United States Prevention, Pesticides EPA Environmental Protection and Toxic Substances September 2007 Agency (7508P) Reregistration Eligibility Decision for Aldicarb ------- Reregistration Eligibility Decision (RED) Document for Aldicarb List A Case Number 0140 Approved by: Date: Steven Bradbury, Ph.D. Director Special Review and Reregistration Division Page 2 of 191 ------- Table of Contents Aldicarb Reregi strati on Eligibility Decision Team 5 Glossary of Terms and Abbreviations 6 Abstract 8 I. Introduction 9 II. Chemical Overview 11 A. Chemical Identity 11 B. Regulatory History 12 C. Use and Usage Profile 12 D. Tolerances 13 III. Aldicarb Human Health and Environmental Fate and Effects Risk Assessments 14 A. Human Health 14 B. Environmental Fate and Effects 14 IV. Risk Management, Reregi strati on Decision, and Tolerance Reassessment Decisions 18 A. Determination of Reregistration Eligibility 18 B. Public Comments and Responses 18 C. Regulatory Position 19 1. Food Quality Protection Act Findings 19 a. "Risk Cup" Determination 19 b. Determination of Safety to U.S. Population (Including Infants and Children) 19 c. Endocrine Disrupter Effects 19 d. Cumulative Risks 20 2. Tolerance Summary 20 D. Regulatory Rationale 22 1. Human Health Risk Management and Mitigation 22 a. Dietary Risk Mitigation (Food and Drinking Water) 22 b. Aggregate Risk Mitigation 23 c. Occupational Risk Mitigation 23 2. Ecological Risk Management and Mitigation 23 a. Terrestrial and Aquatic Organisms 23 3. Mitigation Summary and Crop-Specific Analyses 24 Citrus 25 Cotton 27 Dry Bean 30 Peanut 31 Potato 34 Soybean 36 Sugar Beet 37 Sweet Potato 40 4. Other Labeling Requirements 41 5. Threatened and Endangered Species Considerations 41 V. What Registrants Need to Do 43 A. Manufacturing-Use Products 43 1. Additional Generic Data Requirements 43 2. Labeling for Manufacturing-Use Products 43 Page 3 of 191 ------- B. End-Use Products 44 1. Additional Product-Specific Data Requirements 44 2. Labeling for End-Use Products 44 Appendix A. Aldicarb Uses and Use-Patterns Eligible for Reregi strati on 58 Appendix B. Table of Generic Data Requirements and Studies Used to Make the Reregi strati on Decision 68 Appendix C. Technical Support Documents 75 Appendix D. Citations Considered to be Part of the Database Supporting the Reregi strati on Decision (Bibliography) 77 Appendix E. Generic Data Call-In (GDCI) 183 Appendix F. Product-Specific Data Call-In (PDCI) 184 Appendix G. EPA's Batching of Aldicarb Products for Meeting Data Requirements for Reregi strati on 185 Appendix H. List of Available Related Documents and Electronically Available Forms 187 Page 4 of 191 ------- Aldicarb Reregistration Eligibility Decision Team EPA Office of Pesticide Programs Special Review and Reregistration Division Sherrie Kinard Anne Overstreet Robert McNally Health Effects Division Jeff Dawson Felicia Fort Michael Metzger Linda Taylor Environmental Fate and Effects Division Jonathan Angier Tom Bailey Jeanette Martinez Dana Spatz Biological and Economic Analysis Division Derek Berwald Angel Chiri Colwell Cook Arnet Jones Monisha Kaul Timothy Kiely Istanbul Yusuf Nicole Zinn Registration Division Joanne Edwards John Hebert PageS of 191 ------- Glossary of Terms and Abbreviations AGDCI ai aPAD BCF CFR cPAD CSF CSFII DCI DEEM DFR DNT EC EDWC EEC EPA EUP FDA FIFRA FFDCA FQPA GLN IR LD5 '50 LOC LOAEL MATC mg/kg/day mg/L MOE MRID MUP NOAEL OPP Agricultural Data Call-In Active Ingredient Acute Population Adjusted Dose Bioconcentration Factor Code of Federal Regulations Chronic Population Adjusted Dose Confidential Statement of Formulation USDA Continuing Surveys for Food Intake by Individuals Data Call-In Dietary Exposure Evaluation Model Dislodgeable Foliar Residue Developmental Neurotoxicity Emulsifiable Concentrate Formulation Estimated Drinking Water Concentration Estimated Environmental Concentration Environmental Protection Agency End-Use Product Food and Drug Administration Federal Insecticide, Fungicide, and Rodenticide Act Federal Food, Drug, and Cosmetic Act Food Quality Protection Act Guideline Number Index Reservoir Median Lethal Concentration. A statistically derived concentration of a substance that can be expected to cause death in 50% of test animals. It is usually expressed as the weight of a substance per weight or volume of water, air, or feed, e.g., mg/1, mg/kg, or ppm. Median Lethal Dose. A statistically derived single dose that can be expected to cause death in 50% of the test animals when administered by the route indicated (oral, dermal, inhalation). It is expressed as a weight of substance per unit weight of animal, e.g., mg/kg. Level of Concern Lowest Observed Adverse Effect Level Maximum Acceptable Toxicant Concentration Micrograms Per Gram Micrograms Per Liter Milligram Per Kilogram Per Day Milligram Per Liter Margin of Exposure Master Record Identification Number. EPA's system for recording and tracking studies submitted. Manufacturing-Use Product No Observed Adverse Effect Level EPA Office of Pesticide Programs Page 6 of 191 ------- OPPTS PAD PCA PDF PHED PHI ppb PPE ppm PRZM/EXAMS Q* RAC RED REI RfD RQ SCI-GROW2 SAP SF SLC TGAI USDA USGS UF UV WPS EPA Office of Prevention, Pesticides, and Toxic Substances Population Adjusted Dose Percent Crop Area USDA Pesticide Data Program Pesticide Handler's Exposure Data Pre-harvest Interval Parts Per Billion Personal Protective Equipment Parts Per Million Pesticide Root Zone Mode/Exposure Analysis Modeling System, Tier II Surface Water Computer Model The Carcinogenic Potential of a Compound, Quantified by the EPA's Cancer Risk Model Raw Agriculture Commodity Reregi strati on Eligibility Decision Restricted-Entry Interval Reference Dose Risk Quotient Tier I Ground Water Computer Model Science Advisory Panel Safety Factor Single Layer Clothing Technical Grade Active Ingredient United States Department of Agriculture United States Geological Survey Uncertainty Factor Ultraviolet Worker Protection Standard Page 7 of 191 ------- Abstract This document presents the Environmental Protection Agency's (EPA's or the Agency's) decision regarding the reregi strati on eligibility of the registered uses of the active ingredient aldicarb. The Agency has conducted human health and environmental fate and effects risk assessments for aldicarb and has assessed whether the aldicarb tolerances are safe from an individual-chemical standpoint (considering all issues other than cumulative exposures to other n-methyl carbamate pesticides). The Agency has determined that, with label amendments and changes as specified in this document, aldicarb can be used without resulting in unreasonable adverse effects on the environment, and that there is a reasonable certainty that no harm will result to the general U.S. population, infants, children, or other major identifiable population subgroups, from the use of aldicarb (considering all issues other than cumulative exposures to other n-methyl carbamate pesticides). The Agency has therefore determined that products containing the active ingredient aldicarb are eligible for reregi strati on provided that the risk mitigation measures outlined in this document are adopted and label amendments are made to reflect these measures. EPA has identified potential human health risks of concern associated with the current registered uses of aldicarb from drinking water exposure, and potential environmental risks of concern to birds, mammals and fish. To reduce these potential exposures and to address current risks of concern, the Agency, in agreement with the technical registrant of aldicarb, will implement label restrictions (increase drinking water well set-backs when certain criteria are triggered) for application to peanuts in the southeastern coastal plains for ground water contamination concerns. Additionally, application rate reductions, state limitations, application restrictions, label amendments, and termination of certain uses will also be implemented to reduce environmental concerns. The Agency is also requiring appropriate data to confirm the decisions presented in this Reregi strati on Eligibility Decision. Page 8 of 191 ------- I. Introduction The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) was amended in 1988 to accelerate the reregi strati on of products with active ingredients registered prior to November 1, 1984. The amended Act calls for the development and submission of data to support the reregi strati on of an active ingredient, as well as a review of all data submitted to the Environmental Protection Agency (hereafter referred to as EPA or the Agency). Reregi strati on involves a thorough review of the scientific database underlying a pesticide's registration. The purpose of the Agency's review is to reassess the potential hazards arising from the currently registered uses of a pesticide, to determine the need for additional data on health and environmental effects, and to determine whether or not the pesticide meets the "no unreasonable adverse effects" standard of FIFRA. On August 3, 1996, the Food Quality Protection Act (FQPA) was signed into law. This Act amended FIFRA and the Federal Food, Drug, and Cosmetic Act (FFDCA) to require reassessment of all existing tolerances for pesticides in food. EPA decided that, for those chemicals that have tolerances and are undergoing reregi strati on, tolerance reassessment would be accomplished through the reregi strati on process. Under FQPA, in reassessing these tolerances, the Agency must consider, among other things, aggregate risks from non- occupational sources of pesticide exposure, whether there is increased susceptibility among infants and children, and the cumulative effects of pesticides that have a common mechanism of toxicity. In determining whether aldicarb tolerances can be reassessed as safe, the Agency has concluded that the risks from aggregate exposure to aldicarb are acceptable, and that the tolerances can be reassessed as safe if they are acceptable when viewed in light of the cumulative assessment of n-methyl carbamate pesticides. The intentional dosing human toxicity study (the Inveresk study) used in the human health risk assessment for aldicarb has been reviewed by EPA's Human Studies Review Board, as required by EPA's Human Subjects Protections rule. The Agency presented the Inveresk study to the HSRB at a meeting on April 2-4, 2006. The HSRB discussed the study extensively and concluded that the cholinesterase data from the aldicarb human study were reliable for use in the aldicarb single chemical, aggregate risk assessment from both a science and ethical standpoint. The final report of the HSRB is available at http://www.epa.gov/osa/hsrb/files/april2006mtgfinalreport62606.pdf Risks summarized in this document are for aldicarb only. FQPA requires EPA to consider available information concerning the cumulative effects of a particular pesticide's residues and "other substances that have a common mechanism of toxicity" when considering whether to establish, modify, or revoke a tolerance. Potential cumulative effects of chemicals with a common mechanism of toxicity are considered because low-level exposure to multiple chemicals causing a common toxic effect by a common mechanism could lead to the same adverse health effect as would a higher level of exposure to any one of these individual chemicals. Aldicarb is a member of the N-methyl carbamate class of pesticides. The Agency has classified the N-methyl carbamate pesticides and their common degradates as having a common mechanism of toxicity. Page 9 of 191 ------- A cumulative risk assessment, which evaluates exposures based on a common mechanism of toxicity, was conducted to evaluate risk from food, drinking water, residential use, and other non-occupational exposures resulting from registered uses of N-methyl carbamate pesticides, including aldicarb. EPA has concluded that the cumulative risks associated with the N-methyl carbamate pesticides are below the Agency's level of concern. With this determination, the Agency has concluded the reassessment process for aldicarb tolerances mandated by section 408(q) of the FFDCA. For additional information, refer to the document, Revised N-methyl Carbamate Cumulative Risk Assessment, which is available in the EPA docket EPA-HQ-OPP-2007-0935 and on the website, http://www.epa.gov/pesticides/cumulative/. This document presents EPA's revised human health and environmental fate and effects risk assessments, its progress toward tolerance reassessment, and the reregi strati on eligibility decision for aldicarb. The document consists of six sections. Section I contains the regulatory framework for reregi strati on and tolerance reassessment. Section II provides a description of the chemical and a profile of the use and usage of the chemical. Section III references the revised human health and environmental fate and effects risk assessments attached as Appendices to this document. Section IV presents the Agency's risk management, reregi strati on eligibility, and tolerance reassessment decisions. Section V summarizes the data requirements necessary to confirm the reregi strati on eligibility decision as well as specific label changes and language necessary to implement the risk mitigation measures outlined in Section IV. Section VI, the Appendices, provides related information and supporting documents. The preliminary and revised risk assessments for aldicarb are available in the public docket EPA-HQ-OPP-2005-0163 located on-line in the Federal Docket Management System (FDMS) at http://www.regulations.gov. Page 10 of 191 ------- II. Chemical Overview A. Chemical Identity Chemical Structure: H,C 3 \ H O CH, CH, Empirical Formula: Common Name: C7H14N2O2S Aldicarb CAS Name: 2-methyl-2-(methylthio)propionaldehyde O- (methylcarbamoyl)oxime CAS Registry Number: 116-06-3 OPP Chemical Code: 098301 Case Number: 0140 Technical Registrant: Bayer CropSciences Degradates: Aldicarb sulfoxide: 2-Methyl-2-(methylsulfmyl)propionaldehyde O- (methyl carbamoyl) oxime, and Aldicarb sulfone: 2-Methyl-2- (methylsulfonyl)propionaldehyde O-(methyl carbamoyl) oxime The regulated residues are the combined residues of aldicarb and its two cholinesterase- inhibiting metabolites, aldicarb sulfoxide and aldicarb sulfone. Aldicarb sulfoxide is considered to have similar potency to the parent in terms of toxicity, while aldicarb sulfone is less potent. Aldicarb and the sulfoxide and sulfone metabolites are the residues of concern in both the tolerance expression and the reregi strati on decision. Aldicarb is registered for use as a systemic insecticide and nematicide on agricultural crops. Aldicarb is absorbed by the root system, and is subsequently translocated throughout the plant. Aldicarb is a restricted use pesticide and there are no aldicarb products intended for sale to homeowners or for use in residential settings. Aldicarb is currently sold in the United States by Bayer CropScience, the basic producer, under the trade name of Temik®. Page 11 of 191 ------- B. Regulatory History Aldicarb was first registered in 1970. Marketing of aldicarb was stopped in Long Island in 1980 due to high levels of aldicarb degradates found in ground water there. In 1981, aldicarb was classified as a restricted use pesticide and in 1984 was placed under Special Review. Aldicarb is currently under Special Review because of concerns regarding ground water contamination. Position Documents (PD's) 1 and 2/3 were published on 7/11/84 (49 FR 28320) and 6/29/88 (53 FR 24630), respectively. A Special Review Data Call-in-Notice (DCI) was issued 6/3/89 requiring the registrant to submit additional ground water data. In addition, because a National Food Survey identified discrepancies between anticipated residues in foods and actual residues from food survey samples, the Special Review required a variety of studies related to use on potatoes and citrus crops. In 1990, the sale of aldicarb on potatoes was voluntarily suspended due to detection of tolerance-exceeding aldicarb residues on individual potatoes. The registrant agreed to dietary risk reduction actions involving voluntary cancellation of use on bananas and registration amendments for uses on potatoes, sweet potatoes, oranges and grapefruit. The registrant subsequently submitted extensive field residue and commercial storage and processing data showing that more controlled application techniques would ensure residues below the established tolerance and would not pose any increased dietary risk. The use on potatoes was re-instated in the states of FL, ID, WA and OR, after new application methods demonstrated significantly lower residues in potatoes. Although dietary risk concerns relating to use on potatoes have been resolved, aldicarb remains in EPA's Special Review process because of concerns about risks of ground water contamination. In 1998, the Agency issued a proposal as part of Special Review to manage risks due to ground water concerns through national measures consisting of the prohibition of aldicarb use within 300 feet of a drinking water well, and geographically specific measures consisting of the requirement for State Management Plans. The Agency will begin the process to close out the Special Review of aldicarb in the near future. C. Use and Usage Profile The following is information on the currently registered uses of aldicarb. Sections IV and V include information on those currently registered uses which are eligible for reregi strati on and Appendix A provides a detailed table of those uses which are eligible for reregi strati on. Type of Pesticide: Aldicarb is a systemic insecticide, acaricide and nematicide used to control the following pests: a number of nematode species (suppression); leaf phylloxera; bud moth;; aphids; mites; white flies; thrips; fleahoppers, leafminers; leafhoppers; overwintering boll weevil; lygus; cotton leaf perforator; seedcorn maggot; Mexican bean beetle; flea beetles; Colorado potato beetle; greenbug; chinch bug; three cornered alfalfa hopper (suppression); and sugar beet root maggot. Page 12 of 191 ------- Formulations: Aldicarb is formulated and marketed solely as a granular pesticide under the trade name Temik®. The granulars (5, 10 and 15% a.i.) consist of aldicarb adhered to a corn cob grit or gypsum substrate, which are formulated to produce less dust than typical clay substrates used for granular pesticides. The gypsum granular is available in closed loading systems. Methods of Application: End-use products containing aldicarb are restricted use and can only be applied by a certified applicator. Typically, aldicarb is applied early in the growing season, either pre-plant, at-planting, or early post-emergent, using ground application equipment. Positive displacement application equipment and immediate soil incorporation are required. Aldicarb is also applied as a split-season use to peanuts. It is applied as a broadcast (at-pegging) to the canopy of the peanut plant for nematode control. Use Sites: Application Rates: Estimated Usage: No aldicarb products are intended for sale to homeowners or for use by professional applicators in residential environments. Aldicarb is currently registered for use on agricultural crops including citrus, cotton, dry beans, peanuts, pecans, potatoes, sorghum, soybeans, sugar beets, sugarcane, sweet potatoes, and seed alfalfa (CA). In addition, aldicarb may be applied to field grown ornamentals (CA), tobacco, and on coffee grown in Puerto Rico. The maximum application rates range from 1.05 pounds (Ibs) active ingredient (ai) per acre (A) for sorghum to 10.05 Ibs ai/A for pecans. Approximately 4.5 million pounds of aldicarb are used annually. Aldicarb is used mostly on cotton (approximately 64% of total aldicarb use). Other high use crops include peanuts, potatoes, sugar beets, and citrus. D. Tolerances Tolerances for aldicarb are expressed in terms of the combined residues of aldicarb and its cholinesterase-inhibiting metabolites aldicarb sulfoxide and aldicarb sulfone in plant, livestock, and processed food and feed commodities [40 CFR §180.269, §185.150 (a), and §186.150]. Section IV includes a summary of the tolerance reassessment decision for aldicarb and lists those tolerances the Agency will propose to revoke, decrease, increase, maintain, reassign, and establish. Page 13 of 191 ------- III. Aldicarb Human Health and Environmental Fate and Effects Risk Assessments Human health effects and environmental fate and effects risk assessments have been performed for aldicarb. These assessments demonstrate potential human health risks of concern for ground water contamination in the southeastern coastal plains resulting from the use on peanuts, and environmental risks of concern to both terrestrial and aquatic organisms resulting from all uses of aldicarb. A summary of potential risk concerns are presented below. For additional information and the risk assessments in their entirety, please refer to the revised human health and environmental fate and effects risk assessments for aldicarb, dated February 26, 2007, and November 30, 2005, respectively. These documents are also available in the public docket EPA-HQ-OPP-2005-0163 located on-line at http://www.regulations.gov. A. Human Health As discussed in Section 5.2 of the human health risk assessment (found at http://www.regulations.gov./), there are risk estimates that exceed EPA's level of concern from aggregate dietary exposure to residents living in the U.S. southeastern coastal plain who consume water from rural ground water wells. Four drinking water (from ground water sources) concentration scenarios were modeled for aldicarb: three ground water scenarios for use on peanuts/cotton in Georgia with an assumption of a 300 ft., 500 ft., and 1000 ft. setback, as well as an additional scenario in Florida for aldicarb use on citrus with a 1000 ft. setback. The estimated risks at the 99.9th percentile are below the Agency's level of concern for all four scenarios, and for all population subgroups except for infants under the Georgia 300ft. scenario (139% - 147% of the acute population adjusted dose (aPAD)). For all other scenarios, risk are not of concern to the Agency. B. Environmental Fate and Effects There are multiple lines of evidence, including studies in the open literature and registrant submitted data, clearly demonstrating that aldicarb is very highly toxic to both aquatic and terrestrial non-target organisms (e.g., a single granule of TEMIK® 15G can kill a small bird). However, the degree to which there is exposure to aldicarb or its degradates in the terrestrial and aquatic environments is much more uncertain. This is due in part to the physical properties (e.g., color, size, and solubility) of the aldicarb granule, the variety of application techniques, amounts applied, number of applications, application intervals, and timing of applications. Typically, the aldicarb granules are spread on the surface and incorporated into the soil by "shanking in", "working into the soil", "covering with soil", and/or "wetting in". Applications directly "in- furrow" are also performed for some crops (e.g., sweet potato), but may be followed by later applications that are less effectively soil-incorporated. The ecological risk assessment was conducted assuming that the aldicarb granules are incorporated into the soil with efficiencies ranging from 85 to 99 percent, leaving just 1 to 15 percent of the applied granules on the soil surface available to terrestrial organisms or to runoff to surface water (resulting in exposure to aquatic organisms). Certain application techniques, specifically, in-furrow applications and banded applications that utilize state-of-the-art methods (such as positive displacement and immediate soil incorporation), may theoretically result in incorporation efficiencies of 99 Page 14 of 191 ------- percent. Other types of applications may result in incorporation efficiencies closer to 85 percent. Because of this uncertainty, both scenarios were addressed in the ecological risk assessment. In addition to this, risk quotients were calculated for both maximum labeled rates and typical application rates, showing the range of expected outcomes. There are two aldicarb degradates of concern, aldicarb sulfoxide and aldicarb sulfone, that are also considered in the assessment. These degradates appear to form primarily in the shallow subsurface (although some may also form within plant tissue) and are potentially more mobile and persistent than the parent. As a conservative assumption, all three forms (parent aldicarb, sulfoxide, and sulfone) are considered as a single constituent for aquatic exposure estimates because of the longer degradate half-lives. Parent only is considered for terrestrial exposure because of its higher toxicity to animals, the likelihood that most exposure would be to whole granules, and because only small amounts of the degradates, relative to the parent, are expected to be present directly on the surface. Given the methods of application of the aldicarb granule (i.e., ground application and incorporation into the soil), its high water solubility, low vapor pressure, and low bioaccumulation potential, terrestrial exposure to aldicarb is primarily confined to the treated field. Off-site terrestrial exposure to aldicarb would be limited to cases where, 1) a granule is re- deposited to lower-lying areas affected by aldicarb runoff from nearby fields, or 2) a granule in the gut or on a prey item such as a small bird or mammal is consumed by a predator. The series of events that would need to transpire in order to result in off-site exposure are considered unlikely. Summarizing the risk to terrestrial organisms, the acute risk level of concern for birds and mammals is exceeded for all target crops at both maximum allowed label rates and typical use rates. The levels of concern are consistently exceeded by a factor of greater than 100X and are frequently exceeded by more than 1000X. These results consider both 85 and 99 percent incorporation efficiencies. The granules left exposed on the surface appear to be the main source of exposure, but other sources such as residues taken up by plants and soil invertebrates (e.g., earthworms) may also serve as a means of exposure. The following tables (Table 1 and Table 2) provide risk quotients that were calculated based on maximum labeled application rates and the average or typical application rates taken from the Biological and Economic Analysis Division's Quantitative Usage Analysis dated August 9, 2004, as well as label-indicated band widths and row spacing. Granule incorporation efficiency was set at 85 percent (Table 1) or 99 percent incorporation (Table 2). Based on this information, it is evident that risk levels of concern are exceeded even at rates that are less than the application rates allowed by the product labels and at granule incorporation efficiencies approaching 100 percent. Page 15 of 191 ------- Table 1. Ranges of acute risk quotients for small, medium, and large birds and mammals exposed to maximum label rate and typical application rates at 85% incorporation efficiency. Crop (max. rate/typical rate in Ibs ai/acre) Citrus (4.95/3. 7) Cotton (4.05/0.6) Dry Beans (2. 1/1.0) Peanuts (3.0/0.9) Pecans (10. 05/3.1) Potatoes (3. 0/2. 7) Soybeans (3.0/0.7) Sugar beets (4.95/1. 8) Alfalfa (3. 0/NA) Coffee (4.4/NA)1 Sugarcane (3. 0/NA) Tobacco (3. 0/NA) Ornamental (5. 0/NA) Maximum Rate Avian RQs 9-771 71 -6396 29 - 2620 31 -2807 17-1566 33-2963 26-2339 32-2831 5-451 246-22,110 50-4512 20-1805 0.6 - 52 Typical Rate Avian RQs 6-577 11 -948 13 - 1248 9-842 5-483 30 - 2667 6-546 1 1 - 972 not available not available not available not available not available Maximum Rate Mammalian RQs 11-261 93-2161 38-885 41 -948 23 - 529 43-1001 34 - 790 41-956 7-158 332-7738 68-1579 27 - 632 0.8-18 Typical Rate Mammalian RQs 8- 195 14-320 18-422 12-285 7- 163 39-901 8- 184 14-328 not available not available not available not available not available No incorporation assumed based on product label directions. Table 2. Ranges of acute risk quotients for small, medium, and large birds and mammals exposed to maximum label rate and typical application rates at 99% incorporation efficiency. Crop (max. rate/typical rate in Ibs ai/acre) Citrus (4.95/3.7) Cotton (4.05/0.6) Dry Beans (2. 1/1.0) Sorghum (1.05/0.4) Peanuts (3.0/0.9) Pecans (10.05/3.1) Potatoes (3. 0/2.7) Soybeans (3. 0/0. 7) Sugar beets (4.95/1. 8) Sweet potatoes (3.0/1.4) Ornamental (5. 0/NA) Maximum Rate Avian RQs 0.6-52 5-428 2-175 2- 193 2- 188 1- 105 2-198 2- 157 2-190 1-125 0.6 - 52 Typical Rate Avian RQs 0.4-39 0.7-63 0.9-84 0.8-73 0.6-56 0.4-32 2-179 0.4-37 0.7-65 0.7-58 not available Maximum Rate Mammalian RQs 0.8- 17 6- 145 3-59 3-65 2.7 - 64 2-35 3-67 2-53 3-64 2-42 0.8-18 Typical Rate Mammalian RQs 0.6- 13 0.9-21 1 -28 1 -25 0.8-19 0.5- 11 3-60 0.5 - 12 0.9 - 22 0.8-20 not available Page 16 of 191 ------- The potential for mortality to birds has been an area of initial focus, given aldicarb's mode of action and very high acute toxicity. Chronic risk to birds has not yet been quantitatively assessed. However, based on inference from mammalian data, which involved comparing magnitudes of LD50s between the mallard duck (1.0 mg/kg-bw) and rat (0.9 mg/kg-bw) and then using this information together with the chronic information available for the laboratory rat (reproductive NOAEL = 0.7-0.9 mg/kg-bw), the Agency expects that birds (as well as mammals) that survive acute exposure to aldicarb may suffer adverse reproductive (chronic) effects. The Agency is requesting additional data to confirm this hypothesis. While there are some exceedences of acute levels of concern for aquatic species, risk from chronic exposure to aldicarb and its degradates appears to be more significant. The chronic level of concern is exceeded for several uses at maximum application rates and 99 percent incorporation efficiency for freshwater fish and invertebrates, as well as for estuarine/marine fish and invertebrates. However, under typical application rates, these risks for the most part are mitigated. In addition to risk based on exposure estimates from aquatic exposure modeling, there were also exceedences of the Agency levels of concern based on EECs derived from monitoring data. There have been 29 incidents related to aldicarb reported in the Environmental Incident Information System database (reported to the Agency from 1988 to 2005). Of these 29 incidents, 16 were from misuse, 11 were of undetermined use, and 2 were registered agricultural uses. Approximately 17 of the 29 incidents reported included bird kills. Fourteen bird kill incidents were from intentional misuse, and 3 were of undetermined use. Eight of these incidents also resulted in mammal kills (all misuse or undetermined use). When evaluating incident data, it is important to note that currently, no systematic or reliable mechanism exists for the accurate monitoring and reporting of wildlife kill incidents to the Agency. Moreover, before a pesticide incident can be reported or investigated, the dead animals must first be found. In the absence of monitoring following pesticide applications, kills are not likely to be noticed in agro-environments which are generally away form human activity. It is likely that poisoned birds may fly from the use sites, succumbing outside of the area or scavengers may remove carcasses before they can be observed, significantly reducing the chance of detection. Page 17 of 191 ------- IV. Risk Management, Reregistration, and Tolerance Reassessment Decisions A. Determination of Reregistration Eligibility Section 4(g)(2)(A) of FIFRA calls for the Agency to determine, after submission of relevant data concerning an active ingredient, whether or not products containing the active ingredient are eligible for reregi strati on. The Agency has previously identified and required the submission of the generic (technical grade) data required to support reregi strati on of products containing aldicarb as an active ingredient. The Agency has completed its review of these generic data, and has determined that the data are sufficient to support reregi strati on of all products containing aldicarb provided the registrations are amended in a manner consistent with this document. The Agency has completed its review of submitted data and its assessment of the dietary (both food and drinking water), occupational, and ecological risks associated with the use of pesticide products containing the active ingredient aldicarb. Based on these data and public comments received on the Agency's assessments for the active ingredient aldicarb, the Agency has sufficient information on the human health and ecological effects of aldicarb to make a decision as part of the tolerance reassessment process under FFDCA and reregi strati on process under FIFRA, as amended by FQPA. Based on its evaluation of aldicarb, the Agency has determined that products containing the active ingredient aldicarb, unless labeled and used as specified in this document, would present risks inconsistent with FIFRA and FFDCA. Accordingly, should a registrant fail to implement any of the risk mitigation measures identified in this document, the Agency may take appropriate regulatory action to address the risk concerns from the use of aldicarb. If all changes outlined in this document are incorporated into the product labels, then all current risks for aldicarb will be adequately addressed for the purposes of this determination under FIFRA. Once a comprehensive endangered species assessment is completed, further changes to these registrations may be necessary as explained in Section IV.D.4 of this document below. B. Public Comments and Responses Through the Agency's public participation process, EPA worked with stakeholders and the public to reach these regulatory decisions for aldicarb. The Phase 3 public comment period on the risk assessments, opened on May 17, 2006, and the Phase 5 public comment period on the risk assessments and solicitation for additional input to use/usage opened on November 14, 2006. The Agency received comments from several stakeholders (including stakeholders from public interest groups), and the technical registrant, Bayer CropScience. A complete listing of these comments can be found at http://www.regulations.gov./ These comments were reviewed and taken into consideration in preparing the revised risk assessments and their supporting documents, including this aldicarb RED. The comments are available in their entirety in the public docket EPA-HQ-OPP-2005-0163 located on-line at http://www.regulations.gov./. The Agency's responses to substantive comments are available in Page 18 of 191 ------- memoranda in the public docket and the revised assessments available in the public docket reflect these responses. C. Regulatory Position 1. Food Quality Protection Act Findings a. "Risk Cup" Determination As part of the FQPA tolerance reassessment process, EPA assessed the risks associated with aldicarb. The Agency has concluded that, with the risk mitigation measures outlined in this document, the aggregate risk from food and drinking water exposures to aldicarb is within its own "risk cup." The Agency has determined that the human health risks from these combined exposures are within acceptable levels and that, considering every issue other than the cumulative impacts of exposure to other n-methyl carbamate pesticides, the established tolerances for aldicarb, with label amendments and changes as specified in this document, meet the safety standards under the FQPA amendments to Section 408(b)(2)(C) and 408(b)(2)(D) of the FFDCA. In reaching these determinations, EPA has considered the available information on the special sensitivity of infants and children. b. Determination of Safety to U.S. Population (Including Infants and Children) The Agency has determined that there is a reasonable certainty that no harm will result to the general U.S. population, infants, children, or other major identifiable subgroups of consumers, from the use of aldicarb. The safety determination considers factors such as the toxicity, use practices and exposure scenarios, and environmental behavior of aldicarb. In determining whether or not infants and children are particularly susceptible to toxic effects from exposure to residues of aldicarb, the Agency considered the completeness of the hazard database for developmental and reproductive effects, the nature of the effects observed, and other information. The Agency determined it was necessary to retain a 2X FQPA database uncertainty factor for aldicarb residues in the dietary human health risk assessment because magnitude of the brain cholinesterase inhibition was approximately 2-fold greater in the young rat compared to the adult rat at similar acute doses. For specific information relating to the Agency's decision on the FQPA factor, refer to section 3.4 in the February 26, 2007 Human Health Revised Risk Assessment found at http://www.regulations.gov./ c. Endocrine Disrupter Effects EPA is required under the FFDCA, as amended by FQPA, to develop a screening program to determine whether certain substances (including all pesticide active and other ingredients) "may have an effect in humans that is similar to an effect produced by a naturally occurring estrogen, or other such endocrine effects as the Administrator may designate. " Following the recommendations of its Endocrine Disrupter Screening and Testing Advisory Page 19 of 191 ------- Committee (EDSTAC), EPA determined that there were scientific bases for including, as part of the program, androgen and thyroid hormone systems, in addition to the estrogen hormone system. EPA also adopted EDSTAC's recommendation that the Program include evaluations of potential effects in wildlife. When the appropriate screening and/or testing protocols being considered under the Agency's Endocrine Disrupter Screening Program (EDSP) have been developed and vetted, aldicarb may be subjected to additional screening and/or testing to better characterize possible effects related to endocrine disruption. d. Cumulative Risks FFDCA Section 408(b)(2)(D)(v) requires that the Agency consider "available information" concerning cumulative effects of a particular pesticides residues and "other substances that have a common mechanism of toxicity" when considering whether to establish, modify, or revoke a tolerance for pesticide residues in food. EPA considers cumulative effects from pesticides and other substances because low-level exposures to multiple chemical substances causing a common effect by a common mechanism could lead to the same adverse health effect as would a higher level of exposure to each individual substance. Aldicarb is a member of the N-methyl carbamate class of pesticides, which share a common mechanism of toxicity by affecting the nervous system via cholinesterase inhibition. A cumulative risk assessment, which evaluates exposures based on a common mechanism of toxicity, was conducted to evaluate risk from food, drinking water, residential use, and other non-occupational exposures resulting from registered uses of N-methyl carbamate pesticides, including aldicarb. EPA has concluded that the cumulative risks associated with the N-methyl carbamate pesticides are below the Agency's level of concern. For additional information, refer to the document, Revised N-methyl Carbamate Cumulative Risk Assessment, which is available in the EPA docket EPA-HQ-OPP-2007-0935 and on the website, http://www.epa.gov/pesticides/cumulative/. 2. Tolerance Summary The tolerance summary and tolerance reassessment decision is presented for aldicarb in Table 3 below. Currently there are forty tolerances listed in 40 CFR §180.269, 40 CFR §185.150, and 40 CFR §186.150 for residues of aldicarb on raw and agricultural commodities and livestock commodities. The available aldicarb residue chemistry data are considered adequate to reassess most tolerances. The Agency will propose establishing a citrus fruit crop group tolerance of 0.3 ppm. Some commodities with established tolerances must be revised to reflect the correct commodity definition. Additional data are needed to determine appropriate tolerances for residues in/on cottonseed and cotton gin by-products. The established tolerance for residues in peanut hulls should be revoked since this raw agricultural commodity is no longer considered to be significant livestock feed items (OPPTS Series 860.1000, Table 1, 8/96). The Agency recommends classification of residues in livestock Page 20 of 191 ------- commodities under 40 CFR §180.6(a)(3); therefore, tolerances for residues in livestock commodities should be revoked. Table 3. Tolerance Reassessment Summary for Aldicarb and Aldicarb Sulfone and Aldicarb Sulfoxide. Commodity Current Tolerance (ppm) Tolerance Reassessment (ppm) Comment/ [Correct Commodity Definition] Tolerances Listed Under 40 CFR 180.269: Barley, hay Barley, grain Barley, straw Beans (dry) Beets, sugar Beets, sugar, tops Cattle, fat Cattle, mbyp Cattle, meat Coffee beans Cottonseed Goats, fat Goats, mbyp Goats, meat Grapefruits Lemons Limes Oranges Hogs, fat Hogs, mbyp Hogs, meat Horses, fat Horses, mbyp Horses, meat Milk Peanut Peanut, hulls Pecan Potato Sheep, fat Sheep, mbyp Sheep, meat - - - 0.1 0.05 1 0.01 0.01 0.01 0.1 0.1 0.01 0.01 0.01 0.3 0.3 0.3 0.3 0.01 0.01 0.01 0.01 0.01 0.01 0.002 0.05 0.5 0.5 1 0.01 0.01 0.01 3.0 0.02 0.1 0.1 0.05 1 Revoke 0.1 0.1 Revoke 0.3 0.3 0.3 0.3 Revoke 0.05 Revoke Revoke 0.2 Revoke Rotational crop tolerances recommended by HED. [bean, dry, seed] \beet, sugar, roots] [beet, sugar, tops] There is no reasonable expectation of finite residues. [coffee, green bean, import tolerance only] [cotton, undelinted seed] There is no reasonable expectation of finite residues. The registrant has proposed a crop group tolerance of 0.3 ppm for fruit, citrus, group. There is no reasonable expectation of finite residues. Peanut hulls are not considered to be a significant livestock feed item. Revoke The available data reflecting the supported use pattern indicate the established tolerance should be reduced. There is no reasonable expectation of finite residues. Page 21 of 191 ------- Commodity Sorghum, stover (fodder) Sorghum, grain Soybean Sugarcane Sugarcane, fodder Sugarcane, forage Sweet potatoes Wheat, forage Wheat, grain Wheat, straw Wheat, hay Current Tolerance (ppm) 0.5 0.2 0.02 0.02 0.1 0.1 0.1 - - - - Tolerance Reassessment (ppm) Revoke Revoke 0.02 Revoke Revoke Revoke 0.1 1.0 0.02 0.1 3.0 Comment/ [Correct Commodity Definition] soybean, seed [import tolerance only] These commodities are not considered to be significant livestock feed items. sweet potato, root Rotational crop tolerances recommended by HED. Required Tolerances to be Listed Under 40 CFR §180.269 Cotton, gin byproducts — TBDa Tolerances Listed Under 40 CFR §186.150: Citrus pulp, dried Cottonseed, hulls 0.6 0.3 Revoke Revoke Commodity covered by the raw agricultural commodity tolerance. Commodity covered by the raw agricultural commodity tolerance. a Data depicting the magnitude of aldicarb residues of concern in cotton gin byproducts are required in accordance with Table 1 of OPPTS Series 860 Residue Chemistry Test Guidelines, 8/96. D. Regulatory Rationale The Agency has determined that products containing the active ingredient aldicarb are eligible for reregi strati on provided that the risk mitigation measures outlined in this document are adopted and label amendments are made to reflect these measures. The following is a summary of the risk mitigation measures and EPA's rationale for the decision for managing risks associated with the use of aldicarb. Where labeling revisions are warranted, label changes and language are specified in Section V. 1. Human Health Risk Management and Mitigation a. Dietary Risk Mitigation (Drinking Water) As discussed in Section 5.2 of the human health risk assessment (found at http://www.regulations.gov.A), there are risk estimates that exceed EPA's level of concern from aggregate dietary exposure to residents living in the U.S. southeastern coastal plain who consume water from rural ground water wells in specific vulnerable areas. Four ground water scenarios were modeled for aldicarb. The estimated risks at the 99.9 percentile are below the Agency's level of concern for all four scenarios, and for all population ,th Page 22 of 191 ------- subgroups except for infants under the Georgia 300 feet peanut scenario. For all other scenarios, risk are not of concern to the Agency. Therefore, in order to mitigate potential drinking water concerns in the peanut growing regions in the states of Georgia, Alabama, South Carolina, and Florida, an increased well set- back from 300 to 500 feet is required for wells not encased to a depth of 100 feet in vulnerable soils, and a shallow depth to ground water (less than 25 feet). The determination for this buffer was based upon both monitoring data and modeling. The Agency utilized the Natural Resource Conservation Service's (NRCS) criteria for high leaching potential soils for Florida and encourages the technical registrant, Bayer CropScience to use the same criteria when determining vulnerable soils for other states. The Agency's review of "A Retrospective Ground Water Monitoring Study for Aldicarb and Its Metabolites in the Southeastern United States; Mississippi Delta; Texas; California; and Pacific Northwest", dated July 24, 2007, and found at http://www.regulations.gov./ contains the reference to the NRCS criteria. b. Aggregate Risk Mitigation As previously discussed, food and drinking water are below the Agency's level of concern with the mitigation for ground water in the Southeastern states of Alabama, Georgia, South Carolina, and Florida. There are no residential exposures, therefore, no additional mitigation is needed to address aggregate risk. Label changes and language necessary for reregi strati on are specified in Table 5 in Section V. c. Occupational Risk Mitigation As discussed in Section 10 of the human health risk assessment there are no risks of concern to workers performing tasks such as mixing, loading, and applying, based on current labeling. Moreover, since aldicarb is applied to soil when little foliage is present, there are no re- entry risks, given the current Restricted-Entry Intervals (REIs). Therefore, no additional mitigation is necessary. 2. Ecological Risk Management and Mitigation As discussed in the environmental fate and effects risk assessment, ecological risks (direct adverse acute effects) to non-target aquatic and terrestrial organisms are of concern from the use of aldicarb. Additionally, there are chronic risks to aquatic invertebrates (freshwater and estuarine/marine) and freshwater fish. Aldicarb is also a potential ground water, and possibly surface water, contaminant. The ecological risk assessments exhibit RQ values which exceed the various target levels of concern. Risks are much higher, as evidenced by higher RQ values, for terrestrial organisms, especially to birds. In addition to the mitigation outlined below, the Agency intends to require additional confirmatory data which are listed in Table 4 of Section V. a. Terrestrial and Aquatic Organisms Page 23 of 191 ------- Terrestrial The Agency's assessment suggests the potential for acute effects to terrestrial organisms for all application scenarios. Aldicarb is highly toxic to birds, mammals, honeybees, and earthworms; however, due to aldicarb's granular formulation and, in most cases, immediate incorporation into the soil, risks from exposure (undissolved granules left on the surface) to birds and mammals are lessened. In summary, the Agency is concerned with all use patterns for acute effects to birds and mammals. As appropriate under FIFRA, the Agency has weighed the potential risk with the expected benefits of continued use. These conclusions are presented below. Aquatic The Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Adverse effects include reduced survival and reduced reproduction when exposed to aldicarb and/or its metabolites (aldicarb sulfoxide, aldicarb sulfone) as a result of labeled use. Aquatic plants are also subject to adverse effects (reduced survival) when exposed to aldicarb and/or its metabolites (aldicarb sulfoxide, aldicarb sulfone) as a result of labeled use. For potential risk to aquatic species, the chronic level of concern is exceeded for several uses at maximum application rates and 99 percent incorporation efficiency for freshwater fish and invertebrates, as well as for estuarine/marine fish and invertebrates. However, under typical application rates, these risks for the most part are mitigated. Direct application of aldicarb to streams, lakes, and ponds is forbidden by product labels; however, following a rain event, aldicarb may reach aquatic environments from areas of application in sheet and channel-flow runoff, because aldicarb is moderately persistent in terrestrial environments and soluble in water. It is unlikely that aquatic organisms will be directly exposed to granules, both because of the highly soluble nature of the compound (whole granules will dissolve rather than be transported intact) and because of the application methods (directly onto field). Aquatic organisms could also be exposed to aldicarb residues and degradates from ground water that is subsequently discharged into a surface water body. 3. Mitigation Summary and Crop-Specific Analyses The Agency has worked with the technical registrant, Bayer CropScience, to reduce potential exposure of aldicarb to wildlife and aquatic life. Subsequently, Bayer has agreed to voluntarily cancel all current registrations on the following crops: • Coffee • Ornamentals • Pecans • Sugarcane • Sorghum • Tobacco • Alfalfa grown for seed These proposals for cancellation will be announced in the Federal Register (FR). A subsequent FR Notice will finalize the cancellation absent significant comment to change the Page 24 of 191 ------- Agency's position. As part of the Agency's mitigation plan, labels will be amended shortly to remove these uses. To further reduce ecological concerns, the Agency has determined that the label changes (as specified in Table 5 in Section V), as agreed upon by the technical registrant Bayer CropScience, and discussed with stakeholders for specific scenarios and crops, are appropriate and required for reregi strati on eligibility. Listed below are the specific crop use sites/patterns for aldicarb along with corresponding RQs of concern for birds and mammals, stakeholder input on use, alternatives/benefits, mitigation, and EPA's decision regarding reregi strati on eligibility. As a general matter, the Agency has determined that although there is potential for harm to wildlife because of use of aldicarb, that harm will generally be limited in time and space. The Agency also determined that these risks are often outweighed by the benefits expected from use of aldicarb instead of existing alternatives. The Agency was also mindful in this analysis that aldicarb does not pose risks of concerns to pesticide applicators or to farm workers generally. Citrus Current Use Pattern Aldicarb is used on citrus in Florida and Texas only. Application currently consists of a side-dress application and is usually applied along the side of the tree row in furrow and immediately covered with soil. The maximum application rate for use on citrus is currently 4.95 Ibs ai/A. Due to the nature of how aldicarb is applied to citrus (2 inches in depth), the Agency has assumed that 85% of the aldicarb applied is covered with soil, and that 15% may remain on the surface for potential terrestrial organism exposure. Because of acute toxicity and ground water contamination concerns, anyone who applies aldicarb in Florida is required to obtain a permit from the Florida Department of Agriculture and Consumer Services for each application to be made. This permitting process involves the collaborative efforts of the registrant, state officials and growers to ensure that every application of aldicarb is permitted and recorded. For additional information on the aldicarb permitting system in Florida's State Division of Agricultural Environmental Services, please see http://www.flaes.org/temik/. Risks of Concern Assuming 85% Soil Incorporation RQs modeled for birds using maximum rates range from 9 to 771. RQs modeled for birds calculated using typical rates range from 6 to 577. RQs modeled for mammals using maximum rates range from 11 to 261. RQs modeled for mammals using typical rates range from 8 to 195. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement/Input on Citrus During Phases 5 and 6 of the Public Participation Process, in addition to the written comments received from respondents as listed in section IV. B. above, the Agency met with and received comments from Bayer CropScience, the Florida Department of Agriculture and Consumer Services (FDACS), Florida Fruit and Vegetable Association (FFVA), USD A, and many other interested stakeholders with specific knowledge relating to aldicarb use on citrus. Page 25 of 191 ------- These stakeholders have provided additional information regarding aldicarb usage (application methods and rates) and the use of aldicarb in citrus production. In particular, these stakeholders noted that aldicarb appears to effect plant growth, resulting in increased yields when used on citrus. Subsequent meetings, site visits and teleconference calls with Bayer, FDACS, and FFVA have led to the Agency's understanding of the aldicarb permitting process in Florida. Alternatives and Benefits Aldicarb is a recommended insecticide for mites, the Asian Citrus Psyllid (AsCP), and nematode control. Citrus greening is a severe vascular disease transmitted by the Asian citrus psyllid. The psyllid is a relatively new pest that now ranges throughout all the citrus producing areas in Florida and Texas. Greening is a disease that slowly weakens and kills all types of citrus trees, and causes fruit to become lopsided and taste bitter. No cure exists for a tree that contracts the disease. As of 2006, greening had been found in more than 440 different locations in at least 11 Florida counties. Although the AsCP has been found in the Rio Grande Valley of Texas, citrus greening has not been found there at this time. There are several alternatives to aldicarb for control of mites, but there appears to be no feasible alternative to aldicarb for nematode control. Estimated yield losses in Florida without aldicarb are 5 to 10 percent, which corresponds to an annual loss of about $4.6 to $9.3 million for oranges and grapefruit combined. There are no alternatives for control of AsCP, the vector for citrus greening. For nematode control specifically, aldicarb is used to control the citrus and burrowing nematodes although it does not effectively control the burrowing nematode as aldicarb only remains in the shallow part of the root zone. Other nematodes with limited economic importance in Florida are the sting nematode and lesion nematode. EPA's analysis concludes that the absence of aldicarb for use on citrus acreage for controlling both nematodes and other insects can result in yield losses of 5 to 10 percent. Therefore, the cost to growers will be quite high. A 5 to 10 percent yield loss to the "average" grower in Florida corresponds to a $97 to $193 in lost revenue per acre. For the grapefruit grower, a 5 to 10 percent yield loss corresponds to a loss in revenue of $109 to $218 per acre. If the loss to nematodes increased over time, as nematode populations increase, these losses may get worse. The 2000/2001 - 2004/2005 value of orange production in Florida was about $1.1 billion and the value of grapefruit production was approximately $209 million. A 10 percent reduction on the 7 percent of acreage treated with aldicarb would result in a loss of approximately $3.9 to $7.8 million annually to Florida orange growers, and $0.7 to $1.5 million to Florida grapefruit growers. For additional information, refer to the Agency's complete alternative/quantitative impact memo for citrus and the BEAD response to Phase 3 comments for citrus, cotton and pecans which are available in the public docket EPA-HQ-OPP-2005-0163 and located on-line at http://www.regulations.gov/. Mitigation Page 26 of 191 ------- To reduce potential ecological risks, the Agency, in agreement with the technical registrant of aldicarb, has developed several mitigation measures to help address the above mentioned concerns. They include: • Label clarifications to specify application of granules in 3 to 6 furrows beside individual trees, that are 2 inches deep and spaced on approximately 12 inch centers, immediately covering with soil. • Label modifications to help reduce the amount of aldicarb left on the surface of the soil making it less available for the wildlife potentially at risk. For specific label language, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. Additionally, the Agency also acknowledges that, although risks were calculated assuming 85% soil incorporation, actual aldicarb granules available on or just under the soil's surface for potential consumption by birds or mammals is unlikely, given the methods of application including positive displacement (mechanized placement of granules beneath the soil) and lock-and-load containers which minimize potential spillage of product. The Agency has determined that there are benefits of aldicarb use on citrus and, as quantified above, losing its use would involve additional costs to growers. Aldicarb has advantages to citrus growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Aldicarb provides control against insects, including nematodes, in portions of citrus production areas. Because of its long residual activity, in many cases growers can apply one treatment of aldicarb, rather than multiple treatments of other chemicals for equivalent insect control. Also, potential worker risks from multiple foliar applications of these alternative products are not insignificant. Therefore, the use on citrus is eligible for reregi strati on. Cotton Current Use Pattern Aldicarb is used on cotton primarily for control of thrips, although it controls other insect pests. In addition, there is also evidence of aldicarb use to control nematodes on cotton. Aldicarb is applied at-plant or as a side-dress application. The at planting application is administered in the furrow with the cotton seed and immediately covered with soil. Greater than Page 27 of 191 ------- 97% of the use on cotton is this at-plant application. The side-dress application is usually administered after the cotton has emerged from the soil and is applied along the side of the plant row (8 inches from the plants, two or three inches deep) in furrow and immediately covered with soil. The maximum application rate for use on cotton is currently 4.05 Ibs ai/A. Due to the nature of how aldicarb is applied to cotton (at a depth greater than 2 inches), the Agency has estimated that 99% of the aldicarb applied is covered with soil, and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 5 to 428. RQs modeled for birds calculated using typical rates range from 0.7 to 63. RQs modeled for mammals using maximum rates range from 6 to 145. RQs modeled for mammals using typical rates range from 0.9 to 21. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement /Input on Cotton During Phases 5 and 6 of the Public Participation Process, in addition to the written comments received from respondents as listed in section IV. B. above, the Agency met with and received comments from Bayer, the National Cotton Council of America, Cotton Growers Association, Georgia Cotton Commission, USD A, as well as many other interested stakeholders with specific knowledge relating to aldicarb use on cotton. In particular, these stakeholders noted that aldicarb appears to effect plant growth, resulting in increased yields when used on cotton. Alternatives and Benefits The Agency acknowledges that the use of aldicarb has benefits to cotton growers. Although thrips and other insects are targeted, aldicarb is applied to cotton in Texas and the Southeast to control nematodes as well. Based on EPA proprietary data, an annual average of about 1.4 million acre treatments (about 38% of total applications) of aldicarb have targeted nematodes between 2002 and 2006. The state with the most acre treatments against nematodes is Georgia, with an annual average of about 360,000 acres, followed by Texas (about 270,000 acres annually) and North Carolina (about 200,000 acres annually). For thrip control, no one chemical could replace aldicarb, but a combination of chemicals could be used effectively. This combination for insect control was more expensive than aldicarb: the Agency estimates that chemical costs alone would be about $2 per acre higher in Mississippi and $22 per acre higher in California. These chemicals also do not share the advantages of aldicarb which are a longer period of effectiveness and control over multiple pests, including nematodes. If nematodes are considered a target pest, as they are in Texas and the Southeast, growers have fewer alternatives to aldicarb. The best control for nematodes would be 1,3- dichloropropene (1,3-D). The additional cost for replacing aldicarb with 1,3-D, along with the combination of chemicals to provide control of thrips is about $38 per acre. Of that figure, $36 per acre is based on the chemical cost of 1,3-D. If it were assumed that these acres were treated with 1,3-D instead, the additional costs are over $50 million annually. Page 28 of 191 ------- For additional information, refer to the Agency's complete alternative/quantitative impact memo for cotton which is available in the public docket EPA-HQ-OPP-2005-0163 and located on-line at http://www.regulations.gov/. Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: • At-plant application rate will be reduced to a maximum of 1.5 Ibs ai/A. This equates to a 63% reduction in rate as compared to the current label. • Side-dress application rate will be reduced to 2.1 Ibs ai/A. This equates to a 30% reduction as compared to the current label. • Per-season application rate is limited to 3.6 Ibs ai/A. This equates to a 63% reduction as compared to the current label. • Label specifications to clarify the depth at which aldicarb is applied. Additionally, modifications in label language to help reduce the amount of aldicarb left on the surface of the soil, making it less available for wildlife potentially at risk. For specific label language, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. The Agency has determined that there are benefits of aldicarb use on cotton and, as specified above, losing its use would involve additional costs to growers, some of which can be quantified directly. Aldicarb has advantages to cotton growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Aldicarb provides control of insects, including nematodes, in portions of cotton production areas. Alternative pesticides, which can be used to control insect pests (e.g., thrips), are not effective in controlling multiple pests. Aldicarb also provides protection for a longer period of time than any of the alternatives. As stated above, because of its long residual activity, in many cases growers can apply one treatment of aldicarb, rather than multiple treatments of other chemicals for equivalent insect control. Also, potential worker risks from multiple foliar applications of these alternative products are not insignificant. Therefore, the use on cotton is eligible for reregi strati on. Page 29 of 191 ------- Dry Bean Current Use Pattern Aldicarb application to dry beans currently consist of an at-plant application. The at- planting application is administered in the furrow with the dry bean seed and immediately covered with soil at a depth greater than 2 inches. The maximum application rate for use on dry bean is currently 2.1 Ibs ai/A. Due to the nature of how aldicarb is applied to dry bean, the Agency has estimated that 99% of the aldicarb applied is covered with soil and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 2 to 175. RQs modeled for birds calculated using typical rates range from 0.9 to 84. RQs modeled for mammals using maximum rates range from 3 to 59. RQs modeled for mammals using typical rates range from 1 to 28. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement/Input for Dry Bean During Phases 5 and 6 of the Public Participation Process, in addition to the written comments from respondents as listed in section IV. B. above, the Agency has met with and received comments from Bayer CropScience, USD A, as well as many other interested stakeholders with specific knowledge relating to aldicarb use on dry bean. Alternatives and Benefits The Agency understands that aldicarb use on dry bean is of benefit to dry bean growers in the states of Idaho, Michigan, Oregon and Washington. Aldicarb use in dry bean production is a valuable tool for controlling aphids, leafhoppers, the Mexican bean beetle, and several species of nematodes. There are both foliar and seed treatment alternatives, such as thiamethoxam, but only aldicarb provides season long control at planting, and growers do not have to spray multiple times. In Michigan, aldicarb is also used to control the root-lesion nematode, which can cause 10% yield reduction and is present in 50% of the dry bean acreage if left uncontrolled. On the acreage with nematodes that is not treated, growers expect lower yields. As with other crops, the main value of aldicarb as an insecticide is that a single at-plant treatment will protect the seedling and young plant for several weeks from attack by nematodes and several insect pests, some of which are vectors of plant viruses. Although alternatives (such as esfenvalerate, dimethoate, propargite, and others) exist for use against all insect pests controlled by aldicarb, it would likely take at least two applications of foliar insecticides to provide the same level of protection afforded by an at-plant aldicarb treatment. Where nematodes are also a problem, it would also take a pre-plant application with a soil fumigant, such as 1,3-D. While aldicarb alternatives exist, the Agency believes that the economic impact on dry bean growers of shifting to such alternatives for nematode control are likely to be cost prohibitive, in which case the likely result of loss of aldicarb would be that growers would face a financial penalty from reduced yield because of nematodes. Page 30 of 191 ------- Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: • Geographically restricting the use to Idaho, Michigan, Oregon, and Washington. • Modifications in label language to help reduce the amount of aldicarb left on the surface of the soil, thereby making it less available for wildlife potentially at risk. For the label language modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. The Agency has determined that there are benefits of aldicarb use on dry bean and that losing its use would involve additional costs to growers. Aldicarb has advantages to dry bean growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the use on dry bean is eligible for reregi strati on. Peanut Current Use Pattern Aldicarb is applied when peanuts are planted, or can be used as a split treatment, where aldicarb is applied at-plant and also applied later in the season when the plants are forming pegs, which develop into peanuts. This application is referred to as "at-pegging". Aldicarb is generally used to control nematodes and thrips on peanuts, primarily in the southern States, as well for the suppression of leafhoppers and spider mites. To better understand the potential risk and resulting mitigation, these two use patterns are discussed in more detail below. At Planting Aldicarb is applied to peanuts at planting for protection against thrips and several species of nematodes (e.g. root-knot, lesion, stubby root, sting). For thrips control the granules are applied in the seed furrow and then covered with soil. The peanut seed is then planted into the treated zone. When used for nematode control, aldicarb granules are applied in a 6 to 12 inch band over an open furrow and covered with soil to a depth of 2 to 4 inches. Due to the nature of Page 31 of 191 ------- how aldicarb is applied to peanuts at planting (at a depth greater than 2 inches), the Agency has estimated that 99% of the aldicarb applied is covered with soil and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern for the At-Plant Application Method Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 2 to 188. RQs modeled for birds calculated using typical rates range from 0.6 to 56. RQs modeled for mammals using maximum rates range from 2.7 to 64. RQs modeled for mammals using typical rates range from 0.8 to 19. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. At Pegging Aldicarb can also be applied later in the season when the plants are forming pegs (at- pegging), which develop into peanuts. In this case, aldicarb is typically applied at the initiation of pegging, in a 12 to 18 inch band over the peanut row. Unlike other aldicarb application practices, soil incorporation does not occur because the plant has already formed pegs (which develop into peanuts) just under the surface of the soil. Attempts to incorporate the granules would damage the roots of the plants and any pegs that have formed. Due to the nature of how aldicarb is applied to peanuts at pegging (without any mechanical means of soil incorporation), the Agency has assumed that 100% of the aldicarb applied remains on the surface for potential terrestrial organism exposure. Risks of Concern for the At-Pegging Application Method RQs modeled for birds using maximum rates range from 31 to 2,807. RQs modeled for birds calculated using typical rates range from 9 to 842. RQs modeled for mammals using maximum rates range from 41 to 948. RQs modeled for mammals using typical rates range from 12 to 285. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement/Input for Peanuts During Phases 5 and 6 of the Public Participation Process, in addition to the written comments from respondents listed in section IV. B. above, the Agency has met with and received comments from Bayer, the National Peanut Board, Florida Fruit and Vegetable Association, Florida Department of Agriculture and Consumer Services, USD A, and other interested stakeholders with specific knowledge relating to aldicarb use on peanuts. Alternatives and Benefits For the at-plant use of aldicarb, early season control of nematodes may be achieved with a pre-plant soil fumigation with 1,3-D; however, it would require one or more other insecticides (primarily ethoprop) to address other pests. Therefore, for the at-plant use of aldicarb, there are no chemical or non-chemical alternatives that can provide both insect and nematode control on peanuts during the first month after plant emergence. For the at-pegging use of aldicarb, multiple treatments of the alternatives may be required, and none of those alternatives also control nematodes. Because of aldicarb's ability to control both nematodes and insect pests, alternatives to aldicarb will consist of at least one Page 32 of 191 ------- insecticide application for thrips control and one nematicide application in areas where both pests exist. Based upon data reviewed by the Agency, withholding the at-pegging aldicarb treatment caused a yield decrease of 56%. Applying this loss to dollars per acre, it is estimated that without the aldicarb at-pegging use, revenues would fall from $290 to $227 per acre. Another important factor considered by the Agency was that nematode damage to peanut plants does not stop with yield damage, but also causes damage to the peanuts that are harvested. The Agency is aware that, potentially, this damage could correspond to a discount of about 10 cents per pound. Therefore, revenue loss from reduced quality could be as high as losses from reduced yields. In conclusion, without aldicarb, costs to growers from the yield losses due to nematode damage alone are estimated to exceed $15 million a year in Georgia, and up to $22 million a year nationwide. It is clear to the Agency that without the use of aldicarb there would be substantial costs to growers who are currently using aldicarb approximately 30-45 days after plant (at- pegging); up to $300 per acre based upon data from field trials performed in Georgia. For additional information, refer to the Agency's complete alternative/quantitative impact memo for peanuts which is available in the public docket EPA-HQ-OPP-2005-0163 and located on-line at http://www.regulations.gov/. Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: • For the split-season, at-pegging use of aldicarb, application must be made late in the afternoon or early evening and immediately followed by irrigation, and completed within 24 hours which will help dissolve granules thereby making them unavailable for wildlife. • Label clarifications for post-emergent use: apply granules in a band 12 to 18 inches wide on the row and into the plant canopy. Ensure that plant foliage is dry prior to application. Dislodge granules from foliage by suitable means that will not damage the plant. • Label clarifications to ensure that at-planting applications are done over an open furrow which is 4 to 6 inches in width, known as "T-band" applications. • For the specific label language for the application modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of Page 33 of 191 ------- exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. The Agency has determined that there are benefits of aldicarb use on peanut (both the at- planting and at-pegging use) and that losing its use would involve additional costs to growers, as quantified above. Aldicarb also has advantages to peanut growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the use on peanut is eligible for reregi strati on. Potato Current Use Pattern Aldicarb is currently registered for use on potatoes only in Oregon, Idaho, Washington, Montana, northern Florida, and parts of Utah and Nevada. Aldicarb is used primarily to control green peach aphid, Colorado potato beetle, and also provides some protection against several species of nematodes. Other pests controlled include leafhoppers and flea beetles. Aldicarb application to potatoes typically consists of an at-plant or pre-plant application using positive displacement equipment. Aldicarb granules are applied within the row furrow and buried along with the seed potato at planting to a depth of four to eight inches. The potato plant absorbs aldicarb through its roots, and once in the plant, the residual activity of aldicarb protects the treated plant against pest nematodes and insects for six to eight weeks. The maximum application rate for use on potato is currently 3.0 Ibs ai/A. Due to the nature of how aldicarb is applied to potatoes (at a depth of 4 to 8 inches), the Agency has estimated that 99% of the aldicarb applied is covered with soil, and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 2 to 198. RQs modeled for birds calculated using typical rates range from 2 to 179. RQs modeled for mammals using maximum rates range from 3 to 67. RQs modeled for mammals using typical rates range from 3 to 60. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement and Input for Potatoes During Phases 5 and 6 of the Public Participation Process, in addition to the written comments received from respondents listed in section IV. B. above, the Agency has met with and received comments from Bayer, the National Potato Council, USDA and other interested stakeholders with specific knowledge relating to aldicarb use on potatoes. These stakeholders have provided additional information regarding aldicarb usage (application methods and rates) and the need for aldicarb use to remain in potato production. In particular, these stakeholders noted that aldicarb appears to effect plant growth, resulting in increased yields when used on potatoes. Alternatives and Benefits Page 34 of 191 ------- The Agency has determined that the benefits to growers of aldicarb use on potatoes are very high in certain states (Washington, Oregon, Idaho and Florida) and that losing its use would involve substantial costs to growers. There are also concerns with the potential for resistance if aldicarb were not available. Several nematodes, including the root-knot nematode, the root lesion nematode, and the stubby root nematode are major pests of potatoes and have wide host ranges, making management with crop rotation difficult and relatively ineffective, although they can be controlled by fumigants. Aldicarb may also be used to reduce root-knot nematode populations that remain high after soil fumigation. There are several alternatives for the use of aldicarb on potatoes, but none of these will be an adequate substitute. Even if aldicarb is applied specifically to target nematodes, it is inappropriate to ignore the beneficial effect of controlling insect pests, as well. For this reason, an analysis of alternatives to aldicarb considered multiple chemicals so that both nematodes and insects can be targeted. Because of aldicarb's ability to control both nematodes and insect pests, alternatives to aldicarb will consist of multiple chemicals used to target multiple pests. The estimates of additional costs for using alternatives to aldicarb range from $77 - 257 per acre in the Pacific Northwest, and $77 - 218 in Florida. It is clear that alternatives will involve significant costs to growers who are currently using aldicarb. For nematode control, the Agency believes that the most likely alternative to aldicarb is the use of a fumigant, such as 1,3-D, although additional chemicals would be required to control insect pests. While synthetic insecticides remain the most effective means for its control, resistance by the Colorado potato beetle to all classes of insecticides has been documented in many U.S. potato-producing regions. Widespread and locally diverse esfenvalerate and phosmet resistance was detected in all counties in southern and eastern Idaho. For additional information, refer to the Agency's complete alternative/quantitative impact memo for potatoes which is available in the public docket EPA-HQ-OPP-2005-0163 and located on-line at http://www.regulations.gov/. Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop the mitigation below to help address the above mentioned concerns: • Modifications in label language to clarify the manner in which aldicarb is applied to potatoes, and immediately covering with soil. For the label language modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules Page 35 of 191 ------- that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. As discussed above, the Agency has determined that there are benefits of aldicarb use on potatoes and that losing its use would involve substantial costs to growers. Aldicarb also has advantages to potato growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the Agency finds the use on potatoes eligible for reregi strati on. Soybean Current Use Pattern Aldicarb is applied to soybean at planting. Aldicarb granules are applied within the row furrow and buried along with the soybean seed at planting. The maximum application rate for use on soybean is currently 3.0 Ibs ai/A. Due to the nature of how aldicarb is applied to soybean (at a depth greater than 2 inches), the Agency has estimated that 99% of the aldicarb applied is covered with soil, and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 2 to 157. RQs modeled for birds calculated using typical rates range from 0.4 to 37. RQs modeled for mammals using maximum rates range from 2 to 53. RQs modeled for mammals using typical rates range from 0.5 to 12. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement/Input for Soybean During Phases 5 and 6 of the Public Participation Process, in addition to the written comments from respondents listed in section IV. B. above, the Agency has met with and received comments from Bayer, USDA and soybean growers in Georgia, Minnesota and South Carolina with specific knowledge relating to aldicarb use on soybeans. Alternatives and Benefits Aldicarb is used as a nematicide in late maturity soybean varieties grown in Georgia, North Carolina, and South Carolina. Because there are few late maturity soybean varieties that are resistant to nematodes (root-knot, reniform, and Columbian lance), growers of such varieties depend more on aldicarb than growers of early maturity soybean varieties, for which nematode resistant varieties exist. In South Carolina, approximately 60% of the soybean acreage has nematode problems. The only available aldicarb alternative for nematode control, 1,3-D, is too expensive for soybean production. Without aldicarb, soybean growers in the affected states would stop growing soybeans or shift to very long rotations with other crops. Aldicarb, therefore, is a critical tool for soybean growers. Mitigation Page 36 of 191 ------- To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: • Limiting the use to the following states: Georgia, North Carolina, and South Carolina. • Reducing the application rate from 3.0 Ibs ai/A to 1.5 Ibs ai/A. This equates to a 50% reduction when compared to the current label. • Modifications in label language to help reduce the amount of aldicarb in use and left on the surface of the soil (i.e., clarifications in the use of positive displacement technology), making it less available for the wildlife potentially at risk. For the label language modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. The Agency has determined that there are benefits of aldicarb use on soybeans in Georgia, North Carolina and South Carolina, and that losing its use would involve additional costs to growers. Aldicarb also has advantages to soybean growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the Agency finds the use on soybeans eligible for reregi strati on. Sugar Beet Current Use Pattern Aldicarb application to sugar beets currently consists of an at-plant and a side-dress application. The at planting application is administered with the sugar beet seed and immediately covered with soil. The side-dress application is usually administered after the sugar beet has emerged from the soil and is applied along the side of the plant row in furrow and immediately covered with soil. Aldicarb is used to manage sugar beet root maggot, nematode, particularly sugar beet cyst nematode, beet leafminer, beet leafhopper, aphids, flea beetles, wireworms, and cutworms, primarily in Idaho. The maximum application rate for use on sugar beet is currently 4.95 Ibs ai/A. Due to the nature of how aldicarb is applied to sugar beet (at a depth greater than 2 inches), the Agency has Page 37 of 191 ------- estimated that 99% of the aldicarb applied is covered with soil, and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 2 to 190. RQs modeled for birds calculated using typical rates range from 0.7 to 65. RQs modeled for mammals using maximum rates range from 3 to 64. RQs modeled for mammals using typical rates range from 0.9 to 22. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement and Input for Sugar Beet During Phases 5 and 6 of the Public Participation Process, in addition to the written comments from respondents listed in section IV. B. above, the Agency has met with and received comments from Bayer, American Sugarbeet Growers Association, Western Sugar Cooperative, NYSSA-NAMPA Beet Growers Association, USD A, and other interested stakeholders with specific knowledge relating to sugar beet production. These stakeholders have provided additional information regarding aldicarb usage (application techniques and application rates) and the need for aldicarb use to remain in sugar beet production. In particular, these stakeholders also noted that aldicarb appears to effect plant growth, resulting in increased yields when used on sugar beet. Alternatives and Benefits The Agency understands that aldicarb use on sugar beet is of great benefit to the sugar beet industry, particularly in Western states, and that losing its use would involve substantial costs to growers in those states. The available usage data indicate 75 percent of the sugar beet acreage in Idaho, Montana, Oregon and Washington was treated with aldicarb in 2005. Aldicarb is used primarily to manage sugar beet root maggot and nematodes on sugar beets, which are major pests of sugar beets. If left uncontrolled, yield losses from sugar beet root maggot can be as much as 80%. Yield losses from nematodes can be equally as devastating to a sugar beet crop. For insect control, sugar beet root maggot is a major pest of sugar beets and aldicarb effectively controls both adults and larvae. If aldicarb were not available for the control of sugar beet maggot, growers would likely use terbufos which is not as effective on both the adult fly and larvae. Additionally, EPA has required, and the terbufos registrant has agreed, to a phased approach that will ultimately reduce sales of terbufos by 55% by 2008. Other pesticides available and used to a lesser extent than aldicarb and terbufos include phorate, chlorpyrifos, and carbofuran. Phorate controls larvae but is mostly used in areas with low pest pressure. Carbofuran was available in Idaho and Oregon under 24c labels to control larvae but does not have a long residual value. Further, the Agency expects to initiate action in the near future to cancel all uses of carbofuran. Esfenavalerate and zeta-cypermethrin control adult flies but another insecticide would need to be used to control larvae. For nematodes, only fumigants are available for control besides aldicarb but are significantly more expensive than aldicarb. Page 38 of 191 ------- For nematode control specifically, only fumigants are available as alternatives, such as 1,3-D. A major disadvantage to using 1,3-D is the chemical cost relative to aldicarb (see below). Another disadvantage of using 1,3-D is that growers must wait for the soil to warm before fumigating, and then wait for the gas to dissipate before planting, shortening the growing season. Growers would also need to consider the added costs due to different application equipment using 1,3-D. The estimates of costs for using aldicarb alternatives are more than $20 per treatment per acre to control the sugar beet root maggot and approximately $88 to control nematodes. For comparison, the cost of aldicarb is about $40 per acre. This assumes that the alternatives are equally efficacious. Although the alternatives for control of the sugar beet root maggot appear to be less expensive, other considerations may preclude their use. If the alternatives are less effective than aldicarb, yield or quality impacts could also occur. In addition, if multiple pests targeted by aldicarb are present, multiple chemicals/applications may be needed to achieve a similar level of control. For additional information, refer to the Agency's response to Phase 5 comments found EPA-HQ-OPP-2005-0163 and located on-line at http://www.regulations.gov/. Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: • Limit use to the following states: California, Colorado, Idaho, Montana, Nebraska, Oregon, Washington and Wyoming. • Modifications in label language to help reduce the amount of aldicarb left on the surface of the soil (i.e., clarifications in the use of positive displacement technology) and making it less available for the wildlife potentially at risk. For the label language modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. As discussed above, the Agency has determined that there are benefits of aldicarb use on sugar beets in certain states (California, Colorado, Idaho, Montana, Nebraska, Oregon, Washington and Wyoming) and that losing its use would involve substantial costs to growers. Aldicarb also has advantages to sugar beet growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected Page 39 of 191 ------- infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the Agency finds the use on sugar beet eligible for reregi strati on. Sweet Potato Current Use Pattern Aldicarb application to sweet potato typically consists of an at-plant application using positive displacement equipment. Aldicarb granules are applied within the row furrow and buried along with the seed piece at planting to a depth of four to eight inches. The sweet potato plant absorbs aldicarb through its roots and once in the plant, the residual activity of aldicarb protects the treated plant against pest nematodes and insects for six to eight weeks. The maximum application rate for use on sweet potato is currently 3.0 Ibs ai/A. Due to the nature of how aldicarb is applied to sweet potatoes (at a depth of 4 to 8 inches), the Agency has estimated that 99% of the aldicarb applied is covered with soil, and that only 1% remains on the surface for potential terrestrial organism exposure. Risks of Concern Assuming 99% Soil Incorporation RQs modeled for birds using maximum rates range from 1 to 125. RQs modeled for birds calculated using typical rates range from 0.7 to 58. RQs modeled for mammals using maximum rates range from 2 to 42. RQs modeled for mammals using typical rates range from 0.8 to 20. Additionally, although RQs are low, the Agency's assessment also suggests the potential for adverse effects to aquatic invertebrates and fish. Stakeholder Involvement and Input for Sweet Potato During Phases 5 and 6 of the Public Participation Process, in addition to receiving written comments from respondents listed in section IV. B. above, the Agency has met with and received comments from Bayer, USD A, and other interested stakeholders relating to aldicarb use on sweet potato. These stakeholders have provided additional information regarding aldicarb usage (application and application rates) and the need for aldicarb use to remain in sweet potato production. Alternatives and Benefits The Agency understands that aldicarb use on sweet potatoes is of benefit in the states of Louisiana and Mississippi and that losing aldicarb's use would involve substantial cost to growers. It is a very important tool for sweet potato growers where nematode pressure is present. Alternatives include 1,3-D, oxamyl and ethoprop, but they do not, however, control a particular pest, the reniform nematode, as well as aldicarb. This nematode causes smaller, misshapen sweet potatoes that cannot be marketed and aldicarb is the only tool which completely controls this pest species. Not controlling nematodes may result in 100% yield loss, and partial control can yield poor quality sweet potatoes, which if sold on the processing market, will only bring 10% of the prices of marketable sweet potatoes. Mitigation To reduce potential ecological risks, the Agency has directed, and the registrant has agreed, to develop several mitigation measures to help address the above mentioned concerns. They include: Page 40 of 191 ------- • Limit application of aldicarb to: Louisiana and Mississippi only. • Addition of label language specifying granules be applied in a 12-inch band within an open furrow and covered immediately during bed forming by mechanically hilling 8 to 10 inches. • Slight modifications in label language to help reduce the amount of aldicarb left on the surface of the soil (i.e., clarifications in the use of positive displacement technology) and making it less available for the wildlife potentially at risk. For the label language modifications, please refer to Table 5 in Section V. EPA Decision Aldicarb has the potential to cause adverse effects to birds, mammals and aquatic species. However, due to the physical properties of aldicarb's granules (e.g., color, size, and solubility) and how aldicarb is soil incorporated, actual exposure of potentially affected populations to aldicarb granules is uncertain and may be overestimated. Potential risks to birds and mammals would be limited primarily to the treated fields where wildlife, if present, could ingest granules that are not incorporated in the soil and that have not yet dissolved. Therefore, the extent of exposure, both spatially and temporally, is expected to be limited. The Agency recognizes, however, that actual exposure of wildlife to aldicarb is uncertain. As discussed above, the Agency has determined that there are benefits of aldicarb use on sweet potatoes in certain states (Louisiana and Mississippi) and that losing its use would involve substantial costs to growers. Aldicarb also has advantages to sweet potato growers for which EPA cannot estimate dollar values, such as simplicity of management, confidence in the level of control in the face of unexpected infestation, and cost effectiveness when considering the full range of pests and duration of control. Therefore, the Agency finds the use on sweet potatoes eligible for reregi strati on. 4. Other Labeling Requirements In order to be eligible for reregi strati on, additional aldicarb information needs to be included in the labeling of all end-use products containing aldicarb. Uses and use patterns need to be clarified as indicated in Table 5 below to reflect and better describe actual use patterns for aldicarb. For the specific label statements and a list of additional data requirements necessary to confirm this decision, refer to Section V of this IRED document. 5. Threatened and Endangered Species Considerations The Agency's screening level risk assessment for endangered and threatened species concluded that use of aldicarb has direct adverse effects on listed species in the following taxonomic groups: terrestrial invertebrates, birds, terrestrial phase amphibians, reptiles, mammals, freshwater fish, freshwater invertebrates, estuarine/marine invertebrates, and estuarine/marine fish. There is also the potential for indirect adverse effects for listed species in multiple taxonomic groups that are dependent upon species that do experience direct adverse effects. These findings are based solely on EPA's screening level assessment and do not constitute "may affect" findings under the Endangered Species Act. Page 41 of 191 ------- The Agency has developed the Endangered Species Protection Program to identify pesticides whose use may cause adverse impacts on threatened and endangered species and to implement mitigation measures that address these impacts. The Endangered Species Act requires Federal agencies to ensure that their actions are not likely to jeopardize listed species or adversely modify designated critical habitat. To analyze the potential of registered pesticide uses that may affect any particular species, EPA uses basic toxicity and exposure data developed for REDs and considers it in relation to individual species by evaluating important ecological parameters, pesticide use information, the geographic relationship between specific pesticide uses and species locations, and biological requirements and behavioral aspects of the particular species. When conducted, this species-specific analysis will take into consideration any risk mitigation measures that are being implemented at the time as a result of this RED. Following this future species-specific analysis, a determination that there is a likelihood of potential effects to a listed species or its critical habitat may result in further limitations on use of aldicarb, other measures to mitigate any potential effects, or consultations with the Fish and Wildlife Service and/or the National Marine Fisheries as appropriate. If the Agency determines use of aldicarb "may affect" listed species or their designated critical habitat, EPA will employ the provisions in the Services regulations (50 CFR Part 402). Until a species-specific analysis is completed, the risk mitigation measures being implemented through this RED (e.g., rate reductions and geographic restrictions) will reduce the likelihood that endangered and threatened species may be exposed to aldicarb at levels of concern. EPA is not requiring specific aldicarb label language at the present time relative to threatened and endangered species. If, in the future, specific measures are necessary for the protection of listed species, the Agency will implement them through the Endangered Species Protection Program. EPA is currently engaging in informal consultations with the Fish and Wildlife Service and the National Marine Fisheries Service, which is a part of the National Oceanic and Atmospheric Administration. This means that the Agencies are working together to conduct a full endangered species assessment for aldicarb, which is separate from this RED. The likelihood of potential impacts to endangered species will need to be assessed for all counties in which: 1) crops registered for aldicarb use are grown; and 2) contain habitat for at least one listed species. Page 42 of 191 ------- V. What Registrants Need to Do The Agency has determined that products containing the active ingredient aldicarb are eligible for reregi strati on provided that the risk mitigation measures outlined in this document are adopted and label amendments are made to reflect these measures. The Agency intends to issue DCIs for generic (technical grade) data and product-specific data. Generally, registrants will have 90 days from receipt of a generic DCI to complete and submit response forms or request time extension and/or waiver requests with a full written justification. The DCIs will include specific requirements and instructions on how to respond. Table 4 below presents the additional generic data the Agency intends to require for aldicarb to confirm the decision that products containing the active ingredient aldicarb are eligible for reregi strati on. For product- specific DCIs, registrants will have eight months from receipt of the DCI to submit data and to submit amended labels. In order for products containing the active ingredient aldicarb to be eligible for reregi strati on, all product labels must be amended to incorporate the specific changes and language presented in Table 5 below. Table 5 also describes how the required language should be incorporated. A. Manufacturing-Use Products 1. Additional Generic Data Requirements The generic database supporting the reregi strati on of aldicarb has been reviewed and determined to be substantially complete. However, EPA is requiring the following additional data to confirm the decisions presented in this RED. The Agency intends to issue a generic DCI for this data. Table 4. Data requirements for the reregistration of aldicarb. Data Requirement Magnitude of the Residue in Plant Studies Data depicting the magnitude of aldicarb residues of concern in cotton gin byproducts are required in accordance with Table 1 of OPPTS Series 860 Residue Chemistry Test Guidelines, 8/96. Terrestrial Plant Toxicity - Tier 1 (seedling emergence) Terrestrial Plant Toxicity - Tier 1 (vegetative Vigor) Aquatic Plant toxicity Test - using Lemna spp. - Tiers I and II Avian Reproduction Study in Quail Avian Reproduction Study in Duck UV/Visible Aborption Comparative Cholinesterase Assay New OPPTS Guideline Number (GLN) 860.1500 850.4100 850.4150 850.4400 850.2300 830.7050 Special Study 2. Labeling for Manufacturing-Use Products To ensure compliance with FIFRA, labeling for all manufacturing-use products (MUPs) should be revised to comply with all current EPA regulations, PR Notices, and applicable policies. The MUP labeling should bear the specific language presented in Table 5 below. Page 43 of 191 ------- B. End-Use Products 1. Additional Product-Specific Data Requirements Section 4(g)(2)(B) of FIFRA calls for the Agency to obtain any needed product-specific data regarding the pesticide after a determination of eligibility has been made. The registrant must review previous data submissions to ensure they meet current EPA acceptance criteria and if not, commit to conduct new studies. If a registrant believes that previously submitted data meet current testing standards, then the study MRID numbers can be cited according to the instructions in the Requirement Status and Registrations Response Form provided for each product. The Agency intends to issue a separate product-specific DCI outlining specific data requirements. 2. Labeling for End-Use Products To be eligible for reregi strati on, labeling changes are necessary to implement measures outlined in Section IV above. The specific changes and language are presented in Table 5 below. Generally, conditions for the distribution and sale of products bearing old labels/labeling will be established when the label changes are approved. However, specific existing stocks time frames will be established case-by-case, depending on the number of products involved, the number of label changes, and other factors. Page 44 of 191 ------- Table 5. Summary of Required Labeling Changes for Aldicarb Products. Description Amended Labeling Language for Manufacturing Use Products Placement on Label For all Manufacturing Use Products "Only for formulation into an insecticide/nematicide for the following uses: citrus, cotton, dry bean, peanuts, potatoes, soybean, sugar beets, sweet potatoes." "Only formulation into low dust granular products such as products that use a vinyl binder coating to adhere the aldicarb to either a corn cob grit or a gypsum substrate. Binding aldicarb to clay substrate is prohibited." Directions for Use Note to Registrant This product may not be used to formulate products for use on alfalfa grown for seed, coffee, ornamentals, pecans, sorghum, sugarcane, and tobacco. One of these statements may be added to a label to allow reformulation of the product for a specific use or all additional uses supported by a formulator or user group "This product may be used to formulate products for specific uses not listed on the MP label if the formulator, user group, or grower has complied with U.S. EPA submission requirements regarding support of such uses." "This product may be used to formulate products for any additional uses not listed on the MP label if the formulator, user group, or grower has complied with U.S. EPA submission requirements regarding support of such uses." Directions for Use Environmental Hazards Statements "This pesticide is extremely toxic to birds and mammals. This pesticide is toxic to fish and aquatic invertebrates. Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in accordance with the requirements of a National Pollution Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge. Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage treatment plant authority. For guidance contact your State Water Board or Regional Office of the EPA." Precautionary Statements Page 45 of 191 ------- End Use Products Intended for Occupational Use Restricted Use Pesticide "Restricted Use Pesticide" "Due to acute oral toxicity and to ground water contamination. For retail sale to and use only by Certified Applicators or persons under the direct supervision of a Certified Applicator, and only for those uses covered by the Certified Applicator's certification." This statement must appear at the very top of the label's front panel [see 40 CFR 156.10(j)(2)(i) for more information]. No other wording or symbols should appear above the RUP statement. PPE Requirements Established by the RED1 for low- dust granular formulations that are packaged in closed loading and application systems (e.g., Lock 'nLoad, Smartbox) "Personal Protective Equipment (PPE)" "Some materials that are chemical-resistant to this product are" (registrant inserts correct chemical-resistant material). "If you want more options, follow the instructions for category" [registrant inserts A,B,C,D,E,F,G,orH] "on an EPA chemical-resistance category selection chart." "All loaders, applicators, and other handlers must wear; > long-sleeved shirts and long pants, > shoes plus socks. In addition, loaders and handlers cleaning equipment or spills must wear: > chemical-resistant gloves made of any waterproof material, and > chemical-resistant apron. See engineering controls section for additional requirements." Immediately following/below Precautionary Statements: Hazards to Humans and Domestic Animals. PPE Requirements Established by the RED1 for granular "Personal Protective Equipment (PPE)" "Some materials that are chemical-resistant to this product are" (registrant inserts correct Immediately following/below Precautionary Page 46 of 191 ------- low- dust formulations that are not packaged in a closed loading and application system. chemical-resistant material). "If you want more options, follow the instructions for category" [registrant inserts A,B,C,D,E,F,G,or H] "on an EPA chemical-resistance category selection chart." "All loaders, applications and other handlers must wear at a minimum: > coveralls over long-sleeved shirts and long pants, > chemical-resistant gloves made of any waterproof material, > chemical-resistant footwear plus socks, and > protective eyewear. In addition, loaders and handlers cleaning equipment or spills must wear: > chemical-resistant apron, and > a NIOSH-approved respirator with a dust/mist filter with MSHA/ NIOSH approval number prefix TC-21C or any N, R, P, or HE filter." "See engineering controls for additional options." Statements: Hazards to Humans and Domestic Animals. User Safety Requirements "Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry." Precautionary Statements: Hazards to Humans and Domestic Animals immediately following the PPE requirements. Engineering Controls for granular low- dust formulations that are packaged in closed loading and application systems (e.g., Lock 'n Load, Smartbox) "Engineering Controls" "This product is formulated into a (registrant inserts the trade name of the closed system in which the product is marketed, such as Lock 'NLoad or SmartBox) system that meets the definition of a closed loading and application system in the Worker Protection Standard for Agricultural Pesticides [40 CFR 170.240(d)(4)]. Loaders and applicators using the closed- system packaging must: ~ wear the personal protective equipment required in the PPE section of this labeling for loaders during loading, and — wear the personal protective equipment required in the PPE section of this labeling for Precautionary Statements: Hazards to Humans and Domestic Animals (Immediately following PPE and User Safety Requirements.) Page 47 of 191 ------- applicators during applying, and ~ be provided, have immediately available, and use in an emergency, such as a broken package, spill, or equipment breakdown: chemical-resistant gloves, chemical-resistant apron, chemical-resistant footwear, protective eyewear, and aNIOSH-approved respirator with a dust/mist filter with MSHA/NIOSH approval number prefix TC-21C or any N R, P, or HE filter." Engineering Controls: Enclosed Cabs for Ground Applicators "Engineering Control Options for Enclosed Cabs: Applicators using an enclosed cab that meets the definition in the Worker Protection Standard for Agricultural Pesticides [40 CFR 170.240(d)(5)] may wear reduced personal protective equipment, provided they: ~ wear a long-sleeve shirt, long pants, shoes, and socks ~ are provided, have immediately available, and use in an emergency, such as a broken package, spill, or equipment breakdown: chemical-resistant gloves, chemical-resistant apron, chemical-resistant footwear, protective eyewear, and aNIOSH-approved respirator with a dust/mist filter with MSHA/NIOSH approval number prefix TC-21C or any N R, P, or HE filter. ~ take off any PPE that was worn in the treated area before reentering the cab, and ~ store all such PPE in a chemical-resistant container, such as a plastic bag, to prevent contamination of the inside of the cab." Precautionary Statements: Hazards to Humans and Domestic Animals (Immediately following PPE and User Safety Requirements.) User Safety Recommendations "User Safety Recommendations" "Users should wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet. Users should remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. Users should remove PPE immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing." Precautionary Statements under: Hazards to Humans and Domestic Animals immediately following Engineering Controls (Must be placed in a box.) Environmental "This pesticide is extremely toxic to birds and wildlife. Birds feeding on exposed granules Precautionary Statements Page 48 of 191 ------- Hazards may be killed. Cover or immediately soil incorporate granules spilled during loading." "This pesticide is toxic to fish and aquatic invertebrates. Run-off from treated areas may be hazardous to fish in neighboring areas. Do not apply directly to water, to areas where surface water is present or to inter-tidal areas below the mean high water mark. Do not contaminate water when disposing of equipment wash waters." "This product is toxic to bees exposed to direct treatment. Do not apply this product while bees are actively visiting the treatment area." "Aldicarb is known to leach through soil into ground water under certain conditions as a result of labeled use. Use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in ground-water contamination." "See use directions for individual crops for additional ground water restrictions. See soil tables." immediately following the User Safety Recommendations Environmental Hazards Statements Required by the RED and Agency Label Policies "Under the Endangered Species Act, it is a Federal Offense to use any pesticide in a manner that results in the death of a member of an endangered species. This Act protects Attwater's Greater Prairie Chicken in the Texas counties of Aransas, Austin, Brazoria, Colorado, Galveston, Goliad, Harris, Refugio, and Victoria. Prior to making applications in these counties, the user must determine that this species is not located in or immediately adjacent to the area to be treated. If the user is in doubt whether or not the above named endangered species may be affected, he should contact either the regional U.S. Fish & Wildlife Service office (Endangered Species Specialist) or personnel of the State Fish and Game office." Precautionary Statements Page 49 of 191 ------- Restricted-Entry Interval for products with directions for use within scope of the Worker Protection Standard for Agricultural Pesticides (WPS) "Do not enter or allow worker entry into treated areas during the restricted entry interval (REI) of 48 hours." "Exception: If the product is soil-incorporated or soil-injected, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated." Agricultural Use Requirements Box Early Entry Personal Protective Equipment for products with directions for use within the scope of the WPS "PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water, is: * coveralls worn over long-sleeve shirt and long pants, * chemical-resistant gloves made of any waterproof material, * chemical-resistant footwear plus socks, and * protective eyewear." Direction for Use Agricultural Use Requirements box Double notification requirement "Notify workers of the application by warning them orally and by posting warning signs at entrances to treated areas." Agricultural Use Requirements Box General Application Restrictions "Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application." Place in the Direction for Use directly above the Agricultural Use Box. Other Application Restrictions for all products "Application must be made using a motorized ground spreader. Application using aircraft, handheld, backpack spreaders, or push-type spreaders is prohibited." Directions for Use Associated with the Specific Use Pattern Other Application Restrictions for products with directions for use on Citrus CITRUS The maximum single application rate is 4.95 Ibs ai/A. Do not make more than one application per tree per use season. Do not allow livestock to graze in treated area. The Preharvest Interval is 30 days. Directions for Use Associated with the Specific Use Pattern Page 50 of 191 ------- (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) All application must be made with granular applicators which use Positive Displacement Metering Units. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. Granules must be place into bottom of the seed furrow and immediately covered with at least 2 inches of soil by mechanical means. For Mature Citrus Trees: "apply in a band along the drip line on both sides of tree row. Apply granules in 3 to 6 furrows that are 2 to 3 inches deep and spaced on approximately 12 inch centers. Immediately cover with soil by mechanical means. The width of each band should equal 1/4 the tree row spacing." OR For furrow irrigation applications to mature citrus, "apply granules 2 to 3 inches deep in the irrigation furrow using 2 shanks per furrow." For Immature Citrus Trees (1-2 years old): "0.3 oz ai/tree (do not exceed 4.95 Ibs ai/acre). Apply granules in a furrow beside individual trees and cover with at least 2 inches of soil." Other Application Restrictions for products with directions for use on Cotton (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) COTTON The maximum single at-plant application rate is 1.5 Ibs ai/A. The maximum single side-dress (post-emergence) application rate is 2.1 Ibs ai/A. Do not exceed a total of 3.6 Ibs ai/A per year. Do not make more than one at-plant application and one post-emergence application per crop. Do not apply within 90 days of harvest. Do not feed cotton forage to livestock or allow livestock to graze in treated area. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. At Planting: "Apply granules in the seed furrow and immediately cover with soil by mechanical means. Directions for Use Associated with the Specific Use Pattern Page 51 of 191 ------- OR If rate exceeds 1.05 Ibs ai/A on 40 inch rows, "apply granules in a 4 to 6 inch band (T- band) over open seed furrow and immediately cover by mechanical means." At First Squaring: "Apply side dress granules in a furrow that is 6 to 10 inches to one or both sides of the plant row to a depth of 2 to 3 inches." Other Application Restrictions for products with directions for use on Dry Bean (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) DRY BEANS (other than soybeans) For use in Oregon, Washington, Idaho, and Michigan only. Do not exceed a total of 2.1 Ibs ai/A/season. Do not make more than one application per crop. Do not apply within 90 days of harvest. Do not feed green forage, hay, or straw to livestock. Do not allow livestock to graze in treated areas before harvest. Do not use green pods as food for humans. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. Immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. For all applications, except for where furrow irrigation is used: "Apply granules in seed furrow and immediately cover with soil by mechanical means. OR Apply in a furrow that is 2 to 3 inches to the side of seed row and 2 to 3 inches deep in seed furrow and immediately cover with soil by mechanical means. OR Apply granules on a 4 to 6 inch band over open furrow and immediately cover with soil by mechanical means. Plant into treated zone." When furrow irrigation is used: "apply granules 3 to 4 inches deep and 3 inches from the seed row on the water furrow side and immediate cover with soil by mechanical means." Directions for Use Associated with the Specific Use Pattern Other Application Restrictions for PEANUT Do not exceed a total of 3.0 Ibs ai/A/season Directions for Use Associated with the Page 52 of 191 ------- products with directions for use on Peanut (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) Do not harvest within 90 days of application. Do not hog-off treated fields. Do not allow livestock to graze in treated areas before harvest. Do not feed hay or vines to livestock. Post-emergence applications can only be used in fields where overhead irrigation is available. Do not make more than one application per crop in states other than Alabama, Florida, Georgia, North Carolina, Oklahoma, Texas, and Virginia. Do not make the split application to Spanish peanuts or other short season varieties (a minimum of 90 days is required between pegging applications and harvest). If aldicarb is applied to peanuts in AL, GA and SC and a vulnerable soil is present and the water table is less than 25 feet below ground surface, do not apply within 500 feet of a drinking water well unless wells are either cased to 100 feet below ground level or a minimum of 30 feet below the water table. If it is not known whether the water table is greater than 25 feet below ground surface, assume that the water table is less than 25 feet below ground surface. If aldicarb is applied to peanuts in Florida and a vulnerable soil is present (see soils listed below), and the water table is less than 25 feet below ground surface, do not apply within 500 feet of a drinking water well unless wells are either cased to 100 feet below ground level or a minimum of 30 feet below the water table. In Florida, it is the responsibility of the applicator to document the construction of wells claimed not to be shallow. This must consist of: (a) a copy of the well completion report issued by the appropriate water management district; or (b) a statement certified as to accuracy by a licensed well contractor. The U.S.D.A. Natural Resources Conservation Service which serves your county can tell you if the soils on your farm fall within the following types of vulnerable soils. If it is not known whether the water table is greater than 25 feet below ground surface, assume that the water table is less than 25 feet below ground surface. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. Thrips At Planting: "Apply granules in seed furrow and immediately cover with soil by mechanical means to a depth of 2 to 4 inches." Nematodes At Planting: "Apply granules in a 4-6 inch band over open seed furrow (T- Specific Use Pattern Page 53 of 191 ------- band) and immediately cover with soil by mechanical means to a depth of 2 to 4 inches. OR Apply granules in a 6 to 12 inch band and immediately cover with soil by mechanical means to a depth of 2 to 4 inches. Plant seed into treated zone." At Pegging: "Apply granules in a band 12 to 18 inches wide on the row and into the plant canopy. Ensure that plant foliage is dry prior to application. Dislodge granules from foliage by suitable means that will not damage the plant. Application must be made late in the afternoon or early evening, immediately followed by irrigation, and completed within 24 hours unless rainfall is received." Other Application Restrictions for products with directions for use on Potato (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) POTATOES For use only in the states of Florida, Idaho, Montana, Oregon, and Washington; in Utah in the counties of Beaver, Boxelder, Cache, Carbon, Davis, Duchesne, Iron, Millard, Plute, Salt Lake, Sanpete, Sevier, Ulntah, Utah, Wasatch, Washington, and Weber; and in Nevada in the counties of Humboldt and Pershing. Do not exceed 3.0 Ibs ai/A/season. All applications must be made with Positive Displacement Applicators such as Horstine Microband® or Gandy PDM® or with other Positive Displacement Applicators approved under the Bayer CropScience Equipment Certification Program. The applicator must be certified through the Bayer CropScience Stewardship program. Do not harvest within 100 days of application for potatoes grown in Florida and within 150 days of application for potatoes grown in the Pacific Northwest (Idaho, Montana, Oregon, Washington, and certain counties in Nevada and Utah). Do not apply after planting. Do not make more than one application per crop. If replanting is necessary, do not retreat the second crop with (registrant insert brand name). Do not allow livestock to graze in treated areas before harvest. In state other than Florida, do not use furrow irrigation on aldicarb-treated potatoes. Do not use this product on potatoes in any state other than those immediately listed above. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. Immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. Directions for Use Associated with the Specific Use Pattern Page 54 of 191 ------- At Planting: "Apply granules in a 6 inch band and immediately cover with 4 to 8 inches of soil by mechanical means. Plant seed pieces into treated zone. OR Apply granules in furrow with seed piece. Immediately cover with 4 to 8 inches of soil by mechanical means." Other Application Restrictions for products with directions for use on Soybean (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) SOYBEAN For use on soybeans grown only in Georgia, North Carolina, and South Carolina. Do not exceed a total of 1.5 Ibs ai/A/season. Do not make more than one application per crop. Do not apply within 90 days of harvest. Do not allow livestock to graze in treated areas before harvest. Do not feed green forage, hay or straw to livestock. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. Immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. At Planting: "Apply granules in seed furrow and immediately cover with soil by mechanical means. OR If rate exceeds 0.9 Ibs ai/A on 30 inch rows, "Apply a 4 to 6 inch band over open seed furrow and immediately cover with soil by mechanical means." Directions for Use Associated with the Specific Use Pattern Other Application Restrictions for products with directions for use on Sugar Beet (Note: The maximum allowable application SUGAR BEETS For use only in California, Colorado, Idaho, Montana, Nebraska, Oregon, Washington, and Wyoming. The total maximum rate per crop cycle is 4.95 Ibs ai/A. Do not make more than one at-planting application and two post-emergence applications per crop. Do not apply within 90 days of harvest. If tops are to be fed to livestock, do not apply within 120 days of harvest." Directions for Use Associated with the Specific Use Pattern Page 55 of 191 ------- rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) Do not use tops as food to humans. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. Nematodes At Planting: "Apply granules in a 4 to 6 inch band and immediately cover with soil by mechanical means. Plant seed into or above treated zone. OR where furrow irrigation is employed for seed germination, drill granules 3 to 4 inches deep and 3 inches from seed row on water furrow side." Aphids. Leafminers and Leafhoppers At Planting: "Drill granules 1 to 3 inches below seedline." Sugar Beet Root Maggot At Planting: "Apply granules in a 2 to 3 inch band over seed row and immediately cover with soil by mechanical means. OR where furrow irrigation is employed for seed germination, drill granules 2 inches deep and 2 inches from seed row on water furrow side. For the 7 Ib. rate, apply granules in a 1 to 2 inch band in front of the press wheel as the furrow is closing." Post-emergence: "Apply granules to both sides of plant row and immediately cover with soil by mechanical means. OR for furrow irrigation side-dress granules 4 to 8 inches to water furrow side of plant row at furrow depth. Irrigate soon after application. Apply within 60 days after planting." Other Application Restrictions for products with SWEET POTATOES For use in Louisiana and Mississippi only. Maximum application rate is 3 pounds ai/A/crop. Directions for Use Associated with the Specific Use Pattern Page 56 of 191 ------- directions for use on Sweet Potato (Note: The maximum allowable application rate and maximum allowable seasonal rate must be listed as pounds or gallons of formulated product per acre, not just as pounds active ingredient per acre.) Do not make more than one application per crop. Do not harvest within 120 days of application. Do not feed sweet potato vines to livestock. Application must be made with granular applicators which use Positive Displacement Metering Units. Apply granules in a 12-inch band open furrow. Immediately cover granules by mechanical hilling soil at least 8 to 10 inches. If it is not known whether the water table is greater than 25 ft below ground surface, assume that the water table is less than 25 feet below ground surface. Immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. Pre-plant or At Planting: "Apply granules in a 12-inch band open furrow or soil surface and cover immediately during bed forming by mechanically hilling up 8 to 10 inches. Place transplant in center of treated zone." PPE that is established on the basis of Acute Toxicity of the end-use product must be compared to the active ingredient PPE in this document. The more protective PPE must be placed in the product labeling. For guidance on which PPE is considered more protective, see PR Notice 93-7. Page 57 of 191 ------- Appendix A. Aldicarb Uses and Use-Patterns Eligible for Reregistration SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) CITRUS (Oranges, Grapefruit, Lemons, and Limes only) 30 day(s) preharvest interval. All application must be made with granular applicators which use Positive Displacement Metering Units. Apply only while wearing prescribed protective gloves. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to inter-tidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic disallowable: CA, CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Curry County, OR. Foliar Soil in-furrow treatment /Soil shanking treatment /Soil treatment. Granule applicator. 4.95 Ibai/A G 4.95 Ibai/A 4.95 Ib ai/cc 1/1 cc NS 48 h COTTON (UNSPECIFIED) 90 day(s) preharvest interval. Apply only while wearing prescribed protective gloves. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Page 58 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) Do not apply when drift is likely to occur. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not feed forage to livestock or allow livestock to graze in treated areas. Do not graze dairy animals in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or Humbolt counties in CA or in Curry County, OR. At planting Band treatment /Soil band treatment /Soil drill treatment /Soil in-furrow treatment. Granule applicator. At first squaring Soil sidedress treatment. Granule applicator. Squaring through early bloom Soil in-furrow treatment /Soil sidedress treatment. 1.5 Ibai/A 2.1 Ibai/A 2.1 Ibai/A G G G 3.6 Ibai/A 3.6 Ib ai/cc 3.7 Ibai/A 3.6 Ib ai/cc 3.8 Ibai/A 3.6 Ib ai/cc 2/cc 2/cc 2/cc NS NS NS 48 h 48 h 48 h Page 59 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) Granule applicator. LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) BEANS, DRIED- TYPE 90 day(s) preharvest interval. Apply only while wearing prescribed protective gloves. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not feed green forage, hay, or straw to livestock. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Do not use green pods as food for humans. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic allowable: ID, MI, OR, WA only. Geographic disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or Humbolt counties in CA or in Curry County, OR. At planting Soil band treatment /Soil in- furrow treatment. Granule applicator. 2.1 Ibai/A G 2.1 Ibai/A 2.1 Ib ai/cc 1/1 cc NS 48 h PEANUTS (UNSPECIFIED) 90 day(s) preharvest interval. Do not make more than one application per crop in states other than AL, FL, GA, NC, OK, TX, and VA. Do not make split application to Spanish peanuts or other short season varieties. Page 60 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) Apply only while wearing prescribed protective gloves. Do not allow livestock to graze treated areas before harvest. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not apply when drift is likely to occur. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not feed hay or vines to livestock. Do not feed treated hay or vines to livestock. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not hog down treated fields. Do not store or use in or around the home or home garden. Drift and runoff may be hazardous to aquatic organisms in neighboring areas. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restrictions: If aldicarb is applied to peanuts in AL, GA and SC and a vulnerable soil is present and the water table is less than 25 feet below ground surface, do not apply within 500 feet of a drinking water well unless wells are either cased to 100 feet below ground level or a minimum of 30 feet below the water table. If it is not known whether the water table is greater than 25 feet below ground surface, assume that the water table is less than 25 feet below ground surface. If aldicarb is applied to peanuts in Florida and a vulnerable soil is present (see soils listed below), and the water table is less than 25 feet below ground surface, do not apply within 500 feet of a drinking water well unless wells are either cased to 100 feet below ground level or a minimum of 30 feet below the water table. In Florida, it is the responsibility of the applicator to document the construction of wells claimed not to be shallow. This must consist of: (a) a copy of the well completion report issued by the appropriate water management district; or (b) a statement certified as to accuracy by a licensed well contractor. The U.S.D.A. Natural Resources Conservation Service which serves your county can tell you if the soils on your farm fall within the following types of vulnerable soils. If it is not known whether the water table is greater than 25 feet below ground surface, assume that the water table is less than 25 feet below ground surface. Incorporate to a minimum depth of 2 inches. Keep out of lakes, streams, and ponds. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not Page 61 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) At planting Soil band treatment /Soil in- furrow treatment. Granule applicator At pegging Soil band LIMITATIONS Max. Single Appl. Rate Form Code(s) plant corn, cucurbits, or fi Geographic disallowable' Humbolt counties in CA c o 3 lbai/A 1.5 lbai/A G G Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) uiting vegetabes within 8 months after the last application. CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or )r in Curry County, OR. o 3 lbai/A o J Ib ai/cc 3 lbai/A 3 Ib ai/cc 2/cc 2/cc NS NS 48 h 48 h Geographic allowable: AL, FL, GA, NC, OK, TX, and VA only. Do not make split application to Spanish peanuts or other short season varieties. Ensure that plant foliage is dry prior to application. Dislodge granules from foliage by suitable means that will not damage the plant. Irrigate immediately after application and complete within 24 hours unless rainfall is received Page 62 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) POTATO 100 day(s) preharvest interval for potatoes grown in FL. 150 day(s) preharvest interval for potatoes grown in ID, MT, OR, WA, and certain counties in NV (Humbolt and Pershing) and UT (Beaver, Boxelder, Cache, Carbon, Davis, Duchesne, Iron, Millard, Plute, Salt Lake, Sanpete, Sevier, Uintah, Utah, Wasatch, Washington, and Weber). All application must be made with granular applicators which use Positive Displacement Metering Units. Apply only while wearing prescribed protective gloves. Do not allow livestock to graze treated areas before harvest. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic allowable: FL, ID, MT, OR, WA, and certain counties in NV (Humbolt and Pershing) and UT (Beaver, Boxelder, Cache, Carbon, Davis, Duchesne, Iron, Millard, Plute, Salt Lake, Sanpete, Sevier, Uintah, Utah, Wasatch, Washington, and Weber). Geographic disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or Humbolt counties in CA or in Curry County, OR. At planting Soil band treatment /Soil drill treatment /Soil in-furrow treatment. Granule applicator. 3 Ibai/A G 3 Ibai/A 3 Ib ai/cc 1/cc NS 48 h Page 63 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) SOYBEANS (UNSPECIFIED) 90 day(s) preharvest interval. Apply only while wearing prescribed protective gloves. Do not allow livestock to graze treated areas before harvest. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not apply to any body of water. Do not apply when drift is likely to occur. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not feed green forage, hay, or straw to livestock. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic allowable: GA, NC, and SC only. Geographic disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or Humbolt counties in CA or in Curry County, OR. At planting Soil band treatment /Soil drill treatment /Soil in-furrow treatment. Granule applicator /Not on label. 1.5 Ibai/A G 1.5 Ibai/A 1.5 Ib ai/cc 1/cc NS 48 h SUGAR BEET 120 day(s) preharvest interval if the tops are to be fed to livestock. 90 day(s) preharvest interval. Page 64 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) LIMITATIONS Max. Single Appl. Rate Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) Apply only while wearing prescribed protective gloves. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not apply when drift is likely to occur. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Do not use tops as food for humans. Endangered species restriction. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not plant corn, cucurbits, or fruiting vegetabes within 8 months after the last application. Geographic allowable: CA, CO, ID, MT, ME, OR, WA, and WY only. Geographic disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or Humbolt counties in CA or in Curry County, OR. Preplant Soil band treatment /Soil drill treatment. Granule applicator. At planting Soil band treatment /Soil drill treatment /Soil in-furrow treatment /Soil incorporated treatment by irrigation /Soil sidedress 4.95 Ibai/A 4.95 Ibai/A G G 4.95 Ibai/A 4.95 Ib ai/cc 4.95 Ibai/A 4.95 Ib ai/cc 3/cc 3/cc NS NS 48 h 48 h Page 65 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) treatment. Granule applicator. Postemergence Soil in-furrow treatment /Soil incorporated treatment by irrigation /Soil sidedress treatment /Soil treatment. Granule applicator. LIMITATIONS Max. Single Appl. Rate 4.05 Ibai/A Form Code(s) G Max. Seasonal Rate 4.95 Ibai/A 4.95 Ib ai/cc Max. # Apps/ cc &yr 3/cc MRI NS REI 48 h PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) SWEET POTATO 120 day(s) preharvest interval. All application must be made with granular applicators which use Positive Displacement Metering Units. Apply only while wearing prescribed protective gloves. Do not allow the feeding of vines or grazing of foliage by livestock. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not apply this product to fields within 50 feet of wells used for drinking water. More restrictive setbacks may apply. Do not apply when drift is likely to occur. Do not contaminate water by cleaning of equipment or disposal of equipment wash waters. Do not contaminate water by cleaning of equipment or disposal of waste. Do not contaminate water, food or feed. Do not contaminate water, food, or feed by storage or disposal. Do not feed treated vines to livestock. Do not graze dairy animals in treated areas. Do not graze livestock in treated areas. Do not graze meat animals in treated areas. Do not store or use in or around the home or home garden. Endangered species restriction. For terrestrial uses, do not apply directly to water or to areas where surface water is present or to intertidal areas below the mean high water mark. Ground water restriction. Incorporate to a minimum depth of 2 inches. Proper ventilation required. Runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. This pesticide is toxic to aquatic invertebrates. This product is highly toxic to birds, fish, and other wildlife. For all applications, immediately deep-disc any spills at row ends or elsewhere to ensure the granular is completely covered with a layer of soil. 10 months rotational/plant back crop restriction with the following exceptions: Do not plant wheat, barley, bulb crops, or brassica crops within 6 months after the last application. Do not Page 66 of 191 ------- SITE NAME Application Equipment, Timing, and Type (for any Reg.# at any rate) At planting Soil band treatment. Granule applicator. LIMITATIONS Max. Single Appl. Rate plant corn, c Geographic Geographic Humbolt coi 3 Ib ai/A Form Code(s) Max. Seasonal Rate Max. # Apps/ cc &yr MRI REI PHI/PGI/PSI Use Limitations (May not apply to all Reg. #s) ucurbits, or fruiting vegetabes within 8 months after the last application. allowable: LA and MS only. disallowable: CT, MA, ME, NH, NJ, NY, PA, RI, VT, WI, or in Del Norte or unties in CA or in Curry County, OR. G 3 Ib ai/A 3 Ib ai/cc 1/cc NS 48 h Page 67 of 191 ------- Appendix B. Table of Generic Data Requirements and Studies Used to Make the Reregistration Decision Guide to Appendix B Appendix B contains listing of data requirements which support the reregi strati on for active ingredients within case #0140 (aldicarb) covered by this RED. It contains generic data requirements that apply to aldicarb in all products, including data requirements for which a "typical formulation" is the test substance. The data table is organized in the following formats: 1. Data Requirement (Column 1). The data requirements are listed in the order in which they appear in 40 CFR part 158. The reference numbers accompanying each test refer to the test protocols set in the Pesticide Assessment Guidance, which are available from the National technical Information Service, 5285 Port Royal Road, Springfield, VA 22161 (703) 487-4650. 2. Use Pattern (Column 2). This column indicates the use patterns for which the data requirements apply. The following letter designations are used for the given use patterns. A. Terrestrial food B. Terrestrial feed C. Terrestrial non-food D. Aquatic food E. Aquatic non-food outdoor F. Aquatic non-food industrial G. Aquatic non-food residential H. Greenhouse food I. Greenhouse non-food J. Forestry K. Residential L. Indoor food M. Indoor non-food N. Indoor medical O. Indoor residential 3. Bibliographic Citation (Column 3). If the Agency has acceptable data in its files, this column list the identify number of each study. This normally is the Master Record Identification (MIRD) number, but may be a "GS" number if no MRID number has been assigned. Refer to the Bibliography appendix (Appendix D) for a complete citation of the study. Page 68 of 191 ------- New Guideline Number Old Guideline Number Requirement Use Pattern Bibliographic Citation(s) Product Chemistry 830.1550 830.1600 830.1620 830.1670 830.1700 830.1750 830.1800 830.6302 830.6303 830.6304 830.6313 830.6314 830.6315 830.6316 830.6317 830.6319 830.6320 830.7000 830.7050 830.7100 830.7200 830.7220 830.7300 830.7370 830.7550 830.7840 830.7950 61-1 61-2a 61-2b 61-2b 62-1 62-2 62-3 63-2 63-3 63-4 63-13 63-14 63-15 63-16 63.17 63-19 63-20 63-12 N/A 63-18 63-5 63-6 63-7 63-10 63-11 63-8 63-9 Product Identity and Composition Start. Mat. & Mfg. Process Description of Production Process Discussion of Impurities Preliminary Analysis Certification of limits Analytical Method Color Physical State Odor Stability temp and ions Oxidation and Reduction Flammability Explodability Storage stability Miscibility Corrosion Characteristics PH UV/Visible absorption Viscosity Melting point/melting range Boiling point/range Density Dissociation Constants in Water Partial Coefficient, shake flask method Water Solubility Vapor Pressure A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C 00152095 letter dated 8/12/86 00152095 00152095 00152095 00152095 00152095 letter dated 8/12/86 00152095 letter dated 8/12/86 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 Data Gap 00152095 00152095 00152095 00152095 00152095 00152095 00152095 00152095 Environmental Fate 835.2120 835.2240 161-1 161-2 Hydrolysis Photodegradation Water A,B,C A,B,C aldicarb: 00053377 00096547 00102011 00102048 00102057 00102072 00102065 sulfoxide: 00102066 aldicarb: 00102067 00102068 42498201 Page 69 of 191 ------- 835.2410 835.4100 835.4400 835.4300 835.1240 835.6100 835.6200 161-3 162-1 162-3 162-4 163-1 164-1 164-2 Photodegradation Soil and Air Aerobic Soil Metabolism Anaerobic Aquatic Metabolism Aerobic Aquatic Metabolism Leaching/ Adsorption/Desorption Terrestrial Field Dissipation Aquatic Field Dissipation A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C aldicarb: Waived sulfoxide: Waived sulfone: Waived aldicarb: 00029989 00093641 00096968 00102050 00101915 00102051 00102054 00035365 00101934 00102071 00053366 00080820 00093640 00093642 43805702 44005001 sulfone: 00053370 aldicarb: 43805701 sulfoxide: 45592110 sulfone: 45592111 aldicarb: N/A sulfoxide: 45592108 sulfone: 45592109 aldicarb: 00053380 00053381 00053385 00101915 00101939 00102079 42498202 sulfoxide: 43560301 sulfone: 43560302 aldicarb: 00036313 00053364 00068252 00080815 00101910 00101923 00101935 00101937 00102064 00101936 00101968 00102061 00102078 aldicarb: 00094799 00101940 Environmental Fate - Drinking Water Monitoring Data 835.7100 166-1 Prospective Ground water Monitoring Study A,B,C 46793702 46793703 46793704 46793705 46793706 Ecological Effects 850.2100 850.2200 850.2200 850.2300 850.2300 850.1075 850.1075 850.1010 71-la 71-2a 71-2b 71-4a 71-4b 72-la 72-lc 72-2a Avian Oral LD50 Quail/Duck Avian Dietary LC50 Quail Avian Dietary LC50 Quail Avian Reproduction Quail Avian Reproduction Duck Freshwater Fish LC50 Bluegill (warm water) Freshwater Fish LC50 Rainbow trout (cold water) Freshwater Invertebrate LC50 Daphnia magna A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C BOWOAL02io7398 (Beavers/1979) 00102132 1096727 (Beavers/1979) 096397 0022923 (Hill/1975) Data Gap Data Gap 40098001 3503 (Mayer and Ellersieck 1986) 40098001 (Mayer and Ellersieck 1986) Ace #096683 (Vilkas/1977) Foranetal. 1985 Page 70 of 191 ------- 850.1045 850.1025 850.1035 850.1400 850.1400 850.1300 850.1350 850.4100 850.4150 850.4400 850.3020 N/A 72-3a 72-3b 72-3c 72-4a 72-4a 72-4b 72-4b 123-2 N/A N/A 122-2 141-1 N/A Estuarine/Marine Fish LC50 Estuarine/Marine Mollusk EC50 Estuarine/Marine Shrimp EC50 Fish Early Life-Stage (freshwater) Fish Early Life-Stage (estuarine/marine) Aquatic Invertebrate Life-Cycle (freshwater) Aquatic Invertebrate Life-Cycle (estuarine/marine) Aquatic Plant Growth Terrestrial Plant Toxicity (seedling emergence) Terrestrial Plant Toxicity (vegetative vigor) Aquatic Plant Growth (Tier 2) Honey Bee Acute Contact LD50 OECD, Section 2 #207 Earthworm Acute Toxicity Test A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C 40228401 (USEPA/1986) 40228401 (USEPA/1986) 00066341 (USEPA/1981) 40228401 (USEPA/1986) 44598601 (Pickering and Gilliam 1982) 66341 (USEPA/1981) 44598601 (Pickering and Gilliam 1982) 66341 (USEPA/1981) 00066341 (USEPA/1981) 00066341 (USEPA/1981) 40228401 (USEPA/1986) Data Gap Data Gap Data Gap 00036935 (Atkins/1975) Mosleh (2003) Residue Chemistry 860.1300 860.1300 860.1340 860.1340 860.1340 860.1360 171-4a 171-4b 171-4c 171-4d 171-4d 171-4m Nature of Residue in Plants Nature of Residue in Livestock Residue Analytical Method plant Residue Analytical Method livestock Residue Analytical Method water/fish Multiple Residue Methods A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C 00053358 00053364 00053366 00053368 00085455 00101929 00101930 00101931 00101977 00101996 00102009 00102178 42436602-42436606 43902401 00053371 00053373 00080697 00080813 00101933 00101967 00159570 43084101 00025167 00036315 00069739 00069740 00101973 00101978 00101992 00101993 00101997 00101998 00101999 00102004 00102005 00102007 00104553 00135031 00140487 42436501 00101924 00101990 00101991 N/A PAM Volume I Section 302 and 401 Page 71 of 191 ------- 860.1380 860.1400 860.1460 860.1480 860.1480 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 171-4e 171-4h 171-41 171-4J 171-4J 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k Storage Stability Data Nature and Magnitude of the Residue in Water, Fish and Irrigated Crops Magnitude of the Residue in Food Handling Establishments Milk and the Fat, Meat, and Meat Byproducts of Cattle, Goats, Hogs, Horses, and Sheep Eggs and the Fat, Meat, and Meat Byproducts of Poultry Magnitude of Residue (potato) Magnitude of Residue (sugar beet, roots) Magnitude of Residue (sweet potato) Magnitude of Residue (sugar beet, tops) Magnitude of Residue (beans, dry) Magnitude of Residue (soybean, seed and aspirated grain fractions) Magnitude of Residue (soybean, forage and soybean, hay) Magnitude of Residue (grapefruit) Magnitude of Residue (lemon) Magnitude of Residue (lime) Magnitude of Residue (orange) Magnitude of Residue (pecan) A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C PP#OF1008 PP#9F0798 PP#3F1414 pp#7E1996 PP#6F1953 PP#7F1995 PP#8F2107 PP#8F0637 PP#9F2201 PP#6E1792 PP#8F2096 FAP#6H5108 00159571 42467301 42467302 43844701 4384240143299005 43299006 N/A N/A 00053372 00101967 PP#3F1414 00053373 00080815 00102012 00102014 00102172 00164424 42827802- 42827804 43299002 43385001 00035368 00035369 00101966 PP#7F1995 42722301 00035368 00035369 00101966 00135031 00135031 N/A 00102129 00148971 00102129 00102129 00036313 00102075 00102115 00102174 42004401 42016901 43110601 00140487 Page 72 of 191 ------- 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1500 860.1520 860.1520 860.1520 860.1520 860.1520 860.1520 860.1520 860.1520 860.1520 860.1850 860.1900 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-4k 171-41 171-41 171-41 171-41 171-41 171-41 171-41 171-41 171-41 165-1 165-2 Magnitude of Residue (sorghum, grain and aspirated grain fractions) Magnitude of Residue (sorghum, forage and sorghum, stover (fodder)) Magnitude of Residue (coffee, bean) Magnitude of Residue (cotton, seed and cotton gin by-products) Magnitude of Residue (peanut, nutmeat and peanut, hulls) Magnitude of Residue (sugarcane) Magnitude of Residue (tobacco) Processed Food/Feed (citrus) Processed Food/Feed (coffee, bean) Processed Food/Feed (cottonseed) Processed Food/Feed (peanut) Processed Food/Feed (potato) Processed Food/Feed (sorghum) Processed Food/Feed (soybean) Processed Food/Feed (sugar beet) Processed Food/Feed (sugarcane) Confined rotational crops Field rotational crops A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C PP#8F2107 PP#8F2107 00102024 PP#7F1953 00101977 00102061 PP#7F1995 PP#9F0798 Data Gap 00102013 PP#3F1414 00101923 PP#2F1188 00102179 00102180 00102114 00102130 00140001 PP#7F1953 00162562 00101977 00102061 00102123 PP#3F1414 00080815 00102012 00102014 00102172 00164424 00159572 42305801 42827801 43299004 PP#8F2107 00135031 00159573 40884601 00035368 00035369 00101966 00101923 PP#2F1188 42226201 42226201 Toxicology 870.1100 870.1200 870.1300 870.2400 870.2500 870.2600 870.3150 81-1 81-2 81-3 81-4 81-5 81-6 82- Ib Acute Oral Toxicity Rat Acute Dermal Toxicity Rabbit/Rat Acute Inhalation Toxicity Rat Primary Eye Irritation Rabbit Primary Skin Irritation Dermal Sensitization 13-Day Dietary Dog A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C 00057333 00091241 00069916 00069916 00057333 00069916 00069916 N/A 41919901 Page 73 of 191 ------- 870.3700a 870.3700b 870.3800 870.4100a 870.4 lOOb 870.4200 870.4300 870-5300 870.5385 870.5550 870.6200a 870.6200b 870.6300 870.7485 N/A N/A N/A Special Study 83-3a 83 -3b 83-4 83-1 83-1 83-2 83-5 84-2 84-2 N/A N/A N/A N/A Developmental Toxicity (Teratogenicity) Rat Developmental Toxicity (Teratogenicity) Rabbit 2-Generation Reproduction Rat Chronic Toxicity Rat Chronic Toxicity Dog Carcinogenicity Rat Chronic Toxicity /Carcinogenicity Mouse and Rat Gene Mutation Mammalian Cytogenetics: Bone Marrow Chromosome Aberration Unscheduled DNA Synthesis in Mammalian Cells Acute Neurotoxicity Screening Battery Subchronic Neurotoxicity Screening Battery Developmental Neurotoxicity Metabolism and Pharmacokinetics Rat Dominant Lethal Study Special Neurotoxicity Studies: Moser VC Acute Oral Study (Human) Inveresk Comparative Cholinesterase Assay A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C A,B,C 41004501 0132668 42148401 43045401 40695401 42191501 43045401 00044732 00044733 00044734 00148168 41661301 41663102 00141673 43442301 43829602 43829601 00102022 00102023 43575101 45068601 (1999) TAP 157 94-106 42373001 (1992) 46131001 (supplementary report) Data Gap Occupational/Residue Exposure N/A N/A N/A N/A Aldicarb Specific Study Terbufos Study A,B,C A,B,C 43852501 44793301 Page 74 of 191 ------- Appendix C. Technical Support Documents Additional documentation in support of this RED is maintained in the OPP docket EPA-HQ-OPP-2005- 0253. This docket may be accessed in the OPP docket room located at Room S-4900, One Potomac Yard, 2777 S. Crystal Drive, Arlington, VA. It is open Monday through Friday, excluding Federal holidays, from 8:30 a.m. to 4:00 p.m. All documents may be viewed in the OPP docket room or downloaded or viewed via the Internet at the following site: http://www.regulations.gov. The docket initially contained preliminary risk assessments, supporting documents, and technical (or manufacturing-use) registrant error comments for aldicarb as of November 14, 2006. After a sixty-day public comment period, EPA considered the public comments that were submitted to the docket and revised the risk assessments as necessary. The revised risk assessments, any supporting documents that needed to be revised, impact assessments, and memos describing the the Biological and Economic Assessment Division (BEAD), Environmental Fate and Effects Division (EFED), and Health Effects Division (HED) response to public comments will be added to the docket on September 26, 2006. The Agency documents in the docket include: 1. Federal Register Notice: Aldicarb Interim Reregi strati on Eligibility Decision; Notice of Availability. 2. Reader's Guide to the Aldicarb E-Docket # EPA-HQ-OPP-2005-0163. 3. Reregi strati on Eligibility Decision (RED) Document for Aldicarb. 4. BEAD Response to Comments Submitted to Docket EPA-HQ-OPP-2005-0163. 5. Quantitative Impact Analysis for At-peg Application of Aldicarb to Peanuts (DP 337549). 6. Significance of Aldicarb Use in the Production of Dry Beans, Soybeans, Pecans, Sweet Potatoes, Cotton and Citrus. 7. EFED Response to Public Comments for Aldicarb RED: Docket ID# Opp-2005- 0163-0176. 8. Aldicarb - Ecological risk results for alternative application rate and incorporation efficiencies. 9. Use of Aldicarb for Lygus Bug Suppression, Aphids, and Mites on Alfalfa Grown for Seed Production. 10. Use of Aldicarb for Leaf Minors on Coffee, forNematodes on Coffee and Sugarcane, and for Aphids and Flea Beatles on Tobacco. Page 75 of 191 ------- 11. Review of "A Retrospective Ground Water Monitoring Study for Aldicarb and Its Metabolites in the Southeastern United States (MRID 467937-06); Mississippi Delta (MRID 467937-05); Texas (MRID 467937-04); California (MRID 467937- 03); and Pacific Northwest (MRID 467937-02). 12. ADDENDUM to: Aldicarb - Ecological risk results for alternative application rate and incorporation efficiencies 13. Aldicarb (List A Case 0140, Chemical ID No. 098301). HED Response to Comments Received During the Public Comment Period. 14. HED Revised Human Health Risk Assessment for the Reregi strati on Eligibility Decision Document (RED). Page 76 of 191 ------- Appendix D. Citations Considered to be Part of the Database Supporting the Reregistration Decision (Bibliography) Guide to Appendix D 1. Contents of Bibliography. This bibliography contains citations of all studies considered relevant by EPA in arriving at the positions and conclusions stated elsewhere in the Reregistration Eligibility Document. Primary sources for studies in this bibliography have been the body of data submitted to EPA and its predecessor agencies in support of past regulatory decisions. Selections from other sources including the published literature, in those instances where they have been considered, are included. 2. Units of Entry. The unit of entry in this bibliography is called a "study." In the case of published materials, this corresponds closely to an article. In the case of unpublished materials submitted to the Agency, the Agency has sought to identify documents at a level parallel to the published article from within the typically larger volumes in which they were submitted. The resulting "studies" generally have a distinct title (or at least a single subject), can stand alone for purposes of review and can be described with a conventional bibliographic citation. The Agency has also attempted to unite basic documents and commentaries upon them, treating them as a single study. 3. Identification of Entry. The entries in this bibliography are sorted numerically by Master Record Identifier, or "MRID" number. This number is unique to the citation, and should be used whenever a specific reference is required. It is not related to the six-digit "Accession Number" which has been used to identify volumes of submitted studies (see paragraph 4(d)(4) below for further explanation). In a few cases, entries added to the bibliography late in the review may be preceded by a nine character temporary identifier. These entries are listed after all MRID entries. This temporary identifying number is also to be used whenever specific reference is needed. 4. Form of Entry. In addition to the Master Record Identifier (MRID), each entry consists of a citation containing standard elements followed, in the case of material submitted to EPA, by a description of the earliest known submission. Bibliographic conventions used reflect the standard of the American National Standards Institute (ANSI), expanded to provide for certain special needs. a. Author. Whenever the author could confidently be identified, the Agency has chosen to show a personal author. When no individual was identified, the Agency has shown an identifiable laboratory or testing facility as the author. When no author or laboratory could be identified, the Agency has shown the first submitter as the author. b. Document date. The date of the study is taken directly from the document. When the date is followed by a question mark, the bibliographer has deduced the date from the evidence contained in the Page 77 of 191 ------- document. When the date appears as (1999), the Agency was unable to determine or estimate the date of the document. c. Title. In some cases, it has been necessary for the Agency bibliographers to create or enhance a document title. Any such editorial insertions are contained between square brackets. d. Trailing parentheses. For studies submitted to the Agency in the past, the trailing parentheses include (in addition to any self-explanatory text) the following elements describing the earliest known submission: (1) Submission date. The date of the earliest known submission appears immediately following the word "received." (2) Administrative number. The next element immediately following the word "under" is the registration number, experimental use permit number, petition number, or other administrative number associated with the earliest known submission. (3) Submitter. The third element is the submitter. When authorship is defaulted to the submitter, this element is omitted. (4) Volume Identification (Accession Numbers). The final element in the trailing parentheses identifies the EPA accession number of the volume in which the original submission of the study appears. The six-digit accession number follows the symbol "CDL," which stands for "Company Data Library." This accession number is in turn followed by an alphabetic suffix which shows the relative position of the study within the volume. Page 78 of 191 ------- Bibliography 6300 Hiddleson, L.; Bishop, J.P. (1966) Report No. 074566-045. (Unpublished study received Mar 24, 1976 under 359-620; submitted by Rhone-Poulenc, Inc., Monmouth Junction, N.J.; CDL:095197-I) 6606 Butts, R.F.; Simpson, G.W. (1969) Zolone EC-Potatoes: Final Report No. BB 69-60. (Unpublished study received Dec 7, 1972 under 3F1337; prepared in cooperation with Univ. of Maine, Entomology Dept, submitted by Rhodia, Inc., New Brunswick, N.J.; CDL: 094849-AD) 6618 Wang, D.; Bacon, O.G. (1971) Zolone EC-Potatoes: Final Report No. FW 71-52. (Unpublished study received Dec 7, 1972 under 3F1337; prepared in cooperation with Univ. of California-Davis, Dept. of Entomology, submitted by Rhodia, Inc., New Brunswick, N.J.; CDL:094849-AR) 6848 Stafford, E. (1966) Report No. PA 66-46. (Unpublished study received Jul 5, 1968 under 8F0668; submitted by Chipman Chemical Co., Inc., Burlingame, Calif.; CDL:092027-BG) 6962 Pollet, O.K.; Aitken, J.B. (1977) Pest control for kernal pecans. Pecan South (Apr): 138-140. (Alsolnunpublished submission received Jun 9, 1977 under 359-620; submitted by Rhone- Poulenc, Inc., Monmouth Junction, N.J.; CDL:230375-T) 7727 Jenkins, L.E. (1974) Evaluation of Insecticides for Control of Insects on Dry Beans, 1974. (Unpublished study received Mar 31, 1975 under 201-347; prepared by Colorado State Univ., Bay Farm Experiment Station, Dept. of Zoology-Entomology, submitted by Shell Chemical Co., Washington, D.C.; CDL:223468-AK) 7741 Reynolds, H.T. (1971) Biological Effects of Lannate and Fundal/ Galecron Applied to Cotton for Residue Analysis. (Unpublished study received Jun 29, 1976 under 201-347; prepared by Univ. of California-Riverside, Citrus Research Center and Agricultural Experiment Station, Dept. of Entomology; submitted by Shell Chemical Co., Washington, D.C.; CDL:232404-P) 7750 Pfrimmer, T.R. (1974) Results of Insecticide Tests with Materials Furnished by the Shell Chemical Company. (Unpublished study received Jun 29, 1976 under 201-347; prepared by U.S. Agricultural Research Service, Delta States Agricultural Research Center, Bioenvironmental Insect Control Laboratory, submitted by Shell Chemical Co., Washington, D.C.; CDL:232404-AI) 7808 Reed, J.A. (1969) Potato Plots-1969. (Unpublished study received Feb 28, 1972 under 352- 342; prepared by Rutgers Univ., submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL: 003033-L) 7816 Watson, T.F.; Barnes, K.K.; Fullerton, D.G.; et al. (1970) Field and Laboratory Investigations on Cotton Insects in Arizona: 1970. (Summary report prepared for Cotton Insects Research and Control Conference, Atlanta, Georgia, Jan 12 and 13, 1971. Unpublished study received Apr 18, 1972 under 352-342; prepared by Univ. of Arizona, Agricultural Experiment Station, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:003040-I) 7828 Evans, A.W.; Pate, T. (1966) Thrips Infestations, Average Plant Heights, Average Stand Counts, Rates of Technical Materials in Ounces, Type of Treatments and Insecticides Used in Thrips Test at Clarksdale, Mississippi during 1966: Table 1. (Unpublished study received Oct 15, 1968 under 352-342; prepared in cooperation with Mississippi State Univ., submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:003003-D) Page 79 of 191 ------- 8096 Brodie, B.B. (1968) The Effects of Nematicidesic Treatments on Yield of Flue-Cured Tobacco, Tifton, Georgia 1968. (Unpublished study received Apr 22, 1969 under 352-342; prepared by U.S. Dept. of Agriculture, Georgia Coastal Plain Experiment Station, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:003007-F) 8129 Watson, T.F. (1972) Field and Laboratory Investigations on Cotton Insects in Arizona. (Summary report prepared for Cotton Insect Research and Control Conference, Phoenix, Arizona, Jan 9 and 10, 1973; unpublished study received May 24, 1976 under 352-342; submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:225098-K) 8256 Todd, J. (1970) Protection of Seedling Soybeans from Damage by Lesser Cornstalk Borer and/or Three-Cornered Alfalfa Hopper with Granular Insecticides. (Unpublished study received Jun 29, 1976 under 201-347; prepared by Georgia Experiment Station, submitted by Shell Chemical Co., Washington, D.C.; CDL:232405-AL) 8298 Bacon, O.G.; McCalley, N. (1966) Control of the Potato Tuberworm. (Unpublished study received Jan 21, 1970 under OF0886; prepared by Univ. of California-Davis, submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:091530-R) 8317 Reed, J.P. (1969) Potato Insect Control Test. (Unpublished study received Jan 21, 1970 under OF0886; prepared by Rutgers Univ., Dept. of Entomology and Zoology, submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:091530-AH) 8606 Radcliffe, E.B. (1973) 1973 Potato Insecticide Trials, Rosemount, Minnesota. (Unpublished study received Sep 21, 1977 under 352-342; prepared by Univ. of Minnesota, Dept. of Entomology, Fisheries, and Wildlife, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:231911-E) 8639 Bacon, O.G.; McCalley, N. (1966) Green Peach Aphid Populations Occurring on Potato Foliage in Plots Treated for Control of the Potato Tuberworm. (Unpublished study received Nov 16, 1971 under 352-342; prepared by Univ. of California-Davis, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL: 00303 l-O) 8924 Polles, S.G. (1973) Results of Efficacy Studies Using Lannate and Various Insecticides on Pecan Trees. (Unpublished study received Sep 21, 1976 under 352-342; submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:095289-H) 9073 Stier, E.F. (1969) Flavor Evaluation Report on Potatoes. (Unpublished study received Jan 21, 1970 under OF0886; prepared by Rutgers Univ., Dept. of Food Science, submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:091530-H) 9103 Thurston, R. (1968) Effect of Granular and Foliar Insecticides on Leaf Damage by Tobacco Hornworms: Table 4. (Unpublished study received Feb 12, 1970 under 352-342; prepared by Univ. of Kentucky, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:003013-E) 9247 Morishita, P. (1973) Thrips Control with Systemics. (Unpublished study received Aug 25, 1976 under 352-342; prepared by Univ. of California-Riverside, Citrus Research Center and Agricultural Experiment Station, Dept. of Entomology, submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:227322-M) 10163 Wells, J.C. (1970) Peanut Nematocide Test-1970. (Unpublished study including letter dated Oct 22, 1970 from J.C. Wells to Bill Wilner, received Oct 5, 1973 under 3G1359; prepared by North Carolina State Univ., Agricultural Extension Service, Dept. of Plant Pathology, submitted by PPG Industries, Inc., Chemical Div., Pittsburgh, Pa.; CDL:093629-I) Page 80 of 191 ------- 11390 Schulz, J.T.; Kamali, K.; Ehart, R. (1971) Biology, Ecology and Control of Sunflower Insects. (Unpublished study received Jun 4, 1974 under 100-501; prepared by North Dakota State Univ., Agricultural Experiment Station, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:094016-G) 11418 Pollet, O.K. (1975) Pecan Demonstration Orchard Treatments, 1975. (Unpublished study including letter dated Dec 17, 1976 from O.K. Pollet and J.B. Aitken to Steve Dumford, received Dec 22, 1977 under 100-501; prepared by Clemson Univ., Cooperative Extension Service, Dept. of Entomology, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:232600-G) 11419 Pollet, O.K. (1976) Control of pecan weevil shuckworm and aphid in South Carolina. Pecan South (Jun):408-411. (Alsolnunpublished submission received Dec 22, 1977 under 100-501; submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:232600-H) 11873 Mistric, W.J. (1966) Report of R. J. Reynolds Tobacco Co. Regarding Cigarette Smoke Tests Made on Samples of Cured Tobacco from Field Experiments in 1965: Table 2. (Unpublished study including letters dated Dec 3, 1965 from R. Wenger to Walter J. Mistric and Sep 20, 1965 from to Thomas D. Lowman, received Dec 28, 1971 under 100-501; prepared by North Carolina State Univ. in cooperation with R. J. Reynolds Tobacco Co., submitted by Ciba- Geigy Corp., Greensboro, N.C.; CDL:000539-L) 11893 Armbrust, E.J.; Cothran, W.R.; Wood, T.K.; et al. (1966) Early Spring Insecticide Applications for Alfalfa Weevil Control. (Unpublished study received Oct 22, 1972 under 100-501; prepared by Cornell Univ., Dept. of Entomology and Limnology, Div. of Forage and Cereal Insect Investigations, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:000536-G) 12428 Gerhardt, P.O. (1965) Insect Control Investigations on Potatoes: Project 418. (Unpublished study received Nov 10, 1972 under 3F1323; prepared by Univ. of Arizona, Dept. of Entomology, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-D) 12435 Wells, A.; Wagner, D. (1967) Insecticide Evaluation on Potatoes-1967. (Unpublished study received Nov 10, 1972 under 3F1323; submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-O) 12438 Radcliffe, E.B. (1965) 1965 Potato Data. (Unpublished study received Nov 10, 1972 under 3F1323; prepared by Univ. of Minnesota, Dept. of Entomology, Fisheries, and Wildlife, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-R) 12440 Radcliffe, E.B. (1968) Control of Insect Pests of Potato with Various Rates and Formulations of Several Insecticides: Table 1. (Unpublished study received Nov 10, 1972 under 3F1323; submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-T) 12444 Reed, J.P.; Stier, E.F. (1965) Potato Insect Control Tests-1965. (Unpublished study received Nov 10, 1972 under 3F1323; prepared by Rutgers Univ., Dept. of Entomology and Economic Zoology, submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-X) 12539 Bacon, O.G. (1965) Ecology, Biology and Control of Insects and Mites Affecting the Seed Production of Alflafasic, Clovers and Other Small Seeded Legumes in California: Project No. H1735. (Unpublished study received May 8, 1970 under OF0892; prepared by Univ. of California-Davis, Agricultural Experiment Station, Dept. of Entomology, submitted by Geigy Chemical Corp., Ardsley, N.Y.; CDL:091543-J) Page 81 of 191 ------- 12561 Lawatsch, D.J.; Buchholz, C. (1968) Alfalfa Weevil Test. (Unpublished study including letter dated Jun 26, 1968 from D. J. Lawatsch to A. A. Di Edwardo, received May 8, 1970 under OF0892; submitted by Geigy Chemical Corp., Ardsley, N.Y.; CDL:091543-AQ) 12933 Heald, C.M.; Thames, W.H. (1969) Effect of Nematicides on Yield of Cotton Infected withRotylenchulus reniformis. (Unpublished study including letters dated Nov 17, 1969 from C.M. Heald to Clyde W. McBeth and Dec 2, 1969 from J.M. McBride to R.B. Boren, received Oct 5, 1971 under 201-119; prepared by U.S. Agricultural Research Service, Crops Research Div., submitted by Shell Chemical Co., Washington, D.C.; CDL:000777-E) 12948 Jorgenson, E.G. (1968) Yield of Treated Sugarbeets. (Unpublished study including letters dated Dec 6, 1968 from E.G. Jorgenson to Stanley T. Ichikawa and Jan 20, 1969 from J.L. Reed to Supervisor, New York Agricultural Chemicals Div., Pesticide Development Dept, Agronomics Herbicides, Nematocides and Fungicides, received Oct 5, 1971 under 201-119; prepared by U.S. Agricultural Research Service, Crops Research Div., Crops Research Laboratory, submitted by Shell Chemical Co., Washington, D.C.; CDL:000777-X) 12950 Ruppel, R.F.; Fogg, R.; Gomulinski, M.S.; et al. (1968) Sugar Beet Nematode, Granules, 1968. (Unpublished study received Oct 5, 1971 under 201-119; submitted by Shell Chemical Co., Washington, D.C.; CDL:000777-Z) 12959 Thomas, W.O.; Green, H.B. (1967) Insecticidal Control of Insects Attacking Southern Peas: Project No. SZ-10. (Unpublished study including letter dated Feb 10, 1969 from R. Boren to Supervisor, New York, Agricultural Chemicals Div., Pesticide Development, Agronomic Insecticides, received Oct 5, 1971 under 201-119; prepared by Mississippi State Univ., Truck Crops Branch Experiment Station, submitted by Shell Chemical Co., Washington, D.C.; CDL: 000777-AI) 12960 Thomas, W.O.; Green, H.B. (1967) Control of Soil Insects Attacking Sweet Potatoes: Project No. SZ-11. (Unpublished study received Oct 5, 1971 under 201-119; prepared by Mississippi State Univ., Truck Crops Branch Experiment Station, submitted by Shell Chemical Co., Washington, D.C.; CDL:000777-AJ) 12978 Brodie, B.B. (1966) Evaluation of Potential Properitary sic Chemicals for Root-Knot Control of Tobacco~1966. (Unpublished study received Oct 5, 1971 under 201-119; prepared by U.S. Agricultural Research Service, Crops Research Div., Georgia Coastal Plain Experiment Station, Nematology Investigations, submitted by Shell Chemical Co., Washington, D.C.; CDL:000777-BC) 13020 Miller, P.M. (1963) Tobacco Cyst Nematode Control. (Unpublished study received on unknown date under 2139-76; prepared by Connecticut Agricultural Experiment Station, submitted by Nor-Am Agricultural Products, Inc., Woodstock, 111.; CDL:025254-G) 13076 Martin, W.J.; Birchfield, W. (1968) Meloidogyne incognitaGroup. (Unpublished study received Oct 6, 1969 under 464-379; submitted by Dow Chemical U.S.A., Midland, Mich.; CDL:003591-E) 13077 Martin, W.J.; Birchfield, W. (1968) Rotylenchulus reniformis: Efficacy of Nematocides on Sweet Potatoes: #8714. Unpublished study. 27 p. 13079 Martin, W.J.; Birchfield, W. (1968)Meloidogyne incognitaGroup and Streptomyces ipomoea. (Unpublished study received Oct 6, 1969 under 464-379; submitted by Dow Chemical U.S.A., Midland, Mich.; CDL:003591-H) Page 82 of 191 ------- 13090 Graham, T.W. (1968) 1968 Field Nematocide Tests for Control of Tobacco Nematodes. (Unpublished study including letter dated Sep 12, 1968 from T.W. Graham to Cooperators, received Oct 6, 1969 under 464-379; prepared by U.S. Agricultural Research Service, Tobacco Breeding and Disease Investigations, submitted by Dow Chemical U.S.A., Midland, Mich.; CDL:003590-T) 13794 Thompson, H.E. (1966) Elm Leaf Beetle Control in Kansas: 1961-1966. (Unpublished study including letter dated Feb 2, 1967 from H.E. Thompson to J.J. Mauget Co., received Nov 21, 1967 under 7946-1; prepared by Kansas State Univ., Dept. of Entomology, submitted by J.J. Mauget Co., Burbank, Calif.; CDL:008103-AC) 13797 Arnett, W.H. (1965) Elm Leaf Beetle Control with Systemic Chemicals: Report No. 18098. (Unpublished study received Nov 21, 1967 under 7946-1; prepared by Univ. of Nevada for Chemagro Corp., submitted by J.J. Mauget Co., Burbank, Calif; CDL: 008103-AM) 13962 Walton, R.R.; Burton, R.L. (1963) The Use of Systemic Insecticides for the Control of the Nantucket Pine Moth, Rhyacionia frustrana(Comst), on Pines in Oklahoma, 1962-63. (Unpublished study received Jun 26, 1967 under 201-229; prepared by Oklahoma State Univ., Dept. of Entomology, submitted by Shell Chemical Co., Washington, D.C.; CDL:000938-W) 13987 Brooks, R.F. (1968) Spiral Aphid: Test No.: RF 58. (Unpublished study including letter dated Nov 25, 1968 from R.F. Brooks to Jack T. Reinhardt, received Feb 3, 1977 under 201-274; prepared by Univ. of Florida, Institute of Food and Agricultural Sciences, Citrus Experiment Station, submitted by Shell Chemical Co., Washington, D.C.; CDL:095827-H) 14394 Stier, E.F. (1965) Flavor Evaluation Report on Potatoes. (Unpublished study received Nov 10, 1972 under 3F1323; submitted by Ciba-Geigy Corp., Greensboro, N.C.; CDL:093552-CF) 14455 Brodie, B.B.; Dukes, P.O. (1966) Field Performance of Selected Nematocides and Soil Fumigants: Line Project No.: CR f2-16. (Unpublished study received Oct 5, 1971 under 201- 119; prepared by U.S. Agricultural Research Service, Crops Research Div., Georgia Coastal Plain Experiment Station, Nematology Investigations, submitted by Shell Chemical Co., Washington, D.C.; CDL: 000777-BB) 14458 North Carolina State University, Research on Wheels (1965) Tobacco Summary Report of 1965 Data. Raleigh, N.C.: NCSU. (Plant pathology information note no. 133; alsolnunpublished submission received Nov 11, 1966 under 464-240; submitted by Dow Chemical U.S.A., Midland, Mich.; CDL:003480-A) 14927 Schaefer, R.; Koehler, C.; Kirby, M. (1975) Control of Greenhouse Whiteflies with Multiple Applications. (Unpublished study received Jul 12, 1977 under 239-EX-67; prepared in cooperation with Univ. of California-Berkeley, Dept. of Entomology, submitted by Chevron Chemical Co., Richmond, Calif.; CDL:233115-E) 14949 Sleesman, J.P. (1972) Vegetable Insect Control Experiments. Wooster: Ohio Agricultural Research and Development Center, Dept. of Entomology. (Ent. misc. publication 73-1; report no. 36258; pp. 1-6,11-17 only; also In unpublished submission received Jul 24, 1973 under 4F1424; submitted by Mobay Chemical Corp., Agricultural Div., Kansas City, Mo.; CDL:094861-I) 15140 Cooledge, C.Y.; Murphy, D. W.; Mau, R.F.L. (1978) Orthene Use on Various Plants. (Unpublished study received Dec 21, 1978 under 239-2427; prepared in cooperation with Univ. of Hawaii, Agricultural Experiment Station, submitted by Chevron Chemical Co., Richmond, Calif.; CDL:236631-M) Page 83 of 191 ------- 15141 Murphy, D.W.; Getting, R. (1977) Mealybug, Greenhouse Foliage Plants, Compressed Air Spray, One Application. (Unpublished study received Dec 21, 1978 under 239-2427; prepared in cooperation with Univ. of California-Riverside, Dept. of Entomology, submitted by Chevron Chemical Co., Richmond, Calif.; CDL: 236631-N) 15285 Goyer, R. (1972) Orthene 75 S: Artificial Diet. (Unpublished study received Jun 30, 1975 under 239-2443; prepared in cooperation with Cornell Univ., Dept. of Entomology, submitted by Chevron Chemical Co., Richmond, Calif.; CDL:222345-D) 15973 Bass, M.H.; Guthrie, C.D.; Cobb, P.P.; et al. (1972) Annual Report for Period Jan. 1 to Dec. 31, 1972: Biology and Control of Insect Pests of Soybeans and Peanuts: Ala-274, RRF Ala- 295, S-74. (Unpublished study received Jun 29, 1976 under 201-347; prepared by Auburn Univ., Zoology-Entomology Dept., submitted by Shell Chemical Co., Washington, D.C.; CDL:232408-N) 16013 Sorensen, K.A. (1973) Fruit and Vegetable Insects. (Unpublished study received Jun 29, 1976 under 201-347; prepared by North Carolina State Univ., submitted by Shell Chemical Co., Washington, D.C.; CDL:232410-V) 20129 Riverside Chemical Company (1967) Effect of Combinations of Herbicides and Systemic Insecticides on Cotton Planted April 24, 1967. (Unpublished study received Sep 26, 1968 under 9779-93; CDL:227188-P) 20600 Arnold, E.; Wells, A. (1967) Report No. C 67-42. (Unpublished study received Dec 8, 1967 under 8F0668; submitted by Chipman Chemical Co., Inc., Burlingame, Calif; CDL:092961- H) 22444 Waddill, V. (1977) Evaluation of insecticides for control of insect pests of tomatoes, 1977. Insecticide and Avaricide Tests 3: 109. (Alsolnunpublished submission received Mar 26, 1979 under 352-342; submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.; CDL:237888-I) 25162 Union Carbide Agricultural Products Company (1979) Magnitude of the Residue. (Unpublished study received Jan 23, 1980 under 264330; CDL:099219-A) 25163 Union Carbide Agricultural Products Company (1976) Nature of the Residue. (Unpublished study received Jan 23, 1980 under 264330; CDL:099219-B) 25164 Union Carbide Agricultural Products Company (1975) Safety to the Consumer. (Unpublished study received Jan 23, 1980 under 264330; CDL:099219-C) 25165 Union Carbide Agricultural Products Company (1978) Description of the Analytical Methods. Summary of studies 099219-E and 099219F. (Unpublished study received Jan 23, 1980 under 264-330; CDL:099219-D) 25166 Union Carbide Agricultural Products Company (1978) A Method for the Determination of Total Toxic Aldicarb Residues in Grapes. Method Aldicarb-FPD-General dated Aug 1978. (Unpublished study received Jan 23, 1980 under 264-330; CDL:099219-E) 25167 Union Carbide Agricultural Products Company (1977) A Confirmatory Procedure for the Identification of Aldicarb Residues by Gas Chromatography Utilizing a Non-polar Column. Method AldicarbFPD-Confirmatory dated Feb 1977. (Unpublished study received Jan 23, 1980 under 264-330; CDL:099219-F) Page 84 of 191 ------- 25168 Cox, J.A.; Jubb, G.L., Jr.; Taschenberg, E.F.; et al. (1978) Efficacy Data. (Unpublished study received Jan 23, 1980 under 264330; prepared in cooperation with Pennsylvania State Univ., Vineyard Experiment Station and others, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:099220-A) 25487 Allen, W.W.; Johnson, R.; Morishita, F.S.; et al. (1979) Efficacy and Phytotoxicity. (Unpublished study received Jan 23, 1980 under MN 80/1; prepared in cooperation with Univ. of California-Berkeley, Dept. of Entomology and others, submitted by state of Minnesota for Penick Corp., Lyndhurst, N.J.; CDL: 241667-A) 25511 Back, R.C. (1979) Temik Aldicarb Pesticide: The Long Island Water Situation. (Unpublished study received Jan 30, 1980 under 101669; submitted by Union Carbide Corp., Arlington, Va.; CDL: 241702-A) 28644 Union Carbide Agricultural Products Company (1980) Aldicarb Pesticide Mechanism of Action and Therapy: Part II. (Unpublished study received Jan 22, 1980 under 264-330; CDL:241639-A) 28645 Maronpot, R.R. (1980) Effect of a Single Peroral Dose of Aldicarb on Cholinesterase Inhibition and Recovery in the Rat: Project Report 43-2. (Unpublished study received Jan 22, 1980 under 264-330; prepared by Carnegie-Mellon Univ., Institute of Research, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:241639-B) 28646 Maronpot, R.R. (1980) Effect of a Single Peroral Dose of Aldicarb on Cholinesterase Inhibition and Recovery in the Rabbit: Project Report 43-3. (Unpublished study received Jan 22, 1980 under 264-330; prepared by Carnegie-Mellon Univ., Institute of Research, submitted by Union Carbide Agricultural Products Co., Ambler, Pa; CDL:241639-C) 28647 Maronpot, R.R. (1980) Effect of a Single Oral Dose of Aldicarb on Cholinesterase Inhibition and Recovery in the Dog: Project Report 43-4. (Unpublished study received Jan 22, 1980 under 264330; prepared by Carnegie-Mellon Univ., Institute of Research, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:241639-D) 28648 Panasevich, R.E.; Matthews, R. J. (1980) The Effects of Aldicarb #2 DEQ-85 upon Endogenous and Exogenous Acetylcholine When Administered at Threshold Doses: Study No. PH-234-OC-001-79. (Unpublished study received Jan 22, 1980 under 264-330; prepared by Pharmakon Laboratories, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:241639-E) 28811 Landis, B.J.; Jemmett, D.; Onsager,; et al. (1971) Efficacy Data for Control of Wireworms in Potatoes. (Unpublished study including test nos. SI-25-P-72, SI-26-P-72, SI-96-P-71..., received Nov 20, 1972 under 476-1995; prepared in cooperation with U.S. Agricultural Research Service, Entomology Research Div. and others, submitted by Stauffer Chemical Co., Richmond, Calif.; CDL:003842-K) 28813 Sullivan, P.; Wright, J.; Gold, L.; et al. (1972) Soil Insecticide Field Test Data: Test No. I- 336-JW-72. (Unpublished study including test nos. I-334-JW-72,1-333-JW-72,1-332-JW- 72..., received Nov 20, 1972 under 476-1995; prepared in cooperation with United States Sugar Corp. and others, submitted by Stauffer Chemical Co., Richmond, Calif.; CDL:003842- M) 29290 Union Carbide Corporation (1967) Performance Data Temik 10G~Cotton. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-A) Page 85 of 191 ------- 29291 Union Carbide Corporation (19) The Name, Chemical, Identity, and Composition of the Pesticide Chemical: Temik. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-B) 29292 Union Carbide Corporation (1968) Determination of Technical Temik 2-Methyl-2- (methylthio)propionaldehyde O-(methylcarbamoyl) oxime and Temik 10G Aldicarb Pesticide by Infrared Analysis. Method 64C-21V5-K46 dated Oct 25, 1968. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-C) 29293 Union Carbide Corporation (1968) Full Reports of Investigations Made with Respect to the Safety of the Pesticide Chemical: Temik. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-D) 29294 Union Carbide Corporation (1968) Metabolism and Toxicity of Metabolites. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-E) 29295 Union Carbide Corporation (1968) Toxicity of the Formulated Product Temik 10G Aldicarb Pesticide. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-F) 29296 Union Carbide Corporation (1968) Metabolism in Plants. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-G) 29297 Beckham, C.M.; Brooks, O.; Cowan, C.B.; et al. (1968) Introduction. (Unpublished study received Feb 6, 1969 under 1016-69; prepared in cooperation with Univ. of Georgia and others, submitted by Union Carbide Corp., Arlington, Va.; CDL:005587-H) 29298 Union Carbide Corporation (19) Cotton Foliage and Systemic Activity. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-I) 29299 Clarkson, V.A.; Fronek, F.; Bariola, L.A. (1968) Residue Data for Temik in Soil. (Unpublished study received Feb 6, 1969 under 1016-69; prepared in cooperation with Grower Services, Inc. and U.S. Dept. of Agriculture, submitted by Union Carbide Corp., Arlington, Va.; CDL:005587-J) 29300 Union Carbide Corporation (19) Description of Analytical Methods. (Unpublished study received Feb 6, 1969 under 1016-69; CDL: 005587-K) 29301 Union Carbide Corporation (19) Practical Methods for Removing Residues That Exceed Any Proposed Tolerance: Temik. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-L) 29302 Union Carbide Corporation (19) Reasonable Grounds in Support of the Petition: Temik. (Unpublished study received Feb 6, 1969 under 1016-69; CDL:005587-M) 29323 Bass, M.H.; Johnson, S.J.; Chiu, P. (1974) Biology and Control of Insect Pests of Soybeans and Peanuts: Report No. 43781. (Unpublished study including submitter summary, received Jul 1, 1975 under 3125-163; prepared by Auburn Univ., submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:115279-D) 29943 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1972) Aldicarb (A), Aldicarb Sulfoxide (ASO), Aldicarb Sulfone (ASO2) and a 1:1 Mixture of ASO:ASO2 Two Year Feeding in the Diet of Rats: Special Report 35-82. (Unpublished study received Jan 24, 1980 under 1016-69; prepared by Carnegie-Mellon Univ., submitted by Union Carbide Corp., Arlington, Va.; CDL:241658-A) Page 86 of 191 ------- 29986 Union Carbide Corporation (1975) Temik 15G Aldicarb Pesticide. (Unpublished study received Jun 30, 1978 under 1016-78; CDL: 097162-C) 29987 Union Carbide Corporation (1975) Temik Aldicarb Granular Pesticide. (Unpublished study received Jun 30, 1978 under 1016-78; CDL: 097162-D) 29988 Union Carbide Corporation (1972) Temik 10G Aldicarb Pesticide: Assay and Analysis for Impurities. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-E) 29989 Smith, F.F.; Maitlen, J.C.; McDonough, L.M.; et al. (1978) Report of Residue Analysis: PCY- 68-11. (Unpublished study received Jun 30, 1978 under 1016-78; prepared in cooperation with U.S. Agricultural Research Service, Entomology Research Div., Pesticide Chemicals Research Branch and others, submitted by Union Carbide Corp., Arlington, Va.; CDL:097162-G) 29990 Union Carbide Corporation (1977) Description of Analytical Methods. (Unpublished study received Jun 30, 1978 under 1016-78; CDL: 097162-H) 29991 Union Carbide Corporation (1977) Determination of Total Toxic Aldicarb Residues in Tomatoes by Gas Chromatography. Method dated Aug 1977. (Unpublished study received Jun 30, 1978 under 101678; CDL:097162-I) 29993 Union Carbide Corporation (1978) Practical Method for Removing Toxic Aldicarb Pesticide Residues from Tomatoes. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-J) 29994 Union Carbide Corporation (1977) Reasonable Grounds in Support of the Petition: Aldicarb. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-K) 29995 Lyons, R.; Lindquist,; Sorensen,; et al. (1977) Residues from Aldicarb on Tomatoes. (Unpublished study received Jun 30, 1978 under 1016-78; prepared by Michigan State Univ. and others, submitted by Union Carbide Corp., Arlington, Va.; CDL:097162-L) 29996 Union Carbide Corporation (1977) Confirmatory Procedure for the Identification of Aldicarb Residues Utilizing a Non-polar GLC Column. Method dated Feb 1977. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-M) 30423 Field, W.E.; Mellott, M.J. (1979) Oral LDI50A in Rabbits: Study No. CDC-UC-007-79. (Unpublished study received Feb 28, 1980 under 264-330; prepared by CDC Research, Inc., submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:242164-A) 30424 Field, W.E.; Mellott, M.J. (1979) Acute Dermal Toxicity in Rats: Study No. CDC-UC-008- 79. (Unpublished study received Feb 28, 1980 under 264-330; prepared by CDC Research, Inc., submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL: 242164-B) 30425 Field, W.E.; Mellott, M.J. (1979) Acute Dermal Toxicity in Rabbits: Study No. CDC-UC- 009-79. (Unpublished study received Feb 28, 1980 under 264-330; prepared by CDC Research, Inc., submitted by Union Carbide Agricultural Products Co., Ambler, Pa; CDL: 242164-C) 31311 Nigh, E.L., Jr.; Thomason, I.J.; Caveness, F.E.; et al. (1968) Quick Summary Reference of Performance of Temik 10G on Insects, Mites, Nematodes Attacking Cotton (Includes Data 1964 thru 1967). (Unpublished study received Jan 24, 1969 under 9F0798; prepared in cooperation with Univ. of Arizona, Dept. of Plant Pathology and others, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:091942-A) Page 87 of 191 ------- 31547 Allen, W.W.; Johnson, R.; Morishita, F.S.; et al. (1979) Efficacy and Phytotoxicity. (Unpublished study received Jan 11, 1980 under IL 80/1; prepared in cooperation with Univ. of California, Div. of Entomology, submitted by Illinois, Dept. of Agriculture, Plant & Apiary Protection for Penick Corp., Lyndhurst, N.J.; CDL:241606-A) 31565 Wilson, W.L.; Todd, F.A.; Leake, P.H. (1976) Sensory Evaluation of Cigarettes Made from Tobacco Treated with Standak 75% Wettable Powder Sulfocarb Pesticide (1974-1976). (Unpublished study received Feb 28, 1978 under 1016-79; prepared in cooperation with Imperial Tobacco, Ltd. and others, submitted by Union Carbide Corp., Arlington, Va.; CDL:232983-B) 31763 Blackmon, C.W.; Farrar, L.L.; Smith, F.H.; et al. (1973) Addition to Synopsis of Biological Performance and Phytotoxicity on Cotton and Soybeans. (Unpublished study received Jan 3, 1974 under 3125-213; prepared in cooperation with Clemson Univ.; Edisto Experiment Station and others, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:094066-A) 32245 Union Carbide Corporation (1975) Temik 10G Aldicarb Pesticide. (Unpublished study received Jun 30, 1978 under 1016-78; CDL: 097162-B) 32246 Sleesman, J.P.; Hofmaster, R.N.; Waterfield, R.L.; et al. (1978) Discussion of Performance of Temik: Aldicarb Pesticide. (Unpublished study received Jun 30, 1978 under 1016-78; prepared in cooperation with Ohio State Univ., Agricultural Experiment Station and others, submitted by Union Carbide Corp., Arlington, Va.; CDL:097163-A) 32505 Allen, W.W.; Morishita, F.S.; Koranski, D.S.; et al. (1979) Efficacy and Phytotoxicity. (Unpublished study received Apr 24, 1980 under DE 80/5; prepared in cooperation with Univ. of California-Berkeley, Div. of Entomology and others, submitted by Delaware, Dept. of Agriculture, Div. of Production and Promotion for Penick Corp., Lyndhurst, N.J.; CDL:242353-A) 35363 Union Carbide Corporation (1971) Ingestion of Aldicarb by Human Volunteers: A Controlled Study of the Effects of Aldicarb on Man. Includes undated methods entitled: Blood cholinesterase determination by a radiometric method; Aldicarb: The determination of residues in human urine. (Unpublished study including letter dated Feb 5, 1971 from C.U. Dernehl to R.C. Back, received Jul 26, 1971 under 1F1008; CDL:091747-A) 35364 Union Carbide Corporation (1970) Response to Comments on Pesticide Petition OF1008: Aldicarb. (Unpublished study received Jul 26, 1971 under 1F1008; CDL:091747-B) 35365 Bull, D.L.; Stokes, R.A.; Coppedge, J.R.; et al. (1970) Further studies of the fate of Aldicarb in soil. Journal of Economic Entomology 63(4): 1283-1289. (Alsolnunpublished submission received Jul 26, 1971 under 1F1008; submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-C) 35366 Coppedge, J.R.; Ridgway, R.L.; Bull, D.L. (1968) A Preliminary Report on the Movement and Persistence of Aldicarb in Soil. (U.S. Agricultural Research Service, Entomology Research Div., unpublished study; CDL:091747-D) 35367 Thomason, I.J. (1970) Efficacy Study Using Sugar Beets. (Unpublished study including letter dated Dec 29, 1970 from I.J. Thomason to Robert G. Haines, received Jul 26, 1971 under 1F1008; prepared in cooperation with Univ. of California-Riverside, Citrus Research Center and Agricultural Experiment Station, Dept. of Nematology, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-E) Page 88 of 191 ------- 35368 Lange, W.H.; Phillips, I.L. (1971) Residue Study Using Sugar Beets. (Unpublished study including letter dated Dec 9, 1970 from W.H. Lange to Robert Haines, received Jul 26, 1971 under 1F1008; prepared in cooperation with Univ. of California-Davis, Agricultural Experiment Station, Dept. of Entomology, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-F) 35369 Yun, Y.M.; Ellis, K.C. (1970) Residue Study Using Sugar Beets. (Unpublished study received Jul 26, 1971 under 1F1008; prepared in cooperation with Great Western Sugar Co., submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-H) 35370 Union Carbide Corporation (1970) Full Reports of Investigations Made with Respect to the Safety of the Pesticide Chemical: Temik. (Unpublished study received Jul 26, 1971 under 1F1008; CDL:091747-J) 35371 Weil, C.S.; Condra, N.I.; White, C. (1969) Temik Sulfoxide and Temik Sulfone Single Rabbit Skin Penetration Studies: Special Report 32-78. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-K) 35372 Carpenter, C.P.; Adams, J.T. (1969) Miscellaneous Toxicity Studies: Special Report 32-84. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL: 091747-L) 35373 Weil, C.S.; Woodside, M.D.; Bernard, J.R. (1970) Temik: Result of Feeding in the Diets of Rats for 7 Days: Special Report 33-5. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-M) 35374 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1970) 1:1 Temik: Temik Sulfone-Results of Feeding in the Diets of Mice for 7 Days: Special Report 33-6. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-N) 35375 Weil, C.S.; McGee, M.A.; Baughman, J.A. (1970) Temik and Other Materials-Miscellaneous Single Dose Peroral and Parenteral LDI50A Assays and Some Joint Action Studies: Special Report 33-7. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie- Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-O) 35376 Weil, C.S. (1970) Miscellaneous Toxicity Studies: Special Report 33-18. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-P) 35377 Woodside, M.D.; Chin, B.H.; Tallant, M.J. (1969) Temik 10GV 2Methyl-2- (methylthio)propionaldehyde O-(methyl carbamoyl)oxime: Peroral Dosing of a Hereford Heifer with Notes on Cholinesterase Inhibition: Special Report 32-82. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-Q) 35378 Weil, C.S.; McGee, M.A.; Baughman, J.L. (1970) Comparative Skin Penetration Toxicity of Temik 10GV and 15 Other Pesticide Formulations as Marketed: Special Report 33-15. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-R) Page 89 of 191 ------- 35379 Weil, C.S.; Woodside, M.D.; Bernard, J.R. (1969) 2-Methyl-2(methylsulfinyl)propanol-l: Results of Feeding in the Diets of Rats for One Week: Special Report 32-73. (Unpublished study received Jul 26, 1971 under 1F1008; prepared by Mellon Institute, submitted by Union Carbide Corp., Washington, D.C.; CDL: 091747-S) 35380 Schlinke, J.C. (1969) Toxicologic effects of five soil nematocides in cattle and sheep. Journal of the American Veterinary Medical Association 155(8):1364-1366. (Alsolnunpublished submission received Jul 26, 1971 under 1F1008; submitted by Union Carbide Corp., Washington, D.C.; CDL:091747-T) 36307 Union Carbide Corporation (1975) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-B) 36308 Union Carbide Corporation (1975) Temik 15G Aldicarb Pesticide: UCC No. l-21V5-1.8a. Includes methods UCC no. lB-21V5-l.ld dated Apr 21, 1975. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-C) 36309 Union Carbide Corporation (1972) Temik 10G Aldicarb Pesticide Assay and Analysis for Impurities. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-D) 36310 Union Carbide Corporation (1972) Nature of the Residues. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-E) 36311 McDonough, L.M.; Maitlen, J.C. (1967) Report of Residue Analysis: Report No. PCY-67-5. (U.S. Agricultural Research Service, Entomology Research Div., Pesticide Chemicals Research Branch, unpublished study; CDL:096440-F) 36312 Iley, J.R.; Baines,; Gunther,; et al. (19) Magnitude of the Residue. (Unpublished study received Oct 10, 1975 under 6G1689; prepared in cooperation with Applied Ag. Research, Inc. and others, submitted by Union Carbide Corp., Washington, D.C.; CDL:096440-G) 36313 Gunther, F.A.; Carman, G.E.; Baines, R.C.; et al. (1975) Aldicarb (TemikA(R)I) Residues in Oranges, Orange Leaves, and Soil after Soil Application in an Orange Grove. (Unpublished study received Oct 10, 1975 under 6G1689; prepared in cooperation with Univ. of California- -Riverside, Citrus Research Center and Agricultural Experiment Station, Dept. of Entomology and others, submitted by Union Carbide Corp., Washington, D.C.; CDL: 096440-H) 36314 Union Carbide Corporation (1975) Description of Analytical Methods: Aldicarb. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-I) 36315 Union Carbide Corporation (1975) Determination of Total Toxic Aldicarb Residues in Citrus Fruit. Method Aldicarb-FPD-General dated Jul 1975. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-J) 36316 Union Carbide Corporation (1975) Reasonable Grounds in Support of the Petition: Aldicarb. (Unpublished study received Oct 10, 1975 under 6G1689; CDL:096440-K) 41448 Union Carbide Corporation (1973) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-A) 41449 Union Carbide Corporation (1976) Nature and Magnitude of the Residue: Aldicarb. (Unpublished study received Jun 30, 1978 under 1016-78; CDL:097162-F) Page 90 of 191 ------- 42482 Godek, E.G.; Matthews, R.J.; Naismith, R.W.; et al. (1980) Ames Salmonella/Microsome Plate Test: (Aldicarb): PH 301-UC-004-80. (Unpublished study received Sep 2, 1980 under 264-330; prepared by Pharmakon Laboratories, submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:243142-A) 44731 Union Carbide Corporation (1976) Chronic Toxicity Studies (Carinogenic and Oncogenic Effects). Summary of studies 096503-B through 096503-D and096503-G. (Unpublished study received May 19, 1976 under 6E1792; CDL:096503-A) 44732 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1972) Aldicarb: 18 Month Feeding in Diet of Mice: Special Report 35-70. (Unpublished study received May 19, 1976 under 6E1792, prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL:096503-B) 44733 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1974) Aldicarb: 18-Month Feeding in the Diet of Mice, Study II: Special Report 37-98. (Unpublished study received May 19, 1976 under 6E1792; prepared by Carnegie-Mellon Univ., Carnegie-Mellon Institute of Research, submitted by Union Carbide Corp., Arlington, Va.; CDL: 096503-C) 44734 Weil, C.S. (1976) Reanalysis of Tumor Incidence Data of Aldicarb 18-Month Mouse Feeding Studies: Special Report 39-55. (Unpublished study received May 19, 1976 under 6E1792; prepared by Carnegie-Mellon Univ., Carnegie-Mellon Institute of Research, submitted by Union Carbide Corp., Arlington, Va.; CDL:096503-D) 44735 Union Carbide Corporation (1975) Studies Using Aldicarb. Summary of studies 096503-F. Summary of studies 096503-F through 096503-1. (Unpublished study received May 19, 1976 under 6E1792; CDL:096503-E) 44736 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1974) Aldicarb: Inclusion in the Diet of Rats for Three Generations and a Dominant Lethal Mutagenesis Test: Special Report 37-90. (Unpublished study received May 19, 1976 under 6E1792; prepared by Carnegie-Mellon Univ., Carnegie-Mellon Institute of Research, submitted by Union Carbide Corp., Arlington, Va.; CDL:096503-F) 44737 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1974) Aldicarb: Inclusion in the Diets of Dogs for Three Months: Special Report 37-12. (Unpublished study received May 19, 1976 under 6E1792; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, submitted by Union Carbide Corp., Arlington, Va.; CDL:096503-G) 44739 Moorefield, H.H.; Myers, R.C.; Weil, C.S. (1975) Temik 10G BC (Coal); 10G and 15G (Gypsum); 15G (Corn Cob): Comparative Toxicity Studies via Peroral, Dermal, and Inhalation Routes: Special Report 38-141. (Unpublished study received May 19, 1976 under 6E1792; prepared by Carnegie-Mellon Univ., Carnegie-Mellon Institute of Research, submitted by Union Carbide Corp., Arlington, Va.; CDL:096503-I) 44740 Union Carbide Corporation (1976) Reasonable Grounds in Support of the Petition: Temik. (Unpublished study received May 19, 1976 under 6E1792; CDL:096503-J) 51212 Bussian, R.A. (1980) Letter sent to H.H. Moorefield dated Oct 3, 1980: Temik TSX sample analysis. (Unpublished study received Oct 23, 1980 under 264-319; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:243546-E) 51314 Back, R.C. (1980) Letter sent to Charles T. Mitchell dated Mar 5, 1980 Temik 10% granular Aldicarb pesticide: Report on Welton Parker death. (Unpublished study received Mar 14, 1980 under 264-322; submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:243366-A) Page 91 of 191 ------- 51315 Back, R.C. (1980) Letter sent to Charles T. Mitchell dated Mar 5, 1980: Report on Paul Keller Case. (Unpublished study received Mar 14, 1980 under 264-330; submitted by Union Carbide Agricultural Products Co., Ambler, Pa.; CDL:243367-A) 53127 Union Carbide Corporation (1980) Aldicarb Residue Analytical Data: Suffolk County EUP. (Reports by various sources; unpublished study received Oct 3, 1980 under 264-EX-58; CDL:243417-A) 53341 Kinkead, E.R.; Chin, B.H.; Weil, C.S.; et al. (1968) Toxicity Studies on Temik (2-Methyl-2- methylthiopropionaldehyde-N-methylcarbamoyloxime) and Related Carbamates: Special Report 31-48. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-D) 53342 Striegal, J.A.; Condra, N.I.; Haun, C.C. (1963) Special Report: Comparison of the Acute Toxicity of Compound 21149 with Several of Its Analogues: Report 26-29. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-E) 53343 Weil, C.S.; McGee, M.A.; Baughman, J.A. (1970) Temik and Other Materials: Miscellaneous Single Dose Peroral and Parenteral LDI50 Assays and Some Joint Action Studies: Special Report 33-7. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-F) 53345 Johnson, H.E.; Sullivan, L.J.; McGee, M.A. (1968) Studies on an Effective Therapy for Overdoses of Temik, Temik sulfoxide, and Temik sulfone in the Rat: Special Report 31-139. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-H) 53346 Chin, B.H.; Sullivan, L.J. (1968) Toxicity of Carbamate to Rats. Pages l-14,InPesticide Subdivision Agriculture & Food Chemistry Division, 156th ACS National Meeting; Sep 9-13, 1968, Atlantic City, New Jersey. N.P. (Paper #121; Alsolnunpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-I) 53348 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1970) Temik (T), Temik Sulfoxide (TSO), Temik Sulfone (TSOI2), 1:1 TSO:TSOI2: Results of Feeding in the Diet of Rats for 7 Days: Special Report 33-81. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-K) 53350 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1972) Aldicarb (A), Aldicarb Sulfoxide (ASO), Aldicarb Sulfone (ASOI2) and a 1:1 Mixture of ASO:ASOI2: Two Year Feeding in the Diet of Rats: Special Report 35-82. (Unpublished study received Jan 18, 1977 under 1016- EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228976-M) 53353 Clarkson, V.A.; Hensley, W.H. (1968) Temik Insecticide: Toxicity of Temik, Temik sulfoxide and Temik sulfone to Bluegill Sunfish: Project No. 111B32. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228975-C) 53355 Union Carbide Corporation (1976) Metabolism and Toxicity of Metabolites. Summary of studies 228975-J through 228975-N and 228976-D. (Unpublished study received Jan 18, 1977 under 1016EX-37; CDL:228975-H) Page 92 of 191 ------- 53356 Kinkead, E.R.; Chin, B.H.; Weil, C.S.; et al. (1968) Toxicity Studies on the Probable Non- Carbamate Plant Metabolites of Temik (2-Methyl-2-methylthiopropionaldehyde-N- methylcarbamoyloxime): Special Report 31-30. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228975-J) 53358 Bartley, W.J.; Andrawes, N.R.; Chancey, E.L.; et al. (1970) Metabolism of Temik Aldicarb pesticide (2-Methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime) in the cotton plant. Journal of Agriculture and Food Chemicals 18(3):446-453. (Also In unpublished submission received Jan 18, 1977 under 1016-EX37; submitted by Union Carbide Corp., Arlington, Va.; CDL: 228975-L) 53362 Union Carbide Corporation (1972) Nature of the Residue: Metabolism in Animals. Summary of studies 229879-K through 228979-O. (Unpublished study received Jan 18, 1977 under 1016-EX-37; CDL: 228979-B) 53363 Union Carbide Corporation (1976) Nature of the Residue: Environmental Fate of Sulfocarb. Summary of studies 228979-J and 228979-P through 228979-AA. (Unpublished study received Jan 18, 1977 under 1016-EX-37; CDL:228979-C) 53364 Bull, D.L. (1968) Metabolism of UC-21149 (2-Methyl-2-(methythio)propionaldehyde o - (methylcarbamoyl)oxime) in cotton plants and soil in the field. Journal of Economic Entomology 61(6):15981602. (Also In unpublished submission received Jan 18, 1977 under 1016-Ex-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-D) 53366 Coppedge, J.R.; Lindquist, D.A.; Bull, D.L.; et al. (1967) Fate of 2-Methyl-2- (methylthio)propionaldehyde o (Methylcarbamoyl) oxirne (Temik) in cotton plants and soil. Journal of Agricultural andFood Chemistry 15(5):902-910. (Also in unpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-F) 53368 Metcalf, R.L.; Fukuto, T.R., Collins, C.; et al. (1966) Metabolism of 2-Methyl-2- (methylthio)-propionaldehyde o -(Methylcarbamoyl)oxime in plant and insect. Journal of Agricultural and Food Chemistry 14(6):579-584. (Also in unpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-H) 53369 Ridgway, R.L.; Jones, S.L.; Coppedge, J.R.; et al. (1968) Systemic activity of 2-Methyl-2- (methylthio)propionaldehydeo(methylcarbamoyl)oxime (UC-21149) in the cotton plant with special reference to the boll weevil. Journal of Economic Entomology 61 (6): 1705-1712. (Alsolnunpublished submission received Jan 18, 1977 under 1015-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-I) 53370 Hirsh, D.H.; Sheets, K.P.; Holsing, G.C. (1976) Sulfocarb: Fate in Aerobic and Anaerobic Soils. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-J) 53371 Borough, H.W.; Me, G.W. (1968) Temik-S metabolism in a lactating cow. Journal of Agricultural and Food Chemistry 16(3):460-464. (Also in unpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-K) Page 93 of 191 ------- 53372 Dorough, H.W.; Davis, R.B.; Me, G.W. (1970) Fate of Temik-Carbonl4 in lactating cows during a 14-day feeding period. Journal of Agricultural and Food Chemistry 18(1): 135-142. (Also in unpublished submission received Jan 18, 1977 under 1016-EX-37: submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-L) 53373 Hicks, B.W.; Dorough, H.W.; Mehendale, H.M. (1972) Metabolism of Aldicarb pesticide in laying hens. Journal of Agricultural and Food Chemistry 20(1): 151-156. (Alsolnunpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-M) 53374 Sullivan, L.J.; Tallant, M.J.; Kozbelt, S.J.; et al. (1968) The Excretion of CA14I Equivalents of 2-Methyl-2-(methylsulfonyl)propionaldehyde O-(Methylcarbamoyl)oxime by the Rat after a Single Peroral Dose: Special Report 31-130. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-N) 53375 Sullivan, L.J.; Eldridge, J.M.; Tallant, M.J.; et al. (1968) Urinary Metabolic Profiles as Determined by Silica Gel Chromatography of Urines from Rats and Dogs Dosed with Temik sulfone: Special Report 3 l-138a. (Unpublished study received Jan 18, 1977 under 1016-EX- 37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-O) 53377 Andrawes, N.R.; Holsing, G.C. (1976) Hydrolysis of UC-21865 Sulfocarb Pesticide in Aqueous Buffer Solutions: Project No. 111A14. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-Q) 53378 Borash, A.J.; Kramer, J.A., Jr.; Moorefield, H.H. (1973) Experiments Designed To Trace Movements of Aldicarb in Soil: Project No. 11 IB 13. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-R) 53379 Bromilow, R.H. (1973) Breakdown and fate of Oximecarbamate nematicides in crops and soils. Annals of Applied Biology 75(3):473479. (Alsolnunpublished submission received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-S) 53380 Richey, F.A., Jr.; Bartley, W.J. (1972) Temik Aldicarb Pesticide: Water Leaching of Aldicarb, Aldicarb Sulfoxide, Aldicarb Sulfone and Internal Standard Chloride Ion in Columns of Four Soil Types: Project No. 111A12. (Unpublished study received Jan 18, 1977 under 1016-EX- 37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-U) 53381 Richey, F.A., Jr.; Moorefield, H.H. (1972) Temik-Aldicarb Pesticide: Upward Movement of Aldicarb through soil during Water Evaporation: Project No. 111A12. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-V) 53382 Romine, R.R.; Meeker, R.L. (1972) Temik Aldicarb Pesticide: Leaching of Aldicarb into Sandy Soil with Irrigation of a Temik Treated Sugar Beet Field: Project No. 111A13. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-W) 53383 Romine, R.R.; Meeker, R.L. (1973) Accumulation of Aldicarb Residues in Fish Tissue from Chronic Exposure to Aldicarb, Aldicarb sulfoxide and Aldicarb sulfone in Aquaria Water: Project No. 111A13. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-X) Page 94 of 191 ------- 53384 Copeland, G.L.; Fink, R. (1973) Final Report: Acute and Chronic Exposure of Bluegill Sunfishto Aldicarb Carbamate Residues: Project No. 400-612. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Environmental Sciences Corp., submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-Y) 53385 Romine, R.R.; Halstead, C.B.; Gibson, C.E.; et al. (1968) Temik Insecticide: Leaching Characteristics of Temik lOGin Soils: Project No. 111A13. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228979-Z) 53386 Spurr, H.W., Jr.; Sousa, A. A. (1974) Potential interactions of Aldicarb and its metabolites on nontarget organisms in the environment. Journal of Environmental Quality 3(2): 130-133. (Also Inunpublished submission received jan 18, 1977 under 1016-EX37; submitted by Union Carbide Corp., Arlington, Va.; CDL: 228979-AA) 54410 Weil, C.S. (1977) Miscellaneous Toxicity Studies: Temik: Special Report 33-18. (Unpublished study received Aug 4, 1977 under 1016-79; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:231509-S) 54413 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1970) 1:1 Temik: Temik Sulfone: Results of Feeding in the Diets of Mice for 7 Days: Special Report 33-6. (Unpublished study received Aug 4, 1977 under 1016-79; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:231509-V) 54442 Weil, C.S.; Condra, N.I.; Geary, D.L.; Jr.; et al. (1974) Temik Aldicarb Pesticide 10G and 15G: Range Finding Toxicity Studies: Special Report 37-39. (Unpublished study received Aug 31, 1977 under 1016-69; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:231462-A) 55533 Myers, R.C.; Carpenter, C.P.; Calisti, L.J.; et al. (1977) Temik/ Terrazole/Terraclor Mixture (2:1:4) Range Finding Toxicity Studies: Project Report 40-126. (Unpublished study received Oct23, 1980 under 264-319; prepared by Carnegie-Mellon Univ., Institute of Research, Chemical Hygiene Fellowship, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL: 243546-D) 55534 Wolfe, G.W; Bristol, K.L. (1980) Final Report: Primary Eye Irritation Study in Rabbits: Project No. 400-634. (Unpublished study received Oct 23, 1980 under 264-319; prepared by Hazleton Laboratories America, Inc., submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:243546-F) Page 95 of 191 ------- 55535 Wolfe, G.W.; Wentz, K.L. (1980) Final Report: Primary Dermal Irritation Study in Rabbits: Project No. 400-633. (Unpublished study received Oct 23, 1980 under 264-319; prepared by Hazleton Laboratories America, Inc., submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:243546-G) 55536 Wolfe, G.W.; Bristol, K.L. (1980) Final Report: Acute Oral Toxicity Study in Rats: Project No. 400-631. (Unpublished study received Oct 23, 1980 under 264-319; prepared by Hazleton Laboratories America, Inc., submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:243546-H) 55537 Dauvin, E.M.; Wolfe, G.W.; Voelker, R.W.; et al. (1980) Final Report: Acute Dermal Toxicity Study in Rabbits: Project No. 400632. (Unpublished study received Oct 23, 1980 under 264-319; prepared by Hazleton Laboratories America, Inc., submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL: 243546-1) 57332 Kinkead, E.R.; Chin, B.H.; Weil, C.S.; et al. (1968) Toxicity Studies on Temik (2-Methyl-2- methylthiopropionaldehyde-M-methylcarbamoyloxime) and Related Carbamates: Special Report 31-48. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-D) 57333 Striegel, J.A.; Condra, N.I.; Haun, C.C. (1963) Special Report: Comparison of the Acute Toxicity of Compound 21149 with Several of Its Analogues: Report 26-29. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-E) 57335 Johnson, H.E.; Sullivan, L.J.; McGee, M.A. (1968) Studies on an Effective Therapy for Overdoses of Temik, Temik sulfoxide, and Temik sulfone in the Rat: Special Report 31-139. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL: 228152-H) 57336 Chin, B.H.; Sullivan, L.J. (1968) Toxicity of Temik on the Rat, Dog and Rabbit. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-I) 57337 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1968) Temik sulfone: Results of Feeding in the Diet of Rats for Six Months and Dogs for Three Months: Special Report 31-142. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL: 228152-J) 57338 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1970) Temik (T), Temik sulfoxide (TSO), Temik sulfone (TSOI2), 1:1 TSO:TSOI2: Results of Feeding in the Diet of Rats for 7 Days: Special Report 33-81. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-K) 57339 Weil, C.S.; Woodside, M.D.; Bernard, J.R. (1974) UC 21865: Results of Feeding in the Diet of Mice for 7 Days: Special Report 37-89. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Institute of Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-L) Page 96 of 191 ------- 57340 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1972) Aldicarb (A), Aldicarb sulfoxide (ASO), Aldicarb sulfone (ASOI2) and a 1:1 Mixture of ASO:ASOI2: Two Year Feeding in the Diet of Rats: Special Report 35-82. (Unpublished study received Jan 18, 1977 under 1016- EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-M) 57341 Weil, C.S.; Woodside, M.D.; Peterson, L.G.; et al. (1975) Aldicarb sulfoxide and Aldicarb sulfone Cholinesterase Inhibition Results after Periods of One to Fifty-Six Days of Inclusion in the Diets of Rats: Special Report 38-115. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Institute of Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:228152-N) 58625 Carpenter, C.P.; West, J.S.; McGee, M.A.; et al. (1966) Single Dose Toxicity Studies on Tranid: Report 29-41. (Unpublished study received Jun 13, 1966 under 1016-EX-19; prepared by Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL: 126464-A) 58631 Weil, C.S.; Bernard, J.; Woodside, M.D.; et al. (1966) Insecticide Temik: Teratogenic Potential in Rats: Report 29-81. (Unpublished study received Oct 8, 1966 under 1016-EX-24; prepared by Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL:126491-A) 58632 Carpenter, C.P.; Condra, N.I.; Humes, C.; et al. (1966) Temik 10G (10.5% Granular Formulation of Compound 21149) 15-Day Dermal Applications to Rabbits: Report 29-80. (Unpublished study received Oct 8, 1966 under 1016-EX-24; prepared by Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL: 126491-B) 58633 Stansbury, H.A., Jr. (1967) Letter sent to Frank J. McFarland dated Jul 10, 1967 Information on feeding of Temik-treated potatoes to livestock. Summary of study 126491-D. (Unpublished study received Jul 13, 1967 under 1016-EX-24; submitted by Union Carbide Corp., Arlington, Va.; CDL:126491-C) 58634 Dorough, H.W.; Me, G.W. (1967) Metabolism and Elimination of Temik-SA35I by a Lactating Cow. (Unpublished study received Jul 13, 1967 under 1016-EX-24; prepared by Texas A & M Univ., Dept. of Entomology, submitted by Union Carbide Corp., Arlington, Va.; CDL: 126491-D) 58635 Stansbury, H.A., Jr. (1967) Letter sent to Frank J. McFarland dated Jun 28, 1967 Decomposition of Temik in potatoes. (Unpublished study received Jul 3, 1967 under 1016- EX-24; submitted by Union Carbide Corp., Arlington, Va.; CDL:126491-E) 58636 Union Carbide Corporation (19) Formula for Temik 10G Granular Pesticide. (Unpublished study received on unknown date under 1016-EX-24; CDL:126491-F) 59356 Moorefield, H.H. (1979) Annotated Bibliography of N-Nitrosoaldicarb (Chronological Sequence). Summary of studies 241324-B through 241324-H. (Unpublished study received Nov 14, 1979 under 101669; submitted by Union Carbide Corp., Arlington, Va.; CDL: 241324-A) 59357 Hirsh, D.H.; Sheets, K.P.; Holsing, G.C. (1978) Temik aldicarb Pesticide Stability of N- Nitrosoaldicarb: Project No. 810C21. Method dated Apr 28, 1978. (Unpublished study received Nov 14, 1979 under 1016-69; submitted by Union Carbide Corp., Arlington, Va.; CDL:241324-F) 60193 Union Carbide Corporation (1973) Full Reports of Investigations Made with Respect to the Safety of the Pesticide Chemical: Temik. Summary of studies 093778-B through 093778-E. (Unpublished study received Jun 25, 1973 under 3F1414; CDL: 093778-A) Page 97 of 191 ------- 60194 Weil, C.S. (1972) Miscellaneous Toxicity Studies: Special Report 35-41. (Unpublished study received Jun 25, 1973 under 3F1414; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, D.C.; CDL:093778-B) 60195 Weil, C.S.; DeMary, L.J.; Soo, V. (1971) Comparative Skin Penetration Toxicity of Temik 10GV, Temik 15GV and 5 Other Pesticide Formulations as Marketed: Special Report 34-76. (Unpublished study received Jun 25, 1973 under 3F1414; prepared by CarnegieMellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, D.C.; CDL: 093778-C) 60196 Weil, C.S.; Woodside, M.D.; Bernard, J.R.; et al. (1973) Aldicarb (A), Aldicarb sulfoxide (ASO), Aldicarb sulfone (ASOI2) and a 1:1 Mixture of ASO:ASOI2: Two Year Feeding in the Diet of Rats: Special Report 35-82. (Unpublished study received Jun 25, 1973 under 3F1414; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, D.C.; CDL:093778-D) 60197 Weil, C.S.; Woodside, M.D.; Chin, B.H.; et al. (1973) Aldicarb: 2-Methylthio-2- methyrpropionaldehyde N-methylcarbamoyloxime: Seven-Day Inclusion in Diet of Dogs: Special Report 36-33. (Unpublished study received Jun 25, 1973 under 3F1414; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, D.C.; CDL:093778-E) 60554 West, J.S.; McGee, M. (1965) Special Report: The Single Dose Peroral Toxicity of Compounds 20299, 21149, 19786 and 20047A for White Leghorn Cockerels: Special Report 28-30. (Unpublished study received Jun 1, 1965 under unknown admin, no.; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:128692-F) 60555 Borash, A. J. (1965) Test Report on Union Carbide Agricultural Products. (Unpublished study received Jun 1, 1965 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, Va.; CDL:128692-G) 60556 Cope, O.B. (1964) Letter sent to Robert G. Harris dated Oct 30, 1964 Toxicity of various pesticides to rainbow trout and bluegill sunfish. (U.S. Fish and Wildlife Service, Fish- Pesticide Research Laboratory; unpublished study; CDL:128692-H) 61078 Mulla, M.S. (1964) Letter sent to R.G. Haines dated Oct 20, 1964 Information on toxicity of some compounds against mosquito fish. (Unpublished study received Oct 20, 1964 under unknown admin, no.; prepared by Univ. of California-Riverside, Div. of Agricultural Sciences, Citrus Research Center and Agricultural Experiment Station, Dept. of Entomology, submitted by Union Carbide Corp., Arlington, Va.; CDL: 131936-A) 61079 Union Carbide Corporation (1969) Toxicity of the Formulated Product Temik 10G Aldicarb Pesticide. (Unpublished study received on unknown date under unknown admin, no.; CDL:131936-C) 61080 Union Carbide Corporation (1968) Effect on Wildlife. Summary of studies 131936-A, 131936-B and 131936-H. (Unpublished study received on unknown date under unknown admin, no.; CDL:131936-E) 61081 Union Carbide Corporation (1968) Metabolism and Toxicity of Metabolites. (Unpublished study received on unknown date under unknown admin, no.; CDL: 131936-F) 61082 Union Carbide Corporation (1968) Acute Toxicity Studies. (Unpublished study received on unknown date under unknown admin, no.; CDL: 131936-G) Page 98 of 191 ------- 61087 Carpenter, C.P.; Goldberg, M.E.; Johnson, H.E.; et al. (1966) Special Report: Recapitulation of Acute Toxicity and Pharmacodynamic Studies on Dessin (Compound 19786): Report 29- 47. (Unpublished study received Sep 1, 1966 under 1016-EX-18; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:126458-D) 61089 Borash, A.J.; Bryant, H.M., Jr. (1965) Test Report on Union Carbide Agricultural Products. (Unpublished study received Jun 10, 1965 under 1016-EX-18; submitted by Union Carbide Corp., Arlington, Va.; CDL:126458-K) 62512 Union Carbide Corporation (19) Human Exposure Experience. (Unpublished study received Oct20, 1964 under unknown admin, no.; CDL:131936-D) 63184 Union Carbide Corporation (1968) The Name, Chemical Identity, and Composition of the Pesticide Chemicals. (Unpublished study received Jun 14, 1978 under 1016-81; CDL:234234- A) 63185 Union Carbide Corporation (19) Manufacturing Process. (Unpublished study received Jun 14, 1978 under 1016-81; CDL:234234-B) 63186 Union Carbide Corporation (19) Specification: Temik TSX Granular Pesticide. (Unpublished study received Jun 14, 1978 under 1016-81; CDL:234234-C) 63187 Union Carbide Corporation (19) Specification Methods: Temik TSX Granular Pesticide. (Unpublished study received Jun 14, 1978 under 1016-81; CDL:234234-D) 64115 Natoff, I.L. (1976) The effects of antidotes in experimental animals intoxicated by carbomate and organophosphorus cholinesterase inhibitors. Pages 53-64,InMed. Prot. Chem.-Warf. Agents, Pap. Symp.. By Stockholm, Sweden: Almquist & Wiksell. (Alsolnunpublished submission received Jul 20, 1980 under 1016-69; submitted by Union Carbide Corp., Arlington, Va.; CDL: 234481-A) 64811 Union Carbide Corporation (1977) Reasonable Grounds in Support of the Application for Registration of Standak 75 WP Sulfocarb Pesticide for Use on Tobacco and Cotton. (Reports by various sources; unpublished study received Aug 4, 1977 under 1016-79; CDL:231504-G) 65956 Johnson, H.E.; McGee, M.A.; Sullivan, L.J. (1968) Studies on an Effective Therapy for Overdoses of Temik, Temik Sulfoxide, and Temik Sulfone in the Rat: Special Report 31-139. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:229032-H) 66341 U.S. Environmental Protection Agency, Environmental Research Laboratory (1981) Acephate, Aldicarb, Carbophenothion, DBF, EPN, Ethoprop, Methyl Parathion, and Phorate: Their Acute and Chronic Toxicity, Bioconcentration Potential, and Persistence as Related to Marine Environments: EPA-600/4-81-023. (Unpublished study) 66588 Chin, B.H.; Sullivan, L.J. (1968) (Some Biomedical Considerations of Temik, Temik Sulfoxide and Temik Sulfone). (Unpublished paper #121 presented at the 156th ACS National Meeting, Agr. & Food Chemistry Div., Pesticide Subdivision; Sept 9-13, 1968, Atlantic City, N.J.; unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:229032-I) 66769 Peoples, S.A.; Maddy, K.T.; Smith, C.R. (1977) Occupational Exposure to Temik (Aldicarb) As Reported by Physicians in California for the Years 1974 through 1976. (California, Dept. of Food and Agriculture, Worker Health and Safety Unit; unpublished study; CDL:232634-A) Page 99 of 191 ------- 66770 Natoff, I.L.; Reiff, B. (1973) Effect of oximes on the acute toxicity of anticholinesterase carbamates. Toxicology and Applied Pharmacology 25:569-575. (Also In unpublished submission received Dec 23, 1977 under unknown admin, no.; submitted by California, Dept. of Food and Agriculture, Sacramento, Calif.; CDL:232634-B) 67477 Union Carbide Corporation (1973) Efficacy of Various Chemicals on Potatoes and Various Crops. (Compilation; unpublished study, including published data, received Nov 13, 1973 under 3F1414; CDL:093780-A) 68243 Union Carbide Corporation (1977) Nature of the Residue. Summary of studies 231503-B through 231503-Z. (Unpublished study received Aug 4, 1977 under 1016-79; CDL:231503- A) 68248 Borash, A.J.; Kramer, J.A., Jr.; Moorefield, H.H. (1973) Experiments Designed to Trace Movements of Aldicarb in Soil: UCC Project Report No. 17959. (Unpublished study received Aug 4, 1977 under 1016-79; submitted by Union Carbide Corp., Arlington, Va.; CDL:231503-P) 68249 Coppedge, J.R.; Ridgway, R.L.; Bull, D.L. (1968) A Preliminary Report on the Movement and Persistence of Aldicarb in Soil. (U.S. Agricultural Research Service, Entomology Research Div., unpublished study; CDL:231503-R) 68250 Richey, F.A., Jr.; Bartley, W.J. (1972) Temik Aldicarb Pesticide: Water Leaching of Aldicarb, Aldicarb Sulfoxide, Aldicarb Sulfone and Internal Standard Chloride Ion in Columns of Four Soil Types: UCC Project Report No. 16669. (Unpublished study received Aug 4, 1977 under 1016-79; submitted by Union Carbide Corp., Arlington, Va.; CDL:231503-S) 68251 Richey, F.A., Jr.; Moorefield, H.H. (1972) Temik-Aldicarb Pesticide: Upward Movement of Aldicarb through Soil during Water Evaporation: UCC Project Report No. 17526. (Unpublished study received Aug 4, 1977 under 1016-79; submitted by Union Carbide Corp., Arlington, Va.; CDL:231503-T) 68252 Romine, R.R.; Meeker, R.L. (1972) Temik Aldicarb Pesticide: Leaching of Aldicarb into Sandy Soil with Irrigation of a Temik Treated Sugar Beet Field: UCC Project Report No. 17079. (Unpublished study received Aug 4, 1977 under 1016-79; submitted by Union Carbide Corp., Arlington, Va.; CDL:231503-U) 69644 Union Carbide Corporation (1981) Reassessment of the Acceptable Daily Intake Values for TemikA(R)I (Aldicarb) and Metabolites in the Human. (Unpublished study received on unknown date under 264-330; CDL:244421-A) 69736 Dernehl, C.U. (1974) Letter sent to Richard C. Back dated Jan 21, 1974 Human consumption of potatoes containing 1 ppmof aldicarb. (Unpublished study received on unknown date under 3F1414; submitted by Union Carbide Corp., Washington, D.C.; CDL:098300-A) 69738 Quick, Q.; Lovell, C.M. (1966) Temik Sulfoxide and Sulfone Stability: File No. 6135. (Unpublished study received on unknown date under 3F1414; submitted by Union Carbide Corp., Washington, D.C.; CDL:098300-C) 69739 Union Carbide Corporation (1973) A Method for the Determination of Total Toxic Aldicarb Residues in Potato Tubers by Gas Chromatography. Method designation ALDICARB-FPD- POT dated Feb 1973. (Unpublished study received on unknown date under 3F1414; CDL: 098300-D) Page 100 of 191 ------- 69740 Union Carbide Corporation (1973) A Method for the Determination of Total Toxic Aldicarb Residues in Peanuts by Gas Chromatography. Method designation ALDICARB-FPD-PNUT dated Feb 1973. (Unpublished study received on unknown date under 3F1414; CDL: 098300- E) 69741 Union Carbide Corporation (1973) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received on unknown date under 3F1414; CDL:098300-F) 69742 Union Carbide Corporation (1973) Temik 10G Aldicarb Pesticide. (Unpublished study received on unknown date under 3F1414; CDL: 098300-G) 69743 Union Carbide Corporation (1972) Temik 10G Aldicarb Pesticide Assay and Analysis for Impurities: File No. 300-21V5. (Unpublished study received on unknown date under 3F1414; CDL: 098300-H) 69744 Union Carbide Corporation (1973) Reasonable Grounds in Support of the Petition: (Temik 10G). (Unpublished study received on unknown date under 3F1414; CDL:098300-J) 69745 Weil, C.S., ed. (1972) Miscellaneous Toxicity Studies: Special Report 35-41. (Unpublished study received on unknown date under 3F1414; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, D.C.; CDL:098300-K) 69914 Union Carbide Corporation (1965) Introduction: Temik. Summary of studies 131905-B, 131905-F and 131905-G. (Unpublished study received Sep 8, 1965 under unknown admin. no.;CDL:131905-A) 69915 Smyth, H.F., Jr. (1965) Letter sent to R.G. Haines dated Jun 4, 1965 Toxicity information on compound 21149. Summary of studies 131905-C through 131905-G. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute, submitted by Union Carbide Corp., Arlington, Va.; CDL:131905-B) 69916 Striegel, J.A.; Condra, N.I.; Haun, C.C.; et al. (1962) Range Finding Tests on Compound 21149: Report 25-53. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute of Industrial Research, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:131905-C) 69917 Weil, C.S.; Woodside, M.D.; Bernard, I; et al. (1963) Results of Three Months of Inclusion of Compound 21149 in the Diet of Rats: Report 26-47. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL: 131905-D) 69918 Weil, C.S.; Woodside, M.D.; Bernard, I; et al. (1964) Results of a Three Generation Reproduction Study on Rats Fed Compound UC21149 in Their Diet: Report 27-158. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:131905-E) 69919 Carpenter, C.P.; Condra, N.; McGee, M.A. (1965) A 4-hour Test for Evaluation of Comparative Skin Penetration Hazard: Report 28-34. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL: 131905-F) Page 101 of 191 ------- 69920 Pozzani, U.C.; Kinkead, E.R. (1965) The Mechanical Attrition of Some Granular Pesticide Formulations: Report 28-35. (Unpublished study received Sep 8, 1965 under unknown admin. no.; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:131905-G) 69921 Heywood, D.L. (1965) Letter sent to R.G. Haines dated Jul 28, 1965 Data on metabolism of UC 21149 in animals and opinion on metabolic fate of UC 21149 in plants and animals. (Unpublished study received Sep 8, 1965 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, Va.; CDL:131905-H) 69922 Striegel, J.A.; Condra, N.I.; Haun, C.C. (1963) Comparison of the Acute Toxicity of Compound 21149 with Several of Its Analogues: Report 26-29. (Unpublished study received Sep 8, 1965 under unknown admin, no.; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL: 131905-1) 70515 Food and Agriculture Organization of the United Nations (1980) Pesticide Residues in Food-- 1979: Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues Held in Geneva, 3-12 December 1979. By FAO and World Health Organization. Rome, Italy: FAO. (Pages iii- iv,vi, 17-20 only; FAO plant production and protection paper 20; available from: Distribution and Sales Section, FAO, Via delle Terme di Caracalla, Rome 00100, Italy; published study; CDL:244431-A) 70984 Sontag, J.M. (1978) Minutes: Thirteenth Meeting of the Data Evaluation/Risk Assessment Subgroup of the Clearinghouse on Environmental Carcinogens. (U.S. National Institutes of Health, National Cancer Institute, Div. of Cancer Cause and Prevention; unpublished study; CDL:237727-D) 73205 Union Carbide Agricultural Products Company, Incorporated (1980) Acute Toxicity of Temik TSX Granular Formulation. Summary of studies 243546-B through 243546-1. (Unpublished study received Oct 23, 1980 under 264-319; CDL:243546-A) 73207 Ercegovich, C.D.; Rashid, K.A. (1977) Mutagenesis Induced in Mutant Strains ofSalmonella typhimuriumby Pesticides. (Unpublished study, including letter dated Sep 22, 1977 from C.D. Ercegovich to Tom Evrard, received Aug 24, 1979 under 1258-812; prepared by Pennsylvania State Univ., Pesticide Research Laboratory, submitted by Olin Corp., Stamford, Conn.; CDL:240890-C) 73306 Quarles, J.M.; Schenley, C.K.; Tennant, R.W. (1975) Use of a transplacental host-mediated culture system for assay of transformation by Nitroso compounds. IRCS Medical Science (Supplement) 3(10):22. (Alsolnunpublished submission received Nov 14, 1979 under 1016- 69; submitted by Union Carbide Corp., Arlington, Va.; CDL:241324-B) 73307 Lijinsky, W.; Elespuru, R.K. (1975) Mutagenicity and Carcinogenicity of N-Nitroso Derivatives of Carbamate Insecticides. (Unpublished study, including published data, received Nov 14, 1979 under 1016-69; prepared by Oak Ridge National Laboratory and Univ. of Tennessee, Oak Ridge Graduate School of Biomedical Sciences, submitted by Union Carbide Corp., Arlington, Va.; CDL: 241324-C) 73308 Blevins, R.D.; Lijinsky, W., Regan, J.D. (1977) Nitrosated Methylcarbamate insecticides: Effect on the DNA of human cells. Mutation Research 44:1-7. (Alsolnunpublished submission received Nov 14, 1979 under 1016-69; submitted by Union Carbide Corp., Arlington, Va.; CDL:241324-D) Page 102 of 191 ------- 73309 Lijinsky, W.; Schmahl, D. (1978) Carcinogenicity of N-Nitroso derivatives of N- Methylcarbamate insecticides in rats. Ecotoxicology and Environmental Safety 2:413-419. (Alsolnunpublished submission received Nov 14, 1979 under 1016-69; submitted by Union Carbide Corp., Arlington, Va.; CDL:241324-H) 73345 Kimmerle, (1971) Letter sent to PF-ATEA Product Development dated Jan 25, 1971: Disyston and Temik granular: Report No. 29378. (Unpublished study received Dec 15, 1976 under 3125-58; prepared by Bayer, W. Germany, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:095640-E) 75794 West, J.S.; McGee, M. (1965) The Single Dose Peroral Toxicity of Compounds 20299, 21149, 19786 and 20047A for White Leghorn Cockerels: Report 28-30. (Unpublished study received Aug 8, 1966 under 7G0529; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., South Charleston, W.Va.; CDL:090633-G) 75801 Carpenter, C.P.; Goldberg, M.E.; Johnson, H.E.; et al. (1966) Recapitulation of Acute Toxicity and Pharmacodynamic Studies on Dessin (Compound 19786): Report 29-47. Summary of studies 09063 3-C through 090633-1. (Unpublished study received Aug 8, 1966 under 7G0529; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., South Charleston, W.Va.; CDL:090633-S) 76065 Knott, W.; Beliles, R.P. (1966) UC-21149: Acute Toxicity in Sunfish. (Unpublished study received Jul 26, 1966 under 1016-69; prepared by Woodard Research Corp., submitted by Union Carbide Corp., Arlington, Va.; CDL:231174-A) 76066 Woodard Research Corporation (1965) UC-21149: Safety Evaluation on Fish and Wildlife: (Bobwhite Quail and Rainbow Trout). (Unpublished study received Jul 26, 1966 under 1016- 69; submitted by Union Carbide Corp., Arlington, Va.; CDL:231174-B) 76067 Beliles, R.P.; Knott, W.; Wright, L. (1966) UC-21149 10%: Summary of Safety Evaluation on Fish and Wildlife. Summary of studies 231174-A and 231174-B. (Unpublished study received Jul 26, 1966 under 1016-69; prepared by Woodard Research Corp., submitted by Union Carbide Corp., Arlington, Va.; CDL:231174-D) 76100 Dernehl, C.U. (1966) Letter sent to J.S. Leary, Jr. dated Jul 12, 1966 Acute poisoning report by UC 21149. (Unpublished study received Jul 26, 1966 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, Va.; CDL: 102773-A) 79137 Enfield, C.G.; Carsel, R.F.; Cohen, S.Z.; et al. (1980) Methods of Approximating Transport of Organic Pollutants to Groundwater. (Unpublished study received Jun 24, 1981 under 100-607; prepared by U. S. Environmental Protection Agency, Office of Pesticide Programs, Hazard Evaluation Div. and Computer Science Corp., submitted by Ciba-Geigy Corp., Greensboro, N.C.;CDL:245315-B) 79162 Wacker Chemie GmbH (1979) Toxicology Data for Butocarboxime and Drawin 4E: Summary. Summary of studies 245338-D through 245338AB. (Unpublished study received Jun25, 1981 under 35902-EX-l; CDL:245338-C) 79566 Kinkead, E.R.; Chin, B.H., Weil, C.S.; et al. (1968) Toxicity Studies on Temik and Related Carbamates: Special Report 3148. (Unpublished study received Jan 18, 1977 under 1016-EX- 37; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:229032-D) 79604 Wacker Chemie GmbH (1974) The Metabolism of Butocarboxime. (Unpublished study received 1975 under 35902-1; CDL:227600-A) Page 103 of 191 ------- 79867 Union Carbide Corporation (1966) Evaluation of lexicological Data for Registration of Temik, Brand of Pesticide (UC-21149) Submitted with Letter of Octobers, 1966. (Unpublished study received Dec 6, 1966 under 1016-EX-24; CDL:106627-A) 80223 Abdalla, N. A. (1981) Letter sent to J. Steve Lovell dated Jul 23, 1981: Grain sorghum fractionation studies. (Unpublished study received Jul 31, 1981 under 8F2107; submitted by Union Carbide Corp., Arlington, Va.; CDL:070212-A) 80696 Smyth, H.F., Jr. (1966) Letter sent to H.A. Stansbury, Jr. dated Dec 1, 1966 Summary of toxicity information on compound 21149. Summary of studies 090072-C through 090072-E, 090072-G, 090072-H, 090072-N, 090072-Q, 090072-R and 090072-T. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-A) 80697 Andrawes, N.R.; Dorough, H.W.; Lindquist, D.A. (1966) Degradation and Elimination of Temik 2-Methyl-2-(methylthio)propionaldehyde O-(Methylcarbamoyl)oxime in Rats. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Texas A & M Univ., Dept. of Entomology, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072- B) 80698 West, J.S.; Weil, C.S.; McGee, M.; et al. (1966) Temik (Compound 21149, Technical, 2- Methylthio-2-methylpropionaldehyde N-Methylcarbamoyloxime) Joint Action with Selected Organic Phosphate and Carbamate Pesticides: Report 29-98. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-A) 80699 Johnson, H.E.; McGee, M.A.; King, J.M. (1966) Temik (Technical Grade Compound 21149) Demyelination Potential in Chickens: Report 29-90. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-D) 80700 Johnson, H.E. (1966) Temik (Technical Grade Compound 21149): Comparative Behavioral Effect in Rats: Report 29-89. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL: 090072-E) 80701 Carpenter, C.P.; Condra, N.I.; Humes, C; et al. (1966) Temik 10G (10.5% Granular Formulation of Compound 21149): 15-day Dermal Applications to Rabbits: Report 298-80. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-G) 80702 Sexton, R. J. (1966) Toxicity of TemikA(R)I. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-J) 80703 Ketcham, N.H. (1966) Agricultural Chemicals: Analyses of Urine Specimens for Metabolite of UC21149: Project No. 299A20. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-K) 80704 Peele, R.E. (1966) Industrial Hygiene-Air Pollution Evaluation of Hazards Associated with the Production of Compound 21149 & Formulation of Temik 10-G Insecticide: Report No. 66-IH-158-I-1. Includes methods dated Apr 26, 1966 and Jun 17, 1964. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.V.; CDL:090072-L) Page 104 of 191 ------- 80705 Williams, F. (1966) Letter sent to J.T. Adams, R.C. Back, D.F. Braun, et al. dated Jun 2, 1966: Human exposure study in the field application of Temik 10G on cotton. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-M) 80706 Beliles, R.P.; Knott, W.; Wright, L. (1966) UC-21149: Safety Evaluation on Fish and Wildlife: (Bobwhite Quail and Rainbow Trout). (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Woodard Research Corp., submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-O) 80707 Knott, W.; Beliles, R.P. (1966) UC-21149: Acute Toxicity in Sunfish. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Woodard Research Corp., submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-P) 80708 West, J.S.; Condra, N.I. (1966) Miscellaneous Acute Toxicity Data, Olefins Division: Report 28-140. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie- Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-S) 80709 Knaak, J.B.; Sullivan, L.J.; Tallant, M.J.; et al. (1965) Metabolism of UC 21149 in the Rat: Report 28-138. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by CarnegieMellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-T) 80710 Carpenter, C.P.; Goldberg, M.E.; Johnson, H.E.; et al. (1965) Recapitulation of Pharmacodynamic and Acute Toxicity Studies on Temik (Compound 21149): Report 28-78. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-V) 80808 Union Carbide Corporation (1965) Introduction: Temik: Toxicity. Summary of study 090525- B. (Unpublished study received Jan 25, 1966 under 6G0473; CDL:090525-A) 80809 Smyth, H.F., Jr. (1966) Letter sent to R.G. Haines dated Jan 25, 1966 Summary of toxicity reports on compound 21149. Summary of studies 090525-C through 090525-G, 090525-J through 090525-N and 090527-J. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-B) 80810 Striegel, J.A.; Condra, N.I.; Haun, C.C.; et al. (1963) Range Finding Tests on Compound 21149 (2-Methylthio-2-methylpropionaldehyde N-Methylcarbamoyloxime): Report 25-53. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute of Industrial Research, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-C) 80811 Carpenter, C.P.; Condra, N.; McGee, M.A. (1965) A 4-hour Test for Evaluation of Comparative Skin Penetration Hazard: Report 28-34. (Unpublished study received Jan 25, 1965 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-F) 80812 West, J.S.; McGee, M. (1965) The Single Dose Peroral Toxicity of Compounds 20299, 21149, 19786 and 20047A for White Leghorn Cockerels: Report 28-30. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL: 090525-J) Page 105 of 191 ------- 80813 Knaak, J.B.; Sullivan, L.J.; Tallant, M.J.; et al. (1965) Metabolism of UC 21149 in the Rat: Report 28-138. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-L) 80814 Carpenter, C.P. (1966) Letter sent to R.G. Haines dated Jan 25, 1966: 2 year feeding of UC 21149 (409-RD-89 reference 14LK90) to dogs. (Unpublished study received Jan 25, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-N) 80815 Union Carbide Corporation (1965) Residue Data: UC 21149. (Compilation; unpublished study received Jan 25, 1966 under 6G0473; CDL:090525-O) 80816 Romine, R.R. (19) The Determination of Residues of 2-Methyl-2(methylthio) Propionaldehyde O-(Methylcarbamoyl) Oxime, Systemic Insecticide UC 21149, in Agricultural Crops. Undated method. (Unpublished study received Jan 25, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-P) 80817 Crowder, R.A.; Johnson, H.E.; Romine, R.R. (1965) Letter sent to J.T. Adams; D.L. Heywood; R.C. Back; et al. dated Jul 14, 1965: The response of Temik metabolites and related materials to the method of analysis employed for Temik systemic insecticide. (Unpublished study received Jan 25, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-Q) 80818 Stansbury, H.A.; Johnson, D.P. (1964) Agricultural Chemicals, Residue Analysis: Stability of 3-Chloro-5(or 6)-endo-cyanobicyclo(2.2.1)heptan-2-one N-Methylcarbamoyloxime (20047) and 2Methyl-2-methylthiopropionaldehyde N-Methylcarbamoyloxime (21149) in Animal Diets: Project No. 143B15. (Unpublished study received Jan 25, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:09525-R) 80819 Union Carbide Corporation (1966) Metabolism of 21149 in Cotton and Potatoes. (Unpublished study received Jan 25, 1966 under 6G0473; CDL:090525-S) 80820 Coppedge, J.R.; Lindquist, D.A. (19) Preliminary Studies on the Fate of Radiolabeled Union Carbide 21149 in Soil and Cotton Plants. (U.S. Agricultural Research Service, Entomology ResearchDiv.; unpublished study; CDL:09525-T) 80821 Romine,R.R. (1966) Letter sent to R.G. Haines dated Jan 11, 1966 Interpretation of analytical results obtained by Temik residue method for agricultural crops. (Unpublished study received Jan 25, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-U) 80822 U.S. Public Health Service (1966) Report of Illness Associated with Use of the Experimental Insecticide, Temik. (Communicable Disease Center, Western Pesticides Research Laboratory; unpublished study; CDL:090527-B) 80823 Herrett, R.A.; Borash, A.J. (1967) Temik Insecticide: Root Uptake, Distribution, and Disappearance of Temik in Spearmint and Bean: Project No. 11 IB 16. (Unpublished study, including letters dated Feb 7, 1967 from R.A. Herrett to H.A. Stansbury and May 20, 1967 fromH.A. Stansbury, Jr. to Harry W. Hays, received Mar 11, 1968 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090527-C) 80824 Durham, W.F. (1967) Letter sent to Chief, Office of Pesticides dated Jan 7, 1967: Quarterly memorandum of research progress, Western Pesticides Research Laboratory, for period October-December, 1966. (U.S. Public Health Service, Communicable Disease Center, Office of Pesticides, Western Pesticides Research Laboratory; unpublished study; CDL:090527-D) Page 106 of 191 ------- 80825 Carpenter, C.P.; Condra, N.I.; Humes, C.; et al. (1966) Temik 10G (10.5% Granular Formulation of Compound 21149): 15-day Dermal Applications to Rabbits: Report 29-80. (Unpublished study received Mar 11, 1968 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp, New York, N.Y.; CDL:090527-I) 81182 Interregional Research Project Number 4(1977) Reasonable Grounds in Support of the Petition: (Temik). (Unpublished study received Aug 10, 1977 under 7E1996; CDL:097784-A) 81413 Weil, C.S.; Mazzoni, M.; Condra, N.I.; et al. (1966) Results of Long-term Tests for Mouse Skin Carcinogenicity of Three Process Residues, One Epoxide and Three Compounds: Report 29-34. (Unpublished study received Jul 26, 1966 under 1016-EX-24; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:126498-A) 81414 Knaak, J.B.; Sullivan, L.J.; Tallant, M.J.; et al. (1965) Metabolism of UC 21149 in the Rat: Report 28-138. (Unpublished study received Jan 14, 1966 under 1016-EX-24; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:126498-B) 81415 Pozzani, U.C.; Haun, C.C.; Kinkead, E. (1963) A Basis for Projecting the Probable Inhalation Hazards of UC 21149 to Humans under Field Use Conditions: Report 26-38. (Unpublished study received Jan 14, 1966 under 1016-EX-24; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:126498-C) 81550 Great Lakes Chemical Corporation (1978) Ethylene Dibromide and Its Pesticidal Aternatives- -Toxicity, Persistence, and Plant Residues. (Unpublished study received Jan 26, 1979 under 5785-18; CDL:097779-Q) 81880 Stansbury, H.A.; Johnson, D.P. (1964) Stability of... (20047) and ... (21149) in Animal Diets: File No. 2323. (Unpublished study received Jun 6, 1966 under 5G0452; submitted by Union Carbide Corp., New York, N.Y.; CDL:090493-X) 81883 Union Carbide Corporation (1965) Toxicity to Fish and Wildlife. (Compilation; unpublished study received May 10, 1965 under 5G0452; CDL:090494-B) 85455 Herrett, R.A.; Bagley, W.P. (1966) Insecticide Temik: Metabolism and Distrubution in Potato: 855-31107-8020. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-F) 85456 Weil, C.S.; Bernard, J.; Woodside, M.D.; et al. (1966) Insecticide Temik: Teratogenic Potential in Rats: Report 29-81. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL: 090072-H) 85457 Bartley, W.J.; Heywood, D.L. (1966) Insecticide, Temik: Radiosynthesis of 2-Methyl-2- (methylthio) propionaldehyde o-(MethylCA14I-carbamoyl)oxime and Its Corresponding Sulfoxide: 85531106-8048. (Unpublished study received Mar 2, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-I) 85458 Weil, C.S.; Woodside, M.D.; Bernard, J.; et al. (1966) Two-year Feeding of Compound 21149 in the Diet of Dogs: Report 29-5. (Unpublished study received Mar 2, 1967 under 7F0573; prepared by Carnegie-Mellon Univ., Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090072-Q) Page 107 of 191 ------- 85460 Weil, C.S.; King, J.M.; Woodside, M.D.; et al. (1965) Two-year Feeding of Compound 21149 in the Diet of Rats: Report 28-123. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-K) 85461 Pozzani, U.C.; McGee, M.A.; Kinkead, E.R.; et al. (1966) Response of Rats Living for 28 Days on Topsoil Treated with UC21149 10G1: Report 29-2. (Unpublished study received Jan 25, 1966 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090525-M) 86606 Andrawes, N.A. (1981) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used: Temik. (Unpublished study received Nov 2, 1981 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:070447-A) 86607 Myers, W.R.; Harrison, S.L. (1981) Residues: TemikA(R)I/Grapes: Project No. 813C50. (Unpublished study received Nov 2, 1981 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:070447-B) 86608 Union Carbide Corporation (1978) Determination of Total Toxic Aldicarb Residues in Grapes by Gas Chromatography. Method Aldicarb-FPD-general dated Aug 1978. (Unpublished study received Nov 2, 1981 under 264-330; CDL:070447-C) 86609 Union Carbide Corporation (1977) Confirmatory Procedure for the Identification of Aldicarb Residues Utilizing a Non-polar GLC Column. Method Aldiccarb-FPD-confirmatory dated Feb 1977. (Unpublished study received Nov 2, 1981 under 264-330; CDL: 070447-D) 86610 Union Carbide Agricultural Products Company, Incorporated (1981) Reasonable Grounds in Support of the Petition: Temik. (Unpublished study received Nov 2, 1981 under 264-330; CDL: 070446-A) 90570 Union Carbide Corporation (1966) Temik(TM) 10G Experimental Systemic Pesticide: (Active Ingredient~UC 21149): F-40977C. (Unpublished study received Jul 26, 1966 under 1016-EX-30; CDL:131932-A) 90572 Union Carbide Corporation (1965) Available Toxicity Data. (Unpublished study received Sep 8, 1965 under unknown admin, no.; CDL:131945-A) 90573 Union Carbide Corporation (1965) Results of Tests Conducted by and under the Supervision of Federal and State Agencies with UC 21149 Formulations on Ornamental Plant Pest Control-1962-1964. (Compilation; unpublished study received Sep 8, 1965 under unknown admin, no.; CDL:131945-B) 91233 Union Carbide Corporation (1965) Summary of Selected Performance of UC 21149 on Various Pests on Cotton and Potatoes 1964-1965. (Compilation; unpublished study received Jul 26, 1966 under 6G0473; CDL:090526-C) 91234 Union Carbide Corporation (1966) Summary and Discussion: Temik. (Compilation; unpublished study received Jul 26, 1966 under 6G0473; CDL:090526-D) 91235 Stansbury, H.A.; Wright, M.P. (1966) Insecticide, Temik: Standard Samples for Residue Analyses: 855-31106-7965. (Unpublished study received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-F) Page 108 of 191 ------- 91236 Williams, F. (1966) Letter sent to J.T. Adams, N.H. Ketcham, R.C. Back and others dated Jun 2, 1966: Human exposure study in the field application of Temik 10G on cotton. (Unpublished study received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-J) 91237 Union Carbide Corporation (19) Cholinesterase. Undated method. (Unpublished study received Jul 26, 1966 under 6G0473; CDL: 090526-K) 91238 Peele, R.E. (1966) Industrial Hygiene-Air Pollution Evaluation of Hazards Associated with the Production of Compound 21149 & Formulation of Temik 10-G Insecticide: Report No. 66-IH-158-I-1. Includes method 38C-21V5-R2.1 dated Apr 26, 1966 and method 38C-22M2- 22 dated Jun 17, 1966. (Unpublished study received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-L) 91239 Ketcham, N.H. (1966) Agricultural Chemicals: Analyses of Urine Specimens for Metabolite of UC21149: File No. 5882. (Unpublished study received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-M) 91240 Sexton, R.J. (1966) Toxicity of TemikA(R)I. (Unpublished study, including letter dated Jul 11, 1966 from R.J. Sexton to L.B. Weddell, received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-N) 91241 West, J.S.; Condra, N.I. (1966) Miscellaneous Acute Toxicity Data: Report 28-140. (Unpublished study received Jul 26, 1966 under 6G0473; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-R) 91242 Dernehl, C.U. (1966) Letter sent to J.S. Leary, Jr. dated Jul 12, 1966 Human poisoning by UC 21149, Temik 10G. (Unpublished study received Jul 26, 1966 under 6G0473; submitted by Union Carbide Corp., New York, N.Y.; CDL:090526-W) 91958 Ridgway, R.L.; Cowan, C.B. (1966) A Report on Laboratory and Field Studies on the Effect of Several Insecticides on Beneficial Arthropods in 1966: Mobay 20268. (U.S. Agricultural Research Service, Entomology Research Div., Cotton Insects Systemic Chemicals Investigations and Southwestern Cotton Insects Investigations; unpublished study; CDL: 120463-D) 92405 Borash, A. J. (1965) Test Report on Union Carbide Agricultural Products. (Unpublished study received Sep 8, 1965 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, Va.; CDL:131946-A) 92605 Abdellatif, M.A.; Hermanson, H.P.; Reynolds, H.T. (1967) Effect of soil clay and organic matter content upon systemic efficacy of two carbamate insecticides. Journal of Economic Entomology 60 (5): 1445-1450. (Also In unpublished submission received Sep 25, 1968 under 8F0711; submitted by FMC Corp., Middleport, N.Y.; CDL:091231-C) 92769 Lin, S.C.; Funke, B.R.; Schulz, J.T. (1972) Effects of some organophosphate and carbamate insecticides on nitrification and legume growth. Plant and Soil 37:489-496. (Also in unpublished submission received Mar 30, 1977 under 279-2712; submitted by FMC Corp., Philadelphia, Pa.; CDL:229241-E) 93021 Union Carbide Corporation (1966) Temik 10G Experimental Systemic Pesticide (Active Ingredient~UC 21149). New York, N.Y.: Union Carbide. (F-40977C, Mar 1966; also in unpublished submission received Oct 20, 1967 under 1016-EX-30; CDL:131932-A) Page 109 of 191 ------- 93628 Union Carbide (1967) Summary: Toxicological Studies on Temik. Summary of study 090714-C. (Unpublished study received on unknown date under 8F0637; CDL:090714-A) 93629 Union Carbide (1967) Summary and Discussion: Temik Residue Studies. Includes methods dated Aug 18, 1967. (Compilation; unpublished study received on unknown date under 8F0637; CDL: 090714-D) 93630 Union Carbide (1966) Summary of Data on Metabolism of Temik in the Cotton Plant. Summary of study 090714-G. (Unpublished study received Dec 29, 1966 under 8F0637; CDL:090714-F) 93631 Union Carbide (1967) Performance Data: Temik 10G~Cotton. (Compilation; unpublished study received on unknown date under 8F0637; CDL:090714-H) 93632 Haines, R.G. (1967) TemikA(TM)110G Experimental Systemic Pesticide: F-40977D. (Unpublished study received on unknown date under 8F0637; submitted by Union Carbide, South Charleston, W.Va.; CDL:090714-I) 93640 Coppedge, J.R.; Lindquist, D.A.; Bull, D.L.; et al. (1966) A Report on 2-Methyl-2- (methylthio)propionaldehydeO(methylcarbamoyl)oxime (Temik) in Cotton Plants and Soil. (Unpublished study received Feb 27, 1967 under 7F0573; prepared by Texas A & M Univ., Agricultural Experiment Station, Entomology Research Div., submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090741-B) 93641 Borash, A.J. (1966) Insecticide, Temik: Relative Soil Persistence of Sulfide, Sulfoxide, and Sulfone: Status Report 855-311078157. (Unpublished study received Feb 27, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL: 090741-C) 93642 Coppedge, J.R. (1967) Fate of 2-Methyl-2-(methylthio)propionaldehydeO- (methylcarbamoyl)oxime (Temik) in Plants and Soil. Master's thesis, Texas A & M Univ. (Unpublished study received Feb 27, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090741-D) 93643 Stansbury, H.A.; Wright, M.P. (1966) Insecticide, Temik: Standard Samples for Residue Analyses: Status Report 855-31106-7965. (Unpublished study received Feb 27, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, W.Va.; CDL:090741-E) 93644 Union Carbide Corporation (1966) Summary and Discussion of Results of Tests with Temik 10G on Potatoes 1965-1966. (Compilation; unpublished study received Feb 27, 1967 under 7F0573; CDL: 090741-F) 93645 Bull, D.L.; Lindquist, D. A.; Coppedge, J.R. (1966) A Report on Metabolism of 2-Methyl-2- (methylthio)propionaldehydeO-(methylcarbamoyl)oxime (Temik) in Insects. (U.S. Agricultural Research Service, Entomology Research Div., Cotton Insects Systemic Chemicals Investigations; unpublished study; CDL:090741-G) 93913 Westlake, G.E.; Bunyan, P.J.; Martin, A.D.; et al. (1981) Carbamate poisoning: Effects of selected carbamate pesticides on plasma enzymes and brain esterases of Japanese quail (Coturnix cotornix japonica). Journal of Agricultural and Food Chemistry 29(4):779-784. (Alsolnunpublished submission received Jan 26, 1982 under 239-2471; submitted by Chevron Chemical Co., Richmond, Calif.; CDL:246657-J) 94799 Me, D.A. (1981) Letter sent to Donald Stubbs dated Oct 28, 1981 Concerning the use of Aldicarb to control citrus nematodes in grapefruit orchards. (Texas, Dept. of Agriculture, Agricultural & Environmental Sciences Div., unpublished study, including undated letter fromE.L. Johnson to David A. Me; CDL: 246256-A) Page 110 of 191 ------- 95927 Borough, H. W. (1970) Metabolism of insecticidal methylcarbamates in animals. Journal of Agricultural and Food Chemistry 18(6): 1015-1022. (Alsolnunpublished submission received Jan 18, 1971 under 9F0843; submitted by Shell Chemical Co., Washington, D.C.; CDL:093138-AC) 96543 Union Carbide Agricultural Products Company, Incorporated (1982) Monitoring Aldicarb Residues in Soil and Water, 1981. (Compilation; unpublished study received Mar 9, 1982 under 264-330; CDL:246960-A) 96544 Hansen, J.L.; Hendrix, C.D. (1982) Comments on Intera and Cornell Aldicarb Transport Simulation for Eastern Long Island: File No. 29840. (Unpublished study received Mar 9, 1982 under 264330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:246960-B) 96545 Andrawes, N.R. (1982) Response to EPA's Conclusions Relative to Aldicarb Environmental Fate: Project No. 813C51. (Unpublished study received Mar 9, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL: 246960-C) 96546 Andrawes, N.R.; Heintzelman, R.W. (1982) Plant Uptake of TemikA(R)I Aldicarb Pesticide from Soil: File No. 29920. (Unpublished study received Mar 9, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL: 246960-D) 96547 Spiegel, M.H.; Conway, R. A. (1982) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide, and Aldicarb Sulfone: Project III. (Unpublished study received Mar 9, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:246960-E) 96548 Hansen, J.L. (1982) Letter sent to R.C. Back dated Feb 19, 1982: Hydrolysis interpolations: Project Ilia. (Unpublished study received Mar 9, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL:246960-F) 96549 Technicon Industrial Systems (1981) Preliminary Method for the Determination of Aldicarb and Its Oxidative Methabolities (sic) in Potable Water as Total Aldicarb Sulfone Equivalence. (Unpublished study, including letters dated Nov 16, 1981 from T.M. Martin to K.A. Mede and Nov 18, 1981 from J.C. Daly to T.M. Martin, received Mar 9, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, Pa.; CDL: 246960-G) 96550 Union Carbide Agricultural Products Company, Incorporated (1982) A Rating System for Predicting the Appearance of Aldicarb Residues in Potable Water. (Unpublished study received Mar 9, 1981 under 264-330; CDL:246960-J) 96557 Myers, W.R.; Harrison, S.L. (1982) Residues: TemikA(R)I/Tomatoes: File No. 29948. Includes method dated Aug 1977. (Unpublished study received Mar 9, 1982 under 8F2096; submitted by Union Carbide Corp., Arlington, Va.; CDL:070711-A) 98468 Stauffer Chemical Company (1980) Comparison of Acute Oral Avian Toxicology between DyfonateA(R)I 20-G Insecticide and Other Corn Granular Insecticides. (Unpublished study received Oct 24, 1980 under 476-2028; CDL:243582-A) 100230 Clarkson, V.A.; Haines, R.G.; Hennsley, W.H.; et al. (1969) Report on Additional Field Tests with Temik 10G Aldicarb Pesticide on the Potential Hazard to Bobwhite Quail. (Unpublished study received Oct 27, 1969 under 1016-EX-30; submitted by Union Carbide Corp., Arlington, Va.; CDL:126506-B) Page 111 of 191 ------- 100231 Lund, R.C.; Haines, R.G. (1969) Field Evaluation of Temik 10G Aldicarb Pesticide Potential Hazard to White-tail Deer and Cottontail Rabbits from Simulated Spills. (Unpublished study received Oct 27, 1969 under 1016-EX-30; prepared in cooperation with New Jersey, Fish and Game Commission, Black River State Game Field Station, submitted by Union Carbide Corp., Arlington, Va.; CDL:126506-C) 100232 Back, R.C. (1969) Letter sent to Harold G. Alford dated Aug 22, 1969: Temik 10G aldicarb pesticide-First periodic report. (Unpublished study received Aug 25, 1969 under 1016-EX- 30; submitted by Union Carbide Corp., Arlington, Va.; CDL:126506-D) 100296 Clarkson, V.A.; Hensley, W.H. (1968) Temik Insecticide: Toxicity of Temik, Temik Sulfoxide, and Temik Sulfone to Bluegill Sunfish: File No. 10493. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Arlington, Va.; CDL:096727-B) 100381 Union Carbide Corp. (1968) Feeding in the Diet of Rats for Three or Six Months: Report 31- 142. (Unpublished study received Jan 25, 1978 under 1016-79; CDL:096728-A) 100382 Striegel, J.; Condra, N.; Haun, C. (1963) Acute Toxicity of Compound (21865): Special Report 26-29. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-B) 100383 Weil, C.; Condra, N.; White, C. (1969) Temik Sulfone: Single Rabbit Skin Penetration Studies: Special Report 32-78. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-C) 100384 Nycum, J.; Kinkead, E.; Lauffer, J.; et al. (1968) Toxicity Studies on Temik (Sulfone): Special Report 31-48. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-D) 100385 Weil, C.; Condra, N.; Geary, D.; et al. (1973) UC 21865; Technical... Range Finding Toxicity Studies: Special Report 36-26. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-E) 100386 Weil, C. (1974) Miscellaneous Toxicity Studies: UC 21865: Special Report 37-10. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-F) 100387 Babish, J.; Salerno, A. (1977) Neurotoxicity Evaluation of UC 21865 in White Leghorn Hens (Gallus domesticus): Laboratory No. 5233. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Food and Drug Research Laboratories, Inc., submitted by Union Carbide Corp., Arlington, VA; CDL:096728-M) 100388 Woodside, M.; Weil, C.; Bernard, J.; et al. (1977) Aldicarb Sulfone: 18-month Feeding in the Diet of Mice: Project Report 4038. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Institute of Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-O) Page 112 of 191 ------- 100389 Weil, C. (1970) Miscellaneous Toxicity Studies: Temik: Special Report 33-18. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-T) 100390 Weil, C.; McGee, M.; Baughman, J. (1970) Sulfocarb: Miscellaneous Single Dose Peroral and Parenteral LD50 Assays and Some Joint Action Studies: Special Report 33-7. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-U) 100391 Weil, C. (1970) Miscellaneous Toxicity Studies: Temik: Special Report 33-92. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-V) 100392 Weil, C.; Condra, N.; Geary, D.; et al. (1973) UC 21865 Formulation 22RZB-75-B; 50W: Range Finding Toxicity Studies: Special Report 36-24. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Carnegie-Mellon Univ., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-X) 100393 Weil, C.; Burton, D.; Calisti, L. (1974) UC 21865 Technical, UC 21865-75% WP, Peroral Intubation of Rats with or without Subsequent Dose(s) of Atropine: Special Report 37-60. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by CarnegieMellonUniv., Div. of Sponsored Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-AA) 100394 Nycum, J.; Kinkead, E.; Lauffer, J.; et al. (1968) Toxicity Studies on the Probable Non- carbamate Plant Metabolites of Temik: Special Report 31-30. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096728-AB) 100398 Frazier, H. (1977) Sulfocarb Formulation Study. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Arlington, VA; CDL:096728-AH) 100401 Stier, E. (1971) Summary on Sensory Evaluation of Potato Samples: Temik. (Unpublished study received Jan 25, 1978 under 101679; prepared by Rutgers Univ., Dept. of Food Science, submitted by Union Carbide Corp., Arlington, VA; CDL:096734-C) 100402 Stier, E. (1972) Sensory Evaluation Report on Peanuts. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Rutgers Univ., submitted by Union Carbide Corp., Arlington, VA; CDL:096734-D) 100403 Holland, R. (1976) Letter sent to A. Dawson dated Oct 5, 1976: Taste test: Effect of experimental pesticide on Valencia orange flavor. (Unpublished study received Jan 25, 1978 under 101679; prepared by Sunkist Growers, Inc., submitted by Union Carbide Corp., Arlington, VA; CDL:096734-E) 100404 Foremost Foods Co. (1977) Difference Testing: Kidney Beans: Control Versus Temik Treated. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Arlington, VA; CDL:096734-F) Page 113 of 191 ------- 100405 Foremost Research Center (1977) Difference Testing: Fresh Tomatoes—Control Versus Temik Treated: Tomato Juice-Control Versus Temik Treated: Tomato Paste-Control Versus Temik Treated. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Arlington, VA; CDL:096734-G) 100406 Vieira, M. (1977) Letter sent to P. Schroeder dated Jul 19, 1977 Efficacy of Temik in coffee beans. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Union Carbide de Brasil S.A., submitted by Union Carbide Corp., Arlington, VA; CDL:096734-H) 100407 Ough, C. (1977) Letter sent to P. Darst dated Feb 1, 1977 Results of wine tasting: Temik treated grapes. (Unpublished study received Jan 25, 1978 under 1016-79; prepared by Univ. of California-Davis, Dept. of Viticulture and Enology, Agricultural Experiment Station, submitted by Union Carbide Corp., Arlington, VA; CDL:096734-I) 100408 Union Carbide Corp. (1976) Animal Feeding Acceptance: Temik 10G. Summary of study 096734-K. (Unpublished study received Jan 25, 1978 under 1016-79; CDL:096734-J) 100409 Haines, R. (1970) Field Evaluations of Potential Hazard of Temik 10G Aldicarb Pesticide to Valley Quail and Ring-necked Pheasants: Trial Two. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Arlington, VA; CDL:096734-K) 100694 Intera Environmental Consultants, Inc. (1982) Effects of Varying Input Load and Degradation Rates on Simulated Regional Movement of Aldicarb in Ground Water in Long Island. Rev. (Unpublished study received May 5, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL: 247403-A) 101902 Union Carbide Corp. (1970) The Name, Chemical Identity and Composition of the Pesticide Chemical: Aldicarb. (Compilation; unpublished study received Apr 12, 1971 under 1016-69; CDL:005151-A) 101903 Union Carbide Corp. (1971) Efficacy of Temik on Various Crops. (Compilation; unpublished study received Apr 12, 1971 under 1016-69; CDL:005151-B) 101904 Union Carbide Corp. (1966) Temik 10G Experimental Systemic Pesticide (Active Ingredient- -UC 21149): Technical Information for Testing Purposes: F-40977C. Summary of studies 005593-A through 005593-C and 005594-B. (Unpublished study received Jul 19, 1966 under 1016-69; CDL:005592-A) 101905 Union Carbide Corp. (1969) Transfer of Aldicarb from Temik 10G to Untreated Corn Cob Grits under Varied Temperature and Humidity Conditions. (Unpublished study received Nov 24, 1969 under 1016-69; CDL:024305-A) 101906 Union Carbide Corp. (19) Shelf Life of Temik 10G. (Unpublished study received Oct 29, 1969 under 1016-69; CDL:024310-C) 101907 Ridgway, R.; Stokes, R.; Coppedge, J. (1969) Laboratory Evaluations of Release Characteristics of Various Carbon Based Granular Formulations of Aldicarb (Temik). (U.S. Agricultural Research Service, Entomology Research Div.; unpublished study; CDL:024310- D) 101908 Back, R. (1969) Netherlands and Germany: Temik 10G Marketing: Summary Report. (Unpublished study received on unknown date under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:024310-E) Page 114 of 191 ------- 101909 Union Carbide Corp. (1969) Temik Aldicarb Pesticide: The Potential Hazard from Ingestion of Treated Plant Tissue. (Unpublished study received Nov 5, 1969 under 1016-69; CDL:024310-F) 101910 Union Carbide Corp. (1973) Residues: Temik 10G and Temik 15G. (Unpublished study received Jun21, 1974 under 1016-78; CDL: 026641-A) 101911 Haines, R. (1971) Ingestion of Aldicarb by Human Volunteers: A Controlled Study of the Effects of Aldicarb on Man. (Unpublished study received Apr 12, 1971 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:050847-A) 101912 Union Carbide Corp. (1971) (Toxicity Studies of Temik 10G on Humans). (Compilation; unpublished study received Apr 12, 1971 under 1016-69; CDL:050847-B) 101913 Dernehl, C. (1971) Letter sent to R. Back dated Mar 30, 1971 Temik use on ornamentals. (Unpublished study received Apr 12, 1971 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:050847-C) 101914 Weil, C.; McGee, M.; Baughman, J. (1970) Comparative Skin Penetration Toxicity of Temik 10GV and 15 Other Pesticide Formulations As Marketed: Special Report 33-15. (Unpublished study received Apr 12, 1971 under 1016-69; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:050847-D) 101915 Union Carbide Corp. (1970) Temik 10G Aldicarb Pesticide: Nature and Magnitude of Residues in Certain Ornamental Plants, Greenhouse Soils and Water. (Unpublished study received Apr 12, 1971 under 1016-69; CDL:050847-E) 101916 Union Carbide Corp. (1970) Full Reports of Investigations Made with Respect to the Safety of the Pesticide Chemical: Temik 10G. Summary of studies 091000-B through 091000-F. (Unpublished study received May 3, 1972 under 2F1188; CDL:091000-A) 101917 Weil, C. (1971) Miscellaneous Toxicity Studies: Special Report 33-92. (Unpublished study received May 3, 1972 under 2F1188; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, DC; CDL:091000-B) 101918 Weil, C.; Woodside, M.; Bernard, J.; et al. (1970) Temik: Results of Feeding in the Diet of Mice for 7 Days: Special Report 33-59. (Unpublished study received May 3, 1972 under 2F1188; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, DC; CDL:091000-C) 101919 Weil, C.; Woodside, M.; Bernard, J.; et al. (1970) Temik (T), Temik Sulfoxide (TSO), Temik Sulfone (TSO2), 1:1 TSO:TSO2: Results of Feeding in the Diet of Rats for 7 Days: Special Report 33-81. (Unpublished study received May 3, 1972 under 2F1188; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, DC; CDL:091000-D) 101920 Dorough, H. (1970) Effect of Temik on Methyl Parathion Toxicity to Mice: PR-2771. (Unpublished study received May 3, 1972 under 2F1188; prepared by Texas A & M Univ., Texas Agricultural Experiment Station, Dept. of Entomology, submitted by Union Carbide Corp., Washington, DC; CDL:091000-E) 101921 Schlinke, J. (1970) Toxicologic effects of five soil nematocides in chickens. American Journal of Veterinary Research 31(6): 1119-1121. (Also In unpublished submission received May 3, 1972 under 2F1188; submitted by Union Carbide Corp., Washington, DC; CDL:091000-F) Page 115 of 191 ------- 101922 Union Carbide Corp. (1970) Nature of the Residue: Aldicarb. Summary of study 091000-H. (Unpublished study received May 3, 1972 under 2F1188; CDL:091000-G) 101923 Union Carbide Corp. (1971) Magnitude of the Residues: Aldicarb. (Compilation; unpublished study received May 3, 1972 under 2F1188; CDL:091000-I) 101924 Union Carbide Corp. (1971) Determination of Total Toxic Temik Residues in Beef Liver by Gas Chromatograpny. (Unpublished study received May 3, 1972 under 2F1188; CDL:091000-J) 101925 Union Carbide Corp. (1971) Temik 10G Aldicarb Pesticide: Summary of Performance Data- Sugarcane and Sweet Potatoes (Louisiana Only). (Unpublished study received May 3, 1972 under 2F1188; CDL:091000-K) 101926 Union Carbide Corp. (1968) Residue Studies of Temik. (Compilation; unpublished study received Jan 24, 1969 under 9F0798; CDL:091371-A) 101928 Union Carbide Corp. (1968) Residue Studies of Temik in Plants and Animals. Summary of studies 091372-B through 091372-Q. (Unpublished study received Apr 18, 1969 under 9F0798; CDL: 091372-A) 101929 Andrawes, N.; Bagley, W.; Herrett, R. (1968) Metabolism of C14Temik in Cotton Plants under Field Conditions: File No. 10492. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-D) 101930 Andrawes, N.; Bagley, W.; Herrett, R. (1968) Degradation of Temik ... in Potato Foliage: File No. 10495. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-F) 101931 Andrawes, N.; Bagley, W.; Herrett, R. (1968) Metabolism and Associated Residues of Temik in Spearment and Lettuce: File No. 10496. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL: 091372-G) 101932 Dorough, H. (1968) Continual Feeding of Radio-labeled Temik to Lactating Dairy Cows. (Unpublished study received Apr 18, 1969 under 9F0798; prepared by Texas A and M Univ., submitted by Union Carbide Corp., New York, NY; CDL:091372-H) 101933 Dorough, H. (1968) Continuous Feeding of Radiolabeled Temik to Laying Hens. (Unpublished study received Apr 18, 1969 under 9F0798; prepared by Texas A and M Univ., submitted by Union Carbide Corp., New York, NY; CDL:091372-I) 101934 Bull, D.; Coppedge, I; Ridgway, R. (19) Fate of Temik in Soil with Special Reference to Chemical Changes, Movement, and Volatilization. (U.S. Agricultural Research Service, Entomology Research Div., Cotton Insects Systemic Chemicals Investigations; unpublished study; CDL:091372-J) 101935 Andrawes, N.; Bagley, W.; Herrett, R. (1968) Temik Metabolism: Fate of C14-Temik in Cultivated Soil: File No. 9218. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-K) 101936 Clarkson, V.; Weiden, M. (1968) Temik Insecticide: The Persistence of Temik in an Agricultural Soil As Indicated by Field and Laboratory Bioassay: File No. 10490. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-L) Page 116 of 191 ------- 101937 Andrawes, N.; Bagley, W.; Herrett, R. (1968) Temik Metabolism: Degradation and Carry- over Properties of... (Temik) in Soil: File No. 10494. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL: 091372-M) 101938 Spurr, H.; Chancey, E. (1968) Temik Insecticide: Interactions between Temik and Microorganisms and Their Importance to Ecological Relationships in Soil: File No. 9208. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-N) 101939 Clarkson, V.; Rowe, B.; Romine, R.; et al. (1968) Temik Insecticide: Field Evaluation of the Persistence and Movement of Temik and Its Carbamate Metabolites in Soil: File No. 10485. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-O) 101940 Clarkson, V.; Rowe, B.; Romine, R. (1968) Temik Insecticide: Field Evaluation of the Persistence of Temik and Its Carbamate Metabolites in Pond Water and Their Effect on Pond Fauna: File No. 10491. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091372-Q) 101941 Union Carbide Corp. (1968) Full Reports of Investigations Made with Respect to the Safety of the Pesticide Chemical: Temik. Summary of studies 005593-C, 005594-B, 091373-B through 091373D, 091373-F through 091373-J, 091373-L, 091373-N through 091373-P, 091373-R through 091373-U, 091373-W, 091373-Y, 091373-Z, 091373-AB, 091373-AC, 126467-A, 126484-D, 126486-A, 126494-A, 131933-A. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-A) 101942 Weil, C.; Condra, N.; White, C.; et al. (1968) Temik 10 G-V (10.3% Granular Formulation of Compound 21149): Acute and 14-day Applications to Rabbits: Special Report 31-137. (Unpublished study received Apr 18, 1969 under 9F0798; prepared by Mellon Institute, Industrial Fellowship, submitted by Union Carbide Corp., New York, NY; CDL:091373-D) 101943 Pozzani, U.; Kinkead, E.; Geary, D.; et al. (1968) Temik 10G and Temik 10G-V: Response of Rats to Saturated Vapors Generated under Simulated Greenhouse Conditions: Special Report 31-173. (Unpublished study received Apr 18, 1969 under 9F0798; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., New York, NY; CDL:091373-F) 101944 Williams, F. (1964) Agricultural Chemicals Compound 21149: Air Sampling While Formulating at Chemical Formulators, Inc. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-G) 101945 Williams, F. (1964) Agricultural Chemicals Compound 21149: Air Sampling during Second Formulations at Chemical Formulators, Inc. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-H) 101946 Williams, F. (1965) Air Sampling Report for Agricultural Chemical Compound 21149. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL: 091373-1) 101947 Peele, R. (1966) Industrial Hygiene--Air Pollution Evaluation of Hazards Associated with the Production of Compound 21149 & Formulation of Temik 10-G Insecticide: Report No. 66- IH-158-I-1. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-J) 101948 Union Carbide Corp. (1966) (Toxicity of Temik to Humans). (Unpublished study received Apr 18, 1969 under 9F0798; CDL:091373-L) Page 117 of 191 ------- 101952 Weil, C.; Andrawes, N.; Bagley, W. (1968) The Toxicity of Temik and Its Metabolites in Mint and Lettuce: Special Report 31-156. (Unpublished study received Apr 18, 1969 under 9F0798; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., New York, NY; CDL:091373-R) 101953 Johnstone, V. (1967) Alleged Temik—Cherry Poisoning Incident, Wenatchee, Washington. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-S) 101954 Union Carbide Corp. (1967) Waddell Case: Toxicity of Temik to Humans. (Compilation; unpublished study received Apr 18, 1969 under 9F0798; CDL:091373-T) 101955 Dernehl, C. (1969) Letter sent to R. Haines dated Jan 9, 1969 Consideration of possible hazard to humans handling cotton plants treated with Temik. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-U) 101956 Back, R. (1968) Temik 10G Granular Pesticide: Field Evaluation of Potential Hazard to Bobwhite Quail. (Unpublished study received Apr 18, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:091373-AB) 101957 Lavoie, K. (1963) Bioassay Record: UC-21149: Peromyscus: Test No. R-14. (U.S. Fish and Wildlife Service, Denver Wildlife Research Center; unpublished study, CDL:091373-AC) 101958 Union Carbide Corp. (1968) Efficacy of Temik 10G on Cotton. (Compilation; unpublished study received on unknown date under 9F0798; CDL:092003-A) 101959 Lund, R.; Haines, R. (1969) Field Evaluation of Temik 10G Aldicarb Pesticide: Potential Hazard to White-tail Deer and Cottontail Rabbits from Simulated Spills. (Unpublished study received Aug 20, 1970 under OF1008; prepared in cooperation with New Jersey, Fish and Game Commission, Black River State Game Field Station, submitted by Union Carbide Corp., Washington, DC; CDL:091748-B) 101960 Clarkson, V.; Haines, R.; Hennsley, W.; et al. (1969) Report on Additional Field Tests with Temik 10G Aldicarb Pesticide on the Potential Hazard to Bobwhite Quail. (Unpublished study received Aug 20, 1970 under OF1008; submitted by Union Carbide Corp., Washington, DC; CDL:091748-C) 101961 Haines, R. (1970) Field Evaluation of Potential Hazard of Temik 10G Aldicarb Pesticide to Valley Quail and Ring-necked Pheasants: Trial I. (Unpublished study received Aug 20, 1970 under OF1008; submitted by Union Carbide Corp., Washington, DC; CDL:091748-D) 101962 Haines, R. (1970) Field Evaluations of Potential Hazard of Temik 10G Aldicarb Pesticide to Valley Quail and Ring-necked Pheasants: Trial II. (Unpublished study received Aug 20, 1970 under OF1008; submitted by Union Carbide Corp., Washington, DC; CDL:091748-E) 101963 Union Carbide Corp. (1970) Discussion of Performance: Temik lOG-Sugar Beets. (Compilation; unpublished study received Aug 20, 1970 under OF1008; CDL:091748-F) 101964 Union Carbide Corp. (1970) Metabolism in Plants: Temik. Summary of studies 091748-H through 091748-J and 091748-L. (Unpublished study received Aug 20, 1970 under OF1008; CDL:091748-G) Page 118 of 191 ------- 101965 Andrawes, N.; Bagley, W.; Herrett, R. (1970) Metabolism of Temik Aldicarb Pesticide ... in Sugar Beets. (Unpublished study received Aug 20, 1970 under OF1008; submitted by Union Carbide Corp., Washington, DC; CDL:091748-I) 101966 Union Carbide Corp. (1970) Magnitude of the Residues: Aldicarb in Sugar Beets. (Compilation; unpublished study received Aug 20, 1970 under OF1008; CDL:091748-K) 101967 Borough, H. (1970) Extraction of Radioactive Residues from Liver of Cow Fed 1.2 ppm Aldicarb-Aldicarb Sulfone-C14 in the Diet for 14 Days. (Unpublished study received Aug 20, 1970 under OF1008; prepared by Univ. of Kentucky, Dept. of Entomology, submitted by Union Carbide Corp., Washington, DC; CDL:091748-L) 101968 Union Carbide Corp. (1969) Soil: Decline of Aldicarb. (Unpublished study received Aug 20, 1970 under OF1008; CDL:091748-M) 101969 Union Carbide Corp. (1967) Continual Feeding of Radio-labeled Temik to Lactating Dairy Cows. (Unpublished study received on unknown date under 7F0573; CDL:092861-A) 101970 Maitlen, I; McDonough, L.; Beroza, M. (1966) Determination of 2-Methyl-2- (methylthio)propionaldehyde O-(methylcarbamoyl) oxime, Its Sulfoxide and Sulfone, by Gas Chromatography. (U.S. Agricultural Research Service, Entomology Research Div.; unpublished study; CDL:092861-B) 101971 Union Carbide Corp. (1967) Efficacy Studies of Temik on Potatoes. (Compilation; unpublished study received Aug 22, 1967 under 7F0573; CDL:092861-E) 101972 Union Carbide Corp. (1966) Study of the Chemical Temik 10G. (Compilation; unpublished study received Feb 23, 1967 under 7F0573; CDL:092861-F) 101973 Romine, R. (1966) Determination of Temik Residues in Potatoes. (Unpublished study received Feb 23, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, WV; CDL:092861-G) 101974 Romine, R. (1966) Determination of Temik Residues in Soil. (Unpublished study received Feb 23, 1967 under 7F0573; submitted by Union Carbide Corp., Charleston, WV; CDL:092861-H) 101975 Union Carbide Corp. (1968) Continual Feeding of Radiolabeled Temik to Chickens. (Unpublished study received on unknown date under 8F0637; CDL:092931-A) 101976 Romine, R. (1967) Determination of Temik Residues in Cottonseed: (A Total Toxic Residues Method). (Unpublished study received on unknown date under 8F0637; submitted by Union Carbide Corp., South Charleston, WV; CDL:092931-C) 101977 Andrawes, N.; Romine, R.; Bagley, W. (1973) Metabolism and residues of Temik aldicarb pesticide in cotton foliage and seed under field conditions. J. Agr. Food Chem. 21(3):379-386. (Also In unpublished submission received Jul 24, 1973 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-A) 101978 Union Carbide Corp. (1968) Determination of Total Toxic Temik Residues in Cottonseed by Gas Chromatography: Basic Cottonseed Method: UC 21149-III-COTS. (Unpublished study received Jan 24, 1969 under 9F0798; CDL:093106-B) 101979 Back, R. (1970) Letter sent to G. Rohwer dated Jul 22, 1970: Temik 10G aldicarb pesticide for use on cotton only. (Unpublished study received on unknown date under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-C) Page 119 of 191 ------- 101980 Dernehl, C. (1970) Letter sent to R. Back dated Jul 13, 1970 Possible Temik poisoning of humans. (Unpublished study received on unknown date under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-D) 101981 Back, R. (1970) Letter sent to H. Hays dated May 12, 1970: Temik 10G aldicarb pesticide for use on cotton only. (Unpublished study received on unknown date under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-E) 101982 Romine, R. (1969) Letter sent to H. Alford dated Nov 12, 1969: Temik 10G, aldicarb pesticide for cotton pest control. (Unpublished study received on unknown date under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-G) 101983 Union Carbide Corp. (1969) Temik Aldicarb Pesticide: The Potential Hazard from Ingestion of Treated Plant Tissue. (Unpublished study received on unknown date under 9F0798; CDL:093106-H) 101984 Back, R. (1969) Letter sent to H. Alford dated Oct 29, 1969: Temik 10G aldicarb pesticide. (Unpublished study received Oct 29, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-1) 101985 Herrett, R. (1967) Letter sent to H. Stansbury dated Feb 7, 1967 Results of studies on the uptake of Temik by spearmint and tendergreen bean. (Unpublished study received Jan 24, 1969 under 9F0798; submitted by Union Carbide Corp., New York, NY; CDL:093106-L) 101986 Union Carbide Corp. (1970) Dermal Toxicity of Formulated Products to Rats: (Four Hour Skin Penetration). (Unpublished study received on unknown date under 9F0798; CDL:093106-N) 101987 Union Carbide Corp. (19) Protocol for Evaluation of Exposure Hazard to Greenhouse Operators Using Temik 10G. (Unpublished study received Jan 24, 1969 under 9F0798; CDL:093106-O) 101988 Union Carbide Corp. (1969) Study of the Chemical Temik. (Compilation; unpublished study received Jul 14, 1969 under 9F0798; CDL:093106-R) 101989 Union Carbide Corp. (1968) Reasonable Grounds in Support of the Petition: Temik 10G. (Unpublished study received Jan 24, 1969 under 9F0798; CDL:093106-V) 101990 Union Carbide Technical Center (19) Determination of Total Toxic Temik Residues in Milk by Gas Chromatography: UC 21149-III-Milk. (Unpublished study received Jun 29, 1970 under OF1008; CDL: 093318-B) 101991 Union Carbide Corp. (1969) Determination of Total Toxic Temik Residues in Beef Liver by Gas Chromatography: UC 21149-IIILiver. (Unpublished study received Jun 29, 1970 under OF1008;CDL:093318-C) 101992 Union Carbide Technical Center (19) Determination of Total Toxic Temik Residues in Sugar Beet Roots by Gas Chromatography: UC 21149-III-SBR. (Unpublished study received Jun 29, 1970 under OF1008; CDL:093318-D) 101993 Union Carbide Corp. (1969) Determination of the Total Toxic Temik Residue in Sugar Beet Tops: UC 21149-III-SBT. (Unpublished study received Jun 29, 1970 under OF1008; CDL:093318-E) Page 120 of 191 ------- 101994 Union Carbide Corp. (1970) Reasonable Grounds in Support of the Petition: Temik 10G. (Unpublished study received Jun 29, 1970 under OF1008; CDL:093318-F) 101995 Union Carbide Corp. (1972) Response to EPA Comments on Pesticide Petition 2F1188: Temik 10G. (Unpublished study received Aug 6, 1971 under 2F1188; CDL:093511-A) 101996 Andrawes, N.; Bagley, W.; Herrett, R. (1971) Metabolism of... (Temik aldicarb pesticide) in potato plants. J. Agr. Food Chem. 19(4):731-737. (Also In unpublished submission received Aug 6, 1971 under 2F1188; submitted by Union Carbide Corp., Washington, DC; CDL:093511-B) 101997 Union Carbide Corp. (1971) Determination of Total Toxic Aldicarb Residues in Sugarcane Stalk by Gas Chromatography. (Unpublished study received Aug 6, 1971 under 2F1188; CDL:093511-F) 101998 Union Carbide Corp. (1971) Determination of Total Toxic Aldicarb Residues in Sweet Potato Root by Gas Chromatography. (Unpublished study received Aug 6, 1971 under 2F1188; CDL:093511-G) 101999 Union Carbide Corp. (1971) Determination of Total Toxic Residues in Sugarcane Leaves by Gas Chromatography. (Unpublished study received Aug 6, 1971 under 2F1188; CDL:093511- H) 102000 Weil, C. (1974) Summary of Interpretation of Previously Presented Toxicity Data and Safety- factor Calculations for Aldicarb. (Unpublished study received on unknown date under 3F1414; prepared in cooperation with Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Washington, DC; CDL:093775-A) 102001 Meeker, R. (1974) Response to EPA Letter of December 19, 1973 (Items 1,2 and 3) Regarding Pesticide Petition 3F1414 and Subsequent Discussion between EPA and UCC, January 11, 1974. (Unpublished study received on unknown date under 3F1414; submitted by Union Carbide Corp., New York, NY; CDL:093775-D) 102002 Williams, C. (1973) Memorandum of a Telephone Conversation. (Telephone conversation with R. Back; unpublished study received on unknown date under 3F1414; prepared in cooperation with U.S. ABPR, submitted by Union Carbide Corp., Washington, DC; CDL: 093775-F) 102003 Union Carbide Corp. (1976) Efficacy Study of Temik on Various Crops. (Compilation; unpublished study received on unknown date under 3F1414; CDL:093775-G) 102004 Union Carbide Corp. (19) Determination of Total Toxic Aldicarb Residues in Peanuts by Gas Chromatography. (Unpublished study received Jun 25, 1973 under 3F1414; CDL:093775-H) 102005 Union Carbide Corp. (19) Determination of Total Aldicarb Residues in Potato Tubers by Gas Chromatography. (Unpublished study received Jun 25, 1973 under 3F1414; CDL:093775-I) 102006 Union Carbide Corp. (1973) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received Jun 25, 1973 under 3F1414; CDL:093775- J) 102007 Union Carbide Corp. (1973) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Methods Used: Aldicarb. (Compilation; unpublished study received Jun 25, 1973 under 3F1414; CDL:093776-A) Page 121 of 191 ------- 102008 Union Carbide Corp. (1973) Nature of the Residue: Aldicarb. Summary of studies 093511-B, 093776-D through 093776-F. (Unpublished study received Jun 25, 1973 under 3F1414; CDL:093776-B) 102009 Andrawes, N.; Moorefield, H. (1972) The Metabolism and Terminal Residues of Temik Aldicarb Pesticide in Peanut Plants under Field Conditions: Project No. 111A12; File No. 17613. (Unpublished study received Jun 25, 1973 under 3F1414; submitted by Union Carbide Corp., Washington, DC; CDL:093776-D) 102011 Lykins, H. (1969) Temik Insecticide: The Effect of Temperature and pH on the Stability of Temik, Temik Sulfoxide and Temik Sulfone in Water: Project No. 111A13. (Unpublished study received Jun 25, 1973 under 3F1414; submitted by Union Carbide Corp., Washington, DC; CDL:093776-G) 102012 Union Carbide Corp. (1972) Residue Data for Aldicarb on Potatoes and Potato Chips. (Compilation; unpublished study received Jun 25, 1973 under 3F1414; CDL:093777-A) 102013 Union Carbide Corp. (1973) Residue Data for Aldicarb: Peanuts. (Compilation; unpublished study received Jun 25, 1973 under 3F1414; CDL:093777-B) 102014 Union Carbide Corp. (1972) Summary and Discussion of Results of Tests with Temik 10G Aldicarb Pesticide on Potatoes. (Compilation; unpublished study received Jun 25, 1973 under 3F1414; CDL:093779-A) 102015 Hodges, L. (1973) Letter sent to L. Terbush dated Nov 13, 1973: Aldicarb pesticide for use on potatoes and peanuts. (Unpublished study received Nov 13, 1973 under 3F1414; submitted by Union Carbide Corp., Washington, DC; CDL:093781-A) 102016 Reed, J.; Stier, E. (1969) Flavor Evaluation Report on Potatoes Treated with Aldicarb Pesticides. (Unpublished study received Nov 13, 1973 under 3F1414; prepared by Rutgers Univ., submitted by Union Carbide Corp., Washington, DC; CDL:093781-B) 102017 Union Carbide Corp. (1975) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received Oct 1, 1975 under 6G1689; CDL:095060- A) 102018 Union Carbide Corp. (1975) Aldicarb: Residues in Meat, Milk, Soil and Various Crops. (Compilation; unpublished study received Oct 1, 1975 under 6G1689; CDL:095060-B) 102019 Union Carbide Corp. (1975) The Name, Chemical Identity, and Composition of the Pesticide Chemical: Aldicarb. (Unpublished study received May 6, 1977 under 1016-69; CDL:096130- A) 102020 Union Carbide Corp. (1977) Discussion of Temik Performance against Nematode and Insect Pests of Coffee. (Compilation; unpublished study received May 6, 1977 under 1016-69; CDL:096130-B) 102021 Union Carbide Corp. (1976) Reasonable Grounds in Support of the Petition: Temik. (Unpublished study received May 6, 1977 under 1016-69; CDL:096130-C) 102022 Andrawes, N.; Dorough, H.; Lindquist, D. (1967) Degradation and elimination of Temik in rats. Journal of Economic Entomology 60(4):979-987. (Also In unpublished submission received May 6, 1977 under 1016-69; submitted by Union Carbide Co., Arlington, VA; CDL:096131-O) Page 122 of 191 ------- 102023 Knaak, I; Tallant, M.; Sullivan, L. (1966) The metabolism of 2-methyl-2- (methylthio)propionaldehyde O-(methyl-carbamoyl)oxime in the rat. J. Agr. Food Chem. 14(6):573-578. (Also In unpublished submission received May 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096131-P) 102024 Union Carbide Corp. (1977) Residue Studies of Aldicarb on Coffee. (Compilation; unpublished study received May 6, 1977 under 1016-69; CDL:096131-T) 102025 Union Carbide Corp. (1976) Discussion of Performance: Temik Aldicarb Pesticide. (Compilation; unpublished study received Jul 13, 1976 under 1016-69; CDL:096175-A) 102026 Union Carbide Corp. (1976) Nature of the Residue: Aldicarb. (Unpublished study received Aug 9, 1977 under 1016-78; CDL: 096302-B) 102027 Union Carbide Corp. (1976) Magnitude of the Residue: Aldicarb. (Compilation; unpublished study received Aug 9, 1977 under 101678; CDL:096302-U) 102028 Union Carbide Corp. (1977) Reasonable Grounds in Support of the Petition: Temik Aldicarb Pesticide. (Unpublished study received Aug 9, 1977 under 1016-78; CDL:096302-V) 102029 Union Carbide Corp. (1977) Alleged Overexposure Cases Reported from Use of Temik Formulations. (Unpublished study received Aug 9, 1977 under 1016-78; CDL:096302-W) 102031 Union Carbide Corp. (1976) Efficacy of Temik Aldicarb Pesticide on Pecan Aphids. (Compilation; unpublished study received Aug 10, 1977 under 1016-78; CDL:096319-A) 102035 Abdalla, N. (1977) Letter sent to F. Sanders dated Oct 19, 1977 Efficacy of Temik on various crops. (Unpublished study received Oct 26, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096396-A) 102036 Heitmuller, T. (1972) Letter sent to S. Ichikawa dated Jan 7, 1972 Toxicity of Temik to grass shrimp. (U.S. Environmental Protection Agency, Gulf Breeze Laboratory; unpublished study; CDL:096397-B) 102037 Shell Chemical Co. (1971) Toxicity Testing: Temik. (Unpublished study received Oct 26, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096397-C) 102038 Hudson, R.; Tucker, R.; Haegele, M. (1972) Effect of age on sensitivity: Acute oral toxicity of 14 pesticides to mallard ducks of several ages. Toxicology and Applied Pharmacology (22):556561. (Also In unpublished submission received Oct 26, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096397-E) 102047 Union Carbide Corp. (1976) Aldicarb: Residues in Citrus. (Compilation; unpublished study received Jul 12, 1976 under 6F1829; CDL:096526-B) 102048 Lykins, H.; Meeker, R. (1971) Aldicarb Pesticide: Stability of Aldicarb in Water: Project No. 111A13, File No. 16060. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-C) 102049 Payne, L.; Stansbury, H.; Weiden, M. (1966) The synthesis and insecticidal properties of some cholinergic trisubstituted acetaldehyde O-(methylcarbamoyl)oximes. Journal of Agricultural and Food Chemistry 14(4):356-365. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-D) Page 123 of 191 ------- 102050 Quraishi, M. (1972) Edaphic and water relationships of aldicarb and its metabolites. Canadian Entomologist 104(Aug): 1191-1196. (Also In unpublished submission received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-E) 102051 Richey, F.; Moorefield, H. (1972) Temik-Aldicarb Pesticide: Metabolism by Soils: Laboratory Studies: Project No. 111A12, File No. 17507. (Unpublished study received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-H) 102052 Richey, F.; Hartley, W.; Sheets, K. (1977) Laboratory studies on the degradation of (the pesticide) aldicarb in soils. Journal of Agricultural and Food Chemistry 25(1):47-51. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-I) 102053 Romine, R.; Meeker, R. (1973) Accumulation of Aldicarb Residues in Fish Tissue from Chronic Exposure to Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone in Aquaria Water: Project No. 111A13, File No. 19009. (Unpublished study received Dec 6, 1977 under 1016- 69; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-K) 102054 Sheets, K.; Hirsh, D.; Meeker, R. (1976) Temik Aldicarb Pesticide: Metabolism of Aldicarb in Anaerobic Muskingum Silt Loam Soil: Project No. 111A13, File No. 22196. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-M) 102055 Skrentny, R.; Ellis, J. (1970) Control of Aphis fabae on broad beans (Viciafaba) by the systemic action of gamma-BHC, thionazin and aldicarb. Pestic. Sci. l(Mar-Apr):45-48. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-N) 102056 Spengler, H.; Griffith, J.; Tamplin, W. (1968) Temik and Temik Metabolites: Vapor Pressure Data: Project No. 111A12, File No. 10819. (Unpublished study received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-O) 102057 Stephen, J.; Durden, J. (1969) A Study of the Decomposition of Temik, Temik Sulfoxide and Temik Sulfone in Water at 100 (degrees): Project No. 111A28, File No. 11815. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-Q) 102058 Supak, J. (1972) The Volatilization, degradation, adsorption, and desorption characteristics of aldicarb ... in soils and clays. Taken from: Dissertation Abstracts 33(3):982. (Order no. 72-24, 336; also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-R) 102059 Verstraete, W.; Voets, J. (19) Impact in sugarbeet crops of some important pesticide treatment systems on the microbial and enzymatic constitution of the soil. Source unknown p. 1263- 1277. (Also In unpublished submission received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096670-S) 102060 Tobler, E.; Johnson, H. (1970) Temik—Aldicarb Pesticide: Thermal Decomposition and Baseand Acid-hydrolysis of Temik: Project No. 116A16, File No. 14185. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-T) 102061 Woodham, D.; Edwards, R.; Reeves, R.; et al. (1973) Total toxic aldicarb residues in soil, cottonseed, and cotton lint following a soil treatment with the insecticide on the Texas high plains. J. Agr. Food Chem. 21(2):303-307. (Also In unpublished submission received Dec 9, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096670-V) Page 124 of 191 ------- 102062 Khasawinah, A. (1977) Environmental Chemistry of Aldicarb. Summary of studies 091000- H, 091372-C, 091372-E, 091372-O, 091372-Q, 091373-F, 096671-B through 096671-1, 096671-M, 096671-P, 096671-R through 096671-Y. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-A) 102064 Andrawes, N.; Bagley, W.; Herrett, R. (1971) Fate and carryover properties of Temik aldicarb pesticide 2-methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime in soil. Agricultural and Food Chemistry 19(4):727-730. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-C) 102065 Andrawes, N.; Meeker, R. (1976) Hydrolysis of Temik Aldicarb Pesticide in Aqueous Buffer Solutions: Project No. 111A13, File No. 22263. (Unpublished study received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096671-D) 102066 Andrawes, N.; Meeker, R. (1976) Hydrolysis of Aldicarb Sulfoxide in Aqueous Buffer Solutions: Project No. 111A13, File No. 223226. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-E) 102067 Andrawes, N.; Meeker, R. (1976) Photochemical Transformation of Aldicarb: Project No. 111A13, File No. 22335. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-F) 102068 Andrawes, N.; Meeker, R. (1976) Photostability of Aldicarb Sulfoxide: Project No. 111A13, File No. 22325. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-G) 102069 Borash, A.; Kramer, V.; Moorefield, H. (1973) Experiments Designed To Trace Movements of Aldicarb in Soil: Project No. 111B13, File No. 17959. (Unpublished study received Dec 6, 1977 under 101669; submitted by Union Carbide Corp., Arlington, VA; CDL: 096671-H) 102070 Myers, R.; Weil, C; Condra, N.; et al. (1975) Temik 10G BC (Coal); 10G and 15G (Gypsum); 15G (Corn Cob): Comparative Toxicity Studies via Peroral, Dermal, and Inhalation Routes: Special Report 38-141. (Unpublished study received Dec 6, 1977 under 1016-69; prepared by Carnegie-Mellon Univ., Institute of Research, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:096671-M) 102071 Coppedge, I; Bull, D.; Ridgeway, R. (1977) Movement and persistence of aldicarb in certain soils. Archives of Environmental Contamination and Toxicology 5(2):129-141. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-P) 102072 Bartley, W.; Heywood, D. (1965) Metabolism Studies: Hydrolytic Stability of UC 21149: 855-31101-7073. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-R) 102073 Hirsh, D.; Sheets, K.; Holsing, G. (1977) Aldicarb Subsequent Crop Residues: File No. 23520. (Unpublished study received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-S) 102074 Hough, A.; Thomason, I; Farmer, W. (1975) Behavior of aldicarb in soil relative to control of Heterodera schachtii. Journal of Nematology 7(3):214-221. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-T) Page 125 of 191 ------- 102075 Iwata, Y.; Westlake, W.; Barkley, I; et al. (1977) Aldicarb residues in oranges, citrus by- products, orange leaves, and soil after an aldicarb soil-application in an orange grove. J. Agric. Food Chem. 25(4):933-937. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-U) 102076 Jones, A. (1976) Metabolism of aldicarb by five soil fungi. J. Agric. Food Chem. 24(1): 115- 117. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-V) 102077 Kaufman, D. (1970) Pesticide metabolism. Pages 73-86, In Pesticides in the Soil: Ecology, Degradation and Movement: International Symposium on Pesticides in the Soil; Feb 25-27, 1970, East Lansing, MI. S.I.: s.n.. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-W) 102078 Kearby, W.; Ercegovich, C.; Bliss, M. (1970) Residue studies on aldicarb in soil and Scotch pine. Journal of Economic Entomology 63(4): 1317-1318. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-X) 102079 Leistra, M.; Smelt, J.; Lexmond, T. (1976) Conversion and leaching of aldicarb in soil columns. Pestic. Sci. 7:471-482. (Also In unpublished submission received Dec 6, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096671-Y) 102086 Stier, E. (1971) Summary on Sensory Evaluation of Potato Samples. (Unpublished study received Dec 19, 1977 under 1016-69; prepared by Rutgers Univ., Dept. of Food Science, submitted by Union Carbide Corp., Arlington, VA; CDL:096682-A) 102087 Union Carbide Corp. (1976) Sensory Evaluation of Cigarettes Made from Tobacco Treated with Temik Aldicarb Pesticide. (Compilation; unpublished study received Dec 19, 1977 under 1016-69; CDL:096682-C) 102088 Foremost Foods Co. (1977) Difference Testing-Kidney Beans: Control versus Temik Treated: Project No. 1387-RI(2). (Unpublished study received Dec 19, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096682-E) 102089 Foremost Research Center (1977) Difference Testing: Fresh Tomatoes-Control versus Temik Treated; Tomato Juice-Control versus Temik Treated; Tomato Paste-Control Versus Temik Treated: Project No. 1387-RI(1). (Unpublished study received Dec 19, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096682-F) 102090 Brasil, Secretaria da Agricultura (1977) Flavor Test in Coffee Treated with Temik 10G at the Rate of 60 Gr. of Formulation per Mat. (Coordenacao de Assistencia Tecnica Integral, Departamento de Assistencia Supletiva; unpublished study; CDL:096682-G) 102091 Union Carbide Corp. (1978) Efficacy of Temik on oranges. (Unpublished study received Jan 17, 1978 under 1016-69; CDL: 096715-A) 102104 Atkins, E.; Kellum, D.; Atkins, K. (1977) Repellent Additives to Reduce Pesticide Hazards to Honey Bees: Maximizing the Effectiveness of Bees as Pollinators of Agricultural Crops: Project No. 3565-RR (W-139). Final rept. (Unpublished study received Jan 27, 1978 under 10182-17; prepared by Univ. of California-Riverside, Citrus Research Center and Agricultural Experiment Station, Dept. of Entomology, submitted by ICI Americas, Inc., Wilmington, DE; CDL:096765-N) Page 126 of 191 ------- 102113 Union Carbide Corp. (1977) Efficacy Studies of Aldicarb on Oranges. (Compilation; unpublished study received on unknown date under 1016-EX-34; CDL:097217-A) 102114 Union Carbide Corp. (1976) Fate of Aldicarb Residues (ppm) in Oranges under Commercial Processing: Complete Data from 3 FractionationLots: Report No. 1. (Unpublished study received on unknown date under 1016-EX-34; CDL:097217-B) 102115 Johnson, D. (1976) Aldicarb Residues in Valencia Oranges: Report No. 2. (Unpublished study received on unknown date under 1016-EX-34; submitted by Union Carbide Corp., Arlington, VA; CDL:097217-C) 102116 Union Carbide Corp. (1977) Discussion of Performance: Temik. Summary of study 097272- B. (Unpublished study received Aug 14, 1978 under 1016-78; CDL:097272-A) 102117 Union Carbide Corp. (1977) Studies on the Efficacy of Sorghum Nematicides. (Compilation; unpublished study received Aug 14, 1978 under 1016-78; CDL:097272-B) 102118 Union Carbide Corp. (1975) Residues of Aldicarb in Meat, Milk, and Other Subjects. (Unpublished study received Oct 19, 1978 under 1016-EX-51; CDL:097628-B) 102119 Union Carbide Corp. (1978) Magnitude of the Residue: Aldicarb. (Compilation; unpublished study received Oct 19, 1978 under 1016-EX-51; CDL:097628-C) 102120 Union Carbide Corp. (1977) Studies on the Efficacy of Temik on Grapes. (Compilation; unpublished study received Oct 19, 1978 under 1016-EX-51; CDL:097628-D) 102121 Union Carbide Corp. (1978) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used and Environmental Chemistry: Aldicarb. (Compilation; unpublished study received Aug 14, 1978 under 1016-78; CDL:097271-C) 102122 Interregional Research Proj ect No. 4. (1976) Nature of the Residue: (Aldicarb). (Unpublished study received Aug 10, 1977 under 7E1996; CDL:097785-A) 102123 Interregional Research Project No. 4. (1977) (Residue Studies for Aldicarb in or on Pecans). (Compilation; unpublished study received Aug 10, 1977 under 7E1996; CDL:097785-U) 102127 Romanko, R. (1979) Aldicarb Insecticide for Control of Hop Pests. (Unpublished study received Feb 8, 1979 under 38338-EX-4; prepared by Southwest Research & Extension Center, submitted by Univ. of Idaho, Twin Falls, ID; CDL:098220-A) 102128 Union Carbide Agricultural Products Co., Inc. (1977) Nature of the Residue: Aldicarb. (Unpublished study received Apr 27, 1979 under 9F2201; CDL:098223-A) 102129 Union Carbide Agricultural Products Co., Inc. (1978) Residue Data for Aldicarb in Lemons, Limes and Grapefruit. (Unpublished study received Apr 27, 1979 under 9F2201; CDL:098223-B) 102130 Union Carbide Agricultural Products Co., Inc. (1978) Residue Data for Temik in Citrus Juices. (Compilation; unpublished study received Apr 27, 1979 under 9F2201; CDL:098223- C) 102131 Union Carbide Corp. (1970) Case of Tony Huerta, Allegedly Poisoned with Temik. (Compilation; unpublished study received Aug 21, 1970 under 1016-69; CDL:100338-A) Page 127 of 191 ------- 102132 Fink, R.; Beavers, I; Brown, R. (1979) Final Report: Eight-day Dietary LC50~Bobwhite Quail: Technical Grade Aldicarb: Project No. 142-118. (Unpublished study received Dec 12, 1979 under 1016-78; prepared by Wildlife International Ltd., submitted by Union Carbide Corp., Arlington, VA; CDL:099120-B) 102133 Schneider, C. (1979) The Acute Toxicity of Aldicarb Technical to the Rainbow Trout (Salmo gairdneri Richardson): UCES Proj. No. 11504-14-03. (Unpublished study received Dec 12, 1979 under 1016-78; submitted by Union Carbide Corp., Arlington, VA; CDL:099120-C) 102134 Schneider, C. (1979) The Acute Toxicity of Aldicarb Technical to the Bluegill Sunfish (Lepomis macrochirus Rafinesque): UCES Proj. No. 11504-14-04. (Unpublished study received Dec 12, 1979 under 1016-78; submitted by Union Carbide Corp., Arlington, VA; CDL:099120-D) 102135 Union Carbide Corp. (1968) Discussion on Residues of Aldicarb Remaining in Plants and Soil from Treatments of Temik 10G to Ornamental Plants. (Unpublished study received Jun 3, 1969 under 1016-69; CDL:101541-A) 102136 Union Carbide Corp. (19) Mortality of Temik-dosed Mice. (Unpublished study received on unknown date under unknown admin, no.; CDL: 102776-A) 102137 Union Carbide Corp. (1971) Criteria Measured at 6-month Kill, or to Date, 5-26-71, on Two- year Rat Feeding Study. (Unpublished study received Jun 11, 1971 under unknown admin. no.; CDL: 102785-A) 102138 Bartley, W. (1965) Letter sent to R. Haines dated Nov 22, 1965 Summary of work in plant metabolism on Temik. (Unpublished study received Nov 26, 1965 under unknown admin, no.; submitted by Union Carbide Corp., Tarrytown, NY; CDL:123009-A) 102139 Union Carbide Corp. (1964) Summary and Discussion of Results of Residue Analyses of Raw Agricultural Crops Treated with UC 21149, 1963-1964. (Compilation; unpublished study received Feb 1, 1966 under unknown admin, no.; CDL:123032-B) 102140 Union Carbide Corp. (1965) Discussion of Performance Tests: UC 21149. (Compilation; unpublished study received Sep 9, 1965 under unknown admin, no.; CDL:126441-A) 102141 Union Carbide Corp. (1965) Summary and Discussion of Results of Residue Analyses of Raw Agricultural Crops Treated with UC 21149, 1963-1964. (Compilation; unpublished study received Sep 9, 1965 under unknown admin, no.; CDL:126443-B) 102142 Stansbury, H.; Johnson, D. (1964) Stability of... (20047) and ... (21149) in Animal Diets: Status Report: Project No. 143B15. (Unpublished study received Sep 9, 1965 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, VA; CDL: 126443-C) 102143 Weil, C.; DeMary, L.; Soo, V (1971) Comparative Skin Penetration Toxicity of Temik 10GV, Temik 15GV and 5 Other Pesticide Formulations As Marketed: Special Report 34-76. (Unpublished study received on unknown date under unknown admin, no.; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, VA; CDL:126446-A) 102144 Dernehl, C. (1972) Letter sent to R. Back dated Apr 28, 1972 Toxicity of Temik 10G in humans. (Unpublished study received on unknown date under unknown admin, no.; submitted by Union Carbide Corp., Arlington, VA; CDL:126446-B) 102145 Borash, A.; Bryant, H. (1965) Test Report on Union Carbide Agricultural Products: (Toxicity to Goldfish). (Unpublished study received Sep 9, 1965 under 1016-EX-24; CDL:126467-A) Page 128 of 191 ------- 102146 Lovell, C.; Quick, Q. (1967) Temik Insecticide: Determination of Temik by Infrared Spectroscopy: Project No. 111A25, File No. 7135. (Unpublished study received May 8, 1967 under 1016EX-22; submitted by Union Carbide Corp., Arlington, VA; CDL: 126474-A) 102147 McDermott, W.; Quick, Q. (1966) Insecticide Temik: Determination of Acetone in Temik 10G and Ambush 2G: Project No. 299A20, File No. 6549. (Unpublished study received Feb 6, 1967 under 1016EX-22; submitted by Union Carbide Corp., Arlington, VA; CDL: 126474- C) 102148 Union Carbide Corp. (1965) Results of Tests Conducted by and under the Supervision of Federal and State Agencies with UC 21149 Formulations on Ornamental Plant Pest Control-- 1962-1964. (Unpublished study received Sep 9, 1965 under 1016-EX-22; CDL: 126475-A) 102149 Union Carbide Corp. (1965) Summary of Selected Performance of UC 21149 on Various Pests on Cotton and Potatoes~1964-1965. (Unpublished study received Jul 26, 1966 under 1016-EX-24; CDL: 126479-A) 102150 Union Carbide Corp. (1965) Petition Proposing Temporary Tolerance for Residue of UC 21149 on and in Cottonseed and Potatoes. (Unpublished study received Feb 1, 1966 under 1016-EX-24; CDL: 126480-A) 102151 Union Carbide Corp. (1965) Efficacy Studies of Carbamate Insecticides on Cotton. (Compilation; unpublished study received Jul 26, 1966 under 1016-EX-24; CDL:126481-B) 102152 Union Carbide Corp. (1966) Accidental Poisoning Report: Temik 10G. (Unpublished study received Oct 8, 1966 under 1016-EX-24; CDL:126483-A) 102153 Stansbury, H. (1966) Letter sent to G. Downard dated Oct 3, 1966: Temik 10G. (Unpublished study received Oct 8, 1966 under 1016EX-24; submitted by Union Carbide Corp., Arlington, VA; CDL: 126483-B) 102154 Union Carbide Corp. (1965) Efficacy Studies of Insecticides on Various Crops. (Compilation; unpublished study received Sep 9, 1965 under 1016-EX-24; CDL:126484-B) 102155 Ketcham, N. (1966) Analyses of Urine Specimens for Metabolite of UC21149: Project No. 299A20, File No. 5882. (Unpublished study received Jul 26, 1966 under 1016-EX-24; submitted by Union Carbide Corp., Arlington, VA; CDL:126494-A) 102156 Stansbury, H.; Wright, M. (1966) Area Ill-Agricultural Products Insecticide Temik: Standard Samples for Residue Analyses: 855-31106-7965. (Unpublished study received Jul 26, 1966 under 1016-EX-24; submitted by Union Carbide Corp., Arlington, VA; CDL:126494-B) 102157 Romine, R. (1966) Summary and Discussion: Temik. (Unpublished study received Jul 26, 1966 under 1016-EX-24; submitted by Union Carbide Corp., Arlington, VA; CDL:126496-B) 102158 Union Carbide Corp. (1966) Determination of Temik Sulfoxide in Human Urine. (Unpublished study received Jul 26, 1966 under 1016-EX-24; CDL:126496-C) 102159 Anderson, H. (1969) Letter sent to J. Harry dated May 21, 1969: Livestock poisoning involving Temik 10G. (Unpublished study received May 28, 1969 under 1016-EX-30; submitted by Union Carbide Corp., Arlington, VA; CDL: 126507-A) Page 129 of 191 ------- 102160 United States of America Standards Institute (1969) Common Name forthe Pest Control Chemical... Aldicarb. New York, NY: USASI. (USAS K62.77-168; also In unpublished submission received Jul 14, 1969 under 1016-EX-30; submitted by Union Carbide Corp., Arlington, VA; CDL:126507-B) 102161 Union Carbide Corp. (1968) Efficacy Study of Temik onPlants. (Compilation; unpublished study received Mar 11, 1969 under 1016-EX-30; CDL:126507-C) 102162 Union Carbide Corp. (19) Metabolic Pathway of Temik in Animals and Acute Toxicity of Metabolites. (Unpublished study received on unknown date under 1016-EX-24; CDL: 127018- A) 102163 Haines, R. (1968) Temik 10G Experimental Systemic Pesticide: F40977E. (Unpublished study received May 1, 1968 under unknown admin, no.; submitted by Union Carbide Corp., Arlington, VA; CDL:130982-A) 102164 Union Carbide Corp. (1965) Summary and Discussion of Results of Residue Analyses of Raw Agricultural Crops Treated with UC 21149, 1963-1964. (Unpublished study received Sep 8, 1965 under unknown admin, no.; CDL:130984-A) 102165 Union Carbide Corp. (1964) UC 21149 Acaricide/Insecticide/Nematocide: F-40977A. (Unpublished study received Mar 1, 1964 under unknown admin, no.; CDL: 131906-A) 102166 Union Carbide Corp. (1965) UC 21149~Experimental Nematocide/Acaricide/Insecticide: F- 40977B. (Unpublished study received Feb 1, 1965 under unknown admin, no.; CDL: 131907- A) 102167 Union Carbide Corp. (1968) Temik 10G Insecticide: Field Evaluation of Potential Hazard to Bobwhite Quail. (Unpublished study received Dec 5, 1968 under 1016-EX-30; CDL: 131937- A) 102169 Union Carbide Corp. (1970) Handling and Safety Guide for Temik 10G Aldicarb Pesticide. SI: UCC. (Also In unpublished submission received May 18, 1970 under 1016-69; CDL:220187-A) 102170 Union Carbide Corp. (1970) Information for Physicians on Therapy of Poisoning by Temik 10G Aldicarb Pesticide. (Unpublished study received May 18, 1970 under 1016-69; CDL:220187-B) 102171 Union Carbide Corp. (1975) Efficacy of Temik Aldicarb Pesticide. (Compilation; unpublished study received on unknown date under 1016-78; CDL:223960-A) 102172 Union Carbide Corp. (1975) Aldicarb Residues in Potatoes Treated with Temik. (Compilation; unpublished study received on unknown date under 1016-78; CDL:223960-B) 102173 Union Carbide Corp. (1975) Efficacy of Temik Compounds on Oranges, Cotton and Other Crops for Control of Various Pests. (Compilation; unpublished study received Feb 15, 1977 under 1016-69; CDL:228048-A) 102174 Iwata, Y. (19) Residue Study of Aldicarb in New Growth Orange Leaves. (Unpublished study received Feb 15, 1977 under 101669; prepared by Univ. of California-Riverside, Dept. of Entomology, submitted by Union Carbide Corp., Arlington, VA; CDL: 228048-B) 102177 Union Carbide Corp. (1976) Nature of the Residue: Aldicarb. (Unpublished study received Sep 21, 1976 under 1016-69; CDL: 232221-A) Page 130 of 191 ------- 102178 Andrawes, N.; Bagley, W.; Herrett, R. (1970) Metabolism and Associated Residues of Temik (2-Methyl-2-(methylthio)propionaldehyde O-(Methylcarbamoyl)-oxime) in Sugar Beet Plants: Project No. 111B19, File No. 12694. (Unpublished study received Sep 21, 1976 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:232221-K) 102179 Andrawes, N.; Moorefield, H. (1972) Metabolism and Terminal Residues of Temik Aldicarb Pesticide in Flue Cured Tobacco: Project No. 111A12, File No. 17805. (Unpublished study received Sep 21, 1976 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:232221-M) 102180 Khasawinah, A.; Hirsh, D.; Meeker, R. (1976) Temik Aldicarb Pesticide: Metabolism of Aldicarb in Green and Cured Tobacco and Pyrolysis Products in Smoke: Project No. 111A13, File No. 21978. (Unpublished study received Sep 21, 1976 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:232221-N) 102181 Union Carbide Corp. (1976) Magnitude of the Residue: Aldicarb Studies on Tobacco. (Compilation; unpublished study received Sep 21, 1976 under 1016-69; CDL:232221-O) 102188 Supak, J. (1972) The Volatilization, Degradation, Adsorption, and Desorption Characteristics of Aldicarb 2-Methyl-2-(methylthio) Propionaldehyde O-(Methylcarbamoyl) Oxime in Soils and Clays. (Dissertation; unpublished study received Oct 23, 1978 under 1016-78; submitted by Union Carbide Corp., Arlington, VA; CDL: 235942-A) 102189 Union Carbide Agricultural Products Co., Inc. (1979) Alleged Temik Human Over-exposure Cases Reported in the U.S. (November 1976-July 1979). Summary of studies 238958-C through 238958-F. (Unpublished study received Aug 16, 1979 under 264-322; CDL: 238958- A) 102190 Union Carbide Agricultural Products Co., Inc. (1977) Pesticide Incident Investigation Record- -Temik Aldicarb Pesticide. (Compilation; unpublished study received Aug 16, 1979 under 264322; CDL:238958-B) 102191 Union Carbide Agricultural Products Co., Inc. (1978) Pesticide Incident Investigation Record: Temik Aldicarb Pesticide. (Compilation; unpublished study received Aug 16, 1979 under 264322; CDL:238958-C) 102192 Union Carbide Agricultural Products Co., Inc. (1978) Pesticide Incident Investigation Record: Temik Aldicarb Pesticide. (Compilation; unpublished study received Aug 16, 1979 under 264322; CDL:238958-D) 102193 Union Carbide Agricultural Products Co., Inc. (1979) Pesticide Incident Investigation Record: Temik Aldicarb Pesticide. (Compilation; unpublished study received Aug 16, 1979 under 264322; CDL:238958-E) 102194 Union Carbide Agricultural Products Co., Inc. (1979) Pesticide Incident Investigation Record: Temik Aldicarb Pesticide. (Compilation; unpublished study received Aug 16, 1979 under 264322; CDL:238958-F) 102195 Moorefield, H. (1979) Aldicarb Pesticide: Mechanism of Action and Therapy: Studies on Cholinesterase Inhibition by Aldicarb Pesticide. Summary of studies 050847-A, 096131-P, 235615-C, 241454-B through 241454-F, 241454-H, 241454-J through 241454-N and 241454- P through 241454-S. (Unpublished study received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-A) Page 131 of 191 ------- 102196 Weiden, M. (1968) Insecticidal carbamoyloximes. J. Sci. Fd Agric., Suppl. P19-31. (Also In unpublished submission received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-B) 102197 Yu, C.; Kearns, C.; Metcalf, R. (1972) Acetylcholinesterase inhibition by substituted phenyl N-alkyl carbamates. J. Agr. Fd. Chem. 20(3):537-540. (Also In unpublished submission received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-C) 102198 Hastings, F.; Main, A.; Iverson, F. (1970) Carbamylation and affinity constants of some carbamate inhibitors of acetylcholinesterase and their relation to analogous substrate constants. J. Agr. Food Chem. 18(3):497-502. (Also In unpublished submission received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-D) 102199 Reiner, E. (1971) Spontaneous reactivation of phosphorylated and carbamylated cholinesterases. Bull WldHlthOrg. 44:109-112. (Published study; CDL:241454-E) 102200 Reiner, E.; Simeon-Rudolf, V. (1966) The kinetics of inhibition of erythrocyte cholinesterase by monomethylcarbamates. Biochem. J. 98:501-505. (Also In unpublished submission received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-F) 102201 Chin, B.; Sullivan, L. (19) (Temik: Toxicity to Dogs). (Unpublished study received Dec 11, 1979 under 264-322; prepared by Mellon Institute, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-H) 102202 Weil, C. (19) (Toxicity of Aldicarb Pesticides to Rats). (Unpublished study received Dec 11, 1979 under 264-322; prepared by Mellon Institute, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-J) 102203 Johnson, H.; Sullivan, L.; McGee, M. (1968) Temik (UC 21149): Antidotal Therapy in Rats following Administration of Multiple Lethal Doses: Special Report 31-146. (Unpublished study received Dec 11, 1979 under 264-322; prepared by Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-M) 102204 Gordon, J.; Leadbeater, L.; Maidment, M. (1978) The protection of animals against organophosphate poisoning by pretreatment with a carbamate. Toxicology and Applied Pharmacology 43:207-216. (Also In unpublished submission received Dec 11, 1979 under 264-322; submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-P) 102206 Goldberg, M.; Johnson, H. (1962) Pharmacodynamic Effects of Cmpd. 21149. (Unpublished study received Dec 11, 1979 under 264-322; prepared by Mellon Institute, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-R) 102207 Striegel, J.; Condra, N.; Haun, C.; et al. (1962) Pharmacodynamic Effects: (Compound 21149): Report 25-53. (Unpublished study received Dec 11, 1979 under 264-322; prepared by Mellon Institute, submitted by Union Carbide Agricultural Products Co., Inc., Ambler, PA; CDL:241454-S) 104551 Abdalla, N. (1977) Letter sent to F. Sanders dated Dec 5, 1977 Environmental chemistry of Temik. Summary of study 096732-B. (Unpublished study received Jan 25, 1978 under 1016- 79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 096732-A) Page 132 of 191 ------- 104552 Khasawinah, A. (1977) Environmental Chemistry of Aldicarb. Summary of studies 096732-C through 096732-AW. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-B) 104553 Union Carbide Corp. (19) Determination of Total Toxic Temik Residues in Sugar Beet Fractions by Gas Chromatography: UC 21149-III-SBF. (Unpublished study received Jan 25, 1978 under 1016-79; CDL:096732-C) 104555 Andrawes, N.; Bagley, W.; Herrett, R. (1971) Fate and carryover properties of Temik aldicarb pesticide ... in soil. Agricultural and Food Chemistry 19(4):727-730. (Also In unpublished submission received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-E) 104556 Andrawes, N.; Meeker, R. (1976) Hydrolysis of Temik Aldicarb Pesticide in Aqueous Buffer Solutions: File No. 22263. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 096732-F) 104557 Andrawes, N.; Meeker, R. (1976) Hydrolysis of Aldicarb Sulfoxide in Aqueous Buffer Solutions: File No. 22326. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-G) 104558 Clarkson, V.; Rowe, B.; Romine, R.; et al. (1968) Field Evaluation of the Persistence and Movement of Temik and Its Carbamates in Soil: File No. 10485. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-P) 104559 Clarkson, V.; Rowe, B.; Romine, R.; et al. (1968) Field Evaluation of the Persistence of Temik and Its Carbamate Metabolites in Pond Water and Their Effect on Pond Fauna: File No. 10491. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-Q) 104560 Kaufman, D. (19) Pesticide metabolism. Pages 73-86, In Pesticides in the Soil: Ecology, Degradation and Movement. By S.I.: s.n.. (Also In unpublished submission received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-Y) 104561 Lin, S.; Funke, B.; Schulz, J. (1972) Effects of some organophosphate and carbamate insecticides on nitrification and legume growth. Plant and Soil 37(3):489-496. (Also In unpublished submission received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AB) 104562 Lykins, H. (1969) The Effect of Temperature and pH on the Stability of Temik, Temik Sulfoxide and Temik Sulfone in Water. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AC) 104563 Lykins, H.; Meeker, R. (1971) Stability of Aldicarb in Water: File No. 16060. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AD) 104564 Quraishi, M. (1972) Edaphic and water relationships of aldicarb and its metabolites. Canadian Entomologist 104(3): 1191-1196. (Also In unpublished submission received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AF) Page 133 of 191 ------- 104565 Richey, F.; Hartley, W.; Singh, R. (1972) Water Leaching of Aldicarb, Aldicarb Sulfoxide, Aldicarb Sulfone and Internal Standard Chloride Ion in Columns of Four Soil Types: File No. 16669. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 096732-AG) 104566 Richey, F.; Moorefield, H. (1972) Upward Movement of Aldicarb through Soil during Water Evaporation: File No. 17526. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 096732-AH) 104567 Romine, R.; Meeker, R.; Roever, K.; et al. (1972) Leaching of Aldicarb into Sandy Soil with Irrigation of a Temik Treated Sugar Beet Field: File No. 17079. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AK) 104568 Romine, R.; Meeker, R.; Gibson, C.; etal. (1973) Accumulation of Aldicarb Residues in Fish Tissue from Chronic Exposure to Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone in Aquaria Water: File No. 19009. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AL) 104569 Romine, R.; Halstead, C.; Gibson, C.; et al. (1968) Leaching Characteristics of Temik 10G in Soils: File No. 10902. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 096732-AN) 104570 Sheets, K.; Hirsh, D.; Meeker, R. (1976) Metabolism of Aldicarb in Anaerobic Muskingum Silt Loam Soil: File No. 22196. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AO) 104571 Skrentny, R.; Ellis, J. (1970) Control of Aphis fabae on broad beans ... by the systemic action of gamma-BHC, thionazinand aldicarb. Pestic. Sci. 1 (Mar/Apr):45-48. (Also In unpublished submission received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AP) 104572 Tobler, E.; Johnson, H. (1970) Thermal Decomposition and Baseand Acid-hydrolysis of Temik: File No. 14185. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-AV) 105062 Hansen, J.; Spiegel, M. (1980) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide, and Aldicarb Sulfone. (Unpublished study received Jun 15, 1982 under 264-318; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:247685-A) 107125 Flanagin, R. (1977) Third Quarterly Report on Temik 15G. (Unpublished study received on unknown date under 1016-EX-34; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:237152-A) 107395 Vilkas, A. (1977) The Acute Toxicity of Aldicarb Technical to the Water Flea ...: UCES Proj. #11504-14-01. (Unpublished study received Dec 19, 1977 under 1016-69; submitted by Union Carbide Corp., Arlington, VA; CDL:096683-A) 107397 Union Carbide Corp. (1976) Nature of the Residue: Aldicarb. (Unpublished study received Aug 14, 1978 under 1016-78; CDL: 097271-B) 107398 Fink, R.; Beavers, J.; Brown, R. (1979) Final Report: Acute Oral LD50~Mallard Duck: Technical Grade Aldicarb: Project No. 142119. (Unpublished study received Dec 12, 1979 under 1016-78; prepared by Wildlife International, Ltd., submitted by Union Carbide Corp., Arlington, VA; CDL:099120-A) Page 134 of 191 ------- 107399 Hall, K.; Le-minh, N. (1976) Shelf-stability of 2 Lb/US Gal Permethrin EC: Report Series TMU0191/76A. (Unpublished study received Dec 2, 1976 under 10182-EX-3; submitted by ICI Americas, Inc., Wilmington, DE; CDL:229013-B) 110506 Union Carbide Agricultural Products Co., Inc. (1982) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used: Aldicarb. (Compilation; unpublished study received May 4, 1982 under 2F2679; CDL: 070835-A) 110512 Union Carbide Agricultural Products Co. (1981) (Temik Efficacy Support Data and Residue Documentation for Use in Soybean Protection from Nematodes). (Compilation; unpublished study received Apr 19, 1982 under IL 82/4; CDL:247347-A) 111923 Union Carbide Corp. (1976) Nature of the Residue: Aldicarb. (Unpublished study received May 6, 1977 under 1016-69; CDL: 096131-A) 114335 Coate, W.; Mense, M.; Hardy, R.; etal. (1982) Subacute Inhalation Toxicity Study of a Pesticide Residue in Dogs: T3,T6, and to Type Cigarettes: Project No. 400-636. Final rept. (Unpublished study received Sep 3, 1982 under 264-330; prepared by Hazleton Laboratories America, Inc., submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL: 248307-A) 115237 Mayberry, R.; Savage, J. (1978) Mutagenic activity of several pesticides using the salmonella test and saccharomyces D3 system. Taken from: Am. Soc. Microbiol, Abstracts on the Annual Meeting. S.I.: s.n.. (Abstract H 126; p. 125; also In unpublished submission received Oct 1, 1982 under 432-482; submitted by Penick Corp., Lyndhurst, NJ; CDL:248482-B) 115301 Hill, E.; Camardese, M. (1981) Subacute toxicity testing with young birds: Response in relation to age and interest variability of LC50 estimates. Avian and Mammalian Wildlife Toxicology 2:41-65. (Also In unpublished submission received Oct 7, 1982 under 201-142; submitted by Shell Chemical Co., Washington, DC; CDL:248514-U) 115963 Hartley, W.; Heywood, D. (1965) Insecticide 21149: Metabolism Studies, Hydrolytic Stability of UC 21149: UCC Status Report 855-31101-7073. (Unpublished study received Jan 25, 1978 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:096732-T) 117840 Johansen, C.; Eves, J. (1967) Bee Research Investigations, 1967. (Unpublished study received Oct 13, 1969 under OF0897; prepared by Washington State Univ., submitted by Fisons Corp., Wilmington, MA; CDL:091551-H) 122315 Fisons, Inc. (1977) Bendiocarb: Occupational Safety Information. (Unpublished study received Sep 9, 1977 under unknown admin, no.; CDL:231544-B) 124047 Union Carbide Corp. (1975) Effectiveness Data: Temik. (Compilation; unpublished study received Oct 1, 1975 under 6G1689; CDL:095061-A) 126065 Wilkinson, C.; Babish, J.; Lemley, A.; et al. (1983) A Toxicological Evaluation of Aldicarb and Its Metabolites in Relation to the Potential Human Health Impact of Aldicarb Residues in Long Island Ground Water. (Unpublished study received Jan 26, 1983 under 264-330; prepared in cooperation with FMC Corp. and others, submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:249416-A) 126500 Union Carbide Corp. (1973) Human Monitoring Study of Field Application of Temik 15G. (Unpublished study received Apr 9, 1974 under 1016-EX-31; CDL:249763-A) Page 135 of 191 ------- 126688 Union Carbide Agricultural Products Co., Inc. (1983) Effectivness Data: Temik. (Compilation; unpublished study received Feb 25, 1983 under 264-330; CDL:071499-A) 127874 Union Carbide Agricultural Products Co., Inc. (1983) Environmental Data: Aldicarb Pesticide: Soil and Water. (Compilation; unpublished study received Apr 15, 1983 under 264- 330; CDL:250012-A) 128132 Weil, C.; DeMary, L.; Soo, V. (1971) Comparative Skin Penetration Toxicity of Temik 10GV, Temik 15GV and 5 Other Pesticide Formulations as Marketed: Special Report 34-76. (Unpublished study received Oct 27, 1971 under 1016-EX-31; prepared by CarnegieMellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:249766-A) 129300 Union Carbide Agricultural Products Co., Inc. (1983) Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used: (Aldoxycarb in or on Vegetable Crops). (Compilation; unpublished study received May 17, 1983 under 264- 401; CDL:071609-E) 129660 Union Carbide Agricultural Products Co., Inc. (1983) Environmental Effects of Temik and Aldicarb. (Compilation; unpublished study received Aug 2, 1983 under 264-330; CDL:250888-A) 129661 Oshima, R.; Torres, G.; Nelson, S.; et al. (1980) Monitoring Selected Ground Water Basins for the Presence of Aldicarb: A Cooperative California Interagency Study. (Unpublished study received Aug 2, 1983 under 264-330; prepared by California Dept. of Food and Agriculture and Others, submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:250888-B) 129662 Hansen, I; Spiegel, M. (1980) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide, and Aldicarb Sulfone. (Unpublished study received Aug 2, 1983 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:250888-C) 131661 Schardein, I; Leng, J. (1983) Teratology Study in Rabbits: Aldicarb: 369-107. (Unpublished study received Oct 18, 1983 under 264-330; prepared by International Research and Development Corp., submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251510-A) 132500 Jones, R. (1982) Letter sent to J. Lovell dated Nov 16, 1982: Data on movement of aldicarb in soil-impact of irrigation. (Unpublished study received Nov 18, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:248850-A) 132501 Hansen, J.; Spiegel, M. (19) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone. (Unpublished study received Nov 18, 1982 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:248851-A) 132647 Weil, C. (1971) Miscellaneous Toxicity Studies: (Sevin and Other Compounds on Rats): Special Report 34-71. (Unpublished study received Nov 3, 1983 under 264-324; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251719-G) 132668 Schardein, J.; Leng, J.; Aldridge, D.; et al. (1983) Teratology Study in Rabbits: Aldicarb: 369- 107. (Unpublished study received Oct 19, 1983 under 264-330; prepared by International Research and Development Corp., submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251731-A) Page 136 of 191 ------- 132989 Ashton, A.; Jackson, W. (1983) Letter sent to Union Carbide dated Nov 18, 1983: Temik field trial (Michigan): Effects on wildlife. (Unpublished study received Dec 13, 1983 under 264- 330; prepared by Bowling Green State Univ., submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251947-A) 133377 Enfield, C.; Carsel, R.; Cohen, S.; et al. (1980) Methods of Approximating Transport of Organic Pollutants to Groundwater. (Unpublished study received Dec 12, 1983 under 100- 617; prepared by U.S. Environmental Protection Agency, Office of Research and Development, Robert S. Kerr Environmental Research Laboratory, submitted by Ciba-Geigy Corp., Greensboro, NC; CDL: 072211-N) 133485 Hansen, I; Jones, R. (1983) Tile-drained Corn: 1983 Studies Conducted in Michigan and Indiana. (Unpublished study received Dec 13, 1983 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251946-A) 133499 Hansen, J.; Jones, R. (1983) Temik and Standak Tobacco Field Studies: 0352G. (Unpublished study received Dec 13, 1983 under 264318; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:251971-A) 134490 Hays, H.W.; Drill, V.A.; Friess, S.L.; et al. (1980) TemikA(R)I Aldicarb Pesticide Review of Toxicological Data and Determination of Acceptable Daily Intake. (Unpublished study received Sep 26, 1980 under unknown admin, no.; prepared by Drill, Friess, Hays, Loomis and Shaffer, Inc. and Johns Hopkins Univ., submitted by Union Carbide Agricultural Products Co., Inc., Wilmington, Del.; CDL:243334-A) 135030 Union Carbide Agricultural Products Co., Inc. (1976) The Name, Chemical Identity and Composition of the Pesticide Chemical: Aldicarb in Dry Beans and Soybeans. (Compilation; unpublished study received Aug 10, 1976 under 6F1849; CDL:096405-A) 135031 Union Carbide Agricultural Products Co., Inc. (1976) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used: Aldicarb in Dry Beans and Soybeans. (Compilation; unpublished study received Aug 10, 1976 under 6F1849; CDL:096405-B) 135437 Romine, R. (1979) Letter sent to J. Lovelli; P. Schroeder dated Jul 11, 1979 Methodology for determination of residues: Standak. (Unpublished study received Jul 18, 1979 under 1016-79; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL: 098391-C) 135901 Union Carbide Corp. (1970) Efficacy of Temik 10G Pesticide. (Compilation; unpublished study received Dec 16, 1970 under 1016-69; CDL:005150-A) 135902 Haines, R. (1972) Letter sent to J. Touhey dated Mar 4, 1972: Temik 10G aldicarb pesticide: Amend to combine cotton and sugar beet directions for use. (Unpublished study received Mar 3, 1972 under 1016-69; submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:005152-A) 136597 Carpenter, C.; Condra, N.; Humes, C.; et al. (1966) Temik 10G (10.5% Granular Formulation of Compound 21149): 15-Day Dermal Applications to Rabbits: Report 29-80. (Unpublished study received Oct 8, 1966 under 1016-69; prepared by Mellon Institute, submitted by Union Carbide Corp., Research Triangle Park, NC; CDL:005580-A) 137875 Union Carbide Agricultural Products Co., Inc. (1980) Residue: Aldicarb in Water. (Compilation; unpublished study received Apr 13, 1984 under 264-330; CDL:252965-A) Page 137 of 191 ------- 137876 Hansen, I; Romine, R.; Jones, R. (1984) Long-term Hydrolysis Studies of Aldicarb Sulfoxide and Aldicarb Sulfone. (Unpublished study received Apr 13, 1984 under 264-330; submitted by Union Carbide Agricultural Products Co., Inc., Research Triangle Park, NC; CDL:252966- A) 138037 Union Carbide Corporation (1964) UC 21149-Experimental Nematocide/ Acaricide/Insecticide: F-40977B. (Unpublished study received Jul 26, 1966 under 6G0473; CDL:090526-A) 139863 Clarkson, V.A.; Hensley, W.H. (1968) Temik Insecticide: Toxicity of Temik, Temik Sulfoxide, and Temik Sulfone Bluegill Sunfish. Project No. 111B32. (Unpublished study received Jan 18, 1977 under 1016-EX-37; submitted by Union Carbide Corp., Arlington, Va.; CDL:238153-C) 139865 Kinkead, E.R.; Chin, B.H.; Weil, C.S.; et al. (1968) Toxicity Studies on Temik: (2-Methyl-2- methylthiopropionaldehyde-N-methylcarbamoyloxime) and Related Carbamates: Special Report 31-48. (Unpublished study received Jan 18, 1977 under 1016-EX-37; prepared by Carnegie-Mellon Univ., Mellon Institute, Chemical Hygiene Fellowship, submitted by Union Carbide Corp., Arlington, Va.; CDL:238153-I) 140001 Romine, R.R. (1976) Letter sent to R.S. Flanagin dated Jan 16, 1976: Citurs fractionation. (Unpublished study received Oct 10, 1975 under 6G1689; submitted by Union Carbide Corp., Washington, D.C.; CDL:096440-A) 140367 Back, R.C. (1970) Letter sent to Harold G. Afford dated Mar 2, 1970: Temik 10G aldicarb pesticide-Third and final periodic report. (Unpublished study received Mar 3, 1970 under 1016-EX30; submitted by Union Carbide Corp., Arlington, Va.; CDL: 126506-A) 140487 Interregional Research Project No. 4 (1977) The Results of Tests on the Amount of Residue Remaining, Including a Description of the Analytical Method Used: Aldicarb in Pecans. (Compilation; unpublished study received Aug 10, 1977 under 7E1996; CDL: 097371-A) 142079 Cimino, M.; Galloway, S.; Ivett, J. (1984) Mutagenicity Evaluation of Aldicarb Technical 93.47% in the Mouse bone marrow cytogentic Assay: Final Report: Project No. 22202. Unpublished study prepared by Litton Bionetics, Inc. 21 p. 142080 Sansebastian, J. (1984) CHO Metaphase Analysis In Vitro Chromosome Aberration Analysis in Chinese Hamster ovary cells: Aldoxycarb Technical: Study No. PH 320-UC-005-83. Unpublished study prepared by Pharmakon Research International, Inc. 33 p. 142081 Godek, E. (1984) Rat Hepatocyte Primary Culture/DNA Repair Test: Aldicarb Technical: Study No. PH 31 l-UC-005-83. Unpublished study prepared by Pharmakon Research International, Inc. 48 p. 142082 Dejonckheere, W. (19) Leaching in Soil and Uptake Bij Sugarbeets of Aldicarb and Thiofanox. Unpublished study prepared by state Uni. Of Gent (Belgium). 25 p. 142083 Hirsh, D.; Sheets, K. (1977) Aldicarb Subsequent Crop Residues: Project No. 812C20. Unpublished study prepared by Union Carbide Corp. 12 p. 142084 Hansen, J.; Jones, R. (1984) Monitoring of Aldicarb and Aldoxycarb Residues on North Carolina and Virginia Tobacco Fields: VO352g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 23 p. Page 138 of 191 ------- 142085 Hansen, I; Jones, R. (1984) Monitoring of Aldicarb Residues in Michigan and Indiana Tile- drained corn Fields: 0332g/015g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 19 p. 142086 Hansen, I; Jones, R. (1984) Degradation and movement of Aldicarb and Aldoxycarb Residues in Arizona cotton: V4639. Unpublished study prepared by Union Carbide Agricultural Products Co. 17 p. 142088 Romine, R.; Hansen, J.; Jones, R. (1984) Aldicarb Oxidation Mechanism Studies: 0596g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 13 p. 142089 Romine, R.; Hansen, J.; Jones, R. (1984) Aldicarb Sulfoxide and Aldicarb Sulfone Groundwater Degradation Mechanism Studies: V4654. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. lip. 142090 Bussain, R. (1984) (Temik Residues in Soil). Unpublished study prepared by Union Carbide Agr. Prod. Co., Inc. 24 p. 142091 Union Carbide Agricultural Products Co., Inc. (1984) (Temik Residues in Water). Unpublished study. 41 p. 142092 Jones, R.; Rourke, R.; Hansen, J. (1984) Effect of Application Methods on Movement and Degradation of Aldicarb Residues in Maine Potato Fields: 0436g. Unpublished study. 28 p. 142093 Hansen, J.; Jones, R. (1984) Degradation And Transport of Aldoxycarb Residues in Southern Florida: V4637. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 14 p. 142094 Union Carbide Agricultural Products Co., Inc. (1984) (Temik Residues in Soil): 0400g. Unpublished compilation. 10 p. 142095 Poter, K.; Lemley, A.; Hughes, H.; et al. (1984) Developing Information. On Aldicarb Levels in Long Island Groundwater: 0483g. Unpublished study prepared by Cornell University and Union Carbide Agricultural Products Co., Inc. 40 p. 142096 Hughes, H.; Trautmann, N.; Porter, K. (1984) Tracking Aldicarb Residues in Long Island Ground Water: Interim Results. Unpublished study prepared by Cornell University. 32 p. 144970 Jackson, W. (1984) Letter sent to T. DeWitt dated June 21, 1984: [A Field study to evaluate the hazard to birds in Corn Fields treated with Temik. 6 p. 144971 Supak, J.; Swoboda, A.; Dixon, J. (1977) Volatilization and Degration Losses of Aldicarb From Soil. J. Environ. Qual. 6(4):413417. 145704 Union Carbide Corporation (1979)[Efficacy Data Temik 10% Granular Aldicarb Pesticide]. Unpublished compilation. 291 p. 147055 Eisler, M. (1966) Adaptation of the Liver to Heptachlor and Its Epoxide. Unpublished study prepared by Velsicol Chemical Corporation. 6 p. 148168 Stankowski, L. (1985) CHO/HGPRT Mammalian Cell Forward Mutation Assay: Aldicarb: PH 314-UC-003-84. Unpublished study prepared by Pharmakon Research International, Inc. 35 p. Page 139 of 191 ------- 148685 Ross, D.; Roberts, N.; Eichler, A. (1977) Temik lOG-Gypsum Formulation (Blue): Wildlife Surveys following Application to Four Sugar Beet and Four Potato Fields: UNC 57/774581. Unpublished study prepared by Huntingdon Research Centre. 255 p. 148686 Ross, D.; Roberts, N.; Cameron, D. (1978) A Comparison of the Palatability to the Ring- necked Pheasant of Three Formulations of Temik 10 G with Other Granular Pesticides: UNC/69C/78938. Unpublished study prepared by Huntingdon Research Centre. 23 p. 148687 Ross, D.; Roberts, N.; Cameron, D. (1978) A Comparison of the Palatability to the Zebra Finch of Two Formulations of Temik: UNC 69 G/78398. Unpublished study prepared by Huntingdon Research Centre. 16 p. 148688 Ross, D.; Roberts, N.; Cameron, D. (1978) A Comparison of the Palatability to the Ring- necked Pheasant of Two Formulations of Temik: UNC 69 G/78399. Unpublished study prepared by Huntingdon Research Centre. 14 p. 148689 Ross, D.; Roberts, N.; Cameron, D. (1979) The Effect of Granule Size on the Toxic Hazard to Passeriformes of Temik 10G: UNC 69B/ 78721. Unpublished study prepared by Huntingdon Research Centre. 16 p. 148690 Stickel, W. (1979) Letter sent to R. Back dated May 29, 1979: [Comments on "Report on palatability studies and trials regarding the acute toxicity of the plant protection products Temik 10 G and Temik 10 GGF (gypsum) with Japanese quails, chickens and sparrows"]. Prepared by the US Fish and Wildlife Service, Patuxent Wildlife Research Center. 3 p. 148691 Tait, F. (1972) Aldicarb: Wild Life Survey 1972. Unpublished study prepared by Duphar- Midox Ltd. 28 p. 148692 United Kingdom, Ministry of Agriculture, Fisheries & Food, Pest Infestation Control Laboratory (1974) A Study of the Effects of Aldicarb or Wildlife. Unpublished study. 65 p. 148693 Brown, P.; Bunyan, P.; Stanley, P.; et al. (1975) Field Surveillance of the Possible Wildlife Hazards Associated with the Use of the Nematicide, Aldicarb: Chemistry Department Report No. 17. Unpublished study prepared by U.K. Ministry of Agriculture, Fisheries and Food, Pest Infestation Control Laboratory. 57 p. 148694 Spencer, D. (1985) A Review of the Research Conducted on the Toxicity and Potential Hazard of Granular Formulations of Aldicarb (Temik) to Bird Life. Unpublished study. 32 p. 148695 Balcomb, R.; Stevens, R.; Bowen, C. (1984) Toxicity of 16 granular insecticides to wild- caught songbirds. Bulletin of Environmental Contamination and Toxicology 33:302-307. 148696 Back, R. (1968) Temik 10G Granular Pesticide: Field Evaluation of Potential Hazard to Bobwhite Quail. Unpublished study prepared by Union Carbide Corp. 15 p. 148697 Benjamini, L. (1981) The efficacy of seed treatment with aldicarb to establish conditioned aversion in birds to sprouting sugar beets. Phytoparasitica 9(l):3-9. 148698 Benjamini, L. (1981) Testing aldicarb as a bird repellent in a sprouting sugar beet field. Phytoparasitica 9(2):89-94. 148699 Clarkson, V.; Rowe, B. (1970) Temik Insecticide: Field Evaluations of the Toxic Hazard of Temik Formulations 10G, 10GV, 10GC and 10GVB4 to Bobwhite Quail: Project No. 111B32: File No. 12676. Unpublished study prepared by Union Carbide Corp. 15 p. Page 140 of 191 ------- 148700 Haines, R. (1970) Temik 10G Granular Pesticide: Field Evaluations of Potential Hazard of Temik 10G Aldicarb Pesticide to Valley Quail and Ring-necked Pheasants in Sugar Beet Plantings: Trial III. Unpublished study prepared by Union Carbide Corp. 8 p. 148701 Haines, R. (1971) Continued Field Evaluations on the Potential Hazard of Temik 10G Aldicarb Pesticide to Valley Quail and Ringnecked Pheasants in a Cotton Planting. Unpublished study prepared by Union Carbide Corp. 7 p. 148702 Haines, R. (1971) Continued Field Evaluations on the Potential Hazards of Temik 10G Aldicarb Pesticide to Bob White Quail in Cotton Plantings. Unpublished study prepared by Union Carbide Corp. 7 p. 148703 Hill, E.; Camardese, M. (1984) Toxicity of anticholinesterase insecticides to birds: Technical grade versus granular formulations. Ecotoxicology and Environmental Safety 8:551-563. 148704 Hilbig, V.; Westphal, D.; Lucas, K.; et al. (1979) Vergleichende Untersuchungen zur Vogeltoxizitaet mit Zwei Granulatformulierungen des Nematizides Temik [Comparative Studies of the Toxicity to Birds of Two Granulated Formulations of Temik Nematocides]: Vetmed-Berichte 2/1979. Unpublished study prepared by Institute of Veterinary Medicine. 24 P- 148705 Lund, R. (1970) Summary of Field Observations: Potential Hazard of Temik 10G Aldicarb Pesticide to Ring-necked Pheasant... from Simulated Spills. Unpublished study prepared by State of New Jersey, Dept. of Conservation and Economic Development, Black River Wildlife Management Area. 2 p. 148706 Medd, R.; Roberts, N. (1972) Palatability and Acceptability of Temik (Corn Cob and Coal Formulations) to the Pheasant and the Pigeon: 5419/72/815. Unpublished study prepared by Huntingdon Research Centre. 31 p. 148707 Medd, R.; Burrows, I.; Roberts, N.; et al. (1972) The Determination of the Single Dose Oral LD50 (24 Hour Value) and Residual Levels of Temik (Coal) in the Pheasant: Amended: 5355/72/751. Unpublished study prepared by Huntingdon Research Centre. 28 p. 148708 Relton, J. (1970) Wild Life Survey: Temik 10G Aldicarb Pesticide on Sugar Beets: Suffolk, England, 1970. Unpublished study, lip. 148709 Ross, D.; Roberts, N.; Cameron, D. (1977) A Comparison of the Acute Oral Toxicity (LD50) of Three Formulations of Temik to the Japanese Quail: UNC 68 W/771042. Unpublished study prepared by Huntingdon Research Centre. 12 p. 148963 Jones, R.; Rourke, R.; Hansen, J. (1985) Effect of Application Methods on Movement and Degradation of Aldicarb Residues in Maine Potato Fields:0830g. Unpublished study prepared by the University of Maine in cooperation with Union Carbide Agricultural Products Co., Inc. 30 p. 148964 Jones, R.; Hansen, J.; Romine, R. (1984) Unsaturated Zone Studies on the Degradation and Movement of Aldicarb and Aldoxycarb Residues: Preliminary Draft:0702g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 69 p. 148965 Jones, R. (1985) Field, Laboratory, and Modeling Studies on the Degradation and Transport of Aldicarb Residue in Soil and Groundwater:0886g. Unpublished study prepared by Union Carbide Agricultural Products Company, Inc. 19 p. Page 141 of 191 ------- 148966 Hansen, I; Romine, R.; Jones, R. (1984) Long-term Hydrolysis Studies of Aldicarb Sulfoxide and Aldicarb Sulfone:Draft: 0167g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 20 p. 148967 Romine, R.; Hansen, J.; Jones, R. (1984) Aldicarb Oxidation Mechanism Studies:Preliminary Draft:0596g. Unpublished study prepared by Union Carbide Agricultural Products Company, Inc. 13 p. 148968 Jones, R.; Hansen, J. (1984) Central California Studies on the Degradation and Movement of Aldicarb Residues:Preliminary Draft: 0729g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 29 p. 148969 Otten, R. (1985) Letter sent to J. Lovell dated April 18, 1985: [Two Week Dose Rangefmding Study in Beagle Dogs with Aldicarb Technical]: Project NO. 400-705. Prepared by Union Carbide Agricultural Products Company, Inc. 9 p. 148970 Wisconsin Association of Manufacturers and Commerce (1985) A Review and Critique of Proposed Groundwater Standards under NR140 as Submitted by the Wisconsin Department of Health and Social Services. Unpublished study. 81 p. 148971 Union Carbide Agricultural Products Company, Inc. (1985) New Registration Data Submitted for Aldicarb Special Review: Residue [Grapefruit]. Unpublished study. 5 p. 149696 Johansen, C.; Mayer, D.; Eves, J.; et al. (1983) Pesticides and bees. Environ. Entomology 12(5):1513-1518. 149699 Hays, H. (1980) Temik Aldicarb Pesticide Review of Toxicological Data and Determination of Acceptable Daily Intake. Unpublished study prepared by Drill, Friess, Hays, Loomis and Shaffer, Inc. 31 p. 150006 Obrist, J. (1984) Comparison of Leaching Behavior of NEMACUR and Temik: Rept. No. 86288. Unpublished study prepared by Mobay Chemical Corp. 5 p. 150181 Union Carbide Agricultural Products Co. (1984) Aldicarb Residues in Forage, Fodder and Grain from Field Corn Treated with Temik 15G. Unpublished study. 31 p. 151820 Union Carbide Agricultural Products Co., Inc. (1985) Aldicarb Residues in Grape Products from Simulated Commercial Wine Processing. Unpublished compilation prepared in cooperation with Morse Laboratories. 22 p. 152095 Union Carbide Agricultural Products Company (1984) The Names, Chemical Identity and Composition of the Pesticide Chemical [Aldicarb and Various Formulations). Unpublished compilation. 79 p. 154893 Myers, W. (1985) The Determination of the Anticipated Residue Values of Aldicarb in Potatoes and Citrus. Unpublished study prepared by Union Carbide Agricultural Products, Inc. 76 p. 156961 Lightfoot, E.; Thorne, P.; Jones, R.; et al. (1986) Laboratory Studies on the Degradation Mechanisms of Aldicarb, Aldicarb Sulfoxide, and Aldicarb Sulfone. Unpublished study prepared by University of Wisconsin and Union Carbide Agricultural Products Co., Inc. 73 p. 156962 Jones, R. (1986) Central California Studies on the Degradation and Movement of Aldicarb Residues: Preliminary Draft. Unpublished study prepared by Union Carbide Agricultural Products Co. 66 p. Page 142 of 191 ------- 156963 Dierberg, F.; Given, C. (1986) Aldicarb studies in ground waters from Florida citrus groves and their relation to ground-water protection. Ground Water 24(1): 16-22. 156964 Porter, K.; Wagenet, R.; Hughes, H.; et al. (1986) Field Research on Aldicarb Management Practices for Upstate New York: [Degradadation of Aldicarb in Soils and Ground Waters-- Field Studies]. Unpublished study prepared by Cornell University and Union Carbide Agricultural Products Co., Inc. 26 p. 156965 Jones, R.; Black, G.; Estes, T.; et al. (1986) Comparison of Computer Model Predictions with Unsaturated Zone Field Data for Aldicarb and Aldoxycarb. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 20 p. 156966 Hegg, R.; Shelley, W.; Jones, R.; et al. (1986) Movement and Degradation of Aldicarb Residues in South Carolina Loamy Sand Soil. Unpublished study prepared by Clemson University and Union Carbide Agricultural Products Co., Inc. 28 p. 156967 Carsel, R.; Parrish, R.; Jones, R.; et al. (1986) Characterizing the Uncertainty of Pesticide Leaching in Agricultural Soils. Unpublished study prepared by US Environmental Protection Agency and Union Carbide Agricultural Products Co., Inc. 49 p. 156968 Jones, R.; Anderson, M.; Hornsby, A.; et al. (1986) Saturated Zone Movement and Degradation of Aldicarb Residues on the Florida Ridge: Preliminary Draft. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc., University of Wisconsin, and University of Florida. 274 p. 157027 Union Carbide Agricultural Products Co. (1986) Advisory: Temik Aldicarb Residues in Potable Water. Unpublished compilation. 94 p. 157987 Thomas, P. (1986) 34 Day Immunotoxicology Study of Aldicarb in Mice: Final Report: IITRI Project L08125. Unpublished study prepared by IIT Research Institute. 339 p. 158262 Crisp, C. (19) The Molecular Design of Systemic Insecticides and Organic Functional Groups in Translocation. Unpublished study prepared by US Dept. of Agriculture, Forest Service, Pacific Southwest Forest and Range Experiment Station, Berkley, CA. 54 p. 158572 Union Carbide Agricultural Products Co. Inc. (1986) Temik Brand Aldicarb Pesticide: [Residue Data and Associated Human Illness]. Unpublished compilation. 96 p. 159569 Lee, R.; Andrawes, N. (1986) Temik Brand Aldicarb Pesticide: Aldicarb Anaerobic Aquatic Degradation: Project No. 803R10. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 26 p. 159570 Andrawes, N.; Lee, R. (1986) Temik Brand Aldicarb Pesticide: Aldicarb Metabolism in Lactating Goats: Project No. 803R10. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 52 p. 159571 Hudson, J.; Romine, R. (1986) Temik Aldicarb Pesticide: Stability of Residues in Frozen Milk and Beef Liver: Project No. 803R12. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 24 p. 159572 Hudson, J.; Romine, R. (1986) Temik Aldicarb Pesticide: Potato Processing Study: Project No. 803R12. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 23 p. 159573 Myers, W. (1986) Letter sent to J. Lovell dated Feb 28, 1986: Temik/soybean processing study. Prepared by Union Carbide Agricultural Products Co., Inc. 5 p. Page 143 of 191 ------- 160086 Back, R. (1985) A Review of Tests for Temik Aldicarb Pesticide Residues in Drinking Water Samples by State, USA and Canada, 19791984. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 9 p. 161701 Union Carbide Agricultural Products Co., Inc. (1984) Experimental Determination of the Degradation Rate of Aldicarb Residues in Long Island Groundwater. Unpublished study. 21 P- 161702 Wyman, I; Jensen, I; Curwen, D.; et al. (1983) Effects of Application Procedures and Irrigation on Degradation and Movement of Aldicarb Residues in Soil. Unpublished study prepared by University of Wisconsin and Union Carbide Agricultural Products Co. Inc. 49 p. 161703 Wyman, I; Curwen, D.; Hansen, J. (1984) Wisconsin Aldicarb and Aldoxycarb: Environmental Monitoring Study. Unpublished study prepared by University of Wisconsin and Union Carbide Agricultural Products Co. 19 p. 161704 Hansen, J.; Jones, R. (1984) Environmental Monitoring Studies on Temik and Standak Tobacco Fields. Unpublished study prepared by Union Carbide Agricultural Products Co. 19 P- 161705 Hansen, J.; Jones, R. (1984) Tile-drained corn 1983 Studies Conducted in Michigan and Indiana. Unpublished study prepared by Union Carbide Agricultural Products Co. 16 p. 161706 Hansen, J.; Jones, R. (1984) Environmental Monitoring Study: Temik and Standak Treated Arizona Cotton. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 17 p. 161707 Waggonet, R.; Porter, K.; Hansen, J.; et al. (1984) Environmental Monitoring Study on Temik Treated New York Potato Fields. Unpublished study prepared by Cornell University and Union Carbide Agricultural Products Co., Inc. 15 p. 161708 Hansen, J.; Jones, R. (1984) Environmental Monitoring Study on Temik Treated Washington Potato Fields. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 13 p. 161709 Union Carbide Agricultural Products Co., Inc. (1984) Fate of Aldicarb in Florida Citrus Soils. Unpublished compilation. 102 p. 161733 Rourke, R.; Hansen, J.; Jones, R. (1984) Environmental Monitoring Study on Temik Treated Maine Potato Fields: Preliminary Draft. Unpublished study prepared by University of Maine and Union Carbide Agricultural Products Co., Inc. 22 p. 161734 Myers, W. (1984) The Results of Tests on the Amount of Residue Remaining, including a Description of the Analytical Method Used: [Aldicarb on Grapes]. Unpublished compilation. 67 p. 162562 Romine, R. (1986) Temik Aldicarb Pesticide Residue in Instant Coffee: Laboratory Project Id.: 803R12. Unpublished study prepared by Union Carbide Agricultural Products Co. and General Foods Corp. 39 p. 162745 McCann, J.; Teeters, W.; Urban, D.; et al. (1981) A short-term dietary toxicity test on small mammals. P. 132-142 of the Second Conference of Avian and Mammalian Wildlife Toxicology; published in American Society for Testing and Materials; 1981. Page 144 of 191 ------- 163274 Union Carbide Agricultural Products Co., Inc. (1986) Temik Aldicarb Pesticide: Rotational Crop Residues: [Summary]. Unpublished study. 39 p. 163275 Maitlen, J. (1982) Persistence of aldicarb in soil relative to the carry-over of residues into crops. J. Agric. Food Chem. 30(3): 589-592. 163276 Union Carbide Agricultural Products Co., Inc. (1986) Temik/Plant Back: Registration Analytical Chemistry Project Outline 1986: [Protocol To Determine Magnitude of Aldicarb Residue in Plantback Crops]: Project No. T86-000-R06. 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Pure and Applied Chemistry 50(5):505-509. 5008717 Dorough, H.W. (1977) Metabolism of Carbamate Insecticides. Research Triangle Park, N.C.: U.S. Environmental Protection Agency, Health Effects Research Laboratory. (EPA report no. EPA-600/1-77-012; available from: NTIS, Springfield, VA; PB-266 223) 5008720 Rodell, S.; Funke, B.R.; Schulz, J.T. (1977) Effects of insecticides on acetylene reduction byAzotobacter vinelandiiand soybean nodules. Plant and Soil 47(2):375-381. 5010222 Worthing, C.R. (1969) Performance of some new insecticides againstMyzus persicae(Sulzer) andTetranychus urticae(Koch) on year-round chrysanthemums. Journal of Horticultural Science 44(3):235-246. 5010817 Coppage, D.L. (1977) Anticholinesterase action of pesticidal carbamates in the central nervous system of poisoned fishes. Pages 93-102,InPhysiological Responses of Marine Biota to Pollutants, Proceedings of a Symposium; Nov, 1975, Milford, Connecticut. Edited by F.J. Vernberg, A. Calabrese, P.P. Thurberg and W.B. Vernberg. New York: Academic Press. 5010818 Harvey, J., Jr. (1975) Metabolism of Aldicarb and methomyl. Pages 389-393,InPesticides: International Union of Pure and Applied Chemistry Third International Congress; Jul 3-9, 1974, Helsinki, Finland. Edited by F. Coulston and F. Korte. Stuttgart, West Germany: George Thieme. (Environmental quality and safety supplement, vol. Ill) 5016283 Lindquist, R.K.; Spadafora, R.R. (1974) Insecticides for greenhouse whitefly control on poinsettias. Pages 5-6,InOhio Florists' Association Bulletin No. 536. Columbus, Ohio: Ohio Florists' Association. Page 145 of 191 ------- 5017001 Gaikawad, S.T.; Samantaray, R.N.; Patnaik, S. (1973) Effect of soil application of biocides on N, P, K availability and C, N transformations in flooded rice soils. Journal of the Indian Society of Soil Science 21(3):263-269. 5018266 Lijinsky, W.; Schmaehl, D. (1978) Carcinogenicity of N-nitroso derivatives of N- methylcarbamate insecticides in rats. Ecotoxicology and Environmental Safety 2(3/4):413- 419. 5018267 Quarles, J.M.; Sega, M.W.; Schenley, C.K.; Lijinsky, W. (1979) Transformation of hamster fetal cells by nitrosated pesticides in a transplacental assay. Cancer Research 39(11):4525- 4533. 40065500 Union Carbide Agricultural Products Co., Inc. (1987) Toxicology Data Submitted in Support of Temik Brand 15 G Aldicarb Pesticide. Compilation of 2 studies. 40065501 Trutter, J. (1987) Aldicarb Foodborne Residue Toxicity Study in Monkeys-Watermelon: Laboratory Project Identification: HLA 400-720. Unpublished study prepared by Hazleton Laboratories America, Inc. 95 p. 40065502 Trutter, J. (1987) Aldicarb Foodborne Residue Toxicity in Monkeys-Bananas: Laboratory Project Identification: HLA 400-720. Unpublished study prepared by Hazleton Laboratories America, Inc. 92 p. 40166600 Union Carbide Agricultural Products Co., Inc. (1987) Submission of Toxicity Data in Support of Registration of Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 study. 40166601 Hamada, N. (1987) Two-week Dose Range-finding Oral Toxicity Study in Beagle Dogs with Aldicarb Technical: Lab Project ID: 400-717. Unpublished study prepared by Hazleton Laboratories America, Inc. 94 p. 40216900 Union Carbide Agricultural Products Co. (1987) Submission of Environmental Fate Data in Support of Temik Brand 15G Aldicarb Pesticide. Transmittal of 3 studies. 40216901 Pacenka, S.; Porter, K.; Jones, R.; et al. (1987) Changing Aldicarb Residue Levels in Soil and Groundwater, Eastern Long Island, New York: 866 ly. Unpublished study prepared by Cornell Univ., Center for Environmental Research. 32 p. 40216902 Jones, R.; Marquardt, T. (1987) Monitoring of Aldicarb Residues in Long Island, New York Potable Wells: 8660y; 1234g. Unpublished study prepared by Union Carbide Agricultural Products Co., Inc. 18 p. 40216903 Jones, R. (1987) The Aldicarb Experience: Results of Monitoring and Research Programs: 1309g; 8662y. Unpublished compilation prepared by Union Carbide Agricultural Products Co., Inc. 48 p. 40232600 Rhone-Poulenc Ag Co. (1987) Submission of Residue Data for Aldicarb in/on Foods in Grocery Markets. Transmittal of 1 study. 40232601 Petersen, B.; Gregorio, C. (1987) Aldicarb Acute Dietary Exposure Analysis: Interim Report. Unpublished study prepared by Technical Assessment Systems, Inc. 429 p. 40390700 Rhone-Poulenc Ag Co. (1987) Submission of Data in Response to Aldicarb Special Review. Transmittal of 1 study. Page 146 of 191 ------- 40390701 Anonymous (1987) Aldicarb National Food Survey (Supplemental Data for Aldicarb Acute Dietary Exposure Analysis Interim Report). Unpublished compilation prepared by Rhone- Poulenc Ag Co. 143 p. 40493300 Rhone-Poulenc Ag Co. (1988) Submission of Environmental Fate Data in Support of Temik Aldicarb. Transmittal of 23 studies. 40493301 Jones, R. (1988) Summary of Aldicarb Research and Monitoring Update. 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(1987) Movement and degradation of aldicarb residues in the saturated zone under citrus groves on the florida ridge. Journal of Contaminant Hydrology 1(1987): 265-285. 40493308 Jones, R. (1987) Central California studies on the degradation and movement of aldicarb residues. Journal of Contaminant Hydrology l(1987):287-298. 40493309 Lightfoot, E.; Thorne, P.; Jones, R.; et al. (1987) Laboratory studies on mechanisms for the degradation of aldicarb, aldicarb sulfoxide and aldicarb sulfone. Environmental Toxicology and Chemistry 6:377-394. 40493310 Jones, R.; Estes, T. (1987) Modeling unsaturated zone movement of aldicarb residues from applications to potatoes in eastern canada. Water Pollution Resource Journal of Canada 22(1):99-106. 40493311 Jones, R. (1987) Aldicarb environmental fate studies conducted in the western united states. P. 105-108 in Fate of Pesticides in Environment by J. Bigger and J. Seiber, Publication 3320. 40493312 Jones, R.; Kirkland, S.; Chancey, E. (1987) Measurement of the environmental fate of aldicarb residues in a nebraska sand hills soil. Applied Agricultural Research 2(3): 177-182. 40493313 Jones, R.; Marquardt, T. (1987) Monitoring of aldicarb residues in long island, new york potable wells. Archives of Environemental Contaminant and Toxicology 16:643-647. 40493314 Wyman, J.; Jones, R.; Medina, J.; et al. (1987) Environmental fate studies of aldicarb and aldoxycarb applications to Wisconsin potatoes. Journal of Contaminant Hydrology 2:61-72. 40493315 Pacenka, S.; Porter, K.; Jones, R.; et al. (1987) Changing aldicarb residue levels in soil and groundwater, eastern Long Island, New York. Journal of Contaminant Hydrology 2:73-91. Page 147 of 191 ------- 40493316 Carsel, R.;Parrish, R.; Jones, R.; etal. (19) Characterizing the Uncertainty of Pesticide Leaching in Agricultural Soils. Unpublished study prepared by Rhone-Poulenc Ag Co. in cooperation with U.S. Environmental Protection Agency. 28 p. 40493317 Carsel, R.; Jones, R.; Hansen, J.; et al. (19) A Simulation Procedure for Groundwater Quality Assessments of Pesticides. Unpublished study prepared by Rhone-Poulenc Ag Co. in cooperation with U.S. Environmental Protection Agency and University of Wisconsin. 28 p. 40493319 Jones, R. (1987) The Aldicarb Experience: 1. Conduct and Impact of Monitoring and Research Programs. Unpublished study prepared by Rhone-Poulenc Ag Co. 24 p. 40493322 Jones, R.; Hornsby, A.; Rao, P. (1987) Degradation and Movement of Aldicarb Residues in Florida Citrus Soils. Unpublished study prepared by Rhone-Poulenc Ag Co. in cooperation with University of Florida. 30 p. 40493323 Carsel, R.; Jones, R. (19) Use of Soil and Meterologic Data Bases for Application of Unsaturated Zone Models for Evaluating Pesticide Transport and Transformation. Unpublished study prepared by Rhone-Poulenc Ag Co. in cooperation with U.S. Environmental Protection Agency. 26 p. 40521600 Rhone-Poulenc Ag Co. (1988) Submission of Residue Summary Data to Support Data Regarding Aldicarb Import Tolerances. Transmittal of 1 study. 40521601 Gunderson, E. (1987) Summary of FY 87 Field Assignment "Pesticides in Imported Fresh Bananas". Unpublished study prepared by Food and Drug Administration. 9 p. 40542500 Rhone-Poulenc Ag Co. (1988) Submission of Data To Support the Registration of Temik (Aldicarb Pesticide): Dissipation Studies. Transmittal of 1 study. 40542501 Bostian, A.; Jones, R. (1988) Temik Brand Aidicarb Pesticide: Limited Drinking Water Well Survey. Unpublished study prepared by Rhone-Poulenc Ag Co. 54 p. 40551800 Rhone-Poulenc AG Co. (1988) Submission of Data in Support of Aldicarb Residue Tolerances. Transmittal of 1 study. 40551801 Petersen, B.; Gregorio, C. (1988) Aldicarb Acute Dietary Exposure Analysis: Final Report. Unpublished compilation prepared by Rhone-Poulenc Ag Co. 1972 p. 40607500 Rhone-Poulenc Ag Co. (1988) Submission of Toxicological Data to Support the Continued Registration of TEMIK Brand 15G Alidicarb Pesticide. Transmittal of 4 studies. 40607501 Rhone-Poulenc Ag Co. (1988) Executive Summary: Application of Temik Brand 15G Aldicarb to Three Major Crops: A Terrestrial Vertebrate Field Study and the Supplemental Report: Temik Brand 15G Aldicarb Pesticide Granule Incorporation Study. Unpublished study. 14 p. 40607502 Fletcher, D. (1988) Application of Temik Brand 15G Aldicarb to Three Major Crops: A Terrestrial Verbebrate Field Study: BLAL Study No. 87 FV 3. Unpublished study prepared by Bio-Life Associates, Ltd. 536 p. 40607503 Rhone-Poulenc Ag Co. (1988) Temik Brand 15G Aldicarb Pesticide Granule Incorporation Study. Unpublished study. 71 p. 40607504 Spencer, D. (1985) A Review of the Research Conducted on the Toxicity and Potential Hazard of Granular Formulations of Aldicarb (TEMIK) to Bird Life. Unpublished study. 34 p. Page 148 of 191 ------- 40636500 Rhone-Poulenc Ag Co. (1988) Submission of Environmental Fate Data to Support the Registration of Temik Brand Aldicarb Pesticide. Transmittal of 2 studies. 40636501 Jones, R. (1988) Progress Report: Measurement of Aldicarb Degradation and Movement for Winter Applications to Grapes. Unpublished study prepared by Rhone-Poulenc Ag Co. 89 p. 40636502 Jones, R. (1988) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. Unpublished study prepared by Rhone-Poulenc Ag Co. 36 p. 40645600 Rhone-Poulenc Ag Co. (1988) Submission Environmental Data in Support of Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 study. 40645601 Rhone-Poulenc Ag Co. (1988) Analyses of Aldicarb Residues Second Quarter Wisconsin Sampling. Unpublished study. 33 p. 40676700 Rhone-Poulenc Ag Co. (1988) Residue Data (Market Basket Survey) submitted To Support Aldicarb Registration. Transmittal of 1 study. 40676701 Peterson, B. (1988) Summary of the Review of the Aldicarb National Food Survey. Unpublished compilation prepared by Technical Assessment Systems, Inc. 51 p. 40677300 US EPA (1981) EPA Compiled Documents Received from the PM for Addition to the Carbaryl Registration Standard. Transmittal of 2 studies. 40677302 Dorough, H. (1973) Metabolism of Carbamate Insecticides: Report No. EPA-650/1-74-002. Unpubllished study prepared by Univ. of Kentucky, Dept. of Entomology. Available from NTIS:PB-231596. 255 p. 40685700 Rhone-Poulenc Ag Co. (1988) Submission of Data To Support the Registration of Temik Brand 15G Aldicarb Pesticide: Residue Data. Transmittal of 1 study. 40685701 Rhone-Poulenc Ag Co. (1988) Analyses of Aldicarb Residues Second Quarter Wisconsin Sampling (Second Batch). Unpublished study. 12 p. 40695900 Rhone-Poulenc Ag Co. (1988) Toxicity Data submitted To Support Aldicarb Registration. Transmittal of 1 study. 40695901 Hamada, N. (1988) One-year Chronic Oral Toxicity Study in Beagle Dogs with Aldicarb Technical: Project ID. 400-706. Unpublished study prepared by Hazleton Laboratories America, Inc. 617 p. 40815800 Rhone-Poulenc Ag Co. (1988) Submission of Environmental Residue Data to Support the Registration of Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 study. 40815801 Rhone-Poulenc Ag Co. (1988) Analyses of Aldicarb Residues: Third Quarter Wisconsin Sampling. Unpublished study. 44 p. 40816600 Rhone-Poulenc Ag Co. (1988) Submission of Data To Support Registration of Temik (Granular Aldicarb): Environmental Fate and Residue Chemistry Data. Transmittal of 12 studies. 40816601 Jones, R. (1988) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. 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(1988) Reflections on Validation and Applications of Unsaturated Zone Models: Aldicarb. Unpublished study prepared by Rhone-Poulenc Ag Co. lip. 40816609 Jones, R.; Gibb, J.; Hank, R. (1988) Review of Unsaturated Zone Laeching Models from a User's Perspective: Aldicarb. Unpublished study prepared by Rhone-Poulenc Ag Co. 14 p. 40816610 Jones, R. (1988) The Aldicarb Experience: 1. Conduct and Impact of Monitoring and Research Programs. Unpublished study prepared by Rhone-Poulenc Ag Co. 23 p. 40816611 Jones, R. (1988) The Aldicarb Experience: 2. Results of Monitoring and Research Programs. Unpublished study prepared by Rhone-Poulenc Ag Co. 50 p. 40816612 Jones, R. (1988) Pesticides in Groundwater: Conduct of Field Research Studies: Aldicarb. Unpublished study prepared by Rhone-Poulenc Ag Co. 35 p. 40884600 Rhone-Poulenc Ag Co. (1988) Submission of Data To Support Registration of Temik: Residue Chemistry Data. Transmittal of 1 study. 40884601 Romine, R. (1988) Temik Brand Aldicarb Pesticide: Aldicarb Residues in Soybean Products: Project ID; 803R10; File No. 40429. Unpublished study prepared by Rhone-Poulenc Ag Co., and Texas A&M University. 74 p. 40925800 U.S. EPA (1984) Standardized Transmittal Document for PDMS Entry of OPP Administrative Records: Aldicarb Registration Standard. Transmittal of 1 document. 40925801 U.S. Environmental Protection Agency (1984) GS140: Aldicarb: Registration Standard. Unpublished study. 1775 p. 40987300 Rhone-Poulenc Ag Co. (1989) Submission of Degradation and Movement Data to Support the Registration for Temik Brand Aldicarb Pesticide. Transmittal of 4 studies. 40987301 Jones, R. (1988) Progress Report: Measurement of Aldicarb Degradation and Movement for Winter Applications to Grapes. Unpublished study prepared by Rhone-Poulenc Ag Co. 109 p. 40987302 Jones, R. (1988) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. 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(1989) Rhone-Poulenc Potable Well Survey Program Conducted During 1987: Additional Site Specific Data. Unpublished compilation. 335 p. 41020302 Jones, R. (1989) Buffer Zone Criteria for United States Soils. Unpublished compilation prepared by Rhone-Poulenc Ag Co. 308 p. 41023000 Rhone-Poulenc Ag Co. (1989) Submission of Residue Data to Support the Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 study. 41023001 Romine, R. (1988) Temik Brand Aldicarb Pesticide...Residues in Rotational Crops: Project No. 803R10: 40455. Unpublished study prepared by Rhone-Poulenc Ag Co. in cooperation with Analytical Development Corp. 278 p. 41054600 Rhone-Poulenc Ag Co. (1989) Submission of Toxicity Data in Support of Temik. Transmittal of 1 study. 41054601 IIT Research Institute (1989) Immunotoxicology Study of Aldicarb in Mice: Phase II: Final Report: IITRI Project No. L08181. Unpublished study. 254 p. 41075500 Rhone-Poulenc Ag Company (1989) Submission of Chemistry Data in Support of Temik Registration Standard. Transmittal of 1 study. 41075501 Helfant, L. (1989) TEMIK brand Aldicarb Pesticide Product Chemistry. Unpublished study prepared by Rhone-Poulenc Ag Company. 15 p. 41088600 Rhone-Poulenc Ag Co. (1989) Submission of Environmental Fate Data to Support the Registration of Temik Brand Aldicarb Pesticide. Transmittal of 2 studies. 41088601 Jones, R. (1989) Progress Report: Measurement of Aldicarb Degradation and Movement for Winter Applications to Grapes. Unpublished study prepared by Rhone-Poulence Ag Co. 27 p. 41088602 Jones, R. (1989) The Aldicarb Experience: 2. Results of Monitoring and Research Programs. Unpublished study prepared by RhonePoulenc Ag Co. 49 p. 41139500 Rhone-Poulenc Ag Co. (1989) Submission of Aldicarb Residue Data. Transmittal of 2 studies. 41139501 Rhone-Poulenc Ag Co. (1989) Analyses of Aldicarb Residues Second Quarter 1989 Wisconsin First Sampling. Unpublished study. 41 p. 4113 9502 Jones, R. (1989) Progess Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. Unpublished study. 54 p. Page 151 of 191 ------- 41189600 Rhone-Poulenc Ag Co. (1989) Submission of Residue Data in Support of Temik brand 15G Aldicarb Pesticide Registration. Transmittal 41189601 Jones, R. (1989) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. Unpublished study prepared by Rhone-Poulenc Ag Company. 55 p. 41216000 Rhone-Poulenc Ag Co. (1989) Submission of Fate Data in Support of Temik Brand 15G Aldicarb Pesticide EPA Reg No. 264-330 and 264426. Transmittal of 1 study. 41216001 Jones, R. (1989) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. Unpublished study prepared by Rhone-Poulenc Ag Co. 19 p. 41255500 U. S. Fish and Wildlife Service (1989) Submission of Toxicity Data. Transmittal of 1 study. 41255501 U. S. Fish and Wildlife Service (1989) Biological Opinion on Selected Pesticides. Unpublished study. 891 p. 41290700 Rhone-Poulenc Ag Co. (1989) Submission of Data on Residues from Potable Wells in Wisconsin. Transmittal of 2 studies. 41290701 Rhone-Poulenc Ag Co. (1989) Analyses of Aldicarb Residues: Third Quarter 1989 Wisconsin Second Sampling. 17 p. 41290702 Jones, R. (1989) Progress Report: Measurement of Aldicarb Degradation and Movement in an Upstate New York Potato Field. Unpublished study prepared by Rhone-Poulenc Ag Co. 59 p. 41363700 Rhone-Poulenc Ag Co. (1990) Submission of Data in Support of Temik 15G and 10G Aldicarb Pesticides Data Call-in: Aldicarb National Food Survey Interim Report. Transmittal of 1 study. 41363701 Romine, R. (1990) First Interim Report for the Aldicarb Data Callin: Temik Residues in National Food Survey Samples. Unpublished compilation prepared by Rhone-Poulenc Ag Co. 29 p. 41377100 U.S. Fish and Wildlife Service (1990) Submission of Biological Opinion Data for Selected Pesticides. Transmittal of 1 study. 41377101 U. S. Fish and Wildlife Service (1989) Biological Opinion Log on Selected Pesticides. Unpublished study. 677 p. 41378500 Rhone-Poulenc Ag Co. (1990) Submission of Environmental Fate Data in Support of Temik Brand Aldicarb Pesticide. Transmittal of 2 studies. 41378501 Rhone-Poulenc Ag Co. (1989) Analyses of Aldicarb Residues Fourth Quarter 1989 Wisconsin First Sampling. Unpublished study. 16 p. 41378502 Rhone-Poulenc Ag Co. (1990) Analyses of Aldicarb Residues Fourth Quarter 1989 Wisconsin Second Sampling. Unpublished study. 12 p. 41392900 Rhone-Poulenc Ag Co. (1990) Submission of Residue Data in Response to the Aldicarb Data Call-in. Transmittal of 1 study. Page 152 of 191 ------- 41392901 Romine, R. (1990) Temik Brand Aldicarb Pesticide Reanalysis of ANFS Samples: Lab Project Number: EC-89-062: 40720. Unpublished study prepared by Rhone-Poulenc Ag Co. 52 p. 41482200 Rhone-Poulenc Ag Co. (1990) Submission of Data To Support Registration of Aldicarb Pesticide (Granular): Residue Chemistry Study. Transmittal of 1 study. 41482201 Jones, R. (1990) Progress Report: Measurement of Aldicarb Degradation and Movement for Winter Application to Grapes. Unpublished study prepared by Phone-Poulenc Ag Co. 129 p. 41509200 Rhone-Poulenc Ag Co. (1990) Submission of Residue Data to Support the Continued Registration of Temik Brand Aldicarb Pesticide. Transmittal of 1 study. 41509201 Rhone-Poulenc Ag Co. (1990) Aldicarb Residue Data from Potato Producing Companies. Unpublished study. 19 p. 41554200 Rhone-Poulenc Ag Co. (1990) Submission of Summary Data in Support of Temik Brand 15G Granular Aldicarb Pesticide. Transmittal of 1 study. 41554201 Florida Department of Agriculture (1990) Aldicarb Citrus Monitoring Data. Unpublished study. 7 p. 41575800 Rhone-Poulenc Ag Co. (1990) Submission of Data To Support Registration of TEMIK Brand 15G Aldicarb Pesticide: Residue Chemistry Study. Transmittal of 1 study. 41575801 Trama, T. (1990) Letter Sent to Letter sent to J. Craig dated July 19, 1990: Temik residue analyses by season and variety. 5 p. 41608700 Rhone-Poulenc Ag Co. (1990) Submission of Toxicity Data in Support of Temik Brand 15G Aldicarb Pesticide Registration. Transmittal of 1 study. 41608701 Hazleton Laboratories. (1990) Aldicarb Interim Cholinesterase Data and Incidence Summary: 5 Week Dog (2 Week Evaluation): Lab Project Number: HLA 656162. Unpublished study. 14 P- 41611100 Rhone-Poulenc Ag Co. (1990) Submission of Toxicity Data in Support of Temik Brand 15G Aldicarb Pesticide Registration. Transmittal of 1 study. 41611101 Hazleton Laboratories. (1990) Aldicarb Interim Cholinesterase Data and Incidence Summary: 5 Week Dog (2 Week Evaluation). Unpublished study. 14 p. 41656800 Rhone-Poulenc Ag Co. (1990) Submission of Toxicity Data to Support the Registration of Temik. Transmittal of 1 Study. 41656801 Charles, J. (1990) Interim Data for Aldicarb 5 Week Dog Cholinesterase Evaluations: Lab Project Number: HLA/656162. Unpublished study prepared by Hazleton Laboratories Inc. 15 P- 41659700 Rhone-Poulenc Ag Co. (1990) Submission of Data To Support the Application for Registration of Temik Brand Aldicarb Pesticide: Groundwater Monitoring Studies. Transmittal of 3 studies. 41659701 Davis, W. (1990) Letter Sent to Letter sent to B. Kapner dated Oct 12, 1990: Ground water monitoring study: TEMIK Brand Aldicarb Pesticide. 3 p. Page 153 of 191 ------- 41659702 Rourke, R.; Jones, R. (1990) Potable Well Monitoring for Aldicarb: Unpublished study prepared by Rhone-Poulenc Ag Co. 18 p. 41659703 Jones, R. (1990) Rhone-Poulenc and Wisconsin Department of Natural Resources Well Monitoring for Aldicarb. Unpublished study prepared by Rhone-Poulenc Ag Co. 27 p. 41661300 Rhone-Poulenc Ag Co. (1990) Submission of Toxicity Data to Support the Registration of Temik. Transmittal of 2 Studies. 41661301 Ivett, J. (1990) Single Acute Exposure Dose Selection Study on Aldicarb: Lab Project Number: 12010/0/459/PO. Unpublished study prepared by Hazleton Laboratories America, Inc. 15 p. 41661302 Ivett, J. (1990) Mutagenicity Test on Aldicarb Technical in the Mouse Bone Marrow Cytogenetic Assay: Lab Project Number: 12010/ 0/451. Unpublished study prepared by Hazleton Laboratories America, Inc. 57 p. 41662500 Rhone-Poulenc AG Co. (1990) Submission of Residue Data to Support the Registration of the Temik Brand Aldicarb. Transmittal of 1 Study. 41662501 Ayers, A.; Jones, R. (1990) Temik Brand Aldicarb Pesticide Limited Aldicarb Drinking Water Well Survey-II. Unpublished study prepared by Rhone-Poulenc AG Co. 335 p. 41668300 Rhone-Poulenc Ag Co. (1990) Submission of Data To Support Registration of Temik Brand Aldicarb Pesticide: Residue Chemistry Study. Transmittal of 1 study. 41668301 Craig, J. (1990) Florida Dept. of Agriculture and Consumer Services Sampling of Citrus for Residues of Aldicarb. Unpublished study prepared by Rhone-Poulenc Ag Co. 7 p. 41708600 Rhone-Poulenc Ag Co. (1990) Submission of Data To Support Temik Brand Aldicarb Registration: Avian Toxicology Response Studies. Transmittal of 4 studies. 41708601 Hobson, J. (1990) Aldicarb: Toxicity to Avian Species: A Position Statement. Unpublished study prepared by Rhone-Poulenc Ag Co. 22 p. 41708602 Hobson, J.; Fish, J. (1990) Aldicarb: Response to the Review by the Ecological Effects Branch of the 1987 Temik Brand Aldicarb Granular Incorporation Study Conducted by J. Fish. Unpublished study prepared by Rhone-Poulenc Ag Co. 16 p. 41708603 Hobson, J. (1990) Aldicarb: Response to the Review by the Ecological Effects Branch of the 1987 Temik Terrestrial Vertebrate Field Study. Unpublished study prepared by Rhone- Poulenc Ag Co. 20 p. 41708604 Kendall, R. (1990) Behavior, Survivability and Biochemical Response of Wild Mourning Doves (Zenaida macroura) Dosed with Aldicarb: Final Research Report Phase I: Lab Project Number: 08035. Unpublished study prepared by ClemsonUniv., Institute of Wildlife and Environ. Toxicology. 29 p. 41739900 Rhone-Poulenc Ag Co. (1990) Submission of Exposure Data In Support of Temik Brand Aldicarb Pesticide Registration. Transmittal of 1 Study. 41739901 Jones, P. (1990) Worker Exposure to Dichoromethane While Simulating The Loading of Temik Brand 15G for Application to Citrus: Lab Project Number: EF-89-27: 91C-4708. Unpublished study prepared by Research Triangle Institute. 206 p. Page 154 of 191 ------- 41749400 Rhone-Poulenc Ag Co. (1990) Submission of Residue Study In Support of Temik Brand Aldicarb Pesticide Registration. Transmittal of 1 Study. 41749401 Chancey, E. (1990) Wisconsin Aldicarb Potable Well Sampling: Unpublished study prepared by Rhone-Poulenc Ag. Co. 27 p. 41844700 Rhone-Poulenc Ag Co. (1991) Submission of Progress Report June 1989 in Response to Data Call-In for Temik Brand Aldicarb Pesticide Registration. Transmittal of 1 Study. 41844701 Harrison, S. (1991) Aldicarb Data Call-In Progress Report. Unpublished study prepared by Rhone-Poulenc Ag. Co. 17 p. 41845700 Mycogen Corp. (1991) Submission of efficacy data to support the registration of M-One Plus Bioinsecticide. Transmittal of 1 study. 41845701 Sorenson, K.; Boylan-Pett, W. (1990) Efficacy data on M-One Plus Bioinsecticide. Unpublished study prepared by North Carolina Ag. Extension, Michigan State Univ. and Univ. of Wisconsin. 104 p. 41865800 Rhone-Poulenc Ag Co. (1991) Submission of Data To Support Registration of Temik Brand Aldicarb: Metabolism Study. Transmittal of 1 study. 41865801 Tyl, R.; Marr, M.; Myers, C. (1991) Preliminary Evaluation of Aldicarb Excretion in the Milk of Lactating CD Rats Exposed to Aldicarb in the Diet: Final Report: Lab Project Number: 60C/4752. Unpublished study prepared by Research Triangle Institute. 130 p. 41919900 Rhone-Poulenc Ag Company (1991) Submission of toxicity data in support of reregistration of aldicarb. Transmittal of 1 study. 41919901 Hamada, N. (1991) Subchronic Toxicity Study in Dogs with Aldicarb Technical: Lab Project Number: 656-162. Unpublished study prepared by Hazleton Washington, Inc. 320 p. 41956100 Rhone-Poulenc (1991) Submission of toxicity data in support of reregistration of Aldicarb technical. Transmittal of 1 study. 41956101 Hamada, N. (1991) Subchronic Toxicity Study in Dogs with Aldicarb Technical: Lab Project Number: 656-162. Unpublished study prepared by Hazleton Washington, Inc. 320 p. 41971800 Rhone-Poulenc Ag Co. (1991) Submission of product benefits data in support of registration of Aldicarb. Transmittal of 1 study. 41971801 Rhone-Poulenc Co. (1991) The Benefits to Agriculture of Pesticide Products Containing Aldicarb. Unpublished study. 282 p. 42002100 Rhone-Poulenc Ag Co. (1991) Submission of Incident Report on Aldicarb for Section 6(a)(2) Requirements. Transmittal of 1 study. 42002101 Davis, W. (1991) Section 6(a)(2) Reporting on Aldicarb AOverexposure Incident. Unpublished study prepared by Rhone-Poulenc Ag Co. 5 p. 42004300 FMC Corp. (1991) Submission of Toxicological data to support the registration of AMMO Insecticides (Cypermethrin). Transmittal of 1 study. 42004301 Palmieri, M. (1991) Aquatic Mesocosm Study of Pesticide Products Containing the Active Ingredient Cypermethrin: Progress Report 13: Lab Project Number A89-2847. Unpublished study prepared by Wildlife International, Ltd. and FMC Corp. 5 p. Page 155 of 191 ------- 42004400 Rhone-Poulenc Ag. Co. (1991) Submission of residue data to support the registration of Aldicarb. Transmittal of 3 studies. 42004401 Hunt, T. (1991) Aldicarb: In-Orchard Variation of the Magnitude and Character of Aldicarb Residues in Oranges: Lab Project Number: EC-91-141. Unpublished study prepared by Rhone-Poulenc Ag. Co. 54 p. 42004402 Hunt, T. (1991) Aldicarb: Comparison of GLC and HPLC Methods for Determining Residues of Aldicarb and It's Metabolites in Potatoes: Lab Project Number: EC-90-094. Unpublished study prepared by Rhone-Poulenc Ag. Co. 55 p. 42004403 Hunt, T. (1991) Aldicarb: Effects of Microwave Cooking on Residues of Aldicarb and It's Metabolites in Potatoes: Lab Project Number EC-90-094. Unpublished study prepared by Rhone-Poulenc Ag. Co. 71 p. 42016900 Rhone-Poulenc Ag Co. (1991) Submission of residue data in support of registration of Temik brand aldicarb pesticide. Transmittal of 1 study. 42016901 Hunt, T. (1991) Aldicarb: In-Orchard Variartion of the Magnitude and Character of Aldicarb Residues in Oranges and Grapefruit and Stability of These Residues in Commercial Storage: Lab Project Number: EC-90-093. Unpublished study prepared by Rhone-Poulenc Ag Co. 95 P- 42017400 Rhone-Poulenc Ag Co. (1991) Submission of environmental fate data in support of registration of Temik. Transmittal of 1 study. 42017401 Stratton, G. (1986) Metabolism of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone in Potato Plants and in Plant Callus Tissue Cultures of Potato Tuber and Citron Fruit. Unpublished study prepared by University of Florida. 280 p. 42040600 Rhone-Poulenc Ag Co. (1991) Submission of residue data to support the registration standard for Aldicarb. Transmittal of 1 study. 42040601 Tew, E. (1991) Aldicarb: Magnitude of the Residues in Bananas Treated with Temik 15G: Lab Project Number: EC-90-123. Unpublished study prepared by Rhone-Poulenc Ag. Co. 62 P- 42073400 Rhone-Poulenc Ag Co. (1991) Submission of Data To Support Section 6(a)(2) FIFRA Requirements: Chronic Toxicity Study of Aldicarb on Rat. Transmittal of 1 study. 42073401 Davis, W. (1991) Letter Sent to S. Haddad dated October 29, 1991: Concerning a chronic rat study being conducted on Aldicarb. Prepared by Rhone-Poulenc Ag Co. 1 p. 42073600 Rhone-Poulenc Ag. Co. (1991) Submission of metabolism data to support the registration standard for Aldicarb in Temik 15G. Transmittal of 1 study. 42073601 Hunt, T. (1991) Determination of Rate of Degradation of Aldicarb Carbamate Residues in Potatoes Stored under Simulated Commercial Conditions: Lab Project Number: EC-89-085: 40986. Unpublished study prepared by Rhone-Poulenc Ag. Company. 39 p. 42121500 Rhone-Poulenc Ag. (1991) Submission of Section 6(a)(2) Data in Response to Request for Additional Factual Information Regarding Temik Brand Aldicarb Pesticide Unreasonable Adverse Effects: Groundwater Monitoring Study. Transmittal of 1 study. Page 156 of 191 ------- 42121501 Chancy, E. (1991) Rhone-Poulenc Analyses of Water Sample from Wisconsin Wells for the Period August to October 1991. Unpublished study prepared Rhone-Poulenc Ag. 21 p. 42148400 Rhone-Poulenc Ag Co. (1991) Submission of Data To Support Temik Brand Aldicarb Pesticide Registration: Additional Factual Toxicology Information Regarding Unreasonable Adverse Effects Under Section 6(a)(2). Transmittal of 1 study. 42148401 Lemen, J. (1991) Two-Generation Reproduction Study in Rats with Aldicarb: Lab Project Number: 656-157. Unpublished study prepared by Hazleton Washington, Inc. 1946 p. 42154300 Rhone-Poulenc Ag Co. (1991) Submission of Data To Support Registration of Temik Brand Aldicarb: Toxicology (Exposure) Study. Transmittal of 1 study. 42154301 Peterson, H.; McPheeters, B.; et al. (1991) Preliminary Results of Rhone-Poulenc's Review of Goldman et al. "Aldicarb Food Poisoning in California 1985-1988: Toxicity Estimates for Humans" 45 Archives of Environmental Health 141 (1990). Unpublished study prepared by Rhone-Poulenc Ag Co. 64 p. 42180600 Rhone-Poulenc Ag. Company (1991) Submission of information in pursuant of Section 6(a)(2) of FIFRA reporting a potential overexposure of a 14 month old girl to a cookie treated with Temik and an unknown pelleted rodenticide. Transmittal of 1 study. 42180601 Davis, W. (1991) Letter Sent to S. Haddad, December 10, 1991: (Letter concerning exposure of a child to Temik and an unknown rodenticide). Prepared by Rhone-Poulenc Ag. Co. 1 p. 42191500 Rhone-Poulenc Ag Co. (1991) Submission of Data To Support Registration of Temik (Aldicarb): Toxicology Study. Transmittal of 1 study. 42191501 Hamada, N.; Thakur, A. (1991) One-Year Chronic Oral Toxicity Study in Dogs with Aldicarb Technical: Addendum to Final Report: Lab Project Number: 400-706. Unpublished study prepared by Hazleton Washington, Inc. 13 p. 42226200 Rhone-Poulenc Ag Co. (1992) Submission of Data To Support Temik Brand 15G (Aldicarb Pesticide) Registration for Label Amendments: Field Crop Accumulation Study. Transmittal of 1 study. 42226201 Hunt, T. (1992) Field Accumulation Study on Rotational Crops Temik/Plant-Back Residue Program: Lab Project Number: EC/R-89-002. Unpublished study prepared by Rhone-Poulenc Ag Co.; Stewart Agricultural Research, Inc.; Chemalysis Lab.; et al. 628 p. 42243300 Rhone-Poulenc Ag Co. (1992) Submission of additional adverse effects data and incident reports concerning Temik (Aldicarb) under FIFRA 6(a)(2) status. Transmittal of 1 study. 42243301 W. Davis (1992) Letter Sent to S. Haddad dated February 19, 1992: Concerning deaths of an ocelot, two oppossums, and four raccoons at Atascosa Wildlife Refuge in Rio Hondo, Texas. Prepared by Rhone-Poulenc Ag. Co. 1 p. 42243400 Rhone-Poulenc Ag Co. (1992) Submission of Data To Support FIFRA 6(A)(2) Requirements for Temik Brand Aldicarb Adverse Effects. Transmittal of 1 study. 42243401 Davis, W. (1992) Letter Sent to S. Haddad dated February 24, 1992: Concerning Florida drinking potable water monitoring aldicarb. Prepared by Rhone-Poulenc Ag Co. 3 p. 42247200 Rhone-Poulenc Ag Co. (1992) Submission of Data To Support Temik Brand Aldicarb Registration: Residue Chemistry Study. Transmittal of 1 study. Page 157 of 191 ------- 42247201 Tew,E. (1992) Determination of Aldicarb Residues in Potatoes Treated with Temik 15G Under Furrow and Under Overhead Irrigation Practices in the Pacific Northwest: Final Report: Lab Project Number: EC-90-115: 41095. Unpublished study prepared by Rhone- Poulenc Ag Co. 132 p. 42275700 Rhone-Poulenc (1992) Submission of toxicity data in support of registration of Temik (Aldicarb). Transmittal of 1 study. 42275701 Lemen, J. (1992) Pilot Reproduction Study in Rats with Aldicarb: Lab Project Number: 656- 156. Unpublished study prepared by HazletonLabs., America, Inc. 425 p. 42293700 Rhone-Poulenc Ag Co. (1992) Submission of residue data in support of the registration of Aldicarb. Transmittal of 1 study. 42293701 Gustafson, D. (1992) Potable Well Water Monitoring for Aldicarb in Wisconsin: Results for all Wells Sampled in 1991: Final Summary Report: Lab Project Number: 41194. Unpublished study prepared by Rhone-Poulenc Ag Co. 62 p. 42305800 Rhone-Poulenc AG Co. (1992) Submission of Data To Support Aldicarb Registration Standard: Residue Chemistry Study. Transmittal of 1 study. 42305801 Romine, R. (1989) Temik Brand Aldicarb Pesticide: Aldicarb Residues in Dried Potato Products: Lab Project Number: 803R10: 40479. Unpublished study prepared by Rhone- Poulenc Ag., Co. 72 p. 42307500 Rhone-Poulenc Ag Co. (1992) Submission of Data To Support FIFRA 6(a)(2) Requirements for Aldicarb: Residue in drinking water. Transmittal of 1 study. 42307501 Davis, W. (1992) Letter Sent to S. Haddad dated April 28, 1992: (Concerning aldicarb, aldicarb sulfoxide and sulfone residues in a drinking water well). Prepared by Rhone-Poulenc Ag Co. 2 p. 42316000 Univ. of Georgia (1992) Submission of an incident report involving Furadan 4-F: Data submitted under FIFRA 6(a)(2). Transmittal of 1 study. 42316001 Smith, K. (1992) Clinical Necropsy report on three red-tailed hawks found near Edgefield, South Carolina. Prepared by Univ. of Ga., College of Veterinary Med. 2 p. 42316100 Univ. of Georgia (1992) Submission of an incident report involving Temik in the wildlife kill of a gray fox. Data submitted under FIFRA 6(a)(2). Transmittal of 1 study. 42316101 Smith, K. (1992) Clinical Necropsy Report on a Gray Fox Found near Edgefield, South Carolina. Unpublished study prepared by Univ. of Georgia, College of Veterinary Med. 2 p. 42316200 Univ. of Georgia (1992) Submission of an incident report involving Temik in a wildlife kill of raccoons. Data submitted under FIFRA 6(a)(2). Transmittal of 1 study. 42316201 Smith, K. (1992) Clinical Necropsy Record on a Raccoon Found near Edgefield, South Carolina. Unpublished study prepared by Univ. of Ga., College of Veterinary Med. 2 p. 42316500 Rhone-Poulenc Ag. Co. (1992) Submission of incident reports under FIFRA 6(a)(2) Status (Adverse effects and incident report) to support the reregistration of Temik (Aldicarb) pesticide. Transmittal of 1 study. 42316501 Davis, W. (1992) Letter Sent to S. Haddad dated May 11, 1992: Death of dogs and cats in two separate incidents related to Temik (Aldicarb). 2 p. Page 158 of 191 ------- 42372300 Rhone-Poulenc Ag Comp. (1992) Submission of Literature Review in Support of Registration for Temik brand Aldicarb. Transmittal of 1 study. 42372301 Cole, P.; Pastides, H.; Rothman, K. (1992) The Epidemiologh of Aldicarb Exposure in Humans: A Critique of the Literature with emphasis on its Application to Risk Assessment: . Unpublished study prepared by Rhone-Poulenc Ag Company. 26 p. 42373000 Rhone-Poulenc Ag Co. (1992) Submission of safety data in support of the registration standard for Aldicarb. Transmittal of 1 study. 42373001 Wyld, P.; Watson, C.; Nimmo, W.; et al. (1992) A Safety and Tolerability Study of Aldicarb at Various Dose Levels in Healthy Male and Female Volunteers: Lab Project Number: 003237. Unpublished study prepared by Inveresk Clinical Research. 372 p. 42436500 Rhone-Poulenc Ag Co. (1992) Submission of residue analytical methods data in support of TEMIK brand Aldicarb pesticide registration. 42436501 VerHey, M. (1992) Testing of Aldicarb, Aldicarb Sulfone and Aldicarb Sulfoxide through Protocol E: Final Report: Lab Project Number: 1181. Unpublished study prepared by Colorado Analytical Research & Development Corp. 35 p. 42436600 Rhone-Poulenc Ag Co. (1992) Supplemental submission of residue data in support of the data call-in for Aldicarb. Transmittal of 6 studies. 42436601 Honeycutt, R.; Andrawes, N. (1992) Summary Report on the Nature of Residues of carbon 14-Aldicarb in Plants: Final Report: Lab Project Number: 92-102. Unpublished study prepared by Rhone-Poulenc Ag Co. 70 p. 42436602 Andrawes, N.; Bagley, W. (1992) Metabolism and Associated Residues of Temik (2-methyl- 2-(methylthio) propionaldehyde O-(methylcarbamoyl)oxime (TEMIK) in Sugar Beet Plants: Lab Project Number: 11 IB 19: 12694. Unpublished study prepared by H.E.R.A.C. 52 p. 42436603 Andrawes, N. (1992) The Metabolism and Terminal Residues of Temik Aldicarb Pesticide in Peanut Plants under Field Conditions: Lab Project Number: 111A12: 17613. Unpublished study prepared by H.E.R.A.C. 47 p. 42436604 Andrawes, N.; Bagley, W. (1992) Degradation of 2-methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime (TEMIK) in Potato Foliage: Reformatted: Lab Project Number: 111B19: 10495. Unpublished study prepared by H.E.R.A.C. 44 p. 42436605 Andrawes, N.; Bagley, W. (1992) Metabolism of 2-methyl-2-(methylthio)propionaldehyde O- (methylcarbamoyl)oxime (TEMIK Aldicarb Pesticide) in Potato Plants: Reformatted. Unpublished study prepared by H.E.R.A.C. 60 p. 42436606 Andrawes, N.; Romine, R.; Bagley, W. (1992) Metabolism and Residues of TEMIK Aldicarb Pesticide in Cotton Foliage and Seed under Field Conditions: Reformatted. Unpublished study prepared by H.E.R.A.C. 82 p. 42446500 Rhone-Poulenc Ag Co. (1992) Submission of toxicity data to support the registration standard for Temik (aldicarb). Transmittal of 1 study. 42446501 Kendall, R. (1992) Behavior, Survivability and Biochemical Response of Wild Northern Bobwhites (Colinus virginianus) Dosed with Temik: Lab Project Number: 08034. Unpublished study prepared by ClemsonUniv., Inst. of Wildlife and Environ. Tox. 34 p. Page 159 of 191 ------- 42456000 Rhone-Poulenc Ag Co. (1992) Submission of fate data in support data in support of FIFRA 6(a)(2) requirements of Temik brand Aldicarb Pesticide. Transmittal of 1 study. 42456001 Davis, W. (1992) Letter Sent to Sepehr Haddad dated August 10, 1992 concerning residues of aldicarb sulfone and aldicarb sulfoxide in two Florida wells. Prepared by Rhone-Poulenc. 2 p. 42456100 Rhone-Poulenc (1992) Submission of fate data in support of FIFRA 6(a)(2) requirements for Temik Brand Aldicarb. Transmittal of 1 study. 42456101 Davis, W. (1992) Letter Sent to Office of Pesticide Programs dated August 28, 1992 concerning Aldicarb in a well in Maine. Prepared by Rhone-Poulenc. 1 p. 42456200 Rhone-Poulenc (1992) Submission of fate data in support of FIFRA 6(a)(2) requirements for Temik brand Aldicarb Pesticide. Transmittal of 1 study. 42456201 Gustafson, D. (1992) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Analyzed 1Q, 1992 (Exclusive of Long Island, NY): Lab Project Number: 41206: EC-92-182. Unpublished study prepared by Rhone-Poulenc Ag Co. 55 p. 42467300 Rhone-Poulenc Ag Co. (1992) Submission of residue chemistry data to support Aldicarb reregistration. Transmittal of 2 studies. 42467301 Tew, E. (1992) Aldicarb: Stability of Residue on Frozen Potato Processed Fractions: Final Report: Lab Project Number: EC-92-201. Unpublished study prepared by Rhone-Poulenc Ag Co. 62 p. 42467302 Tew, E. (1992) Aldicarb: Stability of Residues on Frozen Soybean Processed Fractions: Final Report: Lab Project Number: EC-92-200. Unpublished study prepared by Rhone-Poulenc Ag Co. 54 p. 42487600 Rhone-Poulenc Ag Co. (1992) Submission of residue survey data to support registration of TEMIK products. Transmittal of 1 study. 42487601 Rogers, C. (1992) Aldicarb Survey 1991: Texas. Unpublished study prepared by Texas Water Commission. 9 p. 42498200 Rhone-Poulenc Ag Co. (1992) Submittal of Environmental Fate Data in Support of the Aldicarb Data Call-in. Transmittal of 2 studies. 42498201 Das, Y. (1990) Photodegradation of (S-Methyl-carbon 14) Aldicarb in Aqueous Solution Buffered atpH 5 under Artificial Sunlight: Lab Project Number: 90021. Unpublished study prepared by Innovative Scientific Services, Inc. 91 p. 42498202 Dykes, J. (1990) Soil Adsorption/Desorption with Carbon 14Aldicarb: Lab Project Number: 37352. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 326 p. 42509400 Rhone Poulenc Ag Co. (1992) Submittal of chronic oncogenicity data on Aldicarb in support of FIFRA 6(a)(2). Transmittal of 1 study. 42509401 Davis, W. (1992) Letter Sent to Letter Sent to S. Haddad dated September 29, 1992 Regarding the Temik Brand Aldicarb Pesticide Feeding Study in Rats. Prepared by Rhone Poulenc Ag Co. 2 p. 42515700 Rhone-Poulenc Ag Co. (1992) Submission of TEMIK residue chemistry data under FIFRA 6(a)(2) to support TEMIK products registration. Transmittal of 1 study. Page 160 of 191 ------- 42515701 Davis, W. (1992) Letter sent to S. Haddad dated Oct. 9, 1992: TEMIK brand Aldicard pesticide residues in Florida drinking water wells. Prepared by Rhone-Poulenc Ag Co. 2 p. 42523400 Rhone-Poulenc Ag. Co. (1992) Submission of product chemistry data to support a formulation amendment for Temik (Aldicarb). Transmittal of 1 study. 42523401 Crownover, R. (1992) Aldicarb Solution, Technical Product Identity and Composition...: Lab Project Number: AC-92-009: 41264. Unpublished study prepared by Rhone-Poulenc Ag. 13 P- 42561200 Rhone-Poulenc Ag Comp. (1992) Submission of residue survey in support of registration for Aldicarb (Temik). Transmittal of 4 studies. 42561201 Harrison, S.; Petersen, B.; Barraj, L. (1992) Aldicarb Orange Monitoring Survey Outline. Unpublished study prepared by Rhone-Poulenc Ag Comp. and Technical Assessment Systems Inc. 25 p. 42561202 Brown, E. (1992) Procedures for Florida Orange Processing. Unpublished study prepared by Rhone-Poulenc Ag Comp. 6 p. 42561203 Tomerlin, J.; Petersen, B. (1992) Summary of Aldicarb Monitoring in Florida as of October 23, 1992. Unpublished study prepared by Technical Assessment Systems, Inc. 17 p. 42561204 Benell, N. (1991) Monitoring Data for Aldicarb in Grapefruit and Oranges. Unpublished study prepared by Technical Assessment Systems, Inc. 48 p. 42643900 Rhone-Poulenc (1993) Submission of environmental data in support of the registration for Temik 15G Aldicarb pesticide. Transmittal of 1 study. 42643901 Spare, W. (1993) Soil Photolysis of Aldicarb: Lab Project Number: 1515. Unpublished study prepared by Agrisearch Inc. 175 p. 42659500 Rhone-Poulenc AG Co. (1993) Submission of residue chemistry data concerning Temik under FIFRA 6(A)2. Transmittal of 1 study. 42659501 Davis, W. (1993) Letter Sent to S. Haddad dated on Feb. 2, 1993: Preliminary results from residue trial studies concerning Temik. Prepared by Rhone-Poulenc AG Co. 4 p. 42687100 Rhone-Poulenc (1993) Submission of environmental fate data in support of the registration of TEMIK 15G Brand Aldicarb Pesticides. Transmittal of 2 studies. 42687101 Gustafson, D. (1993) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Analyzed 2Q, 1992 (Exclusive of Long Island, NY): (Quarterly Phase Report): Lab Project Number: 41267: EC-92-182. Unpublished study prepared by Rhone- Poulenc Ag Co. 81 p. 42687102 Gustafson, D. (1993) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Analyzed 3Q, 1992 (Exclusive of Long Island, NY): (Quarterly Phase Report): Lab Project Number: 41308: EC-92-182. Unpublished study prepared by Rhone- Poulenc Ag Co. 140 p. 42722300 Rhone-Poulenc (1993) Submission of residue data in support of the registration of Temik Brand Aldicarb Pesticide. Transmittal of 1 study. 42722301 Tew, E. (1993) Temik: Magnitude of Aldicarb Residues in Sweet Potatoes: Lab Project Number: USA92T02: 41382. Unpublished study prepared by Rhone-Poulenc Ag Co. 164 p. Page 161 of 191 ------- 42725800 Rhone-Poulenc AG Co. (1993) Submission of Environmental Fate Data in Support of FIFRA 6(a)(2) requirements for TEMIK brand Aldicarb Pesticide. Transmittal of 1 Study. 42725801 Davis, W. (1993) Letter sent to S. Haddad dated March 23, 1993 reporting results from sampling of Florida drinking water wells from the Dept. of Environmental Regulation. Prepared by Rhone-Poulenc. 5 p. 42749600 Rhone-Poulenc (1993) Submission of residue data in support of registration for Aldicarb Pesticide. Transmittal of 1 study. 42749601 Petersen, B. (1993) Estimation of Dietary Exposure to Aldicarb in Sweet Potatoes. Unpublished study prepared by Technical Assessment Systems, Inc. 9 p. 42796000 Rhone-Poulenc Ag Co. (1993) Submission of product chemistry data in support of the registration for Temik brand aldicarb pesticide. Transmittal of 2 studies. 42796001 McDaniel, R.; Weiler, D.; Young, K. (1987) Aldicarb Vapor Pressure Evaluation: Lab Project Number: 803P15: 40052. Unpublished study prepared by Rhone-Poulenc Ag Co. 8 p. 42796002 McDaniel, R.; Weiler, D.; Young, K. (1987) Aldicarb: Design and Validation of High Flow Apparatus for Vapor Pressure Determinations: Lab Project Number: 40182: 8710020. Unpublished study prepared by Rhone-Poulenc Ag Co. 20 p. 42797900 Rhone-Poulenc (1993) Submission of environmental fate data in support of the FIFRA 6(a)(2) requirements for aldicarb. Transmittal of 1 study. 42797901 Davis, W. (1993) Letter sent to Office of Pesticide Programs dated May 26, 1993: Aldicarb drinking water detection in Florida, Maine and Wisconsin. Prepared by Rhone-Poulenc. 4 p. 42827800 Rhone-Poulenc Ag Co. (1993) Submission of residue data in support of the registration for TEMIK. Transmittal of 4 studies. 42827801 Tew, E. (1993) TEMIK: Magnitude of Aldicarb Residues in Processed Potatoes: Potato Fractions: Final Report: Lab Project Number: EC-92-211: 44121. Unpublished study prepared by Rhone-Poulenc Ag Co. 229 p. 42827802 Tew, E. (1993) TEMIK: Determination of Variation in Magnitude and Character of Aldicarb Residues in Potatoes from Temik-Treated Fields: Final Report: Lab Project Number: EC-90- 092: EC-90-117: 41207. Unpublished study prepared by Rhone-Poulenc Ag Co. 618 p. 42827803 Tew, E. (1993) TEMIK: Magnitude of Aldicarb Residues in Potatoes Grown from Seed Pieces Injected with Aldicarb Sulfoxide at 1.0 PPM: Final Report: Lab Project Number: EC- 92-208: 41354. Unpublished study prepared by Rhone-Poulenc Ag Co. 90 p. 42827804 Tew, E. (1993) TEMIK: Magnitude of Aldicarb Residues in Potatoes Grown with Available Overhead Irrigation in 1992: Final Report: Lab Project Number: EC-92-180: 41395. Unpublished study prepared by Rhone-Poulenc Ag Co. 283 p. 42935000 Rohm and Haas Company (1993) Submission of Toxicity Data, Residue Chemistry Data, Environmental Fate Data and Product Chemistry Data for Triazamate in Support of an Experimental Use Permit and Petition for Temporary Tolerance on Apples. Transmittal of 71 Studies. Page 162 of 191 ------- 42935042 Parkin, D. (1991) Comparison of IC-50 and T 1/2 of Aldicarb and RH-7988 on Human Plasma Cholinesterase: Lab Project Number: 89P-141: 89R-141. Unpublished study prepared by Rohm and Haas Company, Toxicology Department. 40 p. 43045400 Rhone-Poulenc AG Co. (1993) Submission of toxicology data in support of registration for TEMIK 15G brand Aldicarb Pesticide. Transmittal of 1 study. 43045401 Trutter, J. (1993) Combined Chronic Toxicity and Oncogenicity Study in Rats with Aldicarb Technical: Final Report: Lab Project Number: 656/151: HWA/656/151. Unpublished study prepared by Hazleton Washington, Inc. 3532 p. 43084100 Rhone-Poulenc AG Co. (1994) Submittal of Residue Data in Support of Registration Standard for Aldicarb. Transmittal of 1 study. 43084101 Byrd, J. (1994) A Nature of the Residue Study with (carbon 14)-Aldicarb in Laying Hens: Lab Project Number: 9285C: 819: EC-91-221. Unpublished study prepared by Southwest Bio-Labs, Inc. 348 p. 43110600 Rhone-Poulenc Ag Co. (1994) Submittal of Residue Data in Support of Registration of TEMIK brand Aldicarb Pesticide for Citrus. Transmittal of 1 study. 43110601 Tew, E.; Peterson, B.; Barraj, L.; et al. (1994) Aldicarb Fresh-Market Orange Monitoring Study: Final Report: Lab Project Number: EC-92-216. Unpublished study prepared by Rhone- Poulenc Ag Co. and Morse Labs, Inc. 154 p. 43138500 Rhone-Poulenc Ag Co. (1994) Submission of residue data in support of FIFRA 6(a)(2) requirements for TEMIK 15G brand Aldicarb. Transmittal of 1 study. 43138501 Davis, W. (1994) Letter Sent to Office of Pesticide Programs dated Feb. 17, 1994 concerning monitoring of wells in Florida for possible aldicarb residues. Prepared by Rhone-Poulenc Ag Co. 9 p. 43143800 Rhone-Poulenc AG Co. (1994) Submission of ground water monitoring data in support of FIFRA 6(a)(2) requirements for aldicarb. Transmittal of 1 study. 43143801 Jones, R. (1994) Site Specific Information Related to Aldicarb Well Monitoring Conducted by Rhone-Poulenc AG Company. Unpublished study prepared by Rhone-Poulenc AG Co. 26 P- 43154400 Rhone-Poulenc Ag Co. (1994) Submittal of Residue Data in Support of Registration of Temik Brand Aldicarb Pesticide. Transmittal of 1 study. 43154401 Dean, P. (1994) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Analyzed 4Q, 1992 and 1Q, 1993 (Exclusive of Long Island, NY): Lab Project Number: 44124: EC-92-182. Unpublished study prepared by Rhone-Poulenc Ag Co. 169 p. 43193600 Rhone-Poulenc Ag Co. (1994) Submission of residue data in support of registration for TEMIK Brand Aldicarb Pesticide. Transmittal of 1 study. 43193601 Chancey, E. (1994) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis April 1 through December 31, 1993 (Exclusive of Long Island, NY): Lab Project Number: 44306: EC/92/182. Unpublished study prepared by Rhone- Poulenc Ag Co. 175 p. 43277100 Rhone-Poulenc AG Co. (1994) Submission of residue data in support of FIFRA 6(a)(2) requirements for aldicarb. Transmittal of 1 study. Page 163 of 191 ------- 43277101 Davis, W. (1994) Letter Sent to Office of Pesticide Programs dated June 21, 1994: (Concerning Aldicarb residues above the 10 ppb MCL found in well samples in Florida and Wisconsin). Prepared by Rhone-Poulenc AG Co. 15 p. 43299000 Rhone-Poulenc Ag Co. (1994) Submission of Residue Data in Support of the Conditional Registration of TEMIK 15G. Transmittal of 6 Studies. 43299001 Fish, J. (1994) Comparison of Application Characteristics of Positive Displacement Granular Applicators and Gravity Flow Granular Applicators: Lab Project Number: 44303: USAATG9301. Unpublished study prepared by Rhone-Poulenc Clayton Research Station. 78 P- 43299002 Tew, E. (1994) TEMIK: Magnitude of Aldicarb Residues in Potatoes Resulting from Application Using Gravity Flow and Positive Displacement Application Equipment: Final Study Report: Lab Project Number: USA93T70: 44412: 93-001. Unpublished study prepared by Phone-Poulenc Ag Co. 3255 p. 43299003 Petersen, B.; Barraj, L. (1994) Aldicarb in Potatoes: Dietary Exposure Analysis: Lab Project Number: ALDICARB 94-01. Unpublished study prepared by Techniacl Assessment Systems, Inc. 56 p. 43299004 Rao, K. (1994) TEMIK: Magnitude of Aldicarb Residues in Processed Potato Fractions: Addendum: Chain of Custody Records for Processed Samples: Lab Project Number: EC-92- 211. Unpublished study prepared by Rhone-Poulenc Ag Co. 10 p. 43299005 Rao, K. (1994) Determination of Variation in Magnitude and Character of Aldicarb Residues in Potatoes from Temik-Treated Fields: Addendum: Summary of Sample Storage Intervals: Lab Project Number: EC-90-092: EC-90-117. Unpublished study prepared by Rhone-Poulenc Ag Co. 6 p. 43299006 Rao, K. (1994) Aldicarb-Stability of Residues on Frozen Potato Processed Fractions: Addendum: Quantitative Data Tables & Example Chromatograms: Lab Project Number: EC- 92-201. Unpublished study prepared by Rhone-Poulenc Ag Co. 70 p. 43325400 DuPont Agricultural Products (1994) Submission of environmental fate data in support of registration standard for methomyl. Transmittal of 3 studies. 43325402 Smelt, J.; Dekker, A.; Leistra, M.; et al. (1983) Conversion of four carbamoyloximes in soil samples from above and below the soil water table. Pesticide Science 14:173-181. 43325403 Bromilow, R.; Briggs, G.; Williams, M. et al. (1986) The role of ferrous ions in the rapid degradation of oxamyl, methomyl, and aldicarb in anaerobic soils. Pesticide Science 17:535- 547. 43346700 Rhone-Poulenc Ag Co. (1994) Submission of Residues in the Environment Data in Support of TEMIK Brand Aldicarb Registrations. Transmittal of 1 Study. 43346701 Jones, R. (1994) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis April 1 Through June 30, 1994: (Quarterly Phase Report): Lab Project Number: EC-92-182: 44462. Unpublished study prepared by Rhone-Poulenc Ag Co. 103 p. 43385000 Rhone-Poulenc Ag Co. (1994) Submission of residue and exposure data in support of registration for TEMIK. Transmittal of 2 studies. Page 164 of 191 ------- 43385001 Tew, E. (1994) TEMIK: Magnitude and Distribution of Aldicarb Residues in Potatoes From the Mid-Row Areas of 1993 Florida Test Plots Established with Positive Displacement Application (PDA) Equipment: Final Report: Lab Project Number: US94T02R: 44514. Unpublished study prepared by Morse Lab., Inc. 157 p. 43385002 Petersen, B.; Barraj, L. (1994) Aldicarb in Potatoes: Dietary Exposure Analyses: Revised Report: Lab Project Number: ALDICARB/94/01. Unpublished study prepared by Rhone- Poulenc Ag Co. 56 p. 43442300 Rhone-Poulenc Ag Co. (1994) Submission of toxicity data in support of Data Call-in for Temik Brand Aldicarb Pesticide. Transmittal of 5 studies. 43442301 Robinson, K.; Brooks, W.; Broxup, B. (1994) An Acute Study of the Potential Effects of Orally Administered Aldicarb, Technical Grade, on Behavior and Neuromorphology in Rats: Lab Project Number: 97235. Unpublished study prepared by Bio-Research Lab. Ltd. 712 p. 43442302 Robinson, K.; Brooks, W.; Broxup, B. (1994) ATime of Peak Behavioral Effects Study of a Single Oral Administration of Aldicarb, Technical Grade, in Rats: Lab Project Number: 97236. Unpublished study prepared by Bio-Research Lab. Ltd. 278 p. 43442303 Robinson, K.; Broxup, B. (1994) An Acute Benchmark-Dose Toxicity Study of Orally Administered Aldicarb, Technical Grade, in Rats: Lab Project Number: 97277. Unpublished study prepared by Bio-Research Lab. Ltd. 65 p. 43442305 Brooks, W.; Broxup, B. (1994) An Acute Study of the Time Course of Cholinesterase Inhibition by Aldicarb Technical, Aldicarb Sulfoxide and Aldicarb Sulfone in the Rat: Lab Project Number: 97352. Unpublished study prepared by Bio-Research Lab. Ltd. 358 p. 43453800 Rhone-Poulenc Ag Co. (1994) Submission of Residue Data in Support of Aldicarb Registration Standard. Transmission of 1 Study. 43453801 Jones, R. (1994) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis July 1 Through September 30, 1994: Lab Project Numbers: EC-92-182: 44559. Unpublished study prepared by Rhone-Poulenc Ag Company. 100 p. 43575100 Rhone-Poulenc Ag Co. (1995) Submission of Toxicity Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43575101 Tyl, R.; Marr, M.; Myers, C. (1995) Modified Dominant Lethal Evaluation of Aldicarb Administered in the Feed to CD (Sprague-Dawley) Rats: Final Report: Lab Project Numbers: 65C-5880. Unpublished study prepared by Research Triangle Institute. 323 p. 43591700 E.I. du Pont de Nemours & Co. (1995) Submission of Pesticide Fate & Residues in the Environment and Exposure/Risk to Non-Target Organisms Data in Support of the Atrazine, Simazine, and Cyanazine Registration Standards. Transmittal of 13 Studies. 43591710 Georgia Agribusiness Council. (1995) What's in a number EPA needs to return to the basics: Well sampling by county. The Predicate, p. 1. 43599300 Rhone-Poulenc Ag Co. (1995) Submission of Exposure Data in Support of Aldicarb Registration Standard. Transmittal of 3 Studies. 43599301 Petersen, B.; Barraj, L. (1994) Aldicarb in Potatoes: Dietary Exposure Analyses: Lab Project Number: ALDICARB 94-01. Unpublished study prepared by TAS, Inc. 56 p. Page 165 of 191 ------- 43599302 Petersen, B.; Barraj, L. (1994) Aldicarb in Potatoes: Dietary Exposure Analyses: Revised Report: Lab Project Number: ALDICARB 94-01. Unpublished study prepared by TAS, Inc. 56 p. 43599303 Petersen, B.; Barraj, L. (1995) Aldicarb in Potatoes: Dietary Exposure Analyses. Unpublished study prepared by TAS, Inc. 18 p. 43608800 Monsanto Co. (1995) Submission of Residue in the Environment Data in Support of FIFRA 6(a)(2) for Alachlor and Atrazine. Transmittal of 1 Study. 43608801 Weppelman, R. (1995) Letter sent to Office of Pesticide Programs dated April 6, 1995 transmitting a report from the Tennessee Dept. of Agriculture describing the results of their ground water monitoring program for 1994. Prepared by Monsanto, The Agricultural Group. 7 p. 43617800 Ciba-Geigy Corp. (1995) Submission of Residues in the Environment and Hazard to Aquatic Organisms Data in Support of FIFRA 6(a)(2) for Diazinon. Transmittal of 9 Studies. 43617801 Ross, L. (1991) Preliminary Results of the San Joaquin River Study: March and April, 1991: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 17 p. 43617802 Ross, L. (1992) Preliminary Results of the San Joaquin River Study: Summer 1991: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 15 p. 43617803 Ross, L. (1992) Preliminary Results of the San Joaquin River Study: Winter 1991-2: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 17 p. 43617804 Ross, L. (1993) Preliminary Results of the San Joaquin River Study: Spring 1992: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 14 p. 43617805 Ross, L. (1993) Preliminary Results of the San Joaquin River Study: Summer 1992: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 15 p. 43617806 Ross, L. (1993) Preliminary Results of the San Joaquin River Study: Winter 1992-3: (Diazinon, Ethyl Parathion, Carbaryl, Dimethoate, and Carbofuran...). Unpublished study prepared by State of California, Dept. of Pesticide Regulation. 16 p. 43617808 Nordmark, C. (1994) Four River Monitoring Protocol: Revised: (Includes "Preliminary Results of the Four River Study, Sacramento River, Winter/Spring 1993-1994"). Unpublished study prepared by California Department of Pesticide Regulation. 13 p. 43623700 Rhone-Poulenc Ag Co. (1995) Submission of Residues in the Environment Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43623701 Denny, J.; Jones, R. (1995) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis October 1 Through December 31, 1994: Lab Project Number: EC-92-182: 44683. Unpublished study prepared by Rhone-Poulenc Ag Co. 60 p. 43628100 Ciba-Geigy Corp. (1995) Submission of Residues in the Environment Data in Support of FIFRA 6(a)(2) for Various Pesticides Registered to Ciba. Transmittal of 1 Study. Page 166 of 191 ------- 43628101 Shahane, A. (1994) Pesticide Detections in Surface Waters of Florida. Unpublished study prepared by Florida Dept. of Agriculture and Consumer Services. 9 p. 43633400 E.I. du Pont de Nemours & Co., Inc. (1995) Submission of Toxicology and Residue Data in Support of the Special Review for Atrazine, Simazine and Cyanazine. Transmittal of 5 Studies. 43633401 Heindel, I; Chapin, R.; Gulati, D. et al. (1993) Assessment of the reproductive and developmental toxicity of pesticide/fertilizer mixtures based on confirmed pesticide contamination in California and Iowa groundwater. Fundamental and Applied Toxicology 22:605-621. 43649200 Rhone-Poulenc Ag Co. (1995) Submission of Pesticide Misuse and Toxicity Data in Support of FIFRA 6(a)(2) for Temik (Aldicarb). Transmittal of 1 Study. 43649201 Davis, W. (1995) Letter Sent to D. Edwards dated May 13, 1995: TEMIK 15G brand Aldicarb pesticide: (three dog poisoning incidents and summary of 13 week oral neurotoxicity test in rats preliminary information). Prepared by Rhone-Poulenc Ag Co. 2 p. 43681500 Rhone-Poulenc Ag Co. (1995) Submission of risk/exposure data in support of reregistration for TEMIK 15G (Aldicarb). Transmittal of 1 study. 43681501 Barraj, L.; Petersen, B. (1995) Estimation of the Potential Exposure To Aldicarb in Foods: Lab Project Number: ALDICARB 95-01. Unpublished study prepared by TAS, Inc. 22 p. 43702800 Rhone-Poulenc Ag Co. (1995) Submission of Exposure Data in Support of Aldicarb Registration Standard. Transmittal of 1 Study. 43702801 Barraj, L.; Petersen, B. (1995) Estimation of the Potential Exposure to Aldicarb in Foods: Lab Project Number: ALDICARB 95-01. Unpublished study prepared by TAS, Inc. 28 p. 43761500 Rhone-Poulenc Ag Co. (1995) Submission of Residues in the Environment Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43761501 Denny, I; Jones, R. (1995) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis January 1 through June 30, 1995: (Exclusive of Long Island): Lab Project Number: EC-92-182: 44815: 92682. Unpublished study prepared by Rhone-Poulenc Ag Co. 57 p. 43805700 Rhone-Poulenc Ag Co. (1995) Submission of Environmental Fate Data in Support of the Registration Standard for Aldicarb. Transmittal of 2 Studies. 43805701 Skinner, W.; Jao, N. (1995) Anaerobic Aquatic Metabolism of (Carbon 14)-Aldicarb: Lab Project Number: 468W-1: 468W: EC-94-275. Unpublished study prepared by PTRL West, Inc. 138 p. 43805702 Skinner, W. (1995) Aerobic Aquatic Metabolism of (Carbon 14)-Aldicarb: Lab Project Number: 467W-1: 467W: EC-94-274. Unpublished study prepared by PTRL West, Inc. 141 P- 43829600 Rhone-Poulenc Ag Co. (1995) Submission of Toxicology Data in Support of FIFRA 6(a)(2) and the Registration Standard for Aldicarb. Transmittal of 2 Studies. Page 167 of 191 ------- 43829601 Weiler, M. (1995) Developmental Neurotoxicity Study with Aldicarb in Rats: Final Report: Lab Project Number: HWI6224-213. Unpublished study prepared by Hazleton Wisconsin, Inc. 891 p. 43829602 Robinson, K.; Brooks, W.; Broxup, B. (1995) A 13-Week Study of the Potential Effects of Orally Administered Aldicarb Technical on Behavior, Neurochemistry and Neuromorphology in Rats: Lab Project Number: 97234. Unpublished study prepared by Bio-Research Labs, Ltd. 825 p. 43842000 FMC Corp. (1995) Submission of Residue and Exposure: Reentry Protection Data in Support of the Registration Standard for Carbofuran. Transmittal of 1 Study. 43842001 Carlson, D. (1995) Soil Residue Dissipation, Dermal Passive Dosimetry Exposure and Inhalation Passive Dosimetry Exposure-Potatoes: Justification for Waiver of Carbofuran Data Call-in. Unpublished study prepared by FMC Corp. 71 p. 43842400 Rhone-Poulenc Ag Co. (1995) Submission of Residue Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43 842401 Gillings, O. (1995) Storage Stability of Aldicarb Residues in Green Coffee Beans, Roasted Coffee Beans, and Instant Coffee: Lab Project Number: EC-94-293: 44916. Unpublished study prepared by Rhone-Poulenc Ag Co. 226 p. 43844700 Rhone-Poulenc Ag Co. (1995) Submission of Residue Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43844701 Andrawes, N.; Smitley, C. (1995) Aldicarb-Stability of Residues on Frozen Soybean Processed Fractions: Addendum: Quantitative Data Tables & Example Chromatograms: Lab Project Number: EC-92-200: SOP-90025. Unpublished study prepared by Rhone-Poulenc Ag Co. 55 p. 43852500 Rhone-Poulenc Ag Co. (1995) Submission of Exposure Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 43852501 Rosenheck, L.; Schuster, L. (1995) Worker Loader and Applicator Exposure to Temik 15G: Lab Project Number: 94388. Unpublished study prepared by ABC Labs, Inc., Pan-Ag Div. 344 p. 43902400 Rhone-Poulenc Ag Co. (1996) Submission of Fate in Plants Data in Support of the Registration Standard for Aldicarb. Transmittal of 1 Study. 43902401 Hathcock, T.; Kimmel, E.; Ruzo, L. (1996) A Metabolism Study with (Carbon 14)-Aldicarb in Citrus (Lemon Trees): Lab Project Number: 478W-1: 478W: EC-94-278. Unpublished study prepared by PTRL West, Inc. 234 p. 43961100 U.S. EPA (1996) Submission of Toxicity Data on 17 Pesticides. Transmittal of 1 Study. 43961101 McCann, I; Teeters, W.; Urban, D. et al. (1981) A short-term dietary toxicity test on small mammals, p. 132-142 of the Second Conference of Avian and Mammalian Wildlife Toxicology, Lamb, D.; Kenaga, E. Eds.; Published in American Society for Testing and Materials, ASTM STP 757; 1981. 43970000 Rhone-Poulenc Ag Co. (1996) Submission of Residue Chemistry Data in Support of TEMIK Brand 15G Aldicarb Pesticide Registration Standard. Transmittal of 1 Study. Page 168 of 191 ------- 43970001 Wells-Knecht, M; Andrawes, N. (1996) (Carbon 14)-Aldicarb Metabolism in Citrus (Lemon Trees): Supplemental Report to MRID No. 43902401: Lab Project Number: EC-95-320. Unpublished study prepared by Rhone-Poulenc Ag Company. 286 p. 43988300 Rhone-Poulenc Ag Co. (1996) Submission of Pesticide Fate in the Environment Data in Support of Reregistration of TEMIK Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 43988301 Jones, R. (1996) Measurement of Aldicarb Degradation and Movement for Winter Applications to Grapes: Lab Project Number: 45049. Unpublished study prepared by Rhone- Poulenc Ag Co. 131 p. 43994400 Rhone-Poulenc Ag Co. (1996) Submission of Pesticide Fate & Residues in the Environment Data in Support of Registration Standard for TEMIK Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 43994401 Denny, I; Jones, R. (1996) Potable Well Water Monitoring for Aldicarb in the United States: Results for Samples Submitted for Analysis July 1 through December 31, 1995: (Exclusive of Long Island, NY): Lab Project Number: 44991: EC-92-182: SOP 90009. Unpublished study prepared by Rhone-Poulenc Ag Co. 58 p. 44005000 Rhone-Poulenc Ag Co. (1996) Submission of Environmental Fate Data in Support of the Aldicarb Registration Standard. Transmittal of 1 Study. 44005001 Das, Y. (1990) Metabolism of (S-Methyl-(carbon 14))Aldicarb Under Aerobic Soil Conditions: Lab Project Number: EC-90-099: 90020. Unpublished study prepared by Innovative Scientific Services, Inc. 85 p. 44196700 Rhone-Poulenc Ag Co. (1997) Submission of Residue Data in Support of the Amended Registration of TEMIK Brand 15G NW Aldicarb Pesticide. Transmittal of 1 Study. 44196701 Tew, E. (1996) TEMIK: Magnitude of Aldicarb Residues in Pacific Northwest Potatoes Harvested 120 Days After an At-Planting, In-Furrow Application of TEMIK 15G at 3 Ib ai/Acre: Final Report: Lab Project Number: 96T10525: 45187: 10525-01. Unpublished study prepared by Rhone-Poulenc Ag co. 414 p. 44204900 Rhone-Poulenc Ag Co. (1997) Submission of Exposure/Risk Data in Support of the Amended Registrations of Temik Brand 15G NW Aldicarb Pesticide and Temik Brand 15G NW Aldicarb Pesticide Lock 'n Load Closed Handling System. Transmittal of 2 Studies. 44204901 Barraj,L. (1996) Assessing the Impact of Reducing the PHI for Aldicarb on Potatoes to 120 Days: Comparison of the Potential Exposure to Aldicarb Using Monitoring Data and Data from the 120 Day PHI Field Trial Study. Unpublished study prepared by Novigen Sciences, Inc. 14 p. 44204902 Barraj, L. (1996) Using the 1996 Florida and PNW Monitoring Data to Estimate the Potential Exposure to Aldicarb on Potatoes. Unpublished study prepared by Novigen Sciences, Inc. 15 P- 44209000 Rhone-Poulenc Ag Co. (1997) Submission of Residue Data in Support of the Registration of Temik Brand Aldicarb Pesticide. Transmittal of 1 Study. 44209001 Tew, E. (1997) Temik: Pacific Northwest Potato Farmgate Study: Amended Final Report: Lab Project Number: 96T11379: 45217. Unpublished study prepared by Rhone-Poulenc Ag Co. 194 p. Page 169 of 191 ------- 44244700 Rhone-Poulenc Ag Co. (1997) Submission of Residue Data in Support of the Amended Registration for Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 44244701 Tew, E. (1997) Temik: Magnitude of Residues in Potatoes from Regions V and IX Harvested 120 Days After an At-Planting Application of Temik 15G at 3 Ib ai/acre: Lab Project Number: 96T11218: 45257: 11218-01. Unpublished study prepared by Rhone-Poulenc Ag Co. 447 p. 44287600 Rhone-Poulenc Ag Co. (1997) Submission of Exposure and Risk Assessment Data in Support of the Reregistration of TEMIK Brand Aldicarb Pesticide. Transmittal of 1 Study. 44287601 Barraj, L. (1997) Estimating the Potential Dietary Exposure to Aldicarb in Foods: Lab Project Number: ALDICARB 97-03. Unpublished study prepared by Novigen Sciences, Inc. 24 p. 44335700 Rhone-Poulenc Ag Co. (1997) Submission of Exposure/Risk Data in Support of the Label Amendments and Crop Group Petition for Temik Brand 15G Aldicarb Pesticides in/on Citrus. Transmittal of 1 Study. 44335701 Barraj, L. (1997) Estimating the Potential Aggregate Exposure to Aldicarb in Food and Water: Lab Project Number: ALDICARB 97-04. Unpublished study prepared by Rhone- Poulenc Ag Co. 28 p. 44338600 Rhone-Poulenc Ag Co. (1997) Submission of Exposure/Risk Data in Support of the Label Amendment for Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 44338601 Barraj, L.; Petersen, B. (1997) Assessing the Impact of the Temik Label Expansion on the Potential Exposure to Aldicarb in Potatoes: Lab Project Number: ALDICARB 97-02. Unpublished study prepared by Novigen Sciences, Inc. 18 p. 44341800 Rhone-Poulenc Ag Co. (1997) Submission of Residue Data in Support of the Amended Registration for Temik Brand 15G Aldicarb Pesticide and Tolerance Petition for Aldicarb in/on Citrus. Transmittal of 1 Study. 44341801 Tew, E. (1997) Temik: Florida Potato Farmgate Study: Lab Project Number: 97T12422: 45366. Unpublished study prepared by Rhone-Poulenc Ag Co. 287 p. {OPPTS 860.1500} 44524600 Rhone-Poulenc AG Co. (1998) Submission of Exposure and Risk Assessment Data in Support of the Registration of Temik Brand Aldicarb Pesticide. Transmittal of 1 Study. 44524601 Barraj, L.; Petersen, B. (1998) Using the Elapsed Time Approach to Estimate the Potential Aggregate Exposure to Aldicarb in Food and Water: Lab Project Number: ALDICARB 98- 01. Unpublished study prepared by Rhone-Poulenc Ag Co. 30 p. 44580900 Rhone-Poulenc Ag Company (1998) Submission of Residue Chemistry Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 44580901 Jones, R.; Scarborough, T. (1998) Rhone-Poulenc Ag Company Response to April 9, 1998 EFED Requests for Information on Aldicarb: Lab Project Number: AS-98-01: RTP-2162. Unpublished study prepared by Rhone Poulenc Ag Co. 111 p. 44585400 U.S. Environmental Protection Agency (1998) Submission of Environmental Fate, Toxicity, and Exposure Data in Support of the Reregistration of Organophosphorus and Carbamate Compounds. Transmittal of 16 Studies. 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Unpublished study prepared by Industrial Bio-Test Labs, Inc. 50 p. 44598707 Kohn, F. (1964) Two-Year Chronic Oral Toxicity Study of (inert ingredients) in Albino Rats: Lab Project Number: 92-2C. Unpublished study prepared by Industrial Bio-Test Labs., Inc. 114 p. 44598708 Cervenka, H. (1964) Two-Year Chronic Oral Toxicity of (inert ingredients) in Beagle Dogs: Lab Project Number: 92-2D. Unpublished study prepared by Industrial Bio-Test Labs., Inc. 83 p. 44598709 Safe, S. (1994) Environmental and dietary (inert ingredients) and human health: is there a problem Environmental Health Perspectives 13(103):346-351. 44613200 Rhone-Poulenc (1998) Submission of Environmental Fate Data in Support of the Registration of Temik 15G Brand Aldicarb Pesticide. Transmittal of 1 Study. 44613201 Norris, F. (1998) Aldicarb: Mobility in Soil After Application to Florida Ridge Soils Under the Best Management Plan: Lab Project Number: 96T09666: 45613: 95-199-001. Unpublished study prepared by HydroScience, Inc. and Agvise Laboratories, Inc. 1586 p. 44636100 Rhone Poulenc Ag Company (1998) Submission of Toxicity Data in Support of the Registration of Temik 15 G. Transmittal of 1 Study. Page 171 of 191 ------- 44636101 Tyl, R.; Ross, W.; Myers, C. (1998) Assessment of Cholinesterase Activity in CD Rats Following Topical Application of Temik 15G Grit for Three Weeks: Final Report: Lab Project Number: 65C-7202. Unpublished study prepared by Research Triangle Institute. 160 p. {870.3200} 44678000 Rhone-Poulenc Ag Company (1998) Submission of Environmental Fate and Residue Chemistry Data in Support of the Reregistration of the Aldicarb Containing Product Temik 15G Brand Aldicarb Pesticide. Transmittal of 1 Study. 44678001 Norris, F.; Pickrell, S. (1998) Aldicarb: Mobility in Soil After Application to Florida Ridge Soils Under the Best Management Plan: Final Report: Lab Project Number: 96T09666: 45640: 95-119-001. Unpublished study prepared by Rhone-Poulenc Ag Company, and HydroScience, Inc. 1917 p. 44699600 U.S. Environmental Protection Agency (1998) Submission of Toxicity, and Risk Assessment and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 3 Studies. 44699601 Goldman, L.; Beller, M.; Jackson, R. (1990) Aldicarb food poisonings in California, 1985- 1988: toxicity estimates for humans. Archives of Environmental Health 45(3): 141-147. 44699602 Goldman, L.; Smith, D.; Neutra, R. et al. (1990) Pesticide food poisoning from contaminated watermelons in California, 1985 (Aldicarb). Archives of Environmental Health 45(4): 229- 236. 44699603 Hirsch, G.; Mori, B.; Morgan, B. et al. (1987) Report of illnesses caused by aldicarb- contaminated cucumbers. Food Additives and Contaminants 5(2): 155-160. 44719300 Rhone-Poulenc Ag Company (1998) Submission of Risk Assessment and Exposure Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G NW Aldicarb Pesticide, and Temik Brand 15G CP Aldicarb Pesticide. Transmittal of 1 Study. 44719301 Barraj, L.; Walters, J. (1998) Assessment of the Potential Acute Dietary Exposure to Aldicarb in Food and Water: Lab Project Number: ALDICARB 98-02. Unpublished study prepared by Rhone-Poulenc Ag Company. 99 p. 44734900 Rhone-Poulenc AG Company (1999) Submission of Toxicity Data in Support of the Reregistration of the Aldicarb Containing Product Temik 15G Grit. Transmittal of 1 Study. 44734901 Tyl, R.; Ross, W.; Myers, C. (1998) Assessment of Cholinesterase Activity in CD Rats Following Topical Application of Temik 15G for Three Weeks: Amended Final Report: Lab Project Number: 65C-7202: RT98-GRIT: RTI-671. Unpublished study prepared by Rhone- Poulenc Ag Company. 164 p. {OPPTS 870.3200} 44845100 Carbamate Market Basket Survey Task Force (1999) Submission of Residue Chemistry Data in Support of the Registration of Carbamate. Transmittal of 1 Study. 44845101 Carringer, S. (1999) Carbamate Insecticide Market Basket Survey: Interim Study Report: Lab Project Number: TCI-99-001: CARDC 1336: ML98-0768-CMB. Unpublished study prepared by Novigen Sciences, Inc. and Morse Laboratories, Inc. 471 p. 44847400 Rhone-Poulenc Ag Company (1999) Submission of Product Chemistry, Toxicity, Risk Assessment and Exposure Data in Support of the Petition for Tolerance of Aldicarb in/on Bananas. Transmittal of 5 Studies. Page 172 of 191 ------- 44847401 Helfant, L. (1999) Product Chemistry: Banana In-Plant System: Lab Project Number: 98005LJH. Unpublished study prepared by Rhone-Poulenc Ag Co. 58 p. {OPPTS 830.1550, 830.1620, 830.1670, 830.1800, 830.6302, 830.6304, 830.6315, 830.7300, 830.7000} 44847402 Carringer, S. (1998) Temik 15 GG: Magnitude of Total Aldicarb Residues in Banana RAC from Stem Injection Treatment (Central and South America): Final Study Report: Lab Project Number: 97T112971: 45655: 12971-01. Unpublished study prepared by Rhone-Poulenc Ag Co. and McKenzie Laboratories, Inc. 417 p. {OPPTS 860.1500} 44847403 Carringer, S. (1998) Temik 15 GG: Magnitude of Total Aldicarb Residues in Banana Processed Fractions from Stem Injection Treatment (Central and South America): Lab Project Number: 97TI13621: 45656: 13621-01. Unpublished study prepared by Rhone-Poulenc Ag Co. and McKenzie Laboratories, Inc. 268 p. 44847404 Szuter, S. (1998) Aldicarb: Storage Stability of Total Aldicarb Residues in Banana RAC Pulp and Peel and the Processed Fractions of Puree and Chips: Interim Study Report: Lab Project Number: MK12-97: 90021. Unpublished study prepared by Rhone-Poulenc Ag Co. and McKenzie Laboratories, Inc. 327 p. {OPPTS 860.1380} 44847405 Barraj, L. (1999) Assessment of the Potential Acute Dietary Exposure to Aldicarb in Water and Foods, Including Bananas: Lab Project Number: 99-01. Unpublished study prepared by Novigen Sciences, Inc. 118 p. 44860100 Rhone-Poulenc Ag Company (1999) Submission of Reduced-Risk Pesticide Rationale for Aldicarb. Transmittal of 1 Study. 44860101 Aldridge, K.; Ortego, L.; Rieth, J. et al. (1999) Reduced Risk and Organophosphate (OP) Replacement Rationale for Aldicarb Use on Bananas-the Banana In-Plant System: Lab Project Number: AS-07-99. Unpublished study prepared by Rhone-Poulenc Ag Company. 251 p. 44929700 Carbamate Market Basket Survey Task Force (1999) Submission of Residue Data in Support of the Registrations of the Aldicarb, Carbaryl, Methomyl, Oxamyl, and Thiodicarb Containing Products Temik 15G CP, Temik 15G Lock'n Load, Temik 15G Lock'n Load-CA, Temik 15G NW, Sevin 4F, Sevin 80WSP, Sevin XLR Plus, Lannate LV, Lannate SP, Vydate C-LV, Vydate L, and Larvin 3.2. Transmittal of 1 Study. 44929701 Carringer, S. (1999) Carbamate Insecticide Market Basket Survey: Interim Study Report- No.2: Lab Project Number: TCI-99-001: ML98-0768-CMB: TCI-99-001/CARDC 133. Unpublished study prepared by Novigen Sciences, Inc.; Morse Laboratories, Inc.; Colorado Analytical Research and Development Corporation. 546 p. 44985600 Carbamate Market Basket Survey Task Force (1999) Submission of Residue Chemistry Data in Support of the Reregistration of Carbamate Containing Products Temik 15G, 15G Lock'n Load, 15G Lock'n Load and 15G NW, Sevin 4F, 80WSP and XLR Plus, Lannate LV and SP, Vydate C-LV and L and Larvin 3.2. Transmittal of 1 Study. 44985601 Carringer, S. (1999) Carbamate Insecticide Market Basket Survey: Interim Report-No. 3: Lab Project Number: TCI-99-001. Unpublished study prepared by Novigen Sciences, Inc., and Morse Laboratories, Inc. 642 p. 45068600 U.S. EPA (2000) Submission of Toxicity Data in Support of the Registration of Aldicarb and Methamidophos. Transmittal of 1 Study. 45068601 Moser, V. (1999) Comparison of Aldicarb and Methamidophos Neurotoxicity at Different Ages in the Rat: Behavior and Biochemical Parameters. Toxicology and Applied Pharmacology 157:94-106. Page 173 of 191 ------- 45068700 U.S. EPA (2000) Submission of Toxicity Data in Support of the Registration of Aldicarb and Methamidophos. Transmittal of 1 Study. 45068701 U.S. EPA (1999) Letters to the Editor. Toxicology and Applied Pharmacology 161:302-305. 45079700 Aventis CropSciences (2000) Submission of Product Chemistry, and Toxicity Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 15G Aldicarb Pesticide for Use on Citrus Only, Temik 15G Aldicarb Pesticide for Use on Potatoes Only, and Temik Brand 10G Aldicarb Pesticide. Transmittal of 6 Studies. 45079701 Tobia, A. (2000) Aldicarb: Absence of Justification for Requiring a FQPA Factor for Aldicarb: Toxicology. Unpublished study prepared by Aventis CropScience. 54 p. 45079702 Tobia, A. (2000) Aldicarb: Response to FIFRA SAP Report of February, 1999: Toxicology. Unpublished study prepared by Aventis CropScience. 31 p. 45079703 Lunchick, C.; Tobia, A. (2000) Rebuttal to the Aldicarb Data Evaluation Record for the 21 - Day Dermal Toxicity Study Assessment of Cholinesterase Activity in CD Rats Following Topical Applications of Temik 15G Grit for Three Weeks MRID# 44636101. And Rebuttal to EPA 10/01/99 Review of: Additional Aldicarb 5 Day Rat Dermal Toxicity Study Protocol (D259834 Aldicarb (098301)): Lab Project Number: 01ALDOO/ADVENTIS: D259834 ALDICARB: 098301. Unpublished study prepared by Aventis CropScience. 24 p. 45079704 Tyl, R.; Ross, W.; Myers, C. (2000) Assessment of Cholinesterase Activity in CD Rats Following Topical Applications of Temik 15G Grit for One Week: Final Report: Lab Project Number: 65C-07594: RTI-749. Unpublished study prepared by Research Triangle Institute. 128 p. {OPPTS 870.3200} 45079705 Tyl, R.; Anderson, S. (2000) The Toxicokinetics of Peripheral Cholinesterase Inhibition from Orally Administered Aldicarb in Adult Male CD Rats: Final Report: Lab Project Number: 65C-07532-100: 65C-07532-200: RTI-726. Unpublished study prepared by Research Triangle Institute. 108 p. {OPPTS 870.8500} 45079706 Linchick, C.; Powell, G. (2000) Temik Brand ISO-Quality Control Data on Dust Control of Gypsum and Grit Formulations: Lab Project Number: 02ALDOO/AVENTIS. Unpublished study prepared by Aventis Crop Science. 101 p. 45150700 U.S. Environmental Protection Agency (2000) Submission of Toxicity Data in Support of the Registration of Aldicarb. Transmittal of 1 Study. 45150701 Moser, V. (1999) Aldicarb Replication Study. Unpublished study prepared by US EPA, National Health and Environmental Effects Research Lab. 403 p. 45164701 Carringer, S. (2000) Carbamate Insecticide Market Basket Survey: Final Report: Lab Project Number: TCI-99-001: METH-118: 98-03. Unpublished study prepared by Novigen Sciences, Inc. and Morse Laboratories. 3359 p. 45167200 Aventis CropScience (2000) Submission of Risk Assessment and Exposure Data in Support of the Reregistration of Ethoprop. Transmittal of 1 Study. 45167201 Urtizberea, M. (1999) Worker Exposure Study During Application in Banana Plantation with Temik 10G: Lab Project Number: SA 98337: RPS/ALD/98072. Unpublished study prepared by ADME Bioanalyses. 156 p. {OPPTS 875.1000} Page 174 of 191 ------- 45178000 Aventis CropScience (2000) Submission of Environmental Fate Data in Support of the Reregistration of Aldicarb. Transmittal of 2 Studies. 45178001 Ramanarayanan, T. (2000) Kinetics Modeling of Degradation of Aldicarb and its Metabolites in Anaerobic Aquatic Condition: Lab Project Number: B002970. Unpublished study prepared by Aventis CropScience. 30 p. 45178002 Holmsen, J. (2000) Response to EPA Aldicarb Data Evaluation Record 2, Anaerobic Aquatic Metabolism of (carbon-14) Aldicarb (Agency/EFED Review dated May 18, 2000): Lab Project Number: B002980. Unpublished study prepared by Aventis CropScience. 21 p. 45181800 Aventis CropScience (2000) Submission of Product Chemistry Data in Support of the Petition for Tolerance of Aldicarb in/on Bananas. Transmittal of 3 Studies. 45181801 Szuter, S. (2000) Aldicarb: Storage Stability of Total Aldicarb Residues in Banana RAC Pulp and Peel and the Processed Fractions of Puree and Chips: Final Report: Lab Project Number: MK12-97. Unpublished study prepared by McKenzie Laboratories, Inc. 415 p. {OPPTS 860.1380} 45181802 Carringers, S. (2000) TEMIK 15GC: Magnitude of Total Aldicarb Residues in Banana RAC from Stump Implant Treatment, Year 2 (Central and South America): Final Report: Lab Project Number: 97T15173: B002854: 15173-01. Unpublished study prepared by McKenzie Laboratories, Inc. 312 p. {OPPTS 860.1500} 45181803 Gough, S. (2000) Aldicarb/Banana/ Residue Decline/1998-99: Final Study Report: Lab Project Number: 46028: 98T16299: 16299-01. Unpublished study prepared by McKenzie Laboratories, Inc. 223 p. 45185000 Aventis CropScience (2000) Submission of Toxicity Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 45185001 Weiler,M. (2000) Addendum to Developmental Neurotoxicity Study with Aldicarb in Rats: Lab Project Number: 03 ALDOOO/AVENTIS. Unpublished study prepared by Covance Laboratories, Inc. 413 p. {OPPTS 870.6300} 45205500 Aventis CropScience. (2000) Submission of Exposure Data in Support of the Petition for Tolerance of Aldicarb in/on Bananas. Transmittal of 1 Study. 45205501 Vergnon, J. (2000) Worker Exposure Study During Application in Banana Plantation with Aldicarb Banana In-Plant System Sachets: Lab Project Number: RPS/ALD/99051: 99011 HI. Unpublished study prepared by Aventis Cropscience. 176 p. 45433200 FIFRA Environmental Model Validation Task Force (2001) Submission of Exposure Assessment Data in Support of the Validation of PRZM. Transmittal of 1 Study. 45433201 Jones, R.; Russell, M. (2001) FIFRA Environmental Model Validation Task Force: Final Report. Unpublished study prepared by FIFRA Environmental Model Validation Task Force. 768 p. 45451400 Aventis CropSciecne (2001) Submission of Toxicity, Risk Assessment and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 45451401 Tobia, A. (2001) Scientific Response to Issues Raised in the EPA's February 8, 2001 HED HI ARC Report on the Re-Evaluation of Aldicarb. Unpublished study prepared by Aventis CropScience. 289 p. Page 175 of 191 ------- 45467500 Aventis CropScience (2001) Submission of Toxicity Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 45467501 Tyl, R. (2000) Responses to: Health Effects Division Data Evaluation Records (DER No. 013268: Aldicarb, TEMIK 15G Grit 21-Day Dermal Toxicity Study and DER 014169: Aldicarb, TEMIK 15G Grit 5-Day Dermal Toxicity Study): Lab Project Number: 01GSP2001. Unpublished study prepared by Aventis CropScience. 19 p. 45529100 Aventis CropScience (2001) Submission of Environmental Fate Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 45529101 Hodges, L. (2001) Review of the Reregistration Eligibility Decision Draft Chapter on Environmental Fate and Ecological Effects: Aldicarb. Unpublished study prepared by Aventis CropScience. 94 p. 45592100 Aventis CropScience (2002) Submission of Pesticide Use, Environmental Fate, Toxicity and Product Chemistry Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 10% Granular Aldicarb Pesticide for Agricultural Use, Temik 15G Aldicarb Pesticide for Use on Citrus Only, and Temik Brand 15G NW Aldicarb Pesticide for Use on Potato. Transmittal of 17 Studies. 45592101 Scarborough, T. (2001) 1999-2000 TEMIK User Studies. Unpublished study prepared by Aventis CropScience. 78 p. 45592102 McDaniel, R.; Weiler, D. (1987) Aldicarb Vapor Pressure: Lab Project Number: 40052: 803P15. Unpublished study prepared by Rhone-Poulenc Ag Company. 9 p. 45592103 McDaniel, R.; Weiler, D. (1987) Design and Validation of High Flow Apparatus for Vapor Pressure Determinations: Lab Project Number: 40182. Unpublished study prepared by Rhone- Poulenc, Inc. 20 p. 45592106 Allan, J. (2001) The Route and Rate of Degradation of (s-Methyl-(Carbon 14))-Aldicarb in Two Soils under Laboratory Aerobic Conditions at 25 (Degrees Celcius): Interim Report: Lab Project Number: 601YT: B003572. Unpublished study prepared by Aventis CropScience. 120 P- 45592107 Jesudason, P. (2001) Aerobic Aquatic Metabolism of (S-Methyl-(Carbon 14))-Aldicarb Under Laboratory Conditions at 25 Degrees Celcius: Lab Project Number: 602YT: B003556. Unpublished study prepared by Aventis CropScience and AGVISE Laboratories, Inc. 127 p. 45592200 US EPA (2002) Submission of Exposure, Risk, Pesticide Use, Toxicity, Safety, Residue, and Environmental Fate Data. Transmittal of 50 Studies. 45592235 People, S.; Maddy, K.; Smith, C. (1978) Occupational Exposure to Temik (Aldicarb) as Reported by California Physicians for 1974-1976. Veterinary and Human Toxicology 20:321- 324. 45602900 Aventis Cropscience (2002) Submission of Environmental Fate Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 10% Granular Aldicarb Pesticide for Agricultural Use, Temik 15G Aldicarb Pesticide for Use on Citrus Only, Temik Brand 15G Aldicarb Pesticide and Temik Brand 15G NW Aldicarb Pesticide for Use on Potato. Transmittal of 4 of 21 Studies. 45602901 Lemley, A.; Zhong, W. (1983) Kinetics of Aqueous Base and Acid Hydrolysis of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone. Journal of Environmental Science Health B 18(2): 189-206. Page 176 of 191 ------- 45602902 Hansen, I; Spiegel, M. (1983) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone. Environmental Toxicology and Chemistry 2:147-153. 45602903 Lemley, A.; Zhong, W. (1984) Hydrolysis Studies of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone at Parts per billion Levels in Aqueous Mediums. Journal Agricultural Food Chemistry 32:714-719. 45602904 Lightfoot, E.; Thorne, P.; Jones, R. et al. (1987) Laboratory Studies on Mechanisms for the Degradation of Aldicarb, Aldicarb Sulfoxide and Aldicarb Sulfone. Environmental Toxicology and Chemistry 6:377-394. 45632500 Aventis CropScience (2002) Submission of Product Chemistry Data in Support of the Amended Registration of TEMIK Brand 15G Aldicarb Pesticide, TEMIK Brand 15G CP Aldicarb Pesticide, TEMIK Brand 15G Aldicarb Pesticide for Sale and Use in California Only and TEMIK Brand 15G NW Aldicarb Pesticide. Transmitted of 4 Studies. 45632501 Helfant, L. (2002) Temik Brand 15G Aldicarb Pesticide Product Chemistry: Lab Project Number: 021802LJH: B003770. Unpublished study prepared by Aventis CropScience. 33 p. {OPPTS 830.1550, 830.1650} 45649100 Aventis CropScience (2002) Submission of Product Chemistry Data in Support of the Registration of TEMIK Brand 10G Aldicarb Pesticide and TEMIK Brand 10G Aldicarb Pesticide for Agricultural Use. Transmittal of 1 Study. 45649101 Helfant, L. (2002) TEMIK Brand 10G Aldicarb Pesticide Product Chemistry: Lab Project Number: 040102LJH. Unpublished study prepared by Aventis CropScience. 21 p. {OPPTS 830.1550 and 830.1650} 45739800 Aventis CropScience (2002) Submission of Environmental Fate Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 10% Granular Aldicarb Pesticide for Agricultural Use, Temik 15G Aldicarb Pesticide for Use on Citrus Only, Temik Brand 15G Aldicarb Pesticide and Temik Brand 15G NW Aldicarb Pesticide for Use on Potatoe. Transmittal of 2 Studies. 45739801 Allan, J. (2002) The Route and Rate of Degradation of (S-Methyl-(Carbon 14))-Aldicarb in 2 Soils Under Laboratory Aerobic Conditions at 25 Degrees C: Final Report: Lab Project Number: 601YT: B003965. Unpublished study prepared by Aventis CropScience. 167 p. 45739802 Allan, J. (2002) The Route and Rate of Degradation of (S-Methyl-(Carbon 14))-Aldicarb Sulfone in 2 Soils Under Laboratory Aerobic Conditions at 25 Degrees C: Lab Project Number: 607YT: B003573. Unpublished study prepared by Aventis CropScience. 101 p. 45906800 Bayer CropScience (2003) Submission of Environmental Fate Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 10% Granular Aldicarb Pesticide for Agriculture Use, Temik 15G Aldicarb Pesticide for Use on Citrus Only, Temik Brand 15G Aldicarb Pesticide for Sale and Use in California Only, Temik Brand 15G NW Aldicarb Pesticide for Use on Potatoes. Transmittal of 1 Study. 45906801 Allan, J. (2002) The Route and Rate of Degradation of (S-Methyl-Carbon 14)-Aldicarb Sulfone in Two Soils Under Laboratory Aerobic Conditions at 25 (Degrees) C (Amended Report to Study 607YT, Document Number B003573): Lab Project Number: B004162: 607YT: B003573. Unpublished study prepared by Aventis CropScience. 102 p. 46065200 Bayer CropScience (2003) Submission of Product Chemistry, Risk and Exposure Data in Support of the Registration of Temik Brand 15G Aldicarb Pesticide. Transmittal of 3 Studies. Page 177 of 191 ------- 46065201 Helfant, L.; Ligon, R. (2003) Temik Brand 15G Aldicarb Pesticide Product Chemistry. Project Number: PC030417, B004379, CM/62. Unpublished study prepared by Bayer Cropscience LP. 82 p. 46065203 Fish, J. (2003) Temik Brand 15G Aldicarb Pesticide Formulation Development Importance of Formulation on Application Uniformity, Worker Safety and Customer Satisfaction. Project Number: JDF2003/1. Unpublished study prepared by Bayer Cropscience LP. 12 p. 46065204 Ligon, R. (2001) Three Year Storage Evaluation of Temik 15 G Gypsum. Project Number: WOODBINE/061501. Unpublished study prepared by Bayer Cropscience LP. 25 p. 46 100300 Bayer CropScience (2003) Submission of Product Chemistry Data in Support of the Registration of Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 46 10030 1 Lunchick, C. (2003) Bayer CropScience Comments Regarding Dust Content of Bayer Brand Aldicarb Formulations and Its Relationship to Operator Exposure Potential. Project Number: WOODBINE/08180, CL072003. Unpublished study prepared by Bayer Cropscience LP. 68 p. 46 1 3 1000 Bayer CropScience (2003) Submission of Toxicity Data in Support of the Reregistration of the Aldicarb Containing Products Temik Brand 15G Aldicarb Pesticide, Temik 10% Granular Aldicarb Pesticide for Agricultural Use, Temik 15G Aldicarb Pesticide for Citrus Use, Temik Brand 15G Aldicarb for Sale and Use in California Only, and Temik Brand 15G NW Aldicarb Pesticide for Use on Potatoe. Transmittal of 1 Study. 46131001 Cameron, A. (2003) Supplementary Report to: A Safety and Tolerability Study of Aldicarb at Various Dose Levels in Healthy Male and Female Volunteers: Final Report. Project Number: 003237, SOP/REC/030. Unpublished study prepared by Inveresk Research International and BCG (Europe) Ltd. 136 p. Bayer CropScience LP (2004) Submission of Residue, Risk and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. Barraj, L.; Tomerlin, J.; Daniels, C. (2001) Assessment of the Potential Acute Dietary Exposure to Aldicarb in Water and Foods, Including Bananas. Project Number: ALDICARB/01/01, 12971/01, 12971/02. Unpublished study prepared by Novigen Sciences, Inc. 168 p. 46427600 Bayer CropScience LP (2004) Submission of Exposure and Risk Data in Support of the Registration of Carbamate Products. Transmittal of 1 Study. 4642760 1 Pandian, M. (2004) USD A Pesticide Data Program (PDF) Monitoring Data for Carbamate Cumulative Risk Assessment. Project Number: DAL 1 19/04. Unpublished study prepared by Infoscientific.Com, Inc. 86 p. 46466400 Bayer CropScience LP (2005) Submission of Residue Data in Support of the Reregistration of the Aldicarb Containing Product Temik Brand Aldicarb Pesticide. Transmittal of 1 Study. 46466401 Movassaghi, S.; Daussin, S.; Hanzas, J. (2005) Surface Water Monitoring for Residues of Aldicarb in High Use Areas in the United States: Final Study Report. Project Number: OOT30605, B004894. Unpublished study prepared by Bayer CropScience LP, Bayer Corp. and Agvise Inc. 1553 p. 46542800 Bayer CropScience LP (2005) Submission of Exposure and Risk Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46340600 46340601 Page 178 of 191 ------- 46542802 Hodges, L. (2005) Review of the Preliminary Environmental Fate and Ecological Effects (EFED) Risk Assessment for the Aldicarb Reregistration Eligibility Decision. Unpublished study prepared by Bayer CropScience LP. 66 p. 46571300 U.S. Environmental Protection Agency (2005) Submission of Toxicity Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46571301 U.S. Department of Health, Education, and Welfare, National Cancer Institute (1979) Bioassay of Aldicarb for Possible Carcinogenicity: NCI/CG/TR/136. Bethesda, MD: US National Institutes of Health. 119 p. NIH Publication no. 79-1391. 46579100 Bayer CropScience LP (2005) Submission of Exposure and Risk Data in Support of the Reregistration of Aldicarb and Isoproturon. Transmittal of 2 Studies. 46579101 Urtizberea, M. (1999) Worker Loader and Applicator Exposure Study During Application in Citrus Plantation with Temik 10G. Project Number: R009475, SA/98148. Unpublished study prepared by Bayer Cropscience. 175 p. 46613000 Bayer CropScience LP (2005) Submission of Exposure and Risk Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46613001 Tobia, A. (2005) Bayer Cropscience Response to EPA Request for Clarification Concerning the 1992 Wyld et al. Aldicarb Study with Human Volunteers. Project Number: BCS/003237/1, 003237. Unpublished study prepared by Bayer CropScience LP. 59 p. 46618000 U.S. Environmental Protection Agency (2005) Submission of Toxicity Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46618001 U.S. Environmental Protection Agency (1997) NHEERL/EPA Study with Aldicarb: Initial Measurements of ChE Activity in Rat Brain (AE1). Unpublished study. 2 p. 46627800 Bayer CropScience (2005) Submission of Exposure, Risk and Safety Data in Support of the Reregistration of Aldicarb. Transmittal of 3 Studies. 46627801 Hodges, L. (2005) Response to the Phase 3 Environmental Fate and Ecological Effects (EFED) Risk Assessment for the Aldicarb Reregistration Eligibility Decision. Unpublished study prepared by Bayer CropScience LP. 70 p. 46627802 Hall, L.; Shaw, R.; Fish, I; et. al. (2005) Temik 15G Brand Aldicarb: Product Usage and Methods of Application: Revised Version. Project Number: G201361. Unpublished study prepared by Bayer CropScience LP. 34 p. 46627803 Hovis, A. (2005) Temik Brand Aldicarb Pesticide Product Stewardship Review. Project Number: AH81005. Unpublished study prepared by Bayer CropScience LP. 13 p. 46638100 Bayer CropScience LP (2005) Submission of Risk and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46638101 Barraj, L.; Daniels, C. (2004) Drinking Water Consumption Survey. Project Number: 04/01, 8/000/BOFO/0904/0001. Unpublished study prepared by Exponent. 40 p. 46655400 Bayer CropScience LP (2005) Submission of Exposure and Risk Data in Support of the Reregistration of Aldicarb. Transmittal of 2 Studies. Page 179 of 191 ------- 46655401 Moore, D.; Thompson, R.; Purbrick, S. (2005) Problem Formulation for the Refined Aquatic Risk Assessment of Aldicarb. Project Number: 201373, 88380. Unpublished study prepared by Cantox Environmental Inc. 31 p. 46655402 Moore, D.; Purbrick, S.; Thompson, R. (2005) Problem Formulation for the Refined Wildlife Risk Assessment of Aldicarb. Project Number: 201374, 88380. Unpublished study prepared by Cantox Environmental Inc. 37 p. 46765100 Union Carbide Agricultural Products Co. (1980) Submission of Toxicity Data in Support of the Registration of Temik 15G Aldicarb Pesticide. Transmittal of 2 Studies. 46765101 Godek, E.; Dolak, M.; Matthews, R.; et. al. (1980) Ames Salmonella/Microsome Plate Test: Aldicarb Sulfoxide. Project Number: PH/301/UC/002/80. Unpublished study prepared by Pharmakon Laboratories. 14 p. 46765102 Godek, E.; Dolak, M.; Matthews, R.; et. al. (1980) Ames Salmonella/Microsome Plate Test: Aldicarb Sulfone. Project Number: PH/301/UC/003/80. Unpublished study prepared by Pharmakon Laboratories. 14 p. 46792600 Bayer CropScience LP (2006) Submission of Pesticide Use in Support of the Reregistration of the Aldicarb Containing Product Temik 15G. Transmittal of 1 Study. 46792601 Hall, L. (2006) Temik Brand 15G Aldicab Pesticide Crop and Geographical Usage Information (A Reference Provided for an Endangered Species Assessment of Aldicarb). Project Number: G201481. Unpublished study prepared by Bayer Cropscience LP. 76 p. 46793700 Bayer CropScience LP (2006) Submission of Environmental Fate Data in Support of the Reregistration of the Aldicarb Containing Product Temik Brand 15G Aldicarb Pesticide. Transmittal of 5 Studies. 46793701 Jones, R.; Ramanarayanan, T. (2006) Temik BrandlSG Aldicarb Pesticide: Summary of Five Retrospective Ground Water Monitoring Studies Conducted for Aldicarb and its Metabolites in the Pacific Northwest, California, Texas, Mississippi Delta and the Southeast Regions fo the United States in 2005. Project Number: RAVY010. Unpublished study prepared by Bayer Corp. 27 p. 46793702 Freeseman, P.; Jones, R.; Lee, R.; et. al. (2006) A Retrospective Groundwater Monitoring Study for Aldicarb and its Metabolites in the Pacific Nothwest: (Temik Brand 15G Aldicarb). Project Number: RAAVY005, YT/01/01, B003390. Unpublished study prepared by Bayer Corp. and LFR Levine-Fricke, Inc. 1033 p. 46793704 Mosier, D.; Jones, R.; Nandihalli, U.; et. al. (2006) A Retrospective Groundwater Monitoring Study for Aldicarb and its Metabolites in Texas: (Temik Brand 15G Aldicarb Pesticide). Project Number: RAAVY007, YT/01/01, B003390. Unpublished study prepared by Bayer Corp. and LFR Levine-Fricke, Inc. 749 p. 46793705 Wyatt, D.; Jones, R.; Nandihalli, U.; et. al. (2006) A Retrospective Groundwater Monitoring Study for Aldicarb and its Metabolites in the Mississippi Delta Region: (Temik Brand 15G Aldicarb Pesticide). Project Number: RAAVY008, YT/01/01, B003390. Unpublished study prepared by Bayer Corp. and LFR Levine-Fricke, Inc. 690 p. 46793706 Lee, R.; Jones, R.; Wyatt, D.; et. al. (2006) A Retrospective Groundwater Monitoring Study for Aldicarb and its Metabolites in the Southeastern United States. Project Number: RAAVY009, YT/01/01, B003390. Unpublished study prepared by Bayer Corp. and LFR Levine-Fricke, Inc. 2955 p. Page 180 of 191 ------- 46796100 Bayer CropScience LP (2006) Submission of Toxicity, Exposure and Risk Data in Support of the Reregistration of the Aldicarb Containing Product Temik Brand 15G Aldicarb Pesticide. Transmittal of 3 Studies. 46796101 Ramanarayanan, T. (2006) Refined Aquatic Ecological Exposure Assessment for Total Carbamate Residues From Aldicarb. Project Number: MEAVY006. Unpublished study prepared by Bayer Corp. 75 p. 46796102 Moore, D.; Thompson, R.; Purbrick, S. (2006) Refined Aquatic Risk Assessment for Aldicarb. Project Number: 201482. Unpublished study prepared by Cantox Environmental Inc. 234 p. 46796103 Moore, D.; Purbrick, S.; Teed, R.; et. al. (2006) Refined Wildlife Risk Assessment for Aldicarb. Project Number: 201483, 88390. Unpublished study prepared by Cantox Environmental Inc. 493 p. 46796600 Bayer CropScience LP (2006) Submission of Exposure and Risk Data in Support of the Reregistration Aldicarb. Transmittal of 2 Studies. 46796601 Young, B.; Mihlan, G.; Lantz, I; et. al. (2006) CARES-compatible Dietary Minute Module (DMM) Version 2.2 Build 7.8.9 (3/14/06). Project Number: G201503. Unpublished study prepared by Syngenta Crop Protection, Inc. and Infoscientific.Com. 38 p. 46796602 Kelly, I.; Lantz, I; Mihlan, G.; et. al. (2006) CARES-compatible Dietary Minute Module (DMM) Version 2.2 Build 7.8.9 (3/14/2006): Technical Manual. Project Number: G201504. Unpublished study prepared by Syngenta Crop Protection, Inc. 27 p. 46819500 Bayer CropScience LP (2006) Submission of Environmental Fate Data in Support of the Reregistration of the Aldicarb Containing Product Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 46819501 Lenz, M.; Jones, R.; Wyatt, D.; et. al. (2006) A Retrospective Groundwater Monitoring Study for Aldicarb and Its Metabolites in California. Project Number: RAAVY006, 004/11333/00, YT/01/01. Unpublished study prepared by Bayer Corp. and LFR Levine-Fricke, Inc. 767 p. 46834000 Interregional Research Project No. 4 (2006) Submission of Fate Data in Support of the Registration of Citrus Fruits Group 10. Transmittal of 1 Study. 46834001 Chen, H. (2006) Crop Grouping Petition Citrus Fruits Group 10, Technical Amendment to 40 CFR 180.41 (c)(10) and 180.1 (h). Unpublished study prepared by Interregional Research Project No. 4 and U.S. Dept. of Agriculture. 303 p. 46857900 Interregional Research Project No 4 (2006) Submission of Residue Data. Transmittal of 1 Study. 46857901 Chen, H. (2006) Crop Grouping Petition Pome Fruit Group 11, Technical Amendment. Project Number: A/27200/16/06. Unpublished study prepared by Interregional Research Project No. 4. 390 p. 46873100 Bayer CropScience LP (2006) Submission of Exposure and Risk Data in Support of the Reregistration of Aldicarb Product Containing Temik Brand 15G Aldicarb Pesticide. Transmittal of 1 Study. 46873101 Best, L.; Brewer, L.; Klaine, S.; et. al. (2006) Refined Ecological Risk Assessment for Aldicarb Expert Peer Review Panel Process and Comments. Project Number: EPR/32306. Unpublished study prepared by Bayer CropScience LP. 10 p. Page 181 of 191 ------- 46891400 Bayer CropScience (2006) Submission of Risk and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 5 studies. 46891401 Tobia, A.; Blacker, A. (2006) Bayer CropScience's Assessment and Rebuttal of the Reference Dose as Proposed by EPA in the Health Effects Division Revised Preliminary Human Helath Risk Assessment for Aldicarb Issued on May 12, 2006. Project Number: G201557. Unpublished study prepared by Bayer Crop Science LP. 16 p. 46891402 Lantz, I; Young, B.; Jones, R.; *et. al. (2006) Aldicarb Acute Dietary Risk Assessment Including Food and Drinking Water Volume 1. Project Number: G201350. Unpublished study prepared by Bayer Crop Science LP. 219 p. 46891403 Kelly, I.; Lantz, I; Mihlan, G.; *et. al. (2006) Incorporating Rapid Reversibility into the Dietary Risk Assessment for Aldicarb. Project Number: G201550. Unpublished study prepared by Bayer Crop Science LP. 33 p. 46891405 Hall, L. (2006) The Benefits to Agriculture of Temik Brand 15G Aldicarb Pesticide. Project Number: G201529. 126 p. 46891406 Fischer, D.; Ramanarayanan, T.; Jones, R. (2006) Response to the EPA Environmental Risk Assessment for the Aldicarb Reregistration Eligibility Decision. Project Number: G201560. Unpublished study prepared by Bayer Crop Science LP. 23 p. 46898900 Bayer CropScience (2006) Submission of Efficacy Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 46898901 Blacker, A.; Jones, R.; Kelly, I.; et. al.; (2006) Aldicarb: Human Health Risk Assessment for Use on Currently Registered and Pending Registrations as of May 2006. Project Number: G201555. Unpublished study prepared by Bayer CropScience LP. 86 p. 47061700 Interregional Research Project NO.4. (2007) Submission of Residue Data in Support of the Petition for Tolerance of Stone Fruits Group. Transmittal of 1 Study. 47061701 Chen, H. Crop Grouping Petition-Stone Fruit Group 12, Technical Amendment To 40 CFR 180.41 (C) 12 And 180.1 (h). Project Number: 09896. Unpublished study prepared by Interregional Research Project No. 4. 304 p. 47124600 Bayer CropScience (2007) Submission of Risk and Exposure Data in Support of the Reregistration of Aldicarb. Transmittal of 1 Study. 47124601 Fisher, D.; Ramanarayanan, T.; Moore, D.; et. al.; (2007) Effects Determination for California Red-Legged Frog Potentially Exposed to Aldicarb. Project Number: 88380, 201692. Unpublished study prepared by Cantox Environmental, Inc. 138 p. 47164600 Croplife America (2007) Submission of Environmental Fate and Exposure and Risk Data in Support of the Preservation of the California Red Legged Frog. Transmittal of 2 Studies. 47164601 Moore, D.; Breton, R.; Rodney, S.; et. al.; (2007) Generic Problem Formulation for California Red-Legged Frog. Project Number: 89320, 05232007. Unpublished study prepared by Cantox Environmental Inc. 87 p. 47164602 Holmes, C.; Vamshi, R. (2007) Data and Methodology Used for Spatial Analysis of California Red Legged Frog Observations and Proximate Land Cover Characteristics. Project Number: 3152007, WEI/252/03. Unpublished study prepared by Waterborne Environmental, Inc. (WEI). 19 p. Page 182 of 191 ------- Appendix E. Generic Data Call-In (GDCI) Note that a complete generic DCI, with all pertinent instructions, will be sent to registrants under separate cover. Page 183 of 191 ------- Appendix F. Product-Specific Data Call-In (PDCI) Note that a complete product-specific DCI, with all pertinent instructions, will be sent to registrants under separate cover. Page 184 of 191 ------- Appendix G. EPA's Batching of Aldicarb Products for Meeting Data Requirements for Reregistration In an effort to reduce the time, resources and number of animals needed to fulfill the acute toxicity data requirements for reregi strati on of products containing ALDICARB as the active ingredient, the Agency has batched products which can be considered similar for purposes of acute toxicity. Factors considered in the sorting process include each product's active and inert ingredients (identity, percent composition and biological activity), type of formulation (e.g., emulsifiable concentrate, aerosol, wettable powder, granular, etc.), and labeling (e.g., signal word, use classification, precautionary labeling, etc.). Note that the Agency is not describing batched products as "substantially similar" since some products within a batch may not be considered chemically similar or have identical use patterns. Using available information, batching has been accomplished by the process described in the preceding paragraph. Notwith-standing the batching process, the Agency reserves the right to require, at any time, acute toxicity data for an individual product should the need arise. Registrants of products within a batch may choose to cooperatively generate, submit or cite a single battery of six acute toxicological studies to represent all the products within that batch. It is the registrants' option to participate in the process with all other registrants, only some of the other registrants, or only their own products within a batch, or to generate all the required acute toxicological studies for each of their own products. If a registrant chooses to generate the data for a batch, he/she must use one of the products within the batch as the test material. If a registrant chooses to rely upon previously submitted acute toxicity data, he/she may do so provided that the data base is complete and valid by today's standards (see acceptance criteria attached), the formulation tested is considered by EPA to be similar for acute toxicity, and the formulation has not been significantly altered since submission and acceptance of the acute toxicity data. Regardless of whether new data is generated or existing data is referenced, registrants must clearly identify the test material by EPA Registration Number. If more than one confidential statement of formula (CSF) exists for a product, the registrant must indicate the formulation actually tested by identifying the corresponding CSF. In deciding how to meet the product specific data requirements, registrants must follow the directions given in the Data Call-In Notice and its attachments appended to the RED. The DCI Notice contains two response forms which are to be completed and submitted to the Agency within 90 days of receipt. The first form, "Data Call-In Response," asks whether the registrant will meet the data requirements for each product. The second form, "Requirements Status and Registrant's Response," lists the product specific data required for each product, including the standard six acute toxicity tests. A registrant who wishes to participate in a batch must decide whether he/she will provide the data or depend on someone else to do so. If a registrant supplies the data to support a batch of products, he/she must select one of the following options: Developing Data Page 185 of 191 ------- (Option 1), Submitting an Existing Study (Option 4), Upgrading an Existing Study (Option 5) or Citing an Existing Study (Option 6). If a registrant depends on another's data, he/she must choose among: Cost Sharing (Option 2), Offers to Cost Share (Option 3) or Citing an Existing Study (Option 6). If a registrant does not want to participate in a batch, the choices are Options 1, 4, 5 or 6. However, a registrant should know that choosing not to participate in a batch does not preclude other registrants in the batch from citing his/her studies and offering to cost share (Option 3) those studies. Six products were found which contain Aldicarb as the active ingredient. These products have been placed into two batches in accordance with the active and inert ingredients and type of formulation. Batching Instructions: NOTE: The technical acute toxicity values included in this document are for informational purposes only. The data supporting these values may or may not meet the current acceptance criteria. Batch 1 EPA Reg. No. 264-330 264-417 264-426 264-523 Percent Active Ingredient 15.0 15.0 15.0 15.0 Batch 2 EPA Reg. No. 264-322 264-331 Percent Active Ingredient 10.0 10.0 Page 186 of 191 ------- Appendix H. List of Available Related Documents and Electronically Available Forms Pesticide Registration Forms are available at the following EPA internet site: http://www.epa.gov/opprd001/fortns/. Pesticide Registration Forms (These forms are in PDF format and require the Acrobat reader) Instructions: 1. Print out and complete the forms. (Note: Form numbers that are bolded can be filled out on your computer then printed.) 2. The completed form(s) should be submitted in hardcopy in accord with the existing policy. 3. Mail the forms, along with any additional documents necessary to comply with EPA regulations covering your request, to the following address for the Document Processing Desk: Document Processing Desk (distribution code)* Office of Pesticide Programs (7504P) Environmental Protection Agency 1200 Pennsylvania Ave, NW Washington, DC 20460-0001 * Distribution Codes are as follows: (APPL) Application for product registration (AMEND) Amendment to existing registration (CAN) Voluntary Cancellation (EUP) Experimental Use Permit (DIST) Supplemental Distributor Registration (SLN) Special Local Need (NEWCO) Request for new company number (NOTIF) Notification (PETN) Petition for Tolerance (XFER) Product Transfer DO NOT fax or e-mail any form containing "Confidential Business Information" or "Sensitive Information." If you have any problems accessing these forms, please contact Nicole Williams at (703) 308-5551 or by e-mail at williams.mcole@epamail.epa.gov. If you want these forms mailed or faxed to you, please contact Lois White, white.lois@epa.gov or Floyd Gayles, gayles.floyd@epa.gov. If you have any questions concerning how to complete these forms, please contact OPP's ombudsperson for conventional pesticide products: Linda Arlington, (703) 305-5446 Page 187 of 191 ------- The following Agency Pesticide Registration Forms are currently available via the Internet at the following locations: 8570-1 8570-4 8570-5 8570-17 8570-25 8570-27 8570-28 8570-30 8570-32 8570-34 8570-35 8570-36 8570-37 Application for Pesticide Registration/ Amendment Confidential Statement of Formula Notice of Supplemental Registration of Distribution of a Registered Pesticide Product Application for an Experimental Use Permit Application for/Notification of State Registration of a Pesticide To Meet a Special Local Need Formulator's Exemption Statement Certification of Compliance with Data Gap Procedures Pesticide Registration Maintenance Fee Filing Certification of Attempt to Enter into an Agreement with other Registrants for Development of Data Certification with Respect to Citations of Data (in PR Notice 98-5) Data Matrix (in PR Notice 98-5) Summary of the Physical/Chemical Properties (in PR Notice 98-1) Self-Certification Statement for the Physical/Chemical Properties (in PR Notice 98-1) http://www.epa.sov/opprd001/forms/8570-l.pdf http://www.epa.sov/opprd001/forms/8570-4.pdf http://www.epa.sov/opprd001/forms/8570-5.pdf http://www.epa.sov/opprd001/forms/8570-17.pdf http://www.epa.sov/opprd001/forms/8570-25.pdf http://www.epa.sov/opprd001/forms/8570-27.pdf http://www.epa.sov/opprd001/forms/8570-28.pdf http://www.epa.sov/opprd001/forms/8570-30.pdf http://www.epa.sov/opprd001/forms/8570-32.pdf http://www.epa.sov/opppmsdl/PR Notices/pr98- 5.pdf http://www.epa.sov/opppmsdl/PR Notices/pr98- 5.pdf http://www.epa.sov/opppmsdl/PR Notices/pr98- l.pdf http://www.epa.sov/opppmsdl/PR Notices/pr98- l.pdf Page 188 of 191 ------- Pesticide Registration Kit http://www.epa.gov/pesticides/registrationkit/ Dear Registrant: For your convenience, we have assembled an on-line registration kit which contains the following pertinent forms and information needed to register a pesticide product with the U.S. Environmental Protection Agency's Office of Pesticide Programs (OPP): 1. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Federal Food, Drug and Cosmetic Act (FFDCA) as Amended by the Food Quality Protection Act (FQPA) of 1996. 2. Pesticide Registration (PR) Notices a. 83-3 Label Improvement Program-Storage and Disposal Statements b. 84-1 Clarification of Label Improvement Program c. 86-5 Standard Format for Data Submitted under FIFRA d. 87-1 Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation) e. 87-6 Inert Ingredients in Pesticide Products Policy Statement f. 90-1 Inert Ingredients in Pesticide Products; Revised Policy Statement g. 95-2 Notifications, Non-notifications, and Minor Formulation Amendments h. 98-1 Self Certification of Product Chemistry Data with Attachments (This document is in PDF format and requires the Acrobat reader.) Other PR Notices can be found at http://www.epa.gov/opppmsdI/PR Notices. 3. Pesticide Product Registration Application Forms (These forms are in PDF format and will require the Acrobat reader.) a. EPA Form No. 8570-1, Application for Pesticide Registration/Amendment b. EPA Form No. 8570-4, Confidential Statement of Formula c. EPA Form No. 8570-27, Formulator's Exemption Statement d. EPA Form No. 8570-34, Certification with Respect to Citations of Data e. EPA Form No. 8570-35, Data Matrix 4. General Pesticide Information (Some of these forms are in PDF format and will require the Acrobat reader.) a. Registration Division Personnel Contact List b. Biopesticides and Pollution Prevention Division (BPPD) Contacts c. Antimicrobials Division Organizational Structure/Contact List d. 53 F.R. 15952, Pesticide Registration Procedures; Pesticide Data Requirements (PDF format) e. 40 CFR Part 156, Labeling Requirements for Pesticides and Devices (PDF format) f. 40 CFR Part 158, Data Requirements for Registration (PDF format) g. 50 F.R. 48833, Disclosure of Reviews of Pesticide Data (November 27, 1985) Page 189 of 191 ------- Before submitting your application for registration, you may wish to consult some additional sources of information. These include: 1. The Office of Pesticide Programs' Web Site 2. The booklet "General Information on Applying for Registration of Pesticides in the United States", PB92-221811, available through the National Technical Information Service (NTIS) at the following address: National Technical Information Service (NTIS) 5285 Port Royal Road Springfield, VA 22161 The telephone number for NTIS is (703) 605-6000. Please note that EPA is currently in the process of updating this booklet to reflect the changes in the registration program resulting from the passage of the FQPA and the reorganization of the Office of Pesticide Programs. We anticipate that this publication will become available during the Fall of 1998. 3. The National Pesticide Information Retrieval System (NPIRS) of Purdue University's Center for Environmental and Regulatory Information Systems. This service does charge a fee for subscriptions and custom searches. You can contact NPIRS by telephone at (765) 494-6614 or through their website. 4. The National Pesticide Telecommunications Network (NPTN) can provide information on active ingredients, uses, toxicology, and chemistry of pesticides. You can contact NPTN by telephone at (800) 858-7378 or through their website: http://npic.orst.edu The Agency will return a notice of receipt of an application for registration or amended registration, experimental use permit, or amendment to a petition if the applicant or petitioner encloses with his submission a stamped, self-addressed postcard. The postcard must contain the following entries to be completed by OPP: • Date of receipt • EPA identifying number • Product Manager assignment Other identifying information may be included by the applicant to link the acknowledgment of receipt to the specific application submitted. EPA will stamp the date of receipt and provide the EPA identifying File Symbol or petition number for the new submission. The identifying number should be used whenever you contact the Agency concerning an application for registration, experimental use permit, or tolerance petition. Page 190 of 191 ------- To assist us in ensuring that all data you have submitted for the chemical are properly coded and assigned to your company, please include a list of all synonyms, common and trade names, company experimental codes, and other names which identify the chemical (including "blind" codes used when a sample was submitted for testing by commercial or academic facilities). Please provide a CAS number if one has been assigned. Page 191 of 191 ------- |