19 November 2008                                                             Page 1


    Preliminary Reference List for 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD):
        In Vivo Mammalian Dose-Response and Epidemiological Studies

't Mannetje, A., D. McLean, S. Cheng, P. Boffetta, D. Colin and N. Pearce. 2005.
Mortality in New Zealand workers exposed to phenoxy herbicides and dioxins.  Occup.
Environ. Med.  62(1):34-40.

Abadin, H.G., C.H. Chou and FT. Llados.  2007.  Health effects classification and its
role in the derivation of minimal risk levels: immunological effects.  Regul. Toxicol.
Pharmacol. 47(3):249-256.

Abbott, B.D., T.M. Lin, NT. Rasmussen, R.M. Albrecht, J.E. Schmid and R.E. Peterson.
2003. Lack of expression of EGF and TGF-alpha in the fetal mouse alters formation of
prostatic epithelial buds and influences the response to TCDD. Toxicol. Sci.
76(2):427-436.

Abraham,  K., A. Geusau, Y. Tosun, H. Helge, S. Bauer and J. Brockmoller. 2002.
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the
measurement of hepatic cytochrome  P450 1A2 induction.  Clin. Pharmacol. Ther.
72(2): 163-1 74.

Adamsson, A., U.  Simanainen, M. Viluksela, J. Paranko and J. Toppari. 2008.  The
effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on foetal male rat steroidogenesis.  Int. J.
Androl.

Ahmad, K. 2002.  Agent Orange no longer linked to childhood AML.  Lancet Oncol.
3(4): 199.

Alaluusua, S.  and P.L. Lukinmaa. 2006. Developmental dental toxicity of dioxin and
related compounds-a review.  Int.  Dent. J. 56(6):323-331.

Alaluusua, S., H. Kiviranta, A. Leppaniemi, P. Holtta, P.L. Lukinmaa, L. Lope, A.L.
Jarvenpaa, M. Renlund, J. Toppari, H. Virtanen, M. Kaleva and T. Vartiainen. 2002.
Natal and neonatal teeth in relation to environmental toxicants. Pediatr. Res.
52(5):652-655.

Alaluusua, S., P.  Calderara, P.M. Gerthoux, P.L. Lukinmaa, 0. Kovero, L. Needham,
D.G. Patterson, Jr., J. Tuomisto and P. Mocarelli. 2004.  Developmental dental
aberrations after the dioxin accident in Seveso. Environ. Health Perspect.
Allen, D.E. and L.J. Leamy.  2001.  2,3,7,8-tetrachlorodibenzo-p-dioxin affects size and
shape, but not asymmetry, of mandibles in mice.  Ecotoxicology.  10(3): 167-1 76.

Alsharif, N.Z. and E.A. Hassoun. 2004. Protective effects of vitamin A and vitamin E
succinate against 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced body wasting,
hepatomegaly, thymic atrophy, production of reactive oxygen species and DNA damage
in C57BL/6J mice.  Basic Clin. Pharmacol.  Toxicol. 95(3): 131 -138.

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19 November 2008                                                              Page 2


Ambrus, J.L., A. Islam, S. Akhter, W. Dembinski, M. Kulaylat and C.M. Ambrus. 2004.
Multiple medical problems following agent orange exposure. J. Med. 35(1-6):265-269.

Amin, S., R.W. Moore, R.E.  Peterson and S.L. Schantz. 2000.  Gestational and
lactational exposure to TCDD or coplanar PCBs alters adult expression of saccharin
preference behavior in female rats.  Neurotoxicol. Teratol. 22(5):675-682.

Anger, D.L. and W.G. Foster.  2008. The link between environmental toxicant exposure
and endometriosis.  Front Biosci. 13:1578-1593.

Aragon, A.C., M.B. Goens, E. Carbett and M.K. Walker. 2008a.  Perinatal
2,3,7,8-tetrachlorodibenzo-p-dioxin exposure sensitizes offspring to angiotensin
Il-induced hypertension.  Cardiovasc. Toxicol. 8(3):145-154.

Aragon, A.C., P.G. Kopf, M.J. Campen, J.K. Huwe and M.K. Walker.  2008b.  In utero
and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult
cardiac gene expression and adult cardiac and renal morphology. Toxicol. Sci.
101(2):321-330.

Arisawa, K.,  H. Takeda and  H. Mikasa.  2005. Background exposure to
PCDDs/PCDFs/PCBs and its potential health effects:  a review of epidemiologic studies.
J. Med. Invest. 52(1-2):10-21.

Atallah, E. and C.A. Schiffer. 2007. Agent Orange, prostate cancer irradiation and
acute promyelocyic leukemia (APL): is there a link? Leuk. Res. 31(5):720-721.

Aulerich, R.J., B. Yamini and S.J. Bursian. 2001.  Dietary exposure to
3,3',4,4',5-pentachlorobiphenyl (PCB 126) or 2,3,7,8-tetrachlorodibenzo-p-dixon (TCDD)
does not induce proliferation of squamous epithelium  or osteolysis in the jaws of
weanling rats.  Vet. Hum. Toxicol.  43(3): 170-171.

Baccarelli, A., A.C. Pesatori, S.A. Masten, D.G. Patterson, Jr.,  L.L. Needham, P.
Mocarelli, N.E. Caporaso, D. Consonni, J.A. Grassman, P.A. Bertazzi and M.T. Landi.
2004.  Aryl-hydrocarbon  receptor-dependent pathway and toxic effects of TCDD in
humans: a population-based study in Seveso, Italy. Toxicol. Lett. 149(1-3):287-293.

Baccarelli, A., A.C. Pesatori, D. Consonni, P. Mocarelli,  D.G. Patterson, Jr., N.E.
Caporaso, P.A. Bertazzi  and M.T. Landi.  2005.  Health  status and plasma dioxin levels
in chloracne cases 20 years after the Seveso, Italy accident. Br. J. Dermatol.
152(3):459-465.

Baccarelli, A., C. Hirt, A.C. Pesatori, D.  Consonni,  D.G.  Patterson, Jr., P.A. Bertazzi,  G.
Dolken and M.T. Landi.  2006. t(14;18) translocations in lymphocytes of healthy
dioxin-exposed individuals from Seveso, Italy. Carcinogenesis. 27(10):2001-2007.

Baccarelli, A., S.M. Giacomini, C. Corbetta,  M.T. Landi,  M. Bonzini, D. Consonni, P.
Grille, D.G. Patterson, A.C. Pesatori and P.A. Bertazzi.  2008.  Neonatal thyroid function
in Seveso 25 years after maternal exposure to dioxin. PLoS. Med.  5(7):e161.

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19 November 2008                                                              Page 3


Badawi, A.F., E.L. Cavalieri and E.G. Rogan.  2000. Effect of chlorinated hydrocarbons
on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of
17beta-estradiol  in female Sprague-Dawley rats.  Carcinogenesis.  21 (8): 1593-1599.

Bagchi, D., J. Balmoori, M. Bagchi, X. Ye, C.B. Williams and S.J. Stohs. 2002.
Comparative effects of TCDD, endrin, naphthalene and chromium (VI) on oxidative
stress and tissue damage in the liver and brain tissues of mice. Toxicology.
175(1-3):73-82.

Barrett, D.H., R.D. Morris, F.Z. Akhtarand J.E. Michalek. 2001.  Serum dioxin and
cognitive functioning among veterans of Operation Ranch Hand. Neurotoxicology.
22(4):491-502.

Bell, D.R., S. Clode, M.Q. Fan, A. Fernandes, P.M. Foster, T. Jiang, G. Loizou, A.
MacNicoll, B.C. Miller, M. Rose, L. Iran and S. White.  2007a. Toxicity of
2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. I: No
decrease in epididymal sperm count after a single acute dose. Toxicol. Sci.
99(1 ):214-223.

Bell, D.R., S. Clode, M.Q. Fan, A. Fernandes, P.M. Foster, T. Jiang, G. Loizou, A.
MacNicoll, B.C. Miller, M. Rose, L. Iran and S. White.  2007b. Relationships between
tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs, and toxicity in the
developing male Wistar(Han) rat. Toxicol. Sci. 99(2):591-604.

Bell, D.R., S. Clode, M.Q. Fan, A. Fernandes, P.M. Foster, T. Jiang, G. Loizou, A.
MacNicoll, B.C. Miller, M. Rose, L. Tran and S. White.  2007c. Toxicity of
2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. II:  Chronic
dosing causes developmental delay. Toxicol. Sci. 99(1):224-233.

Bemis, J.C., N.F. Alejandro, D.A. Nazarenko, A.I. Brooks, R.B. Baggs and T.A.
Gasiewicz. 2007. TCDD-induced alterations in gene expression profiles of the
developing mouse paw do not influence morphological differentiation of this potential
target tissue. Toxicol. Sci. 95(1):240-248.

Besteman, E.G., K.L. Zimmerman and S.D. Holladay. 2005.
Tetrachlorodibenzo-p-Dioxin (TCDD) Inhibits Differentiation and Increases Apoptotic
Cell Death of Precursor T-Cells in the Fetal  Mouse Thymus. J. Immunotoxicol.
2(2): 107-114.

Besteman, E.G., K.L. Zimmerman, W.R. Huckle, M.R. Prater, R.M. Gogal, Jr. and S.D.
Holladay.  2007.  2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or diethylstilbestrol (DES)
cause similar hematopoietic hypocellularity and hepatocellular changes in murine fetal
liver, but differentially affect gene expression.  Toxicol.  Pathol. 35(6):788-794.

Birnbaum, L.S. and J. Tuomisto. 2000.  Non-carcinogenic effects of TCDD in animals.
FoodAddit. Contam.  17(4):275-288.

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19 November 2008                                                             Page 4


Birnbaum, L.S. and S.E. Fenton. 2003. Cancer and developmental exposure to
endocrine disrupters. Environ. Health Perspect. 111(4):389-394.

Blond, B. 2000.  [Risks of dioxins on health are still poorly evaluated].  Soins. Pediatr.
Pueric.(197):10.

Boas, M., U. Feldt-Rasmussen, N.E. Skakkebaek and K.M. Main. 2006.  Environmental
chemicals and thyroid function. Eur. J. Endocrinol.  154(5):599-611.

Boersma, E.R. and C.I. Lanting.  2000.  Environmental exposure to polychlorinated
biphenyls (PCBs) and dioxins. Consequences for longterm neurological and cognitive
development of the child lactation.  Adv. Exp. Med. Biol.  478:271-287.

Boffetta, P.  2006. Human cancer from environmental pollutants: the epidemiological
evidence.  Mutat. Res. 608(2): 157-162.

Bohn, A.A., K.S. Harrod, S. Teske and B.P. Lawrence. 2005.  Increased  mortality
associated with TCDD exposure in mice infected with influenza A virus  is  not due to
severity of lung injury or alterations in Clara cell protein content. Chem. Biol. Interact.
155(3): 181-190.

Bolt, H.M. and K. Golka. 2007. [Occupational cancer-burdens of the past or actual
threat?].  Dtsch. Med. Wochenschr. 132(4): 133-134.

Boverhof, D.R., L.D. Burgoon, C. Tashiro, B. Chittim, J.R. Harkema, D.B.  Jump and
T.R. Zacharewski. 2005.  Temporal and dose-dependent hepatic gene expression
patterns in mice provide new insights into TCDD-Mediated hepatotoxicity. Toxicol. Sci.
85(2): 1048-1063.

Bowers, O.J., K.B. Sommersted, R.T. Sowell, G.E. Boling, W.H. Hanneman, R.G. Titus
andG.K.  Dekrey.  2006. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces
Leishmania major burdens in C57BL/6 mice.  Am. J. Trop. Med. Hyg. 75(4):749-752.

Boyle, S.H., W.G. Jackson and E.G. Suarez.  2007. Hostility, anger, and  depression
predict increases in C3 over a 10-year period.  Brain Behav. Immun.  21 (6):816-823.

Brody, J.G., K.B. Moysich, 0. Humblet, K.R. Attfield, G.P. Beehler and  R.A. Rudel.
2007. Environmental pollutants and breast cancer: epidemiologic studies. Cancer.
109(12Suppl):2667-2711.

Brouillette, J. and R. Quirion. 2008. The common environmental pollutant
dioxin-induced memory deficits by altering  estrogen pathways and a major route of
retinol transport involving transthyretin.  Neurotoxicology. 29(2):318-327.

Bruner-Tran, K.L., G.R. Yeaman, M.A. Crispens, T.M. Igarashi and K.G. Osteen.  2008.
Dioxin may promote inflammation-related development of endometriosis.  Fertil. Steril.
89(5 Suppl): 1287-1298.

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19 November 2008                                                             Page 5


Brunnberg, S., P. Andersson, M. Lindstam, I. Paulson, L. Poellingerand A. Hanberg.
2006. The constitutively active Ah receptor (CA-Ahr) mouse as a potential model for
dioxin exposure-effects in vital organs. Toxicology.  224(3): 191-201.

Buchanan, D.L., S. Ohsako, C. Tohyama, P.S. Cooke and T. Iguchi. 2002. Dioxin
inhibition of estrogen-induced mouse uterine epithelial mitogenesis involves changes in
cyclin and transforming growth factor-beta expression.  Toxicol. Sci. 66(1):62-68.

Butler, D.  2005.  US abandons health study on Agent Orange. Nature. 434(7034):687.

Byers, J.P., K. Masters, J.G. Sarverand E.A. Hassoun.  2006.  Association between the
levels of biogenic amines  and superoxide anion production in brain regions of rats after
subchronic exposure to TCDD. Toxicology. 228(2-3):291-298.

Calkosinski,  I., M.  Dobrzynski, M. Cegielski, A. Sieja and M. Calkosinska.  2006. [The
multifaceted effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in organisms,
especially dentition changes].  Postepy Hig. Med. Dosw. (Online. ). 60:237-240.

Calle, E.E., H. Frumkin, S.J. Henley, D.A. Savitz and M.J. Thun. 2002.
Organochlorines and breast cancer risk. CA Cancer J. Clin.  52(5):301-309.

Camacho, I.A., M.R. Hassuneh, M. Nagarkatti and P.S. Nagarkatti. 2001. Enhanced
activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD)-induced immunotoxicity in peripheral T cells. Toxicology.  165(1):51-63.

Camacho, I.A., M. Nagarkatti and P.S. Nagarkatti. 2004a. Evidence for induction of
apoptosis in T cells from murine fetal thymus following perinatal exposure to
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).  Toxicol. Sci. 78(1):96-106.

Camacho, I.A., M. Nagarkatti and P.S. Nagarkatti. 2004b. Effect of
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on maternal immune response during
pregnancy. Arch. Toxicol. 78(5):290-300.

Cao, Y., G. Winneke,  M. Wilhelm, J. Wittsiepe, F. Lemm, P. Furst, U. Ranft, M. Imohl,
M. Kraft, B. Oesch-Bartlomowicz and U. Kramer.  2008.  Environmental exposure to
dioxins and polychlorinated biphenyls reduce levels of gonadal hormones in newborns:
results from the Duisburg  cohort study. Int. J. Hyg. Environ. Health. 211(1-2):30-39.

Casey, B. 2005. Environmental contaminants and maternal thyroid function.  Am. J.
Obstet. Gynecol. 193(6): 1889-1890.

Chang, H., Y.J. Wang, L.W.  Chang and P. Lin.  2005. A histochemical and pathological
study on the interrelationship between TCDD-induced AhR expression, AhR activation,
and hepatotoxicity in mice. J. Toxicol. Environ. Health A. 68(17-18): 1567-1579.

Chao, H.R., S.L. Wang, L.Y. Lin, W.J. Lee and 0. Papke.  2007.  Placental transfer of
polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in Taiwanese mothers
in relation to menstrual cycle characteristics.  Food Chem. Toxicol.  45(2):259-265.

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Charnley, G. and R.D. Kimbrough. 2006. Overview of exposure, toxicity, and risks to
children from current levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related
compounds in the USA.  Food Chem. Toxicol. 44(5):601-615.

Chaudhuri, A. and M.D. Harris. 2003. 'Proximal-type' epithelioid sarcoma:  is Agent
Orange still at large? Ann. R. Coll. Surg. Engl. 85(6):410-412.

Chen, J., L.S. Laughlin, A.G.  Hendrickx, K. Natarajan, J.W. Overstreet and  B.L. Lasley.
2003. The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on chorionic
gonadotrophin activity in pregnant macaques. Toxicology.  186(1-2):21-31.

Chen, H.L., H.J. Su, Y.J. Wang, Y.L. Guo, P.C. Liao and C.C. Lee.  2006a.   Interactive
effects between CYP1A1 genotypes and environmental polychlorinated
dibenzo-p-dioxins and dibenzofurans exposures on liver function profile.  J. Toxicol.
Environ. Health A.  69(3-4):269-281.

Chen, H.L., H.J. Su, Y.L. Guo, P.C. Liao, C.F. Hung and C.C. Lee.  2006b.
Biochemistry examinations and health disorder evaluation of Taiwanese  living near
incinerators and with low serum PCDD/Fs levels. Sci. Total Environ.  366(2-3):538-548.

Cheng, S.B., S. Kuchiiwa, I. Nagatomo, Y. Akasaki, M. Uchida, M. Tominaga, W.
Hashiguchi, T. Kuchiiwa and  S. Nakagawa.  2002.  2,3,7,8-Tetrachlorodibenzo-p-dioxin
treatment induces c-Fos expression in the forebrain of the Long-Evans rat.  Brain Res.
931 (2): 176-180.

Cherniak, I., D.A. Grassman and A.A. Shelepchikov. 2005. [Markers of  impact and
effects of dioxines in firemen  who participated in fire extinguishing at "Irkutskcabel"
plant].  Med. Tr. Prom  Ekol.(12):41-46.

Cho, H.J., E.J. Hahn, J.A. Hwang, M.S. Hong, S.K.  Kim, H.R. Pak and J.H. Park. 2006.
Enhanced expression of plasma glutathione peroxidase in the thymus of mice treated
with TCDD and its implication for TCDD-induced thymic atrophy. Mol. Cells.
21(2):276-283.

Choi, S.S., M.A. Miller and P.A. Harper. 2006. In utero exposure to
2,3,7,8-tetrachlorodibenzo-p-dioxin induces amphiregulin gene expression in the
developing mouse ureter. Toxicol. Sci. 94(1): 163-174.

Chu, I., P. Lecavalier, H. Hakansson, A. Yagminas, V.E. Valli, P. Poon and M. Feeley.
2001. Mixture effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated
biphenyl congeners in rats. Chemosphere.  43(4-7):807-814.

Codier, S. and D. Bard. 2000. [Paternal exposure to dioxin and sex ratio in the
offspring]. Rev. Epidemiol. Sante Publique. 48(6):590-591.

Colborn, T. 2002.  Impact of  Endocrine Disrupters on Brain Development and
Behaviour. Proceedings of a  conference. 15-20 September 2001, Sicily,  Italy. Environ.
Health Perspect. 110 Suppl 3:335-449.

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19 November 2008                                                              Page 7


Collins, J.J., R.A. Budinsky, C.J. Burns, L.L. Lamparski, M.L. Carson, G.D. Martin and
M. Wilken.  2006.  Serum dioxin levels in former chlorophenol workers. J. Expo. Sci.
Environ. Epidemiol.  16(1)76-84.

Collins, L.L., M.A. Williamson, B.D. Thompson, D.P. Dever, T.A. Gasiewicz and L.A.
Opanashuk. 2008. 2,3,7,8-Tetracholorodibenzo-p-dioxin exposure disrupts granule
neuron precursor maturation in the developing mouse cerebellum.  Toxicol. Sci.
103(1): 125-136.

Connor, K.T. and L.L. Aylward. 2006. Human response to dioxin: aryl hydrocarbon
receptor (AhR) molecular structure, function, and dose-response data for enzyme
induction indicate an impaired human AhR. J. Toxicol. Environ. Health B Grit Rev.
9(2): 147-171.

Consonni, D., A.C. Pesatori, C. Zocchetti, R. Sindaco, L.C. D'Oro, M. Rubagotti and
P.A. Bertazzi. 2008.  Mortality in a population exposed to dioxin after the Seveso,  Italy,
accident in 1976: 25 years of follow-up.  Am. J. Epidemiol.  167(7):847-858.

Cordier, S. 2008.  Evidence for a role of paternal exposures in developmental toxicity.
Basic Clin.  Pharmacol. Toxicol.  102(2): 176-181.

Correa-Villasenor, A., J.  Cragan, J. Kucik,  L. O'Leary, C. Siffel and L. Williams. 2003.
The Metropolitan Atlanta Congenital Defects Program: 35 years of birth defects
surveillance at the Centers for Disease Control and Prevention. Birth Defects Res. A
Clin. Mol. Teratol.  67(9):617-624.

Cranmer, M., S. Louie, R.H. Kennedy, P.A. Kern and V.A. Fonseca. 2000. Exposure to
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with hyperinsulinemia and
insulin resistance. Toxicol. Sci.  56(2):431-436.

Crofton, K.M., E.S. Craft, J.M. Hedge, C. Gennings, J.E. Simmons, R.A.  Carchman,
W.H. Carter, Jr. and M.J. DeVito. 2005.  Thyroid-hormone-disrupting chemicals:
evidence for dose-dependent additivity or synergism. Environ. Health Perspect.
113(11): 1549-1554.

Croutch, C.R., M. Lebofsky, K.W. Schramm, P.P. Terranova and K.K.  Rozman. 2005.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and
1,2,3,4,7,8-hexachlorodibenzo-p-dioxin (HxCDD) alter body weight by decreasing
insulin-like growth factor I (IGF-I) signaling. Toxicol. Sci. 85(1):560-571.

Dalton, T.P., J.K. Kerzee, B. Wang,  M. Miller,  M.Z. Dieter, J.N. Lorenz, H.G. Shertzer,
D.W. Herbert and A. Puga. 2001. Dioxin exposure is an environmental risk factor for
ischemic heart disease.  Cardiovasc. Toxicol.  1(4):285-298.

Darras, V.M.  2008.  Endocrine disrupting polyhalogenated organic pollutants interfere
with thyroid hormone signalling in the developing brain.  Cerebellum.  7(1):26-37.

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Davies, R., B. Clothier, S.W. Robinson, R.E. Edwards, P. Greaves, J. Luo, T.W. Gant,
T. Chernova and A.G. Smith.  2008.  Essential role of the AH receptor in the dysfunction
of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chem. Res.
Toxicol.  21(2):330-340.

Davis, B.J., E.A. Mccurdy, B.D. Miller, G.W. Lucier and A.M. Tritscher. 2000. Ovarian
tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Cancer
Res. 60(19):5414-5419.

De Roos, A.J., P. Hartge, J.H. Lubin, J.S. Colt, S.  Davis, J.R. Cerhan, R.K.  Severson,
W. Cozen, D.G. Patterson, Jr., L.L. Needham and N. Rothman.  2005. Persistent
organochlorine chemicals in plasma and risk of non-Hodgkin's lymphoma. Cancer Res.
65(23): 11214-11226.

Dearstyne, E.A. and N.I. Kerkvliet. 2002.  Mechanism of
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced decrease in anti-CDS-activated
CD4(+) T cells: the roles of apoptosis, Fas, and TNF.  Toxicology.  170(1 -2): 139-151.

Debacker, N., A. Sasse, N. van Wouwe, L. Goeyens,  F. Sartor and O.H. van. 2007.
PCDD/F levels in plasma of a belgian population before and after the 1999  belgian
PCB/DIOXIN incident.  Chemosphere. 67(9):S217-S223.

Derkenne, S., C.P. Curran, H.G. Shertzer, T.P. Dalton, N. Dragin and D.W.  Nebert.
2005. Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-)
knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the  mouse
Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice. Pharmacogenet. Genomics.
15(7):503-511.

Desaulniers, D., K. Leingartner, J. Russo, G. Perkins, B.C. Chittim, M.C. Archer, M.
Wade and J. Yang. 2001. Modulatory effects of neonatal exposure to TCDD, or a
mixture of PCBs, p,p'-DDT, and p-p'-DDE, on methylnitrosourea-induced  mammary
tumor development in the rat. Environ. Health Perspect.  109(7):739-747.

Dhulipala, V.C., W.V. Welshons and C.S. Reddy.  2006. Cell cycle proteins in normal
and chemically induced abnormal secondary palate development: a review.  Hum. Exp.
Toxicol.  25(11):675-682.

Dietert, R.R. 2008.  Developmental Immunotoxicology: Focus on Health Risks.  Chem.
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Kerkvliet, N.I.,  D.M. Shepherd and L. Baecher-Steppan. 2002.  T lymphocytes are
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Kim, H.A., E.M. Kim, Y.C. Park, J.Y. Yu, S.K. Hong, S.H. Jeon, K.L. Park, S.J. Hur and
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Ko, K., H.M. Theobald and R.E. Peterson.  2002. In utero and lactational  exposure to
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Ko, K., R.W. Moore and R.E. Peterson.  2004a.  Aryl hydrocarbon receptors in
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Ko, K., H.M. Theobald, R.W. Moore and R.E. Peterson.  2004b. Evidence that inhibited
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Kogevinas, M. and G. Janer. 2000. [Health effects of dioxins].  Med. Clin. (Bare. ).
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Kopf, P.G., J.K. Huwe and M.K. Walker. 2008.  Hypertension, Cardiac Hypertrophy,
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Kransler, K.M., B.P. McGarrigle, R.J. Russell and J.R. Olson. 2008. Effects of
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Kuchiiwa, S., S.B. Cheng, I. Nagatomo, Y. Akasaki, M. Uchida,  M. Tominaga,  W.
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Kwon, Y.I., J.D. Yeon, S.M.  Oh and K.H. Chung. 2004.  Protective effects of
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La Merrill, M., D. Baston, M. Denison, L. Birnbaum, D. Pomp and D.W. Threadgill.
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Langer, P. 2008. Persistent organochlorinated pollutants (PCB, DDE, HCB, dioxins,
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Lawrence, B.P., T.K. Warren and H. Luong. 2000. Fewer T lymphocytes and
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Lawrence, B.P. and B.A. Vorderstrasse. 2004. Activation of the aryl hydrocarbon
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Lee,  D.H., I.K.  Lee, K. Song, M. Steffes, W.  Toscano, B.A. Baker and D.R. Jacobs, Jr.
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Lee, J.H., D. Sul, E. Oh, W.W. Jung, K.W. Hwang, T.S. Hwang, K.C. Lee and N.H.
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Lensu, S., R. Miettinen, R. Pohjanvirta, J. Linden and J. Tuomisto.  2006. Assessment
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Lewis, B.C., S. Hudgins, A. Lewis, K. Schorr, R. Sommer, R.E. Peterson, J.A. Flaws
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Li, X.M. and J. Li. 2003. [Environmental hormones and their effects on human health].
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Li, B., H.Y.  Liu, L.J. Dai, J.C.  Lu, Z.M. Yang and L. Huang. 2006. The early embryo
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Lim, C.K., M. Danton, B. Clothier and A.G. Smith.  2006. Dihydroxy-,
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Lin, T.M., K. Ko,  R.W. Moore, D.L. Buchanan, P.S. Cooke and R.E. Peterson.  2001.
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Lin, T.M., U. Simanainen, R.W. Moore and R.E. Peterson. 2002a.  Critical windows of
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Lin, T.M., K. Ko,  R.W. Moore, U. Simanainen, T.D. Oberley and R.E. Peterson.  2002b.
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Linden, J., M. Korkalainen, S. Lensu, J. Tuomisto and R. Pohjanvirta. 2005.  Effects of
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Link, B., T. Gabrio, I. Zollner, I. Piechotowski and B. Kouros. 2007.  Sentinel health
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Loertscher, J.A., T.M. Lin, R.E. Peterson and B.L. Allen-Hoffmann. 2002.  In utero
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Longnecker, M.P.  and J.L. Daniels.  2001. Environmental contaminants as etiologic
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Luebeck, E.G., A.  Buchmann, S. Stinchcombe, S.H. Moolgavkar and M. Schwarz.
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Luebke, R.W., C.B. Copeland, M. Daniels, A.L. Lambert and M.I. Gilmour. 2001.
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Petroff, B.K., X. Gao, K.K. Rozman and P.P. Terranova. 2000.  Interaction of estradiol
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