United States
Environmental Protection
Agency
Contaminant Candidate List 3
Microbes: Screening to the PCCL
Office of Water (4607M) EPA 815-R-08-006 February 2008 - Draft www.epa.gov/safewater
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Contents
Abbreviations and Acronyms 2
1.0 Background and Scope 3
2.0 Recommendations for Screening a Universe of Drinking Water Contaminants to Produce
a PCCL 3
3.0 Definition of Screening Criteria and Rationale for Their Application 4
3.1 Application of Screening Criteria to the Microbial CCL Universe 8
4.0 Additional Screening Criteria Considered 9
4.1 Organism Covered by Existing Regulations 9
5.0 Data Sources Used for Screening the Microbial CCL 3 Universe 11
6.0 Summary 12
7.0 References 13
Attachment A: Screening to the PCCL Al
Exhibits
Exhibit 1. Summary of Screening of Microbial CCL 3 Universe 8
Abbreviations and Acronyms
AWWA - American Water Works Association
AWWARF - American Water Works Association Research Foundation
CCL - Contaminant Candidate List
CCL 1 - EPA's First Contaminant Candidate List
CCL 2 - EPA's Second Contaminant Candidate List
CCL 3 - EPA's Third Contaminant Candidate List
MCLG - Maximum Contaminant Level Goal
NDWAC - National Drinking Water Advisory Council
NRC - National Research Council
NPDWR - National Primary Drinking Water Regulation
SDWA - Safe Drinking Water Act
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Contaminant Candidate List 3 Microbes: Screening to the PCCL
1.0 Background and Scope
The document titled, CCL 3 Microbes: Identifying the Universe (USEPA, 2007) provides
a summary of the statutory and regulatory background leading to development of a microbial
Contaminant Candidate List (CCL) and the subsequent activities to develop a microbial CCL 3
universe as the initial step in a transparent and scientifically sound Contaminant Candidate List
Classification Process (CCLCP).
This document summarizes criteria that the Environmental Protection Agency (EPA)
uses for screening a universe of microbiological contaminants to identify those contaminants in
the microbial CCL 3 universe to be placed on a Preliminary Contaminant Candidate List
(PCCL). These criteria were developed in part following the recommendations of the National
Research Council (NRC), the National Drinking Water Advisory Council (NDWAC) workgroup
on the CCL process. The recommended screening process was reviewed by a panel of external
experts, and the screening process described herein was derived from the subsequent
deliberations of the EPA microbiology workgroup based upon the expert panel report.
2.0 Recommendations for Screening a Universe of Drinking Water Contaminants to
Produce a PCCL
The NRC recommendations for a CCLCP are described in, Classifying Drinking Water
Contaminants for Regulatory Consideration (NRC, 2001). The NRC workgroup identified a
hierarchical framework for evaluating the potential occurrence of microbial contaminants in
drinking water. This approach suggested that EPA could obtain data on microbial contaminant
occurrence from existing occurrence databases and lists. Microbes with demonstrated or
potential occurrence in drinking water, and microbes with demonstrated or potential ability to
cause adverse health effects from drinking water exposure were recommended for inclusion in a
PCCL.
The NRC workgroup report did not contain specific recommendations for selection and
screening of microbial contaminants to a PCCL, and because occurrence data are not readily
available to support the screening process envisioned by the NRC workgroup, the Agency
requested further study of these issues by a workgroup convened by the NDWAC. NDWAC
recommended selecting microbial contaminants for a PCCL based upon an assessment of
occurrence attributes and health effects attributes relating to the plausibility of pathogen
presence, survival, and transport through drinking water resulting in disease manifestations from
drinking water exposure. These recommendations are described further in, National Drinking
Water Advisory Council Report on the CCL Classification Process (NDWAC, 2004).
The microbial CCL 3 universe was defined by the NDWAC workgroup as microbes that
are known to cause disease in humans. A literature review identified a list of 1,415 known
human pathogens including bacterial, viral, protozoan, helminth, and fungal pathogens (Taylor et
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al., 2001). The Taylor list was recommended as the basis of the microbial CCL 3 universe. EPA
requested nominations from the scientific community for additions to the microbial CCL 3
universe, and four microbes were added to the list through the nomination process (USEPA,
2006). EPA also added 6 fungi that did not appear on the list of Taylor et al. (2001) but were
identified in drinking water distribution systems. EPA also added one virus that was identified as
an emerging pathogen of potential interest, thus bringing the total number of microbes in the
CCL 3 universe to 1,425 pathogens.
Selection of microbes from the CCL 3 Universe for placement on the PCCL is based
upon screening criteria that assess the potential of water-related transmission (occurrence) and
the plausibility of causing waterborne disease by ingestion, inhalation, or dermal contact (health
effects). NDWAC recommended ten screening criteria for initial screening of pathogens in the
microbial CCL universe for placement on a PCCL. NDWAC also suggested that supplementing
these screening criteria may be necessary to insure that microbes on a PCCL represent only those
pathogens whose occurrence and health effects are attributable to drinking water. The principles
supporting supplemental screening criteria include:
• biological characteristics related to occurrence and survival
• taxonomic consolidations of genera or species by designating a representative
genus/species, i.e. allowing the designated type species of a pathogen to represent the
genus for screening purposes
• reliance upon epidemiological data to determine potential of adverse health effects
attributable to a drinking water source
The NDWAC workgroup evaluated the possibility of using virulence factor activity
relationships (VFARs) as a means of identifying potential waterborne pathogens. The
workgroup concluded that additional studies were necessary before VFARs could be used to
screen microbes to a PCCL (NDWAC 2004).
EPA restricted the PCCL to pathogens that are known to be associated with source water,
and recreational water only if the water is also drinking water (e.g., swimming pools) are
considered as candidates for the PCCL. Screening criteria are used to exclude those pathogens
whose biological properties are incompatible with water transmission by ingestion, inhalation or
dermal contact, and those pathogens that are typically introduced from sources other than
drinking water.
3.0 Definition of Screening Criteria and Rationale for Their Application
Screening criteria were developed based upon epidemiology, geographical distribution,
and biological properties in the host and in the environment. Screening criteria recommended by
NDWAC, as amended by the EPA microbiology workgroup following external peer review, are
listed below. Only one criterion is needed to screen out a pathogen. All pathogens that are not
excluded under any screening criteria are moved to the PCCL. However, any pathogen
documented to cause disease transmitted through drinking water, regardless of the following
screening criteria, is considered for the PCCL.
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Criterion 1:
Anaerobes (microorganisms that cannot survive in oxygenated environments)
Anaerobes are microorganisms that cannot survive in the presence of oxygen (Murray et
al., 2007). Because of oxygen toxicity, they are unable to survive in the ambient water
environment, and they pose negligible threat to human health from drinking water exposure.
Examples of anaerobes that are screened out based on this screening criterion include members
of the bacterial genera Actinomyces, Bacteroides, Clostridium, Eubacterium, Fusobacterium, and
Prevotella, among others (Murray et al., 2007).
Criterion 2:
Fastidious or obligate intracellular pathogens (environmental survival in water implausible)
Fastidious or obligate intracellular pathogens rely upon their host to provide essential
nutrients and growth factors that are not present in the environment, hence these pathogens
cannot survive outside their hosts. Many fastidious or obligate intracellular pathogens have a
narrow temperature and pH range as a result of host adaptation, and they cannot survive the wide
range of temperatures and pH common in the ambient environment. Examples of fastidious or
obligate intracellular pathogens that are screened out include members of the genera
Chlamydophila, Mycoplasma, and Orientia (Murray et al., 2007). This criterion is applied only
to bacteria, since all viruses are obligate intracellular pathogens (Knipe and Howley, 2007).
Criterion 3:
Pathogens exclusively transmitted by direct or indirect contact with blood or body fluids
(including sexually transmitted diseases)
Some pathogens are transmitted by direct or indirect contact with blood or body fluids,
where fecal-oral transmission or transmission by aerosolized water is not observed (Mandel et al.
2005). Pathogens causing bloodborne diseases and sexually transmitted diseases are highly host
adapted, fastidious, and are usually not present in feces. They do not survive under
environmental conditions, and they are not transmitted by the fecal-oral route, either by direct
contact with feces or indirect contact with contaminated drinking water. Examples of pathogens
transmitted by blood or body fluids include the etiologic agents of gonorrhea and syphilis,
Chlamydia, herpes virus, human immunodeficiency virus, and hepatitis virus B, C, D and G
(Murray et al., 2007).
Criterion 4:
Pathogens transmitted by vectors
Vectors include arthropods and rodents (Acha and Szyfres, 2001). Pathogens transmitted
by vectors depend upon either insect or other bites, or close contact with rodents, and these
pathogens are not transmitted by contact with drinking water. Mosquitoes, ticks, and fleas are the
most common vectors of arthropod-borne diseases (Krauss, et al., 2003). Examples of vector-
borne pathogens include bacteria, viruses, protozoa, and helminths. The genera Babesia,
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Borrelia, Brugia, Dirofilaria, Ehrlichia, Leishmania, Plasmodium, Trypanosoma, Rickettsia, and
all arthropod-borne viruses were not moved to the PCCL (Murray et al., 2007).
Criterion 5:
Microflora indigenous to the gastrointestinal tract, skin and mucous membranes
The human body is colonized with a rich and commensal microflora (Finegold et al.,
1983; Drasar and Barrrow, 1985; Isenberg and D'Amato, 1995). Some microbes that colonize
the human body are transitory, while others are part of the continuing normal flora of the body.
Microbes comprising normal flora have a characteristic ecological niche, but sometimes
conditions permit their access to areas of the body where they may exhibit pathogenic potential
resulting in infection and disease. Infections with normally innocuous microbes are called
opportunistic infections, because of their ability to exploit host conditions that may periodically
predispose them to disease. Because exposure to normal flora microbes is continuous throughout
life, and because the populations of normal flora microbes exceed the number of these microbes
present in drinking water by many orders of magnitude, drinking water represents an improbable
source of infection and disease. Examples of normal flora include members of the genera
Capnocytophaga, Corynebacterium, Staphylococcus, Streptococcus, and several yeasts (Murray
et al., 2007).
Criterion 6:
Pathogens transmitted solely by respiratory secretions
Pathogens causing respiratory disease are typically transmitted by direct contact with
respiratory secretions, either by inhalation of aerosols, by direct person-to-person contact, or by
contact with fomites. Drinking water is an unlikely mode of transmission because the number of
pathogens in respiratory secretions and the continuity of exposure to respiratory secretions far
exceed exposure through drinking water (Bennet and Brachman, 1998). Examples of pathogens
transmitted by respiratory secretions include the etiologic agents of tuberculosis, diphtheria,
whooping cough, measles, rubella, and influenza (Knipe and Howley, 2007; Murray et al., 2007;
Mandel et al., 2005).
Criterion 7:
Pathogens whose life cycle is incompatible with drinking water transmission
Some pathogens such as helminths, require intermediate hosts to complete their life
cycles, and incidental infection of humans results in an interruption of their life cycle with
subsequent death of the pathogen (Acha and Szyfres, 2001). Some pathogens are adapted to a
single route of transmission such as rabies virus, which is transmitted by animal bites. Some
pathogens are specifically adapted to survive in a unique ecological niche, and they cannot
withstand any alteration of conditions to which they are adapted. For example, rabies virus,
Dientamoebafragilis, Enterobius vermicularis, and many helminths remain in the microbial
CCL 3 universe and are not considered for the PCCL based on this criterion (Murray et al., 2007;
Ashford and Crewe, 2003).
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Criterion 8:
Pathogens where drinking water-related transmission is not implicated
Some pathogens cause such rare occurrences of disease that only a few cases have been
reported in medical literature, and these rare occurrences of disease present limited opportunity
to protect public health from drinking water exposure (Acha and Szyfres, 2001; Knipe and
Howley, 2007; Murray et al., 2007; Mandel et al., 2005). Some pathogens are associated with
direct transmission from animals to humans, or other transmission routes that do not involve
drinking water (Acha and Szyfres, 2001; Krauss et al, 2003; Howard, 2003). Examples of
pathogens that remain in the microbial CCL 3 universe after application of this criterion are
Leptospira, Listeria, Nosema, and the etiologic agents of several zoonotic virus infections
(Knipe and Howley, 2007; Murray et al., 2007).
Criterion 9
Natural habitat is in the environment without epidemiological evidence of drinking water-related
disease
The environment is teeming with microorganisms, at varying concentrations, and humans
are in constant contact with these microorganisms throughout their lives (Bennett and Brachman,
1998; Isenberg and D'Amato, 1995). Microorganisms naturally present in the environment are
not considered a threat to public health as a result of drinking water exposure unless
epidemiological evidence demonstrates a potential for water-related disease. Thus, outbreaks
occurring in nosocomial settings or attributable to recreational water resulting from post-delivery
contamination of drinking water are not sufficient to place a microorganism on the PCCL unless
the drinking water system was shown to be contaminated (Wenzel, 2003). Acinetobacter,
Gordonia, Nocardia, Pseudomonas, and most fungi are excluded from the PCCL based on this
criterion (Murray et al., 2007; Howard, 2003).
Criterion 10
Pathogens not endemic to North America
Some pathogens have an exclusive geographical distribution, and they are not naturally
present in North America (Ashford and Crewe, 2003; Murray et al., 2007; Palmer et al., 1998).
Only pathogens endemic to North America have the potential to contaminate drinking water in
the U.S. Several helminths such as most Diphyllobothrium, and Paragonimus species and several
viruses such as the hemorrhagic fever viruses and poxviruses would remain in the microbial
CCL universe after application of this criterion.
Criterion 11
A genus and species or serotype may be chosen to represent a group of closely related organisms
EPA has chosen a few pathogens to represent a group based on all serotypes within a
group sharing essential biological properties in common with the group. Designation of a
representative group provides adequate protection of public health under the CCLCP (Murray et
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al., 2007). Pathogens that represent other pathogens in their group are the following: Arcobacter
butzleri, Campylobacter jejuni, Helicobacter pylori, Legionella pneumophila, Salmonella
enterica, Shigella sonnet, y4denovirus, Astrovirus, Enterovirus, Microsporidia, and Entamoeba
histolytica.
Criterion 12
Current taxonomy does not support the classification listed by Taylor et al. (2001).
Microbial taxonomy and nomenclature is a dynamic science, and taxonomic
classifications are constantly changing. Original taxonomic classifications were based upon the
phenotypic characteristics of microorganisms, but these classifications are being revised as
genotypic information becomes available. New genera are formed, sometimes prematurely,
based upon partial genomic data, and taxonomists do not always agree with proposed changes.
Under this criterion, the genera Fluoribacter and Tatlockia are combined with the genus
Legionella for screening purposes (Murray et al., 2007).
3.1 Application of Screening Criteria to the Microbial CCL Universe
Bacteria, viruses, protozoa, helminths, and fungi in the CCL 3 Universe are shown
respectively in the tables of Attachment A, and CCL 3 Microbes: Indentifying the Universe.
Each table identifies the pathogens in each category and indicates which screening criteria were
applied to remove pathogens from further consideration in the CCL Process. Those pathogens
not excluded by at least 1 of the 10 screening criteria or consolidated under criteria 11 or 12 pass
on to the PCCL. The summary data from the screening is shown in Exhibit 1.
Exhibit 1. Summary of Screening Microbial CCL 3 Universe
Pathogen
Class
Bacteria
Viruses
Protozoa1
Helminths
Fungi
Total
Total
540
219
66
287
313
1,425
Screening Criteria
1
125
0
0
0
0
125
2
14
0
0
0
0
14
3
10
26
1
0
0
37
4
37
99
29
25
0
190
5
117
0
3
0
13
133
6
7
17
0
0
1
25
7
0
1
4
107
0
112
8
29
16
7
0
0
52
9
154
0
7
0
309
470
10
2
45
0
155
0
202
11
28
8
6
0
0
42
12
5
0
0
0
0
5
On
PCCL
12
7
7
0
3
29
^ryptosporidium and Giardia are considered to be regulated by LT2. They were not screened and were not
considered for CCL3.
Based upon this screening exercise conducted on 1,425 pathogens in the microbial CCL
universe 1,394 pathogens were excluded from consideration while 29 pathogens passed to the
PCCL. The specific screening decisions and references are presented in Attachment A.
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4.0 Additional Screening Criteria Considered
As the CCL3 process developed, EPA considered screening criteria in addition to the
twelve described above. While each of these additional criteria had merit, they were not
consistent with the ultimate goal of the CCL3. The goal of the CCL is to identify potential
contaminants that may require regulation. The basis for regulating specific contaminants is:
• Occurrence at a level and frequency that presents a potential public health risk, and
• The feasibility and opportunity for achieving meaningful reduction of exposure from
such contaminants.
Listing contaminants on the CCL identifies the need for collecting additional information to
inform the basis for potential regulations, and if that threshold of information is met, to support
new regulation or revisions to existing regulations to control or improve control for such
contaminants. If contaminants are not listed on a CCL (e.g., CCL 3), EPA may include those
contaminants as occurrence and health effects information becomes available in a future listing.
The following subsections present additional screening criteria that EPA considered but elected
not to use at this time.
4.1 Organism Covered by Existing Regulations
4.1.1 Organisms Covered by Fecal Indicator Monitoring
EPA considered a screening criterion based upon contaminants that might be controlled
through drinking water monitoring requirements under current drinking water regulations. Many
of the bacteria in the CCL Universe, including the Enterobacteriaceae and members of the
genera Campylobacter and Vibrio, are associated with fecal contamination and as such their
presence could be signaled by the monitoring requirements under the Total Coliform Rule
(TCR). Under the TCR, EPA chose to require monitoring for Escherichia coli (and total
coliforms) in finished drinking water because it provides a broad indication of the potential
presence of fecal pathogens in drinking water, though more so for bacteria than for viruses and
protozoa.
EPA chose not to exclude common enteric bacterial pathogens from the PCCL even
though they may be indicated by the TCR. Numerous waterborne disease outbreaks have
occurred in systems that were in compliance with maximum contaminant limit (MCL) drinking
water monitoring requirements under the TCR. EPA recognizes that monitoring under the TCR
(i.e., monitoring for total coliforms andE. coli or fecal coliforms when total coliforms are
present, (Oldstadt, et al., 2007)) may not always be protective against bacterial fecal
contamination. The frequency of total coliform monitoring under the TCR is limited, especially
for smaller systems, thus transitory fecal contamination could go undetected. EPA believes that
enteric pathogens should be included for further regulatory consideration in the CCL because
monitoring under the TCR may be too limited to protect against specific types of bacterial fecal
contamination.
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4.1.2 Organisms Covered by Treatment Technique
According to the Safe Drinking Water Act (SDWA), EPA must select contaminants that
"at the time of publication, are not subject to any proposed or promulgated national primary
drinking water regulation..." In promulgating regulations for drinking water contaminants, EPA
can set either a legal limit (MCL) and require monitoring for the contaminant in drinking water
or EPA can establish a treatment technique requirement.
The Surface Water Treatment Rule (SWTR) included maximum contaminant level goals
(MCLGs), for Legionella, Giardia, and viruses of zero because any amount of exposure to these
contaminants represents some public health risk. Since measuring disease-causing microbes in
drinking water is not considered to be feasible, EPA established a treatment technique
requirement for these contaminants. The purpose of subsequent treatment technique
requirements (Interim Enhanced Surface Water Treatment Rule, Long Term Surface Water
Treatment Rule 1 and Long Term Surface Water Treatment Rule 2), which included an MCLG
of zero for Cryptosporidium, is to reduce disease incidence associated with Cryptosporidium and
other pathogenic microorganisms in drinking water. Therefore, they are excluded from the
PCCL. Cryptosporidium and Giardia have a substantial amount of associated research regarding
health effects and sensitivity to various treatment control measures.
The Ground Water Rule (GWR) sets treatment technique requirements to control for
viruses (and pathogenic bacteria), because it was not feasible to directly monitor for viruses (or
pathogenic bacteria) in drinking water. Under the GWR, if systems detect total coliforms in the
distribution system, they are required to monitor for a fecal indicator (E. coli, coliphage, or
enterococci) in the source water. If fecal contamination is found in the source water, the system
must take remedial action to address contamination.
EPA did not exclude specific viruses and Legionella from the PCCL even though they
have broad category MCLGs and treatment technique requirements. Viruses and Legionella
include a wide range of taxa for which EPA has much less information concerning health effects
and treatment information. The available information for different viral taxa (e.g., dose response
and treatment data) was very limited when setting the treatment technique requirements for
surface water and ground water systems. Also, different viral taxa have been implicated in
various waterborne disease outbreaks in distribution systems. EPA did not have viral dose
response or treatment data at the time of promulgating the treatment technique requirements.
Legionella has been recognized as occurring in public water systems and has been recently
implicated in numerous waterborne disease outbreaks (WBDOs) in distribution.
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5.0 Data Sources Used for Screening the Microbial CCL 3 Universe
Various data sources were used to gather the information for this screening process. The
data sources used were evaluated by EPA to ensure they were authoritative and appropriate. For
microbes, the universe list was defined as all known human pathogens using the compilation of
Taylor et al. (2001) as a practical starting point. This list was supplemented by adding fungi
isolated from drinking water distribution systems that did not appear on the Taylor list, and by
nominations from the scientific community, as described earlier in this report (see also CCL 3
Microbes: Identifying the Universe, EPA, 2007). For microbes, the data sources were sought to
develop the information needed for screening (and later scoring) for the pathogens in the defined
CCL 3 Microbial Universe.
The hierarchy of text-based resource materials begins with recently compiled
authoritative reference books such as The Manual of Clinical Microbiology, 9th Edition, and
Field's Virology, 5th Edition, both published in 2007. Both of these two-volume reference books
have become established as the leading authoritative reference sources in their respective fields,
both references have evolved through multiple editions, and both publications are considered
reference standards to the scientific community for their scope and depth of coverage. They are
edited by world-recognized authorities, and chapters are written by an international team of
subject experts. The parasites of Homo sapiens, second edition, is a comprehensive source for
information on the helminthes. These and other compiled sources listed in the reference list
below were used to provide the information for screening the pathogens in the microbial CCL 3
Universe.
Primary publications were used to supplement compiled sources as necessary to support
screening decisions for the fungi that were added to the CCL 3 Microbial Universe. However,
some pathogens in the CCL 3 Microbial Universe were unusual or obscure, and were not
covered in the compiled or primary sources. They required alternative sources, and these
pathogens were searched for individually, using Web searches of authoritative on-line sources.
Web references were used to find information for screening rarely encountered viruses,
protozoa, and fungi, primarily for information related to Criterion 9, "natural habitat in the
environment," or Criterion 10, "pathogen not endemic to North America". Selected Web
references were evaluated to ensure that the site sponsors possessed the expertise to
authoritatively address the issues of habitat and geographical distribution of the pathogen in
question, and that the information was presented objectively and reviewed by members of the
scientific community. Emphasis was placed upon Web sites sponsored and supported by
government agencies or academic institutions, with evidence of peer review, such as an editorial
board and/or expert contributors and reviewers.
Attachment A, The CCL 3 Microbial Universe List, tabulates the screening decisions for
the CCL 3 Microbial Universe, and shows the screening reference used to support the decision.
Page ranges cited and Web addresses/links provided are as narrow and specific as they can be, to
identify the information related to the screening criterion used. Many pathogens could be
screened by several criteria, however only one criterion is noted in the tabulation. Understanding
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the complete context and rationale for a screening decision often requires a review of the
complete chapter from which the specified page range was taken.
6.0 Summary
Properly designed screening criteria will restrict the microbial PCCL to human pathogens
that may cause drinking water-related diseases from ingestion, inhalation, or dermal contact.
Pathogens failing to meet these criteria will remain in the microbial universe until
epidemiological surveillance data or nomination processes support their reevaluation.
Ten screening criteria and two consolidation criteria have been proposed for selection of
pathogens in the microbial CCL3 universe to a PCCL. Application of these twelve criteria to the
microbial CCL3 universe results in a PCCL containing 29 pathogens
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7.0 References
Acha, P. N. and B. Szyfres (ed.). 2001. Zoonoses and Communicable Diseases Common to Man
and Animals. Volume I, Bacterioses and Mycoses. Scientific and Technical Publication No. 580.
Pan American Health Organization. Washington D.C., USA.
Ashford, R. W. and W. Crewe. 2003. The parasites of Homo sapiens: An annotated checklist of
the protozoa, helminths and arthropods for which we are home. Taylor and Francis, London, UK.
Bennett, J. V. And P. S. Brachman (ed.). 1998. Hospital infections. Lippincott-Raven,
Philadelphia, PA.
Doggett, M. S. 2000. Characterization of fungal biofilms within a municipal water distribution
systems. Applied and Environmental Microbiology 66:1249-1251.
Drasar, B. S., and P. A. Barrow. 1985. Intestinal Microbiology, Vol. 10. Van Nostrand Reinhold,
Berkshire.
Finegold, S. M., S. V. L., and G. E. Mathisen. 1983. Normal Indigenous Intestinal Flora, p. 3-31.
In D. J. Hentges (ed.), Human Intestinal Microflora in Health and Disease. Academic Press, New
York.
Howard, D. H. (ed.) 2003. Pathogenic fungi in humans and animals, 2nd Edition. Marcel Dekker,
Inc., New York, NY.
Isenberg, H. D. and R. F. D'Amato. 1995. Indigenous and Pathogenic Microorganisms of
Humans. In Murray, P. R., E. J. Baron, M. A. Pfaller, F. C. Tenover, and R. H. Yolken, ed.
Manual of Clinical Microbiology, 6th ed. ASM Press, Washington, DC.
Knipe, D. M. and P. M. Howley (ed.). 2007. Fields Virology, 5th Edition, Wolters-Kluwer
Lippincott Williams & Williams, Philadelphia.
Kolafova, Libuse, 2007. Schistosomes causing cercarial dermatitis: a mini-review of current
trends in systematics and of host specificity and pathogenicity. Folia Parasitologica 54: 81-87,
2007.
Krauss, H., A. Weber, M. Appel, B. Enders, H. D. Isenberg, H. G. Schiefer, W. Slenczka, A. von
Graevenitz, and H. Zahner. 2003. Zoonoses, Infectious Diseases Transmissible from Animals to
Humans, 3rd. Edition. ASM Press, Washington, DC.
Mandel, G. L., J. E. Bennett, and R. Dolin (ed.). 2005. Douglas and Bennett's Principles and
Practice of Infectious Diseases, 6th Edition, Elsevier, Philadelphia.
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Murray, P. R., E. J. Baron, J. H. Jorgensen, M. L. Landry, and M. A. Pfaller (ed.). 2007. Manual
of Clinical Microbiology, 9th Edition, ASM Press, Washington, DC.
National Research Council (NRC). 2001. Classifying Drinking Water Contaminants for
Regulatory Consideration. National Academy Press, Washington DC.
National Drinking Water Advisory Council (NDWAC). 2004. National Drinking Water
Advisory Council Report on the CCL Classification Process to the U. S. Environmental
Protection Agency, May 19, 2004
Olstadt, J., J. Schauer, J. Standridge and S. Kluender. 2007. A comparison often USEPA
approved total coliform/E. coli tests. Journal of Water and Health, 05.2:267 - 282.
Palmer, S. R., Lord Soulsby, and D. I. H. Simpson (ed.). 1998. Zoonoses: biology, clinical
practice, and public health control. Oxford University Press, Oxford, UK.
Patterson, Thomas F. 2005. Advances and challenges in management of invasive
Mycoses. Lancet 2005; 366: 1013-25.
Rosenzweig, W. H. Minnigh and W. Pipes. 1986. Fungi in Potable Water Systems. Research
and Technology; AWWA:53. January 1986.
Taylor, L. H., S. M. Latham, and M. E. Woolhouse. 2001. Risk factors for human disease
emergence Philosophical Transactions of the Royal Society of London B. Vol. 356, pp. 983-989
(See electronic Appendix A, No. 1411, pp. 1-9).
United States Environmental Protection Agency (USEPA). 2006. Request for nominations of
drinking water contaminants for the contaminant candidate list. Federal Register 71(199):60704-
60708.
United States Environmental Protection Service (USEPA). 2007. Contaminant Candidate List 3
Microbes: Identifying the Universe.
Wenzel, R. P. (ed.). 2003. Prevention and control of nosocomial infections. Lippincott Williams
& Wilkins, Philadelphia, PA.
West, P. R. 1986. Isolation rates and characterization of fungi in drinking water distribution
systems. Proceedings of the Water Quality Technology Conference, American Water Works
Association, Denver, CO.
14
-------
EPA-OGWDW CCL 3 Microbes: EPA 815-R-08-006
Screening to the PCCL February 2008 - DRAFT
Attachment A: Screening to the PCCL
Al
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Abiotrophia defective
Achromobacter piechaudii
Achromobacter xylosoxidans
Acidaminococcus fermentans
Acinetobacter baumannii
Acinetobacter calcoaceticus
Acinetobacter haemolyticus
Acinetobacter johnsonii
Acinetobacter junii
Acinetobacter Iwoffii
Acinetobacter radioresistens
Actinobacillus equuli
Actinobacillus hominis
Actinobacillus lignieresii
Actinobacillus pleuropneumoniae
Actinobacillus suis
Actinobacillus ureae
Actinomyces georgiae
Actinomyces gerencseriae
Actinomyces israelii
Actinomyces meyeri
Actinomyces naeslundii
Actinomyces neuii
Actinomyces odontolyticus
Actinomyces radingae
Actinomyces turicensis
Aerococcus viridans
Aeromonas caviae
Aeromonas hydrophila
Aeromonas sobria
Aeromonas veronii
Alcaligenes odorans
Amycolatopsis orientalis
Arcanobacterium bernardiae
Arcanobacterium heamolyticum
Arcanobacterium pyogenes
Arcobacter butzleri
Arcobacter cryaerophilus
Bacillus anthracis
Bacillus cereus
Bacillus circulans
Bacillus coagulans
Bacillus licheniformis
Bacillus mycoides
Bacillus pumilus
Bacillus sphaericus
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
X
X
X
X
2
3
X
X
X
X
X
4
5
X
X
X
X
X
X
6
7
8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11
X
12
PCCL
Aeromonas hydrophila
Arcobacter butzleri
Page Reference
MCM-9, p. 445
MCM-9, p. 777
MCM-9, p. 777
MCM-9, p. 862-863
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 771-773
MCM-9, p. 621-623
MCM-9, p. 621-623
MCM-9, p. 621-623
MCM-9, p. 621-623
MCM-9, p. 621-623
MCM-9, p. 621-623
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 445
MCM-9, p. 716-717
MCM-9, p. 716-717
MCM-9, p. 716-717
MCM-9, p. 777
MCM-9, p. 520
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 935
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 455-456
A2
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Bacillus subtilis
Bacillus thuringiensis
Bacteroides caccae
Bacteroides distasonis
Bacteroides eggerthii
Bacteroides forsythus
Bacteroides fragilis
Bacteroides galacturonicus
Bacteroides merdae
Bacteroides ovatus
Bacteroides pectinophilus
Bacteroides splanchnicus
Bacteroides stercoris
Bacteroides thetaiotaomicron
Bacteroides uniformis
Bacteroides ureolyticus
Bacteroides vulgatus
Bartonella bacilliformis
Bartonella elizabethae
Bartonella henselae
Bartonella quintana
Bergeyella zoohelcum
Bifidobacterium dentium
Bilophila wadsworthia
Bordetella avium
Bordetella bronchiseptica
Bordetella parapertussis
Bordetella pertussis
Borrelia brasiliensis
Borrelia burgdorferi
Borrelia caucasica
Borrelia crocidurae
Borrelia duttonii
Borrelia hermsii
Borrelia hispanica
Borrelia latyschewii
Borrelia mazzottii
Borrelia parkeri
Borrelia persica
Borrelia recurrentis
Borrelia turicatae
Borrelia venezuelensis
Brevibacillus brevis
Brevundimonas diminuta
Brevundimonas vesicularis
Brucella melitensis
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
2
X
3
4
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
5
X
6
X
X
X
X
7
8
9
X
X
X
X
X
10
11
12
PCCL
Page Reference
MCM-9, p. 455-456
MCM-9, p. 455-456
MCM-9, p. 91 1
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 850-851
MCM-9, p. 850-851
MCM-9, p. 850-851
MCM-9, p. 850-851
MCM-9, p. 793
MCM-9, p. 872-873
MCM-9, p. 911
MCM-9, p. 803
MCM-9, p. 803
MCM-9, p. 803
MCM-9, p. 803
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 972-973
MCM-9, p. 455, 458
MCM-9, p. 750-751
MCM-9, p. 750-751
MCM-9, p. 825
A3
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Burkholderia cepacia
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter coli
Campylobacter concisus
Campylobacter curvus
Campylobacter fetus
Campylobacter gracilis
Campylobacter hyointestinalis
Campylobacter lari
Campylobacter rectus
Campylobacter sputorum
Campylobacter upsaliensis
Capnocytophaga canimorsus
Capnocytophaga cynodegmi
Capnocytophaga gingivalis
Capnocytophaga ochracea
Capnocytophaga sputigena
Cardiobacterium hominis
Cedecea davisae
Cedecea lapagei
Cedecea neteri
Cellulomonas cellulans
Cellulomonas turbata
Centipeda periodontii
Chlamydia trachomatis
Chlamydophila pneumoniae
Chlamydophila psittaci
Chromobacterium violaceum
Chryseobacterium balustinum
Chryseobacterium meningosepticum
Citrobacter amalonaticus
Citrobacter braakii
Citrobacter farmeri
Citrobacter freundii
Citrobacter koseri
Citrobacter rodentium
Citrobacter sedlakii
Citrobacter werkmanii
Citrobacter youngae
Clostridium baratii
Clostridium bifermentans
Clostridium botulinum
Clostridium butyricum
Clostridium chauvoei
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
2
X
X
3
X
4
5
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
6
7
8
X
X
X
X
X
9
X
X
X
X
X
X
X
X
X
10
X
11
X
X
12
PCCL
Campylobacter jejuni
Page Reference
MCM-9, p. 750-751
MCM-9, p. 752
MCM-9, p. 752
MCM-9, p. 934-935
MCM-9, p. 933-934
MCM-9, p. 933-934
MCM-9, p. 934-935
MCM-9, p. 933-934
MCM-9, p. 934-935
MCM-9, p. 935
MCM-9, p. 933-934
MCM-9, p. 934-935
MCM-9, p. 934-935
MCM-9, p. 621 , 629
MCM-9, p. 621 , 629
MCM-9, p. 621 , 629
MCM-9, p. 621 , 629
MCM-9, p. 621 , 629
MCM-9, p. 621 , 628-629
MCM-9, p. 702, 704
MCM-9, p. 702, 704
MCM-9, p. 702, 704
MCM-9, p. 489-490, 506
MCM-9, p. 489-490, 506
MCM-9, p. 911
MCM-9, p. 1021
MCM-9, p. 1021
MCM-9, p. 1021
MCM-9, p. 621 , 624-625
MCM-9, p. 791-792
MCM-9, p. 791-792
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 699, 703
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
A4
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Clostridium difficile
Clostridium fallax
Clostridium histolyticum
Clostridium novyi
Clostridium perfringens
Clostridium ramosum
Clostridium septicum
Clostridium sordellii
Clostridium sporogenes
Clostridium tertium
Clostridium tetani
Collinsella aerofaciens
Comamonas testosteroni
Corynebacterium afermentans
Corynebacterium argentoratense
Corynebacterium bovis
Corynebacterium diphtheriae
Corynebacterium jeikeium
Corynebacterium kutscheri
Corynebacterium macginleyi
Corynebacterium minutissimum
Corynebacterium propinquum
Corynebacterium pseudodiphthericum
Corynebacterium pseudotuberculosis
Corynebacterium striatum
Corynebacterium ulcerans
Corynebacterium urealyticum
Corynebacterium xerosis
Coxiella burnetii
Delftia acidovorans
Dermatophilus congolensis
Dichelobacter nodosus
Edwardsiella hoshinae
Edwardsiella tarda
Eggerthella lenta
Ehrlichia chaffeensis
Ehrlichia equi
Ehrlichia ewingii
Ehrlichia phagocytophila
Ehrlichia sennetsu
Eikenella corrodens
Enterobacter aerogenes
Enterobacter amnigenus
Enterobacter asburiae
Enterobacter cancerogenus
Enterobacter cloacae
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
X
X
X
X
X
X
X
X
2
X
3
4
X
X
X
X
X
5
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
6
X
7
8
9
X
X
X
X
X
X
X
X
X
X
10
11
12
PCCL
Page Reference
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 889
MCM-9, p. 873, 875
MCM-9, p. 750-751
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-491
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 489-490
MCM-9, p. 1062-1063
MCM-9, p. 750-751
MCM-9, p. 520
MCM-8, p. 880-881
MCM-9, p. 702-704
MCM-9, p. 702-704
MCM-9, p. 872-873
MCM-9, p. 1046-1049
MCM-9, p. 1046-1049
MCM-9, p. 1046-1049
MCM-9, p. 1046-1049
MCM-9, p. 1046-1049
MCM-9, p. 621 , 625
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
A5
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Entembacter gergoviae
Entembacter hormaechei
Entembacter sakazakii
Enterococcus avium
Enterococcus casseliflavus
Enterococcus durans
Enterococcus faecalis
Enterococcus faecium
Enterococcus flavescens
Enterococcus gallinarum
Enterococcus hirae
Enterococcus mundtii
Enterococcus raffinosus
Erysipelothrix rhusiopathiae
Escherichia coli
Eubacterium brachy
Eubacterium combesii
Eubacterium contortum
Eubacterium cylindroides
Eubacterium limosum
Eubacterium moniliforme
Eubacterium multiforme
Eubacterium nodatum
Eubacterium rectale
Eubacterium saburreum
Eubacterium saphenum
Eubacterium sulci
Eubacterium tenue
Eubacterium timidum
Ewingella americana
Fibrobacter intestinalis
Filifactor alocis
Finegoldia magna
Fluoribacter bozemanae
Fluoribacter dumoffii
Fluoribacter gormanii
Francisella tularensis
Fusobacterium mortiferum
Fusobacterium necrophorum
Fusobacterium nucleatum
Fusobacterium periodonticum
Fusobacterium ulcerans
Fusobacterium varium
Gardnerella vaginalis
Gemella morbillorum
Gordonia amarae
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
2
3
4
X
5
X
X
X
6
7
8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11
12
X
X
X
PCCL
Escherichia coli
Page Reference
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 431-432
MCM-9, p. 480
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 702-704
MCM-8, p. 880-881
MCM-9, p. 872-874
MCM-9, p. 862-863
MCM-9, p. 835
MCM-9, p. 835
MCM-9, p. 835
MCM-9, p. 816-817
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 508
MCM-9, p. 445
MCM-9, p. 520
A6
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Gordonia bronchialis
Gordonia rubropertincta
Gordonia sputi
Gordonia terrae
Granulicatella adiacens
Haemophilusactinomycetemcomitans
Haemophilus aphrophilus
Haemophilus ducreyi
Haemophilus haemolyticus
Haemophilus influenzae
Haemophilus parahaemolyticus
Haemophilus parainfluenzae
Haemophilus paraphrophilus
Haemophilus segnis
Hafnia alvei
Helicobacter cinaedi
Helicobacter fennelliae
Helicobacter heilmannii
Helicobacter pullorum
Helicobacter pylori
Kingella denitrificans
Kingella kingae
Klebsiella granulomatis
Klebsiella ornithinolytica
Klebsiella oxytoca
Klebsiella pneumoniae
Kluyvera ascorbata
Kluyvera cryocrescens
Lactobacillus sp.
Legionella anisa
Legionella birminghamensis
Legionella cherrii
Legionella cincinnatiensis
Legionella feeleii
Legionella hackeliae
Legionella jordanis
Legionella lansingensis
Legionella longbeachae
Legionella oakridgensis
Legionella pneumophila
Legionella rubrilucens
Legionella sainthelensi
Legionella tucsonensis
Legionella wadsworthii
Leifsonia aquatica
Leptospira borgpetersenii
Screening Criteria Used for Exclusion
1
X
2
3
X
4
5
X
X
X
X
X
X
X
X
X
X
X
6
7
8
X
9
X
X
X
X
X
X
X
X
X
X
X
X
10
11
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
12
PCCL
Helicobacter pyori
Legionella pneumophila
Page Reference
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 445
MCM-9, p. 623, 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 636-637
MCM-9, p. 699
MCM-9, p. 949-950
MCM-9, p. 949-950
MCM-9, p. 949-950
MCM-9, p. 949-950
MCM-9, p. 621 , 625
MCM-9, p. 621 , 625
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 699, 702
MCM-9, p. 702-704
MCM-9, p. 702-704
MCM-9, p. 872-873
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 836
MCM-9, p. 485, 489
MCM-9, p. 963-965
A7
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Leptospira inadai
Leptospira intermgans
Leptospira kirschneri
Leptospira meyeri
Leptospira noguchii
Leptospira santarosai
Leptospira weilii
Leptotrichia buccalis
Lister! a ivanovii
Listeria monocytogenes
Listeria seeligeri
Listeria welshimeri
Mannheimia haemolytica
Megamonas hypermegale
Megasphaera sp.
Methylobacterium mesophilicum *
Methylobacterium zatmanii*
Micromonas micros
Moraxella atlantae
Moraxella bovis
Moraxella catarrhalis
Moraxella caviae
Moraxella cuniculi
Moraxella lacunata
Moraxella lincolnii
Moraxella liquefaciens
Moraxella nonliquefaciens
Moraxella osloensis
Moraxella ovis
Morganella morganii
Mycobacterium abscessus
Mycobacterium africanum
Mycobacterium asiaticum
Mycobacterium avium
Mycobacterium bovis
Mycobacterium celatum
Mycobacterium chelonae
Mycobacterium conspicuum
Mycobacterium fortuitum
Mycobacterium genavense
Mycobacterium gordonae
Mycobacterium haemophilum
Mycobacterium kansasii
Mycobacterium leprae
Mycobacterium malmoense
Mycobacterium marinum
Screening Criteria Used for Exclusion
1
X
X
X
X
2
X
X
3
4
5
X
X
X
X
X
X
X
X
X
X
X
X
X
6
7
8
X
X
X
X
X
X
X
X
X
X
X
X
X
9
X
X
X
X
X
X
X
X
X
X
X
X
10
X
11
12
PCCL
Mycobacterium avium
Page Reference
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 963-965
MCM-9, p. 911
MCM-9, p. 474
MCM-9, p. 474
MCM-9, p. 474
MCM-9, p. 474
MCM-9, p. 621-622
MCM-9, p. 913
MCM-9, p. 862
MCM-9, p. 789
MCM-9, p. 789
MCM-9, p. 487
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 774-775
MCM-9, p. 700, 703
MCM9, p. 544
MCM-9, p. 546
MCM-9, p. 544, 549
MCM-9, p. 544
MCM-9, p. 544, 549
MCM9, p. 544
MCM9, p. 544
MCM9, p. 544
MCM9, p. 544
MCM-9, p. 544, 549-50
MCM9, p. 544
MCM9, p. 544
MCM-9, p. 544
MCM-9, p. 544, 548
MCM-9, p. 544, 548
A8
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Mycobacterium mucogenicum
Mycobacterium peregrinum
Mycobacterium porcinum
Mycobacterium scrofulaceum
Mycobacterium senegalense
Mycobacterium shimoidei
Mycobacterium simiae
Mycobacterium smegmatis
Mycobacterium szulgai
Mycobacterium tuberculosis
Mycobacterium ulcerans
Mycobacterium xenopi
Mycoplasma fermentans
Mycoplasma genitalium
Mycoplasma hominis
Mycoplasma pneumoniae
Mycoplasma salivarium
Myroides odoratus
Neisseria cinerea
Neisseria elongate
Neisseria flava
Neisseria flavescens
Neisseria gonorrhoeae
Neisseria lactamica
Neisseria meningitidis
Neisseria mucosa
Neisseria perflava
Neisseria sicca
Neisseria subflava
Neisseria weaver!
Nocardia asteroides
Nocardia brasiliensis
Nocardia caviae
Nocardia farcinica
Nocardia nova
Nocardia otitidiscaviarum
Nocardia pseudobrasiliensis
Nocardia transvalensis
Ochrobactrum anthropi
Oligella ureolytica
Oligella urethralis
Orientia tsutsugamushi
Paenibacillus alvei
Paenibacillus macerans
Pantoea agglomerans
Pasteurella aerogenes
Screening Criteria Used for Exclusion
1
2
X
X
X
X
X
X
3
X
4
5
X
X
X
X
X
X
X
X
X
X
X
X
X
6
X
X
7
8
X
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11
12
PCCL
Page Reference
MCM9, p. 544
MCM9, p. 544
MCM9, p. 544
MCM-9, p. 544, 550
MCM9, p. 544
MCM-9, p. 544, 550
MCM-9, p. 544, 548
MCM9, p. 544
MCM-9, p. 544, 548
MCM-9, p. 544-546
MCM-9, p. 544, 549
MCM-9, p. 544, 549
MCM-9, p. 1004-1007
MCM-9, p. 1004-1007
MCM-9, p. 1004-1007
MCM-9, p. 1004-1007
MCM-9, p. 1004-1007
MCM-9, p. 780-781
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 601
MCM-9, p. 616
MCM-9, p. 601-602
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 616
MCM-9, p. 602
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 784
MCM-9, p. 775
MCM-9, p. 775
MCM-9, p. 1036-1037
MCM-9, p. 455, 458
MCM-9, p. 455, 458
MCM-9, p. 700
MCM-9, p. 621-622
A9
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Pasteurella caballi
Pasteurella canis
Pasteurella dagmatis
Pasteurella multocida
Pasteurella pneumotropica
Pasteurella stomatis
Peptococcus niger
Peptostreptococcus anaerobius
Peptostreptococcus asaccharolyticus
Peptostreptococcus lactolyticus
Peptostreptococcus prevotii
Peptostreptococcus vaginalis
Photobacterium damselae
Plesiomonas shigelloides
Porphyromonas asaccharolytica
Porphyromonas catoniae
Porphyromonas circumdentaria
Porphyromonas endodontalis
Porphyromonas gingivalis
Porphyromonas levii
Porphyromonas macacae
Prevotella bivia
Prevotella buccae
Prevotella buccalis
Prevotella corporis
Prevotella dentalis
Prevotella denticola
Prevotella disiens
Prevotella enoeca
Prevotella heparinolytica
Prevotella intermedia
Prevotella loescheii
Prevotella melaninogenica
Prevotella nigrescens
Prevotella oralis
Prevotella oris
Prevotella oulora
Prevotella ruminicola
Prevotella tannerae
Prevotella veroralis
Prevotella zoogleoformans
Propionibacterium acnes
Propionibacterium avidum
Propionibacterium granulosum
Propionibacterium propionicus
Proteus mirabilis
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
2
3
4
5
X
X
X
X
X
X
6
7
8
9
X
X
10
11
12
PCCL
Plesiomonas shigelloides
Page Reference
MCM-9, p. 621-622
MCM-9, p. 621-622
MCM-9, p. 621-622
MCM-9, p. 621-622
MCM-9, p. 621-622
MCM-9, p. 621-622
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 723, 725
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 872-873
MCM-9, p. 700, 703
A10
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Proteus penneri
Proteus vulgaris
Providencia alcalifaciens
Providencia rettgeri
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas alcaligenes
Pseudomonas fluorescens
Pseudomonas pseudoalcaligenes
Pseudomonas putida
Pseudomonas stutzeri
Pseudonocardia autotrophica
Pseudoramibacter alactolyticus
Psychrobacter phenylpyruvicus
Rahnella aquatilis
Ralstonia pickettii
Rhodococcus equi
Rhodococcus erythropolis
Rhodococcus fascians
Rhodococcus rhodnii
Rhodococcus rhodochrous
Rickettsia africae
Rickettsia akari
Rickettsia australis
Rickettsia conorii
Rickettsia felis
Rickettsia honei
Rickettsia japonica
Rickettsia massiliae
Rickettsia prowazekii
Rickettsia rickettsii
Rickettsia sibirica
Rickettsia typhi
Rothia dentocariosa
Ruminococcus productus
Saccharomonospora viridis
Saccharopolyspora rectivirgula
Salmonella bongori
Salmonella choleraesuis
Salmonella enteritidis
Salmonella typhi
Salmonella typhimurium
Sebaldella termitidis
Selenomonas artemidis
Selenomonas dianae
Selenomonas flueggei
Screening Criteria Used for Exclusion
1
X
X
X
X
X
X
2
3
4
X
X
X
X
X
X
X
X
X
X
X
X
5
X
6
7
8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11
X
X
X
X
12
PCCL
Salmonella enterica
Page Reference
MCM-9, p. 700, 703
MCM-9, p. 700, 703
MCM-9, p. 700, 703
MCM-9, p. 700, 703
MCM-9, p. 700, 703
MCM-9, p. 734-735
MCM-9, p. 734-735
MCM-9, p. 734-735
MCM-9, p. 734-735
MCM-9, p. 734-735
MCM-9, p. 734-735
MCM-9, p. 516, 519-520
MCM-9, p. 872-873
MCM-9, p. 774-775
MCM-9, p. 698-701
MCM-9, p. 750-751
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 1036-1037
MCM-9, p. 506
MCM-9, p. 862-863
MCM-9, p. 520, 526
MCM-9, p. 520, 526
MCM-9, p. 659-660, 679-670
MCM-9, p. 659-660, 679-670
MCM-9, p. 659-660, 679-670
MCM-9, p. 659-660, 679-670
MCM-8, p. 880-881
MCM-9, p. 911
MCM-9, p. 911
MCM-9, p. 911
A11
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Selenomonas infelix
Selenomonas noxia
Serratia ficaria
Serratia marcescens
Serratia odorifera
Serratia plymuthica
Serratia proteamaculans
Serratia rubidaea
Shigella boydii
Shigella dysenteriae
Shigella flexneri
Shigella sonnei
Sphingomonas paucimobilis
Spirillum minus
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus hyicus
Staphylococcus intermedius
Staphylococcus lugdunensis
Staphylococcus saprophyticus
Staphylococcus warneri
Stenotrophomonas maltophilia
Streptobacillus moniliformis
Streptococcus acidominimus
Streptococcus agalactiae
Streptococcus anginosus
Streptococcus bow's
Streptococcus canis
Streptococcus constellatus
Streptococcus criceti
Streptococcus equi
Streptococcus gordonii
Streptococcus intermedius
Streptococcus milleri
Streptococcus mitis
Streptococcus mutans
Streptococcus pneumoniae
Streptococcus pyogenes
Streptococcus salivarius
Streptococcus sanguis
Streptococcus sobrinus
Streptococcus suis
Streptococcus uberis
Sutterella wadsworthensis
Suttonella indologenes
Screening Criteria Used for Exclusion
1
X
X
X
2
X
3
X
4
5
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
6
7
8
9
X
X
X
X
X
X
X
X
10
11
X
X
X
12
PCCL
Shigella sonnei
Page Reference
MCM-9, p. 91 1
MCM-9, p. 91 1
MCM-9, p. 700, 702
MCM-9, p. 700, 702
MCM-9, p. 700, 702
MCM-9, p. 700, 702
MCM-9, p. 700, 702
MCM-9, p. 700, 702
MCM-9, p. 679
MCM-9, p. 678-679
MCM-9, p. 678-679
MCM-9, p. 786-787
MCM-9, p. 381-382
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 390, 392
MCM-9, p. 750-751
MCM-9, p. 621 , 631
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 414
MCM-9, p. 911
MCM-9, p. 621 , 629
A12
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Bacteria
Tatlockia maceachernii
Tatlockia micdadei
Tatumella ptyseos
Treponema carateum
Treponema pallidum
Tropheryma whippelii
Tsukamurella inchonensis
Tsukamurella paurometabola
Tsukamurella pulmonis
Tsukamurella tyrosinosolvens
Ureaplasma urealyticum
Veillonella atypica
Veillonella dispar
Veillonella parvula
Vibrio alginolyticus
Vibrio cholerae
Vibrio cincinnatiensis
Vibrio fluvialis
Vibrio furnissii
Vibrio hollisae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio vulnificus
Wolinella succinogenes
Yersinia bercovieri
Yersinia enterocolitica
Yersinia frederiksenii
Yersinia intermedia
Yersinia kristensenii
Yersinia mollaretii
Yersinia pestis
Yersinia pseudotuberculosis
Yersinia rohdei
Yersinia ruckeri
540 Bacteria
Screening Criteria Used for Exclusion
1
X
X
X
X
125
2
X
14
3
X
10
4
X
37
5
117
6
7
7
0
8
X
X
X
X
X
X
X
X
X
29
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
154
10
2
11
28
12
X
X
5
PCCL
Vibrio cholerae
Yersinia enterocolitica
PCCL =12
Page Reference
MCM-9, p. 835
MCM-9, p. 835
MCM-9, p. 701 , 704
MCM-9, p. 988
MCM-9, p. 988
MCM-9, p. 1070-1071
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 520
MCM-9, p. 1004-1007
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 862-863
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 723
MCM-9, p. 911
MCM-9, p. 688
MCM-9, p. 688
MCM-9, p. 688
MCM-9, p. 688
MCM-9, p. 688
MCM-9, p. 689
MCM-9, p. 689
MCM-9, p. 688
MCM-9, p. 688
The bacteria identified by an asterisk were added to the microbial CCL universe by EPA as a result of nominations from the scientific community.
A13
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Andes virus
Apoi virus
Australian bat lyssavirus
Bagaza virus
Bangui virus
Banna virus
Banzi virus
Barmah Forest virus
Batken virus
Bayou virus
Bebaru virus
Bhanja virus
BK virus
Black creek canal virus
Borna disease virus
Bovine Ephemeral Fever virus
Bovine Papular Stomatitis virus
Bovine Spongiform Encephalopathy
(BSE) agent
Buffalopox virus
Bunyamwera virus
Bussuquara virus
Bwamba virus
California encephalitis virus
Candiru virus complex
Caraparu virus
Catu virus
Cercopithecine herpes virus 1
Chandipura virus
Changuinola virus
Chikungunya virus
Chim virus
Creutzfeld-Jokob Disease (CJD) agent
Colorado tick fever virus
Cote d'lvoire Ebola virus
Notes
Screening Criteria Used for Exclusion
1 I 2
3
X
X
_
4
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
5
6
X
7
8
X
X
X
9
10
X
X
X
11
12
PCCL
Reference
MCM-9, p. 1502
Field's Virology, 5th Ed., p. 1153-
1158,1206
Field's Virology, 5th Ed., p. 1364
Field's Virology, 5th Ed., p. 1153-
1158,1199
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/7t
hReport/sites/descriptions/Orthomv
xoviridae/t hoaotovirus.htm
MCM-9, p. 1501-1502
Field's Virology, 5th. Ed., p. 1024
MCM-9, p. 1486-1491
MCM-9, p. 1612-1613
MCM-9, p. 1501-1502
Field's Virology, 5th Ed., p. 1835
Field's Virology, 5th Ed., p. 1367
Field's Virology, 5th Ed., p. 2948,
2955-2956, 2963
MCM-9, p. 87-89
Field's Virology, 5th Ed. p. 2955-
2956
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 2895-
2897
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/IC
TVdB/1 1000000.htm
Field's Virology, 5th Ed., p. 443-
444, 3077-3078
MCM-9, p. 1486-1491
Field's Virology, 5th. Ed., p. 619,
1411-1412, 1432-1434
A14
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Cowpox virus
Crimea-Congo Haemorrhagic Fever
Virus
Dakar bat virus
Dengue virus
Dhori virus
Dobrava-Belgrade virus
Dug be virus
Duvenhage virus
Eastern equine encephalitis virus
Edge Hill virus
Encephalomyocarditis virus
European bat lyssavirus 1
European bat lyssavirus 2
European Tick-borne encephalitis
virus
Everglades virus
Eyach virus
Far eastern Tick-borne encephalitis
virus
Foot and mouth disease virus
Ganjam virus
Getah virus
Guama virus
Guanarito virus
Guaroa virus
Hantaan virus
Hendra virus
Hepatitis A virus
Hepatitis B virus
Hepatitis C virus
Hepatitis delta virus
Hepatitis E virus
Hepatitis G virus
HU39694 virus
Hughes virus
Human adenovirus A
Human adenovirus B
Human adenovirus C
Human adenovirus D
Notes
Screening Criteria Used for Exclusion
1 | 2
3
X
X
X
X
4
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
5
6
X
X
7
8
X
X
X
9
10
X
X
X
X
X
X
X
X
X
11
X
12
PCCL
Hepatitis A
Hepatitis E
Adenovirus
Reference
MCM-9, p. 1632
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1158,
1206
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1502
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1364
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 796,
840, 858-860
Field's Virology, 5th Ed., p. 1364
Field's Virology, 5th Ed., p. 1364
Field's Virology, 5th Ed., p. 1153-
1158, 1200-1203
MCM-9, p. 1486-1491
Krausset al., p. 87-89
Field's Virology, 5th Ed., p. 1153-
1158, 1200-1203
Field's Virology, 5th Ed., p. 796,
840, 858-860
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1024
MCM-9, p. 1486-1491
MCM-9, p. 1512
MCM-9, p. 1486-1491
MCM-9, p. 1502
MCM-9, p. 1478-1479
MCM-9, p. 1641, 1643-1644
MCM-9, p. 1437-1438
MCM-9, p. 1653
MCM-9, p. 1445-1447
http://www.cdc.gov/ncidod/disease
s/hanta/hps/noframes/phvs/ecoloav
.htm
Field's Virology, 5th Ed., p. 1743-
1745
MCM-9, p. 1589-1591
MCM-9, p. 1589-1591
MCM-9, p. 1589-1591
A15
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Human adenovirus E
Human adenovirus F
Human astrovirus
Human Coronavirus 229E
Human Coronavirus OC43
Human enterovirus 68
Human enterovirus 70
Human enterovirus A
Human enterovirus B
Human enterovirus C
Human enterovirus D
Human Herpesvirus 1
Human Herpesvirus 2
Human Herpesvirus 3
Human Herpesvirus 4
Human Herpesvirus 5
Human Herpesvirus 6
Human Herpesvirus 7
Human Herpesvirus 8
Human Immunodeficiency Virus 1
Human Immunodeficiency Virus 2
Human papillomavirus
Human parainfluenza virus 1
Human parainfluenza virus 2
Human parainfluenza virus 3
Human parainfluenza virus 4
Human parechovirus type 1
Human parechovirus type 2
Human Respiratory Syncytial virus
Human Rhinovirus A
Human Rhinovirus B
Human T-Lymphotropic Virus 1
Igbo-ora virus
llheus virus
Influenza A virus
Influenza B virus
Influenza C virus
Issyk-Kul virus
Japanese encephalitis virus
JC virus
Junin virus
Juquitiba virus
Notes
Human
enterovirus D
Human
enterovirus D
Screening Criteria Used for Exclusion
1 I 2
3
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
4
X
X
X
X
X
5
6
X
X
X
X
X
X
X
X
X
X
X
X
7
8
X
X
9
10
11
X
X
X
X
X
X
12
PCCL
Astrovirus
Enterovirus
Reference
MCM-9, p. 1589-1591
MCM-9, p. 1589-1591
MCM-9, p. 1414-1415
MCM-9, p. 1414-1415
MCM-9, p. 1392-1394
MCM-9, p. 1392-1394
MCM-9, p. 1392-1394
MCM-9, p. 1392-1394
MCM-9, p. 1392-1394
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1524
MCM-9, p. 1309-1310
MCM-9, p. 1309-1310
MCM-9, p. 1601
MCM-9, p. 1352
MCM-9, p. 1352
MCM-9, p. 1352
MCM-9, p. 1352
MCM-9, p. 1393-1394
MCM-9, p. 1393-1394
MCM-9, p. 1361-1362
MCM-9, p. 1405-1406
MCM-9, p. 1405-1406
MCM-9, p. 1330-1331
Field's Virology, 5th Ed., p. 1024,
1048
MCM-9, p. 1486-1491
MCM-9, p. 1340-1341
MCM-9, p. 1340-1341
MCM-9, p. 1340-1341
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1612-1613
MCM-9, p. 1512
Field's Virology, 5th Ed., p. 1743-
1745
A16
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Karshi virus
Kasokero virus
Kedougou virus
Kemerovo virus
Kokobera virus
Koutango virus
Kyasanur forest disease virus
Laguna Negra virus
Lanjan virus
Lassa virus
Lebombo virus
Lechiguanas virus
Louping ill virus
Lymphocytic choriomeningitis virus
Machupo virus
Madrid virus
Marburg virus
Marituba virus
Mayaro virus
Measles virus
Menangle virus
Mimivirus1
Mokola virus
Molluscum contagiosum virus
Monkeypox virus
Monongahela virus
Mucambo virus
Mumps virus
Murray Valley encephalitis virus
New York virus
Newcastle disease virus
Nipah virus
Norwalk-like viruses
Nyando virus
Ockelbo virus
Notes
Screening Criteria Used for Exclusion
1 | 2
3
X
X
X
4
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
5
6
X
X
7
8
X
X
9
10
X
X
X
X
X
X
X
11
12
PCCL
Calicivirus
Reference
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/IC
TVdB/1 1000000.htm
Field's Virology, 5th Ed., p. 1153-
1158,1199
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1502
http://phene.cpmc.columbia.edu/IC
TVdB/1 1000000.htm
MCM-9, p. 1512
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/7t
hReport/sites/descriptions/Bunvavir
idae/hantavirus.htm
MCM-9, p. 1486-1491
MCM-9, p. 1512
MCM-9, p. 1512
MCM-9, p. 1486-1491
MCM-9, p. 1512
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1378-1379
http://www.cdc.gov/ncidod/eid/vol4
no2/philbev htm
Field's Virology, 5th Ed., p. 627-
628, 637-638
Field's Virology, 5th Ed., p. 1363-
1364
MCM-9, p. 1631-1632
MCM-9, p. 1631-1632
http://phene.cpmc.columbia.edu/7t
hReport/sites/descriptions/Bunvavir
idae/hantavirus.htm
MCM-9, p. 1486-1491
MCM-9, p. 1352
MCM-9, p. 1486-1491
MCM-9, p. 1501-1502
Field's Virology, 5th Ed., p. 1497-
1498
MCM-9, p. 1478-1479
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
A17
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Omsk haemorrhagic fever virus
O'nyong-nyong virus
Oran virus
Orf virus
Oriboca virus
Oropouche virus
Orungo virus
Parvovirus B1 9
Phnom-Penh bat virus
Picobirnavirus
Piry virus
Poliovirus
Powassan virus
Pseudocowpox virus
Punta Toro virus
Puumala virus
Quaranfil Virus
Rabies virus
Reo virus
Reston Ebola virus
Rift Valley fever virus
Rio Bravo virus
Rocio virus
Ross River virus
Rotavirus A
Rotavirus B
Rotavirus C
Rotavirus D
Rotavirus E
Rotavirus F
Royal Farm virus
Rubella virus
Sabia virus
Saimiriine herpesvirus 1
Salehabad virus
Sandfly fever Naples virus
Notes
Human
enterovirus
Screening Criteria Used for Exclusion
1 | 2
3
X
4
X
X
*
X
X
X
X
X
X
X
X
X
X
X
X
5
6
X
X
7
X
8
X
X
X
X
X
X
9
10
X
X
X
X
X
X
X
X
X
11
X
12
PCCL
Rotavirus
Reference
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/7t
hReport/sites/descriptions/Bunvavir
idae/hantavirus.htm
MCM-9, p. 1631-1640
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1623
Field's Virology, 5th Ed., p. 1153-
1158, 1206
MCM-9, p. 1456-1457
MCM-9, p. 1486-1491
MCM-9, p. 1392-1394
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 2948,
2960, 2963
MCM-9, p. 1486-1491
MCM-9, p. 1502
MCM-9, p. 1486-1491
MCM-9, p. 1471
Field's Virology, 5th Ed., p. 1897-
1900
MCM-9, p. 1512
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1153-
1158, 1206
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1456-1457
MCM-9, p. 1456-1457
MCM-9, p. 1456-1457
MCM-9, p. 1456-1457
MCM-9, p. 1456-1457
Field's Virology, 5th Ed., p. 1153-
1158, 1204
MCM-9, p. 1384
MCM-9, p. 1512
Field's Virology, 4th Ed., p. 2383,
2483, 251 1 , 2848
http://phene.cpmc.columbia.edu/IC
TVdB/1 1041 008.htm
MCM-9, p. 1486-1491
A18
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Viruses
Sandfly fever virus group
Saumarez Reef virus
Sealpox virus
Semliki Forest virus
Seoul virus
Sepik virus
Sin Nombre virus
Sindbis virus
St. Louis encephalitis virus
Sudan Ebola virus
Suid herpesvirus
Swine vesicular disease virus
Tacaiuma virus
Tamdy virus
Tanapox virus
Tataguine virus
Thogoto virus
Trubanaman virus
Tyuleniy virus
Usutu virus
Variola virus
Venezuelan Equine Encephalitis virus
Vesicular stomatitis virus
Wad Medani virus
Wanowrie virus
Wesselsbron virus
West Nile virus
Western Equine Encephalitis virus
Wyeomyia virus
Yaba monkey tumor virus
Yellow fever virus
Yogue virus
Zaire Ebola virus
Zika virus
Zinga virus
21 9 Viruses
Notes
Vesicular
exanthema of
swine
Screening Criteria Used for Exclusion
1
2 3
0
-
X
0 | 26
456
X
X
X
X
X
X
_
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
104
0
19
7
1
8
X
X
18
9
0
10
X
X
X
X
X
X
X
X
36
11
8
12
0
PCCL
PCCL = 7
Reference
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1153-
1158,1206
MCM-9, p. 1632, 1634
MCM-9, p. 1486-1491
MCM-9, p. 1501-1502
MCM-9, p. 1486-1491
MCM-9, p. 1501-1502
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1512
Field's Virology, 4th Ed., p. 2385,
2484, 2707
Field's Virology, 5th Ed., p. 963
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1632, 1634
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1153-
1158, 1206
MCM-9, p. 1486-1491
MCM-9, p. 1631-1632
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
Field's Virology, 5th Ed., p. 1975-
1977
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1486-1491
MCM-9, p. 1632
MCM-9, p. 1486-1491
http://phene.cpmc.columbia.edu/IC
TVdB/1 1000000.htm
MCM-9, p. 1512
MCM-9, p. 1486-1491
http://www.cdc.aov/mmwr/preview/
mmwrhtm 1/00001 253.htm
1This virus-like agent was added to the microbial CCL universe by EPA as a result of nominations from the scientific community.
2This virus group was added to the microbial CCL universe by EPA.
A19
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Protozoa
Acanthamoeba astronyxis
Acanthamoeba castellani
Acanthamoeba culbertsoni
Acanthamoeba hatchetti
Acanthamoeba palestinensis
Acanthamoeba polyphaga
Acanthamoeba rhysoides
Babesia bovis
Babesia divergens
Babesia gibsoni
Babesia microti
Balamuthia mandrillaris
Balantidium coli
Blastocystis hominis
Cryptosporidium parvum 1
Cyclospora cayetanensis
Dientamoeba fragilis
Encephalitozoon cuniculi
Encephalitozoon hellem
Encephalitozoon intestinalis
Entamoeba chattoni
Entamoeba histolytica
Entamoeba moshkovskii
Enterocytozoon bieneusi
Giardia duodenalis 1
Isospora belli
Leishmania aethiopica
Leishmania amazonensis
Leishmania braziliensis
Leishmania chagasi
Leishmania donovani
Leishmania guyanensis
Leishmania infantum
Leishmania lainsoni
Leishmania major
Leishmania mexicana
Leishmania naiffi
Leishmania panamensis
Leishmania peruviana
Leishmania pifanoi
Leishmania shawi
Screening Criteria Used for Exclusion
1 I 2
3
4
X
X
X
X
5
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
6
7
8
X
X
9
X
X
X
X
X
X
X
X
10
11
=
X
X
X
X
X
12
PCCL
Blastocystis hominis
Cyclospora cayetanensis
Microsporidia
Entamoeba histolytica
Isospora belli
Reference
MCM-9, p. 2082
MCM-9, p. 2082-2084
MCM-9, p. 2082-2084
MCM-9, p. 2082
MCM-9, p. 2082, Krauss et al., p. 264-268
MCM-9, p. 2082
MCM-9, p. 2082
MCM-9, p. 2051
MCM-9, p. 2051
MCM-9, p. 2051
MCM-9, p. 2051
MCM-9, p. 2030, 2084
MCM-9, p. 2106-2107
MCM-9, p. 2103-2104
MCM-9 p. 2133-2135
MCM-9 p. 2133-2135
htto://www. ita.be/ita/DistanceLearnina/LectureNote
sVandenEndenE/06 Amoebiasisp2.htm#IX 450
htto://www. ita.be/ita/DistanceLearnina/LectureNote
sVandenEndenE/06 Amoebiasisp2.htm#IX 450
MCM-9 p. 2133-2135
MCM-9, p. 2057-2158
MCM-9, p. 2057-2158
MCM-9, p. 2057-2158
MCM-9, p. 2057-2158
MCM-9, p. 2057-2158
MCM-9, p. 2057-2158, Krauss et al., p. 282-284
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
A20
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Protozoa
Leishmania tropica
Leishmania venezuelensis
Naegleria fowleri
Nosema africanum
Nosema ceylonensis
Nosema connori
Nosema ocularum
Pentatrichomonas hominis
Plasmodium falciparum
Plasmodium knowlesi
Plasmodium malariae
Plasmodium ovale
Plasmodium simium
Plasmodium vivax
Retortamonas intestinalis
Sarcocystis hominis
Sarcocystis lindermanni
Sarcocystis suihominis
Toxoplasma gondii
Trachipleistophora hominis
Trichomonas tenax
Trichomonas vaginalis
Trypanosoma brucei
Trypanosoma cruzi
Vittaforma corneae
66 Protozoa
Screening Criteria Used for Exclusion
1 I 2
0 | 0
3
X
1
4
X
X
X
X
X
X
X
X
X
X
29
5
X
X
X
3
6
0
7
X
X
X
4
8
X
X
X
X
X
7
9
7
10
0
11
=
X
6
12
0
PCCL
Naegleria fowleri
Toxoplasma gondii
PCCL = 7
Reference
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9, p. 2133-2135, Palmer et al., p. 609
MCM-9, p. 2133-2135, Palmer et al., p. 609
MCM-9, p. 2133-2135, Palmer et al., p. 609
MCM-9, p. 2133-2135
MCM-9, p. 2093
MCM-9, p. 2040
MCM-9, p. 2040
MCM-9, p. 2040
MCM-9, p. 2040
MCM-9, p. 2040
MCM-9, p. 2040
MCM-9, p. 2093
MCM-9, p. 2114-2115
MCM-9, p. 2114-2115
MCM-9, p. 2114-2115
MCM-9 p. 2133-2134
MCM-9, p. 2032. 2034, 2093
MCM-9, p. 2104-2105
MCM-9, p. 2057-2058
MCM-9, p. 2057-2058
MCM-9 p. 2133-2134
Cryptosporidium and Giardia are considered to be regulated by the Long Term Surface Water Treatment Rule (LT-2). These organisms are not listed on CCL3.
A21
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Acanthocephalus rauschi
Achillurbainia nouveli
Achillurbainia recondite
Alaria americana
Alaria marcianae
Amphimerus pseudofelineus
Anatrichosoma cutaneum
Ancylostoma braziliense
Ancylostoma caninum
Ancylostoma ceylanicum
Ancylostoma duodenale
Ancylostoma malayanum
Anisakis physeteris
Anisakis simplex
Aonchotheca philippinensis
Apophallus donicus
Artyfechinostomum mehrai
Ascaris lumbricoides
Ascaris suum
Ascocotyle sp.
Australobilharzia terrigalensis
Baylisascaris procyonis
Bertiella mucronata
Bertiella studeri
Bilharziella polonica
Bolbosoma sp.
Brugia beaveri
Brugia guyanensis
Brugia malayi
Brugia pahangi
Brugia timori
Bunostomum phlebotomum
Calodium hepaticum
Carneocephallus brevicaea
Cathaemasia cabrerai
Centrocestus armatus
Centrocestus formosanus
Cheilospirura sp.
Clinostomum complanatum
Contracaecum osculatum
Corynosoma strumosum
Cryptocotyle lingua
Cyclodontostomum purvisi
Synonyms and Notes
Opisthorchis
quayaquilensis
Paracapillaria
philippinensis
Artyfechinostomum
malayanum
Phagicola longa
Screening Criteria Used for Exclusion
1|2|3
4
X
X
X
X
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Asford and Crewe, 2003, p. 93
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 50
Ashford and Crewe, 2003, p. 29
Ashford and Crewe, 2003, p. 30
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 88
Ashford and Crewe, 2003, p. 68
Ashford and Crewe, 2003, p. 69
Ashford and Crewe, 2003, p. 69
Ashford and Crewe, 2003, p. 69
Ashford and Crewe, 2003, p. 69
Ashford and Crewe, 2003, p.75
Ashford and Crewe, 2003, p. 75
Ashford and Crewe, 2003, p. 89
Ashford and Crewe, 2003, p. 40
Ashford and Crewe, 2003, p. 35
Ashford and Crewe, 2003, p. 76
Ashford and Crewe, 2003, p. 77
Ashford and Crewe, 2003, p. 44
Ashford and Crewe, 2003, p. 31
Ashford and Crewe, 2003, p. 77
Ashford and Crewe, 2003, p. 59
Ashford and Crewe, 2003, p. 59
Ashford and Crewe, 2003, p. 31
Ashford and Crewe, 2003, p. 93
Ashford and Crewe, 2003, p. 81
Ashford and Crewe, 2003, p. 81
Ashford and Crewe, 2003, p. 82
Ashford and Crewe, 2003, p. 82
Ashford and Crewe, 2003, p. 82
Ashford and Crewe, 2003, p. 112
Ashford and Crewe, 2003, p. 89
Ashford and Crewe, 2003, p. 47
Ashford and Crewe, 2003, p. 35
Ashford and Crewe, 2003, p. 40
Ashford and Crewe, 2003, p. 41
Ashford and Crewe, 2003. p. 81
Ashford and Crewe, 2003, p. 29
Ashford and Crewe, 2003, p. 76
Ashford and Crewe, 2003, p. 93
Ashford and Crewe, 2003, p. 41
Ashford and Crewe, 2003, p. 69
A22
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Dicmcoelium dendriticum
Dicmcoelium hospes
Dioctophyme renale
Dipetalonema arbuta
Dipetalonema reconditum
Diphyllobothrium cameroni
Diphyllobothrium cordatum
Diphyllobothrium dalliae
Diphyllobothrium dendriticum
Diphyllobothrium elegans
Diphyllobothrium erinaceieuropaei
Diphyllobothrium hians
Diphyllobothrium houghtoni
Diphyllobothrium klebanovskii
Diphyllobothrium lanceolatum
Diphyllobothrium latum
Diphyllobothrium mansonoides
Diphyllobothrium nihonkaiense
Diphyllobothrium orcini
Diphyllobothrium pacificum
Diphyllobothrium scoticum
Diphyllobothrium
stemmacephalum
Diphyllobothrium theileri
Diplogonoporus balaenopterae
Diplogonoporus brauni
Diplogonoporus fukuokaensis
Diplostomum spathaceum
Dipylidium caninum
Dirofilaria immitis
Dirofilaria repens
Dirofilaria striata
Dirofilaria subdermata
Dirofilaria tenuis
Dirofilaria ursi
Dracunculus insignis
Dracunculus medinensis
Drepanidotaenia lanceolata
Echinochasmus japonicus
Echinochasmus jiufoensis
Echinochasmus perfoliatus
Echinococcus granulosus
Synonyms and Notes
Spirometra
erinaceieuropaei,
Spirometra erinacei,
Prometra mansoni
Spirometra houghtoni
Spirometra mansonoides
Note: limited information
available
Diphyllobothrium
yonagoensis
Spirometra theileri
Diplogonoporus grandis
Dirofilaria ursi
Dirofilaria subdermata
Dracunculus medinensis
Screening Criteria Used for Exclusion
1|2|3
4
X
X
X
X
X
X
X
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 47
Ashford and Crewe, 2003, p. 48
Ashford and Crewe, 2003, p. 87
Ashford and Crewe, 2003, p. 83
MCM-8, p. 634, 1209
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 55
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 56
Ashford and Crewe, 2003, p. 57
Ashford and Crewe, 2003, p. 57
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 57
Ashford and Crewe, 2003, 57
Ashford and Crewe, 2003, 57
Ashford and Crewe, 2003, p. 30
Ashford and Crewe, 2003, p. 60
Ashford and Crewe, 2003, p. 83
Ashford and Crewe, 2003, p. 83
Ashford and Crewe, 2003, p. 83
Ashford and Crewe, 2003, p. 84
Ashford and Crewe, 2003, p. 84
Ashford and Crewe, 2003, p. 84
Ashford and Crewe, 2003, p. 78
Ashford and Crewe. 2003, p. 78
Ashford and Crewe, 2003, p. 61
Ashford and Crewe, 2003, p. 35
Ashford and Crewe, 2003, p. 36
Ashford and Crewe, 2003, p. 36
Ashford and Crewe, 2003, p. 62
A23
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Echinococcus multilocularis
Echinococcus oligarthus
Echinococcus vogeli
Echinoparyphium recurvatum
Echinostoma cinetorchis
Echinostoma echinatum
Echinostoma hortense
Echinostoma ilocanum
Echinostoma jassyense
Echinostoma macrorchis
Echinostoma malayanum
Echinostoma revolutum
Enterobius gregorii
Enterobius vermicularis
Episthmium caninum
Eucoleus aerophilus
Eurytrema pancreaticum
Eustrongylides sp.
Fasciola gigantica
Fasciola hepatica
Fasciola indica
Fasciolopsis buski
Fibricola seoulensis
Gastrodiscoides hominis
Gigantobilharzia huttoni
Gigantobilharzia sturniae
Gnathostoma doloresi
Gnathostoma hispidum
Gnathostoma nipponicum
Gnathostoma spinigerum
Gongylonema pulchrum
Gymnophalloides sp.
Haemonchus contortus
Haplorchis pumilo
Haplorchis taichui
Haplorchis vanissima
Haplorchis yokogawai
Heterobilharzia americana
Heterophyes dispar
Heterophyes heterophyes
Heterophyes nocens
Heterophyopsis continua
Himasthala muehlensi
Hymenolepis diminuta
Synonyms and Notes
Echinostoma melis
Fasciola gigantica
Neodiplostomum
seoulense
Fischeroederius elongatus
Screening Criteria Used for Exclusion
1|2|3
4
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 62
Ashford and Crewe, 2003, p. 62
Ashford and Crewe, 2003, p. 62
Ashford and Crewe, 2003, p. 36
Ashford and Crewe, 2003, p. 36
Ashford and Crewe, 2003, p. 37
Ashford and Crewe, 2003, p. 37
Ashford and Crewe, 2003, p. 37
Ashford and Crewe, 2003, p. 38
Ashford and Crewe, 2003, p. 37
Ashford and Crewe, 2003, p. 38
Ashford and Crewe, 2003, p. 38
Ashford and Crewe, 2003, p. 75
Ashford and Crewe, 2003, p. 75
Ashford and Crewe, 2003, p. 38
Ashford and Crewe, 2003, p. 89
Ashford and Crewe, 2003, p. 48
Ashford and Crewe, 2003, p. 87
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 30
Ashford and Crewe, 2003, p. 40
Ashford and Crewe, 2003, p. 31
Ashford and Crewe, 2003, p. 32
Ashford and Crewe, 2003, p. 78
Ashford and Crewe. 2003, p. 79
Ashford and Crewe. 2003, p. 79
Ashford and Crewe, 2003, p. 79
Ashford and Crewe, 2003, p. 80
Ashford and Crewe, 2003, p. 40,
138
Ashford and Crewe, 2003, p. 71
Ashford and Crewe, 2003, p. 42
Ashford and Crewe, 2003, p. 42
Ashford and Crewe, 2003, p. 42
Ashford and Crewe, 2003, p. 42
Ashford and Crewe, 2003, p. 32
Ashford and Crewe, 2003, p. 43
Ashford and Crewe, 2003, p. 43
Ashford and Crewe, 2003, p. 43
Ashford and Crewe, 2003, p. 43
Ashford and Crewe, 2003, p. 38
Ashford and Crewe, 2003, p. 61
A24
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Hymenolepis nana
Hypoderaeum conoideum
Inermicapsifermadagascariensis
Isopamrchis hypselobagri
Lagochilascaris minor
Ligula intestinalis
Loa loa
Macracanthorhynchus
hirudinaceus
Macracanthorhynchus ingens
Mammomonogamus laryngeus
Mammomonogamus nasicola
Mansonella ozzardi
Mansonella perstans
Mansonella rodhaini
Mansonella semiclarum
Mansonella streptocerca
Marshallagia marshalli
Mathevotaenia symmetrica
Mecistocirrus digitatus
Meningonema peruzzii
Mesocestoides lineatus
Mesocestoides variabilis
Metagonimus minutus
Metagonimus yokogawai
Metastrongylus elongatus
Metorchis albidus
Metorchis conjunctus
Microfilaria bolivarensis
Micronema deletrix
Moniezia expansa
Moniliformis moniliformis
Multiceps brauni
Multiceps glomeratus
Multiceps longihamatus
Multiceps multiceps
Multiceps serialis
Nanophyetus salmincola
Necator americanus
Nematodirus abnormalis
Neodiplostomum sp.
Synonyms and Notes
Microfilaria semiclarum
Note: Original publication
ambiguous, probably not a
human pathogen.
Halicephalobus gingivalis
Taenia brauni
Note: Unreliably identified,
probably not a human
pathogen.
Fibricola seoulensis
Screening Criteria Used for Exclusion
1|2|3
4
X
X
X
X
X
X
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 61
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 59
Ashford and Crewe, 2003, p. 31
Ashford and Crewe, 2003, p. 77
Ashford and Crewe, 2003, p. 57
Ashford and Crewe, 2003, p. 84
Ashford and Crewe, 2003, p. 93
Ashford and Crewe, 2003, p. 93
Ashford and Crewe, 2003, p. 71
Ashford and Crewe, 2003, p. 71
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 86
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 71
Ashford and Crewe, 2003, p. 60
Ashford and Crewe, 2003, p. 113
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 61
Ashford and Crewe, 2003, p. 62
Ashford and Crewe, 2003, p. 44
Ashford and Crewe, 2003, p. 44
Ashford and Crewe, 2003, p. 74
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 85
Ashford and Crewe, 2003, p. 67
Ashford and Crewe, 2003, p. 60
Ashford and Crewe, 2003, p. 94
Ashford and Crewe, 2003, p. 62
Ashford and Crewe, 2003, p. 63
Ashford and Crewe, 2003, p. 63
Ashford and Crewe, 2003, p. 63
Ashford and Crewe, 2003, p. 63
Ashford and Crewe, 2003, p. 52
Ashford and Crewe, 2003, p. 70
Ashford and Crewe, 2003, p. 113
Ashford and Crewe, 2003, p. 30
A25
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Oesophagostomum aculeatum
Oesophagostomum bifurcum
Oesophagostomum
stephanostomum
Onchocerca volvulus
Opisthorchis (Chlonorchis)
sinensis
Opisthorchis felineus
Opisthorchis guayaquilensis
Opisthorchis noverca
Opisthorchis viverrini
Orientobilharzia turkestanica
Ornithobilharzia sp.
Ostertagia ostertagi
Paragonimus africanus
Paragonimus bankokensis
Paragonimus caliensis
Paragonimus heterotremus
Paragonimus hueitungensis
Paragonimus kellicotti
Paragonimus mexicanus
Paragonimus miyazakii
Paragonimus ohirai
Paragonimus phillipinensis
Paragonimus sadoensis
Paragonimus siamensis
Paragonimus skrjabini
Paragonimus uterobilateralis
Paragonimus westermani
Parascaris equorum
Parastrongylus cantonensis
Parastrongylus costaricensis
Pearsonema plica
Pelodera strongyloides
Phaneropsolus bonnei
Philophthalmus lacrymosus
Phocanema decipiens
Physaloptera caucasica
Synonyms and Notes
Clonorchis sinensis
Note: Doubtful record,
probably not a human
pathogen.
Note: Human infection
unknown
Note: Human infection
unknown
Paragonimus skrjabini
Paragonimus westermanii
Paragonimus ohirai
Note: Capillaria plica
according to
http://www.biolib.cz/en/taxo
n/id87491 and
Screening Criteria Used for Exclusion
1|2|3
4
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 70
Ashford and Crewe, 2003, p. 70
Ashford and Crewe, 2003, p. 70
Ashford and Crewe, 2003, p. 86
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 46
Ashford and Crewe, 2003, p. 110
Ashford and Crewe, 2003, p. 47
Ashford and Crewe, 2003, p. 32
Kolarova, 2007
Ashford and Crewe, 2003, p. 71
Ashford and Crewe, 2003, p. 50
Ashford and Crewe, 2003, p. 110
Ashford and Crewe, 2003, p. 1 1 1
Ashford and Crewe, 2003, p. 50
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 50
Ashford and Crewe, 2003, p. 50
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 51
Palmer etal., 1998, p. 736
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 51
Ashford and Crewe, 2003, p. 77
Ashford and Crewe, 2003, p. 74
Ashford and Crewe, 2003, p. 74
MCM-8, p. 1134
Ashford and Crewe, 2003, p. 67
Ashford and Crewe, 2003, p. 48
Ashford and Crewe, 2003, p. 39
Ashford and Crewe, 2003, p. 76
Ashford and Crewe, 2003, p. 79
A26
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Physaloptera transfuga
Plagiorchis harinasutai
Plagiorchis javensis
Plagiorchis muris
Plagiorchis philippinensis
Poikilorchis congolensis
Procerovum calderoni
Prohemistomum vivax
Prosthodendrium molenkampi
Pseudamphistomum aethiopicum
Pseudamphistomum truncatum
Psilorchis hominis
Pygidiopsis summa
Pyramicocephalus
anthrocephalus
Raillietina celebensis
Raillietina demerariensis
Rhabditis elongate
Rhabditis inermis
Rhabditis niellyi
Rhabditis pellio
Rictularia sp.
Schistocephalus solidus
Schistosoma bovis
Schistosoma haematobium
Schistosoma intercalatum
Schistosoma japonicum
Schistosoma malayensis
Schistosoma mansoni
Schistosoma mattheei
Schistosoma mekongi
Schistosoma rodhaini
Schistosoma spindale
Schistosomatium douthitti
Setaria equina
Spirocerca lupi
Stellantchasmus falcatus
Stictodora fuscata
Strongyloides fuelleborni
Synonyms and Notes
Note: Validity questionable,
probably not a human
pathogen.
Note: Old and doubtful
record, probably not a
human pathogen.
Note: Probably
pseudoparasite, not a
human pathogen.
Screening Criteria Used for Exclusion
1|2|3
4
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 80
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 49
Ashford and Crewe, 2003, p. 44
Ashford and Crewe, 2003, p. 29
Ashford and Crewe, 2003, p. 48
Ashford and Crewe, 2003, p. 47
Ashford and Crewe, 2003, p. 47
Ashford and Crewe, 2003, p. 110
Ashford and Crewe, 2003, p. 45
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 60
Ashford and Crewe, 2003, p. 60
Ashford and Crewe, 2003, p. 67
Ashford and Crewe, 2003, p. 67
Ashford and Crewe, 2003, p. 1 1 1
Ashford and Crewe, 2003, p. 1 1 1
Ashford and Crewe, 2003, p. 80
Ashford and Crewe, 2003, p. 58
Ashford and Crewe, 2003, p. 32
Ashford and Crewe, 2003, p. 32
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 33
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 86
Ashford and Crewe, 2003, p. 81
Ashford and Crewe, 2003, p. 45
Ashford and Crewe, 2003, p. 45
Ashford and Crewe, 2003, p. 67
A27
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Strongyloides papillosus
Strongyloides ransomi
Strongyloides stercoralis
Strongyloides westeri
Syphacea obvelata
Taenia crassiceps
Taenia saginata
Taenia solium
Taenia taeniaeformis
Teladorsagia circumcincta
Ternidens deminutus
Thelazia californiensis
Thelazia callipaeda
Thelazia rhodesii
Toxascaris leonina
Toxocara canis
Toxocara cati
Trichinella britovi
Trichinella nativa
Trichinella nelson!
Trichinella pseudospiralis
Trichinella spiralis
Trichinella T5
Trichobilharzia brevis
Trichobilharzia ocellata
Trichobilharzia stagnicolae
Trichostrongylus affinis
Trichostrongylus axei
Trichostrongylus brevis
Trichostrongylus calcaratus
Trichostrongylus capricola
Trichostrongylus colubriformis
Trichostrongylus instabilis
Trichostrongylus lerouxi
Trichostrongylus orientalis
Trichostrongylus probolurus
Trichostrongylus skrjabini
Trichostrongylus vitrinus
Trichuris suis
Trichuris trichiura
Trichuris vulpis
Uncinaria stenocephala
Watsonius watsoni
Wuchereria bancrofti
Synonyms and Notes
Note: Unknown as an
human parasite.
Trichinella murrelli
Note: Experimental
infection only
Screening Criteria Used for Exclusion
1|2|3
4
X
X
5 | 6
7
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
8 | 9
10
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
11 | 12
PCCL
Reference
Ashford and Crewe, 2003, p. 68
Ashford and Crewe, 2003, p. 68
Ashford and Crewe, 2003, p. 68
Ashford and Crewe, 2003, p. 68
Ashford and Crewe, 2003, p. 75
Ashford and Crewe, 2003, p. 63
Ashford and Crewe, 2003, p. 64
Ashford and Crewe, 2003, p. 64
Ashford and Crewe, 2003, p. 64
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 70
Ashford and Crewe, 2003, p. 80
Ashford and Crewe, 2003, p. 80
MCM-8, p. 363
Ashford and Crewe, 2003, p. 113
Ashford and Crewe, 2003, p. 77
Ashford and Crewe, 2003, p. 78
Ashford and Crewe, 2003, p. 87
Ashford and Crewe, 2003, p. 88
Ashford and Crewe, 2003, p. 88
Ashford and Crewe, 2003, p. 88
Ashford and Crewe, 2003, p. 88
Ashford and Crewe, 2003, p. 87
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 34
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 72
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 73
Ashford and Crewe, 2003, p. 74
Ashford and Crewe, 2003, p. 89
Ashford and Crewe, 2003, p. 89
Ashford and Crewe, 2003, p. 90
Ashford and Crewe, 2003, p. 112
Ashford and Crewe, 2003, p. 40
Ashford and Crewe, 2003, p. 86
A28
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Helminths
Wuchereria lewisi
287 Helminths
Synonyms and Notes
Wuchereria bancrofti
Screening Criteria Used for Exclusion
1 I 2
3
0 | 0
0
4
X
25
5 | 6
0 | 0
7
106
8 | 9
0 | 0
10
156
11
12
0
0
PCCL
PCCL = 0
Reference
Ashford and Crewe, 2003, p. 86
A29
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Absidia corymbifera
Acremonium alabamense
Acremonium curvulum
Acremonium falciforme
Acremonium kiliense
Acremonium potronii
Acremonium recifei
Acremonium roseogriseum
Acremonium strictum
Acrophialophora fusispora
Actinomadura madurae
Actinomadura pelletieri
Alternaria alternata
Alternaria chlamydospora
Alternaria dianthicola
Alternaria infectoria
Alternaria longipes
Alternaria stemphyloides
Alternaria tenuissima
Aphanoascus fulvescens
Apophysomyces elegans
Arthrinium phaeospermum
Arthrographis kelrae *
Aspergillus candidus
Aspergillus clavatus
Aspergillus fisherianus
Aspergillus flavipes
Aspergillus flavus group
Aspergillus fumigatus group
Aspergillus glaucus
Aspergillus nidulans group
Aspergillus niger
Aspergillus oryzae
Aspergillus terreus group
Aspergillus versicolor
Aspergillus wentii
Aureobasidium pullulans
Basidiobolus ranarum
Beauveria bassiana
Bipolaris australiensis
Bipolaris hawaiiensis
Bipolaris spicifera
Synonyms and Notes
Actinomadura spp. are
bacteria, not fungi
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Aspergillus
fumigatus
Reference
MCM-9, p. 1839-1840, 1848
MCM-9, p. 1828
MCM-9, p. 1828
MCM-9, p. 1828
MCM-9, p. 1828
MCM-9, p. 1828
MCM-9, p. 1828
Howard, p. 384
MCM-9, p. 1828
MCM-9, p. 1802, 1808
MCM-9, p. 516, 520
MCM-9, p. 516, 520
MCM-9, p. 1898
MCM-9, p. 1898
MCM-9, p. 1898
MCM-9, p. 1898
MCM-9, p. 1898
httD://www.doctorfunaus.ora/the
funai/Alternaria.htm
MCM-9, p. 1898
MCM-9, p. 1802, 1808
MCM-9, p. 1839-1840
httD://www.doctorfunaus.ora/the
funai/Arthrinium.htm
Warris et al., 2001
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1807
MCM-9, p. 1898
MCM-9, p. 1839-1840
MCM-9, p. 1802, 1828
MCM-9, p. 1898
MCM-9, p. 1898
MCM-9, p. 1898
A30
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Blastomyces dermatitidis
Blastoschizomyces capitatus
Botryomyces caespitosus
Botryosphaeria subglobosa
Candida albicans
Candida catenulata
Candida famata
Candida glabrata
Candida guilliermondii
Candida haemulonis
Candida intermedia
Candida kefyr
Candida krusei
Candida lambica
Candida lipolytica
Candida lusitaniae
Candida norvegensis
Candida parapsilosis
Candida rugosa
Candida tropicalis
Candida viswanathii
Candida zeylanoides
Cephaliophora irregularis
Cerinosterus cyanescens
Chaetomium atrobtunneum
Chaetomium funicola
Chaetomium globosum
Chaetomium perpulchrum
Chaetomium strumarium
Chaetophoma dermo-unguis
Chlamydoabsidia padenii
Synonyms and Notes
Neodeightonia
subglobosa, Sphaeropsis
subglobosa
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
X
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
MCM-9, p. 1861
MCM-9, p. 1762, 1770-1771
Howard p. 575
httD://newDortal.abif.ora/SDecies
71 437351 3 and
http://www.cabri.ora/CABRI/srs-
bin/waetz?-newld+-e+-
paae+aResult+[CABI FIL-
id:'IMI%20287616'l
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
httD://www.doctorfunaus.ora/the
funai/Candida spp.htm
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
MCM-9, p. 1764, 1770-1771
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Cephaliopho
ra.htm
http://www.doctorfunaus.ora/the
funai/Sporothrix.htm
MCM-9, p. 1802, 1823-1824
http://www.doctorfunaus.ora/the
funai/Chaetomium.htm
MCM-9, p. 1802, 1823-1824
httD://www.doctorfunaus.ora/the
funai/Chaetomium.htm
MCM-9, p. 1802, 1823-1824
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Chaetophom
a. htm
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Chlamvdoab
sidia.htm
A31
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Chlorella protothecoides
Chrysosporium zonatum*
Chrysonilia sitophila
Cladophialophora arxii
Cladophialophora bantiana
Cladophialophora boppii
Cladophialophora carrionii
Cladophialophora devriesii
Cladorrhinum bulbillosum
Cladosporium cladosporioides
Cladosporium elatum
Cladosporium oxysporum
Cladosporium sphaerosphermum
Coccidioides immitis
Cokeromyces recurvartus
Colletotrichum coccodes
Colletotrichum dematium
Colletotrichum gloeosporioides
Conidiobolus coronatus
Conidiobolus incongruus
Conidiobolus lamprauges
Coniothyrium fuckelii
Coprinus cinereus
Cryptococcus neoformans
Cunninghamella bertholletiae
Curvularia brachyspora
Curvularia clavata
Curvularia geniculata
Curvularia lunata
Curvularia pallescens
Curvularia senegalensis
Curvularia verucculosa
Cylindrocarpon cyanescens
Cylindrocarpon lichenicola
Synonyms and Notes
Note: Chlorella spp. are
algae, not fungi.
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
httD://DCD.oxfordiournals.ora/cai
/content/abstract/9/1 787
Arvanitidou et al., 1999
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/Chrvsonilia.
htm
MCM-9, p. 1898, 1900-1902
MCM-9, p. 1898, 1900-1902
MCM-9, p. 1898, 1900-1902
MCM-9, p. 1898, 1900-1902
MCM-9, p. 1898, 1900-1902
httD://uwadmnweb. uwvo.edu/bo
tanv/Soil%20Microfunaal%20C
ollection/RMF%20collection%2
0(Rockv%20Mountain%20Funa
ibartll.htm
MCM-9, p. 1898, 1904
httD://www.doctorfunaus.ora/the
funai/CladosDorium.htm
httD://www.doctorfunaus.ora/the
funai/CladosDorium.htm
MCM-9, p. 1898, 1904
MCM-9, p. 1861
MCM-9, p. 1839-1840
Howard p. 662-664
Howard p. 662-664
Howard p. 662-664
MCM-9, p. 1839-1840
MCM-9, p. 1839-1840
Howard p. 133-137
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/Coniothvriu
m.htm
MCM-9, p. 1802, 1826
MCM-9, p. 1765-1767, 1770-
1771
MCM-9, p. 1839-1840, 1849
Howard p. 584-586
Howard p. 584-586
MCM-9, p. 1918
MCM-9, p. 1918
Howard p. 584-586
Howard p. 584-586
Howard p. 584-586
MCM-9, p. 1802, 1808, 1818
MCM-9, p. 1802, 1808, 1818
A32
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Cylindrocarpon vaginae
Dichotomophthora portulacae
Dichotomophthompsis nymphaerum
Dissitimurus exedrus
Doratomyces stemonitis
Drechslera biseptata
Emmonsia crescens
Emmonsia pan/a
Engyodontium album
Epidermophyton floccosum
Exophiala dermatitidis
Exophiala jeanselmei
Exophiala moniliae
Exophiala pisciphila
Exophiala psychmphila
Exophiala salmonis
Exophiala spinifera
Exserohilum longirostratum
Exserohilum macginnisii
Fusarium aquaeductuum
Fusarium chlamydosporum
Fusarium dimerum
Fusarium incarnatum
Fusarium moniliforme
Fusarium napiforme
Fusarium nivale
Fusarium oxysporum
Fusarium pallidoroseum
Fusarium proliferatum
Fusarium sacchari
Fusarium solani
Fusarium subglutinans
Fusarium ventricosum
Fusarium verticillioides
Geotrichum candidum*
Hansenula anomala
Synonyms and Notes
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Exophiala
jeanselmei
Fusarium
solani
Reference
Howard p. 394
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/DichotomoD
hthora.htm
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/DichotomoD
hthoroDsis.htm
Howard p. 588
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Doratomvce
s.htm
Howard p. 588-589
MCM-9, p. 1860
MCM-9, p. 1860
MCM-9, p. 1802, 1828
MCM-9, p. 1881
MCM-9, p. 1898
Howard p. 590-596
Howard p. 590-596
httD://www.doctorfunaus.ora/the
funai/exophiala.htm
Howard p. 590-596
MCM-9, p. 1898, 1902
MCM-9, p. 1898, 1902
Howard p. 596-597
Howard p. 402
MCM-9, p. 1818
MCM-9, p. 1818
Howard p. 407-409
MCM-9, p. 1818
MCM-9, p. 1818
Howard p. 431
MCM-9, p. 1818
Howard p. 320, 418-421
MCM-9, p. 1818
MCM-9, p. 1818
MCM-9, p. 1818
httD://www.doctorfunaus.ora/the
funai/fusarium.htm
MCM-9, p. 1818
Rosenzweig et al., 1986
MCM-9, p. 1768, 1770-1771
A33
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Histoplasma capsulatum
Hortaea werneckii
Lasiodiplodia theobromae
Lecythophora hoffmannii
Lecythophora mutabilis
Leptosphaeria senegalensis
Leptosphaeria tompkinsii
Loboa loboi
Madurella grisea
Madurella mycetomatis
Malassezia furfur
Malassezia globosa
Malassezia obtusa
Malassezia pachydermatis
Malassezia restricta
Malassezia sloofiae
Malassezia sympodialis
Microascus cinereus
Microascus cirrosus
Microsporum audouinii
Microsporum canis
Microsporum equinum
Microsporum ferrugineum
Microsporum fulvum
Microsporum gallinae
Microsporum gypseum
Microsporum nanum
Microsporum persicolor
Microsporum praecox
Microsporum racemosum
Microsporum vanbreuseghemii
Moniliella suavelolens
Synonyms and Notes
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
X
X
X
X
X
X
X
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
MCM-9, p. 1860
MCM-9, p. 1898, 1904
MCM-9, p. 1898, 1904
MCM-9, p. 1802, 1828
MCM-9, p. 1802, 1828
MCM-9, p. 1922
MCM-9, p. 1922
httD://www.doctorfunaus.ora/the
funai/Lacazia.htm
MCM-9, p. 1922
MCM-9, p. 1922
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1767-1768, 1770-
1771
MCM-9, p. 1802, 1823-1824,
1904
MCM-9, p. 1802, 1823-1824,
1904
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881; Howard p.
170
MCM-9, p. 1881
MCM-9, p. 1881; Howard p.
156, 181
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/Moniliella.ht
m
A34
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Mucor circinelloides
Mucor hiemalis
Mucor indicus
Mucor racemosus
Mucor ramosissimus
Myceliophthora thermophila
Mycocentrospora acerina
Mycoleptodiscus indicus
Myriodontium keratinophilum
Nannizzia cajetani
Nattrassia mangiferae
Neocosmospora vasinfecta
Neotestudina rosatii
Nigrospora sphaerica
Ochroconis gallopava
Oidiodendron cerealis
Onychocola canadensis
Ovadendron ochraceum
Ovadendron sulphureo-ochraceum
Paecilomyces farinosus
Paecilomyces fumerosoreus
Paecilomyces javanicus
Paecilomyces lilacinus
Paecilomyces marquandii
Paecilomyces variotii
Paecilomyces viridis
Paracoccidioides brasiliensis
Penicillium chrysogenum
Penicillium citrinum
Penicillium commune
Penicillium decumbens
Penicillium dupontii
Penicillium expansum
Penicillium marneffei
Penicillium purpurogenum
Phaeoanellomyces elegans
Phaeoanellomyces werneckii
Synonyms and Notes
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
MCM-9, p. 1839-1840, 1851
MCM-9, p. 1839-1840, 1851
Howard p. 70, 98-99, 101
MCM-9, p. 1839-1840, 1851
MCM-9, p. 1839-1840, 1851
MCM-9, p. 1802, 1828
Howard p. 602-603
Howard p. 602-603
MCM-9, p. 1802, 1828
Howard p. 155
MCM-9, p. 1898, 1904
Howard p. 434-436
MCM-9, p. 1918-1921
httD://www.doctorfunaus.ora/the
funai/Niarospora.htm
MCM-9, p. 1898, 1902
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Oidiodendro
n.htm
MCM-9, p. 1802, 1828
http://www.cataloaueoflife.ora/s
how species details. php?recor
d id-3330913
Howard p. 230-232
httD://www.doctorfunaus.ora/the
funai/Paecilomvces.htm
Howard p. 361-362
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
Howard p. 357-359
MCM-9, p. 1861
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1829
Howard p. 340-346
MCM-9, p. 1802, 1829
MCM-9, p. 1802, 1822
MCM-9, p. 1802, 1829
Howard p. 605-606
MCM-9, p. 1898, 1904
A35
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Phaeosclera dematioides
Phaeotrichoconis crotalariae
Phialemonium curvatum
Phialemonium obovatum
Phialophora bubakii
Phialophora pedrosoi
Phialophora repens
Phialophora richardsiae
Phialophora verrucosa
Phoma cava
Phoma cruris-hominis
Phoma eupyrena
Phoma glomerata
Phoma herbarum
Phoma hibernica
Phoma minutella
Phoma oculo-hominis
Phyllosticta citricarpa
Piedraia hortae
Pleurophoma pleurospora
Pneumocystis carinii
Prototheca wickerhamii
Prototheca zopfii
Pseudoallescheria boydii
Pseudomicrodochium suttonii
Pyrenochaeta mackinnonii
Pyrenochaeta romeroi
Pyrenochaeta unguis-hominis
Pythium insidiosum
Rhinocladiella aquaspersa
Rhinocladiella compacta
Rhinocladiella obovoidea
Rhinocladiella schulzeri
Rhinosporidium seeberi
Synonyms and Notes
Petrielidium boydii
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
6
X
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/Phaeosclera
.htm
Howard p. 606-607
MCM-9, p. 1898, 1900
MCM-9, p. 1898, 1900
Howard p. 607-612
httD://www.doctorfunaus.ora/the
funai/Fonsecaea.htm
MCM-9, p. 1898, 1902-1903
MCM-9, p. 1898, 1902-1903
MCM-9, p. 1898, 1902-1903
http://www.doctorfunaus.ora/the
funai/phoma.htm
Howard p. 666-668
Howard p. 666-668
Howard p. 666-668
httD://www.doctorfunaus.ora/the
funai/phoma.htm
Howard p. 666-668
Howard p. 666-668
Howard p. 666-668
http://www.doctorfunaus.ora/the
funai/phoma.htm
MCM-9, p. 1891
Howard p. 666-668
MCM-9, p. 1789-1791
MCM-9, p. 1770-1771, 1779
MCM-9, p. 1770-1771, 1779
MCM-9, p. 1922
MCM-9, p. 1898, 1902
MCM-9, p. 1918, 1921-1922
MCM-9, p. 1918, 1921-1922
Howard p. 666-668
MCM-9, p. 1936-1939
MCM-9, p. 1898, 1904
http://www.doctorfunaus.ora/the
funai/Fonsecaea.htm
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Ramichloridi
urn. htm
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Ramichloridi
urn. htm
MCM-9, p. 1936-1937, 1942-
1943
A36
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Rhizomucor miehei
Rhizomucor pusillus
Rhizopus azygosporus
Rhizopus microsporus
Rhizopus oryzae
Rhizopus stolonifer
Rhodotorula glutinis
Rhodotorula minuta
Rhodotorula mucilaginosa
Rhodotorula rubra
Saccharomyces cerevisiae
Saksenaea vasiformis
Sarcinomyces phaeomuriformis
Scedosporium prolificans
Schizophyllum commune
Scolecobasidium humicola
Scolecobasidium tshawytschae
Scopulariopsis acremonium
Scopulariopsis asperula
Scopulariopsis brevicaulis
Scopulariopsis brumptii
Scopulariopsis Candida
Scopulariopsis flava
Scopulariopsis fusca
Scytalidium hyalinum
Scytalidium infestans
Setosphaeria rostrata
Sporothrix schenckii
Sporotrichum pruinosum*
Stachybotrys chartarum*
Stemphylium macrosporoideum *
Stenella araguata
Streptomyces somaliensis
Taeniolella exilis
Taeniolella stilbaspora
Tetraploa aristata
Thermomyces lanuginosus
Synonyms and Notes
Nattrassia mangiferae
Exserohilum rostratum
Note: Streptomyces spp.
are bacteria, not fungi
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
5
X
X
X
X
6
7 I 8
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
10
11 | 12
PCCL
Reference
MCM-9, p. 1839-1840
MCM-9, p. 1839-1840
MCM-9, p. 1839-1840,
MCM-9, p. 1839-1840,
MCM-9, p. 1839-1840, 1847
MCM-9, p. 1839-1840,
MCM-9, p. 1768, 1770-1771
MCM-9, p. 1768, 1770-1771
MCM-9, p. 1768, 1770-1771
MCM-9, p. 1768, 1770-1771
MCM-9, p. 1768, 1770-1771
MCM-9, p. 1839-40, 1850
MCM-9, p. 1898-1902
MCM-9, p. 1821
MCM-9, p. 1802, 1826
Howard p. 617
Howard p. 617
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1823
MCM-9, p. 1904
htto://www. scielo.br/scielo. oho?
script=sci arttext&pid=S0036-
46651 999000500009&lna=Dt&n
rm=iso&tlna=Dt
MCM-9, p. 1900; Palmer, p.
565, 597
MCM-9, p. 1898, 1906
Doggett, 2000
Doggett, 2000
West 1986
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/Stenella.htm
MCM-9, p. 519-520
Howard p. 621
Howard p. 621
Howard p. 621-623
Howard p. 623
A37
-------
EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Fungi
Torulopsis magnoliae
Trichoderma pseudokoningii
Trichoderma viride
Trichomaris invadens
Trichophyton ajelloi
Trichophyton concentricum
Trichophyton equinum
Trichophyton gallinae
Trichophyton gourvilii
Trichophyton megninii
Trichophyton mentagrophytes
Trichophyton rubrum
Trichophyton schoenleinii
Trichophyton simii
Trichophyton soudanense
Trichophyton tonsurans
Trichophyton verrucosum
Trichophyton violaceum
Trichosporon asahii
Trichosporon beigelii
Trichosporon cutaneum
Trichosporon inkin
Trichosporon mucoides
Trichosporon ovoides
Tritirachium oryzae
Tubercularia vulgaris
Ulocladium chartarum
Veronaea botryosa
Verticillium nigrescens
Volutella cinerescens
313 Fungi
Synonyms and Notes
Screening Criteria Used for Exclusion
1 I 2 | 3 | 4
0 | 0 | 0 | 0
5
12
6
1
7 I 8
0 | 0
9
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
297
10
0
11 | 12
0 | 0
PCCL
PCCL = 3
Reference
httD://www.doctorfunaus.ora/im
aaeban/svnonvms/ToruloDsis.ht
m
MCM-9, p. 1802, 1828-1829
MCM-9, p. 1802, 1828-1829
http://www.pac.dfo-
mpo.ac.ca/sci/shelldis/paaes/ch
itfdcb e.htm
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881; Howard p.
173
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1881
MCM-9, p. 1769-1771
MCM-9, p. 1769-1771
MCM-9, p. 1769-1771
MCM-9, p. 1769-1771
MCM-9, p. 1769-1771
MCM-9, p. 1769-1771
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Tritirachium.
htm
Howard p. 448-449
Howard p. 623-624
http://www.doctorfunaus.ora/im
aaeban/svnonvms/Veronaea.ht
m
Howard p. 449-450
Howard p. 451
*Fungi identified by an asterisk were added to the microbial CCL universe by EPA because they were found in biofilm of drinking water distribution sytems in the U.S.
MCM-9 refers to the Manual of Clinical Microbiology, 9th Edition \ \ |
A38
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EPA-OGWDW
CCL 3 Microbes: Screening to the PCCL
Attachment A: Screening to the PCCL
EPA815-R-08-006
February 2008 - DRAFT
Summary
Pathogen
Bacteria
Viruses
Protozoa1
Helminths
Fungi
Total
Total No.
540
219
66
287
313
1,425
Screening Criteria Used for Exclusion
1
125
0
0
0
0
125
2
14
0
0
0
0
14
3
10
26
1
0
0
37
4
37
104
29
25
0
195
5
117
0
3
0
12
132
6
7
19
0
0
1
27
7
0
1
4
106
0
111
8
29
18
7
0
0
54
9
154
0
7
0
297
458
10
2
36
0
156
0
194
11
28
8
6
0
0
42
12
5
0
0
0
0
5
PCCL No.
12
7
7
0
3
29
1 Cryptosporidium and Giardia are considered to be regulated by LT2. They were not subjected to the screening process, though they were used as examples of contaminants that need to be regulated to validate screening
criteria and scoring protocols. These organisms will not be listed on CCL3.
A39
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