United States
Environmental Protection
Agency
Contaminant Candidate List 3
Chemicals: Identifying the Universe
Office of Water (4607M) EPA 815-R-08-002 February 2008 - Draft www.epa.gov/safewater
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Table of Contents
1.0 INTRODUCTION 1
1.1 Background 1
1.2 Overview of the Data Source Assessment Factor Process 2
1.3 Assessment Factors 4
1.3.1 Relevance 4
1.3.2 Completeness 5
1.3.3 Redundancy 6
1.3.4 Retrievability 7
1.4 Supplemental Data Sources 8
1.5 Additional Information 10
2.0 THE CCL 3 CHEMICAL UNIVERSE SELECTION PROCESS 11
2.1 Chemicals in Occurrence and Health Effects Sources 11
2.2 Chemicals in Health Effects Sources Only 11
2.3 Chemicals in Occurrence Sources Only 12
2.4 Refining the Initial List of Chemicals 14
3.0 REFERENCES 16
4.0 APPENDICES 16
Appendix 1. CCL 3 All Data Sources - Assessment Table 17
Appendix 2. CCL 3 Universe of Data Sources 53
Appendix 3. CCL 3 Universe Supplemental Data Sources 59
Appendix 4. CCL 3 Data Source Descriptions 69
Table of Exhibits
Exhibit 1: Flow Chart of the Data Source Assessment Process 2
Exhibit 2: The Universe of Data Sources for the CCL Process 3
Exhibits: Examples of Retained and Redundant Sources 7
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Exhibit 4: Supplemental Sources that Meet the Assessment Factors of Relevance, Redundancy,
and Completeness, but not Retrievability 9
Exhibits: Overview of Data Evaluation for the CCL 3 Universe Selection Process 12
Exhibit 6: Example of Universe Data for Contaminants with Occurrence Data but no Health
Effects Data 13
Exhibit 7: Overview of Data Evaluation for the CCL 3 Universe Selection 15
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List of Acronyms and Abbreviations
ARS Alternate Crops and Systems (ARS)
ATSDR Agency for Toxic Substances and Disease Registry
CADW Canadian Drinking Water Quality
CCL Contaminant Candidate List
CCL 3 EPA's third Contaminant Candidate List
CCOHS Canadian Center for Occupational Health and Safety
CCRIS Chemical Carcinogenesis Research Information System
CDC Centers for Disease Control and Prevention
CDPR California Department of Pesticide Regulation
CEDI/ADI Cumulative Estimated Daily Intake/Acceptable Daily Intake
CERCLA Comprehensive Environmental Response, Compensation, and Liability Act
CERCLIS Comprehensive Environmental Response, Compensation, and Liability Information
System
CESARS Chemical Evaluation Search and Retrieval System
CICADs Concise International Chemical Assessment Documents
CPH Classification of Pesticides by Hazard
CUS/IUR Chemical update system/inventory update rule
DSSTox Distributed Structure Searchable Toxicity Public Database Network
EAFUS Everything Added to Food in the United States
EFDB Environmental Fate Databases
EMAP Environmental Monitoring and Assessment Program
EPA United States Environmental Protection Agency
FAO Food and Agriculture Organization
FDA United States Food and Drug Administration
FIFRA Federal Insecticide, Fungicide, and Rodenticide Act
GAP Genetic Activity Profiles
GRAS Generally Regarded As Safe
HA Health Advisories
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HEAST Health Effects Assessment Summary Tables
HEDS Human Exposure Database System
HPV High Production Volume
HSDB Hazardous Substances Data Bank
IARC International Agency for Research on Cancer
ICR Information Collection Rule
ILO International Labor Organization
IPCS International Programme on Chemical Safety
IRIS Integrated Risk Information System
IRPTC International Register of Potentially Toxic Chemicals
ITER International Toxiciry Estimates for Risk
JECFA Joint Expert Committee on Food Additives
JMPR Joint Meeting On Pesticide Residues
LCSS Laboratory Chemical Safety Summaries
MPR Maximum Permissible Risk
MRL Minimal risk levels (from ATSDR); or, Minimum reporting level, for analytical data
N Number of samples
NAS National Academies of Sciences
NAWQA National water quality assessment (USGS program)
NCEA National Center for Environment Assessment
NCFAP National Center for Food and Agricultural Policy
NCOD National contaminant occurrence database
NDWAC National Drinking Water Advisory Council
NHANES National Health and Nutrition Examination Survey (CDC)
NHATS National Human Adipose Tissue Survey
NIOSH National Institute for Occupational Safety and Health
NIRS National Inorganic and Radionuclide Survey
NLM National Library of Medicine
NOES National Occupational Exposure Survey
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NREC
NRC
NSF
NSI
NTP
OECD
OEHHA
OPP
OPPT
PAFA
PAN
PBT
PCBs
PCCL
PCS
PDF
PEAC
PELs
PPIS
PPMP
RAIS
REDDs
RTECS
SCLP
SDWIS
SIDS
SRC
SRD
SRS
National Reconnaissance of Emerging Contaminants
National Research Council
National Sanitary Foundation
National Sediment Inventory
National Toxicology Program
Organization for Economic Co-operation and Development
California Office of Environmental Health Hazard Assessment
Office of Pesticide Programs
Office of Pollution Prevention and Toxics
Priority-based Assessment of Food Additives
Pesticide Action Network
Persistent, Bioaccumulative, and Toxic Profiler
Polychlorinated biphenyls
Preliminary Contaminant Candidate List
Permit Compliance System
Pesticide Data Program
Palm Top Emergency Action for Chemicals
Permissible Exposure Limits
Pesticide Product Information System
Pesticide pilot monitoring program
Risk Assessment Information System
Reregistration Eligibility Decision Documents
Registry of Toxic Effects of Chemical Substances
Superfund Contract Laboratory Program
Safe Drinking Water Information System
Screening Information Data Sets
Syracuse Research Corporation
Source Ranking Database
Substances Registry System
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STORET STOrage and RETrieval
TEAM Total Exposure Assessment Methodology Study
TERA Toxicology Excellence in Risk Assessment
TOPKAT The Open Practical Knowledge Acquisition Toolkit
TRI Toxics Release Inventory
TSCA Toxic Substances Control Act
TSCATS Toxic Substances Control Act Test Submissions
UCM Unregulated contaminant monitoring
UCMR Unregulated Contaminant Monitoring Regulation
UCMR 1 First Unregulated Contaminant Monitoring Regulation
UCMR 2 Second Unregulated Contaminant Monitoring Regulation
UNEP United Nations Environment Programme
URCIS Unregulated Contaminant Information System
US United States of America
USDA United States Department of Agriculture
USGS United States Geological Survey
WERF Water Environment Research Foundation
WHO World Health Organization
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1.0 Introduction
The purpose of this document is to describe the process by which the United States
Environmental Protection Agency (EPA): 1) identified data resources for building the
Contaminant Candidate List (CCL) Chemical Universe; and 2) assessed contaminant-specific
information in these resources to identify over 6,000 contaminants for inclusion in the CCL
universe.
In the first part of this effort, data sources were identified in the reports and recommendations of
the National Academy of Sciences' National Research Council (NRC, 2001), the National
Drinking Water Advisory Council (NOWAC, 2004), a stakeholder report (AWWA, 2003), and
EPA's considerations of its statutory requirements. Through these reviews, 284 potential data
sources were identified that might provide relevant data to the CCL process for drinking water.
These sources were reviewed for the purpose of compiling a Universe of chemicals for
consideration in the CCL process, which will be discussed in Section 2. To evaluate the
usefulness of these 284 data sources, EPA developed and applied assessment criteria to select the
most appropriate data sources and identify contaminants for the CCL Universe.
1.1 Background
The NRC report provided general guidance for a broad approach to collect extensive information
in building the CCL Universe that included using diverse data sources that provide contaminant
lists and large data sets of health effects, occurrence information, and chemical properties. The
NDWAC recommendations built on the NRC recommendations and added more specific focus
and criteria to the process. NDWAC reviewed various approaches and recommended that a data
source compilation approach be used to aggregate on-line data sources. NDWAC noted that the
chemical CCL Universe should include those agents that have demonstrated or potential
occurrence in drinking water, or those agents that have demonstrated or potential adverse health
effects. To narrow the field of data sources compiled, NDWAC noted that the data and data
sources should have a reasonable link to adverse health effects and represent a reasonable
pathway to drinking water occurrence.
NDWAC recognized that the data compilation for the CCL Universe should focus on readily
available data (e.g., automated retrieval) and that multiple sources may provide similar (or
identical) data. Not all sources contain data in a retrievable format; hence, some valuable
sources will need to serve as supplemental sources to fill in data gaps during the CCL process.
NDWAC also noted that the data compilation process should be supplemented with surveillance
and nomination processes to enable inclusion of new and emerging contaminants. Further,
NDWAC provided basic guidance to review the completeness of data source documentation and
quality.
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Potential data sources were identified and compiled through EPA research in support of the
NDWAC process and with a stakeholder workshop sponsored by the American Water Works
Association. Some preliminary evaluations and recommendations also resulted from the
workshop. These efforts resulted in the listing of the 284 data sources that were assessed for the
CCL Universe.
1.2 Overview of the Data Source Assessment Factor Process
Exhibit 1 provides a schematic overview of the data source assessment process and the four
assessment factors: 1) Relevance, 2) Completeness, 3) Redundancy, and 4) Retrievability.
Exhibit 1: Flow Chart of the Data Source Assessment Process
CCL Universe- 284 Initial Data Sources
Relevance - Does this data source contain demonstrated
or potential health effects or occurrence or surrogate info?
Yes
, , (N=142)
Completeness - Does this data source have the
minimum record requirements - contact name, description
of the data elements, and how the data were obtained?
Yes
(N=130)
Redundancy - Does this data source contain information
identical to other more comprehensive sources?
No
(N=104)
Retrievability - Are the data in this source formatted for
automated retrieval?
No
(N = 142)
Yes
(N = 26)
Not Used
for CCL 3
Based upon EPA's statutory requirements and input from the NRC, NDWAC and the
stakeholder process, EPA developed assessment factors to evaluate data sources to ensure they
are relevant to the CCL process, complete in basic documentation, not redundant with other data
sources, and are formatted for automated retrieval. These factors were based upon the NDWAC
recommendation that: data sources should have data and information about actual or potential
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occurrence of contaminants in drinking water or source water and/or about health effects; the
CCL Universe should focus on readily available data; and the sources should meet EPA's
minimum guidelines for documentation and quality.
Each source was accessed on-line (or as provided by the source proprietor) and reviewed; basic
information about the source, its purpose, and the data elements it contained, was compiled and
documented. Every source was evaluated using all assessment factors. Sources that "answered
yes" to the assessment factor questions in Exhibit 1 moved forward in the process. Those
sources that met all four factors became the prime sources that form the "Universe of Data
Sources." Some 68 data sources were not retrievable. Of these, 65 were utilized for
supplemental analyses at other stages of the classification process. Three of the sources that were
not retrievable were also identified as "unique" or "exceptional" because of the importance of
their data, and they were also included in the Universe.
The 36 data sources that "answered yes" to all four assessment factors are listed in Exhibit 2.
The three unique and exceptional sources are identified in italics in the Exhibit. These are the 39
data sources that comprised the starting point for the CCL process. Each of these factors will be
discussed in more detail in Section 1.3.
Exhibit 2: The Universe of Data Sources for the CCL Process
Name of Data Source
Agency for Toxic Substances and Disease Registry (ATSDR) Comprehensive Environmental Response,
Compensation, and Liability Act (CERCLA) Priority List
ATSDR Minimal Risk Levels (MRLs)
Chemical Toxicity Database - Ministry of Health and Welfare, Japan
Chemical Update System/Inventory Update Rule (CUS/IUR) - EPA
Cumulative Estimated Daily Intake/Acceptable Daily Intake (CEDI/ADI) Database - US Food and Drug
Administration (FDA)
Database of Sources of Environmental Releases of Dioxin-Like Compounds in the United States - EPA
Distributed Structure Searchable Toxicity Public Database Network (DSSTox) - EPA
Everything Added to Food in the United States (EAFUS) Database - FDA
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) List - EPA
10
Generally Regarded As Safe (GRAS) Substance List - FDA
11
Guidelines for Canadian Drinking Water Quality (CADW): Summary of Guidelines - Health Canada
12
Hazardous Substances Data Bank (HSDB) - National Library of Medicine (NLM)
13
Health Advisories (HA) Summary Tables - EPA
14
High Production Volume (HPV) Chemical List - EPA
15
Indirect Additives Database - FDA
16
Integrated Risk Information System (IRIS) - EPA
17
International Agency for Research on Cancer (IARC) Monographs
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Name of Data Source
18
International Toxicity Estimates for Risk (ITER) Database - Toxicology Excellence in Risk Assessment
(TERA)
19
Joint Meeting On Pesticide Residues (JMPR) - 2001 Inventory of Pesticide Evaluations - World Health
Organization (WHO), Food and Agriculture Organization (FAO)
20
National Drinking Water Contaminant Occurrence Database (NCOD) - Round 1&2 - EPA
21
NCOD - Unregulated Contaminant Monitoring Regulation (TJCMR) - EPA
22
National Inorganics and Radionuclides Survey (NIRS) - EPA
23
National Pesticide Use Database - National Center for Food and Agricultural Policy (NCFAP)
24
National Reconnaissance of Emerging Contaminants (NREC) - United States Geological Survey (USGS)
Toxic Substances Hydrology Program
25
National Toxicology Program (NTP) Studies
26
National Water Quality Assessment (NAWQA) - USGS
27
OSHA 1988 Permissible Exposure Limits (PELs) - National Institute for Occupational Safety and Health
(NIOSH)
28
Pesticide Data Program (PDF) - United States Department of Agriculture (USDA)
29
Pesticides Pilot Monitoring Program (PPMP) - USGS/EPA
30
Risk Assessment Information System (RAIS) - Department of Energy - Chemical Factors
31
RAIS - Department of Energy - Health Effects Data
32
State of California Chemicals Known to the State to Cause Cancer or Reproductive Toxicity
33
Substances Registry System (SRS) - EPA
34
Syracuse Research Corporation (SRC) - BIODEG
35
The Toxics Release Inventory (TRI) - EPA
36
Toxic Substances Control Act (TSCA) List - EPA
37
Toxicity Criteria Database - California Office of Environmental Health Hazard Assessment (OEHHA)
38
University of Maryland - Partial List of Acute Toxins/Partial List of Teratogens
39
WHO Guidelines for Drinking Water Quality: Summary Tables
1.3 Assessment Factors
In this section, the rationale for the four Assessment Factors is set out in more detail. Examples
are also provided to illustrate their application.
1.3.1 Relevance
The Relevance assessment factor addresses the NOW AC and NRC principles for the CCL
Universe and evaluates whether a data source contains information on demonstrated or potential
occurrence of contaminants in the environment and/or demonstrated or potential human health
effects. Various surrogate data that may be used to evaluate potential occurrence are also
relevant. Some examples of relevant data sources include: International Toxicity Estimates for
Risk, which provides peer-reviewed toxicological data (demonstrated health effects); the
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National Inorganics and Radionuclides Survey (NIRS), an EPA survey of inorganic
contaminants in drinking water, a source of data on demonstrated occurrence in drinking water;
and the National Water Quality Assessment program, a nation-wide water-quality sampling
program conducted by the United States Geological Survey (USGS), that provides demonstrated
occurrence in source waters, or potential occurrence in drinking water. An example of a data
source that is not relevant to the CCL process is the Label Review Manual. This is simply a
guidance manual for reviewing pesticide labels. It does not contain any occurrence or health
effects information or even lists of agents to consider. Other examples include data sources that
provide toxicological data for aquatic macro-invertebrates but not data for mammalian or human
health effects. Such sources are not relevant at this stage of the process.
Another example of sources that are not relevant to the CCL process is simple lists of chemicals
without any indication (or application) of potential health effects or occurrence in water (e.g., the
National Information Services Corporation Structure and Nomenclature System). However,
some sources that are lists of chemicals may also provide health effects or occurrence
information. If the purpose of the list is to identify an adverse health effect or the potential for
occurrence, these may be relevant. For example, a source that is a list of teratogens by its nature
includes information regarding potential adverse health effects, even though it may not contain
actual health effects data elements. Related to occurrence, the High Production Volume list is a
list of chemicals that are produced at greater than one million pounds per year, indicative of the
potential for occurrence in the environment and drinking water.
Sources of information on physical/chemical properties that contain environmental fate data
(e.g., biodegradation rates) also may be useful surrogate information to indicate potential
occurrence and are considered relevant. However, sources that provide information only on
chemical properties that do not relate to environmental fate, such as the melting point for a
chemical, are considered not relevant.
Of the 284 data sources, 142 sources contain information relevant to the CCL Universe, and 142
do not. Therefore, 142 sources moved forward into the next step of the assessment.
1.3.2 Completeness
The Completeness assessment evaluates whether the data source provides complete, minimum
documentation and quality requirements. NOW AC recommended that each source should
include: 1) provision of the name of a person to contact about the data source (or contact
information); 2) a description of the data elements; 3) information on how the data were
obtained; and 4) meaningfulness and relevance of the data. (The "meaningfulness and
relevance" NOW AC recommendation is addressed by the Relevance assessment factor, so it is
not included in the Completeness assessment.) Also, data sources that provide documentation of
peer review are considered to satisfy the Completeness criteria. NDWAC specifically
recommended that an assessment of individual data elements within the data sources was not
appropriate at this stage of the CCL process. A more in-depth assessment of data quality may
occur at later stages of the CCL process, before a final CCL is produced.
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An example of a data source that did not pass the Completeness assessment was the
Compendium of Common Pesticide Names, because there was no documentation readily
available for how the data were obtained or compiled. A few sources were eliminated because
they are proprietary and none of the documentation is publicly available. These sites would have
been eliminated in subsequent steps for other reasons, as well. (Similarly, some sources that did
not pass the Relevance evaluation would have been eliminated by the Completeness assessment.)
Of the 142 data sources that meet the Relevance criteria, 12 sources did not meet the
Completeness assessment factor. These sources were not used to provide information to the
CCL Universe.
1.3.3 Redundancy
The Redundancy assessment factor evaluates whether data sources contain information that is
identical to (i.e., duplicates information from) other, more comprehensive data sources. An
example of a redundant source would be data contained in a state or regional data source that
were copied from a more comprehensive or representative national data source. Therefore, to be
considered redundant, a data source must contain data identical with respect to the identity of the
original data gatherer, time, place, method, outcome, and data manipulation or modification. For
example, the same data gatherer might conduct a survey of the same size, taken in the same
places, processed according to the same methods, showing the same results and manipulated the
same way, yet it would not be redundant if the surveys were done at different times. Note that if
two sources provide identical data elements, but one provides data for more contaminants, these
sources are considered Redundant, and the larger, more comprehensive, source is included.
Exceptions to this rule overlap into the Retrievability factor: if the smaller source is retrievable,
but the larger source is not, the smaller source may be used, in cases where the smaller source
contained all the relevant data. For example, EAFUS (Everything Added to Food in the United
States) and GRAS (Generally Regarded As Safe) are both part of the PAFA (Priority Based
Assessment of Food Additive Database). The data in EAFUS and GRAS are retrievable. PAFA
is a subscription source, and is not retrievable. Further, EAFUS and GRAS provide the relevant
information from PAFA, so EAFUS and GRAS were used, but PAFA was not.
Exhibit 4 shows a few examples of sources that met the Relevance and Completeness
Assessment Factors, but were determined to be Redundant and thus were excluded from the CCL
Universe. (All the sources, and their Assessment Factor evaluations are shown in Appendix 1.)
Of the 130 data sources that meet the Relevance and Completeness assessment factors, 26
sources are Redundant and were not included in the CCL Universe.
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Exhibit 3: Examples of Retained and Redundant Sources
1
2
3
4
Source Retained For CCL Universe
Consideration
OSHA 1988 PELs
BIOLOG, BIODEG, CHEMFATE,
and DATALOG - SRC
NCOD - Round 1&2 - EPA
IARC - Summaries and Evaluations
Source classified as Redundant
(Excluded from CCL Universe
Consideration)
Idaho Toxic and Hazardous
Substances - Idaho Division of
Building Safety
SRC - Environmental Fate Databases
(EFDB)
Unregulated Contaminant
Information System (URCIS) - EPA
INTOX Databank - International
Programme on Chemical Safety
(IPCS)
Comments
OSHA (PELs) is more
comprehensive
EFDB simply provides a link to, and
leads to, BIOLOG, BIODEG,
CHEMFATE, and DATALOG
URCIS was converted into NCOD
Round 1 database, so URCIS is no
longer needed
INTOX is a subscription source and
IARC is independently and publicly
available
1.3.4 Retrievability
The Retrievability assessment factor is an evaluation of whether the data in a source are
formatted for automated retrieval. For example, if data are stored in a tabular format, they may
be extracted and formatted, using software tools, and imported directly into a database for further
use. In contrast, many data stored in a text format require manual review and interpretation prior
to extraction and may require manual input into the database.
However, data sources that consist of relevant simple lists in text format, which can be easily
retrieved and imported, are considered to be Retrievable. Some text sources present occurrence
and health effects data in consistent layouts (albeit in paragraph style) and some use suitable
formats (i.e., HTML) and retrieval can be automated in some of these cases for select data. This
has been accomplished for some key sources (e.g., the Hazardous Substances Data Bank
(HSDB)) for a limited number of contaminants.
There are some unique considerations for the retrievability of some CCL data sources. For
example, the Storage and Retrieval System (STORET) is an EPA data warehouse from which the
data are readily retrievable. However, many data fields in STORET are highly variable to
accommodate the many original sources of data that STORET captures. STORET data are often
not nationally representative and the data often overlap with nationally representative water data
such as MRS. The data also provide results based on different analytical methods and study
goals, and these data in aggregate will require additional evaluation and documentation related to
their inclusion in STORET. Based on these special processing and analysis requirements,
STORET is designated as a supplemental source to be used in the next level of CCL evaluations.
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Another factor limiting the retrievability of many sources is that they are not readily available
publicly. NDWAC expressed concern for transparency and for the ability of the public to review
the types of data used in the CCL process. Many sources require a subscription and this may
limit public access. Sources that were identified as subscription sources, i.e., sources that would
require payment for use, were classified as not Retrievable as they are not readily accessible to
the public.
Of the 104 data sources that are Relevant, Complete and not Redundant, 68 sources do not meet
the Retrievability assessment factor. Data from sources that meet the Relevance, Completeness
and Redundancy assessment factors, but not the Retrievability factor, may be important to fill
gaps in the compilation process, and their data were utilized in later steps in the CCL process.
Hence, these sources are reserved as Supplemental sources, as described in the next section.
Also, as noted earlier in this report, 3 of the 68 sources that were not retrievable, were considered
unique and exceptional and were added to the Universe data sources (see Exhibits 1 and 2),
leaving 65 sources reserved as Supplemental.
After analyzing the initial 284 data sources for relevance, completeness, redundancy and
retrievability, we are left with 39 data sources in our "Universe of Data Sources." This includes
the three unique or exceptional data sources not meeting the retrievability criterion.
1.4 Supplemental Data Sources
As noted in Section 2, the sources that meet all of the assessment factors except for
Retrievability are considered supplemental sources that may be used to provide data at other
steps in the CCL process. For example, in the Universe to the Preliminary CCL (PCCL)
screening process, it may prove worthwhile to consult a toxicological summary such as the
Registry of Toxic Effects of Chemical Substances (RTECS) to obtain data not already available
in the Universe database from a retrievable source for particular contaminants. Exhibit 4 lists the
65 Supplemental data sources. Sources that are not retrievable because they require a
subscription (11) are identified in the second section of the Exhibit.
The 284 data sources also include a number of bibliographic sources (bibliographic search
engines) that were not classed as relevant to the Universe data compilation step of the CCL. This
is because they consist of text (titles and/or abstracts) on many subjects not pertaining to CCL,
and what data they may contain are inconsistently presented. These are partly retrievability
issues as well. However, depending on the data needs at various points in the CCL process, such
bibliographic sources and search engines (i.e., "PubMed", Science Direct) were used to fill in
data gaps in the screening and classification processes. A total of 33 supplemental sources were
utilized in other stages of the CCL classification process.
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Exhibit 4: Supplemental Sources that Meet the Assessment Factors
of Relevance, Redundancy, and Completeness, but not Retrievability
Supplemental Sources that Meet the Assessment Factors of Relevance, Redundancy,
and Completeness, but not Retrievability
1
10th Report on Carcinogens - NTP
2
Alternate Crops and Systems (ARS) Pesticide Properties Database - USDA
3
ATSDR Internet HazDat - Site Contaminant Query
4
ATSDR Toxicological Profiles
5
California Department of Pesticide Regulation (CDPR)
6
Chemical Carcinogenesis Research Information System (CCRIS) - NLM
Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) -
EPA
Concise International Chemical Assessment Documents (CICADs) - IPCS, WHO, International Labor
Organization (ILO), United Nations Environmental Programme (UNEP)
9
EC Water Directive - European Community
10
Endocrine Disrupter Priority Setting Database - EPA
11
Environmental Monitoring and Assessment Program (EMAP) - EPA
12
Genetic Activity Profiles (GAP) Database - EPA
13
GENE-TOX - NLM
14
Guidelines for Canadian Drinking Water Quality (CADW): Supporting Documentation - Health Canada
15
Health Advisory Documents - EPA
16
Health and Safety Guides - WHO, ILO, UNEP, Canadian Center for Occupational Health and Safety
(CCOHS)
17
Health Effects Assessment Summary Tables (HEAST) - EPA, National Center for Environment Assessment
(NCEA)
18
High Production Volume (HPV) Challenge Program Robust Summaries and Test Plans - EPA
19
Human Exposure Database System (HEDS) - EPA
20
Information Collection Rule (ICR) Federal Database - EPA
21
International Register of Potentially Toxic Chemicals (IRPTC PC) - Data Profiles - UNEP Chemicals
22
Joint Expert Committee on Food Additives (JECFA) - Monographs and Evaluations - WHO, FAO
23
Joint Meeting On Pesticide Residues (JMPR) - Monographs of Toxicological Endpoints - WHO, FAO
24
Laboratory Chemical Safety Summaries (LCSS) - Howard Hughes Medical Institute and National Academies
of Sciences (NAS)
25
National Health and Nutrition Examination Survey (NHANES) - Centers for Disease Control and Prevention
(CDC)
26
National Human Adipose Tissue Survey (NHATS) - EPA
27
National Institute for Occupational Safety and Health (NIOSH) - Index of Occupational Health Guidelines for
Chemical Hazards
28
National Occupational Exposure Survey (NOES) - CDC
29
National Sediment Inventory (NSI) - EPA
30
National Toxicology Program (NTP) Health and Safety Profiles
31
Office of Pollution Prevention and Toxics (OPPT) Chemical Fact Sheets - EPA
32
Organization for Economic Co-operation and Development (OECD) Integrated HPV Database
33
Permit Compliance System (PCS) Database - EPA
34
Persistent, Bioaccumulative, and Toxic Profiler (PBT Profiler) - EPA
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Identifying the Universe February 2008 - DRAFT
Supplemental Sources that Meet the Assessment Factors of Relevance, Redundancy,
and Completeness, but not Retrievability
35 Pesticide Action Network (PAN) Pesticide Database
36
Pesticide Handler Exposure Database - EPA
37
Pesticide Product Information System (PPIS) - EPA
38
Pesticides Tolerance Index System - EPA
39
Priority Substances Assessment Program - Health Canada
40
Registry of Toxic Effects of Chemical Substances (RTECS)
41
Reregistration Eligibility Decision Documents (REDDs) - EPA Office of Pesticide Programs (OPP)
42
Rijksinstituut voor Volksgesondheid en Milieu (RIVM) Maximum Permissible Risks (MPRs) Report
43
Safe Drinking Water Information System (SDWIS) - EPA
44
Screening Information Data Sets (SIDS) - OECD
45
Source Ranking Database (SRD) - EPA
46
State Drinking Water Data Sets - EPA
47
State of New Jersey Hazardous Substances Right to Know Fact Sheets
48
STORET - STORage and RETrieval - EPA
49
Superfund Contract Laboratory Program (SCLP) Water/Soil Data - EPA
50
Total Exposure Assessment Methodology Study (TEAM) - EPA
51
Toxic Substances Control Act Test Submissions (TSCATS) - EPA
52
US Army Center for Health Promotion and Medicine Detailed Chemical Fact Sheets
53
WHO Guidelines for Drinking Water Quality: Chemical Aspects: Index of Chemicals
54 WHO Recommended Classification of Pesticides by Hazard (CPH)
Subscription Sources
1
Chemical Evaluation Search and Retrieval System (CESARS) - CCOHS
2
CrossFire BEILSTEIN - MDL Information Systems
3
Derek - LHASA Limited
4
Dictionary of Substances and Their Effects - Knovel
5
National Sanitary Foundation (NSF) - Additives Standards 60 and 61
6
Palm Top Emergency Action for Chemicals (PEAC-CW System) - Federal Technical Support Working
Group
7
Priority-based Assessment of Food Additives (PAFA) Database - FDA
STN - CHEMLIST/HCHEMLIST - Regulated Chemical Listing
9
The Open Practical Knowledge Acquisition Toolkit (TOPKAT) - Accelrys
10
TOMES PLUS, MICROMEDEX - Thomson-Micromedex
11
Water Environment Research Foundation (WERF) Toxicity Datasheets
1.5 Additional Information
A detailed summary of the assessment process for the 284 sources is presented in the appendices
to this report. There are four appendices that summarize information about the data sources and
the assessment process. Appendix 1 is a list of the 284 sources along with notes discussing
whether the source satisfies the four assessment factors, and, if not, why not. Appendix 2
provides summary information about the data sources that meet all of the assessment factors and
that will populate the CCL Universe. Appendix 3 shows supplemental data sources that met the
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first three requirements, but were not considered readily retrievable. Appendix 4 includes more
descriptive information about the purpose and scope of the 284 data sources, and provides
background information for each source, including details on the source proprietor, a description
of the source, the format of the source, and the data elements included in each.
2.0 The CCL 3 Chemical Universe Selection Process
The purpose of this section is to describe the decision process that EPA used to develop the
Universe of chemicals identified from the 39 data sources (the "Universe of Data Sources")
selected, as described in Section 1. The data sources, classified by whether they provided
occurrence or health effects data, produced a compilation of 25,980 unique substances. Because
of the large number of substances, EPA developed a pre-Universe selection process that is
described in the following sections.
Exhibits 5 and 7 provide schematic diagrams that depict the two phases of the selection process
for the "Universe of Chemicals." The selection process represented in Exhibit 5 generated an
initial compilation of the Chemical Universe, but included some substances that were not unique
chemicals because they were mixtures, redundant water soluble ions, or different valence states
of the same element. Accordingly, the process represented by Exhibit 7 was used to refine the
initial compilation and generate the final CCL 3 Universe of Chemicals.
2.1 Chemicals in Occurrence and Health Effects Sources
The first stage in the process, as illustrated in Exhibit 5, identified approximately 7,300
chemicals that were present in both health effects and occurrence data sources. These chemicals
were automatically placed in the preliminary Chemical Universe to be further evaluated for
screening to the PCCL. Since only about 1/3 of the chemicals were in both health effects and
occurrence data sources, the rest of the approximately 18,600 chemicals left in the pre-Universe
were examined more closely to determine whether they were found only in health effects data
sources or only in occurrence data sources.
2.2 Chemicals in Health Effects Sources Only
Approximately 5,100 chemicals were in health effects data sources only. Many of these
chemicals were biochemical compounds (e.g. amino acids, sugars, steroids); mixtures and
natural products (e.g. coal tar, petroleum related substances, rocks, stone, wool); and other
entries that were identified as unique "substances" in the data sources but were not chemicals
(e.g. turbidity, boot and shoe manufacture, surgical implants). Once the chemicals were
categorized and evaluated, EPA placed the chemicals of greatest toxicological concern in the
CCL Chemical Universe, even though there was no known link to occurrence information. The
criteria for selecting contaminants that are of greatest toxicological concern are described in
detail in the EPA CCL 3 report entitled, "CCL 3 Chemicals: Screening to a PCCL." Many
chemicals fell in this category because of their classification as potential carcinogens. A total of
122 chemicals were added to the initial version of the CCL Chemical Universe through this
process.
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CCL 3 Chemicals:
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EPA815-R-08-002
February 2008 - DRAFT
Exhibit 5: Overview of Data Evaluation for the CCL 3 Universe
Selection Process
CCL Universe of Chemicals- Evaluation of Chemical Occurrence and Health
Effects Data
Universe of Data Sources
# of Unique Chemicals = 25,980
Is the chemical found in an occurrence
and HE source?
Chemicals in HE sources
5,107
Is the Chemical of Toxicological Concern:
Chemicals in Occurrence sources
13,544
Chemicals Not
Added to
Universe
(18,260) )
Is it found
in a finished water
or ambient water
source?
No/ Is it found N. No^/Is it produced
in a release data ^—^^in amounts > 1 bil.
source? / \ Ibs/year
2.3 Chemicals in Occurrence Sources Only
The chemicals found only in occurrence sources were also categorized. The approximately
13,500 chemicals with only occurrence data are a diverse group, comprised of many different
types of chemicals. Production data sources account for 70% of the total, and others are from
various finished water, ambient water, environmental release, environmental property, and food
additive data sources.
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EPA-OGWDW
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Identifying the Universe
EPA815-R-08-002
February 2008 - DRAFT
Exhibit 5 also shows several groups of chemicals that were added to the Universe of chemicals
even though the data sources lacked information on health effects. These included the following
groupings:
• Chemicals with Finished or Ambient Water Data
• Chemicals with Release Data
• Chemicals with High Production Volumes
Examples of key types of chemicals with only occurrence data are shown in Exhibit 6. The
chemicals with finished or ambient water data (42) were added to the Universe despite the lack
of health effects information in the data sources because of their demonstrated occurrence in
ambient or potable water. In addition, disinfection byproducts (e.g., from EPA's DSSTox DBF
lists) and water treatment additives (e.g., National Sanitary Foundation (NSF) Standard 60) were
added to the Chemical Universe. While these chemicals may not have demonstrated occurrence
data in the Universe of Data Sources, they are considered to have "default" occurrence data
because they are formed in, or intentionally added to drinking water supplies.
Exhibit 6: Example of Universe Contaminants with Occurrence Data
but no Health Effects Data
Occurrence Data
Type
Finished and Ambient
Water data
Environmental
Release
Production
Type of Data; Typical Source
Measured Water Occurrence;
UCMR, NAWQA
Amount Released; TRI, Pesticide
Application
Annual Production Volume; CUS/IUR
Number of Chemicals
Without Health
Effects
42
36
9,344
The 36 chemicals with an environmental release data source (e.g., those on the Toxics Release
Inventory or with pesticide application data) were also added to the Universe of chemicals.
Thirty-six chemicals met this criterion and were added to the CCL Chemical Universe.
Of the approximately 9,400 chemicals with only production information, only 191 were
produced in extremely high volumes (greater the 1 billion pounds per year). The 9,400
contaminants with production data consist of the following types: organometallics, elements,
non-elemental inorganics, salts of organic acids, organics (including: oils, fatty acids, dyes), and
mixtures (petroleum related compounds, hydrocarbons, and others). Many are predominantly
organic components and salts of organic acids, and over half of the chemicals are complexes of
elemental constituents. For example, there were about 750 sodium or potassium salt compounds
alone. In these cases, health effects data are not available for the exact compound, but are
generally available for other related compounds or the key ion or elemental constituent (e.g.,
sodium). Nearly all elements found in inorganic or organic salts are represented in the Universe
by other compounds with both health effects and occurrence data. Only 10 elements (excluding
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Identifying the Universe February 2008 - DRAFT
the obvious, such as hydrogen and oxygen, and the inert gasses krypton, neon, and xenon) did
not otherwise have representative compounds with health effects data in the universe. EPA added
europium, gadolinium, gold, lanthanum, praseodymium, platinum, polonium, samarium,
terbium, and yttrium to the Universe. After consideration of the diversity of the chemicals with
production data and the amounts produced on a yearly basis, a decision was made to move only
those produced at greater than 1 billion pounds per year to the CCL Chemical Universe.
After examining the data on the chemicals with only occurrence data, a total of 269 additional
chemicals were added to the CCL 3 Chemical Universe. The rest of the substances included in
the original data sources were not included in the Universe.
2.4 Refining the Initial List of Chemicals
The initial selection process described in Exhibit 5 brought into the CCL Universe of Chemicals
all substances from the data sources that met the defined selection criteria. This included
regulated as well as unregulated compounds, mixtures, and some substances that were not really
chemicals. Accordingly the process diagramed in Exhibit 7 was used to refine the initial list.
The first step in the refinement process was to remove chemicals with a National Primary
Drinking Water Regulation. These contaminants are already regulated; thus, their inclusion in
the CCL process is clearly unnecessary. This step removes a large number of chemicals (1,009),
more than the number covered by the primary standards, because of the form of the chemicals in
the compilation. For example, the chemicals removed include approximately 780 radionuclides
that are regulated as alpha and beta emitters, many redundant ionic and valence state entries for
elements and inorganic chemicals, and entries for individual polychlorinated biphenyls (PCBs)
that are regulated as total PCBs.
The second step was to remove substances that are considered a mixture of chemicals. A
mixture in this case is defined as a combination of two or more chemicals/items that are not
defined as a unique substance. Substances that fell in this category included "chlorinated
compounds, alcohols c>14, coal-tar-containing shampoo, petroleum-related substances, resin
acids, rosin acids, and guar gum," for example. Undefined mixtures, such as "diesel engine
exhaust" were also included in this group.
The third step removed "non-chemically defined" entries from the initial list. Examples of the
type of items in this category include: "solar radiation, wood dust, surgical implants, and welding
fumes." Some of these substances are present in the data sources because they have been
evaluated for their potential to cause cancer.
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EPA815-R-08-002
February 2008 - DRAFT
Exhibit 7: Overview of Data Evaluation for the CCL 3
Universe Selection
CCL Universe of Chemicals- Refinement of Initial Compiation
Does the contaminant have an NPDWR?
Yes = 1,009*
No = 6,711
Is the contaminant part a mixture of chemicals?
Yes = 430
No = 6,281
Is the contaminant non-chemically defined?
Yes = 276
No =6,005
Is the contaminant biological?
Yes = 2
No = 6,003
"Includes ~780 radionuclides that are regulated as alpha and beta emitters, many redundant ionic and valence state entries for
elements and inorganic chemicals, and entries for individual PCBs that are regulated as total PCBs.
The final step removed biological agents from the initial list. Contaminants in this category are
biological organisms that are being evaluated as part of the CCL 3 Microbiological Universe.
Entries for biological entities were uploaded from the Universe of data sources from various
health effects data sources and pesticide data sources. (Many biological entities were removed
as non-chemically defined, as well.)
After applying the process shown in Exhibit 7, l,717chemicals or substances were removed from
the initial Chemical Universe leaving approximately 6,000 chemicals to be evaluated. EPA also
published a Federal Register announcement requesting nominations from the public for chemical
and microbial contaminants that should be considered for CCL 3. The Agency received
information from 11 organizations and individuals on 174 nominated contaminants that included
150 chemical and 24 microbial contaminants. The Agency was already considering 132 of these
contaminants in the CCL process. EPA processed the nominated contaminants through the same
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steps used for the other contaminants considered for the draft CCL 3. Nominated contaminants
that were regulated or did not meet any of the other decision criteria to identify the universe were
not considered. The approximately 6,000 chemicals were carried forward for the next stage of
the CCL process whereby screening criteria are applied to select the PCCL using the available
health effects and occurrence data. This process is discussed in a companion support document,
the "CCL 3 Chemicals: Screening to a PCCL" (USEPA, 2008).
3.0 References
AWWA. 2003. CCL Workshop Report-Review of the Information Resources. June 2003.
NOW AC. 2004. National Drinking Water Advisory Council Report on the CCL Classification
Process to the U.S. Environmental Protection Agency. May 19, 2004
NRC. 2001. Classifying Drinking Water Contaminants for Regulatory Consideration. National
Academies Press. Washington. DC.
USEPA. 2008. Contaminant Candidate List 3 Chemicals: Screening to a PCCL. EPA 815-R-08-
003. Draft. February 2008.
4.0 Appendices
Appendix 1. CCL 3 All Data Sources - Assessment Table
Appendix 1 provides a listing of the 284 data sources and notations indicating whether a
source satisfied the four assessment factors and, if not, which factors were not satisfied and why.
Appendix 2. CCL 3 Universe of Data Sources
Appendix 2 provides a summary of information about the 39 data sources that met the
assessment factors, or were deemed unique and exceptional, and that were used to populate the
CCL 3 Universe.
Appendix 3. CCL 3 Universe Supplemental Data Sources
Appendix 3 shows the supplemental data sources that met the first three assessment factors
but contained data not considered readily retrievable. While not used for compiling the
Universe, these data sources were used to supplement contaminant evaluations during stages of
the CCL process.
Appendix 4. CCL 3 Data Source Descriptions
Appendix 4 includes descriptive information about each of the data sources.
Page 16 of 229
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Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
1
2
4
3
5
9
6
Data Source Name
10th Report on Carcinogens - NTP
8(e) TRIAGE Chemical Studies
Database - OPPT
Aerometric Information Retrieval
System/Air Quality Subsystem
(AIRS/AQS)
AGRICultural Online Access
(AGRICOLA)
All the Virology on the WWW
Alternate Crops and Systems
(ARS) Pesticide Properties
Database
Analytical ABSTRacts (ANABSTR)
Assessment Factor Evaluation
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the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on air emissions, which
may indicate potential occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
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This source is not redundant.
This source is not redundant.
This source is redundant with Idaho
Toxic and Hazardous Substances -
Idaho Division of Building Safety
(source 100).
This source is redundant with
Cambridge Scientific Abstracts
(source 15), but that source is a
subscription, whereas this source is
free of charge.
This source is not redundant.
This source is not redundant.
This source is not redundant.
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EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
7
8
10
11
12
13
123
Data Source Name
Aquatic Pollution and
Environmental Quality -
Cambridge Scientific Abstracts
AQUatic toxicity Information
Retrieval (AQUIRE)
ASFA 3: Aquatic Pollution and
Environmental Quality -
Cambridge Scientific Abstracts
Assessment Tools for the
Evaluation of Risk (ASTER)
ATSDR CERCLA Priority List
ATSDR Internet HazDat - Site
Contaminant Query
ATSDR Minimal Risk Levels
(MRLs)
Assessment Factor Evaluation
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subjects that may not pertain directly to
CCL, and its data elements are
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This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it only contains
information on ecological toxicity.
This source is considered relevant for
the CCL Universe because the basis
for developing this list is ATSDR's
prioritization of chemicals found at NPL
sites and that ATSDR believes may
pose a human health risk.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements (MRL) derived from
toxicological studies.
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ECOTOX (source 57).
This source is identical to Aquatic
Pollution and Environmental Quality
Cambridge Scientific Abstracts
(source 7).
This source is not redundant.
This source is not redundant.
This source is not redundant.
These data are also represented in
the ATSDR Toxicological Profiles;
however, these data are tabular
while the Profiles are monographic.
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CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
210
243
14
15
16
272
17
Data Source Name
ATSDR Toxicological Profiles
AwwaRF Project Reports
Bad Bug Book
Base de Dados Tropical (BDT)
Bergey's Manual of Systematic
Bacteriology
Biennial Reporting System
BIOBUSINESS Biological
Abstracts Database
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CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
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This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
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This source is not redundant.
This source is not redundant.
This source is not redundant.
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EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
18
19
20
21
235
22
23
Data Source Name
Biological Sciences - Cambridge
Scientific Abstracts
BIOSIS Biological Abstracts and
BIOSIS Previews
Bugs
CAB Abstracts - CABI Publishing
California Department of Pesticide
Regulation (CDPR)
CANCERLIT
Carcinogenic Potency Project
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This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
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CCL, and its data elements are
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This source does not meet relevance
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because it contains only information on
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This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
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This source is considered relevant for
the CCL Universe because it contains
a list of bioactive compounds.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
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This source is considered relevant for
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This source is not redundant.
This source is not redundant.
This source is not redundant.
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EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
238
231
29
30
24
28
285
36
42
Data Source Name
Case/MCase/MC4PC
Center for Food Safety and
Applied Nutrition (CFSAN)
Chemfinder
Chemical Backgrounder
Chemical Carcinogenesis
Research Information System
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Chemical Evaluation Search and
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Chemical Hazard Response
Information System
Chemical Information System
(CIS)-ILO/OSHIC
Chemical Registry System (CRS)
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3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
the results of carcinogenicity and
mutagenicity studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is no longer available
online.
This source is considered relevant for
the CCL Universe because it is an
interface to other information in EPA's
SRS system.
>*
u
£ a
Jl
^11
OL
X
X
X
X
X
X
X
=" e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is no longer available
online.
This source is redundant, as it is
wholly available as part of
Substance Registry System (SRS)
(source 203).
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
"5
H
£ 01
£ *
1 31
r
Unknown
Y
Unknown
N
Y
Y
Unknown
Unknown
Y
O
II
Q 1
M
fCT
U_
s
N
Y
Y
N
Y
Y
N
NA
Y
>:
to !5
a! «
1 5
S i
&
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
31
32
33
283
34
37
25
245
Data Source Name
Chemical Toxicity Database -
Ministry of Health and Welfare,
Japan
Chemical Update System (CUS)
Chemical Update
System/Inventory Update Rule
(CUS/IUR)
Chemicals in Commerce
Information System (CICIS) -
Toxic Substances Control Act
Inventory
ChemlDplus - Chemical
Clinical Virology
Communicable Disease Report
(CDR) - United Kingdom
Communicable Disease Reports
(CDR) - Australia
Assessment Factor Evaluation
5 1 B
1 s£
o "> "
s 8"-
<
X
X
s
« c
% |
g Si
£
X
X
X
X
§1
1 i
~Sj o.
nf X
"- UJ
This source is considered relevant for
the CCL Universe because it contains
data elements (LD50, NOEL) from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
information on production volume,
which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
information on production volume,
which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it is a list of
chemicals in production.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
>*
o
ll
*ti
OL
X
X
X
X
X
X
•o ™
"fl> X
o: uj
This source is not redundant.
This source is redundant with
CUS/IUR (source 33).
This source is not redundant.
The source is redundant with TSCA.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
eets
leteness
Sf
o
O
X
X
X
X
X
X
sntation of
Review
ll
r
Y
Unknown
Unknown
Unknown
Y
Y
Unknown
Unknown
til NDWAC
rements
1 3
fCT
u_
s
Y
N
Y
Y
Y
Y
N
N
>:
to !5
1 i
si
&
X
X
S? c
1= O
5C
£uj
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval. This
source is retrievable through CUS/IUR.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 22 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
755
38
276
35
27
39
41
26
44
Data Source Name
Compendium of Pesticide
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)
Computer Retrieval of Information
on Scientific Projects
Concise International Chemical
Assessment Documents (CICADs)
Contaminant Exposure and Effects
- Terrestrial Vertebrates (CEE-TV)
Database
Control of Communicable
Diseases Manual; 1 7 ed.
CrossFire BEILSTEIN
Cumulative Estimated Daily
Intake/Acceptable Daily Intake
(CEDI/ADI) Database
Current Contents Search - Life
Sciences - ISI
Assessment Factor Evaluation
5 1 B
1 s£
o "> "
s 8"-
<
X
s
« c
% |
g Si
£
X
X
X
X
X
§1
1 i
~Sj o.
nf X
"- UJ
This source is considered relevant for
the CCL Universe because it contains
a list of bioactive compounds.
This source is considered relevant for
the CCL Universe because it contains
information on potential contaminant
occurrence at superfund sites.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
health effects data.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
>*
o
ll
*ti
OL
X
X
X
X
X
X
X
X
X
•o ™
"fl> X
o: uj
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
eets
leteness
Sf
o
O
X
X
X
X
X
X
sntation of
Review
ll
r
Unknown
Y
Unknown
Y
N
Y
Y
Y
N
til NDWAC
rements
1 3
fCT
u_
s
N
Y
N
Y
Y
Y
Y
Y
N
>:
to !5
1 i
si
&
X
X
S? c
1= O
5C
£uj
This source meets retrievability criteria
because it is in HTML format and can be
extracted in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 23 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
46
241
48
47
49
51
45
Data Source Name
Database of Sources of
Environmental Releases of Dioxin-
Like Compounds in the United
States
Derek
Derwent Crop Protection File
(Derwent CROPU)
Derwent Crop Registry File
(Derwent CROPR)
Derwent Drug File (Derwent
DRUGU)
Design Institute for Physical
Property Data (DIPPR)
Developmental and Reproductive
Toxicology/Environmental
Teratology Information Center
(DART®/ETIC) Database
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
Meets
Relevance
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
information on air emissions, which
may indicate potential occurrence.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Unknown
Unknown
Unknown
Unknown
Y
Y
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
Meets
Retrievability
X
S? c
1= O
1 1
'£ "§•
& i±i
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 24 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
50
53
52
242
256
56
57
63
Data Source Name
Dictionary of Substances and
Their Effects - Knovel
Distributed Structure Searchable
Toxicity Public Database Network
(DSSTox)
Division of Bacterial and Mycotic
Diseases (DBMD) - Disease
Information Listing
EC Water Directive
Ecological Incident Information
System
Ecology of Aquatic Hyphomycetes
ECOTOX - A Database of Toxic
Effects to Aquatic and Terrestrial
Species
Elsevier BIOBASE
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
Meets
Relevance
X
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
regulatory limits for contaminants in
drinking water.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Unknown
Y
Unknown
Unknown
Y
Y
Y
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 25 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
65
59
68
60
58
258
61
Data Source Name
EMBASE
Endocrine Disrupter Priority
Setting Database (EDPSD)
Environmental Abstracts -
LexisNexis Academic and Library
Solutions
Environmental Data Registry
(EDR)
Environmental Defense Fund
(EOF) Chemical Profiles
Environmental Fate Databases
Environmental Health Criteria
(EHC) Monographs
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
X
X
X
if
if
"- UJ
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies and unique
elements derived for measurements of
contaminants in water, providing an
indicator of occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on potential health effects.
This source is considered relevant for
the CCL Universe because it contains
environmental fate data, providing an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements (LDx, LO(A)EL,
NO(A)EL) from toxicological studies.
Meets
Redundancy
X
X
X
X
X
>• c
Q rr
H
•0 Q.
fli X
Q: UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant with
BIOLOG, BIODEG, CHEMFATE,
and DATLOG. EFDB simply
provides a link to, and leads to,
BIOLOG, BIODEG, CHEMFATE,
and DATALOG.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
Meets
Completeness
X
X
X
X
X
Documentation of
Peer Review
Y
N
N
N
N
Unknown
Y
Meets All NDWAC
Requirements
Y
Y
N
Y
N
Y
Y
Meets
Retrievability
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 26 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
62
64
67
66
69
70
71
Data Source Name
Environmental Information
Management System (El MS)
Environmental Monitoring and
Assessment Program (EMAP)
Environmental Monitoring Methods
Index (EMMI)
Environmental Mutagen
Information Center Database
(EMIC)
Environmental Pollution - Elsevier
Science
Environmental Science and
Technology
Environmental Sciences and
Pollution Management -
Cambridge Scientific Abstracts
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
§1
1 2
& ra
~S a.
nt x
"- UJ
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant
because it contains geographical and
water quality data, providing an
indicator of potential occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
£§
H
l|
"fl> X
o: uj
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Y
Y
Y
Y
Y
N
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
Meets
Retrievability
X
S? c
•— o
•o '•%
„ ™
oi ra
£ °-
£m
This source meets retrievability criteria
because it is in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 27 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
55
72
54
73
274
289
263
75
74
Data Source Name
European Inventory of Existing
Commercial Substances (EINECS)
Information System
Eurosurveillance
Everything Added to Food in the
United States (EAFUS) Database
Extension TOXicology NETwork
(EXTOXNET)
Facilities Index Data System
Federal Insecticide, Fungicide,
and Rodenticide Act (FIFRA) List
Food Commodity Intake Database
Food Quality Protection Act
(FQPA) - "Cumulative to
Pesticides" List
FoodNet
Assessment Factor Evaluation
3 | Z
<» 01 3
%$ %
1 %"-
<
X
X
8
« c
d) 5
1 5
^&
X
X
X
X
M
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3J ra
ai a.
£ *
01 LU
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
>*
u
£ a
Jl
^11
OL
X
X
X
X
X
X
X
X
=" e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant with the
list of contaminants in FIFRA.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
N
Y
Y
N
Unknown
Unknown
N
Unknown
Y
O
II
a i
M
fCT
U_
s
N
Y
Y
N
N
Y
N
Y
Y
>:
to !5
a! «
1 5
S i
£
X
X
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
277
77
81
76
78
79
80
82
Data Source Name
Gastrointestinal Absorption
Database
GenBank® - National Center for
Biotechnology Information
Generally Regarded As Safe
(GRAS) Substance List
Genetic Activity Profiles (GAP)
Database
GENE-TOX
Genomes and Databases
Global Infectious Disease and
Epidemiology Network (GIDEON)
Ground Water On-Line - National
Ground Water Association
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
Meets
Relevance
X
X
X
if
if
"- UJ
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
This source is considered relevant for
the CCL Universe because it contains
information on mutagenicity, which
may be an indicator of potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
information on mutagenicity, which
may be an indicator of potential health
effects.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
Documentation of
Peer Review
Unknown
Y
Y
Y
Y
N
Unknown
N
Meets All NDWAC
Requirements
N
Y
Y
Y
Y
N
Y
Y
Meets
Retrievability
X
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source has been withdrawn; it is no
longer available online.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 29 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
83
84
95
87
88
89
91
90
94
Data Source Name
Guidelines for Canadian Drinking
Water Quality (CADW): Summary
of Guidelines
Guidelines for Canadian Drinking
Water Quality (CADW):
Supporting Documentation
Hazardous Substances Data Bank
(HSDB)
Health Advisories (HA) Summary
Tables - EPA
Health Advisory Documents
Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS
Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA
Healthlnsite
High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
X
X
Meets
Relevance
X
X
X
X
X
X
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
data elements (ADI, NO(A)EL) from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements (RfDs) from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
Meets
Redundancy
X
X
X
X
X
X
X
X
X
51 =
H
•0 Q.
fli X
Q: UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Y
Y
Y
Y
Y
Y
N
N
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
N
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
The list of contaminants in HSDB is
retrievable. The data are not formatted
for automated retrieval. The HSDB is a
unique and exceptional source and is
included to supplement the CCL
Universe.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 30 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
93
92
100
101
102
103
98
270
Data Source Name
High Production Volume (HPV)
Chemical List
Human Exposure Database
System (HEDS)
Idaho Toxic and Hazardous
Substances - Idaho Division of
Building Safety
Incidence and Prevalence
Database (IPD) - Timely Data
Resources
Indirect Additives Database
Infectious Disease Information
Information Collection Rule (ICR)
Federal Database
Information System for Hazardous
Organics in Water
Assessment Factor Evaluation
3 | Z
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This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
information that is related to potential
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
>*
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X
X
X
X
X
X
X
=" e
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1 =
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a: LU
This source is not redundant.
This source is not redundant.
This source is redundant with OSHA
PELs (source 234), which is a more
comprehensive source.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
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ki
*• E
o
O
X
X
X
X
X
X
X
"5
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£ 01
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1 31
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Y
N
Unknown
N
Y
N
Y
Unknown
O
II
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Y
Y
Y
Y
Y
Y
Y
N
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-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
108
104
204
96
97
99
43
Data Source Name
Integrated Risk Information
System (IRIS)
Integrated Taxonomy Information
System
International Agency for Research
on Cancer (IARC) - Summaries
and Evaluations
International Agency for Research
on Cancer (IARC) Monographs
International Bibliographic
Information on Dietary
Supplements (IBIDS)-NIH
International Chemical Safety
Cards (ICSCs) - 1 PCS/WHO/I LO
International Cosmetic Legal and
Regulatory Database - The
Cosmetic, Toiletry, and Fragrance
Association (CTFA)
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
X
Meets
Relevance
X
X
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
>• c
Q rr
H
•0 Q.
fli X
Q: UJ
The toxicological data for this
source are available in tabular
format from ITER (#110) and RAIS-
Health Effects (#178). Hence there
is some overlap and redundancy,
but each also provide additional
information not available elsewhere.
This source is not redundant.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
Documentation of
Peer Review
Y
Y
Y
Y
Y
Y
N
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
N
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source contains monographs that
were not formatted for automated
retrieval. However, the toxicological data
from this source have been compiled for
electronic retrieval in ITER, and were
obtained from there. IRIS monographs
were used to confirm the
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
The monographic information in this
source is not retrievable; however, the
list of contaminants and their cancer
groups is retrievable and will be used for
the CCL Universe. IARC is a unique and
exceptional source and is included to
supplement the CCL U
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
Page 32 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
106
109
110
105
107
111
112
113
264
Data Source Name
International Pharmaceutical
Abstracts (I PA)
International Register of Potentially
Toxic Chemicals (IRPTC PC) -
Data Profiles - UNEP Chemicals
International Toxicity Estimates for
Risk (ITER) Database
INTOX Databank - IPCS
IPCS/EC Evaluation of Antidote
Series
Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - 2001 Inventory
of Pesticide Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - Monographs of
Toxicological Endpoints
Label Review Manual
Assessment Factor Evaluation
3 | Z
<» 01 3
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1 %"-
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X
X
8
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d) 5
1 5
^&
X
X
X
X
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
>*
u
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X
X
X
X
X
X
X
=" e
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1 =
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fli X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant with IARC
Summaries and Evaluations.
INTOX is a subscription source and
IARC is independently and publicly
available.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
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ki
*• E
o
O
X
X
X
X
X
X
X
X
X
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N
Y
Y
Y
Y
Y
Y
Y
Unknown
O
II
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M
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U_
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Y
Y
Y
Y
Y
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Y
Y
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-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
114
115
286
116
124
117
278
118
119
Data Source Name
Laboratory Chemical Safety
Summaries (LCSS) - Howard
Hughes Medical Institute and
National Academy of Science
List of Bacterial Names with
Standing in Nomenclature
Mallinckrodt Baker, Inc., Material
Safety Data Sheets
Master Summary Table for HPV
Chemical Hazard Data Availability
Study
Material Safety Data Sheets
(MSDS)
Mediscover
MEDLINE
Michigan State Ribosomal
Database Project
MicrobeLibrary
Assessment Factor Evaluation
3 | Z
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This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
environmental fate data, that may be
used as an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
a list that is related to occurrence.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
>*
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X
X
X
X
X
X
X
X
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1 =
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This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of the HPV
Chemical List (source 93) and
CUS/IUR (source 33).
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
X
X
"5
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1 31
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Y
N
Unknown
N
Y
Y
N
Y
Y
O
II
Q 1
M
fCT
U_
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Y
Y
N
Y
Y
Y
Y
Y
Y
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-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
120
121
122
239
125
127
126
135
Data Source Name
Microbiology Abstracts, Section B:
Bacteriology - Cambridge
Scientific Abstracts
MicrobioNet
Morbidity and Mortality Weekly
Report (MMWR) Surveillance for
Waterborne-Disease Outbreaks
Multicase
Municipal Water Use Database -
Environment Canada
National Ambulatory Medical Care
Survey (NAMCS)
National Animal Health Reporting
System (NAHRS)
National Cancer Institute
Database of 3 Dimensional
Chemical Structures (NCI-3D)
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
if
if
"- UJ
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source does not meet relevance
criteria because it contains only
information on microbial contaminants.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
Meets
Redundancy
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is redundant with
FoodNet (source 74).
This source is redundant, as it is the
same as the Case model (source
238).
This source is not redundant.
This source is redundant, as it is
wholly available as part of IPD
(source 101).
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
N
Y
Y
Unknown
Unknown
Y
Unknown
Unknown
Meets All NDWAC
Requirements
y
Y
Y
N
Y
Y
Y
Y
Meets
Retrievability
X
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
Page 35 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
136
137
233
129
139
141
140
Data Source Name
National Drinking Water
Contaminant Occurrence
Database (NCOD) - 6-Year Data
National Drinking Water
Contaminant Occurrence
Database (NCOD) - Round 1&2
National Drinking Water
Contaminant Occurrence
Database (NCOD) - Unregulated
Contaminant Monitoring Rule
(UCMR)
National Environmental Data Index
(NEDI)
National Health and Nutrition
Examination Survey (NHANES)
National Hospital Discharge
Survey (NHDS)
National Human Adipose Tissue
Survey (NHATS)
Assessment Factor Evaluation
3 | Z
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This source does not meet relevance
criteria because it contains only
information for regulated contaminants.
This source is considered relevant for
the CCL Universe because it contains
measurements of unregulated
contaminants in drinking water,
demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
drinking water, demonstrating
occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
either the blood or urine, providing an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
information on prescribed medications.
These data might be used as a source
of information on potential occurrence
of Pharmaceuticals.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
human adipose tissue, providing an
indicator of occurrence.
>*
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X
X
X
X
X
X
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1 =
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This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of IPD
(source 101).
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
Y
Y
N
N
Y
Y
Y
O
II
Q 1
M
fCT
U_
s
Y
Y
Y
Y
Y
Y
Y
>:
to !5
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X
X
X
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-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
249
144
143
142
145
130
131
146
Data Source Name
National Human Exposure
Assessment Survey (NHEXAS)
National Inorganics and
Radionuclides Survey (NIRS)
National Institute for Occupational
Safety and Health (NIOSH) - Index
of Occupational Health Guidelines
for Chemical Hazards
National Institute of Enviornmental
Health Sciences (NIEHS)
Reproductive Toxicology Group
National Nosocomial Infections
Surveillance System (NNIS)
National Notifiable Diseases
Surveillance System
National Notifiable Diseases
Surveillance System (Australia)
National Occupational Exposure
Survey (NOES)
Assessment Factor Evaluation
3 | Z
<» 01 3
%$ %
1 %"-
<
X
8
« C
a) 5
1 5
^&
X
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information that is related to potential
exposure.
>*
u
J» ra
il
^•9
OL
X
X
X
X
X
X
X
=" e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is redundant, as it is
wholly available as part of HEDS
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
Y
Y
Y
Y
Y
Y
Unknown
Y
O
II
Q 1
M
fCT
U_
s
Y
Y
Y
Y
Y
Y
Y
Y
>:
to !5
a! «
1 5
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£
X
X
X
X
S? c
•— o
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a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
261
128
132
147
148
149
133
150
Data Source Name
National Pesticide Information
Retrieval System
National Pesticide Use Database
National Reconnaissance of
Emerging Contaminants (NREC) -
USGS Toxic Substances
Hydrology Program
National Research Council (NRC)
Publications
National Sanitary Foundation
(NSF) - Additives Standards 60
National Sediment Inventory (NSI)
National Stream Quality
Accounting Network (NASQAN)
National Toxicology Program
(NTP) Health and Safety Profiles
Assessment Factor Evaluation
3 | Z
<» 01 3
%$ %
1 %"-
<
X
X
8
« c
d) 5
1 5
^&
X
X
X
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on pesticide use, an
indicator of potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on health effects standards
for drinking water.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
sediments (which can contribute
contaminants to drinking water), and
can indicate potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
>*
u
J» ra
il
^•9
OL
X
X
X
X
X
X
>• e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is redundant with the
Pesticide Data Submitters' List, the
Pesticide Product Information
Database, and the Pesticide
Tolerance Index.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant with
NAWQA.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
Unknown
Unknown
Y
Y
Y
N
Y
Y
O
II
Q 1
M
fCT
U_
s
Y
Y
Y
Y
Y
Y
Y
Y
>:
to !5
a! «
1 5
S i
£
X
X
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
248
151
134
279
155
244
156
287
Data Source Name
National Toxicology Program
(NTP) Studies
National Water Information
System (NWIS Web)
National Water Quality
Assessment (NAWQA)
NIOSHTIC
Office International des Epizooties
(OIE) Handistatusll
Office Internationales Epizooties
Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact
Sheets
Oil and Hazardous
Materials/Technical Assistance
Data System
Assessment Factor Evaluation
3 | Z
<» 01 3
%$ %
1 %"-
<
X
X
8
« c
d) 5
1 5
^&
X
x
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
environmental fate data, that may be
used as an indicator of potential
occurrence.
>*
u
£ a
Jl
^11
OL
X
X
X
X
X
X
>• e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is not redundant.
This source is redundant with
NAWQA.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is identical to Office
International des Epizooties (OIE)
Handistatus II (source 155).
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
x
X
X
X
"5
H
£ 01
o *
1 31
r
Y
y
Y
Unknown
N
Unknown
N
Unknown
O
II
a i
M
fCT
U_
s
Y
Y
Y
Y
N
N
Y
N
>:
to !5
a! «
1 5
S i
£
x
X
X
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
237
152
234
163
158
161
160
159
Data Source Name
Oncologic
Organisation for Economic Co-
operation and Development
(OECD) Integrated HPV Database
OSHA 1988 Permissible Exposure
Limits (PELs)
Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support
Working Group
Pan American Health Organization
(PAHO) Communicable Disease
Permit Compliance System (PCS)
Database
Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)
Pesticide Action Network (PAN)
Assessment Factor Evaluation
3 | Z
<» 01 3
%$ %
1 %"-
<
X
8
« C
a) 5
1 5
^&
X
X
X
X
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
This source is considered relevant for
the CCL Universe because it is a list of
HPV chemicals, which may indicate
possible occurrence. It also contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on discharge of waste to
rivers, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it could be
a source of information on persistence,
providing an indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
health effects data.
>*
u
J» ra
il
^•9
OL
X
X
X
X
X
X
X
X
>• e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
Unknown
Y
Y
N
Unknown
Y
N
N
O
II
Q 1
M
fCT
U_
s
N
Y
Y
Y
Y
Y
Y
Y
>:
to !5
a! «
1 5
S i
£
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
265
162
266
257
262
168
267
268
269
259
Data Source Name
Pesticide Data Program
Pesticide Data Sheets (PDS) -
WHO, FAO
Pesticide Data Submitters List
(PDSL)
Pesticide Ecotoxicity Database
Pesticide Handler Exposure
Database
Pesticide Product Information
System (PPIS)
Pesticide Product Label System
(PPLS)
Pesticide Products Databases
Pesticide Tolerance Index System
(TISInfo)
Pesticides Ground and Surface
Water Incident Database
Assessment Factor Evaluation
Meets All
ssessment
Factors
<
X
Meets
Relevance
X
X
X
X
X
X
X
§1
1 i
~Sj "5.
nf X
"- UJ
This source is considered relevant for
the CCL Universe because it contains
measurements of pesticide residues,
an indicator of potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source is considered relevant for
the CCL Universe because it contains
information on human exposure to
pesticides.
This source is considered relevant for
the CCL Universe because it contains
an indicator of possible health effects.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of contaminants with possible
health effects.
This source is considered relevant for
the CCL Universe because it contains
information on pesticide exposure
tolerances.
This source is considered relevant for
the CCL Universe because it is being
designed to contain information on
pesticide occurrence in water, an
indicator of occurrence.
Meets
edundancy
or
X
X
X
X
X
X
X
"fl> X
Q: UJ
This source is not redundant.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.
This source is not redundant.
This source is not redundant.
This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.
This source is not redundant.
This source is redundant with
FIFRA.
This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.
This source has been withdrawn; it
is no longer available online.
Meets
mpleteness
o
O
X
X
X
X
X
X
X
X
X
umentation of
eer Review
r
Unknown
Y
Unknown
Y
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
ts All NDWAC
squire me nts
£ n:
Y
Y
Y
Y
Y
Y
Y
Y
Y
N
Meets
;trievability
OL
X
X
X
S? c
1= O
5 ra
£uj
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source has been withdrawn; it is no
longer available online.
Page 41 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
260
164
280
165
166
167
169
170
157
Data Source Name
Pesticides in Ground and Surface
Water Database
Pesticides Pilot Monitoring
Program - USGS/EPA
Plant Toxicity Data
Poisons Information Monographs
(PIMs)-IPCS, CCOHS
POLLUAB - Pollution Abstracts
Pollution Prevention Research and
Development Database -
EnviroNET Australia
Preliminary Remediation Goals
(PRGs) - EPA Region 9
Priority Substances Assessment
Program - Health Canada
Priority-based Assessment of
Food Additives (PAFA) Database
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
Meets
Relevance
X
X
X
X
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it is being
designed to contain information on
pesticide occurrence in water, an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
information on plant toxicity.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
Meets
Redundancy
X
X
X
X
X
>• c
Q rr
H
•0 Q.
fli X
Q: UJ
This source has been withdrawn; it
is no longer available online.
This source is not redundant.
This source is redundant with
ECOTOX (source 57).
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is not redundant.
This source is not redundant.
The relevant data in this source are
redundant with ITER and IRIS.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
Documentation of
Peer Review
Unknown
Y
Unknown
Y
Y
Unknown
Y
Y
Y
Meets All NDWAC
Requirements
N
Y
N
Y
Y
N
Y
Y
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source has been withdrawn; it is no
longer available online.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
Page 42 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
171
172
173
180
176
275
179
177
178
Data Source Name
Program for Monitoring Emerging
Disease (ProMED)
PubMed
PulseNet: The National Molecular
Subtyping Network for Food borne
Disease Surveillance
Registry of Toxic Effects of
Chemical Substances (RTECS)
Reregistration Eligibility Decision
Documents (REDDs) - EPA OPP
Resource Conservation and
Recovery Information System
Rijksinstituut voor
Volksgesondheid en Milieu (RIVM)
Maximum Permissible Risks
(MPRs) Report
Risk Assessment Information
System (RAIS) - Department of
Energy - Chemical Factors
Risk Assessment Information
System (RAIS) - Department of
Energy - Health Effects Data
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
X
Meets
Relevance
X
X
X
X
X
if
if
"- UJ
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
radioactive half-life data, providing an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
Meets
Redundancy
X
X
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Y
Y
Y
Y
Unknown
Y
Y
Y
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
N
Y
Y
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
Page 43 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
175
281
232
182
183
189
190
191
Data Source Name
Risk Based Concentrations
(RBCs) - EPA Region 3
RISKLINE
Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for
Economic Co-operation and
Development (OECD)
SOLV-DB
Source Ranking Database (3RD)
State Drinking Water Data Sets
State of California EPA Chemicals
Known to the State to Cause
Cancer or Reproductive Toxicity
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
Meets
Relevance
X
X
X
X
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements (LDx, NO(A)EL) from
toxicological studies.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is considered relevant for
the CCL Universe because it has
elements that may indicate possible
occurrence and/or possible health
effects.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
Most data are available for regulated
contaminants. Some data are
available for unregulated
contaminants.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
Meets
Redundancy
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
The relevant data in this source are
redundant with ITER and IRIS.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is partially redundant,
as it is mostly available as part of
NCOD - Six Year (source 136).
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Unknown
Unknown
Y
N
Y
N
Y
Meets All NDWAC
Requirements
Y
N
Y
Y
Y
Y
Y
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source meets retrievability criteria
because it is in tabular format.
Page 44 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
192
193
194
195
196
197
198
199
Data Source Name
State of New Jersey Hazardous
Substances Right to Know Fact
Sheets
STN - CA/CA Plus File - Chemical
Abstracts
STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STN - DETHERM
STN - Handbook Of Data on
Organic Compounds Database
(HODOC)
STN - Merck Index Online (MRCK)
STN-NUMERIGUIDE
STN - Toxicology Center
(TOXCENTER)
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
X
if
if
"- UJ
This source is considered relevant for
the CCL Universe because it contains
information on carcinogenicity and
potential health effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list related to health effects or
occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
N
Y
Meets
Retrievability
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 45 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
200
201
202
271
203
181
251
254
Data Source Name
STN-ZREGISTRY
STN and STN Easy - Scientific
and Technical Information Network
STORET - STORage and
RETrieval
Structure and Nomenclature
Search System
Substance Registry System (SRS)
Superfund Contract Laboratory
Program (SCLP) Water/Soil Data
Syracuse Research Corporation
(SRC) - BIODEG
Syracuse Research Corporation
(SRC) - BIOLOG
Assessment Factor Evaluation
Meets All
Assessment
Factors
X
X
Meets
Relevance
X
X
X
X
if
if
"- UJ
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
X
51 =
H
•0 Q.
fli X
Q: UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
Documentation of
Peer Review
Unknown
Unknown
N
Unknown
N
Y
Y
Y
Meets All NDWAC
Requirements
Y
N
Y
N
Y
Y
Y
Y
Meets
Retrievability
X
X
S? c
1= O
1 1
1 a.
& UJ
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
SRS is retrievable by EPA. SRS is
EPA's registry and provides the
identifying EPA data standards for the
CCL substances.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 46 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
252
184
253
185
186
187
282
207
Data Source Name
Syracuse Research Corporation
(SRC) - CHEMFATE
Syracuse Research Corporation
(SRC) - Chemical Pointer File
Syracuse Research Corporation
(SRC) - DATALOG
Syracuse Research Corporation
(SRC) - Environmental Fate
Databases (EFDB)
Syracuse Research Corporation
(SRC) - Physical Property
Database (PHYSPROP)
Syracuse Research Corporation
(SRC) - Simplified Molecular Input
Entry System (SMILECAS
Database)
Terrestrial Toxicity Information
The Institute for Genomics
Research (TIGR) Microbial
Database
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
if
if
"- UJ
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant. It is
available as a suite of data sources:
BIOLOG, BIODEG, CHEMFATE,
and DATALOG.
This source is not redundant.
This source is redundant with NCI-
3D (source 135).
This source is redundant with
ECOTOX (source 57).
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
Documentation of
Peer Review
Y
Unknown
Y
Unknown
Unknown
Unknown
Unknown
Y
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
N
Y
Meets
Retrievability
X
X
X
X
X
S? c
1= O
1 1
1 g.
& UJ
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source meets retrievability criteria
because it is in tabular format.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
Page 47 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
205
138
153
154
240
206
212
208
250
Data Source Name
The Manual of Clinical
Microbiology, 7th edition.
The National Environmental
Methods Index (NEMI)
The Office of Ground Water and
Drinking Water (OGWDW) -
Consumer Fact Sheets
The Office of Ground Water and
Drinking Water (OGWDW) -
Technical Fact Sheets
The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)
The Prokaryotes: A handbook on
the biology of bacteria:
Ecophysiology, Isolation,
Identification, and Applications
The Toxics Release Inventory
(TRI)
TOMES PLUS, MICROMEDEX -
Thomson-Micromedex
Total Exposure Assessment
Methodology Study (TEAM)
Assessment Factor Evaluation
5 1 B
1 s£
o "> "
s 8"-
<
X
s
« c
% |
g Si
£
X
X
X
X
§1
1 i
~Sj o.
nf X
"- UJ
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it contains only
information for regulated contaminants.
This source does not meet relevance
criteria because it contains only
information for regulated contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on chemical releases,
which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
information on potential health effects.
>*
o
ll
*ti
OL
X
X
X
X
X
X
X
X
X
•o ™
"fl> X
Q: UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
eets
leteness
Sf
o
O
X
X
X
X
X
X
X
X
X
sntation of
Review
ll
r
Y
Y
Y
Y
Unknown
Y
Y
Y
Unknown
til NDWAC
rements
1 3
fCT
u_
s
Y
Y
Y
Y
Y
Y
Y
Y
Y
>:
to !5
1 i
si
&
X
S? c
1= O
5C
£uj
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 48 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
288
209
211
284
213
214
216
217
Data Source Name
Toxic Substances Control Act
(TSCA) List
Toxicity Criteria Database -
California Office of Environmental
Health Hazard Assessment
(OEHHA)
TOXLINE
TSCA Plant and Production
TSCATS - Toxic Substances
Control Act Test Submissions
UCM - Round 2 (SDWIS/FED) -
Unregulated Contaminant
Monitoring
University of Akron Chemical
Database
University of Maryland - Partial List
of Acute Toxins/Partial List of
Teratogens
Assessment Factor Evaluation
3 | 2!
<» 01 3
%$ %
1 %"-
<
X
X
X
8
« c
d) 5
1 5
^&
X
X
X
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals with known
toxicity/health effects.
>*
u
£ a
Jl
^11
OL
X
X
X
X
X
X
X
=" e
c o
n '•=
1 =
1 "
•o a-
fli X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of NCOD -
Round 1&2 (source 137).
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
X
X
"5
H
£ 01
o *
1 31
r
Unknown
Y
Y
Unknown
Y
Y
Unknown
Unknown
O
II
Q 1
M
fCT
U_
s
Y
Y
Y
N
Y
Y
N
Y
>:
to !5
a! «
1 5
S i
£
X
X
X
X
S? c
•— o
!a «
a B
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
215
219
220
273
221
222
223
Data Source Name
University of Minnesota
Biocatalysis & Biodegradation
Database (UM-BBD)
Unregulated Contaminant
Information System (URCIS)
US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets
US EPA Civil Enforcement Docket
Victorian Infectious Diseases
Reference Laboratory (VIDRL)
Voluntary Cosmetic Registration
Program Database (VCRP)
Wastelnfo - AEA Technology
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
X
§1
1 2
& ra
~S a.
nt x
"- UJ
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
£§
H
l|
"fl> X
o: uj
This source is not redundant.
This source is redundant, as it was
converted into NCOD Round 1
database, so URCIS is no longer
needed.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
Documentation of
Peer Review
Unknown
Y
Y
Unknown
Unknown
Unknown
N
Meets All NDWAC
Requirements
Y
Y
Y
Y
N
N
N
Meets
Retrievability
X
S? c
•— o
•o '•%
„ ™
oi ra
£ °-
£m
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 50 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
228
229
224
225
236
226
227
Data Source Name
Water Environment Research
Foundation (WERF) Microsheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets
Water Resources Abstracts -
Cambridge Scientific Abstracts
Water Resources Worldwide
WATERLIT
WATERNET - American Water
Works Association
Weekly Epidemiological Record
(WER)
Assessment Factor Evaluation
Meets All
Assessment
Factors
Meets
Relevance
X
if
~Sj "5.
nf X
"- UJ
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy
X
X
X
X
X
X
X
51 =
11
•0 Q.
0} X
It UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
Documentation of
Peer Review
Y
Y
N
N
Unknown
N
Y
Meets All NDWAC
Requirements
Y
Y
Y
N
N
Y
Y
Meets
Retrievability
S? c
1= O
11
0) TO
- *•
& i±i
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 51 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 1. CCL 3 All Data Sources - Assessment Table
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID
85
86
40
230
Data Source Name
WHO Guidelines for Drinking
Water Quality: Chemical Aspects:
Index of Chemicals
WHO Guidelines for Drinking
Water Quality: Summary Tables
WHO Recommended
Classification of Pesticides by
Hazard (CPH)
World Health Organization -
Information Products Catalogue
Assessment Factor Evaluation
3 | Z
<» 01 3
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1 %"-
<
X
8
« C
a) 5
1 5
^&
X
X
X
M
g "
3J ra
ai a.
£ *
01 LU
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly to
CCL, and its data elements are
inconsistently presented.
>*
u
J» ra
il
^•9
OL
X
X
X
X
>• e
c o
n '•=
1 =
1 "
•o a-
0) X
a: LU
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
to
to
HI
<3 §
ki
*• E
o
O
X
X
X
X
"5
H
£ 01
£ *
i 31
r
Y
Y
Y
Y
O
II
Q 1
M
fCT
U_
s
Y
Y
Y
Y
>:
to !5
a! «
1 5
S i
£
X
S? c
1= O
!a «
a B
ai ro
- &
£ Lll
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because, with the exception of
the classifications, it is not formatted for
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Page 52 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID Data Source Name
12 ATSDR CERCLA Priority List
123 ATSDR Minimal Risk Levels (MRLs)
Chemical Toxicity Database - Ministry
of Health and Welfare, Japan
Chemical Update System/Inventory
Update Rule (CUS/IUR)
jCumulative Estimated Daily
26 Intake/Acceptable Daily Intake
(CEDI/ADI) Database
Database of Sources of
46 Environmental Releases of Dioxin-
Like Compounds in the United States
Distributed Structure Searchable
53 JToxicity Public Database Network
(DSSTox)
! Everything Added to Food in the
United States (EAFUS) Database
9ftQ Federal Insecticide, Fungicide, and
Rodenticide Act (FIFRA) List
iGenerally Regarded As Safe (GRAS)
Substance List
Guidelines for Canadian Drinking
83 Water Quality (CADW): Summary of
Guidelines
^Hazardous Substances Data Bank
yS (HSDB)
Health Advisories (HA) Summary
Tables -EPA
p.. High Production Volume (HPV)
Chemical List
102 Indirect Additives Database
Proprietor
Agency for Toxic Substances and
Disease Registry
Agency for Toxic Substances and
Disease Registry
Ministry of Health and Welfare,
Japan
EPA
FDA - Center for Food Safety and
Applied Nutrition
EPA, ORD
EPA
FDA - Center for Food Safety and
Applied Nutrition; CFSAN, Office
of Food Additive Safety
EPA
FDA - Center for Food Safety and
Applied Nutrition
Health Canada
National Library of Medicine, NIH
EPA Office of Wat er; OST
EPA's Office of Pollution
Prevention and Toxics (OPPT)
FDA - Center for Food Safety and
Applied Nutrition; CFSAN, Office
of Food Additive Safety
Assessment Factor Evaluation
Relevance
Demonstrated
Occurrence?
N
N
N
N
N
N
N
N
N
N
N
N
N
N
Potential
Occurrence?
Y
N
N
Y
N
Y
N
N
N
N
Y
N
Y
Y
Demonstrated
Health Effects?
N
Y
Y
N
Y
N
Y
N
N
Y
Y
Y
N
N
Potential
Health Effects?
Y
N
N
N
N
N
Y
Y
Y
N
N
N
N
N
This source is considered relevant for the CCL
Universe because the basis for developing this list
is ATSDR's prioritization of chemicals found at
NPL sites and that ATSDR believes may pose a
human health risk.
This source is considered relevant for the CCL
Universe because it contains data elements (MRL)
derived from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements
(LD50, NOEL) from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
production volume, which may indicate potential
occurrence.
This source is considered relevant for the CCL
Universe because it contains health effects data.
This source is considered relevant for the CCL
Universe because it contains information on air
emissions, which may indicate potential
occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to their toxicity/health effects.
This source is considered relevant for the CCL
Universe because it contains data elements (ADI,
NO(A)EL)from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it is a list and contains
information on production volume, which may
indicate potential occurrence.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to potential exposure.
Redundancy
This source is not redundant.
These data are also represented in
the ATSDR Toxicological Profiles;
however, these data are tabular
while the Profiles are monographic.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Completeness
Documentation of
Peer Review
Y
Y
Y
Unknown
Y
Y
Unknown
Y
Unknown
Y
Y
Y
Y
Y
Y
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
1 1 §
I ! I
1 I I
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular/Monogr criteria because the relevant
aphic data can be extracted in
I | tabular format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
I jThis source meets retrievability
Tabular N criteria because it is in tabular
! ! format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
-.. , , i .. i criteria because the relevant
Tabular | N | data can be extracted in
i i tabular format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
... i Unknow i criteria because it is accessible
Unknown | n | through EpA,s Substance
Registry System.
Monographic This source meets retrievability
(can be M criteria because the relevant
extracted in a data can be extracted in
tabular format) tabular format.
This source meets retrievability
Tabular N criteria because it is in tabular
The list of contaminants in
HSDB is retrievable. The data
are not formatted for
Monographic i N i Automated retrieval. The
u ^ 1 1 HSDB is a unique and
exceptional source and is
included to supplement the
CCL Universe.
This source meets retrievability
Tabular N criteria because it is in tabular
! ! format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
Page 53 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identif
ID Data Source Name
12 ATSDR CERCLA Priority List
123 ATSDR Minimal Risk Levels (MRLs)
Chemical Toxicity Database - Ministry
of Health and Welfare, Japan
Chemical Update System/Inventory
Update Rule (CUS/IUR)
Cumulative Estimated Daily
26 Intake/Acceptable Daily Intake
(CEDI/ADI) Database
Database of Sources of
46 Environmental Releases of Dioxin-
Like Compounds in the United States
Distributed Structure Searchable
53 JToxicity Public Database Network
(DSSTox)
! Everything Added to Food in the
United States (EAFUS) Database
_„_ Federal Insecticide, Fungicide, and
Rodenticide Act (FIFRA) List
81 Generally Regarded As Safe (GRAS)
Substance List
Guidelines for Canadian Drinking
83 Water Quality (CADW): Summary of
Guidelines
Hazardous Substances Data Bank
(HSDB)
Health Advisories (HA) Summary
Tables -EPA
p.. High Production Volume (HPV)
Chemical List
102 Indirect Additives Database
ill! I !i
5 s a o ! £
gill
v I..!.. ... ! CERCLA
Y ! N ! N N 313 ! Contaminants
N | N | N N 165 Chemicals
N | N | N N 222 HPV Chemicals
N ! N ! N N 13753 ! _JSC*
! | Chemcials
N N ^ N N 111ft Food Contact
I Substances
N N | N N 168 Dioxin-like
N | Y | N N 1557 Chemicals
Y | N | N N 3284 Food Additives
Y | N | N N 114 Food Additives
N ! N ! Y N 157 ! che™cals,
I i Microbes
N | Y | N N 4688 Chemicals
! Chemicals,
N N | Y N 216 Inorganics,
! ! Microbes
Y | N | N N 2765 HPV Chemicals
N N | N N 3372 ™^
Type of Data Elements
Name, CASRN, rank
Name, CASRN, MRL (chronic, intermediate, acute)
Name, CASRN, formula, LD50, NOEL, mutation data
Production Volume
Name, CASRN, ADI, CEDI, CUM DC
Emmissions, Release to Air
TD50
Name, CASRN, status of toxicology information
Unknown
Notifier, Intended Use, Basis, Receipt Date, Closure Date
ADI, AO, CR, Critical Effect, DCF, Dose, Duration, Environmental Fate,
Guideline,
Half-life 11/2 (days), IMAC (mg/L), LDx, MAC, NO(A)EL, Occurrence,
Physical/Chemical, Production/Use, Route
Name, CASRN, synonyms, ID numbers, Use, Production, IARC cancer
class, EPA cancer group, Evidence for carcinogenicity, Critical effect,
Mutagenicity, Irritation data, Susceptible populations, Body burden,
Occupational exposure, MTD, LDx, Estimated daily i
Name, CASRN, CR, DWA, DWEL, HA (1d, 10d, lifetime), MCL, MCLG,
RfD, SDWR
Name, CASRN, HPV Challenge status
CFSAN Name, CASRN, Regulation Number
Potential Update
Frequency
! Biennially
| Biennially
! As Needed
| Every 4 years
| As Needed
| NA
i As needed
| As Needed
| Variable
I Annually
I Quarterly
| Biennially
i Every 4 years
| As Needed
Last Updated
(per last check)
2003
2003
2002
2002
2002
1995
2004
2004
2004
2003
2003
2004
2002
2003
Page 54 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID Data Source Name
.nft Integrated Risk Information System
International Agency for Research on
Cancer (IARC) Monographs
, , _ I International Toxicity Estimates for
Risk (ITER) Database
Joint Meeting On Pesticide Residues
112 |(JMPR)- 2001 Inventory of Pesticide
Evaluations
National Drinking Water Contaminant
137 Occurrence Database (NCOD) -
Round 1&2
National Drinking Water Contaminant
233 Occurrence Database (NCOD) -
Unregulated Contaminant Monitoring
Rule(UCMR)
... National Inorganics and
Radionuclides Survey (NIRS)
128 National Pesticide Use Database
National Reconnaissance of
..„_! Emerging Contaminants (NREC)-
USGS Toxic Substances Hydrology
Program
INational Toxicology Program (NTP)
jStudies
.„. National Water Quality Assessment
(NAWQA)
Proprietor
EPA Office of Research and
Development; ORD, National
Center for Environmental
Assessment
International Agency for Research
on Cancer
TERA - Toxicology Excellence for
Risk Assessment /NLM
World Health Organization, Food
and Agriculture Organization
EPA Office of Ground Water and
Drinking Water
EPA Office of Ground Water and
Drinking Water
EPA OGWDW; The Cadmus
Group, Inc.
National Center for Food and
Agricultural Policy (NCFAP)
USGS
National Toxicology Program; NIH
USGS
Assessment Factor Evaluation
Relevance
Demonstrated
Occurrence?
N
N
N
N
Y
Y
Y
N
Y
N
Y
Potential
Occurrence?
N
N
N
N
N
N
N
Y
N
N
N
Demonstrated
Health Effects?
Y
Y
Y
Y
N
N
N
N
N
Y
N
Potential
Health Effects?
N
N
N
N
N
N
N
N
N
N
N
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements
directly from and derived from toxicological
studies.
This source is considered relevant for the CCL
Universe because it contains data elements
derived from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains measurements of
unregulated contaminants in drinking water,
demonstrating occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in drinking water, demonstrating
occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating occurrence.
This source is considered relevant for the CCL
Universe because it contains information on
pesticide use, an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating occurrence.
Redundancy
The toxicological data for this
source are available in tabular
Format from ITER (#110) and RAIS-
Health Effects (#178). Hence there
is some overlap and redundancy,
but each also provide additional
information not available
elsewhere.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Completeness
Documentation of
Peer Review
Y
Y
Y
Y
Y
N
Y
Unknown
Y
Y
Y
O J2
•z. E
if
E
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
1 1 §
I | f
Q tn
This source contains
monographs that were not
formatted for automated
retrieval. However, the
.. , . i .. i toxicological datafrom this
Monographic | N | source have been compHed for
electronic retrieval in ITER, and
were obtained from there. IRIS
monographs were used to
i i confirm the
The monographic information
in this source is not retrievable;
however, the list of
contaminants and their cancer
Monographic 1 N !gr°Up" 'lf ^^ f?d *"' ^
u ^ i i used for the CCL Universe.
IARC is a unique and
exceptional source and is
included to supplement the
CCLU
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
This source meets retrievability
Tabular N criteria because it is in tabular
This source meets retrievability
Tabular/ N criteria because USGS
Monographic provided the data directly to
EPA in a useable format.
This source does not meet
retrievability criteria because
the data are not formatted for
Monographic 1 Y 1 a"'°mated relrieval. NTP
i i studies provide unique and
exceptional data and are
included to supplement the
! ! CCL Universe.
This source meets retrievability
Tabular/ N criteria because USGS
Monographic provided the data directly to
EPA in a useable format.
Page 55 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identif
ID Data Source Name
.nft Integrated Risk Information System
International Agency for Research on
Cancer (IARC) Monographs
, , _ ! International Toxicity Estimates for
Risk (ITER) Database
Joint Meeting On Pesticide Residues
112 |(JMPR)- 2001 Inventory of Pesticide
Evaluations
National Drinking Water Contaminant
137 Occurrence Database (NCOD) -
Round 1&2
National Drinking Water Contaminant
233 Occurrence Database (NCOD) -
Unregulated Contaminant Monitoring
Rule(UCMR)
... National Inorganics and
Radionuclides Survey (NIRS)
128 National Pesticide Use Database
National Reconnaissance of
.„,,! Emerging Contaminants (NREC) -
USGS Toxic Substances Hydrology
Program
INational Toxicology Program (NTP)
jStudies
.„. National Water Quality Assessment
(NAWQA)
ill! I !i
5 s a o ! £
gill
N ! N j N i N 650 Chemicals
N | Y | N N 890 Carcinogens
N | N | N N 533 Chemicals
N | N | N N 240 Pesticides
! Unregulated
N | N | Y N 76 Chemicals,
! Microbes
N N | N N 23 ^emlc^?
N | N | N N 42 .
N ! N ! N i N 235 Pesticides
! Pharmaceuticals
N |N ! N ! N 123 |, Consumer Use
| Chemicals
N | N ! N ! N 715 Chemicals
! Nutrients,
N i N ! N N 224 i Pesticides,
i ! i VOCs
Type of Data Elements
Name, Synonyms, CASRN, RfC, RfD, SF(i,o), UR(i,o), NO(A)EL,
LO(A)EL, BMC/D, BMDL, Critical effect
Summary of Data Reported and Evaluation, Exposure data, Human
carcinogenicity data, Animal carcinogenicity data, Other relevant data,
Overall evaluation, Previous evaluations
Name, CASRN, Critical effect, Cancer risk, Slope factor, MRL, RfD, RfC
TC(A), TDI, RSC, RSD, LO(A)EL, NO(A)EL, TumCx, TumDx, TC05,
TC01 , TD05, Tl, TC, Risk Value, Basis
Name, CASRN, ADI
Drinking water occurrence concentrations
Drinking Water Occurrence Concentrations
Drinking Water Occurrence Concentrations
Name, Ibs Al applied, # States applied
Ambient Water Occurrence Concentrations, Min, Max Value
Name, Synonyms, CASRN, Formula, Structure, Categories of evidence
of carcinogenic activity, Statistical results
Occurrence Concentrations
Potential Update
Frequency
I As Needed
! As Needed
! As Needed
| As Needed
| As Needed
| As Needed
! None
I Every 5 years
! Annually
! Unknown
! As Needed
Last Updated
(per last check)
2003
2002
2003
2002
2002
2004
1986
1997
2000
2003
2002
Page 56 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identification
ID Data Source Name
™.|OSHA 1988 Permissible Exposure
Limits (PELs)
265 Pesticide Data Program
1fi. ! Pesticides Pilot Monitoring Program -
1b4 USGS/EPA
Risk Assessment Information System
177 (RAIS) - Department of Energy -
Chemical Factors
Risk Assessment Information System
178 (RAIS) - Department of Energy -
Health Effects Data
State of California EPA Chemicals
191 Known to the State to Cause Cancer
or Reproductive Toxicity
203 Substance Registry System (SRS)
„! ISyracuse Research Corporation
(SRC)-BIODEG
21 2 The Toxics Release Inventory (TRI)
288 Toxic Substances Control Act (TSCA)
List
Toxicity Criteria Database - California
209 Office of Environmental Health
Hazard Assessment (OEHHA)
jUniversity of Maryland - Partial List of
217 Acute Toxins/Partial List of
iTeratogens
86 WHO Guidelines for Drinking Water
Quality: Summary Tables
Proprietor
NIOSH
USDA
EPA Office of Ground Water and
Drinking Water and USGS
NAWQA
U.S. Department of Energy
U.S. Department of Energy
State of California
EPA
Syracuse Research Corporation
EPA
EPA
California Office of Environmental
Health Hazard Assessment
University of Maryland
World Health Organization
Assessment Factor Evaluation
Relevance
Demonstrated
Occurrence?
N
N
Y
N
N
N
N
N
N
N
N
N
N
Potential
Occurrence?
N
Y
N
Y
N
N
N
Y
Y
Y
N
N
N
Demonstrated
Health Effects?
Y
N
N
N
Y
N
N
N
N
N
Y
N
Y
Potential
Health Effects?
N
N
N
N
N
Y
N
N
N
N
N
Y
N
This source is considered relevant for the CCL
Universe because it contains inhalation exposure
limits, which may provide information on potential
health effects.
This source is considered relevant for the CCL
Universe because it contains measurements of
pesticide residues, an indicator of potential
occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating occurrence.
This source is considered relevant for the CCL
Universe because it contains radioactive half-life
data, providing an indicator of occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements
directly from and derived from toxicological
studies.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to their toxi city/health effects.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
that is related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains information on
persistence, that may be used as an indicator of
potential occurrence.
This source is considered relevant for the CCL
Universe because it contains information on
chemical releases, which may indicate potential
occurrence.
This source is considered relevant for the CCL
Universe because it is a list and contains
information on production volume, which may
indicate potential occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements
derived from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains a list of chemicals
with known toxi city/health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
Redundancy
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Completeness
Documentation of
Peer Review
Y
Unknown
Y
Y
Y
Y
N
Y
Y
Unknown
Y
Unknown
Y
O J2
•z. E
i
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
1 1 §
I | f
Q ] (0 ]
This source meets retrievability
Monographic N criteria because it is in tabular
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular/ .. criteria because the relevant
Monographic data can be extracted in
i i tabular format.
This source meets retrievability
Tabular/Monogr .. criteria because the relevant
aphic data can be extracted in
tabular format.
This source meets retrievability
Tabular/Monogr .. criteria because the relevant
aphic data can be extracted in
i i tabular format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
i i SRS is retrievable by EPA.
SRS is EPA's registry and
Tabular N provides the identifying EPA
data standards for the CCL
! ! substances.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Tabular N criteria because it is in tabular
format.
This source meets retrievability
Unknow criteria because it is accessible
n through EPA's Substance
Registry System.
This source meets retrievability
Tabular N criteria because it is in tabular
This source meets retrievability
Tabular N criteria because it is in tabular
! ! format.
This source meets retrievability
Tabular N criteria because it is in tabular
i i format.
Page 57 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 2. CCL 3 Universe of Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
* !
I r o P
i t^- ~ .£
I <- o 5 i |
ID i Data Source Name u> £ o fe £
i J 13 o o o
i » S 3 ^
! E m 0
i £ °
\ 0 Z
JOSHA 1988 Permissible Exposure ' | '
! Limits (PELs) !
265 Pesticide Data Program N j N | N N 219
,„. iPesticides Pilot Monitoring Program - !
164JUSGS/EPA N N i N N 177
Risk Assessment Information System j
177 (RAIS) -Department of Energy- N Y | N N 1498
Chemical Factors j
Risk Assessment Information System j
178 (RAIS)- Department of Energy- N j N | N N 1479
Health Effects Data |
State of California EPA Chemicals I
191 Known to the State to Cause Cancer Y | N | N | N 694
or Reproductive Toxicity j
203 Substance Registry System (SRS) N Y | Y N 83000
jSyracuse Research Corporation |
|(SRC)-BIODEG N Y | N N /W
212 The Toxics Release Inventory (TRI) N j N | N N 509
Toxic Substances Control Act (TSCA) „ M ^ M M
List |
Toxicity Criteria Database - California j
209 Office of Environmental Health N i N j N i N 262
Hazard Assessment (OEHHA) j
jUniversity of Maryland - Partial List of j
217 Acute Toxins/Partial List of Y! N JN N 2519
iTeratogens !
IVWO Guidelines for Drinking Water |
86 iQuality: Summary Tables N N | N N 137
Type of Contaminant
Detail
Occupational
Chemicals
Pesticides
Pesticides
Chemicals
Chemicals
Carcinogens
Chemicals,
Microbes
Chemicals
Chemicals
Industrial
Chemicals
Chemicals
Chemicals
Chemicals
Type of Data Elements
Name, CAS RN, OSHA PEL
Total Samples Analyzed, Samples with Residues Detected, Percent of
Samples with Detections, Different Pesticides Detected, Different
Residues Detected, Total Residue Detections, % of Samples with
Detects, Minimum Value Detected, ppm, Maximum Value Detected
Drinking Water Occurrence Concentrations
Name, CASRN, Absorption factor, beef transfer coefficient, BP, Soil to
Plant dry uptake, Soil to Plant wet uptake, Diffusivity in air, Diffusivity in
water, Fish bioaccumulation factor, Gl absorption factor, Gl absorption
fraction, Radioactive half life,
RfD (critical effect), RfC, Slope Factor, Unit Risk, Absorption Factor,
Cancer Class
Name, CASRN, Date added to list, Carcinogenicity and Reproductive
Toxicity
CAS RN, Classification, Molecular Formula, Molecular Weight,
Regulatory Resources, Other Sources, Group/Component, Related
Links
Name, CASRN, Biodegradation - aerobic, anaerobic, soil, sediment,
sewage, fresh water, seawater, other
Chemical releases to air, land, and water
Unknown
Critical effect, CAMCL, CAPHG, cancer risk, cancer groups, MADL,
NSRL, REL, slope factor, unit risk
Name
Name, GV, TDI, basis
Potential Update
Frequency
Unknown
Unknown
Finished
As Needed
As Needed
Annually
Unknown
Quarterly
Annually
As Needed
Not Updated
As Needed
Last Updated
(per last check)
Unknown
Unknown
2000
2003
2003
2004
2002
2004
2002
2003
1995
1998
Page 58 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
ource en i ica ion
ID
1
9
210
235
24
28
38
35
41
241
50
242
Data Source Name
10th Report on Carcinogens - NTP
Alternate Crops and Systems (ARS)
Pesticide Properties Database
ATSDR Internet HazDat - Site
Contaminant Query
ATSDR Toxicological Profiles
California Department of Pesticide
Regulation (CDPR)
Chemical Carcinogenesis Research
Information System (CCRIS)
Chemical Evaluation Search and
Retrieval (CESARS) - CCOHS
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)
Concise International Chemical
Assessment Documents (CICADs)
CrossFire BEILSTEIN
Derek
Dictionary of Substances and Their
Effects - Knovel
EC Water Directive
Proprietor
Department of Health and Human
Services - National Toxicology
Program
Alternate Crops & Systems
Laboratory, United States
Department of Agriculture
Agency for Toxic Substances and
Disease Registry
Agency for Toxic Sutstances and
the U.S. Department of Health
and Human Services (DHHS),
Centers for Disease Control
(CDC)
California Department of
Pesticide Regulation
National Library of Medicine; NIH;
developed and maintained by
NCI
Canadian Center for
Occupational Health and Safety
(CCOHS)
EPA Envirofacts Data
Warehouse and Applications
International Programme for
Chemical Safety, World Health
Organization, International
Labour Organisation, United
Nations Environment Programme
MDL Information Systems GmbH
(formerly known as BEILSTEIN
Informations systemme)
LHASA Limited
Knovel
European Community
Assessment Factor Evaluation
Relevance
1> ^;
c t
1 0
Q 0
N
N
N
N
N
N
N
N
N
N
N
N
_ 0)
® t
Q- S
O
N
Y
N
N
N
N
Y
N
Y
N
N
N
| H
^ u]
E =
°£
Y
N
Y
N
Y
Y
N
Y
N
N
Y
N
S
c LU
£ ^
0)
X
Y
N
N
N
N
N
N
N
Y
Y
N
N
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
persistence, that may be used as an indicator of
potential occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and information on
production, which may indicate potential
This source is considered relevant for the CCL
Universe because it contains a list of bioactive
compounds.
This source is considered relevant for the CCL
Universe because it contains the results of
carcinogenicity and mutagenicity studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
potential contaminant occurrence at superfund
sites.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it could be a source of
information on potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains regulatory limits for
contaminants in drinking water.
Redundancy
This source is not
'
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
Completeness
'o
c g
o ®
5 '1
3 0)
r
Y
Y
Unknown
Y
Y
Y
Y
Y
Y
Y
Unknown
Y
Unknown
u
S "*=
z E
« o-
8 o:
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
•£
o
Li-
IS
Monographic
Tabular
Tabular
Monographic
Text
Monographic
Monographic
Tabular
Monographic
Monographic
Model
Unknown
Legislation
c
o
(/)
N
N
N
N
N
Y
N
N
Y
Y
Y
No
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates. The source is only
available through a subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
Page 59 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
ID
1
9
13
210
235
24
28
38
35
41
241
50
242
^
Data Source Name ."«
10th Report on Carcinogens - NTP
Alternate Crops and Systems (ARS)
Pesticide Properties Database
Contaminant Query
ATSDR Toxicological Profiles
California Department of Pesticide
Regulation (CDPR)
Chemical Carcinogenesis Research
Information System (CCRIS)
Chemical Evaluation Search and
Retrieval (CESARS) - CCOHS
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)
Concise International Chemical
Assessment Documents (CICADs)
CrossFire BEILSTEIN
Derek
Dictionary of Substances and Their
Effects - Knovel
EC Water Directive
Y
N
N
N
Y
N
N
N
N
N
N
N
N
»
'-E
0)
a.
£
a.
U
N
Y
N
Y
N
N
Y
N
N
Y
N
N
N
.5
£
i
N
N
N
N
N
N
N
N
N
N
N
N
Y
c^-
IE
a.
ai
5
CO
N
N
N
N
N
N
N
N
N
N
N
N
N
0
a
'E
0
U
"5
o
z
228
334
5198
269
887
>8000
850
1700
55
8 million+
NA
4600
Unknown
E
c
1
8s
"5
8.
Chemicals,
Inorganics
Pesticides
Chemicals
Pesticides
Carcinogens
Chemicals
CERCLA
Contaminants
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals,
Microbes
Type of Data Elements
Name, CASRN, IARC cancer class, vapor pressure, vapor density, MP, BP, flash point, use,
production, critical effect, exposure potential, releases, occupational exposure limits (PEL)
CASRN, formula, MW, Physical state, BP, MP, Decomposition point, Heat of vaporization, Rate
Con slants- Hydrolysis, Photolysis, VP, Water solubility, Organic solubility, HLC, Kow, Acid
dissociation, Soil sorption, Field dissipation, Soil halflife (aerobic,
Maximum concentration, number of states
Name, CASRN, synonyms, trade names, structure, ID numbers, MW, color, physical state, MP,
BP, density, odor, solubility, log Kow, log Koc, VP, HLC, pKa, hydrolysis rate constant, autoignition
temp, flashpoint, flammability limits, explosive limits, critic
Name, number of products used in
Major Use, Administrative Information, Mutagenicity Study, Card nogeni city Study,
Tumor Promotion, Tumor Inhibition
Properties- Physical and Chemical: Molecular formula, molecular weight, physical state, melting
point, boiling point, flash point, autoignition point, explosive limits, density, specific gravity, Henry's
law constant, pKa, TOD, BOD, COD, conversion facto
Facility Information, Site Name, Address, County, Site SMSA, Federal Facility, NPL Status,
Corporate, Mapping Info, Record of Decision (ROD) Info, EPA Regional, Latitude, Longitude,
Ownership, Site, Incident, Action, Responsibility, Planned Outcome, Urgen
Name, Formula, synonyms, CASRN, ID numbers, MW, density, BP, MP, water solubility, other
solubility, partition coefficients, Log Koc, Log Kow, VP, HLC, production, environmental fate,
BMC/D, ENEV, IARC cancer class, TC(A), CTV, ECx, ICx, LCx, LDx, LO(A)EL
Chemical Name, Effect, Species or Test-System, Route of Application, Kind of Dosing, Method,
Further Details, Results, Half-Life Time; Laboratory Use and Handling; Ecological Data;
Concentration in the Environment; Transport and Distribution; Bioconcentra
Name, Description, References, Endpoint, Comments, LHASA Predictions: Genotoxicity,
Mutagenicity, Skin sensitisation
Toxicity, Physical Properties, Regulatory Requirements, References
Parameter, Parametric value, Unit, Notes, Trueness % of parametric value, Precision % of
parametric value, Limit of detection % of parametric value, Conditions
5" =
Ju.
Biennially
As Needed
Regularly
As Needed
Daily
As Needed
Finished
Monthly
Semi-
annual ly
As Needed
NA
As Needed
Unknown
1 1
= 1
to ~
"S
2001
2001
2004
2003
2004
2003
2002
2002
2002
2002
NA
2004
1998
Page 60 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
ID
59
64
76
78
84
88
89
91
94
92
98
109
111
113
Data Source Name
Endocrine Disrupter Priority Setting
Database (EDPSD)
Environmental Monitoring and
Assessment Program (EMAP)
Genetic Activity Profiles (GAP)
Database
GENE-TOX
Guidelines for Canadian Drinking
Water Quality (CADW): Supporting
Documentation
Health Advisory Documents
Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS
Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA
High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans
Human Exposure Database System
(HEDS)
Information Collection Rule (ICR)
Federal Database
International Register of Potentially
Toxic Chemicals (IRPTC PC) - Data
Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues f JMPR) - Monographs of
Toxicological Endpoints
Proprietor
EPA Office of Prevention,
Pesticides, and Toxic
Substances; EPA, Office of
Science Coordination and Policy
EPA
EPA/IARC
National Library of Medicine;
Created by EPA; maintained by
NIH'sNLM
Health Canada
EPA Office of Water
World Health Organization,
Environment Programme,
Canadian Centre for
Occupational Health and Safety
EPA NCEA
EPA
EPA Office of Research and
Development
EPA Office of Ground Water and
Drinking Water
United Nations Environment
Programme; UNEP, Division of
Technology, Industry, and
Economics
World Health Organization, Food
and Agriculture Organization
World Health Organization, Food
and Agriculture Organization
Assessment Factor Evaluation
Relevance
1> ^;
c t
1 0
Q 0
Y
N
N
N
N
N
N
N
N
Y
Y
N
N
N
_ 0)
® t
Q- 8
O
Y
Y
N
N
N
N
N
N
Y
N
N
Y
N
N
| H
^ u]
E =
°£
Y
N
N
Y
Y
Y
Y
Y
Y
N
N
Y
Y
Y
£
c LU
£ ^
0)
X
Y
N
Y
N
N
N
N
N
N
N
N
N
N
N
This source is considered relevant for the CCL
Universe because it contains data elements
derived from toxicological studies and unique
elements derived for measurements of
contaminants in water, providing an indicator of
occurrence.
This source is considered relevant because it
contains geographical and water quality data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains information on
mutagenicity, which may be an indicator of
potential health effects.
Universe because it contains information on
mutagenicity, which may be an indicator of
potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements
(RfDs) from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains information that is
related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
Redundancy
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
'
'rebuild ant ^
redundant.
'
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
Completeness
'o
c g
o ®
5 '1
3 0)
r
N
Y
Y
Y
Y
Y
Y
Y
N
N
Y
Y
Y
Y
U
S "*=
z E
« o-
8 o:
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
•£
o
u_
"5
Tabular
Tabular
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Tabular
Unknown
Tabular
Monographic
Monographic
c
o
N
N
N
N
N
N
N
N
N
N
N
N
N
N
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source has been withdrawn; it is no longer
available online.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
Page 61 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
ID
64
76
78
84
88
89
91
94
92
98
109
111
113
^
Data Source Name ."«
Endocrine Disrupter Priority Setting
Database (EDPSD)
Environmental Monitoring and
Assessment Program (EMAP)
Genetic Activity Profiles (GAP)
Database
GENE-TOX
Guidelines for Canadian Drinking
Water Quality (CADW): Supporting
Documentation
Health Advisory Documents
Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS
Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA
High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans
Human Exposure Database System
(HEDS)
Information Collection Rule (ICR)
Federal Database
International Register of Potentially
Toxic Chemicals (IRPTC PC) - Data
Profiles -UNEP Chemicals
Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - Monographs of
Toxicological Endpoints
N
N
N
N
N
N
N
N
N
N
N
N
N
N
»
'-E
a.
£
a.
U
Y
N
N
N
N
N
N
N
Y
N
N
Y
N
N
.5
£
i
N
N
N
N
Y
Y
N
N
N
N
Y
N
N
N
^
.c
a.
ai
5
CO
N
N
N
N
N
N
N
N
N
N
N
N
N
N
0
5
E
0
U
"5
o
z
87000
170
>750
>3000
197
181
109
200
>180
46
10
8000
1050
1000
c
_c
1 =
Ss
"5
8.
Potential
Endocrine
Chemicals
Chemicals
Chemicals
.
Chemicals,
Microbes,
Inorganics
Chemicals
Chemicals
High Production
Metals, VOCs,
Pathogens, DBPs
Chemicals
Chemicals
Pesticides
Type of Data Elements
Name, CASRN, HE and Occurrence data
Assemblage Counts, Chlorophyll Data, Assemblage Metrics, Counts Data, Diatom Data,
Identification Codes Data, Invertebrate Metrics, Metals, Site Information, Streams
Chemistry, Watershed Characteristics, Benthic Data, Fish Data, Fish Tissue Contaminants, G
Chemical name, CAS registry number, test code, test endpoint, test results, highest ineffective
dose (HID) or lowest effective dose (LED), reference number, reference citation
Name, CASRN, Mutagenicity Studies, Assay Type, Evaluation Results, Panel Report, Reference,
Species/Cell Type, Species/Cell Type Sex, Taxonomic Name & Assay
Name, synonyms, formula, iMAC, MAC, IARC cancer class, ADI, MTD, LDx, NO(A)EL, lifetime risk
Dose response assessments, Exposure from drinking water, Exposure from environmental media
other than water, Hazard identification, Physical and chemical properties, Regulatory
determination and characterization of risk, Toxicokinetics, Uses and environme
CASRN, Physical/Chemical, Environmental Fate, Production/Use, Occurrence, Ecological Toxicity,
Species, Route, Dose, Frequency, Duration, Critical Effect, CLV, ERL, MAC, MR(es)L, MXL,
RECL, STEL, TWA, LCx, LDx, LO(A)EL
Name, CASRN, Slope factor, Unit risk, RfD, RfC
Name, CASRN, Structure, Acute Toxicity (LD50), Repeated Dose Toxicity (NOAEL, LOAEL),
Genetic Toxicity in vitro, Genetic Toxicity in vivo, Reproductive Toxicity, Developmental Toxicity,
Acute Ecotoxicity (fish and aquatic invertebrates), Photodegradation,
Contaminant Class, Sampling Method, Sampling Device, Sample Type Code, Concentration,
Qualifier, Method Det. Limit, Data Quality Flag, State, County, Samp. Location, Household ID,
Respondent #, Sample ID, Samp. Start Date, Samp. End Date
DBP Occurrence Concentrations
Environmental fate, Production, Mammalian Toxicity
Summary of evaluations, Recommended dietary allowance, Carcinogenicity, Mutagenicity,
Reproduction, Teratogenicity, Acute Toxicity, Short term studies, Long-term studies, Observations
in humans, Immune response, Ototoxicity, Microbiological effects
Name, CASRN, Formula, Structure, ADI, RfD, DWGLs, pTDI, RfD, LDx, NO(A)EL, LO(A)EL
5" =
Ju.
None
Unknown
None
As Needed
No
Mandated
Schedule
As Needed
Unknown
As Needed
As Needed
Finished
As Needed
Unknown
As Needed
~° "o
1 1
= 1
"w ~
"S
2002
2002
1999
2003
2002
2002
2002
2002
2003
2002
1998
2002
1974
2003
Page 62 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
ID
114
139
140
143
146
148
149
150
156
152
163
161
160
Data Source Name
Laboratory Chemical Safety
Summaries (LOSS) - Howard
Hughes Medical Institute and
National Academy of Science
National Health and Nutrition
Examination Survey (NHANES)
National Human Adipose Tissue
Survey (NHATS)
National Institute for Occupational
Safety and Health (NIOSH) - Index
of Occupational Health Guidelines
for Chemical Hazards
National Occupational Exposure
Survey (NOES)
National Sanitary Foundation (NSF) -
Additives Standards 60 and 61
National Sediment Inventory (NSI)
National Toxicology Program (NTP)
Health and Safety Profiles
Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact
Organisation for Economic Co-
operation and Development (OECD)
Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support Wording
Group
Permit Compliance System (PCS)
Database
Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)
Proprietor
Howard Hughes Medical Institute,
National Academy of Science
CDC National Center for Health
Statistics
EPA Office of Toxic Substances
CDC National Institute for
Occupational Safety and Health
(NIOSH)
CDC National Institute for
Occupational Safety and Health
(NIOSH)
National Sanitary Foundation
EPA Office of Water, OST
National Toxicology Program;
NIH
EPA Office of Pollution
Prevention and Toxics
Organisation for Economic Co-
operation and Development
Technical Support Working
Group
EPA OECA
EPA (OPPT), Environmental
Science Center, Syracuse
Research Corporation
Assessment Factor Evaluation
Relevance
1> ^;
c t
1 0
Q 0
N
N
N
N
N
N
N
N
N
N
N
N
N
_ 0)
® t
Q- S
O
N
Y
Y
N
Y
N
Y
N
Y
Y
N
Y
Y
| H
^ u]
E =
°£
Y
N
N
Y
N
Y
N
Y
Y
Y
Y
N
N
S
c LU
£ ^
0)
X
N
N
N
N
N
N
N
N
N
N
N
N
N
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in either the blood or urine,
providing an indicator of occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in human adipose tissue, providing
an indicator of occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information that is
related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains information on
health effects standards for drinking water.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in sediments (which can contribute
contaminants to drinking water), and can indicate
potential occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it is a list of HPV chemicals,
which may indicate possible occurrence. It also
contains data elements from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
discharge of waste to rivers, which may indicate
potential occurrence.
This source is considered relevant for the CCL
Universe because it could be a source of
information on persistence, providing an indicator
of occurrence.
Redundancy
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
Completeness
'o
c g
o ®
5 '1
3 0)
r
Y
Y
Y
Y
Y
Y
N
Y
N
Y
N
Y
N
U
S "*=
z E
« o-
8 o:
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
•£
o
Li-
IS
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Monographic
Tabular
Tabular &
Monographic
Tabular/Model
c
o
N
N
N
N
N
Y
N
N
N
N
Y
N
N
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
This source does not meet retrievability criteria
because the data are not formatted for automated
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, however some tabular data have been
obtained from ERG.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
This source does not meet retrievability criteria
because the data are not formatted for automated
This source does not meet retrievability criteria
because it is only available through a subscription.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates.
Page 63 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
ID
114
139
140
143
146
148
149
150
156
152
163
161
160
^
Data Source Name ."«
Laboratory Chemical Safety
Summaries (LCSS) - Howard
Hughes Medical Institute and
National Academy of Science
National Health and Nutrition
Examination Survey (NHANES)
National Human Adipose Tissue
Survey (NHATS)
National Institute for Occupational
Safety and Health (NIOSH) - Index
of Occupational Health Guidelines
for Chemical Hazards
National Occupational Exposure
Survey (NOES)
National Sanitary Foundation (NSF)-
Additives Standards 60 and 61
National Sediment Inventory (NSI)
National Toxicology Program (NTP)
Health and Safety Profiles
Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact
Sheets
Organisation for Economic Co-
operation and Development (OECD)
Integrated HPV Database
Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support Wording
Group
Permit Compliance System (PCS)
Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)
N
N
N
N
N
N
N
N
N
N
N
N
N
»
'-E
a.
£
a.
U
N
N
N
Y
N
N
N
N
N
Y
N
N
Y
.5
o
i
N
N
N
N
N
N
N
N
N
N
N
N
N
7;
.c
a.
ai
5
CO
N
N
N
N
N
N
N
N
N
N
N
N
N
0
5
E
0
U
"5
o
z
88
27
150
675
Unknown
NA
220
NA
31
5,235
10000
NA
100000
c
_c
1 =
Ss
"5
8.
Laboratory
chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Toxic chemicals
Chemicals
Chemicals
(persistent,
bioaccumulative,
toxic)
Type of Data Elements
Substance, Formula, Physical Properties, Odor, Vapor Density, Vapor Pressure, Flash Point,
Autoignition Temperature, Toxicity Data, Major Hazards, Toxicity, Flammability and Explosibility,
Reactivity and Incompatibility, Storage and Handling, Accidents, D
CAS RN, Parameter, Detection limit, Number of samples, Mean, Median, 5th percentile, 95th
percentile, Percent above detection limit
Chemical name, CAS RN, Year, Number of Analyses, Arithmetic/Geometric Mean, Lowest
Arithmetic/Geometric Mean, Number of Analyses with Lowest Arithmetic/Geometric Mean, Highest
Arithmetic/Geometric Mean, Number of Analyses with Highest Arithmetic/Geometric
Formula, Structure, Appearance and odor,
Physical Data, Reactivity, Flammability, OSHA PEL, NIOSH REL, ACGIH TLV, Rationale for limits,
Routes of exposure, Summary of toxicology, Signs and symptoms of exposure, Emergency
procedures, Exposure Sources and
CAS RN, Name, Standard industrial classification (SIC) code, Number of workers exposed to the
substance, Number of facilities handling the material
Unknown
Analyte sampled, Mean, Max, Median, Min, Measured/estimated value, Fraction organic carbon,
Nondetectflag, Number of samples, Units
BP, Carcinogen! city, Critical effects, Dose, Duration, GenTox, GMM Abstract, GMM Care, GMM
GenTox, GMM Neo, GMM Nonneo, Hazard class, MP, Mutation Data, Other toxicity data, Path,
RACE Abstract, Rationale for testing, RDGT Abstract, Reactivity, Route, SAX
What is the contaminant, how is it used, and how might 1 be exposed? What happens to the
contaminant in the environment? How does the contaminant affect human health and the
environment? What EPA program offices regulate the contaminant, and under what la
Name, CASRN, SIDS status
"Published toxicity levels"
Facility, Address, Activity Status, Permit Type, Issued Date, Expired Date, USGS Hydro Basin,
Stream Segment, Flow, Receiving Stream Class, Federal_grant_ind, Receiving Waters, Final
Limits Ind Pretreatment Code, Sludge Information, Permit Documents, Insp
Predicted persistence (half life) in air, water, soil, and sediment, Bioaccumulation (BCF), Fish ChV,
Includes structural information
5" =
Ju.
Unknown
Unknown
Finished
As needed
Finished
Every five
years
As Needed
Unknown
Finished
ry
As Needed
Monthly
As Needed
~° "o
•£ 1
= 1
"w ~
"S
Unknown
2002
1990
1995
1983
2002
1993
2003
1994
2000
Unknown
2004
2003
Page 64 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
ID
159
262
168
269
170
180
176
1/9
232
182
189
190
Data Source Name
Pesticide Action Network (PAN)
Pesticide Database
Pesticide Handler Exposure
Pesticide Product Information
Pesticide Tolerance Index System
Priority Substances Assessment
Program - Health Canada
Priority-based Assessment of Food
Additives (PAFA) Database
Registry of Toxic Effects of
Chemical Substances (RTECS)
Reregistration Eligibility Decision
Documents (REDDs) - EPA OPP
Rijksinstituut voor Volksgesondheid
en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report
Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for Economic
Co-operation and Development
(OECD)
Source Ranking Database (3RD)
State Drinking Water Data Sets
Proprietor
Pesticide Action Network
EPA
EPA
EPA
Health Canada
FDA Center for Food Safety and
Applied Nutrition
CDC National Institute for
Occupational Safety and Health
(NIOSH)
EPA Office of Pesticide
Programs
Rijksinstituut voor
Volksgesondheid en Milieu
(RIVM), The Netherlands
EPA
International Programme for
Chemical Safety, United Nations
Environmental Program;
UNEP/IRPTC in Geneva,
Switzerland
EPAOPPT
EPA OGWDW; The Cadmus
Group, Inc.
Assessment Factor Evaluation
Relevance
^
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
ID
159
262
168
170
157
180
176
179
232
182
189
190
^
Data Source Name ."«
Pesticide Action Network (PAN)
Pesticide Handler Exposure
Database
Pesticide Product Information
System (PPIS)
Pesticide Tolerance Index System
(TISInfo)
Priority Substances Assessment
Program - Health Canada
Priority-based Assessment of Food
Additives (PAFA) Database
Registry of Toxic Effects of
Chemical Substances (RTECS)
Reregistration Eligibility Decision
Documents (REDDs) - EPA OPP
Rijksinstituut voor Volksgesondheid
en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report
Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for Economic
Co-operation and Development
(OECD)
Source Ranking Database (3RD)
State Drinking Water Data Sets
N
N
Y
N
N
N
N
N
N
N
N
N
N
»
'-E
a.
£
a.
U
N
N
N
N
N
N
N
N
N
N
N
N
N
.5
£
i
N
N
N
N
N
N
N
N
N
N
N
N
N
^
.c
a.
ai
5
CO
N
N
N
N
N
N
N
N
N
N
N
N
N
0
5
E
0
U
"5
o
z
6400
Unknown
90000
Unknown
69
3000
156485
176
50
Unknown
92
1377
>60
c
_c
1 =
Ss
"5
8.
Pesticides
Pesticides
Pesticides
Pesticides
Chemicals
Food Additives
Chemicals
Pesticides
Soil Contaminants
(Metals,
Aromatics,
Chlorinated HCs,
la.)
Chemicals
High Production
Volume
Chemicals
Mostly Regulated
Chemicals
Type of Data Elements
Chemical Name, CAS Number, U.S. EPA PC Code, CA DPR Chem Code, Molecular Weight, Use
Type, Chem Class, Route of Exposure, Symptoms, First Aid, PAN Bad Actor Chemical, Acute
Toxicity, Carcinogen, Cholinesterase Inhibitor, Ground Water Contaminant, Developm
Pesticide exposure data
Name, CASRN, Registrant name and address, Chemical ingredients, Toxicity category, Product
names, Distributor brand names, Site/pest uses, Pesticidal type, Formulation code, and
Registration status
Unknown
Name, Synonyms, CASRN, Formula, BMC, BMD, ENEV, MTD, CTV, ECx, ICx, LDx, LO(A)EL,
NO(A)EL, SMR, TumCx, TumDx
Genetic Toxicity and Cytotoxicology, Acute Toxicology, Oral Toxicology, HNEL, Toxicological
effect, Exposure, ADI, LD High, LEL
LDx, NOAEL, LOAEL, Reproductive/ Developmental, Mutation, Irritation, Tumorigenic data
Name, Synonyms, DWLOC, PAD, RfD, MCL, SF, LCx, LDx, LO(A)EL, MOE, NO(A)EL, HOT
Absorption Factors, ADI, Backgrnd Exposure, CR, Crinhal reliability, Crinhal value, Croral
reliability, Croral value, Dose Ranges, HUM-TOX SCC, IARC Cancer Group, LO(A)EL, MAC, MPR:
oral, inhalation, MRL, MTD, NO(A)EL, Old MPR?, pCRinhal reliability, pCRi
Water System Name, Principal County Served, Population Served, Primary Water Source Type,
System Status, Water System ID, Concentration, Violations
Name, Formula, Synonyms, CASRN, Other IDs, ADI, ECx, LCx, LDx, NO(A)EL
Unknown
Drinking water occurrence concentrations
5" =
Ju.
As Needed
Unknown
Weekly
None
As Needed
As Needed
Quarterly
As Needed
None, it is a
stand-alone
report.
Unknown
As Needed
None
Finished
~° "o
•£ 1
= 1
"w ~
"S
2002
Unknown
2004
2003
2002
2003
2003
2003
2001
Unknown
2004
2003
1997
Page 66 of 229
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
ID
192
194
202
181
240
208
9^0
213
220
229
8b
40
Data Source Name
State of New Jersey Hazardous
Substances Right to Know Fact
Sheets
STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STORET - STORage and RETrieval
Superfund Contract Laboratory
Program (SCLP) Water/Soil Data
The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)
TOMES PLUS, MICROMEDEX -
Thomson-Micromedex
Total Exposure Assessment
Methodology Study (TEAM)
TSCATS - Toxic Substances Control
US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets
WHO Guidelines for Drinking Water
Quality: Chemical Aspects: Index of
Chemicals
WHO Recommended Classification
of Pesticides by Hazard (CPH)
Proprietor
State of New Jersey
Chemical Abstracts Service
EPA
EPA Headquarters Analytical
Operations/Data Quality Center
(AOC) in the Office of Emergency
and Remedial Response (OERR)
Accel rys
Thomson Micromedex
EPA
Syracuse Research Corporation;
Developed and maintained by
SRC for EPA
U.S. Army Center for Health
Promotion and Medicine
UKWater Industry Research &
Wrc-NSF Ltd.
World Health Organization
International Programme for
Chemical Safety, World Health
Organization, International
Labour Organisation, United
Nations Environment Programme
Assessment Factor Evaluation
Relevance
^
-------
EPA-OGWDW
CCL 3 Chemicals: Identifying the Universe
Appendix 3. CCL 3 Universe Supplemental Data Sources
EPA815-R-08-002
February 2008 - Draft
Source Identifi
ID
192
194
202
181
240
208
250
213
220
229
85
40
^
Data Source Name ."«
State of New Jersey Hazardous
Substances Right to Know Fact
Sheets
STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STORET - STORage and RETrieval
Superfund Contract Laboratory
Program (SCLP) Water/Soil Data
The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)
TOMES PLUS, MICROMEDEX-
Thomson-Micromedex
Total Exposure Assessment
Methodology Study (TEAM)
TSCATS - Toxic Substances Control
Act Test Submissions
US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets
WHO Guidelines for Drinking Water
Quality: Chemical Aspects: Index of
Chemicals
WHO Recommended Classification
of Pesticides by Hazard (CPH)
N
Y
N
N
N
N
N
N
N
N
N
N
»
'-E
a.
£
a.
U
N
N
N
Y
N
N
N
N
N
N
N
N
.5
£
i
N
N
Y
N
N
N
N
N
N
N
N
N
7;
.c
a.
ai
5
CO
N
N
N
N
N
N
N
N
N
N
N
N
0
5
E
0
U
"5
o
z
1000
NA
NA
150
NA
4000
30
8000
24
450
143
500
c
_c
1 =
Ss
"5
8.
Chemicals
Chemicals
Chemicals,
Biologicals,
Physical Agents
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Weaponry Agents
Chemicals
Chemicals
Pesticides
Type of Data Elements
Field, Common Name, CAS RN, DOT Number, RTK Substance Number, Date, Revision, Hazard
Summary, Workplace Exposure Limits, Acute Health Effects, Chronic Health Effects, Cancer
Hazard, Reproductive Hazard, Other Long-term Effects
Substance identity information, inventory status, source of information, and summaries of
regulatory activity, reports, and other compliance information
Estimated, Nitrogen, ammonia (NH3) as NH3 (mg/l), Estimated, Fecal Coliform (#/100ml),
Estimated Total Coliform (#/100ml)
Mean, Min, Max, Median, Measured/Estimated Concentrations
SMILES, Compund Name, Primary ID, Secondary ID, Rodent Carcinogenicity, Ames Mutagenicity,
Rat Oral LD50, Rat Chronic LOAEL, Developmental Toxicity Potential, Skin Sensitization, Fathead
Minnow LC50, Daphnia Magna EC50, Weight of Evidence Rodent Carcinoge
Identification & Synonyms, Range of Toxicity, Toxicity/Biomedical Effects, Environmental
Fate/Exposure Potential, Chronic Health Hazard Assessments for Non-Carcinogenic Effects,
Carcinogenicity Assessments for Lifetime Exposure
Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season
CAS RN, Name, Study Purpose, Organism, Rte Admin, Test, Ref
Chemical Formula, Description, Overexposure Effects, Reactivity Data, Toxicity Values, Exposure
Unknown
Name, synonym, formula, MP, BP, density, VP, water solubility, Log Kow, odor thresh olds, use,
environmental fate, ADI, CR, GV, IARC cancer class, TDI, NO(A)EL, LO(A)EL, LDx, HRL,
reproductive, embryotoxicity, teratogenicity, mutagenicity
Dose, Critical Effect, BMC, BMD, ENEV, Cancer Group, TC(A), CTV, ECx, ICx, LCx, LDx,
LO(A)EL, NO(A)EL
3 =
Ju.
As Needed
Weekly
As Needed
As Needed
NA
Unknown
None
As Needed
As Needed
2/year
As Needed
Semi-
annual ly
~° "o
1 1
= I
to ~
"S
2003
2003
2002
NA
2002
1999
2002
1998
2003
1996
2002
Page 68 of 229
-------
EPA-OGWDW
CCL 3 Chemicals:
Identifying the Universe
EPA815-R-08-002
February 2008 - DRAFT
Appendix 4. CCL 3 Data Source Descriptions
Data Source Name
Identification Number
Data Source Description
10th Report on Carcinogens - NTP
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
1
The Report on Carcinogens (RoC) is an informational scientific and public health
document that identifies and discusses substances (including agents, mixtures, or exposure
circumstances) that may pose a carcinogenic hazard to human health. It serves as a
meaningful and useful compilation of data on (1) the carcinogenicity (whether it causes
cancer), genotoxicity (whether it causes damage to genes), and biologic mechanisms (how it
works in the body) of the listed substances in people and/or in animals, (2) the potential for
human exposure to these substances, and (3) Federal regulations to limit exposures. The
RoC does not present quantitative assessments of the carcinogenic risk of these
substances. Listing of substances in the RoC, therefore, does not establish that these
substances present carcinogenic risks to individuals in their daily lives. Such formal risk
assessments are the responsibility of the appropriate federal, state, and local health
regulatory and research agencies. The substances listed in the RoC are either known or are
reasonably anticipated to cause cancer in humans under certain exposure circumstances.
(description from website)
Department of Health and Human Services - National Toxicology Program
Thomas J. Goehl, PhD
EHP
NIEHS/NIH MD EC-15
PO Box 12233
Research Triangle Park, NC 27709-2233
Phone:919-541-7961
Fax:919-541-0273
E-mail: goehl@niehs.nih.gov
Name, CASRN, IARC cancer class, vapor pressure, vapor density, MP, BP, flash point,
use, production, critical effect, exposure potential, releases, occupational exposure limits
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ehp.niehs.nih.aov/roc/toc10.html
Data Source Name
Identification Number
Data Source Description
Proprietor
8(e) TRIAGE Chemical Studies Database - OPPT
Searchable database of scientific studies on the health and environmental effects of toxic
chemicals related to Section 8(e) of TSCA.
In order to help reduce the risks of chemicals in the environment, EPA recognizes the
importance of providing the public with access to the information collected under TSCA and
other environmental statutes. One important information gathering tool under TSCA is found
in Section 8(e). Under Section 8(e), manufacturers, importers, and distributors of chemical
substances and mixtures are required to inform EPA of studies that reasonably support the
conclusion that the chemicals present a "substantial risk of injury" to human health or the
environment. In 1991 OPPT initiated the Compliance Audit Program (CAP). The CAP was a
voluntary program that encouraged companies to audit their files for information that was
required by 8(e). It provided reduced monetary penalties for companies submitting studies
that were past the statutory submittal deadline. EPA received about 10,000 submissions
under the CAP, in addition to the approximately 400 non-CAP 8(e)s the Agency receives
each year. The Database includes the majority of the CAP and non-CAP submissions
received after 1991. (description from website)
EPA Office of Prevention, Pesticides, and Toxic Substances
Page 69 of 229
-------
EPA-OGWDW
CCL 3 Chemicals:
Identifying the Universe
EPA815-R-08-002
February 2008 - DRAFT
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
1200 Pennsylvania Avenue, N. W.
Washington, DC 20460
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/docs/8e triad/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Aerometric Information Retrieval System/Air Quality Subsystem
(AIRS/AQS)
AIRS AQS is a searchable database of hourly and annual average air emissions and
monitoring data from national (i.e., all 50 States, Puerto Rico, and the U.S. Virgin Islands)
and international monitoring stations. AIRS AQS provides reporting information from three
databases (Aerometric Information Retrieval System (AIRS), National Emissions Trends
(NET), and National Toxics Inventory (NTI)) for the six criteria pollutants (i.e., carbon
dioxide, lead, nitrogen dioxide, ozone, particulate matter 10 and 2.5, and sulfur dioxide) and
188 hazardous air pollutants. The three databases provide ambient concentrations of criteria
air pollutants at monitoring sites; annual emissions of criteria air pollutants from point, area,
and mobile sources; and estimates of annual emissions of hazardous air pollutants from
point, area, and mobile sources, (description from website)
EPA Office of Air and Radiation
If you need assistance accessing any of the material in AQS, User Support is provided
through the EPA Call Center. The toll free number is 866-411-4EPA (866-411-4372). Please
contact them first with any questions about using the AQS application.
name, air quality standard, number observations, max values (1 hour), number exceedences
(1 hour), max values (3 hour), number exceedences (3 hour), max values (8 hour), number
exceedences (8 hour), max values (24 hour), number exceedences (24 hour), annual mean,
number exceedences (year), quarterly averages, site ID, site address, city, county, state,
EPA Region
This source is considered relevant for the CCL Universe because it contains information on
air emissions, which may indicate potential occurrence.
It meets considerations because it is peer reviewed.
This source is redundant with Idaho Toxic and Hazardous Substances - Idaho Division of
Building Safety (source 100).
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/ttn/airs/airsaas/aasweb/agswebhome.htm
Data Source Name
Identification Number
Data Source Description
AGRICultural OnLine Access (AGRICOLA)
AGRICOLA (AGRICultural OnLine Access) is a bibliographic database of citations to the
agricultural literature created by the National Agricultural Library (NAL) and its cooperators.
Production of these records in electronic form began in 1970, but the database covers
materials in all formats, including printed works from the 15th century. The records describe
publications and resources encompassing all aspects of agriculture and allied disciplines,
including animal and veterinary sciences, entomology, plant sciences, forestry, aquaculture
and fisheries, farming and farming systems, agricultural economics, extension and
education, food and human nutrition, and earth and environmental sciences. Although the
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
AGRICOLA database does not contain the materials, thousands of AGRICOLA records are
linked to full-text documents online, with new links added daily, (description from website)
National Agricultural Library (NAL) and its cooperators, part of the U.S. Department of
Agriculture's (USDA) Agricultural Research Service
AGRICOLAhelp@nal.usda.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers, authors, title, journal, date of publication
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is redundant with Cambridge Scientific Abstracts (source 15), but that source is
a subscription, whereas this source is free of charge.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://aaricola.nal.usda.gov/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
All the Virology on the WWW
5
This web site, run by a medical researcher, provides links to a broad variety of virology-
related resources on the Internet. The site includes a "Big Picture Book of Viruses," which
provides web based visuals, but may also be used as a taxonomy resource.
Virology.net; Dr. David M. Sander (a medical researcher; corporate sponsorship)
David M. Sander, Ph.D.
david.sander@virology.net
links to virology research and data sites, specific virus servers and information, AIDS
information/research, Plant virus servers and information, viral diseases, vaccines, and
treatments, organizations and groups of interest to virologists, educational resources, general
virology information and news, and related internet resources for virologists; virus pictures
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.viroloav.net
Data Source Name
Identification Number
Data Source Description
Alternate Crops and Systems (ARS) Pesticide Properties Database
9
The ARS Pesticide Properties Database (PPD) has been developed to provide water quality
modelers and managers a list of the pesticide properties most important for predicting the
potentials of pesticides to move into ground and surface waters under a range of weather
and soil conditions.
The ARS PPD is a compendium of chemical and physical properties of 334 widely used
pesticides. Information included in the database focuses on 16 of the most important
properties that affect pesticide transport and degradation characteristics. The database is
administered by the Alternate Crops & Systems Laboratory in Beltsville, Maryland, which
has the responsibility for adding pesticides and new data as they become available. A
steering committee that represents database users gives advice on the form and content of
the database, (description from website)
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Alternate Crops & Systems Laboratory, United States Department of Agriculture
Technical Contact: Don Wauchope
ARS, Southeast Watershed Res. Lab.
don@tifton.cpes.peachnet.edu
CASRN, formula, MW, Physical state, BP, MP, Decomposition point, Heat of vaporization,
Rate Constants-Hydrolysis, Photolysis, VP, Water solubility, Organic solubility, HLC, Kow,
Acid dissociation, Soil sorption, Field dissipation, Soil halflife (aerobic, anaerobic)
This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be used as an indicator of potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.arsusda.gov/acsl/services/ppdb/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Analytical ABSTRacts (ANABSTR)
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
ANABSTR contains about 305,000 abstracts covering many sources (i.e., international
journals, books, technical reports, and conference proceedings) of literature on analytical
chemistry. Abstracts date from 1980.
Chemical Abstracts Service; Produced by the Royal Society of Chemistry in England, and
distributed by FIZ CHEMIE of Germany
The Royal Society of Chemistry
Thomas Graham House, Science Park
Milton Road
Cambridge CB4 4WF, UK
Phone: (+44 1)223/432110
Fax: (+441)223/423623
Email: stnhlpuk@rsc.org
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.stn-international.de/stndatabases/databases/anabstr.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Aquatic Pollution and Environmental Quality - Cambridge Scientific
Abstracts
Because of increasing global concern over the consequences of marine and aquatic
pollution, a separate volume addressing this subject was added to the ASFA series. ASFA 3
is the only abstracts journal devoted exclusively to research and policy on the contamination
of oceans, seas, lakes, rivers, and estuaries. ASFA 3 contains information that will prove
essential to specialists who deal in any capacity with aquatic environments and marine
pollution problems, including biologists, oceanographers, limnologists, environmental
engineers and scientists, industrial engineers, waste managers, corporate regulatory affairs
managers, and government officials, (description from website)
Cambridge Scientific Abstracts
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.csa.com/csa/factsheets/asfa-3.shtml
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
AQUatic toxicity Information Retrieval (AQUIRE)
8
AQUIRE is one of three EPA databases that make up the EPA ECOTOXicology (ECOTOX)
database system. AQUIRE, which contains data from national and international scientific
papers on toxicity to aquatic organisms and plants, has over 214,000 aquatic literature
references that cover research from 1970 to the present.
The aquatic data were originally presented in a separate EPA database called AQUIRE
(AQUatic Information Retrieval). AQUIRE was established in 1981 by the EPA and was
maintained by the Mid-Continent Ecology Division of the National Health and Environmental
Research Laboratory. In 1995, the AQUIRE database became a component of the ECOTOX
database. The aquatic data include freshwater, marine and estuarine exposures to animal and
plant species. Chemical exposure must be through water, diet, injection or skin; sediment
studies are not included unless a pore (or overlying) water concentration is provided. The
database includes studies dating back to 1915, but the majority of the data encompass test
results reported from 1970 to the present. The aquatic data were used historically for
deriving structure-activity relationship to estimate the toxicity of chemicals lacking toxicity
data and for the derivation of water quality criteria values. To this end, the database has
focused on encoding standard calculated test endpoints, such as the LC50, that can be used
to compare toxic effects across species, chemicals, and endpoints. The aquatic component
does not include dose response information. If a calculated endpoint or statistically
analyzed data were not presented, then the data are ranged into a single effect record.
(description from website)
EPA, Office of Research and Development (ORD), and National Health and Environmental
Effects Research Laboratory (NHEERL), Mid-Continent Ecology Division
ECOTOX Support at T: (218)529-5225 or E-mail: ecotox.support@epa.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is redundant with ECOTOX (source 57).
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.epa.gov/med/Prods Pubs/ecotox.htm
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Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
ASFA 3: Aquatic Pollution and Environmental Quality - Cambridge
Scientific Abstracts
10
Because of increasing global concern over the consequences of marine and aquatic
pollution, a separate volume addressing this subject was added to the ASFA series. ASFA 3
is the only abstracts journal devoted exclusively to research and policy on the contamination
of oceans, seas, lakes, rivers, and estuaries. ASFA 3 contains information that will prove
essential to specialists who deal in any capacity with aquatic environments and marine
pollution problems, including biologists, oceanographers, limnologists, environmental
engineers and scientists, industrial engineers, waste managers, corporate regulatory affairs
managers, and government officials, (description from website)
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is identical to Aquatic Pollution and Environmental Quality - Cambridge Scientific
Abstracts (source 7).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.csa.com/csa/factsheets/asfa-3.shtml
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Assessment Tools for the Evaluation of Risk (ASTER)
11
ASTER integrates the AQUIRE toxic effects database and a Quantitative Structure Activity
Relationships (QSAR) structure-activity based data system. The database is designed to
provide empirical toxicology data for discrete chemicals where available. Where discrete
data are not available, the database draws on QSAR-based, mechanistically modeled
predictive estimates for ecotoxicity endpoints, chemical properties, biodegradation, and
environmental partitioning. The QSAR database contains measured physicochemical
properties for chemicals, including 56,000 molecular structures stored in the Simplified
Molecular Input Line Entry System (SMILES) format.
(description from website)
EPA ORD, NHEERL, Mid-Continent Ecology Division (Duluth, MN)
Scientific Outreach Program
U.S. Environmental Protection Agency
Office of Research and Development
National Health and Environmental Effects Research Laboratory
Mid-Continent Ecology Division (MED)
6201 Congdon Boulevard
Duluth, Minnesota 55804
Telephone: 218-529-5225
Fax: 218-529-5003
E-mail: ecotox.support@epa.gov
Name, CASRN, SMILES, formula, molecular weight, MP, BP, VP, heat of vaporization, water
solubility, log P, pKa, log Koc, HLC, hydrolysis half life, BOD half life, MacKay level
This source does not meet relevance criteria because it only contains information on
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Redundancy Explanation
Retrievability Explanation
Source URL
ecological toxicity.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.qov/med/prods pubs.htm - databases
Data Source Name
Identification Number
Data Source Description
ATSDR CERCLA Priority List
12
The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA)
section 104 (i), as amended by the Superfund Amendments and Reauthorization Act (SARA),
requires ATSDR and the EPA to prepare a list, in order of priority, of substances that are
most commonly found at facilities on the National Priorities List (NPL) and which are
determined to pose the most significant potential threat to human health due to their known
or suspected toxicity and potential for human exposure at these NPL sites. CERCLA also
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
requires this list to be revised periodically to reflect additional information on hazardous
substances.
This CERCLA priority list is revised and published on a 2-year basis, with a yearly informal
review and revision. Each substance on the CERCLA Priority List of Hazardous Substances
is a candidate to become the subject of a toxicological profile prepared by ATSDR and
subsequently a candidate for the identification of priority data needs. This priority list is
based on an algorithm that utilizes the following three components: frequency of occurrence
at NPL sites, toxicity, and potential for human exposure to the substances found at NPL
sites. This algorithm utilizes data from ATSDR's HazDat database, which contains
information from ATSDR's public health assessments and health consultations.
It should be noted that this priority list is not a list of "most toxic" substances, but rather a
prioritization of substances based on a combination of their frequency, toxicity, and potential
for human exposure at NPL sites.
Thus, it is possible for substances with low toxicity but high NPL frequency of occurrence
and exposure to be on this priority list. The objective of this priority list is to rank substances
across all NPL hazardous waste sites to provide guidance in selecting which substances will
be the subject of toxicological profiles prepared by ATSDR. (description from website)
Agency for Toxic Substances and Disease Registry
Agency for Toxic Substances and Disease Registry
Division of Toxicology
1600 Clifton Road NE, Mailstop E-29
Atlanta, GA 30333
Phone:1-888-422-8737
Fax:1-404-498-0057
E-mail: ATSDRIC@cdc.gov
Name, CASRN, rank
This source is considered relevant for the CCL Universe because the basis for developing
this list is ATSDR's prioritization of chemicals found at NPL sites and that ATSDR believes
may pose a human health risk.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.atsdr.cdc.gov/clist.html
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Identification Number
Data Source Description
Proprietor
ATSDR Internet HazDat - Site Contaminant Query
13
According to the HazDat website, HazDat "is the scientific and administrative database
developed to provide access to information on the release of hazardous substances from
Superfund sites or from emergency events and on the effects of hazardous substances on
the health of human populations. The following information is included in HazDat: site
characteristics, activities and site events, contaminants found, contaminant media and
maximum concentration levels, impact on population, community health concerns, ATSDR
public health threat categorization, ATSDR recommendations, environmental fate of
hazardous substances, exposure routes, and physical hazards at the site/event. In addition,
HazDat contains substance-specific information such as the ATSDR Priority List of
Hazardous Substances, health effects by route and duration of exposure, metabolites,
interactions of substances, susceptible populations, and biomarkers of exposure and
effects. HazDat also contains data from the U.S. Environmental Protection Agency (EPA)
Comprehensive Environmental Response, Compensation, and Liability Information System
(CERCLIS) database, including site CERCLIS number, site description, latitude/longitude,
operable units, and additional site information, (description from website)
Agency for Toxic Substances and Disease Registry
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Dr. Sandra Susten, E-mail: sss2@cdc.gov
Maximum concentration, number of states
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.atsdr.cdc.gov/hazdat.html
Data Source Name
Identification Number
Data Source Description
ATSDR Minimal Risk Levels (MRLs)
123
The ATSDR Minimal Risk Levels (MRLs) were developed as an initial response to
Congressional mandate. Following discussions with scientists within the Department of
Health and Human Services (HHS) and the EPA, ATSDR chose to adopt a practice similar to
that of the EPA's Reference Dose (RfD) and Reference Concentration (RfC) for deriving
substance-specific health guidance levels for non-neoplastic endpoints. An MRL is an
estimate of the daily human exposure to a hazardous substance that is likely to be without
appreciable risk of adverse noncancer health effects over a specified duration of exposure.
These substance-specific estimates, which are intended to serve as screening levels, are
used by ATSDR health assessors and other responders to identify contaminants and
potential health effects that may be of concern at hazardous waste sites. It is important to
note that MRLs are not intended to define clean-up or action levels for ATSDR or other
Agencies.
During the development of toxicological profiles, MRLs are derived when ATSDR determines
that reliable and sufficient data exist to identify the target organ(s) of effect or the most
sensitive health effect(s) for a specific duration for a given route of exposure to the
substance. MRLs are based on noncancer health effects only and are not based on a
consideration of cancer effects. Inhalation MRLs are exposure concentrations expressed in
units of parts per million (ppm) for gases and volatiles, or milligrams per cubic meter
(mg/m3) for particles. Oral MRLs are expressed as daily human doses in units of milligrams
per kilogram per day (mg/kg/day). Radiation MRLs are expressed as external exposures in
units of millisieverts.
ATSDR uses the no-observed-adverse-effect-level/uncertainty factor (NOAEL/UF) approach
to derive MRLs for hazardous substances. They are set below levels that, based on current
information, might cause adverse health effects in the people most sensitive to such
substance-induced effects. MRLs are derived for acute (1-14 days), intermediate (>14-364
days), and chronic (365 days and longer) exposure durations, and for the oral and inhalation
routes of exposure. Currently MRLs for the dermal route of exposure are not derived
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because ATSDR has not yet identified a method suitable for this route of exposure. MRLs
are generally based on the most sensitive substance-induced end point considered to be of
relevance to humans. ATSDR does not use serious health effects (such as irreparable
damage to the liver or kidneys, or birth defects) as a basis for establishing MRLs. Exposure
to a level above the MRL does not mean that adverse health effects will occur.
Proposed MRLs undergo a rigorous review process. They are reviewed by the Health
Effects/MRL Workgroup within the Division of Toxicology; and expert panel of external peer
reviewers; the agency wide MRL Workgroup, with participation from other federal agencies,
including EPA; and are submitted for public comment through the toxicological profile public
comment period. Each MRL is subject to change as new information becomes available
concomitant with updating the toxicological profile of the substance. MRLs in the most recent
toxicological profiles supersede previously published levels. To date, 120 inhalation MRLs,
189 oral MRLs and 6 external radiation MRLs have been derived, (description from website)
Agency for Toxic Substances and Disease Registry
Dr. Selene Chou
Division of Toxicology
Agency for Toxic Substances and Disease Registry
1600 Clifton Road, Mailstop E29
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Atlanta, Georgia 30333Telephone: 404-498-0705
E-Mail: cjc3@cdc.gov
Name, CASRN, MRL (chronic, intermediate, acute)
This source is considered relevant for the CCL Universe because it contains data elements
(MRL) derived from toxicological studies.
It meets considerations because it is peer reviewed.
These data are also represented in the ATSDR Toxicological Profiles; however, these data
are tabular while the Profiles are monographic.
This source meets retrievability criteria because it is in tabular format.
http://www.atsdr.cdc.gov/mrls.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
ATSDR Toxicological Profiles
210
By Congressional mandate, the Agency for Toxic Substances and Disease Registry
(ATSDR) produces "toxicological profiles" for hazardous substances found at National
Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of
occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles
are developed from a priority list of 275 substances. ATSDR also prepares toxicological
profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on
substances related to federal sites.
So far, 269 toxicological profiles have been published or are under development as "final" or
"drafts for public comment"; 250 profiles were published as finals; 106 profiles have been
updated. Currently, 10 profiles are being revised based on public comments received and
one profile is being developed as a public comment draft.
Note: We have data from Tox Profiles that we downloaded and data from ERG EDPSD.
(description from website)
Agency for Toxic Sutstances and Disease Registry; an agency of the U.S. Department of
Health and Human Services (DHHS), Centers for Disease Control (CDC)
Division of Toxicology, Agency for Toxic Substances and Disease Registry
1600 Clifton Road, Mailstop E-29, Atlanta, GA 30333
Phone 404-498-0160
Fax 404-498-0094
Name, CASRN, synonyms, trade names, structure, ID numbers, MW, color, physical state,
MP, BP, density, odor, solubility, log Kow, log Koc, VP, HLC, pKa, hydrolysis rate constant,
autoignition temp, flashpoint, flammability limits, explosive limits, critical effect, MRLs,
NOAEL, "less serious" and "serious" LOAELs, LDx, LCx, CEL, study-specific data
This source is considered relevant for the CCL Universe because it contains data elements
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Redundancy Explanation
Retrievability Explanation
Source URL
from toxicological studies and information on production, which may indicate potential
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.atsdr.cdc.gov
Data Source Name
AwwaRF Project Reports
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
243
Project reports (AVWVA)
AwwaRF
Awwa Research Foundation
6666 W. Quincy Avenue
Denver, Colorado 80235-3098 USA
Email: info@awwarf.org
Telephone: 303.347.6100
Fax: 303.730.0851
Name, Concentrations (ug/L, mg/L), # Utilities that participated in the project, # States that
detected contaminant
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.awwarf.org
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Bad Bug Book
14
This database of fact sheets contains basic information on foodborne pathogenic
microorganisms and natural toxins. It incorporates information from the U.S. Food & Drug
Administration (FDA), CDC, USDA Food Safety Inspection Service, and the National
Institutes of Health (NIH). Pathogens covered include over 40 bacteria, viruses, parasites,
and natural toxins. While not intended to be comprehensive, basic information includes
characteristics, habitat or source, associated foods, infective dose, characteristic disease
symptoms, complications, recent and/or major outbreaks, and any susceptible populations.
(description from website)
FDA - Center for Food Safety and Applied Nutrition
FDA
Center for Food Safety and Applied Nutrition
Outreach and Information Center
5100 Paint Branch Parkway HFS-555
College Park, MD 20740-3835
Toll-Free Information Line:
1-888-SAFEFOOD
(1-888-723-3366)
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
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Redundancy Explanation
Retrievability Explanation
Source URL
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is one of the sources administered by CSFAN (source 231).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://vm.cfsan.fda.aov/~mow/intro.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Base de Dados Tropical (BDT)
15
BDT is a searchable database of biological organisms cataloged in Brazilian laboratories,
including viruses, bacteria, and protozoa. The database lists laboratories that maintain
strains, and contact information for those laboratories.
Andre Tosello Foundation (a Brazilian NGO)
BDT - Base de Dados Tropical
Rua Latino Coelho, 1301
13087-010 Campinas SP
phone: (19)3242-7022
fax: (19)3242-7022
Laboratories that maintain strains, contact information for those laboratories
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.bdt.fat.org.br/index
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Sergey's Manual of Systematic Bacteriology
16
This manual is intended as a guide for treatments and ecological information on identified
bacteria, organized along phylogenetic lines. The website also contains links to many other
databases and resources.
Michigan State University; Sergey's Manual Trust
Denise Searles
searles@pilot.msu.edu
Sergey's Manual Trust
Department of Microbiology and Molecular Genetics
Michigan State University
East Lansing, Michigan 48824-1101
(517) 432-2457
(517) 432-2458 (fax)
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
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Source URL
http://www.cme.msu.edu/berqevs/
Data Source Name
Identification Number
Data Source Description
Biennial Reporting System
272
BRS is a national level system of data collection on the generation, management, and
minimization of hazardous wastes. BRS captures detailed data on the generation of
hazardous waste from large quantity generators and data on the waste management
practices from treatement, storage and disposal facilities in the United States. These data
are collected every other year and provide the ability to perform trend analyses.
SUBJECT COVERAGE:
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Facility Location and Identification Data
Handler Classification & Contact Information
Waste Code and Information
Off-Site and On-Site Management Information
User Comments on Generated and Reported Waste
Description of Reported Waste
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Facility Location and Identification Data, Handler Classification & Contact Information,
Waste Code and Information, Off-Site and On-Site Management Information, User
Comments on Generated and Reported Waste, Description of Reported Waste
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/brs.htm
Data Source Name
Identification Number
Data Source Description
BIOBUSINESS Biological Abstracts Database
17
BioBusiness® provides current and retrospective information to business executives,
financial analysts, product development and marketing professionals, and information
specialists about the business applications of biological and biomedical research. The
database covers the economic aspects of all life sciences areas. Five hundred technical and
business journals, magazines, newsletters, meeting proceedings, U.S patents, and books
from all over the world were scanned for relevant articles. BioBusiness is no longer being
updated. More than 1,100 technical and business journals, magazines, newsletters, meetings
Proprietor
Contact Information
proceedings, and books from around the world are scanned for articles relevant to the
subject coverage of the file, (description from website)
Thomson Dialog
BIOSIS
User Communications Group
2100 Arch Street
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Philadelphia, PA 19103-1399
Telephone: 215-587-4847 (Worldwide)
800 Line: 800-523-4806 (U.S. except AK, HI, PA)
Fax:215-587-2016
E-Mail: info@mail.biosis.org
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://librarv.dialoq.com/bluesheets/html/bl0285.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Biological Sciences - Cambridge Scientific Abstracts
18
This interdisciplinary database offers abstracts and citations to a wide range of research in
biomedicine, biotechnology, zoology and ecology, and some aspects of agriculture and
veterinary science. Supporting over two dozen areas of expertise, this CSA database
provides access to literature from over 6000 serials, as well as conference proceedings,
technical reports, monographs and selected books and patents, (description from website)
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax: +1 301-961-6720
Email: sales@csa.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Source URL
http://www.csa.com/csa/ids/databases-collections.shtml - environmental
Data Source Name
Identification Number
Data Source Description
BIOSIS Biological Abstracts and BIOSIS Previews
19
BIOSIS Biological Abstracts is "the most comprehensive collection of bibliographic
references to life science journal literature published internationally." BIOSIS Previews is a
bibliographic database including international literature sources on biological and biomedical
topics. The BIOSIS sources have nearly 13 million bibliographic records available, compiled
from 5,000 or more scientific journals, technical reports, meetings, reviews, books,
monographs, and file data, from 1969 to the present. Relevant subject coverage includes
biochemistry, biophysics, environmental biology, microbiology, pathology, pharmacology,
and toxicology, (description from website)
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
BIOSIS
Thomson
3501 Market Street
Philadelphia, PA 19104 USA
phone: 1-800-336-4474 (USA and Canada)
215-386-0100 (Worldwide)
fax:215-243-2208
e-mail: info@biosis.org
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.biosis.org/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Bugs
20
The Bugs program was designed to help medical students learn basic microbiology and
pathogenesis in a clinical context. It is based on the Bugs database, containing information
on 159 pathogens — the diseases they cause, the signs and symptoms of the diseases, the
source of the organism, sites where it is normal and sites where it is pathogenic, virulence
mechanisms, diagnostic factors, treatment, and prevention, (description from website)
University of Florida College of Medicine
For information on using this program contact Donna Duckworth Phd.
duckwort@mgm.ufl.edu
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://medinfo.ufl.edu/vear2/mmid/bms5300/bugs/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
CAB Abstracts - CABI Publishing
21
CAB Abstracts is CABI Publishing's main database, for the applied life sciences. It covers
research and development literature in the fields of agriculture, forestry, aspects of human
health, human nutrition, animal health and the management and conservation of natural
resources.
CAB Abstracts contains over 4 million records from 1973 to present, with over 180,000 new
records added each year. CAB Abstracts is available through a variety of third party
vendors, including Ovid, ISI, EBSCO, Dialog, DIMDI, STN, BIDS and CAB Direct.
(description from website)
CABI Publishing
CABI Publishing North America
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
875 Massachusetts Avenue,
7th Floor, Cambridge,
MA 02139, USA
Email: cabi-nao@cabi.org
Tel: +1 6173954056
Toll free: +1 800 528 4841
Fax:+1 6173546875
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cabi-publishina.org/Products/Database/Abstracts/lndex.asp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
California Department of Pesticide Regulation (CDPR)
235
State monitoring program list and links to reports (AWWA)
List of registered active ingredients and product counts.
http://www.cdpr.ca.gov/docs/label/actai.htm
California Department of Pesticide Regulation
John Stutz
Phone:(916)324-3906
email: jstutz@cdpr.ca.gov
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, number of products used in
This source is considered relevant for the CCL Universe because it contains a list of
bioactive compounds.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.cdpr.ca.gov/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
CANCERLIT
22
CANCERLIT is a bibliographic database including source information from biomedical
journals, proceedings, books, reports, and doctoral theses. The database contains over 1.5
million citations and includes references to cancer literature published from the 1960s to the
present. The database is focused on biomedical aspects of cancer literature, (description
from website)
National Cancer Institute; a component of NIH, within the DHHS
NCI Public Inquiries Office
Suite 3036A
6116 Executive Boulevard, MSC8322
Bethesda, MD 20892-8322
1-800-4-CANCER (1-800-422-6237)
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cancer.gov/cancerinfo/literature
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Carcinogenic Potency Project (CPP)
23
The Carcinogenic Potency Database (CPDB) is a systematic and unifying analysis of
animal cancer tests. It standardizes the published literature and creates an easily accessible
research resource that can be and has been used to address a wide variety of research and
regulatory issues in carcinogenesis. A measure of carcinogenic potency, TD50 (tumorigenic
dose-rate for 50% of experimental animals), is estimated for the tumor incidence at each site
for which results are reported in the database. The CPDB includes results reported in 1383
papers in the general literature through 1996 and 421 Technical Reports of the National
Cancer Institute/National Toxicology Program (NCI/NTP) through 1998. Results are
examined for 6008 experiments on 1451 chemical agents; these are displayed in a plot
format organized by chemical name. Detailed information that is important in the
interpretation of bioassays, is reported on each experiment, (whether positive or negative for
carcinogenicity) including: qualitative information on strain, sex, target organ, histopathology
and author's opinion, as well as quantitative information on carcinogenic potency, statistical
significance, tumor incidence, dose-response curve shape, length of experiment, dose-rate,
and duration of dosing. Each set of experimental results references the original published
paper. A word of caution is necessary about the limitations of the database. No attempt has
been made to evaluate whether or not a compound induced tumors in any given experiment;
rather, the opinion of the published authors is presented as well as the statistical significance
of the TD50 calculated from their results. Moreover, the database contains only long-term
tests which fit a set of criteria designed to measure potency, and therefore does not cover
all cancer tests. (From the CCP's website: http://potency.berkeley.edu/text/methods.html)
Lawrence Berkeley Laboratory
Carcinogenic Potency Database
Mail Stop: 946
1 Cyclotron Road
Name, CASRN, administered dose, TD50 (tumorigenic dose), tumor type, 99% Cl on TD50
This source is considered relevant for the CCL Universe because it contains data on
carcinogenicity from toxicological studies.
It meets considerations because it is peer reviewed.
This source is redundant with DSSTox (source 53).
This source meets retrievability criteria because it is in tabular format.
http://potencv.berkelev.edu/cpdb.html
Data Source Name
Identification Number
Data Source Description
Case/MCase/MC4PC
238
The MCASE program will accept the structure of a series of diverse compounds and their
observed activity (quantitative or qualitative) in a biological test performed under a common
protocol. The program will automatically evaluate the data set and try to identify the
structural features responsible for activity (biophores). It then creates organized dictionaries
of these biophores and develops ad hoc local QSAR correlations that can be used to predict
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Contact Information
the activity of unknown molecules.
Upon entering a new molecule, the MCASE program will evaluate it against the dictionary and
the appropriate QSARs it has created and, based on the results, venture a prediction as to
the projected activity of the molecule in the corresponding test. All conclusions can be
documented and rationalized by querying the program. If the activity of the molecule is
known, its observed value will also be displayed.
This program is particularly useful in drug design, when the user intends to analyze
proprietary information and create its own dictionaries. It can also accept the databases
offered in conjunction with the CASETOX program, (description from website)
Multicase
Prof. Gilles Klopman, President & CEO
e-mail: klopman@multicase.com
phone: (216)831-3740
fax: (216)831-3742
Mailing Address:
MULTICASE Inc.
23811 Chagrin Blvd. Ste 305
Beachwood, OH 44122
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Unknown
This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.
It does not meet considerations because no information on type of data elements is
available.
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a
http://www.multicase.com/products/prod01.htm
Data Source Name
Identification Number
Data Source Description
Center for Food Safety and Applied Nutrition (CFSAN)
231
CFSAN, in conjunction with the Agency's field staff, is responsible for promoting and
protecting the public's health by ensuring that the nation's food supply is safe, sanitary,
wholesome, and honestly labeled, and that cosmetic products are safe and properly labeled.
The Center's primary responsibilities include:
-the safety of substances added to food, e.g., food additives (including ionizing radiation)
and color additives
- the safety of foods and ingredients developed through biotechnology
- seafood Hazard Analysis and Critical Control Point (HACCP) regulations
- regulatory and research programs to address health risks associated with foodborne
chemical, and biological contaminants
- regulations and activities dealing with the proper labeling of foods (e.g., ingredients,
nutrition health claims) and cosmetics
- regulations and policy governing the safety of dietary supplements, infant formulas, and
medical foods
- safe and properly labeled cosmetic ingredients and products
- food industry postmarket surveillance and compliance
- consumer education and industry outreach
- cooperative programs with state and local governments
- international food standard and safety harmonization efforts
Some of CFSAN's current areas of food safety concern are:
- biological pathogens
- naturally occurring toxins
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Contact Information
Type of Data Elements
- dietary supplements
- pesticide residues
- toxic metals
- decomposition and filth
- food allergens
- nutrient concerns
- dietary components
- radionuclides
- TSE-type diseases
- product tampering
(description from website)
FDA - Center for Food Safety and Applied Nutrition
FDA
Center for Food Safety and Applied Nutrition
Outreach and Information Center
5100 Paint Branch Parkway HFS-555
College Park, MD 20740-3835
1-888-SAFEFOOD (1-888-723-3366)
Data elements for microbial contaminants, food additives, and contaminants that are found
in food
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://vm.cfsan.fda.gov
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemfinder
29
Chemfinder is a chemical database that also incorporates a web search for locating chemical
information such as CAS registry numbers, molecular formulas and structures, and some
physical property information. It also provides a list of indexed web sites on chemical
information in categories like health, biochemistry, and physical properties during a search
for information on any given chemical, (description from website)
CambridgeSoft Corporation
CambridgeSoft Corporation
100 CambridgePark Drive
Cambridge, MA 02140 USA
Tel 1 800 315-7300 /1 617 588-9300
Fax 1 617588-9390
email: info@chemfinder.com
Name, Synonyms,Formula, CAS RN, Water Solubility, Links to other websites with
information about the compound in the categories: Biochemistry, Physical Properties,
Usage, Health, Regulations, Misc, MSDS, Structures, Pesticides/Herbicides, Trading
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://chemfinder.cambridgesoft.com/
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Chemical Backgrounder
30
The U.S. National Safety Council (NSC) publishes a series of Chemical Backgrounders,
which contain data on over 80 regulated chemicals. The Chemical Backgrounders give a
brief synopsis of physicochemical properties, usage, manufacturers, regulations, and health
effects, (description from website)
National Safety Council
National Safety Council
1121 Spring Lake Drive
Itasca, IL 60143-3201
(630)285-1121
(630) 285-1315 fax
info@nsc.org
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retries ability Explanation
Source URL
Description, Chemical and physical properties, Identification, Health effects, Exposure
Values, Economics, Regulation, National Overview of 1998 Toxics Release Inventory
This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nsc.org/librarv/chemical/chemical.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Chemical Carcinogenesis Research Information System (CCRIS)
24
CCRIS is a toxicology data file of the National Library of Medicine's (NLM) Toxicology Data
Network (TOXNET®). It is a scientifically evaluated and fully referenced data bank,
developed and maintained by the National Cancer Institute (NCI). It contains over 8000
chemical records with carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition
test results. Data are derived from studies cited in primary journals, current awareness tools,
NCI reports, and other special sources. Test results have been reviewed by experts in
carcinogenesis and mutagenesis. A useful feature is that searching for one substance will
produce information for other substances which are relevant. For example, a search for
acetone will bring up isopropanol, because acetone is one of its metabolites, (description
from website)
National Library of Medicine; NIH; developed and maintained by NCI
CCRIS Representative
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone (301)496-1131
FAX: (301)480-3537
e-mail: toxmail@toxnetmail.nlm.nih.gov
URL: http://sis.nlm.nih.gov
Major Use, Administrative Information, Mutagenicity Study, Carcinogenicity Study,
Tumor Promotion, Tumor Inhibition
This source is considered relevant for the CCL Universe because it contains the results of
carcinogenicity and mutagenicity studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
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Source URL
automated retrieval.
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7CCRIS
Data Source Name
Identification Number
Chemical Evaluation Search and Retrieval (CESARS) - CCOHS
28
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
The CESARS database contains information on chemicals, including health effects in
humans, mammals, and aquatic and plant life; also covers data on physicochemical
properties, and environmental fate and transport. Includes a total of 850 chemical profiles,
each containing data on up to 23 topic areas drawn from authoritative reviews focusing on
toxicological and environmental investigations into toxicity, transformation processes,
bioaccumulation, bioconcentration, transport carcinogenicity, mutagenicity, and reproductive
toxicity. (description from website)
Canadian Center for Occupational Health and Safety (CCOHS)
clientservices@ccohs.ca
1-800-668-4284 (Canada and USA)
1-905-570-8094
1-905-572-2206 (FAX)
Properties - Physical and Chemical: Molecular formula, molecular weight, physical state,
melting point, boiling point, flash point, autoignition point, explosive limits, density, specific
gravity, Henry's law constant, pKa, TOD, BOD, COD, conversion factor, odor threshold air,
water and taste, aqueous solubility, vapor pressure, and n-octanol/water partition coefficient.
Regulations and Guidelines: US, Canadian and International data pertaining to acceptable
levels in the environment, waste disposal requirements, health and safety guidelines,
labelling and transportation is included. Manufacture: Uses, occurrence, production and
methods of synthesis. Acute Toxicity - Terrestrial animals/ Human/ Aquatic animals:
Adverse effects such as LD50 or LC50 for test exposures to animals, adverse effects to
humans by test compounds; toxicity studies on freshwater aquatic species such as LC50 or
EC50; all undertaken in short term tests. Chronic Toxicity - Terrestrial animals/ Humans/
Aquatic animals: Toxicity studies undertaken in medium to long term time frames, such as
NOAELs (No Observed Adverse Effect Levels), MATC (Maximum Adverse Toxicant
Concentration), etc. Phytotoxicity: Information on effects of substances to aquatic and
terrestrial plants. Carcinogenicity: Summaries of studies conducted by NCI/NTP, IARC,
NIOSH, EPA. Mutagenicity: Effects are reported such as gene mutations, chromosomal
aberrations and DMA damage. Reproductive and Developmental Effects: Reports of
chemical effects on terrestrial animals or humans are reported. NOAELs may be provided if
available. Other Adverse Effects: Other effects which may be reported such as aesthetic
effects. Pharmacokinetics/Metabolism: Uptake, distribution, biotransformation and
elimination in animals. Bioaccumulation/Bioconcentration: Bio-uptake of chemicals in aquatic
organisms. Transport Processes: Transport of chemicals in the environment including
sorption to matter in water, air, soil, sediment or biota (flora and fauna) and volatilization
from water or soil.
General Fate Processes: Reports on studies predicting the fate of chemicals in the
environment. Transformation Processes: Biodegradation by microorganisms and hydrolysis
of compounds. Analysis and Treatment: Standard analytical techniques plus water or waste
treatment methods, if available.
References: Ontario Environmental Assessment: The Ontario Ministry of the Environment
assessment and scoring of the chemical.
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.ccohs.ca/products/databases/cesars.html
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Data Source Name
Identification Number
Data Source Description
Chemical Hazard Response Information System
285
CHRIS provides information needed to respond to emergencies that occur during the
transport of hazardous chemicals. It also provides information that can be used to design
safety procedures aimed at preventing emergency situations. While geared toward
chemicals transported over water, this information can be useful for a wide range of
chemical emergency situations.
SUBJECT COVERAGE:
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemical/Physical Property Data
Health and Fire Hazard Data
Hazard Classification Data
Labeling Information
Reactivity Data
Water Pollution Data
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Chemical/Physical Property Data, Health and Fire Hazard Data, Hazard Classification Data,
Labeling Information, Reactivity Data, Water Pollution Data
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/chris.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemical Information System (CIS) - ILO/OSHIC
36
Database is no longer available through INCHEM. Does not appear to be available through
ILO web site.
International Labour Organisation Occupational Safety and Health Information Centre
N/A
Not applicable
This source is no longer available online.
This source is no longer available online.
This source is no longer available online.
This source is no longer available online.
http://www.inchem.org/paaes/ilodb.html
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Data Source Name
Identification Number
Chemical Registry System (CRS)
42
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
CRS is part of a single meta-data registry of EPA information sources, and provides
information on 70,161 chemical substances, including representation in EPA regulations as
well as data systems. Results of a search may also include links to other information
sources on the chemical database. Ninety-three sources are checked from 23 submitting
organizations. Substance files include the following sections: chemical synonyms, a list of
regulations applicable to the chemical and other regulatory information, health effects
sources for the queried chemical, and information about the general group of chemicals.
(description from website)
EPA, Office of Environmental Information
Michael Pendleton
United States Environmental Protection Agency
Office of Environmental Information
1200 Pennsylvania Avenue, NW
Mail Code 2822-T
Washington, DC 20460
pendleton.michael@epa.gov
Phone: (202)566-1658
Fax:(202)566-1639
CAS RN, Classification, Molecular Formula, Molecular Weight, Regulatory Resources
Other Sources, Group/Component, Related Links
This source is considered relevant for the CCL Universe because it is an interface to other
information in EPA's SRS system.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of Substance Registry System
(SRS) (source 203).
This source meets retrievability criteria because it is in tabular format.
http://www.epa.gov/srs/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Chemical Toxicity Database - Ministry of Health and Welfare, Japan
31
Japan has been studying chemical toxicity under the initiative of the National Institute of
Health Sciences and has also been performing safety tests of existing chemicals with high
production volume (HPV) in cooperation with the U.S., the EC, and other OECD member
countries as one of the OECD Chemicals programme Group members since 1991. These
data being generated are very important to ensure chemical safety. Furthermore common
utilization of the data among the member countries facilitates global enforcement of safety
programmes.
Toxicity studies conducted for individual environmental chemicals include a single dose
toxicity test, a 28-day repeat dose toxicity test, a reproductive/development toxicity test
and mutagenicity tests. Each test has various practical and academic contents such as
animal species, dose, test method and types of toxicity appearance. The results are
intended for publication as academic report documents.
(description from website)
Ministry of Health and Welfare, Japan
Ministry of Health, Labor, and Welfare
1-2-2 Kasumigaseki Chiyoda-ku Tokyo
100-8916 Japan
03-5253-1111
www-admin@mhlw.go.jp
Name, CASRN, formula, LD50, NOEL, mutation data
Relevance Explanation
This source is considered relevant for the CCL Universe because it contains data elements
(LD50, NOEL) from toxicological studies.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://wwwdb.mhlw.ao.ip/ginc/html/db1.html
Data Source Name
Identification Number
Data Source Description
Chemical Update System (CDS)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
32
"The Chemical Update System (CUS) contains confidential data reported by industry
(approximately 1200 companies) as a partial update of the Toxic Substances Control Act
(TSCA) Inventory. Manufacturers and importers are required to report company information
(plant site name, address, Data Universal Numbering System (DUNS) number) and chemical
information (CAS registry number, Premanufactures Number (PMN)/Bonafide/Test
Marketing Exemption Application (TMEA) or Confidential Chemicals Identification (CCID)
System Assession Number, and production volume) for chemicals they manufactured or
imported in excess of 10,000 pounds in the immediately preceding fiscal year." (description
from website)
EPA OPPT
Office of Prevention, Pesticides, and Toxic Substances, Pollution Prevention and Toxics,
Records and Dockets Management Branch
Contact: Darryl Ballard
Mail Code: 7407
Telephone: 202-564-8958
Production Volume
This source is considered relevant for the CCL Universe because it contains information on
production volume, which may indicate potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with CUS/IUR (source 33).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval. This source is retrievable through CUS/IUR.
http://www.epa.aov/records/policv/schedule/sched/273.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Chemical Update System/Inventory Update Rule (CUS/IUR)
33
"The Chemical Update System (CUS) contains confidential data reported by industry
(approximately 1200 companies) as a partial update of the Toxic Substances Control Act
(TSCA) Inventory. Manufacturers and importers are required to report company information
(plant site name, address, Data Universal Numbering System (DUNS) number) and chemical
information (CAS registry number, Premanufactures Number (PMN)/Bonafide/Test
Marketing Exemption Application (TMEA) or Confidential Chemicals Identification (CCID)
System Assession Number, and production volume) for chemicals they manufactured or
imported in excess of 10,000 pounds in the immediately preceding fiscal year." (description
from website)
EPA
Contact Information
Type of Data Elements
Relevance Explanation
Darryl Ballard
RDMB
202-564-8958
ballard.daryll@epa.gov
Production Volume
This source is considered relevant for the CCL Universe because it contains information on
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
production volume, which may indicate potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/oppt/iur/iur02/search03.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemicals in Commerce Information System (CICIS) - Toxic
Substances Control Act Inventory
283
The Toxic Substances Control Act (TSCA) of 1976 requires the Environmental Protection
Agency (EPA) to maintain a list of chemical substances that have been manufactured,
imported, or processed in the United States for commercial purposes since January 1, 1975.
The TSCAINV database contains this list and is commonly referred to as the TSCA
Inventory. Note that the database contains only the public portion of the Inventory; a
supplemental, "confidential" portion of the Inventory is maintained by EPA.
SUBJECT COVERAGE:
CAS Registry Number
Chemical Name Identification
TSCA Status
(description from website)
National Information Services Corporation (NISC)/EPA
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Name, CASRN, TSCA Status
This source is considered relevant for the CCL Universe because it is a list of chemicals in
production.
It meets considerations because it meets all NDWAC minimum data requirements.
The source is redundant with TSCA.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/tscainv.htm
Data Source Name
ChemlDplus - Chemical Identification Plus
Identification Number
Data Source Description
34
ChemlDplus contains one record per chemical substance for over 368,000 compounds cited
in the National Library of Medicine (NLM) databases residing on either the ELHILL® or the
TOXNET® system. The data elements include: CAS registry numbers, molecular formulas,
systematic names, synonyms, MeSH® headings, name and formula fragments, and list and
file locator designations. Along with that information, ChemlDplus lists many links to
information in other databases for a chemical, including all NLM databases and many others:
CCRIS, Developmental and Reproductive Toxicology/ Environmental Teratology
Information Center (DART/ETIC), Gene-Tox, Hazardous Substances Data Bank (HSDB)
Structures, Integrated Risk Information System (IRIS), NCI-3D, Toxline, and the Toxics
Release Inventory (TRI). ChemlDplus contains molecular structures for 206,098 of the
chemicals in the database.
ChemlDplus is searchable by Name, Synonym, CAS Registry Number, Molecular Formula,
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Classification Code, Locator Code, and Structure, (description from website)
National Library of Medicine; Division of Specialized Information Services, NIH
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301)496-1131
e-mail: tehip@teh.nlm.nih.gov
Name, CASRN, molecular formula, database listings
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://chem.sis.nlm.nih.gov/chemidplus/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Clinical Virology
37
New edition of a reference that informs scientists and health care professionals about the
medically relevant aspects of this rapidly evolving field. The 56 contributions by experts in
their respective specialties, incorporating the latest developments and relevant citations to
address infections and syndromes related to particular organ systems; the fundamentals of
modern medical virology including immune responses and vaccinology, diagnostics,
antivirals, and gene therapy; and the virology, epidemiology, pathogenesis, clinical
manifestations, laboratory diagnosis, and prevention and treatment of important specific
human viral pathogens. Edited by Richman (pathology and medicine, U. of California),
Richard J. Whitley (infectious diseases, U. of Alabama) and Frederick G. Hayden (internal
medicine and pathology, U. of Virginia School of Medicine).
Book News, Inc.®, Portland, OR
(description from Amazon.com)
Richman, Whitely, Hayden, editors. 2002. Churchill Livingstone, publishers
Douglas D. Richman, MD
VA San Diego Healthcare System
University of California San Diego
Departments of Path & Med, 0679
9500 Oilman Drive
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
Error! Hyperlink reference not valid.
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Communicable Disease Report (CDR) - United Kingdom
25
The CDR Weekly is an electronic bulletin that is published each Thursday. It has been
electronic since 2001, and was published as an open circulation bulletin from 1991 onwards.
It comprises a weekly section of public health news and other pages of routine
microbiological and epidemiological data and reports, which are updated on a monthly basis
(ie, reports by Infections). They include: Enteric, Respiratory, Immunisation, HIV and STIs,
Bacteraemia, Zoonoses, Travel Health, Primary Care. Each section has a comprehensive
archive of all relevant articles and data published in the current year. PDF files of back
copies are available from 1991 onwards on the back issues page, (description from website)
U.K. Health Protection Agency
Communicable Disease Report Weekly
Information Knowledge Management Dept.
61 Colindale Avenue
London, NW9 5DF
United Kingdom
Telephone +44 (0)20 8200 1295
Fax+44 (0)20 8358 3130
email: neil.hough@hpa.org.uk
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.hpa.org.uk/cdr/default.htm
Data Source Name
Communicable Disease Reports (CDR) - Australia
Identification Number
Data Source Description
Proprietor
245
The Surveillance and Epidemiology Section of the Population Health Division (PHD) is the
Commonwealth's primary data collection and coordination centre for many communicable
diseases. The PHD also coordinates and contracts other agencies to collect data and/or
conduct research on communicable diseases. Two such centres are the National Centre in
HIV Epidemiology and Clinical Research (NCHECR) and the National Centre for
Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS).
National surveillance networks and centres facilitate early detection of disease as well as
long-term epidemiological analysis. These in turn provide essential information for planning
interventions, and form the foundation for future public health priorities and clearly focused
evidence-based policy development and best practice. This philosophy is reflected in work
carried out or co-ordinated through the PHD. As part of the National Communicable Diseases
Surveillance Strategy, States/Territories and the Commonwealth are improving current
surveillance systems to build the capacity and infrastructure for future nationally consistent
surveillance systems which will deliver more comprehensive data for all communicable
diseases of public health significance.
Surveillance data is disseminated through the quarterly publication Communicable Diseases
Intelligence (GDI). GDI publishes occasional reports on some national surveillance schemes,
including the National Myco bacteria I Surveillance System, the Australian Mycobacterial
Reference Laboratory Network, the National Neisseria Network, OzFoodNet, Rotavirus
surveillance and the Sentinel Chicken Scheme. Information on national surveillance schemes
routinely reported in GDI are detailed in the document Surveillance systems reported in
GDI. (description from website)
Australian Government
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Communicable Diseases Intelligence
Surveillance and Epidemiology Section
Population Health Division
MDP 14
PO Box 9848
Canberra ACT, 2601
Telephone: +61 2 6289 8245
Facsimile: +61 2 6289 7791
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.health.aov.au/pubhlth/strateg/communic/index.htm
Data Source Name
Identification Number
Data Source Description
Compendium of Pesticide Common Names
255
For purposes of trade, registration and legislation, and for use in popular and scientific
publications, pesticides need names that are short, distinctive, non-proprietary and widely-
accepted. Systematic chemical names are rarely short and are not convenient for general
use, and so standards bodies assign common names to the active ingredients of pesticides.
More than 1000 of these official pesticide names have been assigned by the International
Organization for Standardization (ISO).
This Compendium is believed to be the only place where all of the ISO-approved standard
names of chemical pesticides are listed. It also includes approved names from national and
Proprietor
Contact Information
Type of Data Elements
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
international bodies for pesticides that do not have ISO names, (description from website)
Alan Wood (http://www.hclrss.demon.co.uk/demos/alan_wood.html)
Alan Wood
Context Limited
Grand Union House
20 Kentish Town Road
London
NW1 9NR
United Kingdom
Telephone: 020 7267 8989
Name (common, IUPAC), CASRN, molecular formula, structure
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source meets retrievability criteria because it is in HTML format and can be extracted in
tabular format.
http://www.hclrss.demon.co.uk/
Data Source Name
Comprehensive Environmental Response, Compensation, and
Liability Information System (CERCLIS)
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Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
38
This database allows a user to access administrative and geographic information about all
Superfund sites around the country. Users can access maps for each facility, which
display sites of discharges to water, hazardous waste containment, and toxic/air releases, as
well as site assessment and remediation information, (description from website)
EPA Envirofacts Data Warehouse and Applications
enviromail@epamail.epa.gov
Facility Information, Site Name, Address, County, Site SMSA, Federal Facility, NPL Status,
Corporate, Mapping Info, Record of Decision (ROD) Info, EPA Regional, Latitude, Longitude,
Ownership, Site, Incident, Action, Responsibility, Planned Outcome, Urgency
This source is considered relevant for the CCL Universe because it contains information on
potential contaminant occurrence at superfund sites.
It meets considerations because it is peer reviewed.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/enviro/html/cerclis/cerclis auerv.html
Data Source Name
Identification Number
Computer Retrieval of Information on Scientific Projects
276
Data Source Description
CRISP is a searchable database of federally funded biomedical research projects conducted
at universities, hospitals, and other research institutions. The database, maintained by the
Office of Extramural Research at the National Institutes of Health (NIH), includes projects
funded by NIH, Substance Abuse and Mental Health Services Administration (SAMHSA),
Health Resources and Services Administration (HRSA), Food and Drug Administration
(FDA), Centers for Disease Control and Prevention (CDC), Agency for Healthcare Research
and Quality (AHRQ), and Office of Assistant Secretary of Health (OASH). Users can
search for scientific concepts, emerging trends and techniques, or identify specific projects
and/or investigators. The database currently includes records from between 1992 and 2000.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
SUBJECT COVERAGE:
Project Title and Abstract
Indexing Terminology
Name(s) of Investigator(s)
Sponsoring Institution(s)
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com/cis/details/crisp.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Concise International Chemical Assessment Documents (CICADs)
35
CICADs are the latest in a family of publications from the International Programme on
Chemical Safety (I PCS) - a cooperative programme of the World Health Organization
(WHO), the International Labour Organisation (ILO), and the United Nations Environment
Programme (UNEP). CICADs join the Environmental Health Criteria documents (EHCs) as
authoritative documents on the risk assessment of chemicals. CICADs are concise
documents that provide summaries of the relevant scientific information concerning the
potential effects of chemicals upon human health and/or the environment. They are based
on selected national or regional evaluation documents or on existing EHCs. Before
acceptance for publication as CICADs by IPCS, these documents have undergone
extensive peer review by internationally selected experts to ensure their completeness,
accuracy in the way in which the original data are represented, and the validity of the
conclusions drawn. The primary objective of CICADs is characterization of hazard and dose-
response from exposure to a chemical. CICADs are not a summary of all available data on
a particular chemical; rather, they include only that information considered critical for
characterization of the risk posed by the chemical. The critical studies are, however,
presented in sufficient detail to support the conclusions drawn. For additional information, the
reader should consult the identified source documents upon which the CICAD has been
based. Risks to human health and the environment will vary considerably depending upon
the type and extent of exposure. Responsible authorities are strongly encouraged to
characterize risk on the basis of locally measured or predicted exposure scenarios. To assist
the reader, examples of exposure estimation and risk characterization are provided in
CICADs, whenever possible. These examples cannot be considered as representing all
possible exposure situations, but are provided as guidance only. The reader is referred to
EHC 170 for advice on the derivation of health-based guidance values. While every effort is
made to ensure that CICADs represent the current status of knowledge, new information is
being developed constantly. Unless otherwise stated, CICADs are based on a search of the
scientific literature to the date shown in the executive summary. In the event that a reader
becomes aware of new information that would change the conclusions drawn in a CICAD, the
reader is requested to contact the IPCS to inform it of the new information, (description
from website)
International Programme for Chemical Safety, World Health Organization, International
Labour Organisation, United Nations Environment Programme
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, Formula, synonyms, CASRN, ID numbers, MW, density, BP, MP, water solubility,
other solubility, partition coefficients, Log Koc, Log Kow, VP, HLC, production,
environmental fate, BMC/D, ENEV, IARC cancer class, TC(A), CTV, ECx, ICx, LCx, LDx,
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/cicads.html
Data Source Name
TV) Database
Identification Number
Data Source Description
Contaminant Exposure and Effects - Terrestrial Vertebrates (CEE-
27
CEE-TV is a database of contaminant exposure and effects for terrestrial vertebrates in
inner coastal regions of the Atlantic, Gulf, Pacific, and Alaskan areas of the United States.
The database was created via computerized literature searches, reviews of existing
databases, and integration of unpublished reports from conservation agencies, private
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Contact Information
Type of Data Elements
groups and academic institutions. The database includes summary information on species,
collection date, site location, estuary name, contaminant concentrations, biomarker and
bioindicator responses, and source references. Searches provide a list of compounds,
concentrations of organopesticides, total polychlorinated biphenyls congeners (PCBs),
dioxin-like PCBs, dioxin-like PCB Toxic Equivalent Quotient (TEQ), inorganics,
organophosphorous insecticides, carbamates, and petroleum hydrocarbons. There are
approximately 10,000 references of ecotoxicological exposure and effects information for
over 200,000 individuals representing a total of over 400 vertebrate species residing in
estuaries, (description from website)
Patuxent Wildlife Research Center, U.S. Geological Survey (USGS)
USGS Patuxent Wildlife Research Center
Barnett A. Rattner
12011 Beech Forest Road
Laurel, MD 20708-4041
Phone:(301)497-5671
Fax:(301)497-5675
Email: barnett_rattner@usgs.gov
Family, Year From, State, Latitude, Sample Size, Record No, Order, Year To, Estuary,
Longitude, Genus/Species, Class, Location, HUC, Matrix
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source does not meet relevance criteria because it contains only information on
ecological toxicity.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.pwrc.usas.qov/contaminants-online/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Control of Communicable Diseases Manual; 17 ed.
39
Univ. of California, Berkeley. Brandon/Hill Medical List first-purchase selection (#278).
Previous edition, c1995, was authored by Abram S. Benenson. Pocket-sized manual, in
outline format, providing current information and recommendations for communicable
disease prevention.
(description from Amazon.com)
James Chin, editor, 2000. American Public Health Association
James Chin
Clinical Professor of Epidemiology
School of Public Health, UC Berkeley
456 Kentucky Avenue
Berkeley, California 94707-1735
USA
Tel: 510527 6252
Fax: 510527 7640
E-Mail: jchin@cdpc.com
jchin@socrates.berkeley.edu
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
Error! Hyperlink reference not valid.
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
CrossFire BEILSTEIN
41
CrossFire BEILSTEIN is a comprehensive structure and factual database covering over 8
million compounds and 35 million associated chemical properties and biological activity data
that describes "pharmacodynamics and environmental toxicology, transport, distribution, and
fate." The record contains documents from the BEILSTEIN Handbook of Organic
Chemistry as well as data from 120 peer reviewed journals. Subject coverage includes all
types of physicochemical properties, reaction information, spectral data, structural data, and
pharmacological and ecological data, (description from website)
MDL Information Systems GmbH (formerly known as BEILSTEIN Informations systemme)
MDL Information Systems, Inc.
14600 Catalina Street
San Leandro, CA 94577
TEL: (510)895-1313
FAX: (510) 614-3608
Chemical Name, Effect, Species or Test-System, Route of Application, Kind of Dosing,
Method, Further Details, Results, Half-Life Time; Laboratory Use and Handling; Ecological
Data; Concentration in the Environment; Transport and Distribution; Bioconcentration Factor;
Accumulation Half-life Time; Accumulation Rate Constant; Elimination Half-Life Time;
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.mdl.com/products/knowledge/crossfire beilstein/index.isp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Cumulative Estimated Daily Intake/Acceptable Daily Intake
(CEDI/ADI) Database
26
As part of the premarket notification process for food contact substances (FCSs), the
Office of Food Additive Safety (OFAS) is developing and making publicly available a
database of cumulative estimated daily intakes (CEDIs) and acceptable daily intakes (ADIs)
for a large number of FCSs. This database is referred to as the CEDI/ADI database. At this
time, the database contains CEDI/ADI information on an initial subset of food-contact
substances. OFAS is attempting to collect and review data for approximately 3000 FCSs for
inclusion into the CEDI/ADI database. As additional information becomes available, the
CEDI/ADI database will be updated. The CEDIs and ADIs are based on currently available
information and may be subject to revision on the basis of new information as it is submitted
or made available to OFAS. All potential notifiers are encouraged to approach OFAS with
new information on which to base CEDIs and ADIs and include such information in
notifications. See Preparation of Food Contact Notifications and Food Additive Petitions for
Food Contact Substances: Chemistry Recommendations. Concerning the database, OFAS
notes the following: The CEDI/ADI values listed at this early stage in the development of the
database are primarily for FCSs that may be classified as adhesives (21 CFR 175.105),
paper and paperboard components (21 CFR 176) and polymer adjuvants and production aids
(21 CFR 178). Information on many polymeric FCSs and constituents, such as monomers,
are presently not available. The CEDI values are expressed as dietary concentration (parts-
per-billion, ppb) and as intake (milligram/kilogram body weight/person/day, mg/kg bw/d) to
facilitate comparison to the applicable ADI value for the FCS. Many of the FCSs listed
below are only regulated for use under 21 CFR 175.105. In the absence of appropriate
information, such as migration studies, on which to base a numerical estimate of exposure,
OFAS assumes a default CEDI of 7 ppb (corresponding to a cumulative intake of 0.00035
mg/kg-bw/d). (description from website)
FDA - Center for Food Safety and Applied Nutrition
Office of Food Additive Safety (HFS-200)
Center for Food Safety and Applied Nutrition
Food And Drug Administration
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Relevance Explanation
5100 Paint Branch Parkway
College Park, MD 20740-3835
(202)418-3100
Name, CASRN, ADI, CEDI, CUM DC
This source is considered relevant for the CCL Universe because it contains health effects
data.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.cfsan.fda.qov/~dms/opa-edi.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Current Contents Search - Life Sciences - ISI
44
ISI® Current Contents/Life Sciences provides access to complete bibliographic information
from articles, editorials, meeting abstracts, commentaries, and all other significant items in
recently published editions of over 1,370 of the world's leading life sciences journals and
books in a broad range of categories.
Key Advantages & Capabilities:
- Helps users stay up-to-date in their research by enabling them to conduct fast,
multidisciplinary searches of the current life sciences literature
- Provides a complete picture of today's global research in the life sciences by combining
comprehensive coverage with numerous access points, exclusive search capabilities, and
optional coverage of past research and proceedings data
- Saves research time by providing one source for a variety of research data including
author abstracts, author addresses, and more information per bibliographic record than in
other resources
(description from website)
Thomson ISI
Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax:+1 2153862911
E-mail: sales@isinet.com
Web: www.thomsonisi.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.isinet.com/cai-bin/irnlst/iloptions.cgi?PC=P
Data Source Name
Database of Sources of Environmental Releases of Dioxin-Like
Compounds in the United States
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Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
46
This database is a "repository of congener specific chlorinated dibenzo-p-dioxin/dibenzofuran
(CDD/CDF) emissions data from all known sources in the United States." Emissions can be
tracked overtime, homologue and congener profiles can be compared between and among
source categories, and source specific emission factors can be used to develop emission
estimates. The two reference years for information in the database are 1995 and 1987, with
data extracted from original test reports. The database covers both facility and non-facility
(e.g. mobiles sources like automobiles area sources) based emission data. Most of the
emissions data concerns releases to air. (description from website)
EPA, ORD
DAVID CLEVERLY
Role: CONTACT
Primary Phone #: 202-564-3238
Primary Email: cleverly.david@epa.gov
Emmissions, Release to Air
This source is considered relevant for the CCL Universe because it contains information on
air emissions, which may indicate potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://oaspub.epa. aov/eims/eimsapi.detail?deid=20797&partner=ORD-NCEA
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Derek
241
DEREK for Windows uses a knowledge base, which contains alerts describing structure-
toxicity relationships, with an emphasis on the understanding of mechanisms of toxicity and
metabolism.
Chemical structures can be easily inputted into DEREK for Windows via its automatic link to
ISIS/Draw or by importing MDL Molfiles or SDfiles. During an interactive session, DEREK
for Windows identifies the toxophore or substructure associated with toxicity and highlights
this to the user with a brief statement about the hazard it represents. At the touch of a button
the user can access additional information concerning the structure-toxicity relationship
including literature references and supporting examples.
The knowledge base covers a wide variety of important toxicological end points, which
include carcinogenicity, mutagenicity, skin sensitisation, teratogenicity, irritation, and
respiratory sensitisation.
It is now well known that the physicochemical properties of a compound play an important
role in determining potential toxicity. In recognition of this DEREK for Windows now
evaluates the predicted skin permeability of a chemical in order to predict its propensity to
induce skin sensitisation and photoallergenicity in humans. In the future, more of the
physicochemical properties of a chemical will be considered in order to predict its potential
toxicity over a wide range of end points more accurately, (description from website)
LHASA Limited
LHASA Limited
Department of Chemistry
University of Leeds
Leeds, LS2 9JT, UK
Tel:+44 (0)113 343 6531
Fax:+44 (0)113 343 6535
Sales: info@lhasalimited.org
Support: support@lhasalimited.org
or:
lhasa.harvard.edu
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, Description, References, Endpoint, Comments, LHASA Predictions: Genotoxicity,
Mutagenicity, Skin sensitisation
This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a
http://www.chem.leeds.ac.uk/luk/derek/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Derwent Crop Protection File (Derwent CROPU)
48
The CROPU File is a database that provides references to the worldwide journal literature on
all aspects of pesticides, including both biological and chemical information. Sources include
over 1,200 international journals, with coverage beginning in 1968 and conference
proceedings from 1985 to the present. They cover analysis, biochemistry, chemistry, and
toxicology of all pesticides, (description from website)
Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia
Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax: +1 2153862911
E-mail: sales@isinet.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.derwent.com/crop-protection/index.html
Data Source Name
Identification Number
Data Source Description
Derwent Crop Registry File (Derwent CROPR)
47
CROPR is a factual chemical registry database for chemicals in the Crop Protection File
(CROPU) database. Each reference lists the biological activity and chemical substructure
characteristics of an individual compound. The database supports structure-activity
searching (e.g., to generate a list of compounds with a specific structural feature that share
a common activity). Compounds selected in this database can then be searched in the
CROPU database for more extensive bibliographic information. The database draws on
scientific journals, conference proceedings, meeting reports, and basic patents. File data
Proprietor
Contact Information
include references on more than 8,000 pesticides from 1985 to the present, (description
from website)
Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia
Thomson Scientific
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax: +1 2153862911
E-mail: sales@isinet.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cas.orq/ONLINE/DBSS/croprss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Derwent Drug File (Derwent DRUGU)
49
The Derwent Drug File contains 1.5 million bibliographic references from the worldwide
pharmaceutical literature from 1964 to the present. The file also contains a structure-
searchable database which can be searched for specific compounds and their activities, and
provides bibliographic references. Subject coverage includes all aspects of drugs, such as
analysis, biochemistry, structure-activity relationships, pharmacokinetics, metabolism,
toxicology, and therapeutics. References are drawn from over 1,100 medical and scientific
journals and conference proceedings. The structure-searchable segment of the database
contains over 85,000 records, (description from website)
Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia
Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax: +1 2153862911
E-mail: sales@isinet.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.derwent.com/drugfile/index.html
Data Source Name
Identification Number
Data Source Description
Design Institute for Physical Property Data (DIPPR)
51
DIPPR contains "rigorously evaluated" data for pure component physical property data for
commercially important chemicals. Coverage includes 29 constant properties and 15
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
temperature dependent properties for 1,743 commercially important chemicals. DIPPR data
are compiled from published research data from 1982 to the present, (description from
website)
Supported by the American Institute of Chemical Engineers and maintained by Brigham
Young University
Van Yang
DIPPR® 801 Project Coordinator
350 CB, PO Box 24100
Provo, Utah 84602-4100
801 -422-9366 / fax: 801 -422-0517
dippr@byu.edu
Name, MW, Critical Temperature, Pressure, Volume, and Compressibility Factor, MP, Triple
Point Temperature and Pressure, Normal Boiling Point, Liquid Molar Volume, Enthalpy of
Formation (Ideal Gas and Standard State), Gibbs Energy of Formation (Ideal Gas and
Standard State), Entropy (Ideal Gas and Standard State), Enthalpy of Fusion, Standard Net
Heat of Combustion, Acentric Factor, Radius of Gyration, Solubility Parameter, Dipole
Moment, Van der Waals Volume and Area, Refractive Index, Flash Point, Upper and Lower
Flammability Limits, Autoignition Temperature, Liquid and Solid Density, Liquid and Solid
Vapor Pressure, Heat of Vaporization, Ideal Gas, Liquid, and Solid Heat Capacity, Second
Virial Coefficient, Vapor and Liquid Viscosity, Vapor, Liquid, and Solid Thermal Conductivity,
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://dippr.bvu.edu
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Developmental and Reproductive Toxicology/Environmental
Teratology Information Center (DART®/ETIC) Database
45
DART/ETIC is a bibliographic database on the National Library of Medicine's (NLM)
Toxicology Data Network (TOXNET®). It covers teratology and other aspects of
developmental and reproductive toxicology. It contains over 100,000 references to literature
published since 1965. DART/ETIC is funded by the U.S. Environmental Protection Agency,
the National Institute of Environmental Health Sciences, the National Center for
Toxicological Research of the Food and Drug Administration, and the NLM. (description from
website)
National Library of Medicine - Part of NLM TOXNET, funded by EPA, NIH, the FDA's
National Center for Toxicological Research, and NLM
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Telephone: (301)496-1131
FAX (301) 480-3537
e-mail: tehip@teh.nlm.nih.gov
URL: http://sis.nlm.nih.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7DARTETIC
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Dictionary of Substances and Their Effects - Knovel
50
This 2004 electronic version of the original seven-volume collection of vital information has
been updated to contain approximately 4,600 chemicals and their impact on the environment.
Detailed information about the toxicity of the chemicals, physical properties and regulatory
requirements is also presented. All information is presented with complete references
detailed at the end of each file. A live table is available, listing all chemicals and their
physical properties. The table contains hot links to an image of the chemical structure as well
as a link to the detailed information directly from the book. The detailed files can also be
accessed by browsing the table of contents. A newly added field allows records to be sorted
or filtered on the update date as this title will be continually updated. Chemicals can be
searched for by their chemical names as well as synonyms, molecular formulas, CAS
Registry and RTECS numbers. The data (text) files can be searched for keywords, and the
fields in the live table can be searched for physical properties, registry numbers, and
synonyms, (description from website)
Knovel
Knovel Corporation
13 Eaton Avenue
Norwich, NY 13815 USA
Tel: 1-607-337-5600
Fax: 1-607-334-9097
E-mail: info@knovel.com
Toxicity, Physical Properties, Regulatory Requirements, References
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.knovel.com/knovel2/default.isp
Data Source Name
Distributed Structure Searchable Toxicity Public Database Network
(DSSTox)
Identification Number
Data Source Description
Proprietor
Contact Information
53
Info from the following website: http://www.epa.gov/nheerl/dsstox/
The Distributed Structure-Searchable Toxicity (DSSTox) Database Network provides a
community forum for publishing standard format, structure-annotated chemical toxicity data
files for open public access. DSSTox databases are compilations and reformulations of
public databases that are made freely available on this website for any public use. The
DSSTox project has placed considerable emphasis, however, on implementing data and
documentation standards that are intended to encourage consistency in the use and reporting
of such data. This not only creates common public expectations and understanding of these
data, but also facilitates study reproducibility and greater community awarenessand
improvement of these data, (description from website)
EPA
DSSTox Technical Support
email: dsstox_support@epa.gov
Ann Richard
DSSTox Project Leader
email: richard.ann@epa.gov
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
919-541-3934
TD50
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://www.epa.aov/nheerl/dsstox/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Division of Bacterial and Mycotic Diseases (DBMD) - Disease
Information Listing
52
This database gathers in one place CDC's online resources concerning approximately 50
infectious bacterial diseases. For each infectious agent, a summary of the health
endpoints, transmission characteristics, and disease prevalence is given. At-risk groups and
current research are also summarized, and additional resources are listed for many
contaminants, (description from website)
CDC - Division of Bacterial and Mycotic Diseases
National Center for Infectious Diseases
Division of Bacterial and Mycotic Diseases
1600 Clifton Rd
MS
Atlanta GA 30333
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.aov/ncidod/dbmd/diseaseinfo/default.htm
Data Source Name
Identification Number
Data Source Description
EC Water Directive
242
Full text of directive:
http://europa.eu.int/smartapi/cgi/sga_doc?smartapi!celexplus!prod!CELEXnumdoc&lg=en&nu
mdoc=31998L0083
The old Drinking Water Directive of 1980 has provided the consumer security for drinking
water quality throughout the EU. However, it was both out of date as concerns
scientific/technical basis (original proposal was made in 1975) and the managerial approach.
Main thrust of the Commission Directive are:
Review of parametric values, and where necessary strenghtening them in accordance with
the latest available scientific knowledge (WHO Guidelines, Scientific Committee on
Toxicology and Ecotoxicology)
Increased transparency:
"Tapwater Directive" i.e. the point of use is the point of compliance with the quality standards
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Proprietor
Contact Information
Type of Data Elements
reference to ISO/CEN standards
obligation to report on quality
obligation to inform the consumer on drinking water quality and measures that they can take
to comply with the requirements of the Directive -in particular for lead- when the non-
compliance is because of the domestic distribution system (internal pipes, plumbing etc)
Streamlining legislation to parameters essential for health and environment: 66 parameters in
the old directive have been reduced to 48 (50 for bottled waters)in the new one, including 15
new parameters
Main changes in parametric values:
Lead: reduced from 50 ug/l to 10 ug/l, 15 years transition period to allow for replacing lead
distribution pipes
Pesticides:vaiues for individual substances and for total pesticides retained (0.1 ug/l /
0.5ug/l), plus additional, more stringent ones introduced for certain pesticides (0.03ug/l)
Copper: value reduced from 3 to 2 mg/l
Standards introduced for new parameters like trihalomethanes, trichloroethene and
tetracholoroethene, bromate, acrylamide etc.
This new Directive provides a sound basis for both the consumers throughout the EU and
the suppliers of drinking water.
Implementation deadlines:
The Directive entered into force on 25 December 1998.
Member States have 2 years i.e. until 25 December 2000 to transpose the Directive into
national legislation.
Member States have 5 years i.e. until 25 December 2003 to ensure that the Drinking water
complies with the standards set, except for Bromate (10 years), Lead (15 years) and
Trihalomethanes (10 years), (description from website)
European Community
European Commission
Environment DG
Information Centre
Office: BU-9 01/11
B -1049 Brussels
Belgium
Fax: +32 (0)2 299.61.98
Parameter, Parametric value, Unit, Notes, Trueness % of parametric value, Precision % of
parametric value, Limit of detection % of parametric value, Conditions
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains regulatory
limits for contaminants in drinking water.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://europa.eu.int/smartapi/cai/sga doc?smartapi!celexplus!prod!DocNumber&lg=en&tvpe
doc=Directive&an doc=1998&nu doc=83
Data Source Name
Identification Number
Data Source Description
Ecological Incident Information System
256
After a field has been treated with pesticides, wildlife may be exposed to these chemicals by
several routes. When the exposure is high relative to the toxicity of the pesticide, wildlife
may be killed or visibly incapacitated. Such events are called ecological incidents.
Many of these ecological incidents are probably not observed or reported, but when they are
reported to the proper authority (usually a state agency), they are investigated and an
incident report is generated.
In 1992, the Agency created a database called The Ecological Incident Information System
(ENS) to store information extracted from these incident reports.
The two primary sources of incident reports are pesticide registrants and government
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
agencies. Under section 6(a)(2) of the pesticide law FIFRA, pesticide registrants or
manufacturers are required to report to EPA any information related to known adverse
effects to the environment caused by their registered pesticides.
The second major source of information is investigative reports which are voluntarily
submitted to the Agency from state and other federal agencies that oversee agriculture,
wildlife, natural resources, and environmental quality. Diagnostic reports are also obtained
from the National Wildlife Health Institute (USGS), the Patuxent Wildlife Research Center
(USGS), the Southwest Wildlife Cooperative Disease Study, and state wildlife forensic
laboratories. Information is also extracted from accounts of ecological incidents reported in
newspapers and reliable internet sources.
The EMS was originally built in dBase III Plus, but was recently converted into a Lotus
Approach application. It is a relational database consisting of 89 distinct fields contained
within 13 related data tables.
Information in ENS records, if available, include the data and location of the incident, type
and magnitude of affects observed in various species, use(s) of pesticides known or
suspected of contributing to the incident, and the results of any chemical residue and
cholinesterase activity analyses conducted during the incident investigation.
Ecological incidents play an important role in the Agency's risk assessment and decision-
making process. Widespread ecological incidents for a pesticide may confirm a risk that was
predicted by risk assessment models, or it may indicate that the actual risk is greater or
less than that predicted by the model, (description from website)
EPA
Nicholas Mastrota at Mastrota.Nicholas@epa.gov or call 703-305-5247
Location of the Incident, Type and Magnitude of Affects, Use(s) of Pesticides, Results of
Chemical Residue and Cholinesterase Activity Analyses
This source does not meet relevance criteria because it contains only information on
ecological toxicity.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Retrievability Explanation
Source URL
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Ecology of Aquatic Hyphomycetes
56
Aquatic hyphomycetes were discovered 50 years ago by C.T. Ingold. They remained a
relatively obscure group until their role as intermediaries between deciduous leaves and
stream invertebrates was established some 20 years ago. This book, for the first time,
provides a comprehensive summary and critical evaluation of the biology and ecology of
these organisms. A special effort was made to evaluate the potential and actual insight that
have been or will be derived from work in related disciplines such as the ecology of other
fungal groups, stream ecology, or population ecology. The topics treated include the basic
life history of the fungi and the potential role of wood, a discussion of how the fungi have
adjusted to life in running water, their interactions with invertebrates, the attachment and
germination of their spores, what is known about sexual reproduction, how water chemistry
may influence their distribution and activity, how they react to human degradation of their
environment, and a summary of the research done on the Indian subcontinent. The volume
is of special interest to mycologists and stream ecologists and should facilitate the entry of
new workers into this exciting area. -This text refers to the Hardcover edition.
(description from Amazon.com)
Golley et al (eds.), Springer-Verlag: New York, 1992
Springer-Verlag New York
175 Fifth Avenue
New York, NY 10010
Phone:212-460-1500
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Fax:201-348-4505
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
Proprietor
ECOTOX - A Database of Toxic Effects to Aquatic and Terrestrial
Species
57
ECOTOX "represents an integration of AQUIRE, PHYTOTOX, and TERRETOX, which are
three existing EPA databases that contain ecotoxicity information for aquatic life, terrestrial
plants, and wildlife, respectively." ECOTOX also includes the Ecological Effects database of
toxicity data for aquatic and terrestrial species, provided by the EPA, Office of Pesticide
Programs (OPP), Ecological Effects Branch. Published papers on toxicology are reviewed,
and data are abstracted and reported in the appropriate database. Currently, ECOTOX
includes over 200,000 toxic effect listings from 16,899 references for more than 6,000
chemicals and 3,800 aquatic and terrestrial species, (description from website)
EPA Office of Research and Development - EPA, ORD, and NHEERL, Mid-Continent
Ecology Division
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
ECOTOX Support
Mid-Continent Ecology Division
6201 Congdon Boulevard
Duluth, MN 55804
Telephone: 218-529-5225
Fax:218-529-5003
E-mail: ecotox.support@epa.gov
Endpoint, Effect, Effect Measurement, Trend, Effect %, Media Type, Duration, Exposure
Type, Concentration (ug/L), Significance, Level, Response Site, BCF
This source does not meet relevance criteria because it contains only information on
ecological toxicity.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.epa.aov/ecotox/ecotox home.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Elsevier BIOBASE
63
Elsevier BIOBASE is a bibliographic database of current information on international
biological research. Subject coverage includes applied microbiology, cancer research,
clinical chemistry, ecological and environmental sciences, endocrinology and metabolism,
molecular biology, and toxicology. The database includes bibliographical and abstract
information from over 1,900 source journals, and contains records from 1994 to the present.
(description from website)
Elsevier Science Bibliographic Database, Amsterdam, the Netherlands
NORTH AMERICA
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
ebd-marketing@elsevier.com
Tel: +1 888 437 4636
Fax:+1 2126333975
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.elsevier.nl/homepage/sah/spd/site/
Data Source Name
Identification Number
Data Source Description
EMBASE
65
EMBASE is a bibliographic database of international literature on biomedical and
pharmaceutical fields. The database consists of abstracts and bibliographic information
from over 4,400 journals, and many books, conference proceedings, and reports, for a total
of over nine million citations and abstracts from 1974 to the present. Subject coverage
includes basic biological science (relevant to human medicine), biochemistry, clinical and
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
experimental medicine, drugs, environmental science, pharmacology, pollution control, public
health, and toxicology. EMBASE also provides access to drug literature, searchable by
chemical, trade, or manufacturer name, (description from website)
Elsevier Science Bibliographic Database, Amsterdam, the Netherlands
NORTH AMERICA
embase-usa@elsevier.com
Tel: +1 888 437 4636
Fax:+1 2126333975
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.elsevier.nl/homepage/sah/spd/site/
Data Source Name
Identification Number
Data Source Description
Endocrine Disrupter Priority Setting Database (EDPSD)
59
This database includes information queried from over 30 different databases specifically
relevant to health effects and exposure to potential endocrine disrupting chemicals, in readily
exportable tabular form. The data are organized into categories of exposure-related
information, effects-related information, combined exposure and effects-related information,
and specially targeted priorities (e.g., mixtures). More specifically, the database includes
many types of occurrence and health-effects information such as water and tissue
occurrence, and specific human-health endpoints, where available. Much of the data were
manipulated to provide summary statistics, weighting, or ranking prior to entry into the
database. Over 87,000 chemicals, including High Production Volume (HPV) Chemicals
(regulated under the Toxic Substances Control Act (TSCA)) and Pesticide Inert Chemicals,
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
are included, (description from website)
EPA Office of Prevention, Pesticides, and Toxic Substances; EPA, Office of Science
Coordination and Policy
John D. Walker
7401M
USEPA Headquarters
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Washington, DC 20460
202-564-7526
walker.johnd@epa.gov
Name, CASRN, HE and Occurrence data
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies and unique elements derived for measurements of
contaminants in water, providing an indicator of occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Retrievability Explanation
Source URL
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/scipolv/oscpendo/historv/finalrpt.htm
Data Source Name
Solutions
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Environmental Abstracts - LexisNexis Academic and Library
68
LexisNexis Environmental Abstracts allows user to search abstracts from thousands of
environmental journals, conference papers, and Federal government reports with links to
selected full text, (description from website)
LexisNexis
LexisNexis Academic & Library Solutions
4520 East-West Hwy
Bethesda MD 20814.3389 USA
Phone: 800.638.8380
Phone: 301.654.1550
Fax 301.657.3203
email: academicinfo@lexisnexis.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.lexisnexis.com/academic/1univ/envir/2ea.htm
Data Source Name
Identification Number
Data Source Description
Environmental Data Registry (EDR)
60
The EDR catalogs the EPA's major data collections and helps locate environmental
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Proprietor
Contact Information
information of interest. EDR does not store numerical data, but includes descriptive
metadata records for data kept elsewhere. The system integrates several collections of
EPA metadata, including data elements and chemical identification information. The
integrated information in EDR is accessed by the SRS and the CRS. (description from
website)
EPA
Michael Pendleton
United States Environmental Protection Agency
Office of Environmental Information
1200 Pennsylvania Avenue, NW
Mail Code 2822-T
Washington, DC 20460
email: pendleton.michael@epa.gov
Phone:(202)566-1658
Fax:(202)566-1639
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/edr/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Environmental Defense Fund (EOF) Chemical Profiles
58
Chemical profiles include information on over 11,000 chemicals, mostly those that are used
in large amounts or regulated under major environmental laws in the United States and/or
Canada. For the 650 chemicals in the TRI, the chemical profiles incorporate environmental
release, human health hazards, chemical use, regulatory coverage, basic hazard testing, and
safety assessment information to track the chemicals. The human health hazard data for
TRI chemicals is compiled from over 100 separate data sources on toxicology. Chemicals
not in TRI also have profiles, but with more limited data availability. Some ranking
information is available for a subset of the chemicals covered in the database, (description
from website)
Environmental Defense Fund (EOF)
National Headquarters
257 Park Avenue South
New York, NY 10010
Telephone: (212) 505-2100
Fax:(212)505-2375
Name, CASRN, recognized health hazards, suspected health hazards, general production
category;
This source is considered relevant for the CCL Universe because it contains information on
potential health effects.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.scorecard.org/chemical-profiles/
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Data Source Name
Identification Number
Data Source Description
Environmental Fate Databases
258
EPA's Office of Pesticide Programs (OPP) collects and reviews a variety of environmental
fate studies submitted by pesticide manufacturers in support of the registration of pesticide
products.
Environmental fate studies describe what happens to a pesticide in soil, water, and air after it
has been applied and include the following types of studies:
product chemistry,
metabolism,
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
hydrolysis,
photolysis,
field dissipation,
bioaccumulation,
adsorption/desorption and leaching.
After reviewing the data in these studies, OPP scientists summarize the information in Data
Evaluation Reports (DERs), Reregistration Eligibility Decision Documents (REDs), science
chapters, Emergency Use Exemptions, and other environmental fate reports.
In 2000, OPP initiated the development of a pesticide environmental fate database which will
allow the user to search and view the data, query the fate database, and print reports that
are found in these summary reports.
Presently, this database contains environmental fate and transport data for about 250
pesticide active ingredients. The Pesticide Program plans to complete the initial version of
this database by the end of 2002 and will be adding additional active ingredients during the
next two years, (description from website)
EPA
Larry Liu at Liu.Larry@epa.gov or call 703-305-5372
Environmental Fate Studies including, product chemistry, metabolism, hydrolysis,
photolysis, field dissipation, bioaccumulation, adsorption/desorption and leaching
This source is considered relevant for the CCL Universe because it contains environmental
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with BIOLOG, BIODEG, CHEMFATE, and DATLOG. EFDB simply
provides a link to, and leads to, BIOLOG, BIODEG, CHEMFATE, and DATALOG.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.aov/oppefed1/general/databasesdescription.htm - efd
Data Source Name
Identification Number
Data Source Description
Environmental Health Criteria (EHC) Monographs
61
Comprehensive data from scientific sources for the establishment of safety standards and
regulations
EHC publications are monographs designed for scientists and administrators responsible for
the establishment of safety standards and regulations. This series issued by the
International Programme on Chemical Safety (IPCS), provides basic scientific risk
evaluation of a wide range of chemicals and groups of chemicals.
EHC monographs are based on a comprehensive search of available original publications,
scientific literature and reviews and examine: the physical and chemical properties and
analytical methods; sources of environmental and industrial exposure and environmental
transport, chemobiokinetics and metabolism including absorption, distribution, transformation
and elimination; short and long term effects on animals (carcinogenicity, mutagenicity, and
teratogenicity); and finally, an evaluation of risks for human health and the effects on the
environment, (description from website)
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Proprietor
Contact Information
International Programme for Chemical Safety, World Health Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, Synonyms, formula, structure, CASRN, ID numbers, MW, BP, MP, FP, density,
flash point, flammable limits, vapor density, VP, water solubility, other solubility, odor
threshold, taste threshold, Log Kow, Log Koc, GV, CCx, CVx, ECx, LCx, LDx, LO(A)EL,
This source is considered relevant for the CCL Universe because it contains data elements
(LDx, LO(A)EL, NO(A)EL) from toxicological studies.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of INTOX (source 105).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/ehc.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Environmental Information Management System (EIMS)
62
The EIMS system "stores, manages, and delivers descriptive information for data sets,
databases, documents, models, multimedia, projects, and spatial environmental information".
The system "stores and maintains descriptive information in a relational database and
refers to the products (i.e., data, documents, etc.) stored either within EIMS or as distributed
external files", (description from website)
EPA, ORD
ORD Helpdesk:
Phone: 919-380-4588
Fax: 919-466-0055
ord.omishelpdesk@epa.gov
Analytical Method, Concentration, # Samples Contaminated, Sensitivity of Sampling Design,
State, Basin, Primary Water Use, Project Period, Month, Week
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.qov/eims/eims.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Monitoring and Assessment Program (EMAP)
64
EMAP is a database of geographical and water quality data for agro-ecosystems, the Great
Lakes, estuaries, landscape ecology, surface waters, and wetlands. Analytical data are
currently available for estuaries and some surface waters only. Data on water chemistry,
soil chemistry, pesticide use, and other data for specific locations are included, (description
from website)
EPA
Environmental Monitoring and Assessment Program
Melissa Hughes
US EPA
Atlantic Ecology Division
27 Tarzwell Drive
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Narragansett, Rl 02882
email: hale.stephen@epa.gov
email: emap@epa.gov
Phone: 401 7823184
Fax: 401 782 3030
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Assemblage Counts, Chlorophyll Data, Assemblage Metrics, Counts Data, Diatom Data,
This source is considered relevant because it contains geographical and water quality data,
providing an indicator of potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.qov/emap/html/datal/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Environmental Monitoring Methods Index (EMMl)
67
The EPA's Environmental Monitoring Methods Index (EMMI) is its official analytical methods
database, containing methods for over 3,800 water contaminants. EMMI allows the user to
access an extensive list of analytes and analytical methods. The database contains method
abstracts that include sample collection, storage, preservation, preparation, extraction, and
analysis information, (description from website)
EPA
U.S. Environmental Protection Agency
Office of Water (4101M)
1200 Pennsylvania Avenue, N.W.
Washington, D.C. 20460
email: OW-GENERAL@epa.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://vosemite.epa.aov/water/owrccatalog.nsf/
Data Source Name
Identification Number
Environmental Mutagen Information Center Database (EMIC)
66
Data Source Description
Proprietor
Contact Information
EMIC is a bibliographic database on the NLM TOXNET® system. It covers chemical,
biological, and physical agents that have been tested for genotoxic activity. It contains
some 20,000 literature citations published since 1991. (description from website)
National Library of Medicine; prepared by EMIC/Oak Ridge National Laboratory
(EMIC/ORNL), Oak Ridge, Tennessee, for the Federal government
Specialized Information Services
NLM/NIH
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
2 Democracy Plaza, Suite 510
6707 Democracy Blvd., MSC 5467
Bethesda, MD 20892-5467
Phone: 301-496-1131 (local and international)
Fax: 1-301-480-3537
Toll Free: 1-888-FINDNLM
E-mail: tehip@teh.nlm.nih.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlqen7EMIC
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Environmental Pollution - Elsevier Science
69
Environmental Pollution is an international journal that addresses issues relevant to the
nature, distribution and ecological effects of all types and forms of chemical pollutants in
air, soil and water. The Editors welcome articles based on original research, findings from
re-examination and interpretation of existing data and reviews of important issues. In
addition, the journal also publishes articles on new methods of detection, study and
remediation of environmental pollutants.
All types of pollution are covered, including atmospheric pollutants, detergents, fertilizers,
industrial effluents, metals, mining wastes, oil, pesticides, plastics, radioactive materials and
sewage, (description from database)
Elsevier
Customer Service Department
6277 Sea Harbor Drive
Orlando, FL 32887-4800 USA
Email: usjcs@elsevier.com
US Customers:
Toll Free:+1 (877)839-7126
Fax:+1 (407)363-1354
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.elsevier.nI/inca/publications/store/4/0/5/8/5/6/
Data Source Name
Identification Number
Data Source Description
Environmental Science and Technology
70
ES&T is a unique source of information for scientific and technical professionals in a wide
range of environmental disciplines. In its research section, contributed material may appear
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
as current research papers, policy analyses, or critical reviews. Also included is a magazine
section called the A-Pages that provides authoritative news and analysis of the major
developments, events, and challenges shaping the field, (description from website)
American Chemical Society
American Chemical Society
1155 16th St., N.W.
Washington, DC 20036
Phone: (202) 872-4582
Fax: (202) 872-4403
E-mail: est@acs.org
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://pubs.acs.org/iournals/esthaa/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Sciences and Pollution Management - Cambridge
Scientific Abstracts
71
This multidisciplinary database, provides unparalleled and comprehensive coverage of the
environmental sciences. Abstracts and citations are drawn from over 5980 serials including
scientific journals, conference proceedings, reports, monographs, books and government
publications. Major areas of coverage include: Agricultural biotechnology, Air quality, Aquatic
pollution, Bacteriology, Ecology, Energy resources, Environmental biotechnology,
Environmental engineering, Environmental impact statements (U.S.), Hazardous waste,
Industrial hygiene, Microbiology related to industrial & environmental issues, Pollution: land,
air, water, noise, solid waste, radioactive, Risk assessment, Safety science, Toxicology &
toxic emissions, Water pollution, Waste management, Water resource issues, (description
from website)
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Email: sales@csa.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.csa.com/csa/ids/databases-collections.shtml - environmental
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
European Inventory of Existing Commercial Substances (EINECS)
Information System
55
The online EINECS Information System allows you, through the European Inventory of
Existing Commercial Substances (EINECS), to find General information concerning a
chemical substance like CAS number, EINECS number, Substance Name and Chemical
Formula. The current EINECS contains 100 196 chemical substances.
(description from website)
European Chemicals Bureau (ECB)
sharon.munn@jrc.it
remi.allanou@jrc.it
Name, CASRN, EINECS ID, LDx, NOAEL (not available for all contams)
This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ecb.irc.it/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Eurosurveillance
72
EuroSurveillance publishes: weekly and monthly reports on infectious disease outbreaks in
member countries; epidemiological updates; and analysis of disease trends in Europe.
(description from website)
Eurosurveillance; European Commission (EC)
Eurosurveillance Weekly
Health Protection Agency
Communicable Disease Surveillance Centre
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
61 Colindale Avenue
London NW9 5EQ
eurosurveillance.weekly@hpa.org.uk
Tel. 44 (0)20-8200 6868
extension 4417
Fax: 020 8200 7868
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.eurosurveillance.org/index-02.asp
Data Source Name
Identification Number
Data Source Description
Everything Added to Food in the United States (EAFUS) Database
54
This is an informational database maintained by the U.S. Food and Drug Administration
(FDA) Center for Food Safety and Applied Nutrition (CFSAN) under an ongoing program
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
known as the Priority-based Assessment of Food Additives (PAFA). It contains
administrative, chemical and toxicological information on over 2000 substances directly
added to food, including substances regulated by the U.S. Food and Drug Administration
(FDA) as direct, "secondary" direct, and color additives, and Generally Recognized As Safe
(GRAS) and prior-sanctioned substances. In addition, the database contains only
administrative and chemical information on less than 1000 such substances. The more than
3000 total substances together comprise an inventory often referred to as "Everything"
Added to Food in the United States (EAFUS).
This list of substances contains ingredients added directly to food that FDA has either
approved as food additives or listed or affirmed as GRAS. Nevertheless, it contains only a
partial list of all food ingredients that may in fact be lawfully added to food, because under
federal law some ingredients may be added to food under a GRAS determination made
independently from the FDA. The list contains many, but not all, of the substances subject
to independent GRAS determinations, (description from website)
FDA - Center for Food Safety and Applied Nutrition; CFSAN, Office of Food Additive
Safety
CFSAN Outreach and Information Center
Center for Food Safety and Applied Nutrition
5100 Paint Branch Parkway (HFS-555)
College Park, MD 20740
Toll-Free Information Line:
1-888-SAFEFOOD (1-888-723-3366)
Name, CASRN, status of toxicology information
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://vm.cfsan.fda.gov/~dms/eafus.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Extension TOXicology NETwork (EXTOXNET)
73
Several databases are maintained under EXTOXNET that include various types of pesticide
toxicology and environmental chemistry information, such as discussions of Toxicological
Issues of Concern (TICs); toxicology newsletters; other resources for toxicology
information; toxicology fact sheets; Pesticide Information Profiles (PIPs); and Toxicology
Information Briefs (TIBs). TIBs are informational briefs that are designed to help the public
understand principles of toxicology. PIPs are documents that provide specific pesticide
information relating to health and environmental effects, but are not based on an exhaustive
literature search, so they may not be complete in their coverage or data reporting.
Information includes toxicological effects, regulatory status, chemical properties,
formulations, synonyms/trade names, chemical class, ecological effects, environmental
fate, degradation, and major manufacturers, presented in a profile format. More than 180
pesticides are included in the database, (description from website)
Produced and maintained through the cooperative effort of the University of California-
Davis, Oregon State University, Michigan State University, Cornell University, and the
Terry L. Miller
extoxnet@ace.orst.edu
Name, CASRN, trade names, regulatory status, LD50, critical effect, chronic toxicity,
reproductive, teratogenic, mutagenic, cancinogenic, organ toxicity, ecotoxicity, half life in
soil and water, water solubility, MW, other solubility, MP, VP, partition coefficient, adsorption
coefficient, ADI, MCL, RfD, PEL, HA, TLV
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It does not meet considerations because there was no documentation on how the data were
obtained.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ace.ace.orst.edu/info/extoxnet/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Facilities Index Data System
274
FINDS contains entries for sites and facilities regulated by the US EPA under a variety of
statutes. Some of these include RCRA, CERCLA, the Clean Air Act, the Clean Water Act,
TSCA, FIFRA, TRIS, and more.
SUBJECT COVERAGE:
Geographic location and identification data
Classification codes for the site
Listing of EPA and state databases containing more information about the site
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Geographic location and identification data,
Classification codes for the site, Listing of EPA and state databases containing more
information about the site
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/finds.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) List
289
The primary focus of FIFRA was to provide federal control of pesticide distribution, sale,
and use. EPA was given authority under FIFRA not only to study the consequences of
pesticide usage but also to require users (farmers, utility companies, and others) to register
when purchasing pesticides.
All pesticides used in the U.S. must be registered (licensed) by EPA. Registration assures
that pesticides will be properly labeled and that if in accordance with specifications, will not
cause unreasonable harm to the environment.
EPA
Unknown
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is accessible through EPA's Substance
Registry System.
Data Source Name
Identification Number
Data Source Description
Proprietor
Food Commodity Intake Database
263
The Food Commodity Intake Database (FCID) was developed as a cooperative effort by the
United States Department of Agriculture (USDA) and OPP for use by EPA and other
organizations when conducting the exposure components of dietary risk assessments. The
FCID includes data from two surveys conducted by USDA: Continuing Survey of Food
Intakes by Individuals, and a Supplemental Children's Survey. These surveys provide
useful information on 5,831 different foods and beverages people of different ages reported
eating in 1994-96 and 1998. (FCID) is available on CD-ROM from the National Technical
Information Service (NTIS). The product order number is PB2000-500101. (description from
website)
US DA/EPA
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Technical Information Service
5285 Port Royal Road, Springfield, VA 22161
webmaster@ntis.gov
Unknown
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It does not meet considerations because no information on type of data elements is
available.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www. ntis.gov/search/results. asp?loc=3-0-0
Data Source Name
List
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Food Quality Protection Act (FQPA) - "Cumulative to Pesticides"
75
The Food Quality Protection Act requires that the Environmental Protection Agency take into
account cumulative exposure to pesticides from all sources. In accordance with this, the
EPA is in the process of reassessing tolerances for a number of pesticides. This process will
take a number of years to complete. The first pesticides to be assessed will be the
organophosphates, carbamates, and pesticides thought to be cancer-causing agents (B1 and
B2 carcinogens). This database allows you to search by a widely-used pesticide trade name
and receive the name of the active ingredient. You can also do the reverse: enter an active
ingredient name and receive a list of common trade names. The database contains pesticide
active ingredients that are of special interest in the FQPA process.
(description from website)
EPA OPP, Cornell Pesticide Management Education Program
PMEP Staff
5123 Comstock Hall
Cornell University
Ithaca, New York 14853-0901
(607J-255-1866
Name
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with the list of contaminants in FIFRA.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://pmep.cce.cornell.edu/fapa/fgpa-list.html
Data Source Name
Identification Number
Data Source Description
Food Net
74
FoodNet performs active surveillance for laboratory-confirmed cases of seven bacterial and
two parasitic organisms in limited parts of the country representing 10 percent of the U.S.
population for: Campylobacter, Salmonella, E. coli O157: H7, Listeria monocytogenes,
Shigella, Vibrio parahaemolyticus, Yersinia enterocolitica.Cyclospora cayetanensis, and
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Retrievability Explanation
Source URL
Cryptosporidium parvum. For each organism, general information, technical information,
and FoodNet Publications are presented. General information includes health effects, routes
of exposure, medical treatment, and regulations. Technical information includes
epidemiological trends. "In active surveillance, the laboratories in the catchment areas are
contacted regularly by collaborating FoodNet investigators to collect information on all of the
laboratory-confirmed cases of diarrheal illness." (description from website)
Produced and maintained by a collaboration of the CDC, nine Emerging Infection Program
(EIP) sites, USDA, and FDA
National Center for Infectious Diseases
Division of Bacterial and Mycotic Diseases
1600 Clifton Rd
MS
Atlanta GA 30333
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.qov/foodnet/pus.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Gastrointestinal Absorption Database
277
GIABS contains bibliographic citations to studies of absorption, distribution, metabolism, or
excretion of chemical substances by human or animal test subjects. Each record deals with
a specific experiment on a specific chemical as abstracted from a specific article.
SUBJECT COVERAGE:
Bibliographic references
CAS Registry Numbers
Chemical name identification
Duration of test
Experimental conditions
Route of application
Species and strain of subject
(description from website)
National Information Services Corporation (NISC)/EPA
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Contact Information
Type of Data Elements
Relevance Explanation
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.nisc.com/cis/details/giabs.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
GenBank® - National Center for Biotechnology Information
77
"GenBank® is a genetic sequence database, containing an annotated collection of all publicly
available deoxyribonucleic acid (DNA) sequences. The current collection includes
approximately 17,089,000,000 bases in 15,465,000 sequences, as of February 2002." The
coverage of the sequence records includes 5 complete bacteria, 50 retroviruses, and 39
plasmids. (description from website)
Carnegie Mellon University; GenBank® is produced and maintained by the NCBI at NIH
National Center for Biotechnology Information
National Library of Medicine
Building 38A
Bethesda, MD 20894
Voice: (301)496-2475
Fax: (301)480-9241
Locus, Definition, Accession, Version, Keywords, Source, Organism, Reference, Authors,
Title, Journal, Features, Source, Gene, CDS, Variation, Genetic Sequence
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.ncbi.nlm.nih.aov/Genbank/GenbankOverview.html
Data Source Name
Identification Number
Data Source Description
Generally Regarded As Safe (GRAS) Substance List
81
The summary tables provide the following information about GRAS notices received within
each year since 1998, when FDA received its first GRAS notice:
The name of the substance
The file number (CRN No.) that FDA has assigned to the notice
A hyperlink to the letter that FDA sent in response to the notice
Within the summary table for each year, there is a hyperlink to a table that provides more
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details about the GRAS notices received in that year. This includes:
The name of the notifier
The intended conditions of use
Within the detailed table for each year, there is a hyperlink to the address of the notifier.
These tables are current as of April, 2004, and therefore, does not show any new notices
filed by FDA, or response letters issued by FDA, after that date. This table will be updated
approximately monthly, (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
FDA - Center for Food Safety and Applied Nutrition
Office of Food Additive Safety (HFS-200)
Center for Food Safety and Applied Nutrition
Food And Drug Administration
5100 Paint Branch Parkway
Notifier, Intended Use, Basis, Receipt Date, Closure Date
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://www.cfsan.fda.aov/~rdb/opa-gras.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Genetic Activity Profiles (GAP) Database
76
The GAP database synthesizes around 8,000 short-term test result references on genetic
toxicity. Coverage includes approximately 500 chemicals evaluated by International Agency
for Research in Cancer (IARC) Working Groups and published in IARC Monographs, and
over 250 EPA priority chemicals, including pesticides. Data records in GAP include "the
chemical name and CAS registry number, a test code, test endpoint, test results, highest
ineffective dose (HID) or lowest effective dose (LED), reference number, and a reference
citation".
EPA/IARC
No longer available
Chemical name, CAS registry number, test code, test endpoint, test results, highest
ineffective dose (HID) or lowest effective dose (LED), reference number, reference citation
This source is considered relevant for the CCL Universe because it contains information on
mutagenicity, which may be an indicator of potential health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source has been withdrawn; it is no longer available online.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
GENE-TOX
78
GENE-TOX is a toxicology data file of the National Library of Medicine's (NLM) Toxicology
Data Network (TOXNET®). It is created by the U.S. Environmental Protection Agency (EPA)
and contains genetic toxicology (mutagenicity) test data, resulting from expert peer review
of the open scientific literature, on over 3000 chemicals. The GENE-TOX program was
established to select assay systems for evaluation, review data in the scientific literature,
and recommend proper testing protocols and evaluation procedures for these systems.
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
(description from website)
National Library of Medicine; Created by EPA; maintained by NIH's NLM
GENE-TOX Representative
National Library of Medicine
Specialized Information Services
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301)496-1131
e-mail: toxmail@toxnetmail.nlm.nih.gov
URL: http://sis.nlm.nih.gov
Name, CASRN, Mutagenicity Studies, Assay Type, Evaluation Results, Panel Report,
Reference, Species/Cell Type, Species/Cell Type Sex, Taxonomic Name & Assay
This source is considered relevant for the CCL Universe because it contains information on
mutagenicity, which may be an indicator of potential health effects.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7GENETOX
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Genomes and Databases
79
This web site catalogs bioscience databases available on the Internet, particularly genome
databases. Multi-organism and organism-specific databases are listed. Specific organisms
with genome data available are typical research organisms, such as mouse, Drosophila, E.
coli, and C. elegans. (description from website)
Highveld.com, a commercial guide for scientists (industry-sponsored).
Unknown
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.hiahveld.com/genome.html
Data Source Name
Identification Number
Global Infectious Disease and Epidemiology Network (GIDEON)
80
Data Source Description
Proprietor
Contact Information
GIDEON is an electronic diagnostic tool that incorporates epidemiological, diagnostic, and
treatment data for 936 microbial pathogens. It can be searched by symptoms or by
microbial characteristics. Pathogen occurrence is recorded by country to facilitate
diagnosis.
GIDEON Informatics; CY Informatics
GIDEON Informatics, Inc
6010 Wilshire Blvd, Suite 302
Los Angeles, CA 90036
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Toll free: (866) 699-3159
Phone: +1 (604) 699-3058
E-MAIL: info@gideononline.com
FAX: +1 (309)424-1801
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.cvinfo.com/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Ground Water On-Line - National Ground Water Association
82
Ground Water On-Line® is a database containing 90,331 ground water literature citations with
key words, abstracts, chemical compounds, biological factors, geographic locations, authors,
titles, publication source names, and more. Each citation may contain up to 25 fields of
information.
Documents that are indexed include scientific, technical, and trade journals; newsletters;
books; government documents; university reports; dissertations and theses; state
publications; and proceedings of national and international conferences and symposia. The
collection is the largest and most comprehensive of its kind in the world, (description from
website)
National Ground Water Association
601 Dempsey Road
Westerville, OH 43081-8978
Phone/Toll-free 800 551.7379/ 614 898.7791
Fax/614898.7786
E-mail/ngwa@ngwa.org
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nawa.ora/awonline/gwol.html
Data Source Name
Identification Number
Data Source Description
Guidelines for Canadian Drinking Water Quality (CADW): Summary
of Guidelines
83
The Summary of Guidelines for Canadian Drinking Water Quality provides guidelines
(Maximum acceptable concentration (MAC), Interim maximum acceptable concentration
(IMAC), Aesthetic objectives (AO) for approximately 197 microbiological, physical/chemical
and radiological parameters that are associated with drinking water and are known, or
suspected to be harmful.
Health Canada has published Guidelines for Canadian Drinking Water Quality since 1968.
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The guidelines are prepared by the Federal-Provincial-Territorial Committee on Drinking
Water. This Committee is composed of representatives from each province and territory,
as well as from Health Canada. The "Summary of Guidelines for Canadian Drinking Water
Quality" is updated and published every spring on Health Canada's website (www.hc-
sc.gc.ca/waterquality). The most recent update was published in April 2003.
The guidelines contain authoritative information on exposure, health effects, analytical
methods, and treatment for drinking water contaminants. Coverage of the documents
includes microbiological, chemical (both organic and inorganic), physical, and radiological
issues. Each contaminant or issue is covered in a separate guideline document, which
addresses the derivation of Maximum Allowable Concentrations (MACs) for each substance
or water quality parameter. The website states that: "These reviews are not exhaustive, but
present a brief summary of background data and information considered to be critical for the
derivation of the guidelines." Guidelines exist fora total of over 80 water quality
parameters at this time, with more in preparation, (description from website)
Health Canada
Water Quality and Health Bureau
2720 Riverside Drive, AL 6604B
Ottawa, Ontario, K1AOK9
Fax: (613)952-2574
Email: water_eau@hc-sc.gc.ca
ADI, AO, CR, Critical Effect, DCF, Dose, Duration, Environmental Fate, Guideline,
Half-life t1/2 (days), IMAC (mg/L), LDx, MAC, NO(A)EL, Occurrence, Physical/Chemical,
Production/Use, Route
This source is considered relevant for the CCL Universe because it contains data elements
(ADI, NO(A)EL) from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.hc-sc.gc.ca/hecs-sesc/water/pdf/summarv.pdf
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Guidelines for Canadian Drinking Water Quality (CADW):
Supporting Documentation
84
The guidelines contain authoritative information on exposure, health effects, analytical
methods, and treatment for drinking water contaminants. Coverage of the documents
includes microbiological, chemical (both organic and inorganic), physical, and radiological
issues. Each contaminant or issue is covered in a separate guideline document, which
addresses the derivation of Maximum Allowable Concentrations (MACs) for each substance
or water quality parameter. The website states that: "These reviews are not exhaustive, but
present a brief summary of background data and information considered to be critical for the
derivation of the guidelines." Guidelines exist for a total of over 80 water quality
parameters at this time, with more in preparation, (description from website)
Health Canada
Water Quality and Health Bureau
2720 Riverside Drive, AL 6604B
Ottawa, Ontario, K1AOK9
Fax:(613)952-2574
Email: water_eau@hc-sc.gc.ca
Name, synonyms, formula, iMAC, MAC, IARC cancer class, ADI, MTD, LDx, NO(A)EL,
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.hc-sc.ac.ca/hecs-sesc/water/dwgsup.htm
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Hazardous Substances Data Bank (HSDB)
95
HSDB is a toxicology data file on the National Library of Medicine's (NLM) Toxicology Data
Network (TOXNET®). It focuses on the toxicology of potentially hazardous chemicals. It is
enhanced with information on human exposure, industrial hygiene, emergency handling
procedures, environmental fate, regulatory requirements, and related areas. All data are
referenced and derived from a core set of books, government documents, technical reports
and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review
Panel (SRP), a committee of experts in the major subject areas within the data bank's scope.
HSDB is organized into individual chemical records, and contains over 4500 such records.
(description from website)
National Library of Medicine, NIH
HSDB Representative
National Library of Medicine
Specialized Information Services
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301)496-1131
e-mail: tehip@teh.nlm.nih.gov
Name, CASRN, synonyms, ID numbers, Use, Production, IARC cancer class, EPA cancer
group, Evidence for carcinogenicity, Critical effect, Mutagenicity, Irritation data, Susceptible
populations, Body burden, Occupational exposure, MTD, LDx, Estimated daily intake, Study
data (most without specific NOAEL/LOAEL), NTP studies, Ecotox, TSCA test submissions,
HA levels, Regulatory requirements, Federal and State DW regulations, State DW
guidelines, Molecular formula, MW, Color/form, Odor, Taste threshold, BP, MP, Critical
temperature and pressure, Density, Specific gravity, Heat of combustion, Heat of
vaporization, Log Kow, Solubilities, Spectral properties, Surface tension, Vapor density, VP,
Relative evaporation rate, Viscosity, Blood/air partition coefficient, Heat of fusion, Heat
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
Redundancy Explanation
Retriev'ability Explanation
Source URL
capacity, HLC This source is not redundant.
The list of contaminants in HSDB is retrievable. The data are not formatted for automated
retrieval. The HSDB is a unique and exceptional source and is included to supplement the
CCL Universe.
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7HSDB
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Health Advisories (HA) Summary Tables - EPA
87
Drinking Water and Health Advisory summary tables are prepared periodically by the U.S.
Environmental Protection Agency, Office of Water, Office of Science and Technology. They
contain drinking water standards in the form of non-enforceable concentrations of drinking
water contaminants, Maximum Contaminant Level Goals (MCLGs), or enforceable Maximum
Contaminant Levels (MCLs). Maximum Contaminant Levels are the maximum permissible
level of a contaminant in water delivered to users of a public water system. Health
Advisories (HA's) provide information on contaminants that can cause human health effects
and are known or anticipated to occur in drinking water. Health Advisories are guidance
values based on non-cancer health effects for different durations of exposure (e.g., one-
day, ten-day, and lifetime). They provide technical guidance to EPA Regional Offices, State
governments, and other public health officials on health effects, analytical methodologies,
and treatment technologies associated with drinking water contamination (taken directly from
website). The Health Advisories Summary Tables provide drinking water standards for
approximately 227 contaminants, (description from website)
EPA Office of Water; OST
SAFE DRINKING WATER HOTLINE
1-800-426-4791 or 703-285-1093
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Copies of the supporting technical documentation for the health advisories can be ordered
for a fee from:
Educational Resource Information Center (ERIC)
1929 Kenny Road
Columbus, OH 43210-1080
Telephone number 614-292-6717; 1-800-276-0462
FAX 614-292-0263
e-mail ERICSE@osu.edu
Name, CASRN, CR, DWA, DWEL, HA (1d, 10d, lifetime), MCL, MCLG, RfD, SDWR
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/ost/drinking/standards/dwstandards.pdf
Data Source Name
Identification Number
Data Source Description
Health Advisory Documents
The U.S. Environmental Protection Agency (EPA) has prepared Health Effects
Support Documents to assist in determining whether to establish a National Primary Drinking
Water Regulation (NPDWR) for 9 CCL contaminants. Health Advisory documents provide
information on contaminants that can cause human health effects and are known or
anticipated to occur in drinking water.
The above link accesses an example of what a Health Advisory document consists of.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
EPA Office of Water
SAFE DRINKING WATER HOTLINE
1-800-426-4791 or 703-285-1093
Copies of the supporting technical documentation for the health advisories can be ordered
for a fee from:
Educational Resource Information Center (ERIC)
1929 Kenny Road
Columbus, OH 43210-1080
Telephone number 614-292-6717; 1-800-276-0462
FAX 614-292-0263
e-mail ERICSE@osu.edu
Dose response assessments, Exposure from drinking water, Exposure from environmental
media other than water, Hazard identification, Physical and chemical properties, Regulatory
determination and characterization of risk, Toxicokinetics, Uses and environmental fate from
drinking water
This source is considered relevant for the CCL Universe because it contains data elements
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/safewater/ccl/pdf/hedoc-aldrin dieldrin-final.pdf
Data Source Name
Identification Number
Data Source Description
Health and Safety Guides - World Health Organization, ILO, UNEP,
CCOHS
89
Health and Safety Guides (HSG) provide concise information in non-technical language, for
decision-makers on risks from exposure to chemicals, with practical advice on medical and
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
administrative issues.
The Health and Safety Guide series are published by the World Health Organization for the
International Programme on Chemical Safety (a collaborative programme of the United
Nations Environment Programme, the International Labour Organisation and the World Health
Organization) and hard copies can be obtained from the Office of Distribution and Sales,
World Health Organization,1211 Geneva 27, Switzerland, (description from website)
World Health Organization, International Labour Organisation, United Nations Environment
Programme, Canadian Centre for Occupational Health and Safety
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
CASRN, Physical/Chemical, Environmental Fate, Production/Use, Occurrence, Ecological
Toxicity, Species, Route, Dose, Frequency, Duration, Critical Effect, CLV, ERL, MAC,
MR(es)L, MXL, RECL, STEL, TWA, LCx, LDx, LO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Source URL
http://www.inchem.org/paaes/hsa.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Health Effects Assessment Summary Tables (HEAST) - EPA NCEA
91
The Annual Health Effects Summary Tables (HEAST) are for use at both Superfund and
RCRA sites. It is maintained by the Environmental Protection Agencys National Center for
Environmental Assessment and provides a comprehensive listing of provisional risk
assessment information relative to oral and inhalation routes of exposure for chemicals. In
this document, slope factors are calculated by EPA to assist HEAST users with risk-related
evaluations and decision-making at various stages of the remediation process.
EPA NCEA
Dave Crawford
by phone at: 703-603-8891
or by email at: crawford.dave@epa.gov
Name, CASRN, Slope factor, Unit risk, RfD, RfC
This source is considered relevant for the CCL Universe because it contains data elements
(RfDs) from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
Healthlnsite
90
Healthlnsite is an Australian Government initiative, funded by the Department of Health and
Ageing. It aims to provide easy access to quality information about human health. Content
is provided through information partnerships established between Healthlnsite and selected
organisations providing quality information on their websites. Organisations and websites
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
whose content has been proposed for access through Healthlnsite must go through the
process for the assessment of content for Healthlnsite and be approved by a highly
qualified editorial board. Through Healthlnsite you can find a wide range of up-to-date and
quality assessed information on important health topics such as diabetes, cancer, mental
health and asthma, (description from website)
Government of Australia
Healthlnsite Editorial Team
Online Communications Section
Department of Health and Ageing, MDP 62
GPO Box 9848
Canberra ACT 2601
Telephone: 02 6289-8488
Fax: 02 6289-3671
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.healthinsite.gov.au/index.cfm
Data Source Name
Identification Number
Data Source Description
High Production Volume (HPV) Challenge Program Robust
Summaries and Test Plans
94
The U.S. high production volume (HPV) chemicals are those which are manufactured in or
imported into the United States in amounts equal to or greater than one million pounds per
year. The U.S. HPV chemicals were identified through information collected under the Toxic
Substances Control Act (TSCA) Inventory Update Rule (IUR). Organic chemicals that are
manufactured in, or imported into, the United States in amounts equal to or exceeding 10,000
pounds per year are subject to reporting under the TSCA IUR. Reporting is required every
four years.
The HPV Challenge Program Chemical List consists of all the HPV chemicals reported during
the 1990 IUR reporting year. Inorganic chemicals and polymers, except in special
circumstances, were not subject to the IUR reporting requirements, although a number were
reported in error. The HPV Challenge Program Chemical List contains about 2,800 chemicals.
Proprietor
Contact Information
Type of Data Elements
The 1990 IUR list was selected as the starting point for this program. As subsequent
reporting years identify additional chemicals (including inorganics, once the corresponding
reporting requirements have been added under the IUR), they will be posted here for
information purposes. EPA expects that, over time, the testing of new HPV chemicals will
become routine, and companies may wish to test new HPV chemicals as they appear.
(description from website)
EPA
Administrator
US Environmental Protection Agency
P.O. Box1473
Merrifield, VA22116
Attention: Chemical Right-to-Know Program
By Phone: (202) 564-4770
Name, CASRN, Structure, Acute Toxicity (LD50), Repeated Dose Toxicity (NOAEL, LOAEL),
Genetic Toxicity in vitro, Genetic Toxicity in vivo, Reproductive Toxicity, Developmental
Toxicity, Acute Ecotoxicity (fish and aquatic invertebrates), Photodegradation, Stability in
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Water (hydrolysis), Transport and Distribution (fugacity), Biodegradation (half-life), MP, BP,
VP, Log Kow, Water Solubility
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.qov/chemrtk/viewsrch.htm
Data Source Name
High Production Volume (HPV) Chemical List
Identification Number
Data Source Description
93
The U.S. high production volume (HPV) chemicals are those which are manufactured in or
imported into the United States in amounts equal to or greater than one million pounds per
year. The U.S. HPV chemicals were identified through information collected under the Toxic
Substances Control Act (TSCA) Inventory Update Rule (IUR). Organic chemicals that are
manufactured in, or imported into, the United States in amounts equal to or exceeding 10,000
pounds per year are subject to reporting under the TSCA IUR. Reporting is required every
four years.
The HPV Challenge Program Chemical List consists of all the HPV chemicals reported during
the 1990 IUR reporting year. Inorganic chemicals and polymers, except in special
circumstances, were not subject to the IUR reporting requirements, although a number were
reported in error. The HPV Challenge Program Chemical List contains about 2,800 chemicals.
The 1990 IUR list was selected as the starting point for this program. As subsequent
reporting years identify additional chemicals (including inorganics, once the corresponding
reporting requirements have been added under the IUR), they will be posted here for
information purposes. EPA expects that, over time, the testing of new HPV chemicals will
become routine, and companies may wish to test new HPV chemicals as they appear.
In keeping with that eventual goal, EPA is posting the 1994 List of HPV Additions, which
contains about 500 organic HPV chemicals which were newly reported as HPV in the 1994
IUR and are thus not part of the HPV Challenge Program at this time. This list is being
provided particularly for use by companies who desire to propose categories of chemicals
for testing and wish to include chemicals from the 1994 list in their category definitions. In
some cases, companies or consortia have sponsored chemicals that are not on either the
HPV Challenge Program Chemical List or the 1994 List of HPV Additions. A list of these
chemicals, called "Additional Chemicals Sponsored Under the HPV Challenge Program" is
also available.
Proprietor
Contact Information
Each list contains the Chemical Abstract Services (CAS) registry number, which is a unique
identification number assigned to a chemical; an indicator variable signifying whether the
chemical falls outside the scope of the HPV Challenge Program; the chemical name; the
chemical sponsorship status; and the sponsor commitment information. The explanations of
the various values used in the indicators and status columns can be viewed under the "How
to Use the Lists" button. Searches for CAS numbers, chemical names, indicators, chemical
sponsorship status, and sponsor commitment status may be conducted using the "Search"
function. Lists may be downloaded in either Portable Data Format (PDF) or database format
(DBF), (description from website)
EPA's Office of Pollution Prevention and Toxics (OPPT)
General Contact Information for the High Production Volume Challenge Program
Administrator
US Environmental Protection Agency
P.O. Box 1473
Merrifield, VA22116
Attention: Chemical Right-to-Know Program
By Phone:
(202) 564-4770
chem.rtk@epa.gov
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Name, CASRN, HPV Challenge status
This source is considered relevant for the CCL Universe because it is a list and contains
information on production volume, which may indicate potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/opptintr/chemrtk/hpvchmlt.htm
Data Source Name
Human Exposure Database System (HEDS)
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
92
HEDS is a web-based data system containing human exposure studies. It is designed to
provide data sets, documents, and metadata for human exposure studies for a variety of
contaminants in several media that can be easily accessed. HEDS allows users to download
unanalyzed data sets for analysis, it does not provide interpretations or synthesis of
exposure data. Currently, HEDS is limited to data from the National Human Exposure
Assessment Survey (NHEXAS) program, but more studies may be available through the
system in the future, (description from website)
EPA Office of Research and Development
Carry W. Croghan, HEDS Database Manager
U. S. Environmental Protection Agency
Human Exposure & Atmospheric Sciences Division
MD-E210C
Research Triangle Park, NC 27711
919-541-3184
Croghan.Carry@epa.gov
Contaminant Class, Sampling Method, Sampling Device, Sample Type Code, Concentration,
Qualifier, Method Det. Limit, Data Quality Flag, State, County, Samp. Location, Household
ID, Respondent*, Sample ID, Samp. Start Date, Samp. End Date
This source is considered relevant for the CCL Universe because it contains information that
is related to potential exposure.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.epa.gov/heds/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Idaho Toxic and Hazardous Substances - Idaho Division of Building
Safety
100
The Idaho General Safety and Health Standards have been compiled with the purpose of
consolidating all safety and occupational health standards into one book as guidelines. It is
also the intent that the safety standards contained herein be at least as effective as those
adopted by the Occupational Safety and Health Administration.
The use and exposure to toxic and to hazardous substances shall conform to all other
applicable requirements of this standard, as well as the following provisions. Nothing in this
standard shall be construed to prohibit better or otherwise safer conditions than specified
herein, (description from website)
Idaho Division of Building Safety and Idaho Industrial Commission
1090 E. Watertower St.
Meridian, ID 83642
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Ph (208) 334-3950
Substance, CAS RN, Limits for air contaminants, Material, 8-hour time weighted average,
Acceptable ceiling concentration, Concentration, Maximum duration
This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source is redundant with OSHA PELs (source 234), which is a more comprehensive
source.
This source meets retrievability criteria because it is in tabular format.
http://www2.state.id.us/dbs/safetv code/300.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Incidence and Prevalence Database (IPD) - Timely Data Resources
101
The Incidence and Prevalence Database provides global incidence, prevalence, morbidity,
comorbidity, cost data, symptoms and many other health issues for over 4,700 diseases
and procedures. Analysts review hundreds of medical journals, trade journals, audits, on-line
databases, registries, and market investment reports each month and summarize the data
into our Article Reviews. Full source citations are provided for each review. It also compiles
data from the most recent surveys of the National Center for Health Statistics (NCHS) in
Trend Data reports, (description from website)
Timely Data Resources, Inc.
Timely Data Resources, Inc.
107 Washburn Avenue
Capitola, CA 95010
Telephone: (408) 245-0673
Fax: (408) 245-0674
Email: support@tdrdata.com
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.tdrdata.com
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Indirect Additives Database
102
The Indirect Additives database contains administrative information (name, CAS number,
Federal Register regulation numbers, and Priority-based Assessment of Food Additives
(PAFA) database numbers) on over 3,000 substances indirectly added to foods. This list
includes substances used in food-contact articles, including adhesives and components of
coatings, paper and paperboard components, and adjuvants and production aids, (description
paraphrased from website)
FDA - Center for Food Safety and Applied Nutrition; CFSAN, Office of Food Additive
Safety
CFSAN Outreach and Information Center
Center for Food Safety and Applied Nutrition
5100 Paint Branch Parkway (HFS-555)
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College Park, MD 20740
Toll-Free Information Line:
1-888-SAFEFOOD (1-888-723-3366)
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
CFSAN Name, CASRN, Regulation Number
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.cfsan.fda.qov/~dms/opa-indt.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Infectious Disease Information
103
The CDC has indexed over 500 resources concerning infectious disease, including
descriptions of viral, bacterial, and protozoan agents. Because the summaries are from
diverse sources, they do not follow a specific format. Generally, health effects,
transmission patterns, disease prevalence, at-risk groups, and treatment are described.
CDC
Office of Health Communication
National Center for Infectious Diseases
Centers for Disease Control and Prevention
MailstopC-14
1600 Clifton Road
Atlanta, GA 30333
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/ncidod/diseases/index.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Information Collection Rule (ICR) Federal Database
98
The ICR database contains research data on pathogens in drinking water sources (e.g.,
lakes, reservoirs, etc.), indicators of fecal contamination (e.g., Total Coliform, Fecal
Coliform, and E. coli), amount of disinfectant and presence of disinfection byproducts in
treated drinking water, and the effectiveness of certain treatment technologies. Pathogens
covered include Cryptosporidium, Giardia, and viruses. Disinfection byproducts covered
include total trihalomethanes, bromate, chlorite, and haloacetic acids. Summary reports on
microbial and disinfection byproduct data at national, state, and water system levels can be
retrieved via the database. Data for the database was collected between 1997 and 1998.
(description from website)
EPA Office of Ground Water and Drinking Water
Technical Support Center:
U.S. EPA
26 Martin Luther King Drive
Cincinnati, Ohio 45268
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Phone: 513-569-7948
Fax: 513-569-7191
enviromail@epamail.epa.gov
DBP Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/enviro/html/icr/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Information System for Hazardous Organics in Water
270
ISHOW was sponsored by the Office of Toxic Substances of the US Environmental
Protection Agency. The database covers six types of physical property data for chemical
substances with bibliographic references to the original sources. Not all properties are
recorded for all substances.
SUBJECT COVE RAGE:
Chemical name identification
CAS Registry Numbers
Bibliographic references
Melting point
Boiling point
Vapor pressure
Water solubility
Log partition coefficient
Acid dissociation constant
(description from website)
National Information Services Corporation (NISC)/EPA
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Name, CASRN, Bibliographic references, MP, BP, BP, Water solubility,Log partition
coefficient, Acid dissociation constant
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
Source URL
http://www.nisc.com/cis/details/ishow.htm
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Integrated Risk Information System (IRIS)
108
IRIS is a toxicology data file on both EPA's website and on the National Library of Medicine's
(NLM) Toxicology Data Network (TOXNET®). It contains data in support of human health
risk assessment. It is compiled by the U.S. Environmental Protection Agency (EPA) and
contains over 500 chemical records. IRIS data, focusing on hazard identification and dose-
response assessment, is reviewed by work groups of EPA scientists and represents EPA
consensus. Among the key data provided in IRIS are EPA carcinogen classifications, unit
risks, slope factors, oral reference doses, and inhalation reference concentrations.
EPA Office of Research and Development; ORD, National Center for Environmental
Assessment
IRIS Representative
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax: (301)480-3537
Telephone: (301)496-1131
e-mail: toxmail@toxnetmail.nlm.nih.gov
IRIS
c/o ASRC
6301 Ivy Lane, Suite 300
Greenbelt, MD 20770
U.S. EPA Risk Information Hotline at telephone 1-301-345-2870, or fax to 1-301-345-2876, or
email to Hotline.IRIS@epamail.epa.gov
Name, Synonyms, CASRN, RfC, RfD, SF(i,o), UR(i,o), NO(A)EL, LO(A)EL, BMC/D, BMDL,
Critical effect
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets all considerations because it is peer reviewed.
The toxicological data for this source are available in tabular format from ITER (#110) and
RAIS-Health Effects (#178). Hence there is some overlap and redundancy, but each also
provide additional information not available elsewhere.
This source contains monographs that were not formatted for automated retrieval. However,
the toxicological data from this source have been compiled for electronic retrieval in ITER,
and were obtained from there. IRIS monographs were used to confirm the IRIS/ITER data.
http://www.epa.gov/iris/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Integrated Taxonomy Information System
104
ITIS is a collaboration among the U.S., Mexican and Canadian governments, and nonprofit
partner organizations, to create a comprehensive and consistent taxonomic catalog. An
interesting feature is the reference to experts for particular organisms. The Taxonomic
Resources and Expertise Directory (TRED) is searchable by expert or organism.
Partnership based at the USDA
Dr. Michael Ruggiero, Director
Integrated Taxonomic Information System (IT IS)
c/o Smithsonian Institution/NMNH MRC - 0180
Type of Data Elements
Relevance Explanation
Washington, DC 20560-0180
Phone:202-786-3117
fax: 202-786-2934
ruggiero.michael@nmnh.si.edu
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.itis.usda.gov/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
International Agency for Research on Cancer (IARC) - Summaries
and Evaluations
204
In 1969, the International Agency for Research on Cancer (IARC) initiated a programme on
the evaluation of the carcinogenic risk of chemicals to humans involving the production of
critically evaluated monographs on individual chemicals. In 1980 and 1986, the programme
was expanded to include evaluations of carcinogenic risks associated with exposures to
complex mixtures and other agents.
The objective of the programme is to elaborate and publish in the form of monographs
critical reviews of data on carcinogenicity for agents to which humans are known to be
exposed and on specific exposure situations; to evaluate these data in terms of human risk
with the help of international working groups of experts in chemical carcinogenesis and
related fields; and to indicate where additional research efforts are needed, (description from
website)
International Agency for Research on Cancer
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Name, CASRN, IARC Cancer Class
This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of INTOX (source 105).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/iarc.html
Data Source Name
Identification Number
International Agency for Research on Cancer (IARC) Monographs
96
Data Source Description
Proprietor
Contact Information
The IARC "publishes authoritative independent assessments by international experts of the
carcinogenic risks posed to humans by a variety of agents, mixtures and exposures." In the
first 75 volumes of this monograph series, 839 agents have been evaluated. Each
monograph consists of a brief description, where appropriate, of the potential exposure to the
agent or mixture, by providing data on chemical and physical properties, methods of
analysis, methods and volumes of production, use and occurrence. For exposure
circumstances, a history and description of the exposure are given. Then, the relevant
epidemiological studies are summarized. Subsequent sections cover evidence for
carcinogenicity obtained in experimental animals, and a brief description of other relevant
data, such as toxicity and genetic effects, (description from website)
International Agency for Research on Cancer
lARCPress
WHO-IARC Office
1775 K Street NW, Suite 480
Washington DC, 20006, USA
Fax: + 1 202223 1782;
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
E-mail: IARC Press (iarcpress@who.int)
Summary of Data Reported and Evaluation, Exposure data, Human carcinogenicity data,
Animal carcinogenicity data, Other relevant data, Overall evaluation, Previous evaluations
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
The monographic information in this source is not retrievable; however, the list of
contaminants and their cancer groups is retrievable and will be used for the CCL Universe.
IARC is a unique and exceptional source and is included to supplement the CCL Universe.
http://www-cie.iarc.fr/monoeval/grlist.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
International Bibliographic Information on Dietary Supplements
(IBIDS) - NIH
97
The International Bibliographic Information on Dietary Supplements (IBIDS) database
provides access to bibliographic citations and abstracts from published, international,
scientific literature on dietary supplements. The Office of Dietary Supplements (ODS) at the
National Institutes of Health produces this database to help consumers, health care
providers, educators, and researchers find credible, scientific information on a variety of
dietary supplements including vitamins, minerals and botanicals. IBIDS was developed and
is maintained through an interagency partnership with the Food and Nutrition Information
Center, National Agricultural Library, U.S. Department of Agriculture, (description from
website)
National Institutes of Health
Office of Dietary Supplements
National Institutes of Health
6100 Executive Blvd., Room 3B01, MSC 7517
Bethesda, Maryland 20892-7517
Tel: (301)435-2920
Fax: (301)480-1845
E-mail: ods@nih.gov
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ods.od.nih.gov/databases/ibids.html
Data Source Name
Identification Number
Data Source Description
Proprietor
International Chemical Safety Cards (ICSCs) - IPCS/WHO/ILO
99
"An ICSC summarizes essential health and safety information on chemicals for their use at
the "shop floor" level by workers and employers in factories, agriculture, construction and
other workplaces." Available for over 100 chemicals, ICSCs consist of a series of standard
categories, including acute hazards/symptoms, routes of exposure, and physical properties.
(description from website)
International Programme for Chemical Safety, World Health Organization
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH (1-800-356-4674)
Fax: 1-513-533-8573
Types of hazard/exposure, Acute hazards/ symptoms, Spillage disposal, Storage, Packaging
and Labelling, Prevention, First aid/ Fire fighting, Molecular Mass, Chemical formula,
Synonyms, Routes of Exposure, Physical Dangers, Inhalation Risk, Chemical Dangers,
Effects of Short-term Exposure, Effects of Long-term Exposure or repeated exposure,
Occupational exposure limits, Melting point, Density, Solubility, Vapor pressure, Log Kow,
This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of INTOX (source 105).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/niosh/ipcs/nicstart.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
International Cosmetic Legal and Regulatory Database - The
Cosmetic, Toiletry, and Fragrance Association (CTFA)
43
According to the web site, "the database is comprised of basic health laws, cosmetic
regulations, and other government rules governing cosmetic products for over 60 countries.
It also has a separate ingredient database which compares ingredient restrictions and use
requirements for all covered countries."
Cosmetic, Toiletry, and Fragrance Association
The Cosmetic, Toiletry, and Fragrance Association
1101 17th Street, NW, Suite 300
Washington D.C. 20036-4702
telephone: (202)331-1770
fax:(202)331-1969
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.ctfa-international.org/brochure.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
International Pharmaceutical Abstracts (IPA)
106
IPA includes bibliographic information covering pharmaceutical and health-related literature.
Literature coverage includes over 750 pharmaceutical, medical, and health-related journals
published since 1970. Specific topics include adverse drug reactions and toxicity,
pharmaceutics, drug evaluations and interactions, drug metabolism and body distribution,
drug stability, environmental toxicity, and related health topics.
Silver Platter; 'American Society of Health-System Pharmacists
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
333 Seventh Avenue
20th Floor
New York, NY 10001
Telephone: 646-674-6300
Toll Free in US: (800)-950-2035
Fax: 646-674-6301
E-mail: sales@ovid.com
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.ovid.eom/site/catalog/DataBase/109. isp?top=2&mid=3&bottom=7&subsection=10
Data Source Name
Identification Number
Data Source Description
International Register of Potentially Toxic Chemicals (IRPTC PC)
Data Profiles - UNEP Chemicals
109
United Nations Environment Programme (UNEP) Chemicals is the center for all chemicals-
related activities of the United Nations Environment Programme. This database contains
profiles for approximately 8,000 individual chemicals. It covers a complete range of the
physico-chemical properties and major endpoints such as environmental fate, mammalian
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
toxicity, ecotoxicity, evaluations from national and international peer reviewed sources, and
legislation.
(description from website)
United Nations Environment Programme; UNEP, Division of Technology, Industry, and
Economics
James B. Willis, Director
UNEP Chemicals (IRPTC)
Chemin des Anemones
Case postale 365, CH-1219 Chatelaine
Geneva, Switzerland
Tel.: +41-22-979-9111
Fax: +41-22-797-3460
E-mail: irptc@unep.ch
www: http://irptc.unep.ch/irptc
Environmental fate, Production, Mammalian Toxicity
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www-caer.nies.ao.ip/cger-e/db/info-e/lnfoDBWeb/db/irptc.htm
Data Source Name
Identification Number
Data Source Description
International Toxicity Estimates for Risk (ITER) Database
110
ITER is a free Internet database of human health risk values for over 600 chemicals of
environmental concern from several organizations worldwide. ITER is the only database that
provides this data in a table format that allows side-by-side comparisons of risk values from
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different organizations. Below the table is a synopsis that includes an explanation for any
differences among the organizations' values. ITER provides links to these organizations for
more detailed information. ITER currently contains data from:
Agency for Toxic Substances and Disease Registry (ATSDR)
ATSDR derives minimal risk levels (MRLs), which are found in the Agency's Toxicological
Profiles. Nearly all of the data from ATSDR's Toxicological Profiles are now on ITER; the
remaining ATSDR sections are flagged to indicate that the data are being prepared.
Health Canada
Health Canada develops Tolerable Intakes/Concentrations and Tumorigenic
Doses/Concentrations for Priority Substances under the Canadian Environmental Protection
Act (CEPA). These risk values for Health Canada are included on ITER.
International Agency for Research on Cancer (IARC)
IARC evaluates the cancer weight of evidence for chemicals over a wide range of human
exposures and classifies chemicals according to potential for carcinogenicity. The results of
IARC analyses are published Monographs. lARC's cancer classification categories refer only
to the strength of the evidence that an exposure is carcinogenic and not to the extent of its
carcinogenic activity (potency) nor to the mechanisms involved.
National Institute of Public Health and the Environment (RIVM), The Netherlands
RIVM develops human-toxicological risk limits (i.e., maximum permissible risk levels, MPRs)
for a variety of chemicals based on chemical assessments that are compiled in the
framework of the Dutch government program on risks in relation to soil quality. The MPRs
updated in 2001 are currently being added to ITER.
U.S. Environmental Protection Agency (EPA )
EPA derives risk values called reference concentrations (RfCs), reference doses (RfDs)
and cancer assessments. All of these risk values from EPA's Integrated Risk Information
System (IRIS) are included on ITER.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Independent parties whose risk values have undergone peer review
Risk values developed by other parties (e.g. industry, consulting groups, or universities) are
included on ITER (under the ITER column) after they have undergone an independent peer
review (http://www.tera.org/peer). This independent peer review is typically convened by
TERA through its Peer Review Program, and if the expert panel concurs with an assessment,
it may be made available to the public on the ITER database. Over two-dozen independent
risk values have been included on ITER, and are compared with the risk values from other
organizations. These independent values can only be found on ITER. (description from
website) ITER is also available from NLM as part of its TOXNET suite of databases.
TERA - Toxicology Excellence for Risk Assessment / NLM
1757 Chase Avenue
Cincinnati OH 45223
Phone:513-542-7475
Fax:513-542-7487
Email: TERA@TERA.org orwullenweber@tera.org
Name, CASRN, Critical effect, Cancer risk, Slope factor, MRL, RfD, RfC, TC(A), TDI,
RSC, RSD, LO(A)EL, NO(A)EL, TumCx, TumDx, TC05, TC01, TD05, Tl, TC, Risk Value,
This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.tera.org/iter
Data Source Name
Identification Number
Data Source Description
INTOX Databank - IPCS
105
The IPCS INTOX Package is a computerized poisons information package which is designed
to assist poison centres, health ministries and other related institutions to develop and
strengthen their capabilities for the efficient management of information relating to
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Proprietor
Contact Information
Type of Data Elements
poisoning, national product registration and chemical incidents.
The IPCS INTOX Package consists of the IPCS INTOX Data Management System and the
IPCS INTOX Databank. The Data Management System is a poisons information database
management software system, whilst the Databank is a collection of documents on
poisonous substances. Together they provide information on industrial chemicals,
Pharmaceuticals, household products, agricultural chemicals and plant, fungal and animal
toxins, as well as other agents commonly responsible for poisoning. This global, multilingual
package provides information on poisons and facilitates the management of information and
communication between poison information centres and inquirers.
(description from website)
IPCS
Canadian Centre for Occupational Health and Safety
135 Hunter Street East
Hamilton, ON, Canada L8N 1M5
1-800-668-4284
Contains EHC monographs, ICSCs, PIMs, and IARC Summaries and Evaluations, Pesticide
Data Sheets. Data elements in CHEMINFO files: Name, Synonyms, CASRN, other IDs,
Molecular formula, Structure, Appearance and odor, Odor threshold, Uses, Flash point, Lower
and upper flammable and explosive limits, Autoignition temperature, Sensitivity to
mechanical impact and static charge, MW, MP, BP, Relative density (specific gravity),
Water solubility, Other solubilities, Partition coefficient, pH value, Vapor density, VP,
Saturation vapor concentration, Evaporation rate, Critical temperature, Critical pressure,
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Viscosity, Surface tension, LC/LDx, Short-and long-term effects, Carcinogenicity,
Mutagenicity, Teratogenicity/embryotoxicity, Reproductive tox
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is redundant with IARC - Summaries and Evaluations. INTOX is a subscription
source and IARC is independently and publicly available.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.intox.org
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
IPCS/EC Evaluation of Antidote Series
107
The IPCS/EC Evaluation of Antidotes Series Provides definitive and authoritative guidance
on the use of antidotes to treat poisoning. The International Programme on Chemical Safety
(IPCS) and the Commission of the European Union (EC) are jointly undertaking a major
project to evaluate antidotes used clinically in the treatment of poisoning. The aim of this
project is to identify and evaluate for the first time in a scientific and rigorous way the
efficacy and use of a wide range of antidotes. This series summarises and assesses, on an
antidote-by-antidote basis, their clinical use, mode of action and efficacy. The aim is to
provide an authoritative consensus statement which will greatly assist in the selection and
administration of an appropriate antidote. This scientific assessment is complemented by
detailed clinical information on routes of administration, centra-indications and precautions.
The series collates a wealth of useful information which will be of immense practical use to
clinical toxicologists and all those involved in the treatment and management of poisoning.
(description from website)
International Programme for Chemical Safety, Commission of the European Union
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Field, Introduction, Name and chemical formula, Physico-chemical properties,
Pharmaceutical formulation and synthesis, Analytical methods, Shelf life, General
properties, Animal studies, Toxicology, Volunteer studies, Pharmacodynamics,
Pharmacokinetics, Clinical studies - clinical trials, Clinical studies - case reports, Route of
administration, Summary of evaluation and recommendations, Model information sheet,
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
References, Historical review, Summary of analytical aspects, References, Mechanism of
toxicity, Laboratory findings, Treatment, Qualitative methods, Quantitative methods
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of INTOX (source 105).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/antidote.html
Data Source Name
Joint Expert Committee on Food Additives (JECFA) - Monographs
and Evaluations
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
111
Toxicological evaluations of food additives and contaminants and of residues of veterinary
drugs in food, produced by the Joint WHO/FAO Expert Committee on Food Additives
JECFA, are used by the Codex Alimentarius Commission and national governments to set
international food standards and safe levels for protection of the consumer. The monographs
provide the toxicological information upon which the JECFA makes its evaluations. These
monographs are prepared by scientific experts and peer reviewed at the JECFA meetings.
(description from website)
World Health Organization, Food and Agriculture Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Summary of evaluations, Recommended dietary allowance, Carcinogenicity, Mutagenicity,
Reproduction, Teratogenicity, Acute Toxicity, Short term studies, Long-term studies,
Observations in humans, Immune response, Ototoxicity, Microbiological effects
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Data Source Name
Identification Number
Data Source Description
Joint Meeting On Pesticide Residues (JMPR) - 2001 Inventory of
Pesticide Evaluations
112
This inventory summarizes evaluations of pesticides that have been performed by the Joint
FAO/WHO Meeting on Pesticide Residues (JMPR) and other assessments of pesticides by
IPCS and other programmes in WHO. It does not include the maximum residue limits (MRLs)
that have been recommended by JMPR.
The inventory itself lists relevant documents that have been published and summarizes the
acceptable daily intakes (ADIs) and provisional tolerable daily intakes (PTDIs) that have
been established by JMPR. It should be noted that the first entry under each pesticide is the
one that is currently applicable. JMPR has not evaluated those pesticides that do not
include the JMPR evaluations heading.
Annex 1 defines the codes and explains the abbreviations used in Table 1 and Annex 2,
which includes links to documents that are available electronically, lists the reports and other
documents resulting from the Joint Meetings on Pesticide Residues that have been held to
date. Many of the older publications that are listed are out of print but are available
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Proprietor
Contact Information
electronically. Addresses for obtaining documents and publications are provided in Annex 1.
Annex 3 provides further information on several specific pesticides that are referenced in
the inventory, (description from website)
World Health Organization, Food and Agriculture Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, CASRN, ADI
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.inchem.ora/documents/impr/impeval/impr2002.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Joint Meeting On Pesticide Residues (JMPR) - Monographs of
Toxicological Endpoints
113
Toxicological evaluations of pesticides, produced by the WHO/FAO Joint Meeting on
Pesticide Residues JMPR , are used by the Codex Alimentarius Commission and national
governments to set international food standards and safe levels for protection of the
consumer. The monographs provide the toxicological information upon which the JMPR
makes its evaluations. These monographs are prepared by scientific experts and peer
reviewed at the JMPR meetings, (description from website)
World Health Organization, Food and Agriculture Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Name, CASRN, Formula, Structure, ADI, RfD, DWGLs, pTDI, RfD, LDx, NO(A)EL,
LO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/impr.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Label Review Manual
264
The Label Review Manual was developed as a training tool and guidance for reviews of
pesticide product labels. The goals are to improve the quality of labels and increase the
consistency of reviews. The manual describes what a pesticide is and what constitutes a
label and labeling and also provides step-by-step instructions for reviewing a pesticide label
and how unique issues have been handled in the past, (description from website)
EPA, OPP
Office of Pesticide Programs at 703-308-9068
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Type of Data Elements
General Labeling Requirements, Types of Label Review, Ingredient Statement, Use
Classification, Precautionary Labeling, Environmental Hazards, Physical or Chemical
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Hazards, Worker Protection Labeling, Directions for Use, Labeling Claims, Storage and
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.aov/oppfead1/labeling/lrm/
Data Source Name
Identification Number
Data Source Description
Laboratory Chemical Safety Summaries (LCSS) - Howard Hughes
Medical Institute and National Academy of Science
114
The Howard Hughes Medical Institute collaborated with the National Academy of Sciences in
making the 88 Laboratory Chemical Safety Summaries (LCSSs) prepared by the National
Research Council, Committee on Prudent Practices for Handling, Storage, and Disposal of
Chemicals in Laboratories.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The LCSSs provide concise critical discussions of the toxicity, flammability, reactivity, and
explosibility of 88 chemicals commonly used in scientific research laboratories. Directions
for handling, storage, and disposal and special instructions for first aid and emergency
response are given. Since many of these 88 chemicals are representative of a class of
potentially hazardous compounds, the LCSSs can also be used as guides to handling many
other compounds with related chemical structures. The LCSSs are designed especially for
laboratory workers, (description from website)
Howard Hughes Medical Institute, National Academy of Science
Howard Hughes Medical Institute
4000 Jones Bridge Road
Chevy Chase, MD 20815-6789
(301)215-8500
E-mail: webmaster@hhmi.org
Substance, Formula, Physical Properties, Odor, Vapor Density, Vapor Pressure, Flash Point,
Autoignition Temperature, Toxicity Data, Major Hazards, Toxicity, Flammability and
Explosibility, Reactivity and Incompatibility, Storage and Handling, Accidents, Disposal
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.hhmi.org/research/labsafe/lcss/
Data Source Name
Identification Number
Data Source Description
List of Bacterial Names with Standing in Nomenclature
115
The Society for Systematic and Veterinary Bacteriology in France maintains an up-to-date
online list of approved bacterial nomenclature. This source provides an alphabetically and
chronologically list of the nomenclature of bacteria as cited in the Approved Lists of
Bacterial Names, orvalidly published in the International Journal of Systematic Bacteriology
and in the International Journal of Systematic and Evolutionary Microbiology.
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Society for Systematic and Veterinary Bacteriology
J. Euzeby
Laboratoire de Bacteriologie
Ecole Nationale Veterinaire
23, chemin des Capelles
B.P. 87614
31076, Toulouse cedex 03, France
Fax:+ 33 5 61 193975
E-mail: J.P. Euzeby
Genera and taxa above the rank of genus up to and including class, Type species,
Reference, Original article in IJSEM Online, Note, List of Candidatus, Taxa above the rank
of class, All validly published names, Culture collections of prokaryotes, Some bacterial
names without standing in nomenclature, Definitions and abbreviations
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.bacterio.cict.fr/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Mallinckrodt Baker, Inc., Material Safety Data Sheets
286
MALLIN is a collection of approximately 1,975 material safety data sheets prepared by by
Mallinckrodt Baker, Inc., of St. Louis, Missouri, and Phillipsburg, NJ, in accordance with
guidelines issued by the US Occupational Safety and Health Administration (OSHA). One
chemical substance is covered in each record.
SUBJECT COVERAGE:
Chemical identification
Regulations
Health and fire hazards
Physical property data
Reactivity data
Spill and disposal procedures
CAS Registry Numbers
Protective equipment
First aid information
Storage and handling data
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Availability of Treatment, Health Effects, PEL, Infectious Dose, Mortality,
Physical/Chemical Properties, Toxicological Information, Reproductive Toxicity,
This source is considered relevant for the CCL Universe because it contains environmental
fate data, that may be used as an indicator of potential occurrence.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.nisc.com/cis/details/mallin.htm
Data Source Name
Identification Number
Data Source Description
Master Summary Table for HPV Chemical Hazard Data Availability
Study
116
The Master Summary Table for the US High Production Volume (HPV) Chemical Hazard Data
Availability Study contains information on whether or not data on six hazard endpoints are
publicly available for 2863 US HPV organic chemicals (68 inorganic HPV chemicals were
deleted from the original database of 2931 HPV chemicals reported under the 1990 Inventory
Update Rule). The six hazard endpoints (acute toxicity, chronic toxicity, teratogenicity or
developmental and reproductive toxicity, mutagenicity, ecotoxicity, and environmental fate)
comprise the "Screening Information Data Set" (SIDS) test battery established by the
Organization for Economic Cooperation and Development (OECD, 1998a).
Variable names for each column are shown in the first row of the database. The remaining
rows contain the information on hazard data availability for the chemicals. The first column
(CAS.NO) contains the Chemical Abstract Services registry number, which is a unique
identification number assigned to a chemical. The name of the chemical is displayed in the
second column (CHEMICAL). An "X" is shown in the third column (ACUTE), if EPA was able
to locate any information on acute toxicity testing. Columns 4 (CHRONIC), 5 (TERARE), 6
(MUTAGEN), 7 (ECOTOX), and 8 (FATE) are also marked with an "X" if hazard data were
located for chronic toxicity, teratogenicity or developmental/reproductive toxicity,
mutagenicity, ecotoxicity, and environmental fate, respectively. The total number of six
hazard test data endpoints located for each chemical is shown in Column 10 (TOTAL).
Some 277 of the 2863 US HPV chemicals are part of the ongoing OECD SIDS international
program. Some of the SIDS testing is complete, but many of those studies have not yet
been entered into publicly accessible databases, although all of the information will be
available in the future as those databases are updated. A "C" or "U" is marked in Column 9
(SIDS) if the chemical is part of the OECD SIDS testing program. A "C" indicates that
testing has been completed, and a "U" denotes that testing is ongoing. Copies of completed
SIDS dossiers are available through the United Nations Environmental Programme (UNEP,
1996). The Master Summary Table will be updated to include the SIDS information once the
hazard data become available.
Proprietor
Contact Information
Additional columns in the table indicate whether the chemical is a high release TRI chemical
(TRI HIGH), whether the chemical is on the 1995 TRI database (TRI), whether an OSHA PEL
(OSHA PEL) is in place for the chemical, and whether the chemical is a consumer product
chemical (CPC) listed in EPA's Source Ranking Database, (description from website)
EPA, OPPT
US Environmental Protection Agency
Chemical Information and Testing Branch
1200 Pennsylvania Avenue, NW
Mail Code 7405M
Washington, DC 20460
202-564-4780
Fax: 202-564-4765
E-mail: ccd.citb@epa.gov
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, CASRN, SIDS and TRI status, Availability of toxicity data
This source is considered relevant for the CCL Universe because it contains a list that is
related to occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant, as it is wholly available as part of the HPV Chemical List (source
93) and CUS/IUR (source 33).
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/opptintr/chemtest/hazchem.htm
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Material Safety Data Sheets (MSDS)
124
Material Safety Data Sheets for more than 200 infectious agents have been produced. The
type of information provided and technical language used are geared toward laboratory
personnel. Basic disease descriptions, infective doses, and decontamination procedures are
described.
Health Canada
Health Canada
A.L. 0900C2
Ottawa, Canada
K1AOK9
Telephone: (613)957-2991
Fax:(613)941-5366
TTY: 1-800-267-1245
wm-pphb-dgspsp@hc-sc.gc.ca
Name, Synonym, Characteristics, Pathogenicity, Epidemiology, Host range, Infectious
Dose, Mode of transmission, Incubation period, Communicability, Reservoir, Zoonosis,
Vectors, Drug susceptibility, Drug resistance. Survival outside host
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.hc-sc.ac.ca/pphb-dgspsp/msds-ftss/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Mediscover
117
Mediscover provides medical news and information concerning emerging diseases and
treatments. Although the site presents news concerning infectious diseases in general, its
focus is on vaccines.
International Medical Press
info@mediscover.net
Data elements for microbial contaminants
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.mediscover.net
Data Source Name
Identification Number
Data Source Description
MEDLINE
278
Medline is the electronic version of Index medicus, a comprehensive index of scientific
periodical literature in the medical sciences compiled by the National Library of Medicine. It
includes all medically related areas of biology and all medical specialties, and is particularly
strong in molecular biology.
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Medline indexes journal articles and chapters in symposia, not whole books, including more
than 3800 journals and other periodical publications. Medline covers the literature from 1966.
Most current articles have abstracts. Coverage is worldwide, but most items are in English or
have English abstracts. There is systematic indexing for standardized medical vocabulary,
and extensive use of acronyms, enzymes, gene names, and names of key reagents.
The CIS subset of NIOSHTIC® records are required to provide a CAS Registry Number and
discuss one or more of the following subjects: Hazmat, Biodegradation, Environmental Fate,
Gastrointestinal Absorption, Toxicity, Carcinogenicity, Turmorigenicity, Mutagenicity,
Teratogenicity, Acid Dissociation, Bioconcentration Factor, Effluent Concentrations,
Photooxidation, Ultraviolet Absorption, Volatilization, Superfund Sites, or Occupational
Safety, (description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com/cis/details/medline.htm
Data Source Name
Identification Number
Michigan State Ribosomal Database Project
118
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This database catalogs over 30,000 ribosomal ribonucleic acid (rRNA) sequences from
diverse organisms, including pathogens, because such sequences are conserved and can be
used to determine phylogenetic relationships.
Michigan State University researchers (funded by the National Science Foundation (NSF)
and DOE)
Ribosomal Database Project
2225A Biomedical and Physical Sciences Building
Michigan State University
East Lansing, Ml, 48824
(517) 432-4998 (phone)
(517) 353-8957 (Microbiology Dept fax)
e-mail: rdpstaff@msu.edu
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://rdp.cme.msu.edu/html/index.html
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
MicrobeLibrary
119
MicrobeLibrary is a catalogued collection of peer reviewed teaching resources related to
microbial biology. Four groups of resources are available: visual, curriculum, articles, and
reviews. The MicrobeLibrary is searchable portal providing a peer reviewed, web-based
collection of resources about the microbial world. The Library builds upon the scientific
expertise, intellectual creativity, and private collections of the 42,000 members of the
American Society for Microbiology (ASM) and other microbial researchers from around the
world, (description from website)
American Society for Microbiology (funded by NSF)
ASM's MicrobeLibrary
Education Department
1752 N Street N.W.
Washington, DC 20036
Phone: 202-942-9282
Fax: 202-942-9329
MicrobeLibrary@asmusa.org
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.microbelibrarv.org/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Microbiology Abstracts, Section B: Bacteriology - Cambridge
Scientific Abstracts
120
The well-rounded, medically-oriented coverage in Bacteriology makes it possible for
researchers and clinicians to keep up with the constant changes in this explosive field. With
topics ranging from bacterial immunology and vaccinations to diseases of man and animals,
the journal provides access to far-reaching clinical findings as well as all aspects of pure
bacteriology, biochemistry, and genetics. General microbiologists and bacteriologists aren't
the only specialists who turn to Bacteriology each month for important perspectives in the
field. The journal is also valuable to environmentalists, medical and veterinary laboratory
staff, agricultural researchers, cell biologists, geneticists, toxicologists, and many others.
Major areas of coverage include: Aggressins and toxins, Animal bacteriology, Antibacterial
agents, Antibiosis, Antibiotics, Cell structure and function, Culture
Ecology and distribution, Genetics and evolution, Human bacteriology, Identification,
Immunology, Invetebrate bacteriology, Methodology, Microbial symbiosis, Plasmids,
Predation, Taxonomy, Typing, (description from website)
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax: +1 301-961-6720
Email: sales@csa.com
Bibliographic information, Indexing terms, Abstracts
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation It meets considerations because it meets all NDWAC minimum data requirements.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.csa.com/csa/ids/databases-collections.shtml - environmental
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
MicrobioNet
121
Microbionet is an Australian for-profit corporation providing comprehensive information by
genus or by species for bacteria and, in the future, for viruses and protozoa. Available free
online are pathogen profiles that include classification, biochemistry, serology, genetics,
virulence factors, normal flora, pathogenicity, laboratory ID, and environmental, industrial,
and vaccine data. More comprehensive reviews are slated to become available to paying
members (this feature is currently under construction).
Sciencenet Multimedia Publishing House; Microbionet
Sciencenet Multimedia Publishing House Pty Limited
CAN 074 869 122
40 Hastings Road Hawthorn East, 3123, Victoria Australia
Attention: Barbara Wagstaff Chief Executive Officer
Tel:+61-3-9882-2665
Fax:+61-3-9882-6811
email: bmwag@planet.net.au
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Classification, Biochemistry, Genetics, Serology, Virulence Factors, Normal Flora,
Pathogens, Laboratory Diganosis of Infections, Environmental Aspects, Industial Uses,
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.sciencenet.com.au/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Morbidity and Mortality Weekly Report (MMWR) Surveillance for
Waterborne-Disease Outbreaks
122
EPA and the CDC have maintained a collaborative surveillance system for collecting and
periodically reporting data that relate to occurrences and causes of waterborne-disease
outbreaks. The surveillance system includes data about outbreaks associated with both
drinking water and recreational water. Surveillance summaries are based on State, territorial,
and local public health department reporting of waterborne-disease outbreaks, (description
from website)
CDC - National Center for Infectious Diseases
John W. Ward, M.D., Editor
Epidemiology Program Office MS C-08
Centers for Disease Control and Prevention
1600 Clifton Rd.
Atlanta, GA 30333
Fax:(404)639-4198
E-mail: mmwrq@cdc.gov
Waterborne-disease outbreaks associated with drinking water, Waterborne-disease outbreaks
associated with drinking water, by etiologic agent and type of water system, Waterborne-
disease outbreaks associated with drinking water, by type of deficiency and type of water
system, Waterborne-disease outbreaks of gastroenteritis associated with recreational water,
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
State, Month, Etiologic agent, Illness, Number of Cases, Source, Setting
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is redundant with FoodNet (source 74).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/mmwr/
Data Source Name
Identification Number
Data Source Description
Proprietor
Multicase
239
See CASE/MCase/MC4PC
Multicase
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
See CASE/MCase/MC4PC
See CASE/MCase/MC4PC
This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.
It does not meet considerations because there was no documentation on how the data were
This source is redundant, as it is the same as the Case model (source 238).
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a
http://www.multicase.com/products/prod01.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Municipal Water Use Database - Environment Canada
125
The MUD database is designed to provide easy access to basic data on municipal water and
wastewater. The 1999 database (spreadsheet) currently contains water and sewage systems
information from Canadian municipalities with populations over 1000. The total population of
these municipalities is 25 million out of a total 1999 Statistics Canada Census population of
30 million. The database is now "Up N Running", debugging and other tests have been
completed. The data are usually released as an Excel95 spreadsheet format, and can be
sorted into a variety of aggregations, including; Provincial, Regional, Hydrologic, population
size groups, and others.
Environment Canada
Mr. David Burke
Policy Analyst
Sustainable Water Use Branch
Environment Canada
Ottawa, Ontario K1AOH3
Tel.: (819)934-2486
Fax: (819)994-0237
E-mail: H2O@ec.gc.ca
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.ec.gc.ca/water/mud/en/index.cfm
Data Source Name
Identification Number
Data Source Description
National Ambulatory Medical Care Survey (NAMCS)
127
This survey, conducted annually by the CDC since 1989, provides national data on the
utilization and provision of ambulatory care services in hospital emergency and outpatient
departments. The information on pharmaceutical usage may be applicable for estimating
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Retrievability Explanation
Source URL
potential drinking water occurrence of these compounds.
CDC - National Center for Health Statistics
National Center for Health Statistics
3311 Toledo Road
Hyattsville, MD 20782
Phone:(301)458-4000
Patient visit file, Date of visit, Patient's age, Patient's sex, Reason(s) for the visit,
Physician's diagnoses, Medications provided or prescribed, New medication, Additional drug
characteristics, Generic name, Prescription status, Controlled substance status, Composition
status, Drug class, Ingredients, Major reason for the visit, Accidental injury or product-
related illness, Drug mention file, Medication/drug entry name, Entry status,
Diagnostic/screening services, Counseling/advice, Selected types of therapy, Does patient
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it is peer reviewed.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.cdc.aov/nchs/about/maior/ahcd/namcsdes.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Animal Health Reporting System (NAHRS)
126
This database, currently in development, is slated to record incidence of certain infectious
diseases among commercial livestock in all 50 states. Participation of state animal health
officials is voluntary, and no report has been published to date.
U.S. Animal Health Association (USAHA), the American Association of Veterinary Laboratory
Diagnosticians (AAVLD), and the U.S. Department of Agriculture's Animal and Plant Health
aphis.webmaster@aphis.usda.gov
Microbial outbreak-related data elements for microbial contaminants
This source does not meet relevance criteria because it contains only information on
microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.aphis.usda.gov/vs/ceah/
Data Source Name
National Cancer Institute Database of 3 Dimensional Chemical
Structures (NCI-3D)
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Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
135
Provides substructure searches on 126,554 compounds and SMILES notation (used for
Quantitative Structure Activity Relationships) for 237,771 compounds. Subsets of this
database have been screened for anti-tumor and anti-Human Immunodeficiency Virus (HIV)
properties with the Developmental Therapeutics Program (DTP) in vitro cell line, representing
60 human tumor cell lines.
National Library of Medicine - DSIS; Division of Specialized Information Services
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
tehip@teh.nlm.nih.gov
CASRN, molecular formula, structure, SMILES
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://chem.sis.nlm.nih.gov/nci3d/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Drinking Water Contaminant Occurrence Database (NCOD)
- 6-Year Data
136
The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
databases and provides summary statistics of national occurrence of regulated and
unregulated contaminants. The Six Year data set contains detects and concentration
statistics, as well as method reporting limit information, for the 61 chemicals on the Six Year
Review analysis for ground and surface water.
EPA Office of Ground Water and Drinking Water
Safe Drinking Water Hotline
Phone: 1-800-426-4791
Email: hotline-sdwa@epa.gov
Drinking Water Occurrence Concentrations
This source does not meet relevance criteria because it contains only information for
regulated contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.gov/safewater/data/ncod.html
Data Source Name
Identification Number
Data Source Description
National Drinking Water Contaminant Occurrence Database (NCOD)
- Round 1&2
137
The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
databases and provides summary statistics of national occurrence of regulated and
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
unregulated contaminants. This source contains detects and concentration statistics for the
76 chemicals on the Round 1 and 2 analysis for surface and ground water.
"The Round 1 dataset contains public water system monitoring sample results for 62 (then)
unregulated contaminants, generally collected between 1988 and 1992, from 40 states and
primacy entities. These data are from the first round of required monitoring of unregulated
contaminants. Round 1 data were stored in a database called the Unregulated Contaminant
Monitoring Information System (URCIS). The Round 2 dataset (the second round of
unregulated contaminant monitoring) contains public water system monitoring sample data
for 48 (then) unregulated contaminants, generally collected between 1993 and 1997, from 35
states and primacy entities. Round 2 data were obtained from the EPA Safe Drinking Water
Information System (SDWIS/FED)."
(description from website)
EPA Office of Ground Water and Drinking Water
Safe Drinking Water Hotline
Phone: 1-800-426-4791
Email: hotline-sdwa@epa.gov
Drinking water occurrence concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of unregulated contaminants in drinking water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.gov/safewater/data/ncod.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
National Drinking Water Contaminant Occurrence Database (NCOD)
- Unregulated Contaminant Monitoring Rule (UCMR)
233
The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
databases and provides summary statistics of national occurrence of regulated and
unregulated contaminants.
EPA uses data generated by the UCMR (1999) to evaluate and prioritize contaminants on the
EPA Contaminant Candidate List (CCL). The CCL is a list of contaminants EPA is
considering for possible new drinking water standards. Additional information on the rule is
available on the UCMR main page.
The occurrence data associated with the revised UCMR (1999) is meant to assist the
Agency in determining whether or not to regulate a certain contaminant. The UCMR (1999)
was designed to assess contaminant occurrence nationally. Therefore, extreme caution
should be used in any interpretation of data, which reflects only a subset of the entire
database. The monitoring is scheduled during the period from 2001 until 2003. So, any
interpretation of data before all the data are collected (probably mid-2004) may lead to false
conclusions.
EPA Office of Ground Water and Drinking Water
Safe Drinking Water Hotline
Phone: 1-800-426-4791
Email: hotline-sdwa@epa.gov
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
(description from website) Drinking Water Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in drinking water, demonstrating occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
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Source URL
http://www.epa.gov/safewater/data/ncod.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
National Environmental Data Index (NEDI)
129
The National Environmental Data Index (NEDI) provides direct access to environmental data
and information descriptions, and thereby, improves awareness of and facilitates access to
data and information holdings. The overall goal of the NEDI is to facilitate the use of the
widest possible range of environmental data and information to support curability to protect
human health, safety, and welfare; to maintain and restore ecological integrity; and to
sustain economic stability and growth. The NEDI will be a focus for identifying
environmental data and information holdings within the United States and ultimately,
internationally, (description from website)
National Oceanic and Atmospheric Administration
NOAA Environmental Information Services E/EIS
1335 East West Highway
Room 7226
Silver Spring MD 20910
Phone:301-713-0816
Fax:301-713-0819
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
www.nedi.gov
Data Source Name
Identification Number
Data Source Description
National Health and Nutrition Examination Survey (NHANES)
139
The most relevant portion of NHANES for screening potential drinking water contaminants is
the National Report on Human Exposure to Environmental Chemicals (NRHEEC).
Biomonitoring data include measurements of 27 chemicals, including pesticides (e.g.,
phthalates and organophosphates) and other prevalent chemicals (such as lead and
beryllium) in either the blood or urine of a small but national sample of the U.S. population.
Several databases and journal articles describing other studies (e.g., high blood pressure,
immunization status, and nutritional blood measures) conducted under NHANES III are
available. The NHANES VOC database contains relevant data for over 40 chemicals. Also
useful for occurrence and health effects for contaminant screening may be the General
Mortality tables. These tables include the causes of death for all age groups in the United
States and include waterborne disease outbreaks.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
CDC National Center for Health Statistics
National Center for Health Statistics
Hyattsville, MD 20782
Phone:(301)458-4000
CAS RN, Parameter, Detection limit, Number of samples, Mean, Median, 5th percentile,
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in either the blood or urine, providing an indicator of occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/nchs/nhanes.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Hospital Discharge Survey (NHDS)
141
NHDS has been conducted annually by CDC since 1965 and provides general summary
statistics of trends in hospital care, such as average age of patients, frequently prescribed
medications, and nature of illness, from patients who have stayed at the hospital for fewer
than 30 days. The data comprise a sample of the 270,000 available inpatient records from
about 500 hospitals nationwide. Information on prescribed medications may be of interest
from this survey, (description from website)
CDC - National Center for Health Statistics
National Center for Health Statistics
Hospital Care Statistics Branch
Hyattsville, MD 20782
Phone: (301)458-4321
Age, Sex, Race, Ethnicity, Marital Status, Admission and Discharge Dates, Discharge
status, Diagnoses, Procedures
This source is considered relevant for the CCL Universe because it contains information on
prescribed medications. These data might be used as a source of information on potential
occurrence of Pharmaceuticals.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of IPD (source 101).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.aov/nchs/about/maior/hdasd/nhds.htm
Data Source Name
Identification Number
National Human Adipose Tissue Survey (NHATS)
140
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
NHATS analyzed human adipose tissue specimens to monitor human exposure to potentially
toxic chemicals. A nationwide network of pathologists and medical examiners from 47
metropolitan statistical areas collected tissue specimens from cadavers and surgical patients
that were analyzed for organochlorine pesticides, PCBs, and volatile and semivolatile
organic compounds. NHATS contains biomonitoring data for over 150 chemicals, and
analyses for a variety of toxic compounds, using standardized protocols on composite
categorizations that represent nine regions and three age groups. More detailed information
is available in "Broad scan analysis of the FY82 National Human Adipose Tissue Survey
specimens" Volume 1-Executive Summary, EPA Document No. EPA-560/5-86-035,
Washington D.C., Phillips and Birchard, Arch. Environ. Contam. Toxicol., 21, 1991, pp. 159-
168. (description from website)
Also see: http://books.nap.edu/books/0309044375/html/index.html
This book provides a fairly comprehensive description of the process used for this survey.
EPA Office of Toxic Substances
OSCPweb@epa.gov
Chemical name, CAS RN, Year, Number of Analyses, Arithmetic/Geometric Mean, Lowest
Arithmetic/Geometric Mean, Number of Analyses with Lowest Arithmetic/Geometric Mean,
Highest Arithmetic/Geometric Mean, Number of Analyses with Highest Arithmetic/Geometric
Mean
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in human adipose tissue, providing an indicator of occurrence.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.aov/oscpmont/sap/1998/mav/edstac/appeng.pdf
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
National Human Exposure Assessment Survey (NHEXAS)
249
The National Human Exposure Assessment Survey program is designed to evaluate
comprehensive human exposure to multiple chemicals on a community and regional scale.
The focus of NHEXAS is on the exposure of people to environmental pollutants in their daily
lives. Samples were collected of the air that people breathe, the food that they eat, the
water and beverages that they drink, of the soil and dust around their homes, and of their
blood and urine. Preliminary results of Phase I of NHEXAS are reported in 15 journal articles
published in the September-October 1999 issue of the Journal of Exposure Analysis and
Environmental Epidemiology. The journal articles are summarized in Table 1. Seven of the
15 journal articles provide information that is applicable for inclusion in the Endocrine
Disrupter Priority-Setting Database. Altogether the seven journal articles provide data on 25
compounds and approximately 20 media. Table 2 lists the compounds and provides
information on the media for which data is reported for them, (from ERG data source memo)
Center for Disease Control, Environmental Health Laboratory
Edo Pellizzari
edp@rti.org
Tel: 919.541.6579
Fax: 919.541.6161
3040 Cornwallis Road
Post Office Box 12194
Research Triangle Park, NC 27709-219
http://www.rti.org/page.cfm?objectid=A892862B-ODBO-4405-BB30056DB2611983
Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of HEDS (source 92).
This source meets retrievability criteria because it is in tabular format.
http://www.epa.gov/heasd/edrb/nhexas.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
National Inorganics and Radionuclides Survey (NIRS)
144
NIRS was designed and conducted by EPA specifically to provide data on the occurrence in
ground water of a set of 42 radionuclides and inorganic chemicals (lOCs) being considered
for National Primary Drinking Water Regulations (NPDWRs). NIRS provides contaminant
occurrence data from a statistical sample comprised of 989 nationally representative
community public water systems served by ground water, in 49 states and Puerto Rico that
treat ground water for distribution. Samples were collected from the distribution system
subsequent to treatment. Each of these randomly selected public water systems was
sampled a single time between 1984 and 1986.
EPA OGWDW; The Cadmus Group, Inc.
Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
1:617-673-7000
F: 617-673-7001
Drinking Water Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
Error! Hyperlink reference not valid.
Data Source Name
Index
Identification Number
Data Source Description
Proprietor
Contact Information
National Institute for Occupational Safety and Health (NIOSH) -
of Occupational Health Guidelines for Chemical Hazards
143
Occupational Health Guidelines for Chemical Hazards summarize information for over 675
substances on names and synonyms: Permissible Exposure Limits in air, chemical, and
physical properties; and health hazards. In addition, these guidelines are revised when new
information is made available, or when deemed necessary, and the revised documents are
also available at the same web site. These guidelines may be of use when evaluating the
health effects of certain drinking water contaminants where inhalation exposure may be
relevant (as most workplace exposures are from inhalation during production of the
contaminant).
CDC National Institute for Occupational Safety and Health (NIOSH)
Centers for Disease Control and Prevention
1600 Clifton Rd
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Atlanta, GA 30333, USA
Tel (404) 639-3311
Public Inquiries (404) 639-3534 / (800) 311 - 3435
Formula, Structure, Appearance and odor,
Physical Data, Reactivity, Flammability, OSHA PEL, NIOSH REL, ACGIH TLV, Rationale
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.qov/niosh/chem-inx.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
National Institute of Enviornmental Health Sciences (NIEHS)
Reproductive Toxicology Group
142
The Reproductive Toxicology Group researches the adverse health effects of chemicals and
other environmental agents on fecundity, germ cell genetics, and development. The group
generates toxicity data through in-house research, and provides this data to regulatory
agencies and public health groups. The website provides an index of which environmental
agents have been researched, and in what capacity, (description from website)
NIEHS - Reproductive Toxicology Group; National Institute of Environmental Health and
Safety (NIEHS)
Robert E. Chapin, PhD
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
NIEHS
PO Box 12233
MD B3-05 Research Triangle Park, NC 27709
Phone 919/541-3474
Fax 919/541-4634
Email Chapin@niehs.nih.gov
Chemical Name, CAS number, Test
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://dir.niehs.nih.aov/dirtb/dirrtg/chemicalsstudiedindex2.htm
Data Source Name
Identification Number
National Nosocomial Infections Surveillance System (NNIS)
145
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This database is a national cooperative effort between the CDC and participating hospitals to
create a nosocomial (hospital-related) infections database. The database describes the
epidemiology of nosocomial infections, describes the antimicrobial resistance trends, and
can be used to produce infection rates. The program began in 1970, with approximately 315
hospitals participating and voluntarily surveying and reporting results to CDC at the
beginning of 2000. (description from website)
CDC, Division of Healthcare Quality Promotion
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, U.S.A
Tel: (404)639-3311
Public Inquiries: (404) 639-3534 / (800) 311-3435
Antimocrobial-resistant pathogen, No. units, No. tested, Pooled mean, Percentile
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/ncidod/hip/SURVEILL/NNIS.HTM
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
National Notifiable Diseases Surveillance System
130
The CDC have designated 60 infectious diseases as "national notifiable diseases." State
and local authorities report incidences of these diseases to CDC, which compiles
surveillance data in its MMWR. Data from 1996 to the present.
CDC
John W. Ward, M.D., Editor
Epidemiology Program Office MS C-08
Centers for Disease Control and Prevention
1600 Clifton Rd.
Atlanta, GA 30333
Fax:(404)639-4198
E-mail: mmwrq@cdc.gov
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.cdc.qov/mmwr/distrnds.html
Data Source Name
National Notifiable Diseases Surveillance System (Australia)
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
131
The Communicable Diseases Network Australia collects data from departmental health
authorities on the occurrence of 61 infectious diseases. Annual, monthly, and outbreak data
are reported. Several diseases listed in this system may be transmitted via water, including:
Cryptosporidiosis, Hepatitis A and E, Legionellosis, Salmonellosis, and Shigellosis.
Australian Department of Health and Aging; The Communicable Diseases Network Australia
GPO Box 9848
Canberra ACT 2601, Australia
cdi.editor@health.gov.au
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.cda.gov.au/surveil/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Occupational Exposure Survey (NOES)
146
NOES was a nationwide observational survey conducted between 1981 and 1983 on a
sample of nearly 5,000 establishments, a selection designed to represent those segments of
American industry covered under the Occupational Safety and Health Act of 1970.
CDC National Institute for Occupational Safety and Health (NIOSH)
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH (1-800-356-4674)
Fax: 1-513-533-8573
CAS RN, Name, Standard industrial classification (SIC) code, Number of workers exposed
to the substance, Number of facilities handling the material
This source is considered relevant for the CCL Universe because it contains information that
is related to potential exposure.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, however some tabular data have been obtained from ERG.
http://www.cdc.gov/niosh/pdfs/89-103-b.pdf
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Data Source Name
Identification Number
National Pesticide Information Retrieval System
261
Data Source Description
The National Pesticide Information Retrieval System (NPIRS®) is a collection of pesticide-
related databases available by subscription. NPIRS® is under the administration of the
Center for Environmental and Regulatory Information Systems, CERIS, at Purdue
University in West Lafayette, Indiana.
There are five (5) databases and three (3) dictionaries (vocabularies) available for searching.
Databases:
Federal and State Pesticide Product
Pesticide Document Management System (PDMS)
Data Submitters List
Tolerance Index
Federal Register Archive
Dictionaries:
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Chemical - active ingredient accepted label names, chemical synonyms, CAS
Registry Numbers, EPA chemical codes, brand and trade names
Site - site names, methods and times of application, site codes
Pest - common pest names, life cycles, pest codes
Over 400 individuals access NPIRS® for information pertaining to product registration.
Many individuals use NPIRS® to assist in registering pesticides and developing market
strategies based on currently registered products or pending registrations, (description from
website)
CERIS, Purdue University
CERIS/NPIRS®
1231 Cumberland Avenue, Suite A
West Lafayette IN 47906-1317 Office: 765-494-6616
FAX: 765-494-9727
WEB Info Site: http://ceris.purdue.edu/npirs
Chemical, Site, Pest, Federal brand names, EPA registration number, Product status,
Registrant name and address, Product formulation, Federal restricted use status, Use type
classifications, Active ingredients, Registration action dates, Sites on which to use product,
Pests controlled, Site/pest combinations, Special Local Need registrations (SLNs), State
brand names, State registration numbers, Year of last registration, Document title and
author, Submitters (first/all), Research subjects, CFR part and paragraph, Parts per million
levels, FR dates, Full text of articles, Article dates, Citations, Departments/agencies, CFR
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with the Pesticide Data Submitters' List, the Pesticide Product
Information Database, and the Pesticide Tolerance Index.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ceris.purdue.edu/npirs/index.html
Data Source Name
Identification Number
Data Source Description
National Pesticide Use Database
128
The National Pesticide Use Database was created by the National Center for Food and
Agricultural Policy (NCFAP) in conjunction with the United States Department of Agriculture.
The National Pesticide Use Database compiles state and crop pesticide use data from
publicly available reports and from surveys conducted by the National Agricultural Statistics
Service. First-issued in 1995, the NCFAP pesticide use database is widely used by
governmental agencies, environmental groups and private industry. In November 2000,
NCFAP released an updated version of the national database which delineates the use of
220 active ingredients on 87 crops in the 48 contiguous states in 1997.
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Note: Although 1992 and 1997 are benchmark years for the database, the data for these
years are derived from use estimates made between 1990 to 1993 and 1994 to 1998,
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
respectively. The NCFAP databases are more accurately described as circa 1992 and circa
1997.
Users are advised to read the report Pesticide Use in U.S. Crop Production: 1997, that
describes how the database was compiled and identifies the references that were used as
the source for each record in the database. A detailed description of the internet files is also
included in this report, (description from website)
National Center for Food and Agricultural Policy (NCFAP)
National Center for Food and Agricultural Policy
1616 P Street NW, First Floor
Washington, DC 20036
Phone: 202-328-5048
ncfap@ncfap.org
Nathan Reigner
Phone: (202) 328-5005
Email: reigner@ncfap.org
Name, Ibs Al applied, # States applied
This source is considered relevant for the CCL Universe because it contains information on
pesticide use, an indicator of potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.ncfap.org/database/default.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
National Reconnaissance of Emerging Contaminants (NREC) -
USGS Toxic Substances Hydrology Program
132
This database is currently in compilation and will include occurrence data collected by the
USGS Toxic Substances Hydrology Program from 1999 to 2001 in samples from 142
streams, 55 wells, and seven effluent samples from 36 states. The majority of the sites
sampled were expected to be susceptible to emerging contaminants through the pathway of
either animal or human wastewater. A smaller subset of the sites were located in settings
where occurrence of emerging contaminants was predicted to be unlikely. A total of 94
target chemicals were measured, including 22 human and veterinary antibiotics, 13
prescription drugs, five nonprescription drugs, 39 industrial and household wastewater
products (e.g., caffeine and personal care products), and 15 reproductive and steroidal
hormones. This review refers to the USGS Open File Report (02-94) available on the USGS
website. This online report includes all the raw data from the stream sampling portion of the
study.
USGS
District Chief U.S. Geological Survey
P.O. Box 1230
Iowa City, Iowa 52244
Ambient Water Occurrence Concentrations, Min, Max Value
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
Retrievability Explanation
This source meets retrievability criteria because USGS provided the data directly to EPA in a
useable format.
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Source URL
http://toxics.usas.gov/reaional/emc.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
National Research Council (NRC) Publications
147
The National Research Council is part of the National Academies, which also comprise the
National Academy of Sciences, National Academy of Engineering and Institute of Medicine.
They are private, nonprofit institutions that provide science, technology and health policy
advice under a congressional charter. The Research Council was organized by the National
Academy of Sciences in 1916 to associate the broad community of science and technology
with the Academy's purposes of further knowledge and advising the federal government.
Functioning in accordance with general policies determined by the Academy, the National
Research Council has become the principal operating agency of both the National Academy
of Sciences and the National Academy of Engineering in providing services to the
government, the public and the scientific and engineering communities. The Research
Council is administered jointly by both Academies and the Institute of Medicine through the
National Research Council Governing Board. The chairman of the National Research Council
is Bruce Alberts, (description from website)
National Research Council, National Academies Press
National Academies Press
500 Fifth Street, NW
Lockbox 285
Washington, DC 20055
Phone: 888-624-8373 or 202-334-3313
email: zjones@nas.edu
Fax: Customer Service/General (202) 334-2451
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nap.edu/
Data Source Name
Identification Number
Data Source Description
Proprietor
National Sanitary Foundation (NSF) - Additives Standards 60 and 61
148
NSF 60, Drinking Water Treatment Chemicals - Health Effects is the nationally recognized
health effects standard for chemicals which are used to treat drinking water. NSF 61,
Drinking Water System Components - Health Effects is the nationally recognized health
effects standard for all devices, components and materials which contact drinking water.
(description from website)
National Sanitary Foundation
Contact Information
Relevance Explanation
Completeness Explanation
777 East Eisenhower Parkway
Ann Arbor, Ml 48108
Email: service@techstreet.com
Phone: (800) 699-9277
Fax:(734)913-3946
This source is considered relevant for the CCL Universe because it contains information on
health effects standards for drinking water.
It meets considerations because it is peer reviewed.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.techstreet.com/cgi-bin/detail7product id=1155045
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Sediment Inventory (NSI)
149
The NSI is a database that documents the composition of sediment in rivers, lakes, oceans,
and estuaries. It also incorporates an assessment of potential human and environmental
health effects of the contaminants in the sediment. Data sources for the study included
sediment chemistry data, chemical residue level data in edible tissue of aquatic organisms,
and sediment toxicity studies, which were collectively assembled from more than 21,000
sampling stations nationwide. This database is of potential interest because sediments can
contribute contaminants to drinking water, (description from website)
EPA Office of Water, OST
U.S. Environmental Protection Agency
Office of Water
Office of Science and Technology (4301T)
1200 Pennsylvania Avenue, N.W.
Washington, D.C. 20460
Analyte sampled, Mean, Max, Median, Min, Measured/estimated value, Fraction organic
carbon, Nondetect flag, Number of samples, Units
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in sediments (which can contribute contaminants to drinking water), and can
indicate potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.aov/OST/BASINS/metadata/nsi.htm
Data Source Name
Identification Number
Data Source Description
National Stream Quality Accounting Network (NASQAN)
133
According to the web site, the primary goals of the NASQAN are to "characterize large sub-
basins of rivers, to determine regional source areas for chemical contaminants, and to
assess the effects of human influences on observed concentrations and amounts of the
chemicals." Since 1995, NASQAN has focused on monitoring the concentration of a broad
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
range of chemicals including pesticides, major ions, and trace elements in four of the
nation's largest river systems: the Mississippi, the Columbia, the Colorado, and the Rio
Grande. NASQAN contains data relevant to contaminant screening, such as occurrence of
major ions, trace elements, and dissolved pesticides. Most of the data are easily exportable
in tabular form.
USGS
Office of Water Quality
U.S. Geological Survey
412 National Center
Reston, Virginia 20192
Internet: http://water.usgs.gov/nasqan
Occurrence concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is redundant with NAWQA.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://water.usas.aov/nasaan/progdocs/wri014255/index.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
National Toxicology Program (NTP) Health and Safety Profiles
150
The NTP has developed around 500 "Toxicity and Carcinogenicity" reports and 66 "Toxicity"
reports for organic and inorganic chemicals. These reports summarize toxicological data and
includes some carcinogenicity and toxicity endpoints and categorizations. Another important
feature of the "Toxicity and Carcinogenicity" reports is a strength of evidence categorization
for the conclusions drawn in the studies.
Agents may be nominated to the NTP for study by any person or group regardless of
affiliation. The nominations go through a rigorous internal and external scientific review to
determine the need for testing and a check with Government Agencies to see if the use of
an agent falls under any Federal Regulations. Once an agent has been selected by the NTP
Executive Committee for study, a staff scientist is assigned to develop appropriate study
protocols to obtain the needed toxicity data. Using these protocols, the toxicity studies are
conducted at contract laboratories under a standard set of operational guidelines. Each
laboratory is required to have a health and safety plan in place for each chemical to protect
their workers.
Between 1978 and 1991 a contractor assembled health and safety background information
for chemicals selected for study by the Program. These documents were provided to the
laboratories at the time they conducted the agent studies to help them develop the individual
health and safety plans. It is this set of files that we have on our web site. Currently, the
responsibility for assembling this health and safety information is that of the testing
laboratory, (description from website)
National Toxicology Program; NIH
NTP Liaison and Scientific Review Office
P.O. Box12233, MDA3-01
Research Triangle Park, NC 27709
Telephone: (919)541-0530
E-mail: liaison@starbase.niehs.nih.gov
ntpwm@niehs.nih.gov
BP, Carcinogenicity, Critical effects, Dose, Duration, GenTox, GMM Abstract, GMM Care,
GMM GenTox, GMM Neo, GMM Nonneo, Hazard class, MP, Mutation Data, Other toxicity
data, Path, RACE Abstract, Rationale for testing, RDGT Abstract, Reactivity, Route, SAX
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
toxicity evaluation, Species, Stability, Statistical analysis, Strain and Species, Study Result,
Study Type, Subsidiary Risk, Survival, Growth weights and Gross observations,
Teratogenicity, Tissue, Tox Abstracts, TOX Growth Surv, Toxicity, Toxicokinetic, TR Care
act, TR Gen Tox, TR Neo, TR Nonneo, TR Path Surv Growth, TR Target Org, Use, Vapor
Density, Vapor Pressure, Water Solubility
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ntp-server.NIEHS.nih.gov/
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
National Toxicology Program (NTP) Studies
248
The NTP has developed around 500 "Toxicity and Carcinogenicity" reports and 66 "Toxicity"
reports for organic and inorganic chemicals. These reports summarize toxicological data and
includes some carcinogenicity and toxicity endpoints and categorizations. Another important
feature of the "Toxicity and Carcinogenicity" reports is a strength of evidence categorization
for the conclusions drawn in the studies.
Agents may be nominated to the NTP for study by any person or group regardless of
affiliation. The nominations go through a rigorous internal and external scientific review to
determine the need for testing and a check with Government Agencies to see if the use of
an agent falls under any Federal Regulations. Once an agent has been selected by the NTP
Executive Committee for study, a staff scientist is assigned to develop appropriate study
protocols to obtain the needed toxicity data. Using these protocols, the toxicity studies are
conducted at contract laboratories under a standard set of operational guidelines. Each
laboratory is required to have a health and safety plan in place for each chemical to protect
their workers.
Between 1978 and 1991 a contractor assembled health and safety background information
for chemicals selected for study by the Program. These documents were provided to the
laboratories at the time they conducted the agent studies to help them develop the individual
health and safety plans. It is this set of files that we have on our web site. Currently, the
responsibility for assembling this health and safety information is that of the testing
laboratory, (description from website)
National Toxicology Program; NIH
NTP Liaison and Scientific Review Office
P.O. Box12233, MDA3-01
Research Triangle Park, NC 27709
Telephone: (919)541-0530
E-mail: liaison@starbase.niehs.nih.gov
ntpwm@niehs.nih.gov
Name, Synonyms, CASRN, Formula, Structure, Categories of evidence of carcinogenic
activity, Statistical results
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval. NTP studies provide unique and exceptional data and are included to
supplement the CCL Universe.
Source URL
http://ntp-server.NIEHS.nih.gov/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
National Water Information System (NWIS Web)
151
As part of its program of disseminating water data to the public, the USGS maintains a
distributed network of computers and file-servers for the storage and retrieval of water data
collected through its activities at approximately 1.5 million sites around the country. This
system is called the National Water Information System (NWIS). Many types of data are
stored in this NWIS network, including: site information, time-series (flow, stage,
precipitation, chemical), peak flow, ground water, and water quality. NWIS data comes from
all 50 states, selected territories, and border stations, from 1896 to the present, (description
from website)
USGS
Questions about data h2oteam@usgs.gov
Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is redundant with NAWQA.
This source meets retrievability criteria because it is in tabular format.
http://waterdata.usas.gov/nwis
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
National Water Quality Assessment (NAWQA)
134
The NAWQA database, maintained by USGS, describes the status and trends in the quality
of the nation's groundwater and surface water resources.
The U.S. Geological Survey (USGS) began its NAWQA (National Water Quality Assessment)
program in 1991, systematically collecting chemical, biological, and physical water quality
data from 42 study units (basins) across the nation. The data warehouse currently contains
and links the following data up through 9/30/2002:
Chemical concentrations in water, bed sediment, and aquatic organism tissues for about 609
chemical constituents
Site, basin, well and network characteristics with many descriptive variables
Daily stream flow information for fixed sampling sites
Ground water levels for sampled wells
6,400 surface water sites and 7,000 wells
44,000 nutrient samples and 26,000 pesticide samples as well as 8,000 VOC samples
2,650 samples of bed sediment and aquatic organism tissues
This database may be useful for examining nationally representative pesticide and VOC
occurrence in ambient water and drinking water sources; however, the composition and
presentation of the data vary widely from region to region. NAWQA provides high-quality,
nationally representative data reviewed by the National Academy of Sciences (NAS).
(description from website)
USGS
NAWQA Headquarters
Phone: 1-703-648-5716
E-mail: nawqa_whq@usgs.gov
Maintainer: James Ulrich
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
E-mail: julrich@usgs.gov
Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because USGS provided the data directly to EPA in a
useable format.
http://water.usas.gov/nawaa/
Data Source Name
Identification Number
Data Source Description
NIOSHTIC
279
NIOSHTIC® is a bibliographic database of literature in the field of occupational safety and
health. About 160 core, English language technical journals provide approximately 35 percent
of the additions to NIOSHTIC® annually. Over 4,000 other sources of technical articles and
reports.
Because NIOSH examines all aspects of adverse effects experienced by workers, much of
the information contained in NIOSHTIC® has been selected from sources that do not have a
primary occupational safety and health orientation.
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The CIS subset of NIOSHTIC® records are required to provide a CAS Registry Number and
discuss one or more of the following subjects: Hazmat, Biodegradation, Environmental Fate,
Gastrointestinal Absorption, Toxicity, Carcinogenicity, Turmorigenicity, Mutagenicity,
Teratogenicity, Acid Dissociation, Irritation Data, Occupational Concentrations,
Bioconcentration Factor, Effluent Concentrations, Photooxidation, Ultraviolet Absorption,
Volatilization, Superfund Sites, or Occupational Safety.
SUBJECT COVE RAGE:
Proprietor
Contact Information
Type of Data Elements
behavioral sciences
biochemistry, physiology and metabolism
biological hazards
chemistry
control technology
education and training
epidemiological studies of disease/disorders
ergonomics
hazardous waste
health physics
occupational medicine
pathology and histology
safety
toxicology
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.nisc.com/cis/details/nioshtic.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Office International des Epizooties (OIE) Handistatus II
155
The current prototype for Handistatus II (i.e Help with World Animal Disease Status - version
2) is a Web application containing information on animal diseases that have serious
consequences for international trade or public health. This information is regularly updated
based on the emergency, monthly and annual reports sent to the Central Bureau of the
Office International des Epizooties (OIE) by the veterinary administrations of countries and
other official sources.
The annual information on the animal health situation worldwide is almost entirely derived
from the collection and processing of the questionnaires on animal health, common to the
Food and Agriculture Organization of the United Nations (FAO), the World Health
Organization (WHO) and the OIE, which the OIE has distributed to all countries on behalf of
the three organisations since 1996. (description from website)
Office International des Epizooties
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Unknown
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It does not meet considerations because no contact information or information on type of
data elements is available.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.oie.int/hs2/report.asp?lang=en
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Office Internationales Epizooties
244
Animal and human health statistics (AWWA)
DIE
Unknown
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It does not meet considerations because no contact information or information on type of
data elements is available.
This source is identical to Office International des Epizooties (DIE) Handistatus II (source
155).
This source meets retrievability criteria because it is in tabular format.
http://www.oie.int/hs2/report.asp?lang=en
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Office of Pollution Prevention and Toxics (OPPT) Chemical Fact
Sheets
156
OPPT Chemical Fact Sheets provide a brief summary of information on selected TRI
chemicals. Each of the approximately 30 Fact Sheets covers each chemical's identity,
production and use, environmental fate, and health and environmental effects. Each also
includes a list of laws under which the chemical is regulated, phone numbers, and the names
of EPA offices and other agencies one can call or contact for more information.
EPA Office of Pollution Prevention and Toxics
US EPA
Office of Pollution Prevention & Toxics
1200 Pennsylvania Avenue, NW
Mail Code 7401-M
Washington, DC 20460
Phone:(202)564-3810
Email: oppt.homepage@epa.gov
What is the contaminant, how is it used, and how might I be exposed? What happens to the
contaminant in the environment? How does the contaminant affect human health and the
environment? What EPA program offices regulate the contaminant, and under what laws is it
regulated? What other federal agencies or groups can I contact for information on the
contaminant?
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/opptintr/chemfact/
Data Source Name
Identification Number
Data Source Description
Oil and Hazardous Materials/Technical Assistance Data System
287
This database includes 1,402 MSDS-like fact sheets prepared by the US Environmental
Protection Agency in the 1970s and 1980s. Each fact sheet deals with one chemical
substance. The database is no longer updated, and some material in the database has been
rendered incorrect overtime by changes in regulatory requirements. However, the database
still contains a wealth of still-useful data and references. Consequently, each record is
presented with a warning about the age of the database and the need to verify critical
information through more current sources. Users can retrieve records by CAS Registry
Number (the preferred method), chemical name, and/or subject terms/phrases.
SUBJECT COVERAGE:
* CAS Registry Numbers * General Toxicology
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
* Chemical Identification * Hazards
* Chemical/Physical Properties * Human Contact and Exposure
* Detection * Reactivity
* Emergency Response * Plant Toxicology
* Environmental Fate * Response and Disposal
* Environmental Chemistry * Transportation and Storage
* Fire Protection and Explosion
(description from website)
National Information Services Corporation (NISC)/EPA
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
CAS RN, General Toxicology, Hazards, Chemical/Physical Properties, Human Contact and
Exposure, Detection, Reactivity, Emergency Response, Plant Toxicology, Environmental
This source is considered relevant for the CCL Universe because it contains environmental
fate data, that may be used as an indicator of potential occurrence.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/ohm-tads.htm
Data Source Name
Identification Number
Data Source Description
Oncologic
237
The Cancer Expert System is a personal computer software program developed under a
cooperative agreement between EPA's Office of Pollution Prevention and Toxics (OPPT) and
LogiChem, Inc. The IBM-compatible DOS (non-Windows) program is registered under the
trademark OncoLogic®. The Cancer Expert System or OncoLogic® can analyze a chemical
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Proprietor
Contact Information
structure to determine the likelihood that it may cause cancer. This is done by applying the
rules of structure activity relationship (SAR) analysis and incorporating knowledge of how
chemicals cause cancer in animals and humans.
The Cancer Expert System is comprised of four subsystems that evaluate fibers, metals,
polymers, and organic chemicals of diverse chemical structures. The program applies SAR
analysis to predict the potential cancer-causing effects of a chemical. In addition to SAR
analysis, the Cancer Expert System applies the knowledge gained from studies of how
chemicals cause cancer in animals and humans, (description from website)
Logichem
Logichem, Inc.
P.O. Box 357
Boyertown, PA 19512
Telephone: 717-420-9417
Telefax: 717-420-9419
E-mail: webinfo@logichem.com
Internet: http://www.logichem.com
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Rating of carcinogenicity potential, Scientific rationale for rating
This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a
http://www.epa.qov/opptintr/cahp/actlocal/can.html
Data Source Name
Identification Number
Data Source Description
Organisation for Economic Co-operation and Development (OECD)
Integrated HPV Database
152
This database tracks all High Production Volume (HPV) chemicals through the process of
investigation in the OECD Programme on the Investigation of Existing Chemicals). It allows
Member countries and industry to select chemicals for sponsorship and shows the stage of
investigation of any particular chemical at any given time. Finally, once agreed in the
OECD, it shows the results of assessments as well as the actual reports and background
information behind them.
The database contains the list of HPV chemicals together with any annotations on each
chemical provided to the Secretariat by Member countries. Each chemical is identified as to
exactly which stage it is at in the assessment process, and for those chemicals which have
already been selected for sponsoring (i.e. SIDS chemicals), there are links to relevant
documents.
When making the first evaluation of an existing chemical, a minimum set of data is
necessary to determine its potential hazards. To ensure that such data are available, OECD
developed the SIDS (Screening Information Data Set). The SIDS outlines the minimum data
elements essential for determining whether or not a chemical requires further investigation.
When data gaps for a specific chemical are identified, testing is carried out by the chemical
industry.
The database operates at three levels (Secretariat, Member country and general public) with
control of significant data input (such as confirmation of sponsorship) being at the
Secretariat level. Once a chemical has been sponsored by a Member country, that country
inputs specific information on the investigation of the chemical.
The database has a comprehensive search facility allowing searches to be made in a number
of categories: e.g., chemical name, CAS number, sponsoring country, stage of
investigation. Those chemicals which have not yet been selected for sponsorship can be
readily identified thus facilitating future sponsorship by both Member countries and industry.
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Members of the general public have "read only" access to the database and so can follow
the progress of a chemical both through and after its assessment. They can also obtain
completed assessments on individual chemicals once these have been agreed in the OECD.
Proprietor
Contact Information
Type of Data Elements
Organisation for Economic Co-operation and Development
Mr. Oscar Hernandez
Risk Assessment Division, Office of Prevention, Pesticides & Toxics
US-EPA (7403)
ICC Building, 1200 Pennsylvania Avenue, N.W.
20460 Washington D.C.
United States
Tel: (1-202) 564-0930 Fax: (1-202) 564-7450
E-mail: hernandez.oscar@epa.gov
Name, CASRN, SIDS status
Relevance Explanation
NstofHPV
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
(description from website) This source is considered relevant for the CCL Universe because it is a
chemicals, which may indicate possible occurrence. It also contains data elements from
toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://cs3-ha.oecd.org/scripts/hpv/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
OSHA 1988 Permissible Exposure Limits (PELs)
234
Record of OSHA regulatory decisions (AVWVA)
NIOSH
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH (1-800-356-4674)
Fax: 1-513-533-8573
Name, CASRN, OSHA PEL
This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.osha.gov/SLTC/pel/
Data Source Name
Identification Number
Data Source Description
Palm Top Emergency Action for Chemicals (PEAC-CW System)
Federal Technical Support Working Group
163
The Technical Support Working Group, a Federal Interagency group focusing on developing
new technology for combating Terrorism has sponsored the upgrade of the commercially
available Palmtop Emergency Action for Chemicals (PEAC) system. The PEAC-CW lists
over 10,000 toxic chemicals and includes 6 chemical warfare agents and 73 precursor
chemicals, This capability was designed for use by Federal emergency and law enforcement
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officers, and all State and Local Fire, Law Enforcement, HAZMAT, Bomb Squad, and other
emergency/public government services organizations who may be involved with responding
to terrorists, HAZMAT incidents, or other chemical spill emergencies.
The PEAC-CW system contains information from a number of sources, including NIOSH,
NFPA, AIHA, MSDS, and DOT for over 10,000 chemicals and synonyms searchable by its
chemical name or UN number including:
Proprietary dispersion model that develops site specific Protective Action Distances based
on input for meteorology, surrounding terrain, container size and orientation, type of release
and chemical exposure guideline. Or display DOT ERG2000 values (green pages).
Chemical and Physical properties such as flash point, boiling point, LEL, UEL, auto ignition
temp, melting point, vapor pressure, vapor density, published toxicity levels, etc.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Specific Chemical Protective Clothing information from manufacturers
NFPA hazard Identification system (NFPA 704 - Standard System for the Identification of
Fire Hazards of Materials)
NIOSH Guidebook respirator recommendations
Synonyms list
Access to procedures and recommendations for 62 chemical classes from DOT ERG-2000
Guide information (orange pages)
(description from website)
Technical Support Working Group
Aristatek, Inc. of Laramie, Wyoming developed the PEAC-CW system. The PEAC-CW
system is available directly from Aristatek or its distributors by calling toll-free 1-877-912-
2200 or fax 307-721-2337. Software can be purchased separately without a platform or
preloaded on a platform (prices vary depending on platform selected) and quantity discounts
are available. Detailed information is available online at http://www.aristatek.com.
"Published toxicity levels"
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.tswa.aov/tswg/cbrnc/PEACPress.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Pan American Health Organization (PAHO) Communicable Disease
158
Pan American Health Organization (PAHO) has provided an index of data sources and
publications relevant to major communicable diseases in the Americas. It provides links to
surveillance data from PAHO countries.
Pan American Health Organization
Dr. Mirta Roses Periago, Director
Pan American Health Organization
Pan American Sanitary Bureau
Regional Office of the World Health Organization
525 Twenty-third Street, N.W.
Washington, D.C. 20037
United States of America
Country/City Code: (202)
Tel: 974-3000
Fax: 974-3663
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
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Completeness Explanation
Redundancy Explanation
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.paho.org/Selection.asp?SEL=TP&LNG=ENG&CD=BDISPRVCT
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Permit Compliance System (PCS) Database
161
The Permit Compliance System (PCS) provides information on companies which have been
issued permits to discharge waste water into rivers. You can review information on when a
permit was issued and expires, how much the company is permitted to discharge, and the
actual monitoring data showing what the company has discharged. The Water Discharge
Permits Query allows you to retrieve preselected data from the PCS database in
Envirofacts. You can narrow your search by selecting various options including facility
name, geographic location, standard industrial classification, and chemicals. You may also
use the PCS Customized Query to retrieve data and design a query for your particular
needs, using any data element available from the Envirofacts Warehouse. Customized
Queries are primarily geared toward more experienced users. There is also information on
related laws and regulations, (description from website)
EPA OECA
Users can contact EPA using email form located at:
http://www.epa.gov/enviro/html/pcs/pcs_feedback.html
Facility, Address, Activity Status, Permit Type, Issued Date, Expired Date, USGS Hydro
Basin, Stream Segment, Flow, Receiving Stream Class, Federal_grant_ind, Receiving
Waters, Final Limits Ind Pretreatment Code, Sludge Information, Permit Documents,
Inspections, Outfalls/pipe Schedules, Limits Report, Measurements and Violations,
Compliance Schedules and Violations, Evidentiary Hearings, Pretreatment
This source is considered relevant for the CCL Universe because it contains information on
discharge of waste to rivers, which may indicate potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/enviro/html/pcs/index.html
Data Source Name
Identification Number
Data Source Description
Persistent, Bioaccumulative, and Toxic Profiles (PBT Profiler)
160
The PBT Profiler was designed to be an easy to use, widely available, no-cost tool to screen
chemicals lacking experimental data in order to help identify pollution prevention (P2)
opportunities. It is a continuation of the Office of Pollution Prevention and Toxics (OPPT,
U.S. Environmental Protection Agency) Pollution Prevention (P2) Assessment Framework - a
collection of screening models and methods to help promote the design, development, and
application of safer chemicals and processes. The P2 Framework uses computerized
methods, such as structure/activity relationships (SARs) and standard scenarios, to predict
risk related data (physical/chemical properties, bioconcentration, environmental fate,
carcinogenicity, toxicity to aquatic organisms, worker and general population exposure, and
other information) on chemicals lacking experimental data. The PBT Profiler arose from
experience gained in the P2 Framework's outreach program, a vigorous set of initiatives by
collaborators in the business, government, and academic sectors to promote the voluntary
use of these tools to reduce pollution and highlight the potential economic benefits of
informed environmental decision making.
The PBT Profiler uses a subset of P2 Assessment Framework computer-based tools to help
identify chemicals that potentially may persist, bioaccumulate, and be toxic to aquatic life,
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Contact Information
i.e., PBT chemicals. The release of even small amounts of persistent, bioaccumulative, and
toxic chemicals to the environment is of concern because they can accumulate over time to
higher concentrations and, therefore, have a higher potential to adversely impact human
health and the environment. The overwhelming majority of known chemical substances do
not have experimental persistence, bioaccumulation, and toxicity data available. Only a
small fraction of chemicals currently in commerce, including the 2,000 new chemicals
introduced each year, have sufficient data available to perform a thorough evaluation of
potential risks. The PBT Profiler was designed to help interested parties voluntarily screen
chemicals for persistence, bioaccumulation, and aquatic toxicity characteristics when no
experimental data are available, (description from website)
EPA (OPPT), Environmental Science Center, Syracuse Research Corporation
Jay L. Tunkel, Ph.D.
Project Manager
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Predicted persistence (half life) in air, water, soil, and sediment, Bioaccumulation (BCF), Fish
ChV, Includes structural information
This source is considered relevant for the CCL Universe because it could be a source of
information on persistence, providing an indicator of occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates.
http://www.pbtprofiler.net/default.asp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Pesticide Action Network (PAN) Pesticide Database
159
The PAN Pesticide Database brings together a diverse array of information on pesticides
from many different sources, providing human toxicity (chronic and acute), ecotoxicity and
regulatory information for about 6,400 pesticide active ingredients and their transformation
products, as well as adjuvants and solvents used in pesticide products.
This database of active ingredients has been integrated with information in the U.S. EPA
product databases, which provide information on formulated products (the form of the
pesticide that growers and consumers purchase for use) containing the active ingredients.
The information is most complete for pesticides registered for use in the United States.
(description from website)
Pesticide Action Network
Pesticide Action Network North America
49 Powell St., Suite 500
San Francisco, CA 94102
USA
Phone:(415)981-1771
Fax: (415)981-1991
Email addresses:
panna@panna.org (general comments)
net-admin@panna.org (comments on our online work)
Chemical Name, CAS Number, U.S. EPA PC Code, CA DPR Chem Code, Molecular Weight,
Use Type, Chem Class, Route of Exposure, Symptoms, First Aid, PAN Bad Actor
Relevance Explanation
Completeness Explanation
Chemical, Acute Toxicity, Carcinogen, Cholinesterase Inhibitor, Ground Water Contaminant,
Developmental or Reproductive Toxin, Endocrine Disrupter
This source is considered relevant for the CCL Universe because it contains health effects
data.
It meets considerations because it meets all NDWAC minimum data requirements.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.pesticideinfo.org/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Pesticide Data Program
265
The Pesticide Data Program (POP) is a national pesticide residue database program.
Through cooperation with State agriculture departments and other Federal agencies, POP
manages the collection, analysis, data entry, and reporting of pesticide residues on
agricultural commodities, with an emphasis on those commodities highly consumed by
infants and children, (description from website)
USDA
POP Staff:
Agricultural Marketing Service
Science & Technology, Monitoring Programs Office
8609 Sudley Road, Suite 206
Manassas, VA20110
Director: Martha Lament
Phone: (703) 330-2300 ext. 17 Fax: (703) 369-0678
Deputy Director: Diana Haynes
Phone: (703) 330-2300 ext. 34 Fax: (703) 369-0678
Total Samples Analyzed, Samples with Residues Detected, Percent of Samples with
Detections, Different Pesticides Detected, Different Residues Detected, Total Residue
Detections, % of Samples with Detects, Minimum Value Detected,ppm, Maximum Value
Detected,ppm, Number of Detections of Pesticides in Drinking Water, Pesticides Detected
Above Limit of Quantification in Drinking Water
This source is considered relevant for the CCL Universe because it contains measurements
of pesticide residues, an indicator of potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.ams.usda.gov/science/pdp/index.htm
Data Source Name
Identification Number
Data Source Description
Pesticide Data Sheets (PDS) - WHO, FAO
162
Pesticide Data Sheets (PDSs) contain basic information for safe use of pesticides. The
Pesticide Data Sheets are prepared by WHO in collaboration with FAO and give basic
toxicological information on individual pesticides. Priority for issue of PDSs is given to
substances having a wide use in public health programmes and/or in agriculture, or having a
high or an unusual toxicity record. The data sheets are prepared by scientific experts and
peer reviewed. The comments of industry are provided through the industrial association,
Proprietor
Contact Information
Type of Data Elements
GIFAP. The data sheets are revised from time to time as required, (description from
website)
World Health Organization, Food and Agriculture Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Absorption route, Additional Regulations Recommended, Agriculture, Horticulture and
Forestry, Carcinogenicity, Decontamination Of Spillage And Containers, Dietary studies,
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Redundancy Explanation
Retrievability Explanation
Source URL
Disposal And/Or Decontamination Of Containers, Emergency Aid, Entry Of Persons Into
Treated Areas, Excretion products, Handling, Household Use, Labelling, Laboratory Methods,
Medical Diagnosis and Treatment in Cases of Poisoning, Mode of action, Precautions in
Use, Public Health Programmes, Recommended Restrictions on Availability, Residues in
Food and Water, Selected Properties, Selection, Training and Medical Supervision of
Workers, Surveillance Tests, Susceptible pests, Toxicity - Non-Mammalian Species,
Toxicity, Repeated Dose, Toxicity, Single Dose, Toxicology - Mammals, Toxicology - Man,
Transportation and Storage, Unintended Effects, Use Pattern
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
This source is redundant, as it is wholly available as part of INTOX (source 105).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/pds.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Pesticide Data Submitters List (PDSL)
266
The Pesticide Data Submitters List is a compilation of names and addresses of registrants
who wish to be notified and offered compensation for use of their data. It was developed to
assist pesticide applicants in fulfilling their obligation as required by sections 3(c)(1)(f) and
3(c)(2)(D) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and 40 CFR
Part 152 sub part E regarding ownership of data used to support registration.
All pesticides sold or distributed in the United States must be registered by EPA, based on
scientific studies showing that they can be used without posing unreasonable risks to people
or the environment. When applying for registration of a pesticide product, a registrant may
develop and submit the required data, cite all previously submitted data, or cite selected
data. When an applicant cites data previously submitted by another pesticide registrant, the
applicant must make a valid offer to pay compensation to the owner of that data. The Data
Submitters List contains the names and addresses of companies who submitted data relating
to certain pesticide chemicals who wish to receive such offers, (description from website)
EPA, Office of Pesticide Programs
John Jamula
jamula.john@epa.gov
Information Resources and Services Division
Office of Pesticide Programs (7504C)
Environmental Protection Agency
401 M Street SW
Washington, DC 20460
Ph: 703-305-6426
Fax: 703-305-7670
Chemical Name, Company #, Data Types
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with NPIRS (source 261); however, NPIRS is a subscription source.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.qov/opppmsd1/DataSubmittersList/
Data Source Name
Identification Number
Data Source Description
Pesticide Ecotoxicity Database
257
Over the last 30 years, pesticide registrants or manufacturers have submitted thousands of
ecotoxicity studies to support the registration or approval of their pesticide products.
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Ecotoxicity studies measure the effects of chemicals on fish, wildlife, plants, and other wild
organisms.
EPA has reviewed these studies according to criteria outlined in their Standard Evaluation
Procedures Manuals and testing methods accepted by the scientific community. After
reviewing these studies, EPA scientists have determined if they are acceptable for use in
the regulatory process.
In 1991, EPA began electronically summarizing acceptable studies and has now entered over
15,000 summary records for about 680 pesticide active ingredients into a computerized
database called the Pesticide Ecotoxicity Database.
These summary records include endpoints measurements such as the LD50 (the amount or
dose of a chemical which kills 50% of the exposed animals) and the NOEL or No Observed
Effect Level (the highest concentration of a chemical in a toxicity test that has no
significant adverse effect on the exposed population of test animals).
Although most of the toxicity information in this database was compiled from actual studies
conducted by commercial laboratories, the database also contains acceptable studies
conducted by EPA, USDA, and the Fish and Wildlife Service laboratories and published data
which meets the Agency's guideline testing requirements.
The Pesticide Ecotoxicity Database is written in DBase III+ and contains 32 fields per record
entry. Each record entry summarizes one ecotoxicity study for one species whether it is in a
single species study or a multiple species study, (description from website)
EPA
Brian Montague at Montague.Brian@epa.gov or call 703-305-6438
LD50, NOEL
This source does not meet relevance criteria because it contains only information on
ecological toxicity.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name
Identification Number
Pesticide Handler Exposure Database
262
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The Pesticide Handler Exposure Database (PHED) is a database containing voluntarily
submitted empirical exposure data for workers involved in the handling or application of
pesticides in the field; it currently contains data for over 2000 monitored exposure events.
The basic assumption underlying the system is that exposure to pesticide handlers can be
calculated generically, based on the available empirical data for chemicals, as worker
exposure is primarily a function of the formulation type and the handling activities (e.g.,
packaging type, mixing/loading/application method, and clothing scenario), rather than
chemical-specific properties, (description from website)
EPA
Alan Dixon at dixon.alan@epa.gov or call 703-305-7237 for assistance.
Pesticide exposure data
This source is considered relevant for the CCL Universe because it contains information on
human exposure to pesticides.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.gov/pesticides/science/models db.htm
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Pesticide Product Information System (PPIS)
168
The database contains information concerning all pesticide products registered in the United
States. Information in the data set for each pesticide includes registrant name and address,
chemical ingredients and CAS registry numbers, toxicity category (i.e., danger, warning, and
caution), product names, distributor brand names, site/pest uses, pesticidal type, formulation
code, and registration status. The data are available from a list of zipped ascii files.
EPA
Jim Beech
beech.james@epa.gov
EPA Office of Pesticide Programs
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Mail Code: 7502P
Washington, DC 20460
Name, CASRN, Registrant name and address, Chemical ingredients, Toxicity category,
Product names, Distributor brand names, Site/pest uses, Pesticidal type, Formulation code,
and Registration status
This source is considered relevant for the CCL Universe because it contains an indicator of
possible health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with NPIRS (source 261); however, NPIRS is a subscription source.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.qov/opppmsd1/PPISdata/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Pesticide Product Label System (PPLS)
267
The Pesticide Product Label System is a collection of images, in multi-page TIFF format, of
pesticide labels which have been approved by the Office of Pesticide Programs (OPP) under
Section 3 of the Federal Insecticide, Fungicide, and Rodenticide Act. The collection contains
the initially approved label for pesticide products registered under FIFRA Section 3 as well
as subsequent versions of labels which have changed via amendment or notification.
In addition to the stamped approved labels this collection contains any associated
correspondence about the terms of registration, specifying any changes which the registrant
was required to make in the final printed label. Because some label amendments address
only portions of the label, you may have to review several labels for a single product to
determine the complete terms of registration.
The collection does not identify those products which have been subsequently canceled or
transferred, but rather identifies each pesticide label as it appeared at the time that it was
approved. In additon, please review Limitations of the Pesticide Product Label System.
The label images are indexed by EPA registration number and the date on which the label was
initially registered or amended. If you do not know the registration number, you can search
all federally registered products by active ingredient, product name, or company name, in
EPA's Pesticide Product Information System, which you can access on the California
Department of Pesticide Regulation website at California Department of Pesticide Regulation
(CDPR). (description from website)
EPA
John Jamula
jamula.john@epa.gov
Information Resources and Services Division
Office of Pesticide Programs (7504C)
Environmental Protection Agency
401 M Street SW
Washington, DC 20460
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Ph: 703-305-6426
Fax: 703-305-7670
Name; CAS RN; First aid: if swallowed, if on skin or clothing, if in eyes, if inhaled;
Precautionary statements: hazard to humans and domestic animals warning, environmental
hazards, storage and disposal
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.gov/pesticides/pestlabels/
Data Source Name
Identification Number
Data Source Description
Pesticide Products Databases
268
OPP and the California Department of Pesticide Regulation have developed an interactive
database that offers brief registration information on approximately 89,000 products. The
data include: product number and name, company number and name, registration date,
cancellation date and reason (if canceled), and product manager name and phone number.
Also offered are databases containing chemical ingredient information, searchable by
common, technical, synonym, CAS number, or trade names, and firm information,
searchable by firm number or name.
(description from website)
Proprietor
Contact Information
Type of Data Elements
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
This database serves as a gateway to the information contained in the Pesticide Products
Information System (PPIS). The data dictionary for this source is therefore for data
elements found in PPIS.
EPA/Cal EPA
California Department of Pesticide Regulation
1001 I Street, P.O. Box 4015
Sacramento, CA 95812-4015
General Information:
(916) 445-4300
FAX: (916) 324-1452
Name, Synonyms, CASRN, Company, Registration Date
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with FIFRA.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://www.cdpr.ca.qov/docs/epa/epamenu.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Pesticide Tolerance Index System (TISInfo)
269
The Pesticide Tolerance Index contains a complete listing of pesticide tolerances. TISinfo is
an older DOS based system. However, it is the only electronic version of pesticide
tolerances available at this time from the Office of Pesticide Programs. These databases
are downloadable, self-extracting compressed files. The programs TISINDEX.EXE and
TISINFO.EXE can be used to generate indexes for this data and then to search it and
generate reports from it. (description from website)
EPA
Bernie Schneider
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
schneider.bernard@epa.gov EPA
Office of Pesticide Programs
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Mail Code: 7509P
Washington, DC 20460
Unknown
This source is considered relevant for the CCL Universe because it contains information on
pesticide exposure tolerances.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with NPIRS (source 261); however, NPIRS is a subscription source.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/opprd001/tolerance/tisinfo/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Pesticides Ground and Surface Water Incident Database
259
This electronic database was created in 1999 and contains adverse effects data for
aggregate as well as individual pesticides detected in ground and/or surface water incidents.
A water incident is defined as an occurrence of a pesticide in water at any measurable level.
All of the incident data for this database comes from pesticide manufacturers who are
required to report adverse effects information under section 6(a)(2) of the pesticide law
FIFRA. At the present time, the database contains about 13,200 incident records. Each
record can contain up to 28 fields of information. These water incidents play an important
role in EPA's risk assessment and decision-making process, and are considered in the
Agency's risk assessments for individual pesticides, (description from website)
EPA
Donna Price at Price.Donna@epa.gov or call 703-308-2876
Measurements in water
This source is considered relevant for the CCL Universe because it is being designed to
contain information on pesticide occurrence in water, an indicator of occurrence.
This source has been withdrawn; it is no longer available online.
This source has been withdrawn; it is no longer available online.
This source has been withdrawn; it is no longer available online.
http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name
Identification Number
Data Source Description
Pesticides in Ground and Surface Water Database
260
The Pesticides Program in EPA is in the process of developing a database which contains
information on the presence of pesticides in treated as well as untreated ground and surface
water. Information in this database will be provided by the U.S. Geological Survey, the
Office of Water in EPA, the U.S. Department of Agriculture, other federal and state
agencies, registrants or pesticide manufacturers, and other public entities, such as
universities.
The database will have a series of "canned" search and download features as well as the
ability to customize searches and downloads. In addition, the database will have direct links
to the Office of Water's National Contamination Occurrence Database, STORET, and other
occurrence databases.
Afterthe release of the first version (Release 1), OPP will be populating the database with
other sources of data, such as the Pesticide in Ground Water Database, registrant submitted
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Contact Information
Type of Data Elements
Relevance Explanation
ground and surface water studies, state monitoring programs, and other readily accessible
sources of data.
OPP plans to use the information in this database in developing risk assessments for water
resources, (description from website)
EPA
Sid Abel at Abel.Sid@epa.gov or call 703-305-7346
Occurrence Concentrations (database is under development)
This source is considered relevant for the CCL Universe because it is being designed to
contain information on pesticide occurrence in water, an indicator of occurrence.
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source has been withdrawn; it is no longer available online.
This source has been withdrawn; it is no longer available online.
This source has been withdrawn; it is no longer available online.
http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Pesticides Pilot Monitoring Program - USGS/EPA
164
In 1999, a pilot monitoring program was initiated by EPA and USGS to provide information on
pesticide concentrations in drinking water and to assist in the implementation of the Food
Quality Protection Act (FQPA) of 1996. Twelve water-supply reservoirs were sampled, in
California, Indiana, Ohio, Oklahoma, Louisiana, Missouri, South Carolina, South Dakota, New
York, North Carolina, Pennsylvania, and Texas. Sampling frequencies were designed to
measure long-term mean and short-term peak concentrations of pesticides in drinking water.
The sampling methods included 178 different pesticides and degradation products. The
results of the program were later incorporated in EPA's revised Organophosphate Pesticide
Cumulative Risk Assessment, (description from website)
EPA Office of Ground Water and Drinking Water and USGS NAWQA
Joel Blomquist
U.S. Geological Survey WRD
8987 Yellow Brick Road
Baltimore, Maryland 21237
E-Mail: jdblomqu@usgs.gov
Phone:(410)238-4260
Fax:(410)238-4210
Drinking Water Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://md.water.usas.aov/nawga/abstract.html
Data Source Name
Identification Number
Data Source Description
Plant Toxicity Data
280
PHYTOTOX contains records relating to the biological effects of the application of organic
chemicals to terrestrial plants. Both natural and synthetic organic compounds administered to
native, crop, or weed plant species have been included. The records include data on effects
and on the corresponding scientific source papers.
SUBJECT COVE RAGE:
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Chemical Name Identification
CAS Registry Numbers
Bibliographic References
Biological Effects
Test Conditions
Application Procedures
(description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Information Services Corporation (NISC)/EPA
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
CAS RN, Chemical Name, Stage at application, Stage at recording, Condition at application,
Site of application, Maintenance of plant, Physical state of chemical, Route/method,
Dosage, Effects data, Test Duration, Study grade, Species identification, Source/journal,
Reference number, Author, Publication year, Title
This source does not meet relevance criteria because it contains only information on plant
toxicity.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is redundant with ECOTOX (source 57).
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/phvtotox.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Poisons Information Monographs (PIMs) - IPCS, CCOHS
165
PIMs are part of a global database with evaluated information on substances (chemicals,
Pharmaceuticals, poisonous plants, and poisonous and venomous animals) commonly
involved in cases of poisoning. A PIM is a concise, practical document designed to facilitate
the work of poisons information specialists, clinicians, and analysts.
The PIM is more than a simple monograph and part of a database. It is a dynamic document
which represents an international consensus on the diagnosis, management and prevention
of poisonings. It may also constitute the basis for training, a source of scientific reference
and a stimulus for international cooperation amongst poisons centres and clinical toxicology
units around the world.
The PIMs are prepared by collaborating poisons information centres and other experts
throughout the world and are subjected to individual and peer review. PIMs summarize the
physico-chemical and toxicological properties of the substance, the medical features of the
effects produced by various routes of exposure to the substance, the patient management
and the supporting laboratory investigations, (description from website)
International Programme for Chemical Safety, Canadian Centre for Occupational Health and
Safety, Worldwide Poison Information Centers
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Name, Formula, Synonyms, CASRN, ID numbers, MW, Density, BP, MP, Water Solubility,
Other Solubility, Partition Coefficients, Log Koc, Log Kow, VP, HLC, ADI, MAK, PEL, STEL,
TWA, LCx, LDx, NO(A)EL, LO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
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Completeness Explanation
Redundancy Explanation
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of INTOX (source 105).
Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.org/paaes/pims.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
POLLUAB - Pollution Abstracts
166
POLLUAB is a bibliographic database which contains information on water and air pollution,
sources, and pollution control. The database contains both scientific research and
government policy literature on environmental information, including toxicology and health.
Sources are books, conference proceedings, journals, nontechnical literature, research
reports, and file data from 1981 to the present, with over 195,000 literature references.
(description from website)
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cas.orq/ONLINE/DBSS/polluabss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Pollution Prevention Research and Development Database -
EnviroNET Australia
167
Australia's EnviroNET is a directory of Australia's environment industries including databases
of environment management expertise, industry applications for environmental
technologies, environmental education; plus a range of other resources to support
development and uptake of Australian solutions to industry's environmental issues.
(description from database)
Environment Australia
www.environment.gov.au
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation
It does not meet considerations because there was no documentation on how the data were
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Redundancy Explanation
Retrievability Explanation
Source URL
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.erin.qov.au/net/environet
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Preliminary Remediation Goals (PRGs) - EPA Region 9
169
Preliminary Remediation Goals (PRGs) are tools for evaluating and cleaning up contaminated
sites. They are risk-based concentrations that are intended to assist risk assessors and
others in initial screening-level evaluations of environmental measurements. The PRGs
contained in the Region 9 PRG Table are generic; they are calculated without site specific
information. However, they may be re-calculated using site specific data.
PRGs should be viewed as Agency guidelines, not legally enforceable standards. They are
used for site "screening" and as initial cleanup goals if applicable. PRGs are not de facto
cleanup standards and should not be applied as such. However, they are helpful in providing
long-term targets to use during the analysis of different remedial alternatives. By developing
PRGs early in the decision-making process, design staff may be able to streamline the
consideration of remedial alternatives, (description from website)
EPA Region 9
United States Environmental Protection Agency
REGION IX
75 Hawthorne Street
San Francisco, CA 94105
smucker.stan@epa.gov
PRGs, RfD, Slope Factor, Cancer Risk
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
The relevant data in this source are redundant with ITER and IRIS.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/reaion09/waste/sfund/prg/index.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Priority Substances Assessment Program - Health Canada
170
The Canadian Environmental Protection Act (CEPA) requires the establishment of a Priority
Substances List (PSL). Substances on this List are of priority for assessment to determine
whether environmental exposure to them poses a risk to the health of Canadians or to the
environment. A Priority Substance may be a chemical, a group of chemicals, effluents or
wastes. There have been two PSLs (PSL1 and PSL2),which were established by the Ministers
of Health and of the Environment, based on the recommendations of a Ministers' Expert
Advisory Panel, (description from website)
Health Canada
Contact Information
Inquiry Centre
351 St. Joseph Blvd
Hull, Quebec
K1AOH3
1-800-668-6767
To obtain an electronic version of the Assessment Report in PDF, please request a copy
from the following address: PSL.LSIP@ec.gc.ca
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, Synonyms, CASRN, Formula, BMC, BMD, ENEV, MTD, CTV, ECx, ICx, LDx,
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.ec.ac.ca/substances/ese/eng/psap/final/main.cfm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Priority-based Assessment of Food Additives (PAFA) Database
157
PAFA contains over 3,000 "indirect food additives." It is a list of substances mentioned in
Title 21 of the U.S. Code of Federal Regulations, Parts 175, 176, 177, and 178. "Indirect
food additives" include substances used in "food-contact articles, and include adhesives and
components of coatings, paper and paperboard components, polymers, and adjuvants and
production aids." (description from website)
FDA Center for Food Safety and Applied Nutrition
C.H.I.P.S.
10777 Mazoch Road
Weimar, Texas 78962
Phone (979) 263-5683
Fax (979) 263-5685
http://www.chipsbooks.com/questions.htm
Genetic Toxicity and Cytotoxicology, Acute Toxicology, Oral Toxicology, HNEL,
Toxicological effect, Exposure, ADI, LD High, LEL
This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.chipsbooks.com/fdaddcd.htm
Data Source Name
Identification Number
Data Source Description
Program for Monitoring Emerging Disease (ProMED)
171
ProMED tracks reports of emerging disease in the media and in the medical literature. The
web site offers a variety of information, including archives of ProMED mail, web links, and
other resources concerning emerging diseases, (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Federation of American Scientists
ProMED
1717 KSt., NW
Suite 209
Washington, DC 20036
Voice: (202) 546-3300
Fax: (202)675-1010
E-mail: dpreslar@fas.org
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
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Completeness Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.fas.org/promed/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
PubMed
172
PubMed is a searchable citation and abstract generator for over 4,500 peer reviewed
biomedical journals from the mid-1960s to the present. This bibliographic database is useful
for primary literature on health effects for all types of contaminants, (description from
website)
National Library of Medicine, NCBI, NIH
U.S. National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
email: custserv@nlm.nih.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www4.ncbi.nlm.nih.gov/PubMed/
Data Source Name
Identification Number
PulseNet: The National Molecular Subtyping Network for Foodborne
Disease Surveillance
173
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Source URL
PulseNet is a network of public health laboratories that identify food-borne pathogens to the
molecular level using pulse-field gel electrophoresis. Isolated organism "fingerprints" are
compared to determine if food poisoning has a common source, (description from website)
CDC
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, U.S.A
Tel: (404)639-3311
Public Inquiries: (404) 639-3534 / (800) 311-3435
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
http://www.cdc.gov/pulsenet/what is.htm
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Registry of Toxic Effects of Chemical Substances (RTECS)
180
The Registry of Toxic Effects of Chemical Substances (RTECS®) is a database of
toxicological information compiled, maintained, and updated by the National Institute for
Occupational Safety and Health. The program is mandated by the Occupational Safety and
Health Act of 1970. The original edition, known as the "Toxic Substances List," was published
on June 28, 1971, and included toxicologic data for approximately 5,000 chemicals. Since
that time, the list has continuously grown and been updated, and its name changed to the
current title, "Registry of Toxic Effects of Chemical Substances." As of May 2003, the last
update of the database by NIOSH, RTECS contained 156,485 chemicals as NIOSH strived
to fulfill the mandate to list "all known toxic substances... and the concentrations at which...
toxicity is known to occur."
RTECS® is a compendium of data extracted from the open scientific literature. The data are
recorded in the format developed by the RTECS® staff and arranged in alphabetical order
by prime chemical name. No attempt has been made to evaluate the studies cited in
RTECS®. The user has the responsibility of making such assessments.
RTECS® provides: access to toxicity information for 156,485 chemicals; identification of six
types of toxicity data including: primary irritation, mutagenic effects, reproductive effects,
tumorigenic effects, acute toxicity, other multiple dose toxicity; and includes specific
numeric toxicity values such as LD50, LC50, TDLo, TCLo, and identification of species
studied and route of administration used. Each data line lists the bibliographic source to
indicate actual studies cited, (description from website)
CDC National Institute for Occupational Safety and Health (NIOSH)
The Editor
Registry of Toxic Effects of Chemical Substances
MDL Information Systems, Inc.
200 Wheeler Road, 6th Floor
Burlington, Massachusetts U.S.A. 01803
FAX: (781)272-6868
Distributor of RTECS: Canadian Centre for Occupational Health and Safety
135 Hunter Street East
Hamilton, ON, Canada L8N 1M5
To order: 1 -800-668-4284
General Requests: clientservices@ccohs.ca
Technical Support: technicalsupport@ccohs.ca
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
LDx, NOAEL, LOAEL, Reproductive/ Developmental, Mutation, Irritation, Tumorigenic data
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cdc.gov/niosh/rtecs.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Reregistration Eligibility Decision Documents (REDDs) - EPA OPP
176
"When EPA completes the review and risk management decision for a pesticide that is
subject to reregistration (i.e., one initially registered before November 1984), EPA generally
issues a Reregistration Eligibility Decision (RED) document. The RED summarizes the risk
assessment conclusions and outlines any risk reduction measures necessary for the
pesticide to continue to be registered in the U.S." There are REDs for over 176 pesticides
currently, (description from website)
EPA Office of Pesticide Programs
Special Review and Reregistration Division (7508W)
US Environmental Protection Agency
Office of Pesticide Programs
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Washington, DC 20460
Telephone 703-308-8000
Name, Synonyms, DWLOC, PAD, RfD, MCL, SF, LCx, LDx, LO(A)EL, MOE, NO(A)EL,
HOT
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.aov/pesticides/reregistration/status.htm
Data Source Name
Identification Number
Data Source Description
Resource Conservation and Recovery Information System
275
RCRIS provides comprehensive information on all RCRA hazardous waste handlers in the
US and its territories. These waste handlers include large- and small-quantity generators,
transporters, burner/blenders, incinerators, and TSD facilities.
SUBJECT COVE RAGE:
Facility Location and Identification Data
Handler Classification
Source and Activity Data
Permit Application Data
(description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Name, Address, River basin codes, Ownership type, Quantity and type of hazardous waste
produced, Types of operations conducted at a site
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/rcris.htm
Data Source Name
Identification Number
Data Source Description
Rijksinstituut voor Volksgesondheid en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report
179
Soil Intervention Values are generic soil quality standards based on potential risks to humans
and eco-systems. These values are used to determine whether or not contaminated soils
meet the criteria for "serious soil contamination" as stated in the Dutch Soil Protection Act.
With reference to potential risks to humans, Maximum Permissible Risk (MPR) values,
quantifying the human-toxicological risk limits for some 50 chemicals and chemical classes,
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
were derived in the 1991-1993 period. These MPRs, which have since been updated,
comprise limits on tolerable daily intake, tolerable concentration in air, and oral cancer risk
and/or inhalation cancer risk. In total, the compounds comprise 12 metals (including
cadmium, lead and mercury), 10 aromatic compounds (including the polycyclic aromatics),
13 chlorinated hydrocarbons (including dioxins and polychlorinated biphenyls), 6 pesticides
(including DDT) and 7 other compounds (including cyanides and total petroleum
hydrocarbons). A toxicity profile has been compiled for each compound or compound class.
It consists of a concise summary of the available toxicity data, information on back-ground
exposure and a survey of existing limit values derived by other organisations. An updated
MPR for each compound (or class of compounds) in question is deduced from the
respective profile, (description from website)
Rijksinstituut voor Volksgesondheid en Milieu (RIVM), The Netherlands
RIVM
PO Box 1
3720 BA Bilthoven
The Netherlands
Absorption Factors, ADI, Backgrnd Exposure, CR, Crinhal reliability, Crinhal value, Croral
reliability, Croral value, Dose Ranges, HUM-TOX SCC, IARC Cancer Group, LO(A)EL, MAC,
MPR: oral, inhalation, MRL, MTD, NO(A)EL, Old MPR?, pCRinhal reliability, pCRinhal value,
pCRoral reliability, pCRoral value, Production/Use, pTC(A), pTCA reliability, pTCA value,
pTDI, pTDI reliability, pTDI value, Reliability, TC(A), TCA reliability, TCA value, TD(i/o/lo),
TDI High value, TDI Low value, TDI low/high reliability, TDI reliability, TDI Value, Uncertainty
Factors, WQG
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.rivm.nl/en/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Risk Assessment Information System (RAIS) - Department of
Energy - Chemical Factors
177
This database of chemical-specific factors (i.e., chemical properties) contains values needed
in the human health risk assessment exposure equations to calculate dose or in the human
health risk-based preliminary remediation goal (PRG) equations to calculate the chemical-
specific risk-based PRGs. This database contains information taken from a variety of
sources, and these sources are referenced. If a user needs additional information about the
application or contents of this database, please contact the Center for Risk Excellence at
risk.center@ch.doe.gov. (description from website)
U.S. Department of Energy
Fred Dolislager
University of Tennessee
1060 Commerce Park Drive, MS 6480
Oak Ridge, TN 37830
Phone: (865) 482-5304
E-mail: fdolislager@utk.edu
Name, CASRN, Absorption factor, beef transfer coefficient, BP, Soil to Plant dry uptake,
Soil to Plant wet uptake, Diffusivity in air, Diffusivity in water, Fish bioaccumulation factor,
Gl absorption factor, Gl absorption fraction, Radioactive half life, Soil-water partition
coefficient, Koc, Kp, log Kow, ICRP lung type, milk transfer coefficient, MP, MW, water
This source is considered relevant for the CCL Universe because it contains radioactive
half-life data, providing an indicator of occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
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Retrievability Explanation
Source URL
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://risk.lsd.ornl.gov/rap hp.shtml
Data Source Name
Identification Number
Data Source Description
Risk Assessment Information System (RAIS) - Department of
Energy - Health Effects Data
178
This database of chemical-specific toxicity values contains the human health toxicological
information needed to perform risk evaluations and assessments. This database contains
toxicity information taken from the United States Environmental Protection Agency's (EPA)
Integrated Risk Information System (IRIS), the Health Effects Assessment Summary
Tables (HEAST), and other sources. In this database, all information is referenced.
Additionally, the database contains supplemental information which clarifies some issues.
The database of chemical-specific toxicity metadata contains values needed in human
health toxicity assessments. This database contains information taken from
IRIS/HEAST/NCEA, and these sources are referenced. If a user needs additional information
about the application or contents of this database, please contact the Center for Risk
Excellence at risk.center@ch.doe.gov. (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
U.S. Department of Energy
Fred Dolislager
University of Tennessee
1060 Commerce Park Drive, MS 6480
Oak Ridge, TN 37830
Phone: (865) 482-5304
RfD (critical effect), RfC, Slope Factor, Unit Risk, Absorption Factor, Cancer Class
This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.
http://risk.lsd.ornl.gov/rap hp.shtml
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Risk Based Concentrations (RBCs) - EPA Region 3
175
The RBC Table contains Reference Doses (RfDs) and Cancer Slope Factors (CSFs) for 455
chemicals. These toxicity factors have been combined with "standard" exposure scenarios
to calculate RBCs - chemical concentrations corresponding to fixed levels of risk (i.e., a
Hazard Quotient (HQ) of 1, or lifetime cancer risk of 1 E-6, whichever occurs at a lower
concentration) in water, air, fish tissue, and soil. The equations and the exposure factors are
shown in the RBC Table companion memo, the Technical Background Document. The Region
III toxicologists use RBCs to screen sites not yet on the NPL, respond rapidly to citizen
inquiries, and spot-check formal baseline risk assessments. The primary use of RBCs is for
chemical screening during baseline risk assessment (see EPA Regional Guidance
EPA/903/R- 93-001, "Selecting Exposure Routes and Contaminants of Concern by Risk-
Based Screening"). The exposure equations come from EPA's Risk Assessment Guidance
for Superfund (RAGS), while the exposure factors are those recommended in RAGS or
supplemental guidance from the Superfund program, (description from website, RBC table
cover memo)
EPA Region 3
United States Environmental Protection Agency
REGION III
1650 Arch Street
Philadelphia, Pennsylvania 19103
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
hubbard.jennifer@epa.gov
RBCs, RfD, Slope Factor, SSL
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
The relevant data in this source are redundant with ITER and IRIS.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.aov/reg3hwmd/risk/index.htm
Data Source Name
RISKLINE
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
281
This database includes bibliographic records elaborated by informative abstracts dealing with
human and animal toxicology and carcinogenicity. The database was created by the Swedish
National Chemicals Inspectorate. In some cases, the records relate to publications produced
by toxicological societies and journals. In the main, however, the records relate to
publications produced by industrial and technical associations, governmental agencies, and
international agencies; heavily represented are the following organizations: IARC, ACGIH,
NCI, BIBRA, EPA, NTP, WHO, and ATSDR.
Users can retrieve records by CAS Registry Number (the preferred method) and/or subject
terms/phrases. More than 4,000 unique chemicals are covered in the database. The earliest
records in the database date from 1970, the latest from 2001.
SUBJECT COVE RAGE:
CAS Registry number
Health Hazard Information
Chemical Name
(description from website)
National Information Services Corporation (NISC)/Swedish National Chemicals Inspectorate
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com/cis/details/riskline.htm
Data Source Name
Identification Number
Data Source Description
Safe Drinking Water Information System (SDWIS)
232
The Safe Drinking Water Information System (SDWIS) contains information about public
water systems and their violations of EPA's drinking water regulations, as reported to EPA
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Proprietor
Contact Information
by the states. These regulations establish maximum contaminant levels, treatment
techniques, and monitoring and reporting requirements to ensure that water systems provide
safe water to their customers. This queries help find drinking water supplier and view
violations and enforcement history since 1993.
See UCM - Round 2 (SDWIS/FED) - Unregulated Contaminant Monitoring and NCOD -
National Drinking Water Contaminant Occurrence Database - Round 1&2. Some Safe
Drinking Water Information System (EPA) data contained in these data sources.
EPA
Users can contact EPA using the form located at:
http://www.epa.gov/enviro/html/sdwis/sdwis_feedback.html
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Water System Name, Principal County Served, Population Served, Primary Water Source
Type, System Status, Water System ID, Concentration, Violations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/enviro/html/sdwis/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Screening Information Data Sets (SIDS) - Organisation for Economic
Co-operation and Development (OECD)
182
OECD SIDS contain information collected on 92 chemicals from the HPV chemical list. The
SIDS are produced in a format consistent with IRPTC data files, in order to meet initial
assessment data needs for these chemicals and to generate information that may have
been lacking. SIDS include physicochemical properties, production data, health effects,
analysis effects, use, effects on organisms and ecosystems, environmental fate, and
information on regulatory measures. These data sets may be useful for gathering
physicochemical property and health effects data, including specific endpoints where
available, for any chemicals on the HPV list, (description from website)
International Programme for Chemical Safety, United Nations Environmental Program;
UNEP/IRPTC in Geneva, Switzerland
UNEP Chemicals
11-13 chemin des Anemones,
CH-1219 Chatelaine
Geneva, Switzerland
Tel: (+41 22) 917 8170 and Fax (+41 22) 797 3460
Email: chemicals@unep.ch
Name, Formula, Synonyms, CASRN, Other IDs, ADI, ECx, LCx, LDx, NO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
(LDx, NO(A)EL) from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.chem.unep.ch/irptc/Publications/sidsidex/sidsidex.htm
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Data Source Name
Identification Number
Data Source Description
SOLV-DB
183
SOLV-DB provides health and safety considerations, chemical and physical data, regulatory
responsibilities, and environmental fate data on approximately 325 solvents. In addition
SOLV-DB provides a list of manufacturers for each solvent, a list of all solvents in the
database available from each manufacturer, the "Chemical Abstracts Service (CAS) number"
for each solvent, the identifying designation "Sax Number" from Sax, et al., Dangerous
Properties of Industrial Materials and a table of synonyms. SOLV-DB is searchable by
solvent name, Chemical Abstracts Number, Sax Number, or chemical formula. Additional
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
features for searching include a "Select by Synonym" button to search the database under
another name, a "Select By Chemical Category" button for finding all solvents falling into a
particular chemical family (ketones, aromatic hydrocarbons, CFCs, etc.), a "Select By
Property Range" to find all solvents satisfying a set of criteria, and a "Select By Matching
Text" button to find solvents whose text descriptions contain a specified character string.
When searching by name, CAS number, or Sax number, one will get a general information
table with the most commonly requested information about a solvent. Additional tables with
Health and Safety Data, Chemical-Physical Data, Regulatory Data, and Environmental Fata
Data are also provided. The information tables contain many data elements of specialized
interest, and one may click on the label for each element to retrieve background information
or a definition of the element, (description from website)
National Center for Manufacturing Sciences
Paul Chalmer
National Center for Manufacturing Sciences
paulc@ncms.org , or (734) 995-4911
Name, CASRN, structure, SMILES, formula, MW, BP, FP, VP, viscosity, specific gravity,
refractive index, dielctric constant, evaporation rate, water solubility, log Kow, HLC,
Hildebrand solubility parameter, pKa, pH, azeotrope, surface tension, vapor density, Kauri-
butanol, flash point, heat capacity, heat of vaporization, thermal conductivity, autoignition
temperature, corrosive, color, odor, odor threshold, UV absorption
This source does not meet relevance criteria because it contains only chemical property
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://solvdb.ncms.org/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Source Ranking Database (SRD)
189
SRD was developed to provide a means for systematically reviewing a large number of
consumer products, building materials, and furnishings that are potential sources of airborne
chemicals to which individuals can be exposed while indoors. According to the web site,
SRD "performs a systematic screening-level review of over 12,000 potential indoor pollution
sources to identify high-priority product and material categories for further evaluation, and
can also identify the products that have contained a specific chemical." (description from
website)
EPA OPPT
Richard Wormell
U.S. Environmental Protection Agency
Office of Pollution Prevention and Toxics
1200 Pennsylvania Avenue N.W. (Mail Code 7406M)
Washington, DC 20460
Phone: (202)564-8538
E-mail: wormell.richard@epa.gov
Unknown
This source is considered relevant for the CCL Universe because it has elements that may
indicate possible occurrence and/or possible health effects.
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Completeness Explanation It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates.
http://www.epa.aov/opptintr/exposure/docs/srd.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
State Drinking Water Data Sets
190
These data sets include public water system contaminant occurrence data sets directly from
17 States (with data from 1983 to 2000, but primarily covering 1993 to 1997), which include
the regulated chemical contaminants (particularly the 64 "phase" chemicals) and some States
contain data for unregulated contaminants. The Cadmus Group, Inc. developed these for
EPA and currently maintains extensively edited, working versions of these 17 data sets.
(See National Drinking Water Contaminant Occurrence Database (NCOD) - 6-Year Data.
Most data from the State Drinking Water Data Sets are contained in this data source.)
EPA OGWDW; The Cadmus Group, Inc.
Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
Phone:617-673-7000
Drinking water occurrence concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence. Most data are available for regulated
contaminants. Some data are available for unregulated contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is partially redundant, as it is mostly available as part of NCOD - Six Year
(source 136).
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
State of California EPA Chemicals Known to the State to Cause
Cancer or Reproductive Toxicity
191
Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as
a ballot initiative in November 1986. The Proposition was intended by its authors to protect
California citizens and the State's drinking water sources from chemicals known to cause
cancer, birth defects or other reproductive harm, and to inform citizens about exposures to
such chemicals. Proposition 65 requires the Governor to publish, at least annually, a list of
chemicals known to the state to cause cancer or reproductive toxicity. (description from
website)
State of California
Cynthia Oshita (916) 322-2068 California Office of Environmental Health Hazard
Assessment coshita@oehha.ca.gov Manager
Susan Luong (916) 327-3015 California Office of Environmental Health Hazard Assessment
sluong@oehha.ca.gov Staff
Type of Data Elements
Name, CASRN, Date added to list, Carcinogenicity and Reproductive Toxicity
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.oehha.ca.qov/prop65/prop65 list/files/062802LSTa.pdf
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
State of New Jersey Hazardous Substances Right to Know Fact
Sheets
192
The New Jersey Worker and Community Right to Know Act, which became law in 1983,
requires public and private employers to provide information about hazardous substances at
their workplaces to:
- give public employees information about what hazardous substances are located at their
workplace and how to work with these hazardous substances safely;
- help firefighters, police and other emergency response personnel to adequately plan for
and respond to hazardous substance incidents such as fires, explosions or spills;
- provide data for monitoring and tracking hazardous substances in the workplace and the
environment, (description from website)
State of New Jersey
Program Manager: Richard Willinger
Phone: (609) 984-2202
e-mail: rtk@doh.state.nj.us
Field, Common Name, CAS RN, DOT Number, RTK Substance Number, Date, Revision,
Hazard Summary, Workplace Exposure Limits, Acute Health Effects, Chronic Health
Effects, Cancer Hazard, Reproductive Hazard, Other Long-term Effects
This source is considered relevant for the CCL Universe because it contains information on
carcinogenicity and potential health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.state.ni.us/health/eoh/rtkweb/rtkhsfs.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
STN - CA/CA Plus File - Chemical Abstracts
193
The CA File covers records from 1907 to the present from "international journals, patents,
technical reports, books, conference proceedings, and dissertations from all areas of
chemistry, biochemistry, chemical engineering, and related sciences." As of January 2004,
there are over 22 million records. The CA Plus File also includes all articles from over 1,600
chemical journals since October 1994. (description from website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cas.org/ONLINE/DBSS/cass.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
STN - CHEMLIST/HCHEMLIST - Regulated Chemical Listing
194
CHEMLIST/HCHEMLIST contains lists of chemical substances in national and international
inventories, such as the TSCA Inventory, the European Inventory of Existing Commercial
Chemical Substances, the European List of Notified Chemical Substances, the Canadian
Domestic Substances and Non-Domestic Substances Lists, the Australian Inventory of
Chemical Substances, and others. The list also contains substances subject to regulation
under Title III of the Superfund Amendments and Reauthorization Act, the Resource
Conservation and Recovery Act (RCRA), and a total of 34 other U.S. regulatory lists. HPV
Chemical Lists from Australia and the United States are also included. Over 227,000
records from 1979 to the present are included, (description from website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Substance identity information, inventory status, source of information, and summaries of
regulatory activity, reports, and other compliance information
This source is considered relevant for the CCL Universe because it contains a list related to
health effects or occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.org/ONLINE/DBSS/dbsslist.html
Data Source Name
Identification Number
Data Source Description
STN - DETHERM
195
DETHERM contains over 500 chemical and physical properties for pure inorganic and organic
substances, compound classes, and homologous classes. Substance characteristics cover
thermodynamic, electric, transport, surface, and electrochemical properties, as well as
property relation and bibliographic information. The database consists of both factual
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
records (data tables) and citations. Sources include scientific journals, conferences,
handbooks, manufacturers' data, reports, standards, and file data. There are over 449,000
data tables and 53,000 bibliographic records in the database, (description from website)
Chemical Abstracts Service; Produced by DECHEMA e.V. and FIZ CHEMIE GmbH
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Name, CASRN, Thermodynamic Properties, Multicomponent System Properties, Electric
Properties, Transport Properties, Surface Properties, Electrochemical Properties, Property
Relation Information, Data Type Information, State-of-System Information, Bibliographic
Information
This source does not meet relevance criteria because it contains only chemical property
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Completeness Explanation
Retrievability Explanation
Source URL
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.orq/ONLINE/DBSS/dethermss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
STN - Handbook Of Data on Organic Compounds Database (HODOC)
196
HODOC is a numeric database that contains information from the nine-volume 2nd edition of
the Chemical Rubber Company (CRC) Handbook of Data on Organic Compounds.
According to the web site, "the HODOC File features the most frequently used physical and
chemical data of organic compounds and is an extensive source of spectral data." Chemical
data include optical, physical property, and spectral data fora total of more than 25,000
organic substances, (description from website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Name, CASRN, Chemical Data, Chemical Engineering, Chemistry, Engineering, Optical
Properties, Physical Properties, Property Data, Spectral Data, Crystal property description,
Density, MW, MP, formula, formula weight, refractive index, solubility, specific gravity
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.org/ONLINE/DBSS/hodocss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
STN - Merck Index Online (MRCK)
197
MRCK is the online version of the published Merck Index, 11th edition. It contains 10,415
records (as of April 2004) for chemicals, drugs, biologicals, and agricultural products.
Records include chemical, generic, and trade names; CAS numbers; molecular formulas;
therapeutic and commercial uses; structures; bibliographic citations to scientific literature;
and physical and toxicity properties from the late nineteenth century to the present.
Sources in the index include journals, books, patents, government reports, conference
proceedings, and file data, (description from website)
Chemical Abstracts Service; Merck & Co., Inc.
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Chemical Name, Chemical Name of Derivative, Company Name, Molecular Formula, Boiling
Point, Pressure, Refractive Index of Parent Substance
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.cas.orq/ONLINE/DBSS/mrckss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
STN - NUMERIGUIDE
198
NUMERIGUIDE contains "information on all of the numeric properties available in each
numeric database on STN, including appropriate terminology for each property, property
definition, files in which the property may be searched for, and default units for the property
in each file." The file contains records on more than 875 types of numeric properties (as of
March 2002) and covers all of the STN numeric files, (description from website)
Chemical Abstracts Service; American Chemical Society (ACS)
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Name, Accession Number, Field Qualifiers, Notes, Preferred Property Name, Used For, All
fields containing hit terms, List of display fields containing hit terms, All Associated Terms,
Broader Terms, Definition, Description, STN File Name(s), Field, Qualifier(s), Display Field
Qualifier(s), Search Field Qualifier(s), Hierarchy Terms, Keyword Terms, Narrower Terms, All
Preferred and Forbidden Terms, Used For Terms, Units, Use Terms
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
Retrievability Explanation
Source URL
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.ora/ONLINE/DBSS/numeriguidess.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
STN - Toxicology Center (TOXCENTER)
199
TOXCENTER is a bibliographic database that draws on four other databases: BIOSIS, CA
Plus, IPA, and MEDLINE. Relevant information includes literature from 1907 to the present
on carcinogenesis, chemically-induced diseases, environmental pollution, food
contamination, mutagenesis, teratogenesis, and toxicological analysis for drugs and other
chemicals such as agricultural pesticides. Sources include books, bulletins, conference
proceedings, letters, journal articles, meetings, monographs, notes, papers, patents,
presentations, research and project summaries, reviews, technical reports, and file data, for
a total of over six million records (as of April 2004). (description from website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation It meets considerations because it meets all NDWAC minimum data requirements.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.cas.ora/ONLINE/DBSS/toxcenterss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
STN - ZREGISTRY
200
The ZREGISTRY File is a chemical structure and dictionary database containing unique
substance records for compounds identified by the CAS Registry System. The file contains
records for all substances in the CAS Registry System, and provides the CAS registry
number and index name, synonyms, molecular formulas, nucleic acid and protein
sequences, ring analysis data, structure diagrams, and calculated physical properties for
over 12 million single-component organic substances. This file also lists the ten most recent
articles from the CA database citing the particular compound being searched for, and the
total number of CA citations for a substance, (description from website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Name, CASRN, structure, STN files, HE data, MP, BP, BCF, Koc, LOGO, molar solubility,
MW, pKa; alloy composition tables, classes for polymers, nucleic acid and protein
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
sequences, ring analysis data, and structure diagrams; other phys prop
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.ora/ONLINE/DBSS/zregistrvss.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
STN and STN Easy - Scientific and Technical Information Network
201
STN provides a tool to search through over 200 scientific, technical, business, and patent
databases. Available data files cover a range of scientific fields, including many relevant to
drinking water contaminants (e.g., production, use, physicochemical properties,
environmental fate, and health effects). Twenty-four databases are directly relevant to
drinking water contaminant information gathering. In general, little or no occurrence
information is available through the searchable databases, but a range of physicochemical
property and health effects data are available. Most of the 24 relevant databases are
bibliographic, with only a few numeric databases divided into specific records for different
chemicals. In addition, the few numeric databases that exist in STN are chemical property
databases, and do not include direct information on human health effects. STN Easy is a
web-only database searching tool, including 80 of the 200 STN databases, (description from
website)
Chemical Abstracts Service
Chemical Abstracts Service
2540 Olentangy River Road
P. O. Box 3012
Columbus, OH 43210-0012
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.cas.org/stn.html
Data Source Name
Identification Number
Data Source Description
STORET - STORage and RETrieval
202
STORET is a water quality and biological and physical property data warehouse, containing
information from over 60 organizations in a new database from 1999, with access to pre-
1999 data starting from the 1960s. Organizations report on projects and other sampling
efforts, and this information is then made available to users, (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
EPA
STORET User Assistance: 1-800-424-9067 or STORET@epa.gov
Estimated, Nitrogen, ammonia (NH3) as NH3 (mg/l), Estimated, Fecal Coliform (#/100ml),
Estimated Total Coliform (#/100ml)
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/storet/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Structure and Nomenclature Search System
271
Structure and Nomenclature Search System (SANSS) is designed to contain an entry for
each compound included in the other individual Chemical Information System (CIS)
databases. It also provides cross-reference referral capabilities to many other sources of
chemical information, enabling you to find additional data that may not be available online
through CIS.
SUBJECT COVE RAGE:
CAS Registry Number
Chemical Abstracts Service name (8th or 9th Collective Index)
Synonyms and trade names
Molecular formula
Molecular weight
Structural diagram
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Name, CASRN, Synonyms and trade names, Molecular formula, Molecular weight, Structural
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
diagram
This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.nisc.com/cis/details/sanss.htm
Data Source Name
Substance Registry System (SRS)
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
203
The SRS is part of a single metadata registry, EDR, referencing EPA information resources.
The system integrates several collections of EPA metadata, including data elements and
chemical identification information. SRS is EPA's central system for chemical and biological
identification information, providing a common basis for identification of chemicals listed in
EPA regulations and data systems, as well as chemicals of interest from other sources. The
database contains name and regulation information for over 83,000 substances from 95
information resources, (description from website)
EPA
Users can contact EPA using a form at the following location:
http://oaspub.epa.gov/srs/feedback$. startup
CAS RN, Classification, Molecular Formula, Molecular Weight, Regulatory Resources, Other
Sources, Group/Component, Related Links
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
SRS is retrievable by EPA. SRS is EPA's registry and provides the identifying EPA data
standards for the CCL substances.
http://www.epa.gov/srs/index.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Superfund Contract Laboratory Program (SCLP) Water/Soil Data
181
Superfund CLP is a national network of EPA personnel, commercial laboratories, and
contractors that support EPA's Superfund effort by providing data of known and documented
quality. According to the web site, "since the inception of the CLP in 1980, more than 500
CLP laboratories have analyzed over 1,500,000 samples from more than 12,000 sites....over
1,850,000 soil and water samples for more than 150 chemicals from more than 10,000 sites
representing all ten EPA regions have been analyzed by over 430 laboratories." Data are
compiled in the CLP Analytical Results Database (CARD) and maintained by the Analytical
Operations Center, (description from website)
EPA Headquarters Analytical Operations/Data Quality Center (AOC) in the Office of
Emergency and Remedial Response (OERR)
EPA Region 6 Main Office
1445 Ross Avenue
Suite 1200
Dallas, Texas 75202
(214) 665-6444
Mean, Min, Max, Median, Measured/Estimated Concentrations
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/earth1r6/6lab/hlclp.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Syracuse Research Corporation (SRC) - BIODEG
251
BIODEG contains experimental values as in CHEMFATE, but only relating to biodegradation
subjects. In addition, BIODEG contains evaluation codes that can be used for
structure/biodegradability correlations. This file contains over 5,800 records of actual
experimental results on biodegradation studies for approximately 800 chemicals.
Experimental details, such as chemical concentration and rate of degradation, are included.
(description from website)
Syracuse Research Corporation
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone: (315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com
Name, CASRN, Biodegradation - aerobic, anaerobic, soil, sediment, sewage, fresh water,
seawater, other
This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be used as an indicator of potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.svrres.com/esc/efdb.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Syracuse Research Corporation (SRC) - BIOLOG
254
BIOLOG, or the Microbial Degradation/Toxicity File, provides sources of microbial toxicity
and biodegradation data. It is is more detailed than DATALOG, but does not include
experimental values. BIOLOG contains 70,000 records on 8,150 chemicals, (description
from website)
Syracuse Research Corporation/EPA
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com
Name, CAS RN, Formula, Biodeg-Tox, Oxygen Cond, Culture, Source, Mechanism, Data
Source
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.svrres.com/esc/efdb.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Syracuse Research Corporation (SRC) - CHEMFATE
252
CHEMFATE is a data value file containing 25 categories of environmental fate and
physical/chemical property information on commercially important chemical compounds.
Actual experimental values (rate constants, experimental conditions, physical properties,
etc.) are abstracted and retained in the file. CHEMFATE contains 17,260 records on 1,728
chemicals. Recently, recommended physical property values were collected for the SARA
Section 313 TRI chemicals, (description from website)
Syracuse Research Corporation
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax: (315)452-8440
E-mail: escwebmaster@syrres.com
Name, CASRN, MW, formula, MP, BP, UV absorption, pKa, log Kow, water solubility, VP,
HLC, evaporation from water, soil adsorption constant, soil column transport, soil think layer
chromotography, log bioconcentration factor, hydrolysis, oxidation and other reactions,
photolysis, microbial degradation, degradation in natural systems, ecosystem, air monitoring,
water monitoring, soil monitoring, biota monitoring, field studies
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.svrres.com/esc/efdb.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Syracuse Research Corporation (SRC) - Chemical Pointer File
184
The Chemical Pointer File contains pointers to important lists and inventories to each of the
25,000-plus chemicals in the file is listed. For instance, the pointers indicate if the chemical
is on EPA lists, on the TSCA inventory, in the NLM's database, in individual SRC EFDB
files, in the Pomona College MEDCHEM database, and in the University of Arizona's
ARIZONA dATABASE of water solubility values, (description from website)
Syracuse Research Corporation
Dr. Philip Howard
Phone:(315)452-8417
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Main Phone: (315) 452-8400
Fax: (315)452-8440
E-mail: escwebmaster@syrres.com
Name, CASRN, structure, status on number of lists
This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.
Completeness Explanation It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation
This source is not redundant.
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Retrievability Explanation
Source URL
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.svrres.com/esc/chemical pointer.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Syracuse Research Corporation (SRC) - DATALOG
253
DATALOG is a bibliographic file indexed by Chemical Abstract Service (CAS) registry
number that contains eighteen types of environmental fate data. Since individual articles
require only cursory examination, no experimental values are entered into the file, and thus,
large numbers of chemicals can be rapidly incorporated. This file is the largest in the EFDB,
containing 380,000 records on over 16,800 chemicals. DATALOG indicates where
environmental fate and exposure data can be found by using the following 18 different
indexing terms:
Adsorption
Bioconcentration
Biodegradation
Dissociation constant
Ecosystems
Effluent concentrations
Evaporation from water
Field studies
Food and crop concentrations
Henry's Law constant
Hydrolysis
Monitoring
Occupational concentrations
Octanol/water partition coefficent
Photooxidation
UV spectra
Vapor pressure
Water solubility
(description from website)
Syracuse Research Corporation/EPA
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone: (315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.svrres.com/esc/efdb.htm
Data Source Name
Syracuse Research Corporation (SRC) - Environmental Fate
Databases (EFDB)
Identification Number
Data Source Description
185
"EFDB is comprised of several interrelated files, DATALOG, CHEMFATE, BIOLOG, and
BIODEG. These databases share a CAS registry number file containing over 20,000
chemicals with preferred name and formula, and a bibliographic file containing full references
on over 35,000 articles cited."
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
BIODEG Description: BIODEG contains experimental values relating to biodegradation
studies. BIODEG also includes information that may be used for "structure/biodegradability
correlations." The file contains records on a total of about 800 chemicals. This file may be
useful for identifying detailed biodegradation data. MS Windows version fee is $100.00.;
BIOLOG Description: BIOLOG "provides sources of microbial toxicity and biodegradation
data. It is more detailed than DATALOG but does not include experimental values." The
database contains records for 8,000 chemicals. This database may be useful for examining
biodegradation of potential drinking water contaminants. MS Windows version fee is
$100.00.;
CHEMFATE Description: CHEMFATE "is a data value file containing 25 categories of
environmental fate and physical/chemical property information on commercially important
chemical compounds. Actual experimental values are abstracted and retained in the file."
This database contains data for a total of 1,728 chemicals, including physical property
values for Superfund Amendments and Reauthorization Act (SARA) Section 313 TRI
chemicals. This database may be useful for physicochemical properties for a wide range of
potential drinking water contaminants. MS Windows version fee is $100.00.;
DATALOG Description: DATALOG is a bibliographic file containing 18 types of environmental
fate data such as bioconcentration, hydrolysis, and water solubility. The database is
indexed by CAS registry numbers, and contains data for over 16,500 chemicals. Data are
not extracted from bibliographic references, and need to be retrieved manually for entry into
another database. This file may be useful for gathering environmental fate data, such as
water solubility, on a wide range of potential drinking water contaminants. MS Windows
version fee is $200.00. (description from website)
Syracuse Research Corporation; developed under the sponsorship of EPA, with support from
Dupont, Proctor & Gamble, and EPA for web version
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone: (315)452-8400
Fax: (315)452-8440
E-mail: escwebmaster@syrres.com
References relating to: Adsorption, Bioconcentration, Biodegradation, Dissociation constant,
Ecosystems, Effluent concentrations, Evaporation from water.Field studies, Food and crop
concentrations Henry's Law constant, Hydrolysis, Monitoring, Occupational concentrations,
Octanol/water partition coefficent, Photooxidation, UV spectra, Vapor pressure, Water
solubility, Biodeg-Tox, Oxygen Cond., Culture, Source, Mechanism, Data Sources, CAS RN
This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be used as an indicator of potential occurrence.
It meets considerations because all of the sources it includes either meet all NDWAC
minimum data requirements or are peer reviewed.
This source is redundant. It is available as a suite of data sources: BIOLOG, BIODEG,
CHEMFATE, and DATALOG.
This source does not meet retrievability criteria because it is only available through a
subscription.
Data Source Name
Identification Number
Syracuse Research Corporation (SRC) - Physical Property Database
(PHYSPROP)
186
Data Source Description
The Physical Properties Database (PHYSPROP) contains chemical structures, names and
physical properties for over 25,250 chemicals. PHYSPROP has very limited data on
inorganic chemicals. The physical properties provided by PHYSPROP were gathered from a
variety of sources, and include experimental, extrapolated, and estimated values for melting
point, boiling point, water solubility, octanol-water partition coefficient, vapor pressure, pKa,
Henry's law constant, and OH rate constant in the atmosphere.
PHYSPROP is available in ISISBase format (MDL Information Systems, Inc.). This program
allows PHYSPROP to be searched by substructure, name fragment, or any of the physical
properties. PHYSPROP is also available in SD File, MS-Excel97, and MS-Access formats.
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
An on-line interactive demo version is also available which retrieves data for a subset of
some 25,000 chemicals from the PHYSPROP database. This free on-line database is
searchable by CAS Registry Number. However the on-line demo only contains basic data
for chemicals and does not provide full reference citations or structure depictions. The on-
line demo does not have the sub-structure searching capabilities that are available with the
ISIS/Base (MDL Information Systems, Inc) version or Accord for Access (Synopsys
Scientific Systems, Ltd) version of PhysProp. (description from website)
Syracuse Research Corporation
Main Number (315) 452-8400 Fax Number (315)452-8440
Mailing Address 301 Plainfield Road, Suite 350 Syracuse, New York 13212-2510
escwebmaster@syrres.com
Name, CASRN, MW, formula, structure, experimental, extrapolated, and estimated values
for melting point, boiling point, water solubility, octanol-water partition coefficient, vapor
pressure, pKa, Henry's law constant, and OH rate constant in the atmosphere
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.svrres.com/esc/phvsprop.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Syracuse Research Corporation (SRC) - Simplified Molecular Input
Entry System (SMILECAS Database)
187
SMILECAS contains SMILES notations for molecular structures of over 103,000 compounds
used in developing structure-activity relationships.
Available for free download at:
http://www.epa.gov/oppt/exposure/docs/episuitedl.htm
(description from website)
Syracuse Research Corporation/EPA
Mailing Address:
301 Plainfield Road, Suite 350
Syracuse, New York 13212-2510
escwebmaster@syrres.com
Main Number (315)452-8400
Fax Number (315) 452-8440
CAS RN, Chemical Name, SMILES notation
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.
This source is redundant with NCI-3D (source 135).
This source meets retrievability criteria because it is in tabular format.
http://www.svrres.com/esc/smilecas.htm
Data Source Name
Identification Number
Data Source Description
Terrestrial Toxicity Information
282
The TERRETOX database contains records related to the toxic effects of chemical
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
substances on terrestrial animals. It deals primarily with mammals and birds, although some
insects, amphibians and other species are included.
SUBJECT COVE RAGE:
Assay Results/Analysis
CAS Registry Numbers
Chemical Name Identification
Environmental Effects
Species Identification
Test Conditions
Toxicology
(description from website)
National Information Services Corporation (NISC)/EPA
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is redundant with ECOTOX (source 57).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com/cis/details/terretox.htm
Data Source Name
Identification Number
Data Source Description
The Institute for Genomics Research (TIGR) Microbial Database
207
The Institute for Genomics Research (TIGR) microbial database catalogs over 60 published
microbial genomes and genomes in progress. Some notable enteric microbes' genomes
have been published, including Campylobacter jejuni, E. Coli O157: H7, Helicobacter pylori,
Pseudomonas aeruginosa, Salmonella typhi and typhimurium, and Vibrio cholerae.
(description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The Institute for Genomics Research (TIGR)
tdb@tigr.org
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.tiar.orq/tdb/mdb/mdbcomplete.html
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The Manual of Clinical Microbiology, 7th edition.
205
The Manual is a reference for clinical microbiologists, pathologists, clinicians, and students.
Coverage includes general issues in clinical microbiology, the clinical microbiology lab in
infection control and prevention, diagnostic technologies in clinical microbiology,
bacteriology, virology, mycology, parasitology, antimicrobial agents and susceptibility
testing, and reagents, stains, and media. This edition is enhanced by perspectives from
editors and authors outside the US. Some material is consolidated and reorganized.
(description from website)
American Society for Microbiology
Ordering information available: http://www.amazon.com/exec/obidos/tg/detail/-
/1555811264/102-1971644-1055309?v=glance
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.amazon.eom/exec/obidos/tg/detail/-/1555811264/102-1971644-1055309?v=glance
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
The National Environmental Methods Index (NEMI)
138
NEMI is a web-based index of analytical methods. The purpose of NEMI is to provide a
unified, easy-to-access source for methods. This database focuses on methods appropriate
for detection in ambient water, (description from website)
USGS
Although there is not an official help desk for NEMI, help regarding technical problems with
the use of this site is available within the United States at 608-821-3869 during regular
business hours Monday through Friday.
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.nemi.gov
Data Source Name
Identification Number
Data Source Description
Proprietor
The Office of Ground Water and Drinking Water (OGWDW)
Consumer Fact Sheets
153
These fact sheets comprise a text-based summary of information on health effects,
releases to water, and occurrence for over 90 regulated drinking water contaminants.
(description from website)
EPA Office of Ground Water and Drinking Water
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Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Safe Drinking Water Hotline - 800-426-4791
hotline-sdwa@epa.gov
What is CHEMICAL, and how is it used?, Why is CHEMICAL being regulated?, What are the
Health Effects?, How much CHEMICAL is produced and released?, What happens to
CHEMICAL when it is released?, How will Chemical be Detected in and Removed from My
Drinking Water?, How will I know if Chemical is in my drinking water?, Drinking Water
Standards (MCLG, MCL), Releases to Water and Land
This source does not meet relevance criteria because it contains only information for
regulated contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/safewater/hfacts.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
The Office of Ground Water and Drinking Water (OGWDW) -
Technical Fact Sheets
154
Technical fact sheets are published on the web by OGWDW, and include chemical and
physical properties, trade names for the chemical, and other regulatory information.
(description from website)
EPA Office of Ground Water and Drinking Water
Safe Drinking Water Hotline - 800-426-4791
hotline-sdwa@epa.gov
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria because it contains only information for
regulated contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.epa.gov/safewater/hfacts.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
The Open Practical Knowledge Acquisition Toolkit (TOPKAT)
240
TOPKAT is a commercial computational toxicology package that uses chemical structural
information (2-D descriptors of structural fragments) and QSAR models to estimate a range
of human health toxicological and non-human ecological endpoints. Predictions are made for
untested chemicals by comparison with structural fragments contained in the model's
training set. It is one of a number of toxicological QSAR packages available, as reviewed
previously in "Status and Feasibility of Using (Quantitative) Structure-Activity Relationships
((Q)SAR) for CCL Development" July, 2003. (description from website)
Accelrys
Accelrys
9685 Scranton Road
San Diego
CA92121
Phone: (800) 756-4674
Phone: (858) 799-5509
Fax: (858)799-5102
E-mail: support-us@accelrys.com
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
SMILES, Compund Name, Primary ID, Secondary ID, Rodent Carcinogenicity, Ames
Mutagenicity, Rat Oral LD50, Rat Chronic LOAEL, Developmental Toxicity Potential, Skin
Sensitization, Fathead Minnow LC50, Daphnia Magna EC50, Weight of Evidence Rodent
Carcinogenicity, Rat Maximum Tolerated Dose, Aerobic Biodegradability, Eye Irritancy, Log
P, Rabbit Skin Irritancy, Rat Inhalation Toxicity LC50, Rat Maximum Tolerated Dose
This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a
http://www.accelrvs.com/products/topkat/
Data Source Name
Identification Number
Data Source Description
The Prokaryotes: A handbook on the biology of bacteria:
Ecophysiology, Isolation, Identification, and Applications
206
The Prokaryotes provides information on prokaryotic ecophysiology and biochemistry,
prokaryotoc organisms, symbiotic associations, and biotechnology.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Balows, A et al. (ed.), Springer-Verlag, New York (4 volumes)
springerlink@springer-ny.com
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://141.150.157.117:8080/prokPUB/index. htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
The Toxics Release Inventory (TRI)
212
TRI contains information from almost 23,000 U.S. companies and government facilities that
report their air, land, and water releases of industrial chemicals and other waste management
activities. TRI also contains some information about source reduction efforts. This
database's information on releases to water are a valuable source of potential occurrence
data for screening drinking water contaminants. It includes many categories of air, land, and
water release data for the years 1988 through 2001. As of April, 2004, "the TRI toxic
chemical list contains 582 individually listed chemicals and 30 chemical categories (including
three delimited categories containing 58 chemicals). If the members of the three delimited
categories are counted as separate chemicals then the total number of chemicals and
chemical categories is 667 (i.e., 582 + 27 + 58)." (description from website)
EPA
TRI Program Division
Phone: 202-566-0250
Email: tri.us@epa.gov
Chemical releases to air, land, and water
This source is considered relevant for the CCL Universe because it contains information on
chemical releases, which may indicate potential occurrence.
It meets considerations because it is peer reviewed.
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Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.epa.gov/triexplorer/
Data Source Name
Identification Number
Data Source Description
TOMES PLUS, MICROMEDEX - Thomson-Micromedex
208
The TOMES Plus® System offers access to medical, environmental, and hazard information
needed for safe management of chemicals. Its vast array of references includes licensed
as well as proprietary databases available only from MICROMEDEX. The System's unique
Integrated Index® feature saves valuable time by searching all databases simultaneously
using more than 2.1 million synonyms. All data are prepared and reviewed by experts in the
fields of environmental, industrial, and reproductive toxicology; occupational medicine; and
industrial hygiene and safety, (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Thomson Micromedex
Phone: (800) 525-9083, press option 4,2
Fax: (800) 635-6339
Email: mdx.custsvc@thomson.com
Identification & Synonyms, Range of Toxicity, Toxicity/Biomedical Effects, Environmental
Fate/Exposure Potential, Chronic Health Hazard Assessments for Non-Carcinogenic Effects,
Carcinogenicity Assessments for Lifetime Exposure
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.micromedex.com
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Total Exposure Assessment Methodology Study (TEAM)
250
The Total Exposure Assessment Methodology (TEAM) study was designed to develop
methods to measure individual total exposure (exposure through air, food, and water) and
resulting body burden of toxic and carcinogenic chemicals, and to apply these methods
within a probability-based sampling framework to estimate the exposures and body burdens
of urban populations in several U.S. cities. The TEAM Study reports the results of eight
monitoring studies performed in five communities during different seasons of the year.
Breath, personal, outdoor, and water samples were collected for volatile organic compounds.
Results of the TEAM Study are reported in a four volume report entitled: The Total
Exposure Assessment Methodology (TEAM) Study. Two of the four volumes provide data in
a form that can be incorporated into Version 2 of the Endocrine Disrupter Priority-Setting
Database (EDPSD v.2). These volumes are: (1) The Total Exposure Assessment
Methodology (TEAM) Study: Elizabeth and Bayonne, New Jersey, Devils Lake, North
Dakota, and Greensboro, North Carolina: Volume II. Part 2 and (2) The Total Exposure
Assessment Methodology (TEAM) Study: Selected Communities in Northern and Southern
California: Volume III. Altogether the TEAM Study provides data on 30 volatile organic
compounds from breath, personal air, outdoor air, and water samples. Table 1 lists the
compounds and provides information on the media for which data is reported for them.
U.S. Environmental Protection Agency, Office of Acid Deposition, Environmental Monitoring
and Quality Assurance. Project Summary: The Total Exposure Assessment Methodology
(TEAM) Study. EPA-600-S6-87-002, 1987. (description from ERG)
EPA
EPA/Eastern Research Group
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
703-633-1600
Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season
This source is considered relevant for the CCL Universe because it contains information on
potential health effects.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Source URL
N/A
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Toxic Substances Control Act (TSCA) List
288
The Toxic Substances Control Act (TSCA) of 1976 requires the Environmental Protection
Agency (EPA) to maintain a list of chemical substances that have been manufactured,
imported, or processed in the United States for commercial purposes since January 1, 1975.
The TSCA contains this list and is commonly referred to as the TSCA Inventory. Note that
the database contains only the public portion of the Inventory; a supplemental, "confidential"
portion of the Inventory is maintained by EPA.
EPA
Unknown
This source is considered relevant for the CCL Universe because it is a list and contains
information on production volume, which may indicate potential occurrence.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is accessible through EPA's Substance
Registry System.
Data Source Name
Health
Identification Number
Data Source Description
Proprietor
Contact Information
Toxicity Criteria Database - California Office of Environmental
Hazard Assessment (OEHHA)
209
The Toxicity Criteria Database contains information on over 260 chemicals. The database
reports information that includes the following: cancer potency information (oral/inhalation
slope factors), chronic and acute Reference Exposure Levels (RELs), California Public
Health Goals (CPHG), California Proposition 65 No Significant Risk Levels (NSRLs), and
Maximum Allowable Daily Levels (MADLs).
The Technical Support Document for Describing Available Cancer Potency Factors (TSD)
contains cancer unit risks and potency factors for 121 of the 201 carcinogenic substances
or groups of substances for which emissions must be quantified in the Air Toxics Hot Spots
program. The purpose of this document is to provide a summary of the data supporting the
carcinogenic potential of the substance or group of substances and to provide the calculation
procedure used to derive the estimated unit risk and cancer potency factors. For the
complete document, go to http://www.oehha.ca.gov/air/cancer_guide/TSD2.html to download.
(Description from website)
California Office of Environmental Health Hazard Assessment
Office of Environmental Health Hazard Assessment
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Type of Data Elements
California Environmental Protection Agency
1515 Clay Street, 16th Floor
Oakland, California 94612
(510) 622-3200
Critical effect, CAMCL, CAPHG, cancer risk, cancer groups, MADL, NSRL, REL, slope
factor, unit risk
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.oehha.ca.gov/risk/ChemicalDB/index.asp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
TOXLINE
211
TOXLINE is the National Library of Medicine's extensive collection of online bibliographic
information covering the biochemical, pharmacological, physiological, and toxicological
effects of drugs and other chemicals. It contains more than 3 million bibliographic citations,
almost all with abstracts and/or indexing terms and CAS Registry Numbers. TOXLINE
references are drawn from various sources grouped into two major parts-TOXLINE Core and
TOXLINE Special - both of which operate under versatile search engines offering a variety of
search and display capabilities.
Components of Toxline Special:
Special journal and other research literature: Developmental and Reproductive Toxicology
(DART®®), International Labour Office (CIS), Swedish National Chemicals Inspectorate
(RISKLINE)
Technical reports and research projects: Federal Research in Progress (FEDRIP), Toxic
Substances Control Act Test Submissions (TSCATS), Toxicology Document and Data
Depository (NTIS), Toxicology Research Projects (CRISP)
Archival collection (no longer being updated): Aneuploidy (ANEUPL), Environmental Mutagen
Information Center File (EMIC), Environmental Teratology Information Center File (ETIC),
Epidemiology Information System (EPIDEM), Hazardous Materials Technical Center (HMTC),
Health Aspects of Pesticides Abstract Bulletin (HAPAB), International Pharmaceutical
Abstracts (IPA), NIOSHTIC (NIOSH), Pesticides Abstracts (PESTAB), Poisonous Plants
Bibliography (PPBIB), Toxicological Aspects of Environmental Health (BIOSIS)
(description from website)
National Library of Medicine; created by NLM, maintained by the Toxicology and
Environmental Health Information Program (TEHIP)
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone: (301)496-1131
FAX (301) 480-3537
e-mail: tehip@teh.nlm.nih.gov
URL: http://sis.nlm.nih.gov
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
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Source URL
http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen?TOXLINE
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
TSCA Plant and Production
284
The U.S. Toxic Substances Control Act (TSCA) required the establishment of an inventory of
the many chemicals found in U.S. commerce during the period 1975 through 1977. This
inventory was generated by the manufacturers and importers of chemical substances in
commercial quantities. Processors and users also reported chemicals that they used.
SUBJECT COVE RAGE:
Chemical Name Identification
CAS Registry Number
Manufacturer Address Information
Production Volume
Plant Site Information
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Name, CASRN, Manufacturer Address Information, Production Volume, Plant Site Information
This source is considered relevant for the CCL Universe because it is a list and contains
information on production volume, which may indicate potential occurrence.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/tscapp.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
TSCATS - Toxic Substances Control Act Test Submissions
213
TSCATS "is a central system for the collection, maintenance, and dissemination of
information on unpublished technical reports submitted by industry to EPA under TSCA.
Studies on over 8,000 chemicals are categorized into three broad subject areas (i.e., health
effects, environmental effects, and environmental fate)." TSCATS draws on 81,000 studies
on 8,000 chemical substances. The database includes data on chemical exposure studies,
epidemiology, environmental fate, monitoring, and episodic incidents, such as spills and
case reports, (description from website)
Syracuse Research Corporation; Developed and maintained by SRC for EPA
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone: (315)452-8400
Fax: (315)452-8440
E-mail: escwebmaster@syrres.com
CAS RN, Name, Study Purpose, Organism, Rte Admin, Test, Ref
Relevance Explanation
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.svrres.com/esc/tscats info.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
UCM - Round 2 (SDWIS/FED) - Unregulated Contaminant Monitoring
214
UCM-Round 2 contains actual monitoring results (i.e., parametric data) from drinking water
PWSs used to support occurrence analyses for various OGWDW projects (from 1992-1997).
The Safe Drinking Water Information System/Federal Version (SDWIS/FED) generally
covered the Round 2 unregulated contaminant monitoring period. These data were originally
submitted by the States drinking water agencies to EPA and stored in SDWIS/FED. The
Cadmus Group, Inc., currently maintains the extensively edited, working version here
referred to as UCM-Round 2 (SDWIS/FED). The database covers 48 contaminants,
including unregulated lOCs, unregulated SOCs, and mandatory and discretionary VOCs for
33,800 PWSs. A detailed description of this data source can be found in Occurrence of
Unregulated Contaminants in Public Water Systems: An Initial Assessment (EPA, 2001; EPA
815-P-00-001).
The Cadmus Group, Inc.; EPA OGWDW
Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
T: 617-673-7000
F: 617-673-7001
Drinking Water Occurrence Concentrations
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is redundant, as it is wholly available as part of NCOD - Round 1 &2 (source 137).
This source meets retrievability criteria because it is in tabular format.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
University of Akron Chemical Database
216
This database allows the user to retreive information for any of 23,495 hazardous chemicals
or 'generic' entries based on a keyword search. Potential keywords include names, formula
and registry numbers (CAS, DOT, RTECS, EINECS, Beilstein, Merck and EPA). Formula are
represented in Hill format for searching and a more descriptive format for viewing.
This data base and the information it contains were independently compiled by the author
from a large number of sources, and the data included as well as the manner in which it is
presented have been independently chosen by the author to provide what is deemed to be
an academic publication. Among the published references available, particular mention
should be made of:
2000 Emergency Response Guidebook ERG2000, 2000
Hazardous Chemicals Data NFPA 49, PC-49-94, 1994
Canadian WHMIS - Workplace Hazardous Materials Information System
U.S.C.G CHRIS database
U.S. EPA Cameo database
NIOSH/OSHA exposure limit data
Manufacuturer/supplier MSDS sheets
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Various governmental registry lists
(description from website)
University of Akron
jkh@chemistry.uakron.edu
Formula, Structure, Description, Uses, CAS, Partition coefficient, Solubility in water, Melting
point, UN number, Hazard class, Packing Group
This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://ull.chemistrv.uakron.edu/erd/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
University of Maryland - Partial List of Acute Toxins/Partial List of
Teratogens
217
Has been combined with the University of Maryland - Partial List of Teratogens (Source
218).
The Partial List of Acute Toxins is an alphabetical compilation of chemical substances that
met the University of Maryland definition of an "Acute Toxin" for the purpose of the
University of Maryland Chemical Hygiene Plan.
Acute toxins are defined as substances that have a median lethal dose (LD50) less than or
equal to 50 mg/kg body weight by the oral route of entry; 200 mg/kg body weight by the
dermal route of entry or a median lethal concentration (LC50) less than or equal to 0.5 mg/l
where time of exposure is eight hours or less. This definition is compatible with the 1994
Department of Transportation definition of "Poison."
This list is intended for use by University of Maryland laboratory personnel as an aid in
determining substances for which "designated use areas" will be required under the
University of Maryland Chemical Hygiene Plan. It is important to remember that this list is
not comprehensive. It does not include all acute toxins and does not list teratogens,
mutagens or select carcinogens. Additional lists may be accessed from the same INFORM
menu for other chemical hazard classifications to assist chemical hazard identification.
(description from website)
University of Maryland
University of Maryland Department of Environmental Safety (DES) Industrial Hygiene
division (301)405-3960
Name
This source is considered relevant for the CCL Universe because it contains a list of
chemicals with known toxicity/health effects.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
https://des. umd.edu/chemlists/acute.cfm
Data Source Name
University of Minnesota Biocatalysis & Biodegradation Database
(UM-BBD)
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Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
215
UM-BBD contains information on microbial biocatalytic reactions and biodegradation
pathways for primarily xenobiotic chemical compounds. The database contains lists of 861
compounds, 915 reactions, 140 pathways, 583 enzymes, 332 microorganisms, and 50
organic functional groups, (description from website)
Maintained by the University of Minnesota, with support from the International Scientific
Advisory Board
Users can contact UM-BBD using the form at the following location:
http://umbbd.ahc.umn.edu/contact.html
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.labmed.umn.edu/umbbd/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Unregulated Contaminant Information System (URCIS)
219
URCIS contains actual monitoring results (i.e., parametric data) from drinking water PWSs
used to support occurrence analyses for various OGWDW projects. URCIS generally
covered the Round 1 unregulated contaminant monitoring period (1983-1992). Extensive
data "clean-up" was necessary to resolve data quality issues within the various data sets.
These data quality issues, as well as the current status of the data sets, are described in
Occurrence of Unregulated Contaminants in Public Water Systems: An Initial Assessment
(EPA, 2001; EPA 815-P-00-001).
The Cadmus Group, Inc.; EPA OGWDW
Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
T: 617-673-7000
F: 617-673-7001
Drinking Water Occurrence Concentrations
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is redundant, as it was converted into NCOD Round 1 database, so URCIS is no
longer needed.
This source meets retrievability criteria because it is in tabular format.
Error! Hyperlink reference not valid.
Data Source Name
Identification Number
Data Source Description
US Army Center for Health Promotion and Medicine Detailed
Chemical Fact Sheets
220
Chemical fact sheets containing information on the physical properties and toxic properties
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
of weaponry agents.
U.S. Army Center for Health Promotion and Medicine
Users can request information using the form at the following website: http://chppm-
www.apgea.army.mil/contactusAA/email.asp
Chemical Formula, Description, Overexposure Effects, Reactivity Data, Toxicity Values,
Exposure Limits
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://chppm-www.apqea.armv.mil/dts/dtchemfs.htm
Data Source Name
Identification Number
Data Source Description
US EPA Civil Enforcement Docket
273
The DOCKET database contains information on all civil judicial cases filed by the
Department of Justice on behalf of the US Environmental Protection Agency and is the
official EPA database for tracking and reporting information on civil judicial and
administrative enforcement cases under all environmental statutes. The database is
maintained by EPA within the Office of Enforcement and Compliance Assurance (OECA).
Data entry is performed in each EPA Region and Headquarters. Records can be retrieved
for a site by using the facility or company name, address, EPA ID number, case
information, or dates.
Users can search by chemical or other name, chemical name fragment, Chemical Abstracts
Service Registry Number (RN), and/or subject terms. Search results can easily be viewed,
emailed, printed or downloaded.
Information Available:
Information tracked in DOCKET covers four broad areas:
1) Basic civil judicial and administrative enforcement case information: Law(s) and section(s)
violated, Facility information, Defendants/PRPs/Respondents, Penalty/cost recovery data,
Case attorney(s)/Technical contacts;
2) Descriptive text information: Case summary that provides a description of the case,
Status comments that describe case progress; 3) Case development milestones: Case
dates to track progression as the case moves form the Region, to DOJ, to court, then to
EPA Identification Number
Proprietor
Type of Data Elements
Relevance Explanation
conclusion; 4) Case conclusion information: Final disposition of case,
Penalty and cost recovery data, Compliance with consent instrument, Supplemental
environmental projects,
Injunctive relief, Environmental justice data
SUBJECT COVE RAGE:
Facility Location Data
Court Docket Number
File and Conclusion Dates
Case Names
Disposition
Violation Laws, Sections, and Types
Penalties and Recoveries
Pollutants
Defendant Information
(description from website)
National Information Services Corporation (NISC)
Case Number, Violated Law & Section, Violation Type, Date Filed, Date Concluded, Docket
Number, Assessed Fedral Penalty, Disposition of Case, Defendants, EPAID, Facility Name,
Street, City, State, ZIP
This source does not meet relevance criteria because it consists of text abstracts on
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.nisc.com/cis/details/DOCKET.HTM
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Victorian Infectious Diseases Reference Laboratory (VIDRL)
221
The Victorian Infectious Diseases Reference Laboratory (VIDRL) is a Victorian public health
reference laboratory with core responsibilities in virology and mycobacteriology. VIDRL also
provides expertise in bacteriology, parasitology, epidemiology and molecular detection
technologies, (description from website)
Victorian Infectious Diseases Reference Laboratory (Australia)
Victorian Infectious Diseases Reference Laboratory
10 Wreckyn St, North Melbourne
Victoria, Australia, 3051
Phone: (613)93422600
Facsimile: (613) 9342 2666 or (613) 9342 2660
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.vidrl.org.au/contact/contact.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Voluntary Cosmetic Registration Program Database (VCRP)
222
The Voluntary Cosmetic Registration Program (VCRP) is a voluntary data collection effort
initiated by the FDA that maintains information on cosmetic ingredients and reports of
cosmetic-related injuries. Since the FDA lacks authority to require manufacturers to register
their cosmetic establishments, only companies that wish to participate in the program
forward data to the FDA. Registered manufacturers or distributors are notified by the FDA if
a cosmetic ingredient may be harmful, (description from website)
FDA - Center for Food Safety and Applied Nutrition; Program maintained by FDA's Office of
Cosmetics and Colors; established at the request of cosmetic industry
Mary V. Waleski
Chief, Cosmetics Programs & Regulation Branch
HFS-106
Food and Drug Administration
5100 Paint Branch Parkway
College Park, MD 20740-3835
Phone:(202)418-3414
Fax: (202) 208-6937
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
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Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://vm.cfsan.fda.aov/~dms/cos-regn.html
Data Source Name
Identification Number
Data Source Description
Wastelnfo - AEA Technology
223
Wastelnfo is a comprehensive collection of references to international literature on non-
nuclear waste management and associated issues. The file covers the technical, policy, and
economic aspects of the subject, as well as all aspects of the waste management hierarchy:
minimization, recovery, recycling, treatment and disposal.
References are selected from journals, conferences, books, reports, legislative documents,
theses and patents. Because waste management is a multidisciplinary subject, a wide array
of journals from a variety of fields are covered, as well as the literature from the waste
management and environmental fields, (description from website)
Proprietor
Contact Information
Type of Data Elements
AEA Technology
Manager, Waste Management Information Bureau
AEA Technology Environment
F6Culham, OX143ED
United Kingdom
Telephone:+44 1235 463162
Fax: +441235463004
E-Mail: wmib@aeat.co.uk
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://librarv.dialoa.com/bluesheets/html/bl0110.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Water Environment Research Foundation (WERF) Microsheets
228
WERF Microsheets is a valuable database on waterborne microorganisms and emerging
pathogens and is available to WERF subscribers through a cooperative agreement with UK
Water Industry Research. The database provides information on occurrence, detection,
treatment, and other facts about microorganisms, (description from website)
UK Water Industry Research & Wrc-NSF Ltd.
WERF
635 Slaters Lane, Suite 300
Alexandria VA 22314
Telephone: (703) 684-2470
Fax: (703) 299-0742
Email: werf@werf.org
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Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
http://www.werf.ora/Products/tools.cfm
Data Source Name
Water Environment Research Foundation (WERF) Toxicity
Datasheets
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
229
WERF Datasheets is a valuable database on contaminant substances and is available to
WERF subscribers through a cooperative agreement with UK Water Industry Research. The
database provides information on occurrence, detection, treatment, and other facts about
contaminant substances, (description from website)
UK Water Industry Research & Wrc-NSF Ltd.
WERF
635 Slaters Lane, Suite 300
Alexandria VA 22314
Telephone: (703) 684-2470
Fax: (703) 299-0742
Email: werf@werf.org
Unknown
This source is considered relevant for the CCL Universe because it could be a source of
information on health effects.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because it is only available through a
subscription.
Data Source Name
Identification Number
Data Source Description
Water Resources Abstracts - Cambridge Scientific Abstracts
224
Water Resources Abstracts provide summaries of the world's technical and scientific
literature on water-related topics covering the characteristics, conservation, control, pollution,
treatment, use and management of water resources. Abstracts are drawn from journals,
books, conference proceedings, and technical reports in the physical and life sciences, as
well as from engineering, legal and government publications.
Until 1994, the database was produced by the United States Geological Survey, when it was
generally known as Selected Water Resources Abstracts. Since that time, Water Resources
Abstracts has been produced by Cambridge Scientific Abstracts, which broadened the scope
by including more material published outside the U.S. This database, which concentrates on
water supply and water treatment, complements the Aquatic Sciences & Fisheries Abstracts
database, ASFA, where there is greater coverage of the marine environment and biological
material.
Subscribers to Water Resources Abstracts on the Internet Database Service have free
access to Water Resources Netsites. This is a special service providing links to other
bibliographic databases, research and development programs, data sets, lists of experts and
researchers, conference and meetings information, and other resources on the Internet.
These sites have been carefully selected and evaluated by Cambridge Scientific Abstracts
editors who are all subject experts in their field, (description from website)
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Proprietor
Contact Information
Cambridge Scientific Abstracts
Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.csa.com/csa/ids/databases-collections.shtml - environmental
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Water Resources Worldwide
225
Water Resources Worldwide provides four of the world's major water-resource databases
plus powerful searching using the WATERLIT thesaurus. South Africa's WATERLIT,
Canada's AQUAREF, CAB Abstract's Aquatic Subset and the Netherlands' DELFT HYDRO
provide more than 607,790 citations and abstracts - oceans of vital water-research
information. Automated thesaurus based searching helps you find any topic with ease.
(description from website)
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com
Data Source Name
Identification Number
Data Source Description
WATERLIT
236
NISC produces WATERLIT, which has more than 366,480 references to industrial and
environmental aspects of water, wastewater and sanitation. Coverage of Africa is excellent,
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as is the analysis of water in arid lands, engineering projects, water quality, water treatment
and international water-related topics. Records are drawn from reports, conference
proceedings and over 760 journals from across the globe. The information dates from 1975
to the present day and about 12,000 new entries are added each year, (description from
website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
National Information Services Corporation (NISC)
National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It does not meet considerations because there was no documentation on how the data were
obtained.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.nisc.com/factsheets/gwrw.asp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
WATERNET - American Waterworks Association
226
WATERNET provides a comprehensive index of the publications of the American Water
Works Association and the AWWA Research Foundation. Included are books and
proceedings, journals, newsletters, standards, manuals, handbooks, and water quality
standard test methods. Emphasis is on the technical reports and studies from water utilities,
regulatory agencies, and research groups in the United States and its territories, Canada,
Mexico, and Latin America. European and Asian data are also reported. The database is the
online counterpart to the index to the Journal AWWA from 1971 to the present, and all
AWWA and AWWARF publications from 1973 to the present, with non-AWWA materials
included on a selective basis, (description from website)
American Water Works Association
American Water Works Association
Information Services Department
6666 W. Quincy Avenue
Denver, CO 80235
Telephone: 303-794-7711
Telex: 450895 AWWA DVR
Fax:303-794-7310
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://librarv.dialoq.com/bluesheets/htmlaa/bl0245.html
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Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Weekly Epidemiological Record (WER)
227
The Weekly Epidemiological Record (WER) is a weekly newsletter published by the World
Health Organization (WHO), intended to keep health professionals informed of international
epidemiological information, particularly concerning outbreaks and emerging infectious
diseases, (description from website)
World Health Organization
World Health Organization
Marketing and Dissemination
20 Avenue Appia, CH-1211 Geneva 27
Fax: (+4122)791 4857
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.who.int/wer/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
WHO Guidelines for Drinking Water Quality: Chemical Aspects:
Index of Chemicals
85
The assessment of the toxicity of drinking-water contaminants has been made on the basis
of published reports from the open literature, information submitted by governments and
other interested parties, and unpublished proprietary data. In the development of the
guideline values, existing international approaches to developing guidelines were carefully
considered. Previous risk assessments developed by the International Programme on
Chemical Safety (IPCS) in Environmental Health Criteria monographs, the International
Agency for Research on Cancer (IARC), the Joint FAO/WHO Meetings on Pesticide
Residues (JMPR), and the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
were reviewed. These assessments were relied upon except where new information justified a
reassessment. The quality of new data was critically evaluated prior to their use in risk
assessment, (description from website)
World Health Organization
WHO Headquarters
Avenue Appia 20
1211 Geneva 27
Switzerland
Telephone: (+41 22)791 21 11
Facsimile (fax): (+ 41 22) 791 3111
Telex: 415 416
Telegraph: UNISANTE GENEVA
email: info@who.int or library@who.int
Name, synonym, formula, MP, BP, density, VP, water solubility, Log Kow, odor thresholds,
use, environmental fate, ADI, CR, GV, IARC cancer class, TDI, NO(A)EL, LO(A)EL, LDx,
HRL, reproductive, embryotoxicity, teratogenicity, mutagenicity
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
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Source URL
http://www.who.int/docstore/water sanitation health/GDWQ/Chemicals/chemaspects.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
WHO Guidelines for Drinking Water Quality: Summary Tables
86
The tables provide a summary of guideline values for approximately 143 microorganisms
and chemicals in drinking-water extracted from the Guidelines for drinking-water quality, 2nd
ed. Vol. 2 Health criteria and other supporting information, 1996 (pp. 940-949) and Addendum
to Vol. 2 . 1998 (pp. 281-283). Example data elements include Consumer Complaint Level,
Guideline value, Remarks, and Screening value. Guideline values are provided for the
following types of contaminants: Microbiological, Inorganic, Organic, and Radioactive
constituents, Pesticides, Disinfectants and disinfectant by-products, Chemicals not of
health significance at concentrations normally found in drinking-water constituents, and
Substances that may give rise to complaints from consumers.
Additional summary information not included in the tables is provided for inorganic and
organic constituents, pesticides, chemicals not of considerable health significance, and
substances leading to complaints from consumers. These summaries provide background
data on the derivation of the guideline values, and may include an IARC assessment of
carcinogenicity, estimated dietary intake, NOAEL, LOAEL, Tolerable Daily Intake (TDI),
Provisional Maximum Tolerable Daily Intake (PMTDI), and reported concentrations of
contaminant in drinking water. The summary information varies for individual contaminants.
(description from website)
World Health Organization
WHO Headquarters
Avenue Appia 20
1211 Geneva 27
Switzerland
Telephone: (+41 22)791 21 11
Facsimile (fax): (+ 41 22) 791 3111
Telex: 415 416
Telegraph: UNISANTE GENEVA
email: info@who.int or library@who.int
Name, GV, TDI, basis
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.who.int/docstore/water sanitation health/GDWQ/Summarv tables/Sumtab.htm
Data Source Name
Identification Number
WHO Recommended Classification of Pesticides by Hazard (CPH)
40
Data Source Description
Pesticide Data Sheets (PDSs) - contain basic information for safe use of pesticides. The
Pesticide Data Sheets are prepared by WHO in collaboration with FAO and give basic
toxicological information on individual pesticides. Priority for issue of PDSs is given to
substances having a wide use in public health programmes and/or in agriculture, or having a
high or an unusual toxicity record. The data sheets are prepared by scientific experts and
peer reviewed. The comments of industry are provided through the industrial association,
GIFAP. The data sheets are revised from time to time as required.
The WHO Recommended Classification of Pesticides by Hazard was approved by the 28th
World Health Assembly in 1975 and has since gained wide acceptance. When it was
published in the WHO Chronicle, 29, 397-401 (1975), an annex, which was not part of the
Classification, illustrated its use by listing examples of classification of some pesticidal
active ingredients and their formulations. Later suggestions were made by Member States
and pesticide registration authorities that further guidance should be given on the
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retriev'ability Explanation
Source URL
classification of individual pesticides. Guidelines were first issued in 1978, and have since
been revised and reissued at 2-yearly intervals.
The document is arranged as follows:
Part I: The Classification as recommended by the World Health Assembly. This part is not
subject to periodic review and the classification table and text can only be changed by
resolution of the World Health Assembly.
Part II: Guidelines to Classification. Individual products are classified in a series of tables,
according to the oral or dermal toxicity of the technical product, and its physical state. The
tables are subject to review periodically.
The toxicity values are intended to be a guide only. Formulations should be separately
classified using the methods set out on pages 3 (single technical product) and 6 (mixtures)
and the table in Part I. To assist in the classification of formulations, an annex is now
provided giving numerical tables from which the classification may also be derived.
(description from website)
International Programme for Chemical Safety, World Health Organization, International
Labour Organisation, United Nations Environment Programme
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Dose, Critical Effect, BMC, BMD, ENEV, Cancer Group, TC(A), CTV, ECx, ICx, LCx, LDx,
LO(A)EL, NO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because, with the exception of the
classifications, it is not formatted for automated retrieval.
http://www.inchem.org/documents/pds/pdsother/class.pdf
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
World Health Organization - Information Products Catalogue
230
This Information Products Catalogue provides information on WHO publications produced
since 1948. Its search facility connects the user with information and links the user to the
list of health-related subjects in which WHO publishes, new publications, catalogues and
brochures available online, subscriptions to WHO publications. Links to ordering information,
to the network of WHO sales agents and WHO depository libraries and to the WHO web site
are also provided, (description from website)
World Health Organization
World Health Organization
Marketing and Dissemination
1211 Geneva 27, Switzerland
bookorders@who.int
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.who.int/dsa/cat98/chemtox8.htm
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