United States
                              Envi?*nn»mtal»ProtectK»n
                              Agsney
Chemical Coordination Staff
Office of Pesticides and Toxic Substances
Washington  DC
EPA 950-R-83-005

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                  UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
                              WASHINGTON, D.C.  20460
•
§
MEMORANDUM

TO:       Assistant Administrators
          Regional Administrators
          AA  Budget Officers

SUBJECT:  Agency  Extramural Activity  Report  (EAR)  for
          Toxics-Related Projects,  Supplement  to Volume  II,
          Issue 2

     Attached  is  a supplement  to Volume  II,  Issue  2  of the
Extramural Activity Report  (EAR) prepared  by the Chemical
Coordination  Staff (CCS) of the Office of  Pesticides and Toxic
Substances.   It includes descriptions of toxics-related  projects
being undertaken  by the Office of Research and Development
which have been modified (including new  tasks  and  work assign-
ments) under  existing contracts, in addition to, any new grants,
cooperative agreements, or  interagency agreements  not included
in the two previous (January and May) issues of the  EAR*

     To facilitate use of the EAR,  the projects have been
indexed, where possible,, by chemical, industry and environmental
media.  These  indices are listed at the end  of the document.

     CCS will  continue to maintain  a  log of  the names and phone
numbers for the project officers? or  appropriate contacts for
each project to ensure that only legitimate  EPA users are put
in touch with  the project/program office as  well as  to track
the utilization of the EAR.
     If you
the project
please call
In addition
Centers has
For information on
Richard Marland in
                  have  any  questions,  suggestions,  or want  to contact
                  officer for  any  of  the  projects  listed in the EAR,
                  Joanne LaBaw or  Arnie Edelman  of  CCS at 382-3395.
                  to  the EAR,  the  Office  of  Research Grants and
                  information  available on FY  '83  research  grants.
                         these latter projects,  contact
                         ORD  (382-5737).             •„<:.
      )Howa-rd M. Messner
      Assistant Administrator
        for Administration
                                                        ;^«WJCVW
                                   Don R. Clay
                                   Assistant Administrator
                                     for Pesticides and
                                     Toxic Substances
      Attachment

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                                      Acknowledgement









The Chemical Coordination Staff of the Office of Pesticides and Toxic Substances wishes to




express  its appreciation  to  the  EPA  project managers,  contract officers,  and  program




budget officials, the Grants Administration Division and the Office of Research Grants and




Centers, who assisted in the  development of this document by providing contract and grant




information  and the  timely  review  of  draft descriptions.   Without  their enthusiastic




cooperation, production of this document would not have been possible.
                                                                  Walter W. Kovalick, Jr.
Information  concerning the  project officers  names and  phone number  for  these contract




efforts may  be obtained  from  Joanne LaBaw (382-3395) or  Arnie  Edleman (382-2249)  of the




Chemical Coordination staff.

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                                        TARLF OF  CONTENTS










Literature Searches	1




Fate and Transport/Materials Balances	. .2




Health/Environmental Effects	„	„	6




Health. Effects	7




Environmental Effects	17





Exposure.	21




Risk	23




Industrial Studies	24




Economic Studies	26




    o   Cost-Benefit Studies	30




Treatment Technology /Development Evaluation	„	33




Waste Management/Resource Recovery	38




Emergency Response.	„	44




Policy Studies/Regulatory Control Options.	.47




Methodology  Development/Validation.	„	.50




     o   Chemical Analyses.	=>	.50




     o   Treatment Processes and Monitoring.	51




     o   Health  and Environmental Studies	.52

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Statistical Analyses.	......................53




Modeling.	.54




Data Base Development.	................................55




Sampling Analysis and Monitoring.	...........................56




    o   General.,.,....»,....	.................................56




    o   Chemical Analyses - Special Topics,	..,.57




    o   Environmental Monitoring.	..............................58




Index	...................61




    o   Chemical.	*	.61




    o   Media. ..............................	.	......63




    o   Industry.	64

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LITERATURE SEARCHES
Title
Office/Divis ion
Description
Data Collection
ORD/Office of Health  and
Environmental Assessment
This  incremental   funding   action  will  provide
literature   searches   and  acquisitions   of  key
articles,  summarization and  evaluation  of data.
In   addition,    this    contract   will   prepare
assessments  to  substantiate reportable 'quantities
under  the  comprehensive  Environmental  Response
Corporation and Liability Act (CERCLA).

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FATE AMD TRANSPORT/MATERIALS BALANCES
Title
Office/Division
Potential for
Biotransformation of Toxic
Chemicals Defined by a
Molecular Probe
Grant
Sequential/Competitive
Reactions in Catalytic
Oxidation of
Model Chlorinated
Hydrocarbons
Grant
Mechanism of adsorption of
Organic Chemicals on Soils
During Groundwater
Pollutant Movement
Cooperative Agreement
                                                                      Description
She purpose of this grant is to develop and test a
new method that can be used to predict the fate of
specific  synthetic   chemicals   which  enter  the
environment.     cloning  genes  which  code  for  a
specific structural activity  group of xenobiotics
will be used  as  a "reagent™ or probe for directly
enumerating bacteria  which possess  the synthetic
chemical metabolizing enzymes„
A  recycle  reactor   will   measure  the  rate  of
oxidation  of  pairs  of  potentially  interacting
model chlorinated  hydrocarbons.   Inlet and outlet
concentrations   will    be   measured    by   gas
chromatography.  Kinetic  rate expressions will be
developed by standard regression techniques,

(Chemicals:  Chlorinated hydrocarbons)
This  cooperative  agreement  will  provide  for  an
investigation   of  the   two-step  mechanism   of
adsorption  of  non-ionic  organic  chemicals  from
water on soils.
                                                                      (Chemicals:  Organics)
                                                                      (Media:  Groundwater)

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FATE AND TRANSPORT/MATERIALS BALANCES
Title
Office/Division
Potential for
Biotransformation of Toxic
Chemicals Defined by a
Molecular Probe
Grant
Sequential/Competitive
Reactions in Catalytic
Oxidation of
Model Chlorinated
Hydrocarbons
Grant
Mechanism of Adsorption of
Organic Chemicals on Soils
During Groundwater
Pollutant Movement
Cooperative Agreement
                                                                      Description
The purpose of this grant is to develop and test a
new method that can be used to predict the fate of
specific  synthetic   chemicals   which  enter  the
environment.     Cloning  genes  which  code  for  a
specific structural activity  group of xenobiotics
will be used  as  a "reagent" or probe for directly
enumerating bacteria  which possess  the synthetic
chemical metabolizing enzymes.
A  recycle  reactor   will   measure  the  rate  of
oxidation  of  pairs  of  potentially  interacting
model chlorinated  hydrocarbons.   Inlet and outlet
concentrations   will    be   measured    by   gas
chromatography.  Kinetic  rate expressions will be
developed by standard regression techniques,

(Chemicals;  Chlorinated hydrocarbons)
This  cooperative  agreement  will  provide  for  an
investigation   of  the   two-step  mechanism   of
adsorption  of  non-ionic  organic  chemicals  from
water on soils.
                                                                      (Chemicals:  Organics)
                                                                      (Media:  Groundwater}

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FATE AND TRANSPORT/MATERIALS BALANCES
Title
Office/Division
Evaluation of Chemical
Reaction Mechanisms for
Photochemical Air
Pollution
Cooperative Agreement
Reactions of Ozone  with
Organics in Aqueous
Solutions
Cooperative  Agreement
Natural  Hydrocarbons in
Photochemical Air
Pollution.
 Assistance Amendment
Description
The  objectives  of  this  project  are:     (1)  to
prepare   a   State-of-the-Science   document   on
available chemical mechanisms;  (2)  test the effect
of  using  different  chemical  mechanisms  on  the
predications of ozone/precursor concentrations and
on EKMA control requirement estimates; and  (33 use
available aerometric air quality  data to determine
the accuracy of predictions.

(Media:  Air)
The  .objective  of   this   project  is   to  provide
information  on  aqueous   phase   ozone/hydrocarbon
reactions     (reaction    rates    and    product
identification).    The reactions  studied  are to
lead  to information on  organic aerosol formation
rates and lifetimes in the trophosphere.

(Chemicals:  Organics)
The purpose  of this study is  to  determine  natural
hydrocarbon  emission rates using a tracer  release
dispersion procedure.

(Chemicals:  Hydrocarbons)

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FATE AND TRANSPORT/MATERIALS BALANCES
Title
Office/Division
Pollutant Sorption to
Soils/Sediments in
Organic/Aqueous Solvent
Systems
Cooperative Agreement
Microbial Transport and
Pate of Synthetic Dyes
Cooperative Agreement
Experimental and
Theoretical Studies of
Contaminant Dispersion in
Ground Water
Cooperative Agreement
                                                                      Description
The  project   seeks   to  develop  procedures  for
predicting  sorption  as  a  function  of  solvent
composition.    A  theoretical   framework  will  be
developed  for describing  sorption  in nonaqueous
media.    Emphasis  will  be  placed  on  a  prior
prediction  utilizing  readily   available  physical
properties of system constitutents.

(Chemicals;  Solvents)
(Media:  Land)
For this  project,  field samples of microorganisms
will be  brought into  the laboratory  for testing
sorption and transformation of ten synthetic dyes.

(Chemicals;  Synthetic dyes)
The  purpose   of  this  project   is   to  advance
understanding of  contaminant dispersion in ground
water  through performance  of a  large,  detailed,
three-dimensional  field   study   of  hydrodynamic
dispersion coupled with  extensive analysis of the
results.

(Media:  Groundwater)

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FATE AND TRANSPORT/MATERIALS BALANCES
Title
Office/Division
                                Cooperative Agreement
Work on Long-Range
Transport Model
Uncertainty
Description
                                       This project will examine current understanding of
                                       the physical processes responsible  for  long-range
                                       transport    and    deposition    of    atmospheric
                                       pollutants.

                                       (Media:   Air)

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HEALTH/EMVIROHMENAL EFFECTS
Title
Of £ ice/Di vlgion
Description
.Geographic  Integrated
Environmental  Management
Study
'OPRM/Office  of Policy Anaylsis
This project  will involve the further development
and application of methodolgies designed to assist
in  the  understanding  of  potential  health  and
environmental impacts from multi-media exposure to
pollutants  and  potential-mechanisms  for  limiting
or  controlling specified pollutants  in  a  cost-
effective way.  These- methodolgies will be applied
in a specified geographical context.

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HEALTH EFFECTS
Title
Office/Division
Neurotoxicity of Low Level
Prenatal Exposure  to
Hypotoxic Agents
Grant
Evaluation  of  the
.Reproductive Effects of
Chlorine  Dioxide,
Chloramine  and Chlorine
Administration in the
Drinking  Water of Rats
Cooperative Agreement
 Pharmacokinetics and
 Metabolism of
 Chlorophenols in the Rat
 Grant
Description
The purpose  of this  study is to  obtain a better
understanding  of  the prenatal  neurotoxic effects
of hypoxic agents such as carbon monoxide.
The major objective of  this project is to evaluate
the reproductive  effects of ingestion of drinking
water disinfectants in both males and females.

(Chemicals;  Chlorine dioxide, chloramine,
             chlorine)
(Media:  Drinking water)
The  purpose  of this project is to  investigate  the
metabolism  of  2-  and 4-  chlorophenol  and  2,4-
dichlorophenol       and      also       investigate
pharmacokinetic pathways.

(Chemicals;  2-Chlorophenol, 4-chlorophenol,
             2,4-dichlorophenol)

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HEALTH EFFECTS
Title
Office/Division
Pharmacokinetics and
Chemical Toxicity of
Uranium-238 in Drinking
Water
Assistance Amendment
Effects of Toxic
Substances on Memory
Grant
Trihalomethanes in
Drinking Water and Colon
Cancer
Grant
                                                                       Description
This project will evaluate  the pharmacokinetics in
major  organs  and  chemical  toxicity to  bone and
kidney.

(Chemical:  Uranium-238)
(Media:  Drinking water)
Using  rats,  this study  will  research the effects
of  exposure  to  toxic  substances   and  reference
drugs   on   memory,    acquisition,    and   general
performance.  In addition  to providing useful data
on particular  toxic substances,  the research has
the  more  general  objective  of  establishing the
feasibility   and    importance   for   behavioral
toxicology   of   determining   effects  of   toxic
substances on memory and acquisition.
This  grant will provide  a case  control  study to
test    the    hypothesis     that    exposure    to
trihalomethanes  in   drinking   water   confers  a
significant risk of colon cancer.

(Chemicals:  Trihalomethanes)
(Media:  Drinking water)

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HEALTH EFFECTS
Title
Office/Division
Test of a Highly Sensitive
Drosophila Assay for
Chemical Induced
Chromosome Breakage
Grant
'Effect of  Polychlorinated
Biphenyls  (PCB's)  on Early
Developmental  Events
During Sea Urchin
Embryogenesis     ' "
 Grant
 Development and
 Application of an In vitro
 Tumor Promoter Assay
 Grant
                                                                      Description
The purpose  of this grant  is to  develop a quick
sensitive test to detect  carcinogens  in the total
environment.
The purpose  of  this grant is to determine effects
of  PCB's  on early- development of  sea  urchin egg
fertilization   and  to  study  post-fertilization
development  through analysis of nucleic  acid and
protein synthesis.

(Chemicals:  Polychlorinated biphenyls)
This project  will  develop a quantitative assay to
detect chemicals that could be tumor promoters.

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HEALTH EFFECTS
Title
Off ice/Divi s i on
Description
Collaborative Research in
Health Effects of
Environmental Pollutants
Assistance Amendment
This  project   will   establish  a  mechanism  for
scientific  exchange  and  interaction  between the
research  efforts  at the  Center  for Environmental
Health  and  Medical  Sciences  and  the  clinical
research activities of the Health Effects Research
Laboratory to include mutual research projects and
training programs.
Flow Cytometry of Sperm as
a Dosimeter of Toxic
Chemical Health Hazards
Grant
In  this  project,  sperm  and  lymphocyte cells will
be  exposed  to various  toxic chemicals  and their
effects  measured   by  flow  cytometry.     Other
biochemical and  morphological parameters  will be
measured  simultaneously  to  better   explain  the
overall processess involved.
The Central Nervous
System:  Molecular and
Cellular Factors
Influencing Neural
Development
Grant
This  grant  will  provide  for  a  conference  to
convene distinguished  scientists from  around the
world to study a variety of scientific topics.
                                                         1 0

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Title
Office/Division
Description
Metabolism of Chemical
Carcinogens in Human and
Animal Tissues
Cooperative Agreement
This project  will investigate  the  feasibility of
using organ culture for assessment of human health
risk due to exposure to carcinogenic chemicals.
Texas Pesticides Hazard
Assessment Project
Cooperative Agreement
This project  will develop  scientific  data on  the
magnitude and effects  of pesticides on the health
of the U.S. population.

(Chemicals:  Pesticides)
Inhalation Toxicology of
Formaldehyde-Containing
Air Pollutants
Grant
This  project will  evaluate  short-term  toxic  and
irritant   effects   of   combined   photochemical
pollutants  including  formaldehyde,  particulates,
and ozone exposure during exercise.

(Chemical;  Formaldehyde, ozone, photochemical
            oxidants)
(Media:  Air)
                                                         1 1

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Title
Office/Division
Description
Cohort Studies of Oxidant
Exposure
Cooperative Agreement
The  purpose  of  this project  is to  determine if
long-term exposure  to photochemical  oxidants and
other  secondary  pollutants  characteristic  of the
Southern California  Mr  Basin  is  associated with
the   initiation   or   promotion   of  respiratory
impairment or chronic respiratory disease.

(Chemicals;   Photochemical oxidants)
(Media:  Air)
An Evaluation of Neuron-
Specific Proteins as
Biochemical Indicators of
Neurotoxicity
Cooperative Agreement
This  research will  utilize  radioimmunoassays of
neuron—specific  proteins   and   assays  of  their
corresponding mRNAs as a measure of  the effects of
known and suspected neurotoxicants on  the neuronal
components  of  the developing  and  adult nervous
system.

Chemicals:  Neuron—specific proteins)
Lead Emissions and Lead
Blood Levels
 OPRM/Office  of  Policy Analysis
This  work  assignment will  collect,  critique,  and
in some cases reestimate background  information on
the  relationship between  lead  emissions  and  the
measured levels  of  lead in the blood of sensitive
populations.  This  information  will  be used  in  the
development   of   a   Regulatory  Impact   Analysis
(benefit/cost)  of  the ambient air  standard  for
lead emissions.

(Chemical:  Lead)
(Media:  Air)
                                                         1 2

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HEALTH EFFECTS
Title
Of fice/Pivision
Description
Estimation of Health
Impacts of Air Pollution:
Respiratory Disease in
Birmingham
OPRM/Office of  Policy Analysis
This work assignment will provide  three studies  to
help  estimate   the  benefits   of  reducing  air
pollution.    These include:    1}   a  time  series
analysis -of  the  relationship  between respiratory
disease and  fine  and  total  particulate matter  in
Birmingham; 2) a  time  series analysis  of mortality
and  total  partictiles; and  3}  a   cross-sectional
analysis  relating  certain   health   outcomes   to
exposure  to ozone using the 1979  Health Interview
Survey.                                    ;  .  . ._-^

(Media):  Air)
Assessment of  Hazardous
Air Pollutants Not on
EPA's Candidate List
 OPRM/Office of Policy Analysis.
This  work assignment  will  provide for the  review
of  lists -of known  air  pollutants.    From  these
lists,  potentially  hazardous   compounds   not  on
EPA's   "candidate   list"  •will  be  chosen   using
scientific•  judgement,   based   on   professional
experience.  The potential  health hazard and major
sources of each chosen compound will he evaluated.

(Media:  Air)
                                                          1 3

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HEALTH EFFECTS
Title
Office/Division
Description
Development of Superfund
Health Assessment Guidance
OPRM/Office of Policy Analysis
This   work  assignment   will  provide   for  the
preparation  of  documents  on  the  development of
health   assessments   mandated  by   the  National
Contingency Plan.   The major output  of this  task
will  be  a health  assessment  guidance manual  that
will  describe  in  detail  the  procedure  by which
exposure and toxicological  data  should be used in
the evaluation of  the  effect of Superfund response
actions  on the  surrounding population.   Guidance
specific  to  removal  and   remedial  actions,  and
preparation  of  case  studies  to  demonstrate  its
applicability will also be included.
S true tur e -Ac ti vi t y
Relationships
ORD/Office of Health and
Environmental Assessment
The  purpose of  this new contract is  to develop
techniques     for    using    structure-activity
relationships of chemicals  to predict toxicity and
carcinogenic potential  for use in rapid response
health hazard'assessments.
Technical Support for
Preparation of Criteria
and Health Assessment
Documents
ORD/Office of Health and
Environmental Assessment
This  incremental   funding  action  will  support
preparation and production of air .quality criteria
documents and health assessments,

(Media):  Air)
                                                         1 4

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HEALTH EFFECTS
Title
Office/Division
                                                                       Description
Document Technical Support
ORD/Office of Health and
Environmental Assessment
This   incremental   funding   action   will   give
technical  support  for  preparation  of  lead  air
quality  criteria documents  and  health assessment
documents.

(Chemical;  Le ad)
(Media:  Air)
Health Effects Document
ORD/Office  of  Health and
Environmental  Assessment
The  purpose of  this contract  modification  is  to
prepare  a document  -regarding  the  health effects
associated  with  exposure  to  either  criteria  or
hazardous pollutants.   This study will be used for
developing further regulatory strategy.          "'"

(Chemicals;  Hazardous pollutants)
Estimation of  Gonadal  Dose
Using Sister Chromatid'
Exchange and Alkylation
Studies in Germ  Cells  and
Somatic Cells  of Male  Mice-
ORD/Office  of  Health and
Environmental  Assessment
This  incremental  funding  action  is  to  improve
EPA's understanding  of the dosimetry approach  for
mutagenicity  risk assessments.   Emphasis will  be
-on the  relationship  between -alkylation to DNA  and
genetic damage,

(Chemical'(s);  Ethylene oxide)
Carcinogen Study
 ORD/Office of Health and
 Environmental Assessment
                                                          1 5
The  purpose  of this incremental funding action  is'
to give  pathology support for pathologist  consul-
tation and slide reviews on specific carcinogens.
This will aid  regulatory decision evaluation.

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HEALTH EFFECTS
Title
Office/Division
Description
Effective Human Dose of
Toxicants
ORD/Office of Health and
Environmental Assessment
The purpose of  this  incremental funding action is
to conduct  a  workshop on  estimation of effective
human dose of toxicants corresponding to dosage in
animal experiments.
                                                         1 6

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ENVIRONMENTAL EFFECTS
Title
Office/Division
                                                                       Description
Effects Assessment of
Selected Chemicals on
Estuarine and Marine
Organisms
Assistance Amendment
Objectives are  to  complete  a series  of toxicity
tests  with selected  pesticides  and  certain non-
target estuarine or marine animals.  The chemicals
to  be  used  will  include  fenthion  and  maled.
Static  and   flow-through   acute  tests  will  be
completed with Mysiodopsis  bohia.

(Chemicals:  Fenthion, maled)
(Media:  Water)
Mathematical Modeling of
Chemical-Structure
Relationships
Cooperative Agreement
The  objectives  of  this  project  are  to:     (1)
compile an aquatic toxicity data base?  (2) develop
computer   software   for   analysis   of  factors
influencing   aquatic   toxicity;    (3)   establish
quantitative   relationships   with   QSAR  methods
between  physical/chemical parameters  and  aquatic
toxicityj  (4)  develop   mathematical   models   for
statistical analysis; (5) apply structure-activity
for   predicting    fate    and   transport   model
parameters,

(Medias  Water)
Impact of  Ocean Waste
Disposal on  the Physiology
of Two Benthic Species
 Cooperative  Agreement
The  purpose  of this  project  is  to  develop  the
physiological  effects  indicators needed to assess
the  health  of  benthic  communities  impacted  by
ocean dumping operations,

(Media:  Water)
                                                            17

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ENVIRONMENTAL EFFECTS
Title
Office/Division
 Description
Aquatic Toxicity  Testing
and Criteria Document
Development
Assistance Amendment
The  objectives of  this  study  are  to  extend and
further  develop  the acute  and  chronic  toxicity
tests  for  solid  waste  extracts,  the   supporting
technical  information  for  the  ammonia  criteria
document, and  the comparative toxicology data base
to  be used  for  determining the  relationship of
species sensitivity to industrial chemicals,

{Chemical:  Ammonia)
(Media:  Water)
Aquatic Pollutant
Assessments and
Development of a Hazard
Prediction Technology by
Quantitative Structure-
Activity Relationships
Cooperative Agreement
The   objectives
determine   LCC
                  of  this   project  are  to   (T)
             '50  values   for   selected  organic
chemicals;  (2)  determine "no  effect"  levels with
embryo-larval   tests,   (3)    develop    structure-
activity    relationships    {OSAR)   for   aquatic
toxicity, and" (4)  determine blood/water partition
coefficients- of selected chemicals.

(Chemicals;  Organic chemicals)
(Media:Water)
Ecological impact of
Selected Pollutants on  the
Estuarine Ecosystem
Cooperative Agreement
The  general  objective  of  this  agreement -is--  to
support the University of Rhode  Island  in carrying
out  a cooperative- research  program "with".;'E]S:^T33-
accelerate    the   development    of    ecological
assessment methodologies.
                                                                                                                            -  ,,
                                                            1 8

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ENVIRONMENTAL EFFECTS
Title
Office/Division
 Description
Toxic and Sublethal
Effects of Waste Drilling
Muds and Certain Chromium
Compounds on Crustaceans
Assistance Amendment
This  project will  develop and  use a  variety of
toxicity   tests   for:      critical   life  stages;
molting, growth and fecundity; ultrastructure; and
cytotoxic  antimitotic,  teratologic  effects.   Test
organisms  arej     Mysidopsis   bahia,  pa'laemone tes
pugip, Penaeus agtecus, Acartia tonsa.

(Chemical;  Chromium compounds)
Development and  Evaluation
'of Community and Ecosystem
Level Toxicity Test
Cooperative Agreement
The  objectives  of   this  project   include:     1)
evaluation of  the  behavior of a naturally-derived
microcosm  test  system developed  by  Leffler,   as
influenced by  a wide range  of  toxic  substances,
(2) participation  in  a interlaboratory comparision
of an  artifically  assembled microcosm  test system
developed by Taub.
Development  of  Toxicity
Test Protocols  Using the
Marine  Red Alga Champia
Parvula
 Cooperative Agreement
This   project  will  verify  an  existing   static
toxicity  test using  the marine  red alga  Champia
parvula  to assess  chronic  effects  of  pollutants.
Organic  compounds .will  be  used  in verifying  the
test,  and a  test protocol will  be developed  for
use by OTS,

(Chemical:  Organics)
                                                            1 9

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ENVIRONMENTAL EFFECTS
Title
Office/Division
 Description
Environmental- Persistence
Data
ORD/Office of Health and
Environmental Assessment
The  purpose  of this  incremental  funding  is  to
collect  and  evaluate  environmental  persistence
data for all media including air.

(Mediar  Air)
                                                           20

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EXPOSURE
Title
Office/Division
Description
Man's Exposure to
Halogentated Organics  from
His Drinking Water
Cooperative Agreement
This   cooperative   agreement   wi-11   study   the
relationship between ingestion  of  drinking water
from a municipal chlorinated  supply  and subsequent
blood levels of halogenated organics in man.

(Chemicals;  Halogenated organics)
(Media;  Drinking water)
 South Carolina  Pesticide
 Hazard Assessment Program
Cooperative  Agreement
This  project will develop  scientific data on  the
magnitude and effects of  exposure  to  pesticides on
the health of the U.S. population.

(Chemicals:  Pesticides)
 Exposure  Assessments
 ORD/Office of Health and
 Environmental Assessment
The purpose  of this incremental funding action  is
to  do  a  .survey  of   literature  and  perform
calculations  to  provide  data  and estimates  for
exposure   assessments   related  to   listing   of
hazardous wastes and permitting disposal.

(Chemicals:?  Hazardous wastes)
                                                          21

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EXPOSURE
Title
Office/Division
Description
Exposure Profiles
ORD/Office of Health and
Environmental Assessment
This incremental  funding action will  do a survey
of literature  and performance of  calculations to
provide data  and estimates  for  exposure profiles
for  setting   priorities   among   hazardous  solid
wastes.

(Chemical(s):   Hazardous solid wastes)
Survey Method for
Estimating Exposure to
Chemicals
ORD/Office of Health and
Environmental Assessment
This  incremental  funding action  will  perform a
survey   of  methods   to  estimate   exposure  to
chemicals   from   landfills    by  suspension  of
contaminated dust particles in air.

(Media;  Mr)
Exposure Assessment
Guidelines
ORD/Office  of  Health  and
Environmental  Assessment
The purpose  of the  incremental  funding action is
to conduct a  review and an evaluation of exposure
assessment guidelines.
                                                         22

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RISK
Title
Office/Division
Description
Evaluation of Ground Water
Contamination Risks
Resulting Prom  Hazardous
Wastes Disposal
Cooperative Agreement
This  cooperative agreement  will  provide  methods
and data to predict concentrations of wastes that
escape  into  the  environment  from  disposal  of
hazardous wastes.

(Chemicalss  Hazardous wastes)
(Media;  Ground water)
Toxic Materials  Support
Documentation
 ORD/Office  of Health and
 Environmental Assessment
This   incremental   funding  action  will  prepare
supporting     documentation    for    hazard/risk
assessments and for regulations dealing with toxic
materials.
                                                          23

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           STUDIES
Title
Office/Division
 Description
Minor or Specialty Uses of
Pesticides for Commodity
Production
Cooperative Agreement
This  cooperative  agreement will  provide data and
information exchanged  on minor and specialty uses
of  pesticides through  the conducting  of project
workshops.    This  date  will  provide a  basis for
registration actions.

(Chemicals:  Pesticides)
Chemical Industry's
Response to Prospective
Environmental Regulations
OPRM/Office of Policy Analysis
This    work    assignment    will    provide    for
consultations  with  officials  from  industry  and
environmental  groups  tc probe  for actions  likely
to  be  taken  in  response  to  changing regulatory
requirements.   Emphasis will  be  given to  end-of-
pipe   controls,   potential   process   changes  or
production  decisions,   £K.d  on  trade-offs  betweer
such possible alternatives.
Strategic Industry Review
for the Organic Chemicals,
Plastics     Synthetic
Fibers Industry
OPRM/Policy Analysis Division
The  purpose of  this  work assignment  is to apply
modeling approaches to assessing  the impact of EPA
regulations   on   the   organics,,   plastics,   and
synthetics  industries  end to investigate possible
regulatory   reform   or   regulatory    efficiency
options.
                                                                      (Chemicals;
                                                                      (Industries:
                                                    Organics}
                                                     Organic chemical, plastics,
                                                     synthetics)
                                                         24

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INDUSTRIAL STUDIES
Title
Office/Division
Description
Chemical Engineering Cost
Support for the Chemicals
MBO Study
OPRM/Office of Policy Analysis
This  work  assignment will  develop  estimates  of
chemical    production   process   economics   and
volume/composition   of  solid   waste   based  on
chemical   engineering   data,   calculation   and
estimates,  A brief overview of the  international
competitiveness  of  the  U.S.   chemicals industry
will also be prepared.

(Industry?  Chemical)
 Summary  of  Hazardous Waste
 Industry Market Forecast
'Studies
 OPRM/Office of Policy analysis
The purpose  of this work assignment is to examine
demand,  pricing,   and  capacity   studies  of  the
commercial hazardous wastes management industry.

(Industry;  Hazardous waste management)
 High  Growth Industry
 Pollution Characterization
 ORD/Office of Exploratory
 Research
The purpose of  this  contract modification  is  to do
a  detailed analysis  of pollution  characteristics
of high growth  industries.
                                                          25

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ECONOMIC STUDIES
Title
Office/Division
Description
Pollution Control Cost
Analysis
Cooperative Agreement
This   cooperative   agreement   will:      relate
engineering   cost  analysis  and   economic  cost
analysis,  assess   suitability   of  current  cost
analysis  for  use  in  environmental  RIA's,  and
provide two case studies.
Analysis of Economic
Benefits of Improved
Information
Cooperative Agreement
This  project will develop  methods  for estimating
the  economic  benefits  of   information  programs
(e.g.,  labeling)  and  methods   for   testing  the
economic  benefits  of  information  on  both  the
health   and  non-health  risks   associated  with
substances  covered  under Section 8 of  the Toxic
Substances Control Act,
Economic Impact of
Defluoridation on Dental
Health
Assistance Amendment
The purpose  of this project  is  to develop a data
base on the  risk of contracting fluorosis by non-
life time residents in high fluoride areas.  It is
an extension of  earlier work  conducted by EPA that
supports the analysis of cost-effective limits for
the installation of fluoride  removal technology in
drinking water.

(Chemical;  Fluoride)
(Media:  Drinking water)
                                                         26

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ECONOMIC STUDIES
Title
Office/Division
Description
National Crop loss
Assessment Networks
Effects of Ozone  in the
Mortheast
Cooperative Agreement
She primary objective  of  this research project is
to define the relationships between yield of major
agricultural  crops  and  closes  of ozone.    This
information will  partially  fulfill  the  need for
data required  to assess  economic  consequences in
the  U.S*  from   crop   exposure  to  gaseous  air
pollutants,

(Chemical;  Ozone)
(Hedia:  Mr)
An Assessment of  the
National Economic Effects
of Ozone on Agricultural
Crops
 Cooperative  Agreement
fhis  project  will assess  the  national economic
consequence  of ozone  damage  to  a set  of annual
crops,  using  computer models.   It  will include
crops  for  which  NCLAN  dose-response  data  are
available;  soybeans,   wheat,   cotton,  barley  and
hay.

(Chemical:  Ozone)
Methods  Development in
Measuring  Benefits of
Environmental Improvement
 Assistance Amendment
this  project will  develop improved methodologies
for determining  the economic benefits of pollution
control and  to  make initial applications of  these
methodologies.
                                                         27

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ECONOMIC STUDIES
Title
Office/Division
 Description
Economic Benefits of
Reduced Heavy Duty Diesel
Emissions
OPRM/Policy Analysis Division
The purpose of  this  work assignment  is  to  evaluate
the  health (cancer  and  noncancer),  soiling,  and
visibility effects  of diesel emissions from heavy
duty vehicles»
Macroeconomic Impacts of
EPA Regulations
OPRM/office of Policy Analysis
This work order will  provide  economic quantitative
estimates     of     historical    and    projected
macroeconomic     impacts      (e.g.      investment
displacement,    changes    in    employment   and
productivity,  price  and output  effects)   of EPA
regulations    on    the   so-called   "smokestack"
industries.

(Industries:   Iron and  steel,  chemical, pulp and
paper,   automobile,  nonferrous  metals,   foundries,
petroleum  refining,   utilities,  municipal   sludge,
solid waste)
                                                         28

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ECONOMIC STUDIES
Title
Office/Division
Description
Financial Analysis  of
St. Louis
OPRM/Office of Policy Analysis
This  work  assignment  will  entail  the  following
tasks:

o    Develop a methodology EPA can use to evaluate
     the  financial  ability of a  local government
     to comply with environmental regulations.

o    Analyze the financial  ability of the City of
     St,   Louis   to   comply  with   environmental
     requirements    of    the    city    operated
     incinerators.

o    Prepare a set  of  questions to be submitted to
     city  officials in  St.  Louis to  elicit the
     data   necessary   to  complete   the  analysis
     described in the second task.

o    Prepare a  written  report on the findings of
     the analysis and the methodology.
                                                          29

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ECONOMIC STUDIES (COST-BENEFIT STUDIES)
Title
Office/Division
Description
Costs and Benefits of
Pesticides Use
Assistance Amendment
This project will provide an analysis of costs and
benefits of the  use  of pesticides on agricultural
crops in Illinois and the U.S.

(Chemicals:  Pesticides)
Research and Demonstration
of Improved Methods for
Carrying Out Benefit-Cost
Analysis of Individual
Regulations
Cooperative Agreement
The  purpose  of  this  project  is  to  develop and
apply improved methods for preparing benefit-cost
analysis of individual proposed regulations.
 Analysis of the Costs and
 •anefits of the Use of
 asticides on Crop and
 ?n-crop Sites in Virginia
 id Other States.
Assistance Amendment
This project will  provide the needed input to the
risk/benefit   regulatory  decisions   on  problem
pesticides  which  could  affect   the  economy  of
Virginia and other states.   The project will also
provide  analysis  methodologies to be  used by the
Agency  in  future  risk/benefit  reviews  involving
pesticides.

(Chemicals:  Pesticides)
                                                         30

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ECONOMIC STUDIES (COST-BENEFIT STUDIES)
Title
Office/Division
Description
Benefit Analysis Using
Indirect of Imputed Market
Methods
Cooperative Agreement
This project  will carry out  economic research to
develop  solutions  for  the  underidentification of
hedonic  demand  curves  for  environmental  public
goods  and demonstrate,  using  suitable pollution
problems.   Also develop and  demonstrate improved
methods  for estimating the regional water-quality
benefits  resulting  from  water  pollution control
requirements.

(Medias  Water)
The Use of Contingent
Valuation Data  for
Benefit/Cost  Analysis in
Water Pollution Control
Assistance Amendment
The purpose of  this  project is  to  develop and  test
a  contingent valuation  instrument which  will be
used   for   a    national    contingent   valuation
experiment, and national benefit estimates will be
calculated.

(Media:  Water)
 The  Representativeness  of
 Case Studies  Used to
 Evaluate  the  Benefits and
 Costs of  the  Organics and
 Plastics  Effluent
 Guidelines
 OPRM/Office  of  Policy Analysis
This   work  assignment  will  characterize   these
regulated   industries,   by  type  and  volume  of
production,    treatment    in    place,    expected
compliance  costs,  etc., and  the environments  its
effluents  effects  (e.g.,  type,  size  and uses of
receiving   water  body)  and  evaluate   the  case
studies within that framework.

(Industry:  Organic Chemicals, Plastics)
(Media:Water)
                                                          31

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ECONOMIC STUDIES (COST-BENEFIT STUDIES)
Title
Office/Division
Description
Estimating the Net
Benefits of Combined Sewer
Overflow Controls for a
Non-Marine Site
OPRM/Office of Policy Analysis
This  project  is  intended  to  generate  the  net
benefits  of water  quality  improvements,  such as
required  for  .major  regulations  under Executive -
Order  12291,   that  are proj e-ctecl to  result from
various  Combined  Sewer  Overflow  (CSO)  control
alternatives for  a non-marine site.   The results
will  be  used   to  formulate and  support a 1985
construction   grants   regulation   amendment   to
require  benefit-cost  analysis   for  CSO  project
applications.                       -

-{Media-: ' Water) -      .           . - .  •     -
                                                         32

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TREATMENT TECHHOLOGY/DEVELOPMENT EVALUATIQS
Title
Office/Division
Description
Removal of Non-Volatile
Chloroorganic Compounds
and Their Precursors by
GAG Adsorption
Grant
The basic  purpose of  this study  is  to determine
the potential  of  activated carbon  treatment for
removal   of    non-purgeable   organic   chlorine
compounds from drinking water.

(Chemicals;  Nonvolatile chloroorganics)
{Media;  Drinking water)
 Iron  Treatment by Sodium
 Silicate &  Chlorine
 Grant
The   purpose  of  this   grant  is  to  determine
fundamentals  of  a new  drinking  water treatment
process, pioneered in Canada,  which is capable of
keeping  .iron  &  manganese   in  solution,   thus
preventing color,  taste, & stain problems.

(Chemicals;   Iron, manganese)
(Media;  Drinking  water)
 Destruction of Poly-
 chlorinated Biphenyls
 {PCB's)  - Environmental
 Applications of Sodium
 Polyethylene Glycolate
 Complexes
 Assistance Amendment
The  objective  here is to -develop and optimiiaize  a
potentially  useful  chemical   process  for   the
degradation   of   PCB's   and   other   halogenated
compounds  so as  to minimize their  impact in  the
environment.     The  specific  objectives  is   to
determine  the  effectiveness of the  NaPEG  reaction
in the treatment of PCB-contaminated soils.

(Chemical;  Polychlorinated biphenyls)
(Media:  Land)
                                                          33

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TREATMENT TECHNOLOGY/DEVELOPMENT EVALUATION
Title
Office/Division
Description
Recovery of Metal Values
from Metal Finishing
Sludges
Cooperative Agreement
This  project  will  use  a specific  technology to
remove metals  from sludges and oils.  An operating
history  will  be  developed  and  output  streams
monitored   to   test   the  compatibility  of   this
process  with  incineration  technology as  well as
conventional   sanitary   landfill  or  landforming
systems.

(Chemicals:  Metals)
Genetic Studies on a New
Anaerobe From Digester
Sludge Able to Metabolize
Aromatic Ring Structures
Grant
This  work will  determine  if degradation  is by a
curable  and  transmissible plasmid,  compare it to
related   strains,   and   characterize  defective
mutants in the pathway.

(Chemicals;  Aromatic hydrocarbons)
Trihalomethane Precursor
Removal by Coagulation
Techniques in Lime-
Softening Plant
Cooperative Agreement
This cooperative  research agreement will evaluate
the  practical  and  economic  aspects   of  certain
polymeric    coagulants    for   removing   organic
precursor material  before that material can react
with   chlorine   to  produce   unacceptably  high
concentrations of trihalomethanes.

(Chemicals:  Trihalomethanes)
                                                         34

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TREATMENT TECHNOLOGY/DEVELOPMENT EVALUATION
Title
Office/Division
                                                                       Description
Venturi Scrubber
Performance and
Optimization
Grant
The  objectives  of  this   research  are,   through
carefully controlled experiments,  to develop data
that  will  allow  further  refinement   of   venturi
performance    and    optimization   theory,    to
demonstrate  the extent  to which  the   theoretical
benefit from venturi optimization is achieved, and
to develop design criteria.

(Media:  Air)
TTield Research on  Radon
Removal with  GAC
Grant
The  purpose of  this  grant is  to determine  cost
effectiveness  of using  granular activated  carbon
to remove Radon  from private groundwater supplies.

(Chemical;  Radon)
(Media:  Groundwater)
Superfund—Assessing
Alternative Remedial
Actions
 OPRM/Policy Analysis Division
The purpose  of  this work assignment is to evaluate
key issues in  the Superfund program that relate to
determining  the degree of cleanup  required  at the
hazardous  waste sites  and  to conduct  an analysis
of  the cost-effectiveness of  alternative remedial
actions  at  a  particular site.   This  information
will   be   used   in  formulating  an  approach  for
assessing  the  benfits associated with  cleaning up
Superfund  sites.
                                                          35

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TREATMENTTECHNOLOGY/DEVELOPMENT  EVALUATION
Title
Office/Division
Description
Air Pollution Control
Handbook
ORD/Center for Environmental
Research Information
This incremental funding contract will provide for
an  operation  and  maintenance  handbook  on  air
pollution control  technology.   This handbook will
help assist  State and  local  air pollution agency
personnel  determine   the   compliance  status  of
stationary sources.
Water Treatment Data for
Pesticides
ORD/Municipal Environmental
Research Laboratory
This task  will compile and  develop  data on water
treatment  for  pesticides.    Data collected will
concern  pesticides  used  in and  around drinking
water sources.

(Chemicals;  Pesticides)
(Media:  Drinking water)
Evaluation of Reverse
Osmosis for Removal of
Inorganic Contaminants
ORD/Muncipal Environmental
Research Laboratory
This  incremental   funding  action  will  provide
treatment   data   on  use   of   reverse   osmosis
technology  to  remove  inorganic  contaminants from
drinking water.    information  being used  to help
State, local agencies,  consultants, and utilities
in selecting proper treatment for small community
problems,

(Chemicals;  Inorganics)
(Media:   Drinking water)
                                                         36

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TREATMENT TECHNOLOGY/DEVELOPMENT EVALUATION
Title
Of fice/Pivision
                                                                      Description
Evaluation of Treatment
Methods for Removal of
Inorganic Contaminants
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
This contract modification will evaluate treatment
methods for removal of inorganic contaminants from
small   community  water   supplies.     Laboratory
studies  and pilot  studies  using  a  mobile pilot
plant   trailer   are  being   conducted  to   develop
engineering  data on  methods to  remove  inorganic
contaminants from groundwater.

(Chemical(s);  Inorganic s)
(Media:  Ground  water)
Field  Testing/Techniques
.for  Pilot Air,  Water and
Solid  Waste Pollution
 ORD/Industrial Environmental
 Research Laboratory
 Cincinnati,  OH
This  incremental funding action  will provide  for
acquisition of  field data in response to Regional
and Program Office needs.  It will allow sampling
at  development  sites  as targets  of opportunity
present  themselves.    Sites  to be studied  include
oil   shale  processing  facilities,   other  energy
development    facilites   and    other   selected
industrial facilites.

 (Chemical(s)  :
                                                                       (Industryties):  Oil Shale Processing
 Evaluation of the Thermal
 Reactor infra-red (IR)
 Oven
 ORD/Industrial Environmental
 Research Laboratory
 Cincinnati,  OH
 This  cooperative agreement  is  an innovative  pro-
 cess  which will  evaluate  how the thermal  reactor
 oven  can be  employed to control volatile  organic
 compound  (VOC) emissions from paint processes.

 (Chemical(s);  VOCs
 (Industry(ies):   Paint Baking
                                                          37

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TREATMENT TECHNOLOGY/DEVELOPMENT EVALUATION
Title
Office/Division
Description
Hazardous Waste
Incineration Performance
Assessments and Support
ORD/Industrial Environmental
Reserach Laboratory
Cincinnati, OH
This  interagency  agreement  will  provide  field
scale performance  data and  technical  support for
Regulatory  Impact  Analysis.    This  study  will
upgrade   the   Oak   Ridge   National   Laboratory
incinerator  engineering  model  as  part  of  the
overall   evaluation   supportable   and   accurate
performance  data   to  -assist   OSW   with  permit
application decisions.

(Chemical(s ) ;
                                                                      ( Indus try (ies) :
Evaluation of New and
Emerging Technogies in the
Metal Finishing Industry
ORD/Industrial Environmental
Research Laboratory
Cincinnati, OH
This cooperative  agreement will evaluate the most
promising  emerging  technologies  for   the  metal
finishing  industry.   This  will provide industry,
the  Agency,  and  permit   writers  with data  to
consider advances  in pollution control at a lower
cost.

(Chemical(s):
(Industry(ies):  Metal Finishing
Evaluation of Catalytic
Oxidation Technology for
Control of VOC Emissions
crom Industrial Sources
ORD/Industrial Environmental
Research Laboratory
Research Triangle Park, NC
This  incremental funding  action will  do testing
and  evaluation  to  provide  documentation on  the
performance    of    catalytic    oxidation    for
consideration  as   a   viable  control  option  to
support NSPS and NESHAP regulations

(Chemical(s):
(Industry(ies);  Catalytic Oxidation Technology
                                                         38

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WASTE MANAGEMENT/RESOURCE RECOVERY
Title
Office/Division
Description
Screening Protocols  for
Use in Predicting Land
Treatability of Wastes
Cooperative Agreement
This  project  will  examine  screening  tools  for
predicting when  wastes can be safely  applied to
hazardous waste land treatment facilities.

(Media:  Land)
 Use  of  Direct Freeze
 Conditioning Techniques to
 Improve Biological Sludge
 Dewatering Characteristics
 Grant
This   project  will  examine  direct   freeze-thaw
conditioning   techniques   using  hydrate  forming
refrigerant  gases  as  an  alternative  to -chemical
conditioning  techniques.
.Dewatering Wastewater
 Treatment .Sludge by
 Clathrate Freezing
 Preliminary Freon -11
 Studies
 Cooperative Agreement
The  purpose  of  this  project  is  to  conduct a
preliminary   investigation   on   the    technical
feasibility   >of  a   proposed  sludge   dewatering
process  employing a  liquid  refrigerant to form a
complex with  the  water in sludge.

(Chemical;  Preon)
(Media:  Water)
                                                          39

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WASTE MANAGEMENT/RESOURCE RECOVERY
Title
Office/Division
Description
Chemical Resistance of
Flexible Membrane Liners
Cooperative Agreement
The purpose of this project is to develop guidance
to  assist   users  in   the   broad   selection  of
materials  for  containment of  hazardous  wastes.
Concentration  will   be  on  the   best  flexible
membrane    to    use     under   specific    waste
concentrations .

(Chemical:  Hazardous Wastes)
Biological Monitoring
Systems for Hazardous
Waste Sites
Cooperative Agreement
In  this  project chlorinated  hydrocarbons  will be
administered  to  dairy  cows.    their  excretary
pathways will be monitored.   Data obtained will be
useful to apply to field conditions for monitoring
was te.
                                                                      (Chemicals:  Chlorinated hydrocarbons)
Limitations and Energetics
of Hydrophobia (nonpolar)
Sorption of Organic
Compounds by Soils and
Sediments
Grant
In  this  project  the  critical  parameters  of the
sorption  of  organics to  soils  and sediments will
be determined.

(Chemicals:  Organics)
(Media:  Land)
                                                         40

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WASTE MANAGEMENT/RESOURCE RECOVERY
Title
Office/Division
Description
Gene Engineering  of  Yeasts
for the Degradation  of
Hazardous Waste
Cooperative Agreement
The purpose  of this  project is  to  develop yeast
via  genetic   engineering   techniques  that  will
degrade highly chlorinated organic compounds.

(Chemicals;  Chlorinated organics)
Critical  Review and
Summary of Analytical
Methods for the
Determination of the
Hydraulic Integrity of
Synthetic Liners
Cooperative  Agreement
This project  will  provide a review and summary of
methods  available  in  literature  and  use  this
information for determining hydraulic integrity of
synthetic liners.   Recommendations  to be made for
methods  available  or  that  can  be  modified for
determining  hydraulic  conductivity  of  synthetic
liners.
                                                                       (Media;  Land)
                                                          41

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WASTE MANAGEMENT/RESOURCE RECOVERY
Title
Office/Division
Description
The Effect of Industrial
Wastes on Soil Biota
Assistance Amendment
This project  will investigate  the  effect of high
loading    rates    on    the    degradation    and
transformation  of  organics and inorganics  in the
applied wastes.

(Chemicalst  Organicsr inorganics)
(Media:  Land)
Downhole Sensing Methods
for Hazardous Waste Site
Monitoring
Cooperative Agreement
This project  will provide  testing  and evaluation
of downhole  sensing equipment and  techniques for
hazardous  waste  monitoring  and detection  using
small diameter shallow boreholes.
                                                                      (Media:  Land)
Rapid Estimation of
Pollutant Concentration
ORD/Office of Health and
  Environment Assessment
The purpose  of  this  incremental funding action is
to develop multimedia methods for rapid estimation
of   pollutant   concentrations   resulting   from
releases of hazardous wastes.
                                                                      (Chemicals:  Hazardous Wastes)
                                                         42

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WASTE MANAGEMENT/RESOURCE RECOVERY
Title
Office/Division
                                                                       Description
Impoundment/Waste  Lagoon
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
This     work      assignment     will     develop
impoundment/waste lagoon spillage  controls.   This
technology  will  be  used by  OERR to  help State,
Federal, and private clean-up personnel.
 Illinois  Geological Survey
ORD/Municipal  Environmental
Research  Laboratory
Cincinnati,  OH
This  cooperative agreement  will  investigate the
failure  mechanism  and  migration  of  industrial
chemicals  at  a  hazardous  waste  landfill.    In
addition, reasons will  be  sought for why the clay
soils  are  transmitting  hazardous wastes much more
rapidly  than  predicted  when   the  facility  was
designed.

(Chemicalst  Hazardous wastes)
(Media:  Land)
 Cover Design and
 Infiltration Control
 ORD/Municipal Environmental
 Research Laboratory
 Cincinnati,  OH
This   inter-agency  agreement  will  develop   and
compile various methods  to  control  infiltration at
hazardous  waste  disposal facilities.   Information
will  also be  provided  to  revise  and  update  the
Technical  Research Document.   Improved design  for
covers  over  the  disposal  area  should  result in
lower  amounts  of  rainfall reaching the wastes  and
less  leachate production.    Technical assistance
capabilities  to  the  Agency are  also included in
the overall work statement.   This information will
be  used  by  permitting  officials  in  review  and
approval of RCRA cover systems permits.
(Media:  Land)
                                                          43

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                          RECOVERY
Title
Of fice/Divi sion
 Description
Assessment of Tine
Settlements/Subsidence
Effects on Cover Systems
ORD/Municipal Envirormental
Research Laboratory
Cincinnati, OH
This  inter-agency agreement will  produce  a final
research  report  which  will  document  practical
field   observations  at  existing  sites  on  the
cause/effect  relationship  of  subsidence  on cover
system  integrity.  The  theoretical approach will
utilize  the  classical  consolidation theory  and
projected  contaminant  scenarios  (i.e.  90%  full
drum)  to determine the maxiimjn settling  of  the
cover  system.   Roth  approaches will be  used  to
determine  when   it  will   be  cost-effective  to
construct  the  final  cover  (i.e.,  put cover  on
first and repair  or let it  settle then construct
final cover).
Innovative Hazardous Waste
Control Technology
ORD/lndustrial Environmental
Reserach Laboratory
Cincinnati, OH
The  purpose of  this cooperative agreement  is to
"study yeasts, photosynthetic plant and genetically
engineered  organisms to destroy hazardous waste,
This  technology  is  being  evaluated  to  seek more
cost-effective  techniques  for  control  of highly
toxic waste.

(Chanical(s);  Hazardous Wastes
(Industry(ies);
Performance and
Engineering Assessment of
Cincinnati Metropolitan
Sewage District
Incineration Facility
ORD/lndustrial Environmental
Research Laboratory
Cincinnati, OH
The  purpose of  this 'cooperative agreement  is to
provide a  full  scale,  continuous performance and
operating  data  on  a commercial hazardous  waste
incinerator  facility and to provide data  in sup-
port of incinerator scale-up criteria research

{Chemical(s):  Hazardous Wastes
(Industry (ies);
                                                        44

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EMERGENCY RESPONSE
Title
Office/Division
Description
Poiychlorinated Biphenyl
(PCB) Transformer Fires
ORD/Waste Management Division
This contract  modification will  develop  a report
on  PCB   transformer  fires  which  will  include
looking at  nature,  safety protocols, and remedial
measures.

(Chemical;  Poiychlorinated Mphenyls)
Safety and  Health
Reference Manual
ORD/Office  of  Research Program
Management
The purpose  of  this incremental funding action is
to  develop  safety  and health  references manuals
with  standard operating  precautions, procedures,
and  plans  to follow  when  dealing  with unknown
hazardous materials.
                                                                       (Chemicals  Hazardous materials)
 Oil  Spill  Clean-up
 Equipment;and Techniques
 OKD/Municipal Environmental
 Research  Laboratory
 Cincinnati,  OH
This work assignment will  evaluate  commercial, and
develop improved, oil  spill  clean-up equipment and
techniques.   This information  and  equipment will
be  used  by  the  Office  of   Etaergency   Remedial
Response  to  reduce  State  and  Federal   clean-up
cost.
                                                         45

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EMERGENCY RESPONSE
Title
Office/Division
Description
Upgrade Treatment of
Highly Viscous Oil/Water
Emulsions
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
This work assignment will aide in the upgrading of
treatments    of    highly    viscous    oil/water
emulsions.   These  techniques and information will
be used  by OERR to  help State  and Federal field
personnel clean-up spilled oil effectively.
Evaluate Effectiveness of
Oil Spill Dispersants
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
This    work    assignment   will    evaluate   the
effectiveness    of    oil    spill    dispersants.
Information and techniques will be used by OERR to
guide  State  and  Federal personnel  in dispersant
use for oil spill clean-up.
Clean-up Residuals
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
This   work  assignment   will  develop   new  and
innovative techniques  for on-site destruction and
disposal of clean-up residuals.
                                                         46

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EMERGENCY RESPONSE
Title
Office/Division
Description
Collection and Treatment
of Volatile and Gaseous
Materials
ORD/Municipal Environmental
Research Laboratory
Cincinnati, OH
                                     for
This     work      assignment     will
collection/treatment    techniques    f<
volatile and gaseous materials

(Chemicals;  Volatile and gaseous materials)
develop
spilled
Hazardous Materials
Technical Handbooks
 ORD/Municipal Environmental
 Research Laboratory
 Cincinnati,  OH
This  work   assignment  will   develop  hazardous
material  spill prevention  technial  handbooks  to
guide State and Federal field personnel and reduce
spill frequency.

(Chemicals:  Hazardous materials)
 Hazardous Spill Removal
 Technical•Handbooks
 ORD/Municipal Environmental
 Research Laboratory
 Cincinnati,  OH
This  work assignment in  an ongoing contract will
develop  a users  manual on  current equipment and
techniques  for the  prevention,  control, cleanup,
removal,   and  disposal   of   spilled  hazardous
materials.-  This  information will be used by OERR
to  guide  State  and Federal  field  personnel  in
cleanup  activities  and to  reduce  the  associated
costs.
                                                          47

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POLICY STUDIES/REGUIATORY CONTROL OPTIONS
Title
Of fice/Divisi on
Description
Cooperative agreement for
Program in Environmental
Health and Public Policy
Cooperative Agreement
This  will   serve  as  a   pilot   program  for  a
cooperative inter-university program on the effect
of  toxic   chemicals   on   human  health  and  the
environment.   The program will  link  the natural
and the  policy sciences through specific research
projects,   individual  policy   assessments,   and
analyses.    This  will, assure  the  relevance  of
activities to practical problems.
Defining the Role of
Federal and Private Sector
Activities in Solving
Municipal Environmental
Problems
Cooperative Agreement
The purpose  of the workshop  would  be to identify
environmental  problems  associated   with  drinking
water?  municipal  wastewater,  and  municipal solid
and hazardous wastes  that  have  a  potential  for
solution through research and development.

(Chemical;  Hazardous wastes)
(Media:  Drinking water, water, land)
International Conference
for Safety Evaluation and
Regulation of Chemicals
Cooperative Agreement
This  cooperative agreement  will provide  for the
organization  and  administration  of  the  second
International Conference for Safety Evaluation and
Regulation of  Chemicals to be  held  in Cambridge,
Massachusetts, October 24 - 28,  1983.
                                                         48

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POLICY STUDIES/REGULATORY CONTROL OPTIONS
Title
Office/Division
Description
Legal Analysis of  Toxic
Torts Cases
OPRM/Office of Policy Analysis
The  purpose   of  this  work   assignment  is  to
facilitate  development  of  an  Agency  position of
legislative  proposals  regarding  toxics  victims
compensation.    Information  will be  developed on
the  efficiency  and  effectiveness  of  the  legal
system in compensating persons injured by exposure
to toxic substances»
Analysis  of  the  Cost of
Clean  Air and Clean Water
Report
 OPRM/Office  of Policy Analysis
This work  assignment will  analyze  the effects of
the  changes  in  air  and water  pollution control
regulations for the following industries:

(Industries:
                                                                      For  Air:   Lead acid batteries,  surface  coatings,
                                                                      and mobile  sources.
                                                                      For   Water:      Petroleum   refining,
                                                                      enameling, and Pharmaceuticals *)

                                                                       (Media:   Air, water)
                                                                                porcelain
                                                          49

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POLICY STUDIES/REGULATORY CONTROL OPTIONS
Title
Office/Division
                                                                      Description
Analysis of Impacts of
Incinerator Regulations
OPRM/Office of Policy Analysis
This  work  assignment  will  provide for  cost and
risk  analysis  for  several  alternative regulatory
options for incineration as  specified by  EPA  under
the Resource Conservation and Recovery Act.  This
work  will   synthesize  technology,  engineering,
economic, and  health risk data  into a consistent
impacts framework.
Clues to the Domestic
Environmental Agenda for
the Next Three Decades
ORD/Office of Exploratory
  Research
The  purpose   of   this  contract  is  to  perform
research  analysis  designed  to  provide  improved
information  on  future  environmental  trends  and
problems.    The  report  developed  will  identify
problems  of  declining importance and problems of
continuing and growing importance.
                                                         50

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METHODOLOGY DEVELOPMENT VALIDATION - CHEMICAL ANALYSES
Title
Office/Division
Description
Structure Activity Methods
for Estimating the Aquatic
Toxicity and Degradability
of Industrial Chemicals
Cooperative Agreement
The purpose of  this  project is to test the table-
driven  feature  and  adjacency  correction  of  the
MINTER  system  and  test   the  graph  isomorphism
enumerator   by   encoding   available   literature
reviews of qualitative hydrolysis data.

(Media:  Water)
Prediction of Aqueous
Solubilities, Activity
Coefficients and Henry's
Law Constants of
Industrial Chemicals
Cooperative Agreement
The  objectives  of  this  project are  to formalize
and  refine  the  methods   to calculate  molecular
surface  area  and  volume,  to  develop structure-
solubility relationships between molecular surface
area/volume  and  water  solubility,  formalize the
relationship between molecular surface area/volume
and activity coefficients.
Biomonitoring of Trace
Organic Compounds
Cooperative Agreement
This   work   will   cover   (1)   validation   of  a
correlation between log P and reverse phase liquid
chromatographic  retention time;  (2)  analysis of
fish  from  the  Great  Lakes;   (3)   determine  the
feasibility of  linking the quantitative structure
activity relationships  (SWAR)  data  base  with the
mass   spectral   data  base;  and    (4)  determine
metabolic products of selected organic chemicals.

(Chemicals;   Organics)
(Media:  Water)
                                                         51

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METHODOLOGY DEVELOPMENT - TREATMENT PROCESSES AND MONITORING
Title
Office/Pivision
Description
Methods Development and
Water Pollution Control
Analysis
Assistant Amendment
The  purpose  of  this  project  is  to  determine
feasibility  and  validity  of  using  equations  for
one  area  to  estimate  benefits for  another areai
and  to  improve the methodology and  demonstrate a
more efficient  approach to estimates  of national
benefits from improved water quality.

(Media:  Water)
                                                          52

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METHODOLOGY DEVELOPMENT - HEALTH AND ENVIRONMENTAL STUDIES
Title
Office/Division
Description
Speciation of
Environmental Pollutants
and Biological Materials
Grant
This project  entails  the development  of  a method
for the identification and quantification of metal
species in a variety of environmental samples.

(Chemicals:  Metals)
 Earthworms  as  a
 Bioassessment  Tool
Cooperative Agreement
This  project   will  provide   an   evaluation  of
earthworms   for    bioassessment   of   hazardous
materials   utilizing  growth,   reproduction  and
neurophysiologieal measurements.

(Chemicals:  Hazardous materials)
                                                          53

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STATISTICAL ANALYSES
Title
Office/Division
Description
SIMS Five Year Study on
Statistical and
Environmental Factors in
Health
Cooperative Agreement
This   cooperative  agreement   will   entail  the
following   activities:    (1)    methodology   for
assessing the  relationships  between air pollution
exposure  levels  s  effects on  human populations,
(2)  measurement   of   ambient   air  quality,  (3)
meterological modeling and model verification, and
(4) statistical  properties of  the  time and space
variability of air pollutant concentrations.

(Media:  Air)
                                                         54

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MODELING
Title
Office/Division
                                                                      Description
Persistence in Model
Ecosystems
Cooperative Agreement
In   this   project   mathematical   analyses   of
environmental  models will  be  performed.   These
analyses   will   be  global    analyses   of   the
persistence  of  system   components.    The  models
analyzed will  be system  models of multicomponent
systems   that   are  of   the   kinds    used   in
environmental science.
Scientific Assessment of
Air Quality Modeling
Assistance Amendment
This project will provide  for  the organization and
oversight of scientific review of various types of
air   quality  models;  planning  and  organizing
scientific   workshops  related  to   air  quality
modeling;  and  response   to   specific  scientific
questions on issues related to air quality models,

(Media:  Mr)
                                                         55

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DATA BASE DEVELOPMENT
Title
Office/Division
Description
Management and Analysis of
Data of EPA-sponsored
Field Studies
Cooperative Agreement
This  cooperative  agreement  will  establish  and
manage a data  base  from large EPA sponsored field
studies  (MISTT,  STATE/TPS,  PEPE-NEROS  and CWPS)
and   quantify  and   parameterize  physical   and
chemical processes  acting on plumes.   Information
will be widely disseminated.

(Media:  Air)
                                                         56

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SAMPLING & MONITORING — GENERAL
Title
Office/Division
Description
Evaluation of New and
Emerging Technologies in
the Metal Finishing
Indus try
Cooperative Agreement
This project  will combine  the  efforts of ongoing
development projects with supplemental information
identifying      and      assessing       "emerging
technologies".   This will  be  accomplished by on-
site   sampling   and   measurement    studies   to
characterize system performance and cost.

(Industry;  Metal Finishing)
 Groundwater  Sampling for
 Monitoring Purpose
 Assistance Amendment
The  purpose of  this  project is  to determine  the
most cost-effective, reliable methods  for  sampling
groundwater   for  organic   pollutants  and   then
provide  regulatory  agencies  with clear  field-
testing  guidelines  for  how  routine monitoring
efforts should be undertaken.
                                                                       (Chemicals;  Organics)
                                                                       (Media:  Groundwater)
 Handbook on Sampling and
 Wasteload Allocation
 ORD/Center for Environmental
 Research Laboratory
This  incrementally funded contract will develop  a
handbook  on sampling  and wasteload allocation of
conventional pollutants  and  metals.   This  contract
will  also  provide  for workshops  on the  methodology
developed.

 (Chemicals:  Metals)
                                                          57

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SAMPLING, ANALYSIS S MONITORING — CHEMICAL ANALYSIS - SPECIAL TOPICS
Title
Off ice/Pivi s ion
Description
Development of Biomembrane
Toxicity Electrodes
Grant
This  grant entails  the development  of electrode
systems  for  detecting  and   characterizing  toxic
substances in environmental samples.
A Project to Develop
Emission Spectroscopic
Methods for the
Determination of the
Halogen and other Non-
Metals Via Direct Current
Plasma Excitation
Grant
This project  will develop  emission spectroscopic
methods for the  determination of halogens, boron,
carbon,   phosphorous,   silica,   and   sulfur  in
environmental  samples  by  using  direct  current
plasma  excitation  in  combination  with  a  high
resolution echelle spectrometer.

(Chemicals;  Halogens,  boron, carbon, phosphorus,
             silica,  sulfur)
                                                         58

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SAMPLING, ANALYSIS & MONITORING — ENVIRONMENTAL MONITORING
Title
Office/Division
Description
Toxic Chemicals in the
Environment:  A Program of
Field Measurement
Cooperative Agreement
The  continuation  of  this  Cooperative  Agreement
will  focus  on  the  ambient  air measurement  of a
large   number   of  selected   hazardous  organic
chemicals.
                                                                      (Chemicals!  Organics)
                                                                      (Mediaz  Air)
Water Quality Workshop
Cooperative Agreement
This  workshop  will enable  scientists  from EPA,
universities and the private sector to present and
critically  examine new  scientific  approaches  to
the  measurement  of  complex  toxic  mixtures  and
chemicals in aquatic systems.

(Media:  Water)
Field Surveys of Dosages
and Exposures to Air
Pollution Using Personal
Dosimeters
Assistance Amendment
In  this  study  a  sample  of  the  participants in
polluted  cities  will be  equipped  with personal
particulate monitors*  Portable monitors will  also
be   placed  in   strategic   indoor   and  outdoor
locations    frequented    by   the   participants.
Activity  monitors  will be  maintained.   Data  will
be analyzed using multiple regression techniques.

(Media:  Air)
                                                         59

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SAMPLING, ANALYSIS S MONITORING — ENVIRONMENTAL MONITORING
Title
Office/Division
Description
Quality Assurance for
Environmental Monitoring
Methods (AQ-IV)
ORD/Environmental Monitoring
  Systems Laboratory  Research
  Triangle Park, NC
The purpose of  this  incremental funding action is
to provide new or improved analytical and sampling
techniques  for   compounds   in  ambient  air  and
particulate matter.

(Chemicals;      Formaldehyde
                 Acrylonitrile
                 Benzene
                 Chloroform
                 1,2-Dichloroethane
                 1,1,1-Trichloroethane
                 Chlorobenzenes
                 Carbon Tetrachloride
                 Dichloromethane
                 Trichloroeth bromodiehloromethane
                 Vinyl Chloride
                 Te trachloroe thylene
                 Arsenic Trioxide
                 Arsenates
 Environmental Pollution
 Monitoring
 ORD/Environmental Monitoring
   Systems Laboratory Research
   Triangle Park,  NC
This   incremental  funding  action  will   provide
quality   assurance   for  technical   support   on
Environmental Pollutant  Monitoring*
                                                          60

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SAMPLING, ANALYSIS & MONITORING — ENVIRONMENTAL MONITORING
Title
Office/Division
Description
Symposium of Air Pollutant
Measuring and Monitoring
ORD/Center for Environmental
  Research Laboratory
This    contract    modification   provides    for
conferences     on    . advanced    state-of-the-art
monitoring and measuring of air pollutants.

(Media;  Air)
GEMS for Designated
AP-State-of-the-Art
Investigation
ORD/Enviromnental Monitoring •
  Systems laboratory  Research
  Triangle Park, NC
This  incrementally funded  contract  will develop,
evaluate,  and  validate  a  Chemical  Environmental
Monitoring   System  (GEMS)   for   Designated  air
pollutants    (AP)-State-of-the-Art   Investigation
into  vinyl  chloride CEMS  and develop performance
specifications and quality assurance procedures.

(Chemical;  Vinyl chloride)
                                                         61

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                                          INDEX




Acrylonitrile (107-13-1)	  60
Amrronia  (7664-41-7)	..	  18
Aromatic hydrocarbons.	  34
Arsenates (SEQ:  2)	  60
Arsenic Trioxide  (7440-38-2)	  60
Benzene  (71-43-2)	  60
Boron  (7440-42-8)	  58
Carbon (7440-44-0)		.............................  58
Carbon Tetrachloride (56-23-5)	  60
Chloranine (127-65-1)..........................................  7
Chlorinated hydrocarbons (SECh 11).....	  2, 40
Chlorinated organics	41
Chlorine (7782-50-5)	  7
Chlorine dioxide  (7790-93-4)	  7
Chlorobenzenes  (108-90-7)...........	...		  60
Chloroform (67-66-3)	...	  60
2-Chlorophenol  (95-57-8)..«	  7
4-Chlorophenol  (106-48-9)		...  7
Chromium Compounds (744-47-3)	  19
1,2-Dichloroethane (75-35-4)		  60
Dichloromethane (75-09-2)	  60
2?4-Dichlorophenol (120-83-2)		......	7
Ethylene oxide  (75-21-8)	,	  15
Fenthion (55-38-9)			,	.17
Fluoride (16984-48-8)		  26
Formaldehyde (50-00-0)			  11, 60
Ereon  (SEQ:  9).			  39
Halogenated organics.	  21
Halogens.	  58
Hazardous materials	  45, 53
Hazardous pollutants	  15
Hazardous solid wastes.	  22
Hazardous wastes	  21, 23,  40,  42?  43,  48
                                            62

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Hydrocarbons (SEQs 11)	  3
Inorganics.	  36, 37,  42
Iron  (7439-89-6)	  33
Lead  (7439-92-1)	.,	  12, 14
Maled	  17
Manganese  (7439-96-5)			  33
Metals (SEX): 73).	  34, 53,  57
Neuron Specific Proteins	12
Nonvolatile chloroorganics	  33
Qrganics	  2, 3,  18,  19,  24,  40, 42,
    		  51, 57,  59
Ozone (10028-15-6)		........  11, 27
Pesticides		  11, 21,  24r  30,  36
Phosphorus (7723-14-0)	.....		  58
Photochemical oxidants (SE0s 79)	-.	  11, 12
Polychlorinated Biphenyls (13336-36-3)	  9, 33, 45
Radon (10043-92-2)	,	  35
Silica (7631-86-9)				  58
Solvents	  4
Sulfur (7704-39-4)		.....  58
Synthetic dyes.	  4
Tetrachloroethylene (124-18-4)	  60
1 ,lfl-Trichloroethane (71-55-6)	  60
Tr ichloroeth brotnodichloromethane	60
Trihaloraethanes (SEO:  28)	  8, 34
Uranium-238 (7440-61-1)		  8
Vinyl Chloride (75-01-4)	  60, 61
Volatile & gaseous materials.	  47
Volitile Organic Compounds.	  37
                                            63

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                                          INDEX


    MEDIA                                                       H4GE


Air	  3,  5,  11,  12,  13, .14, 20, 22, 27,
			  35, 49,  53,  54, 56,  59, 61
Drinking water.	  7,  8,  21,  26,  33, 36, 48
Groundwater. ...,	2,  4,  23,  35,  37, 57
Land	33, 39-43, 48
Metals	  34
Water..	  17, 18,  31,  32, 39,  48, 49, 51, 52,
	59
                                            64

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                                        INDEX
     IMXBTRZ                                              •
 Automobile	 28
 Catalytic Oxidation Technology	,	 38
 Chemical.	i..,~........	,	 25, 28
 Foundries	 28
 Hazardous waste management	„. 25, 44
 Iron and steel	,	28
 Lead acid batteries.	 49
 Metal Finishing,	 38, 57
 Mobi le Sources	 49
 Municipal sludge.	•.	 28
 Nonferrous metals	 28
- Oi 1 Shade Processing	37
 Organic Chemical	 24, 31
 .Paint Raking	.	 37
 -Petroleum refining.	 49
' Pharmaceuticals.	 49
 Elastics.	 24, 31
 •Porcelain enameling.	49
. Pulp and paper	 28
 So lid waste.	 28
• Surface coatings	 49
; Synthetics.	24
 ' Utilities.	 28
                                             65

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