&EPA
United States
"n,al™	EPA Analytical Methods for PFAS in Drinking Water
EPA's new validated Method 533 focuses on "short chain" per- and polyfluoroalkyl substances (PFAS)
(i.e., those with carbon chain lengths of 4 to 12). Method 533 complements EPA Method 537.1
(published November 2018) and can be used to test for 11 additional PFAS. Using both methods, a total
of 29 unique PFAS can be effectively measured in drinking water.
Analyte
Abbreviation
CASRN
Method
533
Method
537.1
11 -Chloroeicosafluoro-3-oxaundecane-1 -sulfonic acid
11CI-PF30UdS
763051-92-9
X
X
9-Chlorohexadecafluoro-3-oxanonane-1 -sulfonic acd
9CI-PF30NS
756426-58-1
X
X
4,8-Dioxa-3H-perfluorononanoic acid
ADONA
919005-14-4
X
X
Hexafluoropropylene oxide dimer acid
HFPO-DA
13252-13-6
X
X
Perfluorobutanesulfonic acid
PFBS
375-73-5
X
X
Perfluorodecanoic acid
PFDA
335-76-2
X
X
Perfluorododecanoic acid
PFDoA
307-55-1
X
X
Perfluoroheptanoic acid
PFHpA
375-85-9
X
X
Perfluorohexanoic acid
PFHxA
307-24-4
X
X
Perfluorohexanesulfonic acid
PFHxS
355-46-4
X
X
Perfluorononanoic acid
PFNA
375-95-1
X
X
Perfluorooctanoic acid
PFOA
335-67-1
X
X
Perfluorooctanesulfonic acid
PFOS
1763-23-1
X
X
Perfluoroundecanoic acid
PFUnA
2058-94-8
X
X
1H,1H, 2H, 2H-Perfluorohexane sulfonic acid
4:2FTS
757124-72-4
X

1H,1H, 2H, 2H-Perfluorooctane sulfonic acid
6:2FTS
27619-97-2
X

1H,1H, 2H, 2H-Perfluorodecane sulfonic acid
8:2FTS
39108-34-4
X

Nonafluoro-3,6-dioxaheptanoic acid
NFDHA
151772-58-6
X

Perfluorobutanoic acid
PFBA
375-22-4
X

Perfluoro(2-ethoxyethane)sulfonic acid
PFEESA
113507-82-7
X

Perfluoroheptanesulfonic acid
PFHpS
375-92-8
X

Perfluoro-4-methoxybutanoic acid
PFMBA
863090-89-5
X

Perfluoro-3-methoxypropanoic acid
PFMPA
377-73-1
X

Perfluoropentanoic acid
PFPeA
2706-90-3
X

Perfluoropentanesulfonic acid
PFPeS
2706-91-4
X

N-ethyl perfluorooctanesulfonamidoacetic acid
NEtFOSAA
2991-50-6

X
N-methyl perfluorooctanesulfonamidoacetic acid
NMeFOSAA
2355-31-9

X
Perfluorotetradecanoic acid
PFTA
376-06-7

X
Perfluorotridecanoic acid
PFTrDA
72629-94-8

X
Office of Water (MS-140)
EPA 815-B-19-021
December 2019

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