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INNOVATIVE RESEARCH FOR A SUSTAINABLE FUTURE
PARIS III - ERA'S SOLVENT SUBSTITUTION SOFTWARE TOOL
(PROGRAM FOR ASSISTING THE REPLACEMENT OF INDUSTRIAL SOLVENTS)
Overview
For decades, industrial and
manufacturing companies have used
chemical solvents in the
development of products and
processes. This is due to the
effective performance of solvents.
However, some of these solvents
may be harmful to human health and
the environment. As a result, many
companies are looking to find safer,
more sustainable solvent
alternatives.
That's why the United States
Environmental Protection Agency
(EPA) developed PARIS III - a
solvent substitution software tool
that allows users to select more
sustainable solvent replacements
with properties closest to those
traditionally used by industry.
PARIS III
PARIS III is one of EPA's Chemical
Safety for Sustainability research
program efforts. The software
application contains a database of
over five thousand solvents used by
industry.
PARIS III uses a screening
technology to evaluate the thousands
of high priority chemicals for
Paris I
Program for Assisting the Replacement of
Industrial Solvents
PARIS III
Solvent Design Software
from US EPA
Tech Support
Developers and Acknowlegements
Paris III is a trademark of the US EPA
potential toxicity. The software also
blends solvents in different
proportions to find a variety of
suitable substitutes. A ranked list of
solvent mixtures is then created
within minutes for the user to select
from.
Who Can Use It?
PARIS III is designed for companies
looking for sustainable alternatives
to reduce the environmental impact
of their industrial processes. It can
also be useful when designing new
industrial processes. Interested
individuals include:
• Chemists
• Environmental Engineers
• Environmental Consultants
• Solvent Engineers
• Solvent Technicians
1
Users do not have to
change equipment or
modify their chemical
processes in order to
adopt safer, more
sustainable solvents.
U.S. Environmental Protection Agency
Office of Research and Development
Installation
PARIS III is free public domain
software. Users can install PARIS
III software and download the user's
guide directly to their computer
from:
http ://www2. epa. gov/chemical-
research/program-assisting-
replacement-industrial-solvents-iii-
paris-iii
EPA/600/F-14/408
May 2015
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EPA's Chemical Safety for Sustainability Research Program
EPA's chemical safety research focuses on improving the safe production, use, and disposal of chemicals.
This is a major priority in support of actions to protect human health and the environment. The Agency's
Chemical Safety for Sustainability research program provides the decision-support tools needed to meet
that priority, while advancing innovative ways to evaluate chemicals, conduct risk management, and
prioritize time-critical research.
http://www2.epa.gov/aboutepa/about-chemical-safety-sustainability-research-program
Summary
PARIS III solvent substitution
software tool is one of EPA's
chemical safety decision-support
tools. It offers a cost-effective
approach to finding solvent
substitutes less harmful to
human health and the
environment. Users do not have
to change equipment or modify
their chemical processes in order
to adopt safer, more sustainable
solvents.
More information
EPA's Chemical Research -
http://www2.epa.gov/chemical-
research
EPA Chemical Safety for
Sustainability Fact Sheet -
http://www2.epa.gov/sites/produ
ction/files/2013-
12/documents/css-fact-sheet.pdf
References
Harten, P.P. "Program for Assisting
the Replacement of Industrial
Solvents (PARIS III)," 18th Annual
Green Chemistry & Engineering
Conference, North Bethesda MD,
June 17-19 (2014).
Harten, P.P. "Finding Greener
Solvent Mixtures to Replace
Solvent Mixtures Used in
Manufacturing Processes," 3rd
International Congress on
Sustainability Science & Engineering
(ICOSSE ' 13), Cincinnati OH,
August 11-15(2013).
Cabezas, H., P.P. Harten, and M.R.
Green, "Designing Greener
Solvents," Chemical Engineering
Vol. 107, No. 3, 109 (2000).
Li, M., P.P. Harten, and H. Cabezas,
"Experiences in Designing Solvents
for the Environment," Industrial and
Engineering Chemistry Research,
41, 5867 (2002).
Harten, P.P., and G. Salama,
"PARIS II, the Search for Cleaner
Solvent Replacements for RCRA
Chemicals," CleanTech, Vol. 4,
Number 11, 20(2004).
Contact
Paul P. Harten, Ph.D.
ParisIII(@,epa.gov
U.S. Environmental Protection Agency
Office of Research and Development
EPA/600/F-14/408
May 2015
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