Glyphosate Update
May 8-9, 2019 Pesticide Program Dialogue Committee Meeting
Background:
	Glyphosate is a broad-spectrum non-selective herbicide registered for use on many
agricultural crops, in non-crop areas, in residential areas, for aquatic weed control, and in
commercial settings. It is also registered for use on glyphosate-resistant crop varieties
including corn, soybean, canola, cotton, sugar beets, and wheat.
	EPA initiated registration review for the widely used herbicide glyphosate (RoundUp) in
2009.
	In 2015, an International Agency for Research on Cancer (IARC) report classified glyphosate
as "probably carcinogenic to humans." All other international fora, including all regulatory
bodies, have concluded that glyphosate is unlikely to be carcinogenic.
	As part of registration review, EPA released draft human health and ecological risk
assessments for glyphosate in December 2017. EPA's assessment concluded that glyphosate
is not likely to be carcinogenic to humans.
	In March 2018, EPA opened a 60-day public comment period on draft human health and
ecological risk assessments with supporting documents for glyphosate.
	EPA received 250,000 public comments on the draft assessment. The majority of comments
are from mass mailing campaigns; approximately 200 are distinct substantive comments
being reviewed.
	EPA announced the proposed interim registration review decision in late April 2019. The
proposed interim registration review decision outlines proposed mitigation measures to
reduce potential ecological risks.
	Under a settlement agreement with the Center for Biological Diversity, EPA is scheduled to
complete a biological evaluation on glyphosate by 2020 and, if necessary, initiate an
Endangered Species Act consultation with the U.S. Fish and Wildlife Service and the
National Marine Fisheries Service by 2020.
Overview of Health Findings:
	Our assessment found no meaningful risks to human health when the product is used
according to the pesticide label.
	The agency's scientific findings are consistent with the conclusions of science reviews by a
number of other countries as well as the 2017 National Institutes of Health Agricultural
Health Survey.
Overview of Proposed Interim Decision:
	In its 2019 proposed interim decision for glyphosate, EPA is proposing the following
mitigation and label changes:
o Spray drift management measures (e.g., release height, droplet size, and wind speed
restrictions) to reduce off-site exposure to non-target wildlife,
o Weed resistance management labeling (e.g., information on mode of action, scouting

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instructions, and reporting instructions for weed resistance),
o Label consistency measures including updating the presentation of maximum
application parameters, updating the environmental hazards statement for aquatic use,
and clarification on rotational crop timing,
o EPA is committed to protecting pollinators, including the monarch butterfly, from
pesticide exposure. As with all other herbicides, EPA has updated the label language
for these pesticides to raise awareness of their potential effects to pollinator habitat
and direct users to instructions on minimizing spray drift. EPA's strategy to protect
the monarch butterfly also includes collaborating with federal, state, and other
stakeholders on conservation efforts and promoting best management and integrated
pest management practices to reduce spray drift and help preserve pollinator habitat.

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