometon
11873
1610180
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.015
0.015
0.015







15




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1886
1986








2001




Critical Effect

No treatment related effects observed. Decreased
Potency Score by one integer









Nutritional and Gross Metabolic - weight loss or decreased
weight gain




Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 1 ,438
Notes
Reference Dose
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15 mg/kg-d, rat, UF=1000. IRIS also reports
maternal toxicity in a study not used for the RfD derivation; Severity scored on this critical effect.
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15, rat, UF=1000
Reference Dose; Ciba-Geigy, 1982a; Basis NOAEL 15, rat, UF=1000
Minimal Risk Leve
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; HBPTO Handbook of pesticide toxicology.
Robert Krieger ed, Academic press, 2001 Volume(issue)/page/year 2,1512,2001
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


0.5
105

Y/N
Y/N

W/L
W/L


1988









Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Rela ive Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
      Prometon
      CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 964 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300



0



0



Not Detected



Not Detected



Not Detected



Not Detected



Not Detected



Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS
POP
POP
PPMP

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1/2, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,128


# Sam pies


Amount
Released



# PWSs/Sites/
Samples
609
288
553


1,627


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0

26
145

22.8


% Samples with
detects
2.92
0.49
Number of
States



% PWSs/Sites/
Sam pies with
detects
0

4.7
63.6

0.0004


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected

0.0025


Non-cancer: 1,438
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



40


Maximum value
of Detects


Year
1997
2004
2004
Maximum value
of Detects
Not Detected

0.0025
0.103

0.014


Median value of
Detects
0.15
0.16
0.073


90% of Detects


0.381


99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected



99% of Detects
Not Detected



Units for Mag
data
ug/L
ug/L
ug/L
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
te.aspx
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001 (GC/MS)





Herbicide (HSDB)
Value
60 days
156
2.99

3.18E-09
750
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Propanenitrile
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 965 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propanenitrile
4591
107120
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










20


35.8


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1996


Critical Effect










Maternal toxicity and slight fetotoxicity





Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; Journal -Johansen etal, 1986
Lowest Observed Adverse Effect Level
Supplemental Data
Lewis, R.J., Dangerous Properties of Industrial Materials, 9th Ed., Vol. 1-3, NY, NY, Van Nostrand
Reingold, 1996., p 2799


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Propanenitrile
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 966 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; industrial solvent (HSDB)
Value
1 5 days
29
0.16

3.70E-05
130,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Propargite
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 967 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propargite
13082
2312358
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.04
0.02

0.02

0.01









1,480
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990



1999









1969
Critical Effect
Decreased body weight & body weight gain, increased
mortality. Q1* 0.0033 (mg/kg-day)-1 . See CAR














Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
64 L'
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 477
Notes
Reference Dose
Reference Dose; Uniroyal Chemical, 1966, 1982; Basis NOEL 22.5 mg/kg-d, dog, UF=1000
Reference Dose
Reference Dose; Uniroyal Chemical, 1966; Basis NOEL, dog, UF=1000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959- Volume(issue)/page/year 14,515,1969
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification



0.0033


mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1

















OPP


Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

280

Y/N
Y/N

W/L
W/L






Developmental



CACART
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Propargite
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 968 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,108


# Sam pies

Amount
Released
2,538,969
0
253
# PWSs/Sites/
Samples
288
688


62


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0

0.872


% Samples with
detects

Number of
States
30
0
1
% PWSs/Sites/
Samples with
detects


0

0.0026


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Not Detected

Non-cancer: 477
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



20


Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


Not Detected

0.044


Median value of
Detects

0.587


90% of
Detects

3.5


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
99% of
Detects


Not Detected
Units for Mag
data
ug/L
ug/L
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)

Cancer:







nsecticide (HSDB)
Value
60 days
138,000
5

4.16E-08
0.5
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Propargyl alcohol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 969 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propargyl alcoho
4597
107197
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.002

0.002











20
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1990













1982
Critical Effect

Increased liver & kidney weights, megalocytosis of the
iver

iver, kidney











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
66 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S.EPA, 1987; Basis NOAEL 5 mg/kg-d, rat, UF=3000
Reference Dose
Reference Dose; U.S.EPA, 1987; Basis NOAEL/LOAEL, rat, UF=3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds.,
New York, John Wiley & Sons, Inc., 1978-82. Vo . 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
Volume(issue)/page/vear 2C, 4672, 1982
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



14

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Propargyl alcohol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 970 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
64,096
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
6
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Corrosion inhibitors; in pharmaceutcals; chemical intermediate (HSDB)
Value

1.325
-0.38

1.15E-06
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF/BST






Notes
BF = Biodegrades fast; BST = Biodegrades sometimes/reca citrant (BIODEG)







-------
Propionaldehyde
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 971 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propionaldehyde
5508
123386
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1971
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 8 L
HRL Ratio(s)
NC HRL/DBP ICR MED: 8.2
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year
21MAY19T1
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



56

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Propionaldehyde
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
    August 2009
Page 972 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBF ICR



# PWSs/Sites
sampled
236



#with Detects
4



% PWSs/Sites
with detects
1.69



Mean value of
Detects
7.2



Maximum
value of
Detects
9.9



Median value of
Detects
6.8



90% of
Detects




99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/DBP ICR MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released

9,607
699,803
# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States

4
15
% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer: 8.2
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L
Units for Mag
data
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes




Notes



National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; chemical intermediate (HSDB)
Value
15 days
50
0.59

7.30E-05
306,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slowly







-------
Propionic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 973 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propionic acid
2861
79094
Attribute Scores
Potency Severity
3 6
Prevalence Magnitude
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










735




1,640
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect










hyperplasia of the esophagus; nitrite in urine




Details of toxic effects not reported other than lethal dose
value

3-model Categorical Prediction
NL? - L?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPP RED
Lowest Observed Adverse Effect Level
Supplemental Data


Rat; GISAAA G giena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 39(4), 86,1974
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



5,145

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Propionic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 974 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
100M-500M
100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L




ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Pesticide; food additive; chemica intermediate (HSDB)
Value
up to 21 days
36
0.33


1,000,000
sr
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (HSDB)







-------
Propoxyphene hydrochloride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 975 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propoxyphene hydrochloride
11929
1639607
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











207



82
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1971



1971
Critical Effect











Liver - changes in liver weight, Blood - changes in
erythrocyte (RBC) count, Nutritiona and Gross
Metabolic - weight loss or decreased weight gain



Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - respiratory depression
Prevalence Magnitude ,,,
1 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; TXAPA9 Toxicology and Applied Pharmacology.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year
19,452,1971
Supplemental Data


Rabbit; TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN
55802) V.1- 1959- Volume(issue)/page/year 19,445,1971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



483

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Propoxyphene hydrochloride
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 976 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

10K-500K
Units
Ibs/yr
Ibs/yr
Year

1990





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L




ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





d-isomer as veterinary medicine (HSDB - CASRN 469-62-5)
Value
38 days

4.18



12
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)

Kow for d-propoxyphene





-------
Propylene glycol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 977 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glycol
2323
57556
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.5







5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect



hematological changes







Blood - normocytic anemia, Blood - other hemolysis with or
without anemia




Prevalence Magnitude
10 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Bauer et al; Basis LOAEL, cat, UF = 3000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in dog; VCVGK "Vrednie chemichescie
veshestva, galogen I kislorod sodergashie organ cheskie soedinenia". (Hazardous substances. Galogen
and oxygen containing substances), Bandman A.L. etal., Chimia, 1994
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

3,500

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Propylene glycol
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 978 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L




ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food additive; in PPCPs; as coolant (HSDB)
Value

1
-0.92

1.31E-10
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Propylene glycol 1-methyl ether
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 979 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glycol 1 -methyl ether
4655
107982
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.7











5,000
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1972
Critical Effect



Histo pathology











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
88 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; USEPA, 1 991 ; Basis NOEL = 1 mg/kg-d, rat, UF = 1 000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Dog; ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(ssue)/page/year 22,569,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

4,900

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Propylene glycol 1-methyl ether
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 980 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n paints and coatings; pesticide so vent (HSDB)
Value
1 5 days
1
-0.49

9.20E-07
1,000,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Propylene glycol monomethyl eth
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 981 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glyco monomethyl ether acetate
4706
108656
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









300





8,532
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Decreased body weight gain





Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


DOWCC Dow Chemical Company Reports. (Dow Chemical USA, Health and Environment Research,
Toxicology Research Lab., Midland, Ml 48640) Vo ume(issue)/page/year MSD-1582
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,100

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Propylene glycol monomethyl eth
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 982 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Units for Mag
data
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units

Cancer:



Notes





Pesticide inert (EPA OPP)
Value
15

0.56

3.44E-06
198,000
45
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Propylene glycol mono-t-butyl
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 983 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Propylene glyco mono-t-butyl ether
37358
57018527
Attribute Scores
Potency Severity

Prevalence Magnitude
5 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction

HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L










Equivocal evidence of carcinogenicity
n male rats; clear evidence in male/female mice (NTP)

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Propylene glycol mono-t-butyl
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 984 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L


ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; in PPCPs; in paints and coatings (HSDB)
Value

5
0.87

4.73E-06
173,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST= biodegrades sometimes / reca citrant (HSDB)







-------
Pyrazon
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
    August 2009
Page 985 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyrazon
12037
1698608
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.18










66



493
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1992



1992
Critical Effect
Decreased body weight & body weight gain










Liver - changes in liver weight, Endocrine - changes in
thyroid weight, Biochemical - Enzyme inhibition, induction,
or change in blood or tissue levels - transaminases



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,3171,1992
Supplemental Data


Guinea pig; NNGADV Nippon Noyaku Gakkaish . Journal of the Pesticide Science Society of Japan.
(Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
Volume(issue)/page/year 1 7,S1 71 ,1 992
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,260

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Pyrazon
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 986 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
118,294


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
9


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (HSDB)
Value
38 days
33-346
1.14

6.50E-12
400
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrdaes slow with acclimation (PBT)







-------
Pyridine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 987 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyridine
4887
110861
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.001

0.001







0.255




Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987









1958




Critical Effect

ncreased liver weight









Blood - change in clotting factors, Related to Chronic Data -
death




Prevalence Magnitude
99 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; U.S.EPA, 1986; Basis NOAEL = 1 mg*g-d, rat, UF = 1000
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 14-week oral study in rat; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 23(7), 30,1 958
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7

Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pyridine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 988 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

526
1,302,842
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

6
21
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent; chemica intermediate; food additive; unreg stered pesticide (HSDB)
Value

33
0.65

1.10E-05
1,000,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA/BST






Notes
BFA = Biodegrades fast with acclimat on/BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
Pyridine, pentachloro-
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
    August 2009
Page 989 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Pyridine, pentachloro-
12850
2176627
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















435
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral -somno ence (general depressed activity),
Behavioral -convulsions or effect on seizure threshold
Prevalence Magnitude
67 Li
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume issue)/page/year OTS0536503, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Pyridine, pentachloro-
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
    August 2009
Page 990 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemica
Value
1 80 days
2,000
3.53

6.30E-03

16
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
Quartz (SiO2)
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 991 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quartz (Si02)
24322
14808607
Attribute Scores 3-model Categorical Prediction
Potency Severity
1 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











120,000




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994




Critical Effect











Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - other changes




Prevalence Magnitude
1
Incomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect LevelEPASR United States Environmental Protection Agency,
Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
Washington, DC 20460) History unknown. Vo ume(issue)/page/year#86940001000,1994. Rodent -
rat.
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10^
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





1
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


280,000

Y/N
Y/N

W/L
W/L










IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Quartz (SiO2)
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
    August 2009
Page 992 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10K-50K
>10K-50K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Naturally-occurring mineral
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
Quizalofop
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 993 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Quizalofop
76725
76578126
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Prevalence Magnitude
10 8
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Quizalofop
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 994 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
340,818


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
35


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Derivative of the herbicide quizalofop-ethyl (HSDB)
Value
38 days

3.57


0.3
12
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Santoflex 13
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 995 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Santoflex 13
9730
793248
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









6

62.3



3,580
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1990
Critical Effect









Liver cell enlargement or alteration

Liver - changes in liver weight, Blood - normocytic anemia,
Blood - changes in leukocyte (WBC) count



Sense Organs and Special Senses (Eye) - effect, not
otherwise specified, Behavioral - food intake (animal),
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude ,,, _
7 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0545431
Supplemental Data


rodent-rat; ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary
Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year 1,67,1990
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



42

Y/N
Y/N

M8/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Santoflex 13
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 996 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Antioxidant/antiozonant (HSDB)
Value
38 days





11
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Sethoxydim
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 997 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sethoxydim
65122
74051802
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.14
0.09

0.09











3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1991
Critical Effect
Liver effects: hepatocellular hypertrophy & fatty
degeneration
Mild anemia in males

Mild anemia in males











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
10 7 L
HRL Ratio(s)
No water data
Notes
Reference Dose, BASF Corporation, 1984
Reference Dose, BASF Corporal on, 1984, NOEL = 9.41 mg/kg-d, dog, UF = 100
Reference Dose
Reference Dose, BASF Corp., 1984, NOEL/LEL, dog, UF=100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C274,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



980

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sethoxydim
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
    August 2009
Page 998 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
1,717,271
0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
48
0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Herbicide (HSDB)
Value
38 days
2,845
4.38

2.16E-11
25
11
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Silicon
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
    August 2009
Page 999 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Silicon
18845
7440213
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















3,160
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
10 10
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No. ?-57, 1948-77. Discontinued.
Volume(issueypage/year53A,21,1974, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Silicon
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1000 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



989



100



0.26



98.9



18.1



42.1



67.5
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
mg/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; alloys (HSDB)
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
Sodium
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1001 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium
18847
7440235
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











9.38




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988




Critical Effect











Cardiac - changes in heart weight, Gastrointestinal -
other changes, Blood - changes in cell count
unspecified)




Prevalence Magnitude , „
10 10 L
HRL Ratio(s)
NCHRL/NIRS90%:0.14
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, VCVN1 "Vrednie chemichescie veshestva.
Neorganicheskie soedinenia e ementov I-IV groopp" (Hazardous substances. Inornanic
substances containing l-IVgroup elements), Filov V.A., Chimia, 1988. Volume(issue)/page/year -
,36,1988
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
CADW
EPA HA
Health Reference Level (HRL)2 cancer



21.9
200
20

Y/N
Y/N

M8/L
mg/L
mg/L
M8/L





F'03










Drinking Water Equivalent Level

Aesthetic Objective (AO)
Health Advisory Status For individuals on a SOOmg.day restiricted sodium diet

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
     August 2009
Page 1002 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water


989


989


100


0.907


1,541


16.4


160


498
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total

CAL DHS

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites/
Samples
11,845


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
11,826



% Samples with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
99.8



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
7

Non-cancer: 0.14
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects
173,000,000



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
mg/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


90% of
Detects


Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Chemical intermed ate; alloys; sem conductors (HSDB)
Value

14.3
-0.77

0.0246
445,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegrades sometimes/recalcitrant







-------
Sodium azide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1003 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium azide
29534
26628228
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.004

0.004






5
0.25




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986









1999




Critical Effect

Clinical signs (e.g., hunched postures) & reduced body
weight

Clinical signs & reduced body weight







Cardiac - EKG changes not diagnostic of specified effects,
Liver - liver function tests impaired, Kidney, Ureter,
Bladder - other changes in urine composition




Prevalence Magnitude
3 6 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; NCI, 1981; Basis NOEL = 5 mg/kg-d, rat, UF = 1,000
Reference Dose
Reference Dose; NCI, 1981; Bas s NOAEL/LOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 26-week oral study in unspecified mammal; STGNBT
"Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh
Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia,
zd AT 1 999 Volume(issue)/page/year -, 1 73, 1 999
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



28

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium azide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1004 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
66,425
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
3
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; herbicide (HSDB)
Value

1.342
0.16

7.78E-05
36,700

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Sodium benzoate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1005 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium benzoate
7550
532321
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1,505
2,090


1,600
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991
1993


1986
Critical Effect











Behavioral - convulsions or effect on seizure threshold,
Nutritional and Gross Metabolic - weight loss or decreased
weight gain, Related to Chronic Data - death
Increased liver and kidney weight, increased serum
albumin and total protein, increased GGT, enlarged
hepatocytes with glassy cytoplasm


Behavioral - changes in motor activity (specific assay),
Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude ,,, „
7 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 13-week oral study in rat; TRENAF Kenkyu Nenpo-Tokyo-toritsu
Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-
toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50-
Volume(issue)/page/year42,285,1991
Supplemental Data, Fujitani, 1993


rodent-mouse; GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 51(1), 75,1986
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

14,630

Y/N
Y/N

M8/L
W/L






Teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium benzoate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1006 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food and pharmaceutical preservative; medication (HSDB)
Value
1 5 days




556,000
41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Sodium bromide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1007 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium bromide
19109
7647156
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.129



3,500
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1972



1935
Critical Effect











Liver -changes in liver weight, Biochemical -Enzyme
inhibition, induction, or change in blood or tissue
evels - transaminases



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
5 10 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Qigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 37(1), 13,1972, rodent-rabbit
Supplemental Data


rat study; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co.,
428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 55,200,1935
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.3

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium bromide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1008 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1990
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Photographic chemical; in chemica synthesis (HSDB)
Value





909,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Sodium chlorate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1009 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium chlorate
19266
7775099
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.03










1.36



1,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1985



2001
Critical Effect
Thyroid hypertrophy










Blood - pigmented or nucleated red blood cells, Blood -
changes in erythrocyte (RBC) count, Nutritional and Gross
Metabolic - weight loss or decreased weight gain



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
9 8 L
HRL Ratio(s)
NC HRL/SWC EEC: 304
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 1-year oral study in rat; JEPOEC Journal of Environmental
Pathology, Toxicology and Oncology. (Chem-Orbtal, POB134, Park Forest, IL 60466) V.5(4)- 1984-
Volume(issue)/page/year 6(1), 105,1 985
Supplemental Data


rodent-rat; HBPTO Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
Volume(issue)/page/year2,1412,2001
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



210

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium chlorate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1010 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies

Amount
Released
7,261 ,557



OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
16





Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997



Surface water chronic: 0.69 ug/L

Non-cancer: 304
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic:

Cancer:







Herbicide; oxidizing agent in PPCPs and industrial processes (HSDB)
Value





75,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Sodium chloroacetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1011 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium chloroacetate
15383
3926623
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











60



95
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991



1941
Critical Effect











Liver - changes in liver weight, Kidney, Ureter, Bladder
changes in bladder weight, Blood - changes in
eukocyte (WBC) count



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 90-day oral study in rat; TXCYAC Toxicology. (Elsevier
Scientific Pub. Ireland, Ltd., POB85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year
67,171,1991
Supplemental Data


rodent-rat; JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V. 18-31, 1936-49.
For publisher information, see AEHLAU. Volume(ssue)/page/year 23,78,1941
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Sodium chloroacetate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1012 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemica
Value
1 5 days





41
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Sodium dimethyldithiocarbamate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1013 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium dimethyldithiocarbamate
5680
128041
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












114


300
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date












1976


2000
Critical Effect












Developmental toxicity


Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
77 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplimental Data, Toxicology and Applied Pharmacology VolumeSS, Issue 1, January 1976,
Pages 83-94


rodent- rabbit; TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia)
History Unknown Volume(issue)/page/year (3), 34,2000
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

266

Y/N
Y/N

W/L
W/L






developmental




CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Sodium dimethyldithiocarbamate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1014 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

31,009
129,318
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

3
9
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial antimicrobial (HSDB)
Value
0.01 3-1. 08 days
2.2



1,000,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Sodium dodecylbenzenesulfonate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1015 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium dodecylbenzenesulfonate
28421
25155300
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











101



438
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1975



1972
Critical Effect











Liver - other changes, Blood - changes in serum
composition (e.g. TP, bilirubin, cho esterol), Nutritiona
and Gross Metabolic - changes in iron



Sense Organs and Special Senses (Eye) - lacrimation,
Behavioral - somno ence (general depressed activity),
Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude
7 5 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AECTCV Archives of Environmental Contamination and
Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944)
V.1- 1973- Volume(issueypage/year 3,1 15,1 975
Supplemental Data


rodent- rat; TRENAF Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo
Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1 , 3-chome,
Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- Volume(issue)/page/year 24,397,1972
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



236

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium dodecylbenzenesulfonate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1016 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Detergent; in pesticide formulations (HSDB)
Value
1 5 days
111
0.45

6.27E-08
800,000
21
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Sodium fluoroacetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1017 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium fluoroacetate
2445
62748
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00002
0.00002

0.00002







0.0216



0.066
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1960



1951
Critical Effect
Histopathology & decreased size & weight of testes
and epididymides
ncr. heart weight; reproductive effects in male

increased heart wt, decreased testiswt, altered
spermatogenesis







Related to Chronic Data - death



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
1 1 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose, U.S. EPA, 1988, Basis NOAEL = 0.05 mg/kg-d, rat, UF = 3,000
Reference Dose
Reference Dose; USEPA, 1988, oral study in rats, UF = 3,000, Basis NOAEL/LOAEL
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 30-day study in domestic mammal; JCPTA9 Journal of
Comparative Pathology and Therapeutics. (Liverpool, UK) V.1-74, 1883-1964. For publisher information,
see JCVPAR. Volume(issue)/page/year 70,145,1960
Supplemental Data


mammal- dog; JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins
Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year 101,82,1951
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.14

Y/N
Y/N

W/L
W/L






Male reproductive




CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium fluoroacetate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1018 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
0
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
0
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2002
2002
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Rodenticide (HSDB)
Value

1.201
-3.78

1.09E-06
111,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (HSDB)







-------
Sodium hypochlorite
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1019 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium hypochlorite
19138
7681529
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
Scores based on parent
HEALTH EFFECTS DATA1 See parent Sodium
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











9.38



5,800
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1988



1986
Critical Effect











Cardiac - changes in heart weight, Gastrointestinal -
other changes, Blood - changes in cell count
(unspecified)
(for parent sodium)



Behavioral - changes in motor activity (specific assay),
Gastrointestinal - other changes
Prevalence Magnitude , „
10 10 L
Scores based on parent HRL Ratio(s)
NC HRL/NIRS 90%: 0.14 (HRL and NIRS based on
parent Sodium)
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, VCVN1 "Vrednie chemichescie veshestva.
Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic
substances containing I-IV group elements), FilovV.A., Chimia, 1988. Volume(issueypage/year-
,36,1 988; 9 week study in rats.
Supplemental Data


rodent- mouse; SKEZAP Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. (Nippon Shokuhin Eisei
Gakkai c/o Shokuhin Eisei Senta, 2-6-1 Jingumae, Shibuya-ku, Tokyo 150, Japan) V.1- 1960-
Volume(issue)/page/year27,553,1986
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



21.9

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on parent Sodium

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium hypochlorite
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1020 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



989



100



0.907



1,541



16.4



160



498
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NIRS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 0.14
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
mg/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes




For parent sodium


National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Bleach; disinfectant; medication (HSDB)
Value





293,000

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Sodium methyldithiocarbamate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1021 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium methyldithiocarbamate
5951
137428
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











20.2



50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1967



1965
Critical Effect











Blood - normocytic anemia, Blood - pigmented or
nucleated red blood cells, Blood - leukopenia



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „ ,
9 10 L"L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issueXpage/year 32(2),1 1 ,1967; 30 week rabbit study
Supplemental Data


rodent- mouse; RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz
Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year 10,97,1965
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y

47.1

Y/N
Y/N

W/L
W/L






Developmental



CACART
CACART
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium methyldithiocarbamate
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1022 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies

Amount
Released
60,023,092
40
10,500

OPP Estimated Environmental Concentration

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
20
1
2



Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997
2004
2004

Surface water chronic: 0 ug/L

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes






Notes
Ground water chronic: 0 ug/L

Cancer:







Soil fumigant (HSDB)
Value


-2.62


722,000
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (HSDB)







-------
Sodium sulfide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1023 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium sulfide
11113
1313822
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















205
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1986
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude
8 10
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V/O Mezhdunarodnaya Kniga, 1 1 3095 Moscow, USSR) V.1 -36, 1957-1992. For publisher
information, see MTPEEI Volume(issue);page/year 30(8),30,1 986, rodent-mouse
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Sodium sulfide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1024 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Metal precipitation; chemical reagent; medication (HSDB)
Value





186,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (HSDB)







-------
Sodium vanadate
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1025 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sodium vanadate
23292
13718268
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.001







0.616



74.6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1986



1984
Critical Effect



Kidney- Impaired function







Gastrointestinal - ma absorption, Kidney, Ureter, Bladder -
changes in bladder weight, Nutritional and Gross
Metabolic - changes n calcium



Behavioral - ataxia, Lungs, Thorax, or Respiration -
dyspnea, Gastrointestinal - hypermotility, diarrhea
Prevalence Magnitude
5
ncomplete data for scoring HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1987, NOAEL, rat, UF=1,000
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 6-week oral study in rat; BECTA6 Bulletin of Environmental
Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year 37,899,1986
Supplemental Data


rodent- mouse; TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(ssue)/page/year 23,227,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sodium vanadate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1026 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1986
2002






Maximum
value of
Detects
Year
1997


Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial chemica
Value







Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Sorbitol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1027 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sorbitol
2145
50704
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value








833


1,167



15,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1999



1974
Critical Effect











Gastrointestinal - other changes



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
7 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, FGTOD7 Food and Chemical Toxicology. (Pergamon
Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year 37,233,1999, mammal- human study
Supplemental Data


FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued.
Volume(issue)/page/year 53A, 498,1 974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2,723

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Sorbitol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1028 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Food and pharmaceutical additive (HSDB)
Value

2
-2.2

7.30E-13
2,200,000
27
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (HSDB)







-------
Spinosyn A
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1029 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Spinosyn A
70751
131929607
Attribute Scores
Potency Severity
5 6
Prevalence Magnitude
9 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value





0.02










Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date





2001










Critical Effect





Vacuolation of the thyroid gland epithelial cells,
inflammation in the thyroid, lung, and larynx; bone-
marrow hyperplasia and dilatation of liver sinusoids










3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/SWC EEC: 1,522
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake, Acute RfD unnecessary
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data

Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Spinosyn A
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1030 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data


# Sam pies

Amount
Released
117,315



OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
21





Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997



Surface water chronic: 0.092 ug/L

Non-cancer: 1,522
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes




Notes
Ground water chronic

Cancer:







nsecticide (HSDB)
Value


2.8


89.4

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Stearic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1031 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Stearic acid
2305
57114
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











1,490




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1995




Critical Effect











Related to Chronic Data - death




Prevalence Magnitude .,, „
8 3 NL!'L!
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, JACTDZ Journal of the American College of Toxicology.
(Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-15, 1982-1996. Discontinued.
Volume(issue)/page/year 14,196,1995, 30 week rodent-rat study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3,478

Y/N
Y/N

M8/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Stearic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1032 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>500M-1B
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; food and pharmaceutical additive (HSDB)
Value

720,000
8.23

4.80E-07
0.568
4
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Sulfurous acid
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1033 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulfurous acid
19341
7782992
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1906




Critical Effect











Gastrointestinal - hypermotility, diarrhea,
Gastrointestinal - nausea or vomiting, Gastrointestinal •
other changes




Prevalence Magnitude
5
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level, AEXPBL Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see
NSAPCC. Volume(issue)/page/year 54,421,1906, human study
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.17

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Sulfurous acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1034 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies

Amount
Released



# PWSs/Sites
sampled


#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


% Samples with
detects

Number of
States



% PWSs/Sites
with detects


Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M

Units
Ibs/yr
Ibs/yr
Year
1994
2002




Maximum
value of
Detects

Year
1997


Maximum
value of
Detects


Median value of
Detects


90% of
Detects


99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Reaction product of SO2 and H2O
Value







Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Sulfuryl fluoride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1035 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulfuryl fluoride
13814
2699798
Attribute Scores
Potency Severity
6 6
Prevalence Magnitude
2 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.003












100


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date













1988


Critical Effect
Vacuolization of the white matter in the brain in female
rabbits















3-model Categorical Prediction
NL7-L?
HRL Ratio(s)
No water data
Notes
Reference Dose, 1/006
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Zenz, C. Occupational Medicine- Principles and Practical Applications. 2nd ed. St. Louis, MO: Mosby-
Yearbook, Inc, 1988., p. 684, rat and guinea pig study


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



21

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sulfuryl fluoride
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1036 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
142,720
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
2
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





nsecticide/fumigant; chemical intermediate (HSDB)
Value





750

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Sulprofos
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1037 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Sulprofos
32748
35400432
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











0.6



65
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987



1977
Critical Effect











Blood - normocytic anemia, Blood - changes in serum
composition (e.g. TP, bilirubin, cho esterol),
Biochemical - Enzyme inhibition, induction, or change
in blood or tissue levels - true cholinesterase



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude , „
7 6 L
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Otawerved Adverse Effect Level, NNQADV Nippon Noyaku Gakkaishi. Journal of the
Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku,
Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year 12,775,1987, 13 week rodent- rat study
Supplemental Data


rodent- rat; 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson
Publications, 1976/77 revision Volume(issue)/page/year 1,205,1977
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1.4

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Sulprofos
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
     August 2009
Page 1038 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies
Amount
Released
308,039


# PWSs/Sites/
Samples
283
669




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


0



% Samples with
detects
Number of
States
8


% PWSs/Sites/
Samples with
detects


0



Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects


Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects
Year
1997


Maximum
value of
Detects


Not Detected



Median value of
Detects


90% of
Detects


99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


Not Detected
99% of
Detects


Not Detected
Units for Mag
data



Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 9002(GC/MS)

Cancer:







Cancelled insecticide (HSDB)
Value
38
12,000-13,500
5.48

8.60E-07
0.31
7
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Tartrazine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1039 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tartrazine
12444
1934210
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












773
7.5


12,750
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d

mg/kg
mg/kg
mg/kg
Date












2006



1966
Critical Effect












Neurobehavioral effects



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
5 8 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data, Tanaka Food chem Toxicol 44:179-87 2006
Supplemental Data; Maximum Recommended Da ly Dose (MRDD)


rodent- mouse; FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77.
Discontinued. Volume(issue)/page/year 386,88,1966
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

1,804

Y/N
Y/N

W/L
W/L






teratogen list




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tartrazine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1040 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies

Amount
Released



# PWSs/Sites
sampled




#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects

Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
n sanitizing solut
Value





300,000
50
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects

Year
1997


Maximum
value of
Detects




Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ons (food industry); in dyes (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (HSDB)







-------
Tebuthiuron
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1041 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tebuthiuron
32336
34014181
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.07
0.07
0.07
0.07






7
96




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1992




Critical Effect
Reduced body weight gain in F1 females
Depressed body wieght gain in F1 males

Depressed body weight gain in females







Gastrointestinal - changes in structure or function of
endocrine pancreas, Kidney, Ureter, Bladder - changes in
bladder weight




Prevalence Magnitude .,, .,, „
10 3 NL'NLi
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 7,424
Notes
Reference Dose
Reference Dose, Elanco Products, 1981, Basis NOEL = 7 mg/kg-d, rat, UF = 100
Reference Dose
Reference Dose, Elanco Products, 1981, NOEL/LEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Toshima-ku, Tokyo 170, Japan) V.1- 1976- Vo ume(issue)/page/year 17,335,1992
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification




D

mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer


2
490

Y/N
Y/N
mg/L
W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tebuthiuron
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
     August 2009
Page 1042 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP
POP
PPMP
PPMP

CAL DHS

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,097

# Sam pies
Amount
Released
115,712
0
5
# PWSs/Sites/
Samples
154
336


# PWSs/Sites/
Samples
66

799

#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
3
19
64
42
#with Detects


11.26

% Samples with
detects
Number of
States
2
0
1
% PWSs/Sites/
Sam pies with
detects
1.9
5.7
28.1
18.7
% PWSs/Sites/
Sam pies with
detects
0

0.001

Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects
16.3
1


Minimum value of
Detects


Non-cancer: 7,424
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



17.3

Maximum
value of
Detects
Year
1997
2004
2004
Maximum
value of
Detects
16.3
14
0.032
0.077
Maximum
value of
Detects


0.013

Median value of
Detects
0.066

90% of
Detects
0.546

99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects




Median value of
Detects

95% of
Detects


0.019
0.077
90% of
Detects

Units for Mag
data
ng/L
ng/L
ug/L
ug/L
Units for Mag
data
ug/L
Notes
Pesticide Data Program (USDA) 2001
Pesticide Data Program (USDA) 2002
Pesticide Pilot Monitoring Program (USGS/EPA) 2001(GC/MS)
Pesticide Pilot Monitoring Program (USGS/EPA) 9060(HPLC/MS)
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

Cancer:







Herbicide (HSDB)
Value
38
22.8
1.79

1.20E-10
2,500
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Terbufos-O-analogue sulfone
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1043 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Terbufos-O-analogue sulfone
76778
56070156
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 3
Scores based on parent
Prevalence Magnitude ,,,
1 1 NL
Scores based on parent HRL Ratio(s)
HEALTH EFFECTS DATA1 See Terbufos and Terbufos sulfone Parent Terbufos and Terbufos sulfone on CCL for parent terbufos)
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.00005















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Plasma ChE inhibition















Notes
Reference Dose - FOR PARENT TERBUFOS
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.35

Y/N
Y/N

ug/L
M/L












Drinking Water Equivalent Level
Based on data for parent terbufos

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Re ative Source Contribut on of 20%. For carcinogens, the concentration at the 10 "B cancer risk was used.

-------
    Terbufos-O-analogue sulfone
    CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                             EPA-OGWDW
     August 2009
Page 1044 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Finished Water Occurrence Data FOR TERBUFOS - PARENT
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
300


0


0


Minimum value of
Detects
Maximum value
of Detects
Median value of
Detects
90% of
Detects
99% of Detects

Not Detected


Not Detected


Not Detected


Not Detected


Not Detected


Ambient Water Occurrence Data FOR TERBUFOS - PARENT
N AWQA ambient water
MREC ambient surface water
MREC ambient ground water
MREC ambient surface water
MREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
PPMP finished water
PPMP ambient water

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
r,72, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118

# Samples

Amount
Released



# PWSs/Sites/
Samples


22

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2
0

0.31

% Sam pies with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
0.9
0

0.0021

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects


Non-cancer: 1.67
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



0.56

Maximum value
of Detects

Year
1997
2004
2004
Maximum value
of Detects
0.016

0.017

Median value of
Detects

0.21

90% of
Detects

0.56

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects


99% of
Detects

Units for Mag
data

Notes
Pesticide Pilot Mentoring Program (USGS/EPA)
Pesticide Pilot Mentoring Program (USGS/EPA)

Cancer:



NAWQA data and HRL for Parent Terbufos



Analogue and degradate of the pesticide terbufos
Value
38 days





14
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA= Biodegrades slow with acclimaton (PBT)







-------
Terephthalic acid
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1045 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Terephthalic acid
4091
100210
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHERfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



1







143



3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1971
Critical Effect



Bladder- Hyperplasia







Brain and Coverings - changes in brain weight, Cardiac -
changes in heart weight, Kidney, Ureter, Bladder -
changes in bladder weight



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
10 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose, U.S. EPA, 1986, NOEL, rat, UF = 100
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; 2-year oral study in rat; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/yearOTS0543783
Supplemental Data


rodent- mouse; KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650)
Volume(issue)/page/year 21 MAY1 971
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7,000

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Terephthalic acid
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1046 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1H, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



# Sam pies
Amount
Released



# PWSs/Sites
sampled




#with Detects
Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects




% Samples with
detects
Number of
States



% PWSs/Sites
with detects




Minimum value of
Detects
Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002






Maximum
value of
Detects
Year
1997


Maximum
value of
Detects




Median value of
Detects



90% of
Detects



99% of Detects
Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in poultry feeds (HSDB)
Value

71.6
2

3.89E-13
15

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
tert-Butanol
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1047 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butanol
2670
75650
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










90
107




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1995




Critical Effect










Decreased body weight males; increased relative and
absolute and relative kidney weights Cancer some
evidence in male rats and female mice, equivocal
evidence in male mice and no evidence in female rat
Liver - other changes, Nutritional and Gross Metabolic -
weight loss or decreased weight gain




Prevalence Magnitude , „
10 9 L
HRL Ratio(s)
NCHRL/CALDHS90%:21.1
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, NTP TR436
Lowest Observed Adverse Effect Level; 10-week oral study in rat; TOLED5 Toxicology Letters. (Elsevier
Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year
80,97,1995




Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

630

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   tert-Butanol
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                            EPA-OGWDW
     August 2009
Page 1048 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/CAL DHS 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

12,324
1,548,617
# PWSs/Sites/
Samples
7,600



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
86



% Samples with
detects

Number of
States

7
31
% PWSs/Sites/
Samples with
detects
1.13



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
2

Non-cancer: 21.1
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
93



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
3.95

90% of
Detects
29.9

Units for Mag
data
ug/L

Cancer:



Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx





Former pesticide; gasoline additive; in PPCPs (HSDB)
Value

37
0.35

9.05E-06
1,000,000
44
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS/BST






Notes
BS = Biodegrades slow (BIODEG); BST = Biodegrades sometimes/recalcitrant (BIODEG)







-------
tert-Butyl hydroperoxide
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1049 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butyl hydroperoxide
2693
75912
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















320
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1979
Critical Effect















Behavioral - irritability, Gastrointestinal - alteration in
gastric secretion, Blood - hemorrhage
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New
ndustrial Chemical Substances. For English translation, see TNICS. (Izdatel'stvo Meditsina,
Moscow, USSR) No.1- 1961- Volume(issue)/page/year 15,90,1979, rodent-mouse
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   tert-Butyl hydroperoxide
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1050 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies


Amount
Released



# PWSs/Sites
sampled



#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects


Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects


Year
1997


Maximum
value of
Detects



Median value of
Detects




90% of
Detects




99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; chemical intermediate (HSDB)
Value
1 5 days
97
0.94

1.60E-05

42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
tert-Butylamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1051 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butylamine
2669
75649
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















44
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral - food intake (animal), Lungs, Thorax, or
Respiration - pulmonary emboli, Liver - other changes
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information. Volume(issue)/page/year OTS0534846, rodent-rat
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   tert-Butylamine
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1052 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate for rubber accelerators, insect
Value
1 5 days
40
0.4


1,000,000
47
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS











Maximum
value of
Detects

Year
1997


Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





cides, fungicides, dyestuffs, Pharmaceuticals and oil additives (HSDB)
Notes
BS = Biodegrades s ow (PBT)







-------
tert-Butyl benzene
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1053 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
tert-Butylbenzene
3932
98066
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











4.42



3,045
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1990




Critical Effect











Behavioral -alteration of classical conditioning




Prevalence Magnitude ,,, „
3 6 NL'
HRL Ratio(s)
NC HRL/NCOD R1 90%: 1.03
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; VCVGH "Vredniechemichescie veshestva,
galogenproisvodnie uglevodorodov". (Hazardous substances Galogenated hydrocarbons)
Sandman A. L. etal.,Chimia, 1990. Volume(issue)/page/year -,179, 1990; 24 week oral study in rats
Supplemental Data


rat study
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



10.3

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   tert-Butyl benzene
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
     August 2009
Page 1054 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

12,353
22,973


24
25


0.19
0.11


0.02
0.10


10
77.5


0.8
0.5


10
5


10
77.5

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (HRL/NCOD R1 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
4,309

# Sam pies

Amount
Released



# PWSs/Sites/
Samples
11,885

10

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
2

0.232

% Samples with
detects

Number of
States



% PWSs/Sites/
Samples with
detects
0.02

0.009

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects
0.62

Non-cancer: 1.03
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.1

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects
0.9

0.06

Median value of
Detects

0.11

90% of
Detects

1.1

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
0.76

90% of
Detects
0.872

Units for Mag
data
ug/L

Cancer:



Notes






Solvent; in organ c synthesis (HSDB)
Value
38 days
1,181
4.11

0.0132
29.5
14
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Tetraethyl lead
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1055 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetraethyl lead
2781
78002
Attribute Scores 3-model Categorical Prediction
Potency Severity
10 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0000001









0.06




Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1985









1983




Critical Effect

Histopathology of liver & thym us









Endocrine - other changes




Prevalence Magnitude
5 7 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose; Basis = LOAEL 0.0012 mg/kg-day, rat, UF = 10,000 (Schepers, 1364)
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 6W-C; JANSY Journal of the autonomic nervous
system (Amsterdam, Elsevier/North Holland Biomedical Press) V.1-81 1979-2000.
Volume(issue)/page/year8,287,1983
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

0.0007

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tetraethyl lead
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1056 of 1124
OCCURRENCE DATA1

Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects




































# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former anti-knock agent in gasol ne; chemical intermediate (HSDB)
Value

758
4.15

0.568
0.29

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DS






Notes
DS = Degrades slow (HSDB)







-------
Tetrafluoroethene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1057 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrafluoroethene
5138
116143
Attribute Scores
Potency Severity

Prevalence Magnitude
7 7
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction

HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1999











Vol. 19, Suppl 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

W/L
W/L










CACART; IARC; Clear evidence of carcinogenicity in male and female rats and mice (NTP).

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Tetrafluoroethene
    CCL 3 Contaminant Information Sheet
                                                                                                EPA-OGWDW
     August 2009
Page 1058 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Polymer intermec
Value

110


0.63
159
44
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate; in propellants (HSDB); gas
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (HSDB)







-------
Tetrahydrofuran
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1059 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrahydrofuran
4813
109999
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 7
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value







0.01


481
38.2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date







2000



1967




Critical Effect










Systemic parental and developmental toxicity.
Blood - change in clotting factors, Blood - changes in
eukocyte (WBC) count, Nutritional and Gross Metabolic -
weight loss or decreased weight gain




Prevalence Magnitude , „
96 L
HRL Ratio(s)
NC HRL/NAWQA AW 90% : 375
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake; Oral study
Supplemental Data
No Observed Effect Level
Supplemental Data; (Hellwig, et al. Food and Chemical Toxicology 40 (2002) 1515-1523)
Lowest Observed Adverse Effect Level; oral study in rat 17W-I; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 32(2), 99,1 967
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



3,366

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tetrahydrofuran
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1060 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NAWQA AW 90% )
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
2,601

# Sam pies

Amount
Released



# PWSs/Sites
sampled

93

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

3.58

% Samples with
detects

Number of
States



% PWSs/Sites
with detects

0.07

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 375
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



1,430

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

0.75

Median value of
Detects

8.98

90% of
Detects

1,146

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Solvent (HSDB)
Value
15 days
18-23
0.46

7.10E-05
1,000,000
48
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Tetramethylammonium chloride
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1061 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetramethylammonium chloride
2662
75570
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















50
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect















Behavioral -somnoence (general depressed activity),
Behavioral - convulsions or effect on seizure
threshold, Skin and Appendages - hair
Prevalence Magnitude , „
67 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(NTIS National Technical Information Service. (Springfield, VA 22161) Formerly U.S.
Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year OTS0536975)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tetramethylammonium chloride
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1062 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Drug / Therapeutic Agent (NLM/NIH/ChemlDPIus)
Value
1 5 days

-4.18



39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Tetramethylammonium hydroxide
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1063 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetramethylammonium hydroxide
2664
75592
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









5




34

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Decreased relative organ weight






Prevalence Magnitude ,,, „
6 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level; NOEL Type - Repeat Dose
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



35

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tetramethylammonium hydroxide
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1064 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n semiconductor manufacturing (NLM/NIH/Haz-map)
Value
1 5 days

-2.47



39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Tetrasodium EDTA
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1065 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tetrasodium EDTA
2459
64028
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










250


2,000


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










1966


2004


Critical Effect










No observed effects





Prevalence Magnitude
8 8 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data, Oser et al, 1 966
Lowest Observed Adverse Effect Level
Supplemental Data
European Chemicals Bureau; IUCLID Dataset, Tetrasodium ethyleneadiaminetetraacaetate (64-02-8)
(2000 CD-ROM edition). Available from the database query page: http://ecb.jrc.it/esis/esis.php as of
February 18, 2004.


Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



1,750

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tetrasodium EDTA
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1066 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chelating agent (HSDB)
Value
60 days




500,000
50
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
Texanol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1067 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Texanol
28538
25265774
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















3,200
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1981
Critical Effect















Details of toxic effects not reported otherthan lethal
dose value
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(KODAK Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/pagefyear
M-158E.1981)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 10 "6 cancer risk was used.

-------
   Texanol
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
     August 2009
Page 1068 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E, Half life
KOC, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
XIOOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





n latex paints; chemical intermediate (OECD/SIDS)
Value
1 5 days





20
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Thifensulfuron
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1069 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thifensulfuron
66172
79277671
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
Scores based on parent
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.02















Units
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
Decreased body weight and body weight gain















Prevalence Magnitude , „
10 7 L
Scores based on parent HRL Ratio(s)
No water data
Notes
Reference Dose (for thifensulfuron-m ethyl)
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



140

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level
Based on RfD for thifensulfuron-methyl.

1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thifensulfuron
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1070 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
105,145


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
37


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes
Data for thifensulfuron-methyl


Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Derivative of the pesticide thifensulfuron-methyl (HSDB)
Value
60 days





38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Thiocarbazide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1071 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiocarbazide
12972
2231574
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















6
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1994
Critical Effect















Behavioral - somno ence (general depressed activity),
Behavioral - convulsions or effect on seizure
threshold, Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude , „
57 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(MTPEEI Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology.
(Mezhdunarodnaya Kniga, ul.B. Yakimanka, 39 1 17049 Moscow, Russia) No.1- 1993-
Volume(issue)/page/year(2),43,1994)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Thiocarbazide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1072 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1E( Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Veterinary medic ne; microscopy reagent (HSDB)
Value
15 days

-2.04


5,500
39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Thiophenol
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1073 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiophenol
4734
108985
Attribute Scores 3-model Categorical Prediction
Potency Severity
8 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.00001







0.01



46.2
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1994



1958
Critical Effect



Centrilobular eosinophilic changes







Behavioral - changes in motor activity (specific assay),
Blood - changes in leukocyte (WBC) count, Biochemical -
Enzyme inhibition, induction, or change in blood or tissue
evels - transaminases



Behavioral - somnolence (general depressed activity),
Behavioral - coma, Lungs, Thorax, or Respiration -
respiratory depression
Prevalence Magnitude ,,, „
1 7 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 1,7,1994
Supplemental Data


AIHAAP American Industrial Hyg ene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH
44311) V.19- 1958- Volume(issue)/page/year 19,171,1958
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



0.07

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thiophenol
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1074 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for pesticides, Pharmaceuticals and dyes; mosquito larvicide (HSDB)
Value
1 5 days
268
2.52

0.000335
835

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Thiram
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1075 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thiram
5945
137268
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.015
0.005

0.005

0.01





0.005




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1987



1992





1993




Critical Effect
Changes in hematology, clinical chemistry, incidences
of bile duct hyperplasia, & reduction in mean body
weight gain
Neurotoxicity

Neurotoxicity







Cardiac - arrhythmias (including changes in conduction),
Cardiac - other changes




Prevalence Magnitude
95 Li
HRL Ratio(s)
NC HRL/SWC EEC: 24.4
Notes
Reference Dose
Reference Dose; Basis = NOEL 5 mg/kg-day, rats, oral, UF = 1000 (DuPont, 1954)
Reference Dose
Reference Dose; Basis = NOEL/LEL, rats, oral, lowconf, UF = 100, MF = 1 (DuPont, 1954)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in pig; CUTOEX Current Toxicology. (Nova Science
Publishers, Inc., 6080 Jericho Turnpike, Suite 207, Commack, NY 11725) V.1 1993-
Volume(issue)/page/year 1,221,1993.
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1



















Vol53; 1991
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

105

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thiram
   CCL 3 Contaminant Information Sheet

OCCURRENCE DATA1
                                                                                           EPA-OGWDW
     August 2009
Page 1076 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water

NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total



# Sam pies

Amount
Released
179,809
34
102,508



#with Detects

Units
Ibsfyr
Ibs/yr
Ibs/yr



% Samples with
detects

Number of
States
21
5
21



Minimum value of
Detects

Units
States
States
States



Maximum
value of
Detects

Year
1997
2004
2004



Median value of
Detects




90% of
Detects




99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Supplemental Water Data
OPP Estimated Environmental Concentration

HRL Ratios (HRL/SWC EEC)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
Surface water chronic: 4.3 ug/L

Non-cancer: 24.4
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002



Ground water chronic: 0.84 ug/L

Cancer:







Pesticide; rubber accelerator; antiseptic (HSDB)
Value
1 5 days
10
1.73

3.03E-07
835

Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slow (PBT)







-------
Thorium-232
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1077 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Thorium-232
18853
7440291
Attribute Scores 3-model Categorical Prediction
Potency Severity

Prevalence Magnitude
5 8
No further evaluation for CCL - regulated under Radionuclides Rule. HRL Ratio(s)
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

1.01E-10




mg/L
risk/pCi
(mg/kg-d)-1
(mg/kg-d)"1















pCi = picoCuries




Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

W/L
W/L










RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Thorium-232
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1078 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water



989



5



0.506







61.7



6



39



59
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Nuclear reactors; welding; ceramics (HSDB)
Value



150,000



Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code







Notes








-------
Tralomethrin
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1079 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tralomethrin
42610
66841256
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0075

0.0075







10



99
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1991
Critical Effect

Decreased body weight gain; increased water
consumption









Behavioral - tremor, Behavioral - ataxia, Gastrointestinal -
nausea or vomiting



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude
8 3 NLi
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose; Basis: NOEL of 0.75 mglkgWay in oral Rat study (Roussel UCLAF, 1 984); UF =
100
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in dog 13W-C; NTIS National Technical Information
Service. (Springfield, VA22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year OTS05451 97
Supplemental Data


Rat; PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath
CR47QG, UK) V.1- 1968- Vo ume(issue)/page/year 9,829,1991
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



52.5

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Tralomethrin
   CCL 3 Contaminant Information Sheet
OCCURRENCE DATA1
                                                                                            EPA-OGWDW
     August 2009
Page 1080 of 1124

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
























Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
POP

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

# Sam pies


Amount
Released
23,767


# PWSs/Sites/
Samples
115


#with Detects


Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
0


% Samples with
detects


Number of
States
15


% PWSs/Sites/
Samples with
detects
0


Minimum value of
Detects


Units
States
States
States
Minimum value of
Detects
Not Detected

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002




Maximum
value of
Detects


Year
1997
2004
2004
Maximum
value of
Detects
Not Detected


Median value of
Detects



90% of
Detects



99% of Detects


Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes






National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects
Not Detected

99% of
Detects
Not Detected

Units for Mag
data
ug/L

Cancer:



Notes
Pesticide Data Program (USDA)





Pesticide; medication (HSDB)
Value
180 days
263,000
7.56

3.94E-10
0.08
1
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Tribromoacetic acid (TBAA)
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1081 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Tribromoacetic acid (TBAA)
2695
75967
Attribute Scores 3-model Categorical Prediction
Potency Severity

Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification





mg/L
(mg/kg-d)"1
(mg/kg-d)-1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N
mg/L
W/L
W/L










Prevalence Magnitude
9 8
HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tribromoacetic acid (TBAA)
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1082 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR finished water




# PWSs/Sites
sampled
2,587




#with Detects
89




% PWSs/Sites
with detects
3.4




Mean value of
Detects
5.77




Maximum
value of
Detects
19




Median value of
Detects
5




90% of
Detects





99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data
CAL DHS

HRL Ratios (no HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T1n, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler



Amount
Released


# PWSs/Sites/
Samples
40




Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects
10




Number of
States


% PWSs/Sites/
Samples with
detects
25




Units
States
States
States
Minimum value of
Detects (ug/L)
1

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002






Year


Maximum
value of
Detects (ug/L)
15










Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes









National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes


Median value of
Detects (ug/L)
4

90% of
Detects (ug/L)
7.52

Units for Mag
data
ug/L
Notes
Drinking water monitoring;
http://www.cdph.ca.gov/certlic/drinkingwater/Pages/Chemicalcontaminan
ts.aspx

Cancer:







Disinfection By-Product
Value
15 days
5.3
1.71

3.34E-09
200,000
26
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades slowly







-------
Tributyltin chloride
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
     August 2009
Page 1083 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tributyltin chloride
11595
1461229
Attribute Scores 3-model Categorical Prediction
Potency Severity
7 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0003









15



0.03
Units
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1985



1986
Critical Effect

Based on IRIS RfD for TBT oxide, converted to
TBTchloride. Immunosuppression









Endocrine - other changes, Endocrine - changes in spleen
weight, Endocrine - changes in thymus weight



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
5 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 2W-C; TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/paqe/year81,274,1985
Supplemental Data


Rat; 85JCAE "Prehled PrumysloveToxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986 Volume(issue)/page/year -,1250,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



2.1

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tributyltin chloride
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1084 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former pesticide; chemical intermediate (HSDB)
Value
6 days-35
weeks
90,800

60,000



Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (HSDB)







-------
Trichloroacetonitrile
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
     August 2009
Page 1085 of 1124
Contaminant:
Substance Key:
Contaminant ID (CASRN):
Trichloroacetonitrile
7769
545062
Attribute Scores
Potency Severity

Prevalence Magnitude
8 6
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect
















Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Carcinogen classification
ARC Carcinogen Classification




3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1












Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y



Y/N
Y/N
mg/L
W/L
W/L






Teratogen



3-model Categorical Prediction

HRL Ratio(s)
No HRL
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data











UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Trichloroacetonitrile
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1086 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water

DBP ICR finished water




# PWSs/Sites
sampled
11,127




#with Detects
192




% PWSs/Sites
with detects
1.7




Mean value of
Detects
4.23




Maximum
value of
Detects
41.54




Median value of
Detects
0.8




90% of
Detects





99% of Detects

Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (no HRL)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler




Amount
Released



# Sam pies





Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects





Number of
States



% Samples w/
Detects





Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500k
10K-500k
Units
Ibs/yr
Ibs/yr
Year
1998
2002







Year



Maximum
value of
Detects













Units for Mag
data

ug/L
ug/L
ug/L

Units for Mag
data
ug/L

ug/L
ug/L
ug/L
ug/L
ug/L
Notes





Notes



National Reconnaissance
National Reconnaissance
National Aggregate
National Aggregate
Notes



Median value of
Detects

95% of
Detects

Units for Mag
data

Cancer:



Notes





Disinfection By-Product
Value
60 days
330
2.09

1.34E-06
715
27
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant







-------
Triethanolamine
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1087 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triethanolamine
4260
102716
Attribute Scores
Potency Severity
5
Prevalence Magnitude
8 5
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value












10



Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction

HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data; Maximum Recommended Da ly Dose (MRDD); Incomplete data for attribute scoring



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







2000











Vol. 77
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



23.33

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Triethanolamine
   CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
     August 2009
Page 1088 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Cancelled pesticide; chemical intermediate; in detergents; chelating agent (HSDB)
Value

7
-1

7.10E-13
1,000,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Triethylene glycol
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1089 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triethylene glyco
5015
112276
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value











3.57



7,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1987




Critical Effect











Liver -liver function tests impaired, Kidney, Ureter,
Bladder - other changes, Biochemical - Enzyme
inhibition, induction, or change in blood or tissue
levels -transaminases



Liver - other changes, Kidney, Ureter, Bladder - other
changes
Prevalence Magnitude , „
85 L'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; (GISAAA Gigiena i Sanitariya. For English translation, see
HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
VolumefissueXpagefyear 52(1 2),77,1987)
Supplemental Data


Guinea pig; VCVGK "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie
soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al.,
Chimia, 1994. Volume(issue)/page/year -,146,1984
Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
IARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
Is contaminant on list of carcinogens?
Is the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



8.33

Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Triethylene glycol
    CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1090 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log KOW, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


^Samples

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>1QOM-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ndustrial solvent; plasticizer; medication (HSDB)
Value

10


3.10E-11

39
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIO DEC)







-------
Trifluralin
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
     August 2009
Page 1091 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trifluralin
11820
1582098
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
0.024
0.0075
0.0075
0.0075






0.75
25




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1991




Critical Effect
Reduced body weight, decreased RBC & hemoglobin
evels, increased thrombocyte, methemoglobin,
cholesterol & triglyceride levels & increased liver
weight. Q1* 0.0058 (mg/kg-day)-1 . Group C. See CAR


ncreased liver weight, increase in methemoglobin







Liver - changes in liver weight




Prevalence Magnitude .,, .,, „
g 2 NL-NL;
HRL Ratio(s)
NC HRL/NAWQA 90%: 6,222
CARHRL/NAWQA90%:5
Notes
Reference Dose
Reference Dose; Basis = NOEL 0.75 mg/kg/day, dog, oral, UF = 100 (Hoechst Aktiengesellschaft, 1984a)
Reference Dose
Reference Dose; Basis = NOEL/LEL, dog, MF = 1 (Hoechst Aktiengesellchaft, 1984)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in dog 3Y-I; NNGADV Nippon Noyaku Gakkaishi.
Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1 -43-1 1 , Komagome,
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.5
0.0077

0.0058
C
3
mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1





2004






Kidney, bladder, thyroid




OPP
Emmerson etal., 1980

Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
CADW
Y

0.3
168
5
0.045
Y/N
Y/N
mg/L
W/L
W/L
mg/L












RAISHE

Drinking Water Equivalent Level


Canadian Drink ng Water Maximum Allowable Concentration
1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
   Trifluralin
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1092 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Units for Mag
data

ug/L
ug/L
ug/L
ug/L
Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NAWQA 90%)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
7,118

# Sam pies

Amount
Released
22,263,693
0
9,341
# PWSs/Sites
sampled

380

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

5.34

% Samples with
detects

Number of
States
46
0
12
% PWSs/Sites
with detects

0.0005

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 6,222
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002



1.74

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

0.006

Median value of
Detects

0.027

90% of
Detects

0.15

99% of Detects

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 185



Notes





Herbicide (HSDB)
Value
180 days
9,682
5.34

0.000103
0.184
3
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Trimellitic anhydride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1093 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimellitic anhydride
7816
552307
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 5
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value






0.75








1,900
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1974
Critical Effect















Lungs, Thorax, or Respiration - dyspnea
Prevalence Magnitude ,,, _
8 3 NL'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information s available; hence LD 50 used for Potency/Severity
scoring.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Mouse; GTPZAB Gigiena Truda i Professiona 'nye Zabolevaniya. Labor Hygiene and Occupational
Diseases. (V«D Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher
information, see MTPEEI Volume(issue)/page/year 18(7),57,1974
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

M/L
M/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For care nogens, the concentration at the 1 0 "6 cancer risk was used.

-------
    Trimellitic anhydride
    CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1094 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


^Samples

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>100M-500M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Preparation of resins, adhesives, polymers, dyes; chem cal intermediate (HSDB)
Value






23
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
DF






Notes
DF = Degrades fast (HSDB)







-------
Trimethyl phosphate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1095 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethyl phosphate
7393
512561
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 8
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









40

70.2




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1997




Critical Effect











Peripheral Nerve and Sensation - sensory syndrome
diagnostic of central lesion, Behaviora - muscle
weakness, Blood - pigmented or nucleated red blood cells




Prevalence Magnitude
1 8 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level; Changes in thymus and kidney weight; hematological effects;kidney lesions;
nephropathy; decreased copulation rate, decreased fertility index and number of implantation sites;
ntrauterine mortality of embryos ncreased.
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 2.5Y-C; FAATDF Fundamental and Applied
Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher
nformation, see TOSCF2 Volume(issue)/page/year 40,75,1997
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.037




mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y
Y


0.946
Y/N
Y/N

W/L
W/L






Teratogen



CACART; RAISHE
CACART; UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Trimethyl phosphate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1096 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
10K-500K
10K-500K
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Gasoline additive; antioxidant (HSDB)
Value

7.644
-0.65

7.19E-09
500,000

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (BIODEG)







-------
Trimethylamine
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1097 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethylamine
2657
75503
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









40




397

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Intestinal lesions. Inflammation, ulceration, and
hyperplasia of squamous epithelium; edema of
submucosa in Gltract.






Prevalence Magnitude
7 7 Li
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 10"*
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



280

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Trimethylamine
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1098 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Organic synthesis; corrosion inhibitor; fungicide (HSDB)
Value

29
0.16


890,000
52
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Trimethylolpropane
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1099 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trimethylolpropane
2780
77996
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value






0.05


800





13,700
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1967
Critical Effect









ncreased relative organ weight





Behavioral - somnolence (general depressed activity),
Lungs, Thorax, or Respiration - dyspnea, Lungs, Thorax,
or Respiration - respiratory depression
Prevalence Magnitude
7 7 NLi
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake; No Severity information is available; hence NOEL used for Potency/Severity
scoring.
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Mouse; HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-
71. Discontinued. Volume(issue)/page/year 32(5), 288, 1967
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



5,600

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Trimethylolpropane
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1100 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>50M-100M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate for polymers (HSDB)
Value





1,000,000
40
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (BIODEG)







-------
Trinitrotoluene
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
     August 2009
Page 1101 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Trinitrotoluene
5251
118967
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.0005
0.0005
0.0005
0.0005






0.12




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988
1995

1995






1982




Critical Effect

Liver effects (increased relative & absolute liver
weight, hepatocytic cloudy swelling &
hepatocytom egaly)

Liver







Liver - changes in liver weight, Endocrine - changes in
spleen weight, Blood - changes in spleen




Prevalence Magnitude ,,, „
5 3 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = LOAEL 0.5 mg/kg-d, UF = 1000, dog (U.S. DOD, 1983)
Reference Dose; Oral, Int., UF = 1000, endpoint hepatic
Reference Dose; Basis = LOAEL, MF = 1 , UF = 1 000, dog (US DOD, 1 983)
Minimal Risk Level; Int. Oral, Endpoint = hepatic, UF = 1000
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in mouse 13W-C; JTEHD6 Journal of Toxicology and
Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1-
1975/76- Volume(issue)/page/year 9,565,1982
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification
0.1
0.03


C
3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1







1996




Bladder





Oral, rat (US DOD, 1984a)
Vol. 65
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y

0.02
3.5
1
Y/N
Y/N

W/L
W/L


mg/L







EPA; RAISHE

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Trinitrotoluene
   CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1102 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Explosive; chem cal intermediate (HSDB)
Value

1,834
1.6

5.48E-07
130

Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimation (BIODEG)







-------
Triphenyl phosphite
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1103 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Triphenyl phosphite
4154
101020
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value















444
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date















1981
Critical Effect















Details of toxic effects not reported other than lethal
dose value
Prevalence Magnitude , „
6 5 L'
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


(GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1- 1936- Vo ume(issue)/page/year46(12),13,1981)
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)"1
(mg/kg-dr1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Triphenyl phosphite
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1104 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002
Chemical intermed ate; antioxidant/stabilizer; insect c
Value
38 days

6.62



2
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA











Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





de synergist (HSDB)
Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Tris(2,3-dibromopropyl) phospha
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1105 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(2,3-dibromopropyl) phosphate
5620
126727
Attribute Scores
Potency Severity
7 8
Prevalence Magnitude
1 2
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction
NL?
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve

Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification


2.3


2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)"1







1999











Vol. 20, Suppl. 7, Vol. 71 ; Cancer classifications were used for screening, but no related quantitative
cancer risk data were identified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y



0.0152
Y/N
Y/N

W/L
W/L










CACART; IARC; OEHHA

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tris(2,3-dibromopropyl) phospha
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1106 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released

0
500
# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States

0
1
% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





No longer used in the US; former flame retardant (HSDB)
Value
60 days
5,100
4.29

2.60E-05
8
8
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Tris(2-chloroethyl) phosphite
CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
     August 2009
Page 1107 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(2-chloroethyl) phosphite
6020
140089
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 9
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value













100


Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg
mg/kg
mg/kg
Date













1996


Critical Effect













Details of toxic effects not reported other than lethal
dose value


Prevalence Magnitude ,
6 8 L
HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data
Oral, rat (Lewis, R.J. Saxs Dangerous Properties of Industrial Materials. 9th ed. Volumes 1 -3. New
York, NY: Van Nostrand Reinhold, 1996., p. 2691)


Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer





Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tris(2-chloroethyl) phosphite
   CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
     August 2009
Page 1108 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Flame retardant (HSDB)
Value
60 days





42
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/reca citrant (PBT)







-------
Tris(chloroethyl) phosphate
CCL 3 Contaminant Information Sheet
                                                                                              EPA-OGWDW
     August 2009
Page 1109 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Tris(chloroethyl) phosphate
5129
115968
Attribute Scores
Potency Severity
5 8
Prevalence Magnitude
10 4
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.3












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



Brain - histological lesions. Also causes kidney tumors -
adenomas and carcinomas












3-model Categorical Prediction
L?
HRL Ratio(s)
NC HRL/NREC SW MED: 21,000
CAR HRL/NREC SW MED: 25
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification

0.014



3
mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


2,100
2.5
Y/N
Y/N

W/L
W/L










RAIS

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Tris(chloroethyl) phosphate
   CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1110 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (HRL/NREC SW MED)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler

85
# Sam pies

Amount
Released



# PWSs/Sites
sampled


19
#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects


57.6
% Samples with
detects
35
6.13
Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer: 21,000
Amount Range
>1M-10M
>1M-10M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects


0.1
Median value of
Detects
0.18
0.195


90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer: 25



Notes





Flame-retardant in plastics and urethanes (HSDB)
Value
60 days
301
1.44

2.54E-08
7,000
38
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
BST = Biodegrades sometimes/recalcitrant (PBT)







-------
Undecane
CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1111 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Undecane
10679
1120214
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value









100




2,000

Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgflsg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect









Salivation and decreased food consumption.






Prevalence Magnitude ,,,
83 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



700

Y/N
Y/N

M8/L
M8/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "B cancer risk was used.

-------
    Undecane
    CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1112 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


^Samples

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>50M-100M
>100M-500M
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Gasoline constituent; research chemical; chemical intermediate (HSDB)
Value
8,7 days

6.5

1.93
0.0044
18
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (PBT)







-------
Urea
CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1113 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Urea
2307
57136
Attribute Scores 3-model Categorical Prediction
Potency Severity
2 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value










3,600
200



8,471
Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date










2002
1977



1986
Critical Effect










Drowsiness and diuresis (nonadverse)
Behavioral - tremor, Behavioral - muse e weakness,
Gastrointestinal - alteration in gastric secretion



Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,,
10 5 NL
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data; OPP NOAEL (TRED)
Lowest Observed Adverse Effect Level; JANSAG Journal of Animal Science. (American Soc. of Animal
Science, 309 W.Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year 45,566,1977
Supplemental Data


GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year 51(6), 8,1986
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)"1
(mg/kg-d)"1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



25,200

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Urea
   CCL 3 Contaminant Information Sheet
                                                                                         EPA-OGWDW
     August 2009
Page 1114 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; in fertilizers; as medication; de-icer; formerly in pest cide formulations (HSDB)
Value

8
-2.11

1.74E-12
545,000
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BF






Notes
BF = Biodegrades fast (BIODEG)







-------
Vanadium pentoxide
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1115 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vanadium pentoxide
11141
1314621
Attribute Scores 3-model Categorical Prediction
Potency Severity
4 1
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.009

0.009







0.5




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1988









1961




Critical Effect

Decreased haircystine content. Not an adverse effect.
Decreased Potency Score by one integer

Decreased hair cystine content







Behavioral - alteration of operant conditioning




Prevalence Magnitude ,,, ,,, „
58
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = NOAEL 0.89 mg/kg-d, rat, oral, UF = 100 (Stokinger et al., 1 953 )
Reference Dose
Reference Dose; Basis = NOAEL, MF= 1, rat, UF = 100 (Stokinger et al., 1953)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat 26W-I; GISAAA Gigiena i Sanitariya. For
English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year 26(1 0), 6,1 961
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)"1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

63

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribution of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vanadium pentoxide
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1116 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range

>1M-10M
Units
Ibs/yr
Ibs/yr
Year

1986





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L


ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Chemical intermed ate; catalyst (HSDB)
Value

133
2.97


156
39
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BST






Notes
assumed persistent; BST = Biodegradessometimes/recacitrant







-------
Vernolate
CCL 3 Contaminant Information Sheet
                                                                                            EPA-OGWDW
     August 2009
Page 1117 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vernolate
12434
1929777
Attribute Scores 3-model Categorical Prediction
Potency Severity
6 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value

0.001

0.001











1,200
Units
mg/kg-d
mgJkg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date

1986













1991
Critical Effect

Decreased body weight in parental animals

Decreased weight











Details of toxic effects not reported other than lethal dose
value
Prevalence Magnitude ,,, „
7 5 NL'
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose; Basis = NOEL 1 mg/kg-d, UF = 1000, rat, oral (Stauffer Chemical Co., 1983)
Reference Dose
Reference Dose; Basis = NOEL/LEL, rat, whole body, MF = 1, UF = 1000 (Stauffer Chemical Co., 1983)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data


Rat; FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
Volume(issue)/page/year-,C321,1991
Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification






mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1




















Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer



7

Y/N
Y/N

W/L
W/L












Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vernolate
   CCL 3 Contaminant Information Sheet
                                                                                          EPA-OGWDW
     August 2009
Page 1118 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released
181,789


# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States
9


% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range


Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





Former herbicide (HSDB)
Value
38
425
3.84

3.08E-05
90
16
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BSA






Notes
BSA = Biodegrades slow with acclimation (PBT)







-------
Vinyl acetate
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1119 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyl acetate
4660
108054
Attribute Scores 3-model Categorical Prediction
Potency Severity
3 3
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



1







0.1




Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date











1966




Critical Effect



Altered weight







Behavioral - alteration of classical conditioning




Prevalence Magnitude ,,,
1 1 NL
HRL Ratio(s)
No data for calculating HRL ratio
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis = NOAEL, MF = 1 , UF = 100, rat, whole body (US EPA, 1 989)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level; oral study in rat; GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2B
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1995











Vol. 63; Cancer classifications were used for screening, but no related quantitative cancer risk data were
dentified for potency scoring.
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y


7,000

Y/N
Y/N

W/L
W/L
1995









IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vinyl acetate
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1120 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No data for calculating HRL
ratio)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T172, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler
794

# Sam pies

Amount
Released

16,057
3,068,589
# PWSs/Sites
sampled

0

#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects

0

% Samples with
detects

Number of
States

8
35
% PWSs/Sites
with detects

Not Detected

Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1B
>1B
Polymer intermec
Value

6.13
0.73

0.000511
20,000

Units
Ibs/yr
Ibs/yr
Year
1998
2002



Not Detected

Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects

Not Detected

Median value of
Detects

Not Detected

90% of
Detects

Not Detected

99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate; in hairspray (HSDB)
Units
length of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BFA






Notes
BFA = Biodegrades fast with acclimaton (BIODEG)







-------
Vinyl fluoride
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1121 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyl fluoride
2618
75025
Attribute Scores
Potency Severity

Prevalence Magnitude
5 8
Incomplete data for scoring
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value
















Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect

















3-model Categorical Prediction

HRL Ratio(s)
No HRL; No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Leve

Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





2A
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1995











Vol. 63
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer
Y




Y/N
Y/N

W/L
W/L










CACART; IARC

Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vinyl fluoride
   CCL 3 Contaminant Information Sheet
                                                                                               EPA-OGWDW
     August 2009
Page 1122 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No HRL; No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>1M-10M
XIM-10M
Polymer intermec
Value
1 5 days
24
1.2

0.12
12,99
61
Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate (HSDB); gas
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------
Vinyltoluene
CCL 3 Contaminant Information Sheet
                                                                                             EPA-OGWDW
     August 2009
Page 1123 of 1124
Contaminant
Substance Key:
Contaminant ID (CASRN):
Vinyltoluene
28159
25013154
Attribute Scores 3-model Categorical Prediction
Potency Severity
5 6
HEALTH EFFECTS DATA1
Non-cancer data
EPA OPP RfD
EPA IRIS (ITER) RfD
EPA HA RfD
RAISHE RfD
ATSDR (ITER), MRL
JMPR, maximum ADI
CEDIADI, ADI
ITER, TDI
Supplemental RfD-like value
CTDJPN Highest Chronic NOEL
Supplemental NOEL
RTECS Lowest Oral Chronic LOAEL
Supplemental LOAEL
HSDB Lowest Oral LD50
CTDJPN Lowest Oral LD50
RTECS Lowest Oral LD50
Value



0.006












Units
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg-d
mg/kg
mg/kg
mg/kg
Date
















Critical Effect



Nasal cavity- lesions












Prevalence Magnitude , „
67 L
HRL Ratio(s)
No water data
Notes
Reference Dose
Reference Dose
Reference Dose
Reference Dose; Basis = LOAEL, MF = 1, UF = 1000, mouse, nasal cavity (US EPA, 1987)
Minimal Risk Level
Acceptable Daily Intake
Acceptable Daily Intake
Tolerable Daily Intake
Supplemental Data
No Observed Effect Level
Supplemental Data
Lowest Observed Adverse Effect Level
Supplemental Data



Cancer Data
EPA Lifetime Cancer Risk, 104
RAISHE Slope Factor
OEHHA Slope Factor (oral)
EPA Slope Factor
EPA Carcinogen classification
ARC Carcinogen Classification





3
mg/L
(mg/kg-d)-1
(mg/kg-d)-1
(mg/kg-d)-1







1994











Vol. 60
Other Supporting Data
s contaminant on list of carcinogens?
s the contaminant on a list of reproductive
toxins?
EPAHA-DWEL
Health Reference Level (HRL)2
Health Reference Level (HRL)2 cancer

Y

42

Y/N
Y/N

W/L
W/L






Teratogen




UMD
Drinking Water Equivalent Level


1 Bolded data indicate value was used in attribute scoring
2 For the CCL process HRLs were calculated by converting the RfD or other dose to ug/L, assuming 2 L/day of water consumed by a 70 Kg adult, and a Relative Source Contribut on of 20%. For carcinogens, the concentration at the 1 0 "6 cancer risk was used.

-------
   Vinyltoluene
   CCL 3 Contaminant Information Sheet
                                                                                           EPA-OGWDW
     August 2009
Page 1124 of 1124
OCCURRENCE DATA1

# PWSs/Sites
sampled
#with Detects
% PWSs/Sites
with detects
Minimum value of
Detects
Maximum
value of
Detects
Median value of
Detects
90% of
Detects
99% of Detects
Finished Water Occurrence Data
UCMR finished water
NCOD Round 1 finished water
NCOD Round 2 finished water
NIRS finished water
































Ambient Water Occurrence Data
NAWQA ambient water
NREC ambient surface water
NREC ambient ground water
NREC ambient surface water
NREC ambient ground water
Application/Release
NCFAP Pesticide Application - total
TRI Release - surface water
TRI Release - total
Supplemental Water Data

HRL Ratios (No water data)
Production
CUSIUR Production Data
Use
Environmental Fate Parameters
T,a, Half life
Koc, Organic Carbon Partition Coefficient
log Kow, Octanol Water Partition Coeff.
Kd, Distribution coefficient
HLC, Henry's Law Constant
Water Solubility
% water PBT profiler


# Sam pies

Amount
Released



# PWSs/Sites
sampled



#with Detects

Units
Ibs/yr
Ibs/yr
Ibs/yr
#with Detects



% Samples with
detects

Number of
States



% PWSs/Sites
with detects



Minimum value of
Detects

Units
States
States
States
Minimum value of
Detects

Non-cancer:
Amount Range
>10M-50M
>10M-50M
Polymer intermec
Value
15
817
3.48

0.00785
89

Units
Ibs/yr
Ibs/yr
Year
1998
2002





Maximum
value of
Detects

Year
1997
2004
2004
Maximum
value of
Detects



Median value of
Detects



90% of
Detects



99% of Detects

Units for Mag
data

ug/L
ug/L
ug/L
ug/L

ug/L
ug/L
ug/L
Units for Mag
data
ug/L
ug/L
Notes







National Reconnaissance
National Reconnaissance
Notes
National Aggregate
National Aggregate
Notes



Median value of
Detects

99% of
Detects

Units for Mag
data

Cancer:



Notes





ate; insecticide component (HSDB)
Units
ength of time
L/kg
unitless
L/kg
atm-m3/mol
mg/L

Degradation
Code
BS






Notes
BS = Biodegrades s ow (PBT)







-------