Peer Review Draft Risk Evaluation for Trichloroethylene Systematic Review Supplemental File: Data Quality Evaluation of Environmental Releases and Occupational Exposure Data CASRN: 79-01-6 February, 2020


PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
&EPA
United States	Office of Chemical Safety and
Environmental Protection Agency	Pollution Prevention
Risk Evaluation for
T richloroethylene
Systematic Review Supplemental File:
Data Quality Evaluation of
Environmental Releases and Occupational Exposure Data
CASRN: 79-01-6
CI. H
CI CI
February, 2020

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This document is a compilation of tables for the data extraction and evaluation for
Tricholoethylene (TCE). Each table shows the data point or set or information element that
was extracted and evaluated from a data source in accordance with Appendix D of the
Application of Systematic Review in TSCA Risk Evaluations. If the source contains more than
one data set or information element, the review provides an overall confidence score for each
data set or information element that is found in the source. Therefore, it is possible that a
source may have more than one overall quality/ confidence score.
Table of Contents
Releases to the Environment
Occupational Exposure
Facility
Page
3
53
230
Explanatory Notes
These explanatory notes provide context to understand the short comments in the data evaluation tables.
Domain
Metric
Description of Comments Field
Reliability
Methodology
Indicates the sampling/analytical methodology, estimation method, or
type of publication
Repre sentativene ss
Geographic Scope
Indicates the country of the study, publication, or underlying data
Applicability
Indicates whether the data are for a condition of use within scope of the
Risk Evaluation
Temporal Representativeness
Provides the year of study, publication, or underlying data
Sample Size
Describes the distribution of the sample or underlying data
Accessibility / Clarity
Metadata Completeness
Describes the completeness of the metadata
Variability and Uncertainty
Metadata Completeness
Indicates if study or publication addresses variability and uncertainty of
the data or information
2

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Releases to the Environment
DO NOT CITE OR QUOTE

Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Annual Release Quantity (kg/yr):
Release Days per Year:
Number of Sites:
Use
Spill/Leak
None
water and land
Estimate
105007
105007
1
1

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Medium
X 1
2
peer revied article, non-standard sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
High
Unacceptable
Low
High
X 1
x 2
x 2
x 1
1
8
6
1
US
Accidental release, not in scope
1979, 39 years old
Sample size is sufficently large to be representative.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Time period, number of samples, and mean provided.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
Discusse potential reasons why TCE was not found in certain
places.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.4.

Continued on next
page

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
Landrigan, P. J.,Stein, G. F.,Kominsky, J. R.,Ruhe, R. L.,Watanabe, A. S.. 1987. Common-source community and industrial
exposure to trichloroethylene. Archives of Environmental Health.
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
65261
5

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Fugitive releases
fugitive air
air
TRI reporting
6708081
783
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

tains TRI data directly rather than from secondary sources
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001, 17 years old
Metric 5:
Sample Size
High
x 1
1
Data is industry-wide TRI data with 783 facilities reporting
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed.
Overall Quality Determination^
Unacceptable
4 Metric Mean Score: 2.3.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
6

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Stack air
air
TRI reporting
6841572
783
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
x 1
1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

Metric 6:
Metadata Completeness
Low
x 1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Surface water
water
TRI reporting
758
783
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
x 1
1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

Metric 6:
Metadata Completeness
Low
x 1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Underground Injection
Underground Injection
TRI reporting
131
783
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
x 1
1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

Metric 6:
Metadata Completeness
Low
x 1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter Data
Life Cycle Stage: Use
Disposal /Treatment Method: Land
Environmental Media: Land
Release Estimation Method: TRI reporting
Annual Release Quantity (kg/yr): 2003
Number of Sites: 783
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Unacceptable
X
2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

tains TRI data directly rather than from secondary sources
Metric 4:
Temporal Representativeness
Medium
X
2
4
2001, 17 years old
Metric 5:
Sample Size
High
X
1
1
Data is industry-wide TRI data with 783 facilities reporting
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
X
1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.3.

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter Data
Life Cycle Stage: Use
Disposal /Treatment Method: POTW Transfer
Environmental Media: Water
Release Estimation Method: TRI reporting
Annual Release Quantity (kg/yr): 22,827
Number of Sites: 783
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Unacceptable
X
2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

Metric 6:
Metadata Completeness
Low
X
1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.3.

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Source Citation: U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Disposal /Treatment Method:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Other Transfers
TRI reporting
19,157,999
783
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EPA source
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Unacceptable
X
2
8
Release data from historical (pre-2000) TRI reports, EPA ob-

Metric 6:
Metadata Completeness
Low
X
1
3
Only includes release media and amount released.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.3.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
12

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Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Use
Emissions during Use (open top and closed systems)
Unknown (assume air)
Estimated (note units are g/m2 metal surface area)
Open Top: 1.4-1.7 g/m2 (min); 22-29 g/m2 (max); 7.2-8.1 g/m2
avg;Closed systems: 0.016-0.061 g/m2 (min); 0.16-1.5 g/m2 (max);
0.031- 0.18 g/m2 avg;
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X 1
1
peer revied article, assumed to use valid methods
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
High
Unacceptable
Medium
N/A
X 1
x 2
x 2
1
8
4
N/A
US source
Life cycle analysis is out of scope using air releases to define
inhalation exposure
2005, 13 years old but the data it relies on is older.
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
LCA modeling approach is clear and well documented.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Variability and uncertainty addressed in great detail.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.0.
Continued on next page
Hellweg, S.,Demou, E.,Scheringer, M.,McKone, T. E.,Hungerbuhler, K.. 2005. Confronting workplace exposure to chemicals
with LCA: examples of trichloroethylene and perchloroethylene in metal degreasing and dry cleaning. Environmental Science
and Technology.
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
88147
13

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— continued from previous page
Source Citation:	Hellweg, S.,Demou, E.,Scheringer, M.,McKone, T. E.,Hungerbuhler, K.. 2005. Confronting workplace exposure to chemicals
with LCA: examples of trichloroethylene and perchloroethylene in metal degreasing and dry cleaning. Environmental Science
and Technology.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	88147
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
14

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Source Citation: CalEpa,. 2005. Appendix D.3 Chronic RELS and toxicity summaries using the previous version of Hot Spots Risk Assessment
guidelines (OEHHA 1999).
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3982628
EXTRACTION
Parameter

Data

Life Cycle Stage:
Annual Release Quantity (kg/yr):
U se/Manufacture
CA Statewide: 176,908 lbs (1999)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Cited from CARB
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
Medium
N/A
X 1
x 2
x 2
1
8
4
N/A
US
Air releases out of scope
2000, 18 years old, but data is much older.
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Release data does not include needed metadata.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
Limited uncertainty discussion.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.5.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, two of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
15

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Source Citation: Hsia,. 2013. TSCA work plan chemicals program.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3982141
EXTRACTION
Parameter
Data
Life Cycle Stage:
Release Source:
Environmental Media:
Annual Release Quantity (kg/yr):
Number of Sites:
Use
Vapor degreasing
Air
Chart from 1988-2011:1988: 56,000,000 lbs2011: 2,600,000 lbs
Varies
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Data source not cited
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Air releases out of scope
Metric 4:
Temporal Representativeness
High
x 2
2
Provides data from 1998 to 2010
Metric 5:
Sample Size
Medium
x 1
2
Distribution of exposures across years, but no characterization
within each year.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low x 1
3
Only provides release media
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Report does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.4.

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Source Citation: D. O. W. Deutschland. 2014. Chemical safety report: Use of trichloroethylene in industrial parts cleaning by vapour degreasing
in closed systems where specific requirements (system of use-parameters) exist.
Type of Data Source Releases to the Environment; Published Models for Exposures or Releases;
Hero ID 3970823
EXTRACTION
Parameter Data
Life Cycle Stage:
Use
Release Source:
Vap<
Environmental Media:
Air,
Release or Emission Factor:
Air:
Release Estimation Method:
Air:
Daily Release Quantity (kg/day):
Air:
Annual Release Quantity (kg/yr):
Air:
Number of Sites:
9
or degreasing
Water, Soil
5.97 percent Water: 5 percent Soil: 5 percent
based on the finding of the PhD thesis from Julia von Grote (2003).
.4 kg/dWater: .335 kg/dSoil: N/A
167 kgWater: 200 kgSoil: 168 kg
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 Releases assessed using EU ERC model, expected to be accu-
rate
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Germany (OECD)
Metric 3: Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4: Temporal Representativeness
High
X
2
2
Date of model not given, but source is from 2014
Metric 5: Sample Size
N/A

N/A
N/A - modeled releases
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Low
X
1
3
Model inputs, equations, and basis not given
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
High

1.6

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Source Citation: Echa,. 2004. Summary risk assessment report: Trichloroethylene.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970815
EXTRACTION
Parameter
Data

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Manufacture
Production
Air, Water
Estimation
214
Many

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X
1
1
EU report
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
Medium
Low
X
X
X
X
1
2
2
1
2
2
4
3
EU (OECD)
Workplace that utilizes TCE
Report is from 2004, but date of data unknown
Single value given for local, regional, and continental releases,
no discussion of statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
X
1
4
Report does not document methods, sources, or assumptions
estimate releases
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
Unacceptable

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Manufacture
Intermediate Use
Air, Water
Estimation
68
Many

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Handling
Air, Water
Estimation
627
Many

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
1
EU report
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
EU (OECD)
Workplace that utilizes TCE
Report is from 2004, but date of data unknown
Single value given for local, regional, and continental releases,
no discussion of statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Report does not document methods, sources, or assumptions
estimate releases
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed.
Overall Quality Determination^
Unacceptable

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Metal Degreasing
Air, Water
Estimation
98083
Many

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Adhesives Formulation
Air, Water
Estimation
406
Many

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Adhesives Use
Air, Water
Estimation
17088
Many

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Consumer Product Formulation
Air, Water
Estimation
285
Many

Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Daily Release Quantity (kg/day):
Number of Sites:
Use
Consumer Use
Air, Water
Estimation
10523
Many

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Source Citation:	2014. Exposure scenario: Use: Trichloroethylene as an extraction solvent for removal of process oil and formation of the
porous structure in polyethylene based separators used in lead-acid batteries.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3970806
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
Release Days per Year:
Number of Sites:
Use
Carbon bed discharge stack, oil coalescing filter discharge stacks, dust
bag houses and many potential fugitive sources.
Air, Water
Air: 0.037 percent Water: 0.0000031 percent Soil: 0 percent
Estimation
41,878 kg/yr with potential to be 112,725,000 kg/yr worst case scenario.
365
1
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Releases based on mass balance, expected to be accurate and
cover all releases
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
EU(OECD)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
X
2
2
2014, 4 years old
Metric 5:
Sample Size
Low
X
1
3
Single value, no statistics given
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
All metadata given
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
High


1.6

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
26

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Feistritz Microporous, gmbh. 2014. Chemical safety report: Trichloroethylene used as degreasing solvent in the manufacture
of polyethylene separators for lead-acid batteries.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3970808
EXTRACTION
Parameter
Data

Life Cycle Stage:
Release Source:
Environmental Media:
Release or Emission Factor:
Annual Release Quantity (kg/yr):
Use
Various
Air
48.68 percent
12170 kg/yr

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
X
1
3
Not described (information redacted)
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
Unacceptable
High
Medium
X
X
X
X
1
2
2
1
2
8
2
2
EU
Air releases out of scope
No date listed, but monitoring data was taken from 2014
Provides one data point of an annual relase value to air for
2014.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
X
1
3
Only provides release media
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Report does not address variability or uncertainty
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.6.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Wu, C.,Schaum, J.. 2000. Exposure assessment of trichloroethylene. Environmental Health Perspectives.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 724225
EXTRACTION
Parameter Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Annual Release Quantity (kg/yr)
Number of Sites:
Use
Various
Fugitive, stack air releases, surface water releases, underground injection,
land disposal, and POTW transfers
Air, Water, Soil
Data from 1987-1994 broken out by year into disposal method. Ex.
1987, in lbs/yr:Fugitive: 25,978,879Stack air releases: 29,436,952Sur-
face water releases: 30,104Underground injection: 18,720Land disposal:
56,733POTW transfers: 130,178
681-959
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Data from US EPA
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Low
x 2
6
2000, 18 years old, but data is much older.
Metric 5:
Sample Size
Medium
x 1
2
Moderately well characterized
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Minimal Metadata present.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed.
Overall Quality Determination^ Medium 2.0
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
28

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: McCulloch, A.,Midgley, P. M.. 1996. The production and global distribution of emissions of trichloroethene, tetrachloroethene
and dichloromethane over the period 1988" 1992. Atmospheric Environment.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3026800
EXTRACTION
Parameter
Data
Life Cycle Stage:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Global Emissions
Air
Discussed, but not named.
197,000 - 260,000 metric tonsData broken out by region and year.
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Process explained and cited.
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Unacceptable
Low
High
X 1
x 2
x 2
x 1
2
8
6
1
Europe
Air releases out of scope
1995, 23 years old
Provides global emissions broken down by region and year.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Alludes to emisssions to air, but does not specifically state.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Discusses uncertainty and provides a potential variance per-
centage of +/- 5
Overall Quality Determination^
Unacceptable
4 Metric Mean Score: 2.7.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, two of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
29

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 1980. Waste solvent reclamation.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3840001
EXTRACTION
Parameter Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Days per Year:
Waste Treatment Method:
P2 Control & percent Efficiency:
Waste Solvent Reclamation
Fugitive, process, storage
distillation, purification
Air, water
Many sources in process cited. Example:Storage tank vent: 0.01 kg/
MgFugitive Emissions: 0.46 kg/Mg
Continuous
Recycling and recovery
40-99 percent recovery
EVALUATION

Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1 2
Well cited, well detailed, but looks to be extracted from a book
or manual with no attributes/citation.
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 No Comment.
High X 2 2 Recycling process for solvents such as TCE.
Low X 2 6 Unknown
Low X 1 3 N/a
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High x 1 1 Complete metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 No Comment.
Overall Quality Determination^
Medium
2.1

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
2017. Pollution prevention search results, envirofacts database.
Type of Data Source
Releases to the Environment; Environmental Release Data;
Hero ID
3860453
EXTRACTION

Parameter
Data
Life Cycle Stage: Use/Manufacture
Release Source: Many
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
US EPA Envirofacts
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Geographic Scope
Applicability
Temporal Representativeness
High
High
High
X 1
x 2
x 2
1
2
2
US
Releases of TCE from facilities that use TCE
Spans multiple years, majority coming from 2008 or more re-
cent.
Metric 5: Sample Size High X 1 1 site-specific releases given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable x 1
4
No metadata given, including media of release
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Not addressed.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.6.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
U.S, E. P. A.. 1995. Environmental research brief: Pollution prevention assessment for a manufacturer of locking devices.
Releases to the Environment; Environmental Release Data;
3970197
EXTRACTION
Parameter
Data
Life Cycle Stage:
Disposal /Treatment Method:
Annual Release Quantity (kg/yr)
Release Days per Year:
Number of Sites:
Waste Treatment Method:
Waste solvent
Shipped offsite for disposal
28700 lb/yr
1
1
Offsite disposal
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
US EPA
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Low
Low
X 1
x 2
x 2
x 1
1
2
6
3
US
Waste releases from a degreaser using TCE
1995, 23 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Does not include citations
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No Comment.
Overall Quality Determination^
Medium

2.1

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
32

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2014. Exposure assessment: Trichloroethylene.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3970837
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Daily Release Quantity (kg/day):
Annual Release Quantity (kg/yr):
Release Days per Year:
Number of Sites:
Use
Fugitive emissions
ambient air, water
air, water
Water: 0.01 percent Air: 60 percent
Water: 0.002 kg/day Air: 12 kg/day
Water: 0.3 kg/yrair: 1800 kg/yr
180
1
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
x 1
3	Unknown author, reads as if it is written by a manufacturer
about their own process.
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
High x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
EU
Facility using small amounts of TCE in pharmaceutical pro-
ductions.
2014, 4 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	Medium x 1	2 Includes most metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 No Comment.
Overall Quality Determination^
Medium
1.8

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
33

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: 2014. Exposure assessment: Trichloroethylene, Part 3.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3970842
EXTRACTION
Parameter Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Daily Release Quantity (kg/day):
Annual Release Quantity (kg/yr):
Release Days per Year:
Number of Sites:
Use
Fugitive emissions
ambient air, water
air, water
Air: 4.38 percent
Air 157.7 kg/day
Air: 1752 kg/yr
64 daysl6 batches @ 4 days per batch
1
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
x 1
Unknown author, reads as if it is written by a manufacturer
about their own process.
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
High x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Medium x 1
2 EU
2 Facility using TCE in the synthesis of vulcanization accelerat-
ing agents.
2 2014, 4 years old
2 No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2 Includes most metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 No Comment.
Overall Quality Determination^
Medium
1.8

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Japanese Ministry of, Environment. 2004. Manual for PRTR release estimation models: Part II materials.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3986511
EXTRACTION

Parameter
Data

Life Cycle Stage:
U se/Manufacture

Release Source:
Manufacture, storage, solvent
use, cleaning
Environmental Media:
Atmosphere

Release or Emission Factor:
Manufacture: 0.001 kg/tStorage: 0.23 kg/tSolvent: 979 kg/tCleaning:

838 kg/t

EVALUATION

Domain Metric
Rating MWF*
Score
Comments
Domain 1: Reliability

Metric 1: Methodology
Low X 1
3
not specified
Domain 2: Representative

Metric 2: Geographic Scope
Medium x 1
2
Japan
Metric 3: Applicability
Unacceptable x 2
8
Air releases out of scope
Metric 4: Temporal Representativeness
Low x 2
6
1996, 22 years old
Metric 5: Sample Size
N/A
N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Low x 1
3
Unclear how the given data source is utilized or found.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low x 1
3
Report does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 3.1.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
35

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2014. Toxic release inventory: Trichloroethylene.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3860483
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Annual Release Quantity (kg/yr)
Use/Manufacture
Landfill, Fugitive and Point Source Emissions, Surface Water, and Other
Landfill, other
Air, Water, Ground
Landfill: 16,697 lbsFugitive Emissions: 1,202,177 lbsPoint Source Emis-
sions: 779,765 lbs Surface Water: 14,406 lbsOther: 24,205 lbs
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
EPA
Domain 2: Representative





Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Medium
x 2
4
Industry that works with TCE, but is focused on industry -





wide big picture.
Metric 4:
Temporal Representativeness
High
x 2
2
2016, 2 years old
Metric 5:
Sample Size
Low
x 1
3
Not well characterized
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Low
x 1
3
No Comment.
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No Comment.
Overall Quality Determination^
Medium

1.9


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
36

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Landmeyer, J. E.,Miller, S.,Campbell, B. G.,Vroblesky, D.,Gill, A.,Clark, A. P.. 2011. Investigation of the potential source
area, contamination pathway, and probable release history of chlorinated-solvent-contaminated groundwater at the Capital
City Plume Site, Montgomery, Alabama, 2008-2010.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2129107
EXTRACTION
Parameter Data
Life Cycle Stage: Study
Release Source: Post Emission Study
Disposal /Treatment Method: sewer
Environmental Media: ground and groundwater
EVALUATION

Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1 1 USGS

Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
us
Metric 3:
Applicability
Unacceptable
X
2
8
Report details attempt to find the source of a contamination
plume, Does not contain applicable occupational scenario.
Metric 4:
Temporal Representativeness
High
X
2
2
2010
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Study is well documented and process is explained.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Report does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.0.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter Data
Ballinger, M. Y.,Larson, T. V.. 2014. Source apportionment of stack emissions from research and development facilities using
positive matrix factorization. Atmospheric Environment.
Releases to the Environment; Environmental Release Data;
2517711
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Processing
R&D Facilities
stack air
Atmosphere
EVALUATION

Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1 1 Journal article

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High x 1
Unacceptable x 2
High
Low
x 2
x 1
1 us
8 Report details use of positive matrix factorization to identify
the contributing sources to stack emissions. Air releases are
out of scope.
2 2014, 4 years old
3 Qualitative data as ratios.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Study is well documented and method is explained.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Report does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.1.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Yang, J.,Wang, K.,Zhao, Q.,Huang, L.,Yuan, C. S.,Chen, W. H.,Yang, W. B.. 2014. Underestimated public health risks
caused by overestimated VOC removal in wastewater treatment processes. Environmental Science: Processes & Impacts.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 2544474
EXTRACTION
Parameter Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release
Publicly owned treatment works (POTW)
Screen, aerated grit chamber, primary clarifier, anaerobic tank, anterior
oxic tank, secondary clarifier
Air, water
Concentrations found during treatment:0.55 ug/m3 airl.5 mg/L water
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Journal article
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Low
Low
X 1
x 2
3
6
China
Unknown occupational scenario, but potentially useful release
Metric 4:
Metric 5:
Temporal Representativeness
Sample Size
High
High
x 2
x 1
2
1
2017
Samples fully characterized and taken in multiple seasons.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Samples fully characterized and taken in multiple seasons.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
Limited variability discussion.
Overall Quality Determination^ Medium 1.8
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
39

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter Data
Chang, C. C.,Lo, G. G.,Tsai, C. H.,Wang, J. L.. 2001. Concentration variability of halocarbons over an electronics industrial
park and its implication in compliance with the Montreal protocol. Environmental Science and Technology.
Releases to the Environment; Environmental Release Data;
2773680
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Processing
Solvent use in semiconductor, circuit chip and circuit board manufacture.
Venting
Air
Median concentration:40 PPTV TCE in July 2000200 PPTV TCE in
March 1997
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Journal article
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Unacceptable
Medium
Medium
X 1
x 2
x 2
x 1
3
8
4
2
Taiwan
Air releases out of scope
2001
Many samples taken from a broad cross-section of land.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Data not well characterized, provides qualitative descriptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Report does not address variability or uncertainty
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.6.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
40

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Chen, W. H.,Yang, W. B.,Yuan, C. S.,Yang, J. C.,Zhao, Q. L.. 2014. Fates of chlorinated volatile organic compounds in
aerobic biological treatment processes: the effects of aeration and sludge addition. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2799543
EXTRACTION

Parameter
Data

Life Cycle Stage:
Study

Release Source:
air from WWTP

Environmental Media:
Air

EVALUATION

Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1: Methodology
High
X 1
1
Journal article
Domain 2: Representative

Metric 2: Geographic Scope
Low
X 1
3
China
Metric 3: Applicability
Unacceptable
x 2
8
Studies removal of TCE from wastewater, out of scope for en-

gineering
Metric 4: Temporal Representativeness
High
x 2
2
2013, 5 years old
Metric 5: Sample Size
Medium
x 1
2
Only one site was used for the study, data collected not fully

characterized
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
x 1
1
Study is well documented and method is explained.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
x 1
3
Variability and uncertainty is not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.2.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Devinny, J. S.,Webster, T. S.,Torres, E.,Basrai, S.. 1995. Biofiltration for removal of PCE and TCE vapors from contaminated
air. Hazardous Waste and Hazardous Materials.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2803108
EXTRACTION
Parameter
Data
Life Cycle Stage:
Release Source:
Environmental Media:
Study
air from WWTP
Air
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Journal article
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Studies method for removing TCE from air streams, air re-

leases out of scope
Metric 4:
Temporal Representativeness
Low
x 2
6
1995, 23 years old
Metric 5:
Sample Size
Medium
x 1
2
Study used bench scale biofilters to study
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Study is well documented and method is explained.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
Limited discussion on the variability and uncertainty in the
study.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Baek, S. 0.,Suvarapu, L. N.,Seo, Y. K.. 2015. Occurrence and Concentrations of Toxic VOCs in the Ambient Air of Gumi,
an Electronics-Industrial City in Korea. Sensors.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3001564
EXTRACTION
Parameter

Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Number of Sites:

Processing
Solvent use in semiconductor, circuit chip and circuit board manufacture.
Venting
Air
53.8 tons/yr in 2009
1428
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Domain 1: Reliability
Metric 1:
Methodology
High X 1 1 Journal article
Domain 2: Representative
Metric 2: Geographic Scope
Low
X
1
3
Korea
Metric 3: Applicability
Unacceptable
X
2
8
Air releases out of scope
Metric 4: Temporal Representativeness
High
X
2
2
2014
Metric 5: Sample Size
High
X
1
1
Large sample size across many sites.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
Study is well documented and method is explained. Data sets

are well characterized..
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
Variability and uncertainty is not addressed.
Overall Quality Determination^
Unacceptable

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Whittaker, S. G.,Taylor, J.,Van Hooser, L. M.. 2015. Characterization of "Hydrocarbon" Dry Cleaning in King
County, Washington. Journal of Environmental Health.
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
3488855
EXTRACTION
Parameter

Data
Life Cycle Stage:
Release Source:

Use
Dry Cleaning
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Journal article
Domain 2:
Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
High
Medium
x 1 1 US
X 2 8 Covers waste designations at dry cleaners, water releases not
addressed, all other releases out of scope. TCE not addressed
qunatitatively.
X 2 2 2017, 1 year old
X 1 2 Questionaire pulled results from a representative sample size,
but does not address samples in a quantitative fashion.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Study is well documented and method is explained. Data sets
are well characterized..
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Variability and uncertainty is not addressed.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.0.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Den, W.,Huang, C.,Li, C. H.. 2004. Effects of cross-substrate interaction on biotrickling filtration for the control of VOC
emissions. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3570982
EXTRACTION
Parameter

Data

Life Cycle Stage:
Release Source:
Environmental Media:

Study
VOC waste air
air
emissions in gas-phase biological processes
EVALUATION
Domain
Metric
Rating
MWF*
Score Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1 Journal article
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Geographic Scope
Applicability
Temporal Representativeness
Low
Unacceptable
Medium
X 1
x 2
x 2
3 China
8 Studies method for controlling air emissings, air releases out of
scope
4 2004, 14 years old
Metric 5: Sample Size High X 1 1 Experimental results are well characterized and described.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Study is well documented and method is explained. Data sets
are well characterized..
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Variability and uncertainty is not addressed.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Oecd,. 2009. Emission scenario document on adhesive formulation.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3827299
EXTRACTION
Parameter	Data
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
OECD document
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
High
N/A
X 1
x 2
x 2
1
2
2
N/A
US and others
ESD, not specific to TCE but includes information relevant to
TCE
Less than 10 years old
N/A - ESD
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
All metadata given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
Variability addressed through different application methods,
uncertainty not addressed
Overall Quality Determination^
High

1.1


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
46

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Oecd,. 2009. Emission scenario documents on coating industry (paints, lacquers and varnishes).
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3827298
EXTRACTION
Parameter	Data
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
OECD document
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
High
N/A
X 1
x 2
x 2
1
2
2
N/A
US and others
ESD, not specific to TCE but includes information relevant to
TCE
Less than 10 years old
N/A - ESD
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
All metadata given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
Variability addressed through different application methods,
uncertainty not addressed
Overall Quality Determination^
High

1.1


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
47

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
U.S, E. P. A.. 1995. Guidance document for the halogenated solvent cleaner NESHAP.
Type of Data Source
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID
3827323
EXTRACTION

Parameter
Data
Life Cycle Stage: EPA Guidance Document
Release Source: Halogenated Solvent Cleaner users
Disposal /Treatment Method: For compliance with NESHAP
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
EPA
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
Low
N/A
X 1
x 2
x 2
1
8
6
N/A
US
NESHAP covers air emissions, air releases out of scope
1995, 23 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Detailed data and includes test methods. Does not cite any
sources, but type of docment is not expected to.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
Unacceptable

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Carex, Canada. 2008. Priority occupational carcinogens for surveillance in Canada: Preliminary Priority List.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3978369
EXTRACTION
Parameter

Data

Life Cycle Stage:

Country-scale Releases

EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Not specified
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Medium
Medium
Low
X 1
x 2
x 2
x 1
2
4
4
3
Canada (OECD)
country wide release
2006, 12 years old
Single value, no statistics given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
media of release not given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.6.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 1977. Control of volatile organic emissions from solvent metal cleaning.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3827321
EXTRACTION
Parameter Data
Life Cycle Stage: EPA Guidance Document
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
EPA document
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
Low
N/A
X
X
X
1
2
2
1
8
6
N/A
US
Covers control of air releases, air releases out of scope
1977, 41 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Detailed data and includes test methods. Does not cite any
sources, but type of docment is not expected to.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
Unacceptable

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	U.S, E. P. A.. 2001. Guide to industrial assessments for pollution prevention and energy efficiency.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3827322
EXTRACTION
Parameter	Data
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
EPA document
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
N/A
X 1
x 2
x 2
1
2
4
N/A
US
Information for in scope uses
data from 2001 (less than 20 years but older than 10)
N/A - only qualitative information provided
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Results provided but underlying data sources not clearly de-
scribed
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed.
Overall Quality Determination^
Medium

1.8


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S. Environmental Protection Agency. 2011. The 2011 National Emissions Inventory.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 5352399
EXTRACTION
Parameter

Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release or Emission Factor:
Release Days per Year:
P2 Control & percent Efficiency:

All
Provides unit/process of release.
Provides media of release
Provides release data
Provides annual operating time.
Provides controls information.
EVALUATION

Domain
Metric
Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology
Medium X 1 2 Submitters provide general method used to calculate emissions,
but details not provided.
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
NEI is U.S. based data
Metric 3:
Applicability
High
X
2
2
NEI includes industries included in the scopes of TCE.
Metric 4:
Temporal Representativeness
High
X
2
2
NEI data are from 2011
Metric 5:
Sample Size
Medium
X
1
2
Universe is limited to units subject to NESHAP with threshold
potential to emit, although states may have different require-
ments; statistical representativeness is unclear.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 NEI includes release media and generally also includes daily
and annual operating time, specific unit/process that is the
source of release, and presence of engineering controls.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3 NEI does not address variability or uncertainty in submitter
provided data.
Overall Quality Determination^
High

1.4

-------
PEER REVIEW DRAFT
Occupational Exposure
DO NOT CITE OR QUOTE
53

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Kilburn, K. H.. 1999. Neurobehavioral and respiratory findings in jet engine repair workers: a comparison of exposed and
unexposed volunteers. Environmental Research.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1576
EXTRACTION
Parameter	Data
Life Cycle Stage:	Use
Route of Exposure:	Inhalation
Exposure Concentration (Unit):	4800 (mg/m3)
Number of Sites:	1
Type of Measurement or Method:	8-hr TWA
Number of Workers:	6
Type of Sampling:	area
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	Low	x 1	3 Not specified
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US (1 site in OK)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1993), but after PEL
Metric 5:
Sample Size
Low
X
1
3
single data point given for 6 workers, unclear what the data
represents (e.g., mean, median, etc.)
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Data indicates "area" sample but no other metadata given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^	Medium	2.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
54

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nakatsuka, H.,Watanabe, T.,Takeuchi, Y.,Hisanaga, N.,Shibata, E.,Suzuki, H.,Huang, M. Y.,Chen, Z.,Qu, Q. S.,Ikeda, M..
1992. Absence of blue-yellow color vision loss among workers exposed to toluene or tetrachloroethylene, mostly at levels below
occupational exposure limits. International Archives of Occupational and Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	58349
EXTRACTION
Parameter	Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
vapor
Inhalation
6.1-11.8 (ppm)
TWA
23 (14 men; 9 women)
personal breathing zone air samples
unknown
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	Low	X 1	3 Described as "diffusive sampling" but otherwise not described
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Japan
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1990), but after PEL
Metric 5:
Sample Size
Medium
X
1
2
geometric mean and standard deviation given, but range and
discrete sample values not provided
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Data indicates PBZ samples but other metadata not given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed with respect to exposure data
Overall Quality Determination^	Medium	2.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
55

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nagaya, T.,Ishikawa, N.,Hata, H.. 1989. Urinary total protein and "beta"-2-microglobulin in workers exposed to trichloroethy-
lene. Environmental Research.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	61122
EXTRACTION
Parameter	Data
Life Cycle Stage:	Use
Route of Exposure:	Inhalation
Exposure Concentration (Unit):	15 (ppm)
Number of Samples:	104
Type of Sampling:	urinealysis
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Sources documented, but not from frequently used source
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Low
N/A
X 1
x 2
x 2
2
2
6
N/A
Japan (OECD)
Workplace that utilizes TCE
Prior to 1988
N/A - information about use of TCE in semiconductor manu-
facturing, no quantitative data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Sources clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
56

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Stewart, P. A.,Lee, J. S.,Marano, D. E.,Spirtas, R.,Forbes, C. D.,Blair, A.. 1991. Retrospective cohort mortality study of
workers at an aircraft maintenance facility: II. Exposures and their assessment. British Journal of Industrial Medicine.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 65131
EXTRACTION
Parameter
Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Workers:
Type of Sampling:
Use
600 ppm (1939-1954)400 ppm (1955-1967)200 ppm (1968-1978)0 ppm
(1979-1983)
7282 (over 1939-1982)
Estimation
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
x 1
2
Peer-reviewed article, using data not from a frequently used
source
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Low
N/A
X 1
x 2
x 2
1
2
6
N/A
US
Workplace that utilizes TCE
Data from 1939-1983 (older than 20 years)
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Metadata associated with exposure indices used to estimate
exposure not provided
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable
Metric Mean Score: 2.2.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
57

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Landrigan, P. J.,Stein, G. F.,Kominsky, J. R.,Ruhe, R. L.,Watanabe, A. S.. 1987. Common-source community and industrial
exposure to trichloroethylene. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 65261
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Use
vapor
Inhalation
117-357 (mg/m3)
1
8-hr TWA
degreasing using open-top liquid-vapor degreader with refirgerated free-
board chiller and at cold degreasers
at least 10
personal breathing zone air samples
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 Method described and appears to be equivalent to NIOSH
methods
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US data
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1980), but after PEL
Metric 5:
Sample Size
Medium
X
1
2
Range of results given, but discrete data and other statistics
not given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Critical metadata given but missing sample durations and ex-
posure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness Low X 1 3 Not addressed with respect to exposure data
Continued on next page
58

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Landrigan, P. J.,Stein, G. F.,Kominsky, J. R.,Ruhe, R. L.,Watanabe, A. S.. 1987. Common-source community and industrial
exposure to trichloroethylene. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	65261
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

Medium 1.7


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
59

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Landrigan, P. J.,Stein, G. F.,Kominsky, J. R.,Ruhe, R. L.,Watanabe, A. S.. 1987. Common-source community and industrial
exposure to trichloroethylene. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 65261
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Use
vapor
Inhalation
37-144 (mg/m3)
1
8-hr TWA
degreasing using open-top liquid-vapor degreader with refirgerated free-
board chiller and at cold degreasers
at least 10
personal breathing zone air samples
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Method described and appears to be equivalent to NIOSH
methods
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
Medium
X 1
x 2
x 2
x 1
1
2
4
2
US data
Workplace that utilizes TCE
Data older than 10 years (1980), but after PEL
Range of results given, but discrete data and other statistics
not given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Critical metadata given but missing sample durations and ex-
posure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
Not addressed with respect to exposure data
Continued on next page
60

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Landrigan, P. J.,Stein, G. F.,Kominsky, J. R.,Ruhe, R. L.,Watanabe, A. S.. 1987. Common-source community and industrial
exposure to trichloroethylene. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	65261
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

Medium 1.7


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
61

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Occupational Exposure; Monitoring Data;
35002
EXTRACTION





Parameter

Data



Life Cycle Stage:

Use



Route of Exposure:

Inhalation



Exposure Concentration (Un
t):
1.2-5.1 (pp
m)


Number of Sites:

23225



Number of Workers:

401000



Type of Sampling:

survey



EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Low
x 1
3
Unknown testing methods
Domain 2: Representative





Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years but after PEL
Metric 5:
Sample Size
Medium
x 1
2
Only range provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure and sample type given
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
62

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
U.S, E. P. A.. 2001. Sources, emission and exposure for trichloroethylene (TCE) and related chemicals.
Occupational Exposure; Monitoring Data;
35002
EXTRACTION
Parameter
Data
Life Cycle Stage:
Route of Exposure:
Exposure Concentration (Unit):
Type of Sampling:
Use
Inhalation
1-100 (ppm)
survey
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Low
X 1
3
Unknown testing methods
Domain 2: Representative





Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years but after PEL
Metric 5:
Sample Size
Medium
x 1
2
Only range provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure and sample type given
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
63

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Ruijten, M. W.,Verberk, M. M.,SallA©, H. J.. 1991. Nerve function in workers with long term exposure to trichloroethene.
British Journal of Industrial Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 65298
EXTRACTION
Parameter

Data

Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Sampling:
Use
80 (ppm)
100
1
area

EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X
1
3
Not described other than sampling using gas detection tube
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Low
Medium
X
X
X
X
1
2
2
1
2
2
6
2
Study from Netherlands (OECD)
Workplace that utilizes TCE
Data collected prior to PEL (1966)
Means given but no other statisics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
X
1
4
No metadata provided
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Not addressed with respect to exposure data
Overall Quality Determination^
Unacceptable

Data

Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Sampling:
Use
70 (ppm)
90
1
area

EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X
1
3
Not described other than sampling using gas detection tube
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Medium
X
X
X
X
1
2
2
1
2
2
4
2
Study from Netherlands (OECD)
Workplace that utilizes TCE
Data older than 10 years (1976) but after PEL
Means given but no other statisics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
X
1
4
No metadata provided
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Not addressed with respect to exposure data
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.2.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
65

Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Sampling:
Engineering Control & percent Exposure Reduction:
Use
35 (ppm)
not provided
1
area
Local exhaust installed

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
X 1
3
Not described other than sampling using gas detection tube
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
Medium
Medium
X 1
x 2
x 2
x 1
2
2
4
2
Study from Netherlands (OECD)
Workplace that utilizes TCE
Data older than 10 years (1976) but after PEL
Means given but no other statisics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
No metadata provided
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed with respect to exposure data
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.2.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
66

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ulander, A.,Selden, A.,Ahlborg, G., Jr.. 1992. Assessment of intermittent trichloroethylene exposure in vapor degreasing.
AIHA Journal.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	67506
EXTRACTION





Parameter

Data



Life Cycle Stage:

Use



Exposure Concentration (Un
t):
3-144 (mg
/m3); 16
mg/m3 median
Number of Samples:

not provided


Number of Sites:

19



Number of Workers:

31



Type of Sampling:

personal breathing
zone
air samples
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Medium
X 1
2
Method described and appears to be acceptable (peer reviewed





journal)
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Study from Sweden (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1988-1989) but after PEL
Metric 5:
Sample Size
Medium
x 1
2
Median, mean, and range given, but discrete data not available
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Low
x 1
3
Indicates PBZ and full-shift exposure values but sample dura-





tion, exposure duration, exposure frequency not given
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Medium
x 1
2
Limited characterization of uncertainty/variability.
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
67

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Skender, L. J.,Karacic, V.,Prpic-Majic, D.. 1991. A comparative study of human levels of trichloroethylene and tetra-
chloroethylene after occupational exposure. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	69136
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Use
25-40 (mg/m3)
not provided
4
10
personal breathing zone air samples
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Medium
X
1
2
Method described and appears to be acceptable (peer reviewed






journal)
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europen study (EU countries are part of OECD)
Metric 3:
Applicability
Unacceptable
X
2
8
Data for use of TCE as a dry cleaning solvent, not a US use






(spot cleaning only)
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1990) but after PEL
Metric 5:
Sample Size
Medium
X
1
2
range given but no other statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Unacceptable
X
1
4
No metadata given
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Unacceptable


4
Metric Mean Score: 2.8.
Continued on next page
68

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Skender, L. J.,Karacic, V.,Prpic-Majic, D.. 1991. A comparative study of human levels of trichloroethylene and tetra-
chloroethylene after occupational exposure. Archives of Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	69136
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, two of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
69

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ikeda, M.. 1977. Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environmental Health Perspec-
tives.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75160
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Exposure Frequency:
Use
10-170 (ppm)
not provided
10
12
area
2-4 hrs
1-2/month
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Japan (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1977) but after PEL
Metric 5:
Sample Size
Medium
x 1
2
range given but no other statistics
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Medium
x 1
2
Only exposure type and duration given
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
70

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ikeda, M.. 1977. Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environmental Health Perspec-
tives.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75160
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
200 (ppm)
not provided
10
6
area
Intermittent exp over 8hr/day
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Medium
X 1
x 2
x 2
x 1
2
2
4
2
Japan (OECD)
Workplace that utilizes TCE
Data older than 10 years (1977) but after PEL
range given but no other statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Only exposure type and duration given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
71

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ikeda, M.. 1977. Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environmental Health Perspec-
tives.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75160
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Exposure Frequency:
Use
20-40 (ppm)
not provided
10
6
area
8 hr/day
5 days/week
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Japan (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1977) but after PEL
Metric 5:
Sample Size
Medium
x 1
2
range given but no other statistics
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Medium
x 1
2
Only exposure type and duration given
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
72

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ikeda, M.. 1977. Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environmental Health Perspec-
tives.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75160
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
50 (ppm)
not provided
10
6
area
Intermittent exp over 8hr/day
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Medium
X 1
x 2
x 2
x 1
2
2
4
2
Japan (OECD)
Workplace that utilizes TCE
Data older than 10 years (1977) but after PEL
range given but no other statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Only exposure type and duration given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
73

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Inoue, 0.,Seiji, K.,Kawai, T.,Jin, C.,Liu, Y. T.,Chen, Z.,Cai, S. X.,Yin, S. N.,Li, G. L.,Nakasutka, H.,Watanabe, T.,Ikeda, M..
1989. Relationship between vapor exposure and urinary metabolite excretion among workers exposed to trichloroethylene.
American Journal of Industrial Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75359
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Manufacturing
3-94 (ppm) men; 2-47 (ppm) women
not provided
1
61 (men); 17 women
personal
3 x 8 hr shifts
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Medium
X
1
2
Method described and appears to be acceptable (peer reviewed






journal)
Domain 2: Representative






Metric 2:
Geographic Scope
Low
X
1
3
China (non-OECD)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1989) but after PEL
Metric 5:
Sample Size
Medium
X
1
2
range given but no other statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Low
X
1
3
Only sample type (PBZ) given
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^	Medium	2.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
74

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Inoue, 0.,Seiji, K.,Kawai, T.,Jin, C.,Liu, Y. T.,Chen, Z.,Cai, S. X.,Yin, S. N.,Li, G. L.,Nakasutka, H.,Watanabe, T.,Ikeda, M..
1989. Relationship between vapor exposure and urinary metabolite excretion among workers exposed to trichloroethylene.
American Journal of Industrial Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75359
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
1-63 (ppm) men; 2-13 (ppm) women
not provided
1
52 (men); 10 women
personal
3 x 8 hr shifts
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Medium
X
1
2
Method described and appears to be acceptable (peer reviewed






journal)
Domain 2: Representative






Metric 2:
Geographic Scope
Low
X
1
3
China (non-OECD)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1989) but after PEL
Metric 5:
Sample Size
Medium
X
1
2
range given but no other statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Low
X
1
3
Only sample type (PBZ) given
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^	Medium	2.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
75

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ogata, M.,Kihara, T.,Kamoi, R.,Taguchi, T.,Oda, J.,Kenmotsu, K.. 1988. A report of worker suffering from pneumatosis
cystoides intestinalis following trichloroethylene exposure. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75409
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Use
32 ppm (geometric mean); 18-56 ppm (90 percent range)
not provided
1
soaking metal parts in TRI tank under ultrasonic waves to degrease;
additional acitivty - washing process for 1 minute at least 1/day exposed
to higher concentrations than general air of working environment.
1
area
5 sampling points in unit work area
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Method described and appears to be acceptable (peer reviewed
journal)
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Medium
X 1
x 2
x 2
x 1
2
2
4
2
Japan (OECD)
Workplace that utilizes TCE
Data older than 10 years (1988) but after PEL
range and mean given but no discrete data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Only sample type (area) given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.0

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Ogata, M.,Kihara, T.,Kamoi, R.,Taguchi, T.,Oda, J.,Kenmotsu, K.. 1988. A report of worker suffering from pneumatosis
cystoides intestinalis following trichloroethylene exposure. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75409
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
77

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Seiji, K.,Jin, C.,Watanabe, T.,Nakatsuka, H.,Ikeda, M.. 1990. Sister chromatid exchanges in peripheral lymphocytes of workers
exposed to benzene, trichloroethylene, or tetrachloroethylene, with reference to smoking habits. International Archives of
Occupational and Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75419
EXTRACTION
Parameter
Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Number of Workers:
Type of Sampling:
Mfg and Use
7 ppm (geometric mean); 13 ppm (75 percentile); 32 ppm (max)
not provided
unknown
8-hr TWA
22 (men); 16 (women)
assumed area
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Medium
X 1
2
Method described and appears to be acceptable (peer reviewed





journal)
Domain 2: Representative





Metric 2:
Geographic Scope
Low
X 1
3
Data from China (non-OECD country) and Japan (OECD





country)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1987) but after PEL
Metric 5:
Sample Size
Medium
x 1
2
Geometric mean and 75 percent -tile given, no discrete data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x
1
2
Sample type (PBZ) and exposure type given; missing worker
activities, sample duration, and exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x
1
3
Not addressed
Overall Quality Determination^
Medium

2.0


Continued on next
page


78

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— continued from previous page
Source Citation:	Seiji, K.,Jin, C.,Watanabe, T.,Nakatsuka, H.,Ikeda, M.. 1990. Sister chromatid exchanges in peripheral lymphocytes of workers
exposed to benzene, trichloroethylene, or tetrachloroethylene, with reference to smoking habits. International Archives of
Occupational and Environmental Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	75419
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
79

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Chia, S. E.,Goh, V. H.,Ong, C. N.. 1997. Endocrine profiles of male workers with exposure to trichloroethylene. American
Journal of Industrial Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 630431
EXTRACTION
Parameter Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Use
9 -131 ppm (29.6 ppm mean)
1
8-hr TWA
12
personal
various locations within the facility
8 hr shift
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Cite NIOSH method
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
High
Medium
High
X
X
X
X
1
2
2
1
3
2
4
1
Singapore (non-OECD)
Workplace that utilizes TCE
Data older than 10 years (1997) but after PEL
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
X
1
2
Sample type (PBZ) and exposure type given; missing worker
activities, sample duration, and exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Medium

1.8

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Imbriani, M.,Niu, Q.,Negri, S.,Ghittori, S.. 2001. Trichloroethylene in urine as biological exposure index. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	663955
EXTRACTION
Parameter	Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
27-387 (mg/m3); mean: 83.31 (mg/m3)
assumeed 49 based on number of workers
1
8-hr TWA
8 (men); 41 (women)
personal
8 hr shift
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1 2
Method described and appears to be acceptable (peer reviewed
journal)
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Italy (OECD)
Metric 3: Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4: Temporal Representativeness
Medium
X
2
4
Data older than 10 years (2000) but after PEL
Metric 5: Sample Size
Medium
X
1
2
Range, arithmetic mean, geometric mean, ASD, GSD all given,





no discrete samples
Domain 3: Accessibility/Clarity





Metric 6: Metadata Completeness
Medium
X
1
2
Sample type (PBZ), exposure type given, sample duration





given; missing worker activities and exposure frequency
Domain 4: Variability and Uncertainty





Metric 7: Metadata Completeness
Low
X
1
3
Not addressed with respect to exposure data
Overall Quality Determination^
Medium


1.9

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
81

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Cdc,. 1978. Health hazard evaluation report no. HETA-78-38-512: Trans World Airlines Corporation.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3994172
EXTRACTION
Parameter	Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Exposure Frequency:
PPE:
Use
Vapor
inhalation
l-7ppm
4
1
Short-term
Ultrasonic Parts Cleaning
1
Personal
Infrequent
Respirator
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High	X 1	1 Not described, but NIOSH HHE, assumed to use NIOSH
method
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1978) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	Medium x 1	2 Critical metadata present
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness	Low	x 1	3 Not addressed
Continued on next page
82

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— continued from previous page
Source Citation:	Cdc,. 1978. Health hazard evaluation report no. HETA-78-38-512: Trans World Airlines Corporation.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3994172
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
83

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Osha,. 1989. 1988 OSHA Pel Project documentation: Trichloroethyle.
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
3986441
EXTRACTION
Parameter
Data

EVALUATION

Domain
Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 OSHA documet
Domain 2: Representative
Metric 2: Geographic Scope
High
X
1
1
US
Metric 3: Applicability
Unacceptable
X
2
8
Discussion on health effects and rule making, not workplace
Metric 4: Temporal Representativeness
Low
X
2
6
1988 - 30 years old
Metric 5: Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
N/A

N/A
No Comment.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
N/A

N/A
N/a
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.7.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
84

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Source Citation:	CalEpa,. 2005. Appendix D.3 Chronic RELS and toxicity summaries using the previous version of Hot Spots Risk Assessment
guidelines (OEHHA 1999).
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3982628
EXTRACTION
Parameter	Data
Life Cycle Stage:
Manufacture
Physical Form:
Vapor
Route of Exposure:
inhalation
Exposure Concentration (Unit):
0-200 ppm
Worker Activity:
Multiple, findings from multiple occupational studies
Number of Workers:
79
Exposure Duration:
Varies
Exposure Frequency:
Varies
EVALUATION

Domain Metric
Rating MWF* Score Comments
Domain 1: Reliability

Metric 1: Methodology
Low X 1 3 Not specified
Domain 2: Representative
Metric 2:	Geographic Scope	High	x 1	1	US
Metric 3:	Applicability	High	X 2	2	Workplace that utilizes TCE
Metric 4:	Temporal Representativeness	Medium	x 2	4	2000 - 18 years old (after PEL)
Metric 5:	Sample Size	Medium	x 1	2	Only range provideds
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	Low	x 1	3 Only sample type given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed with respect to exposure data
Overall Quality Determination^
Medium
2.0

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
85

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Osha,. 2017. WTC OSHA non-asbestos sampling data for Southeast area.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3982438
EXTRACTION
Parameter	Data
Life Cycle Stage:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture/Use
inhalation
0 ppm
37
TWA
Various
Personal
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High	X 1	1 Not described, but OSHA, assumed to use OSHA method
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope	High	x 1
Applicability	Unacceptable	x 2
Temporal Representativeness	Medium	x 2
Sample Size	High	x 1
1 US
8 All TCE samples are 0 and no context given to results; there-
fore, it is unclear if TCE is being used
4 Data older than 10 years (2002) but after PEL
1	Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	Medium	x 1	2 Critical metadata present
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
Not addressed
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.2.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
86

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Doe,. 2003. A needs assessment for medical screening of construction workers at the Portsmouth and Paducah gaseous
diffusion plants.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3974976
EXTRACTION
Parameter
Data

Life Cycle Stage:
Number of Sites:
Worker Activity:
Number of Workers:
Use
2
Degreasing
>1000

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X 1
1
University of Cincinnati, NIOSH, DOE
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
High
Unacceptable
Low
N/A
X 1
x 2
x 2
1
8
6
N/A
US
Retroactive look at a workplace scenario
2003, but uses older data
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Well documented, but little to no citations inline with the text
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.6.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
87

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Niosh,. 1982. Health hazard evaluation report no. HETA-82-136-1175, U.S. Army Research Office, Research Triangle Park,
North Carolina.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3974950
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Sampling:
Sampling Location:
Bulk and Dust Particle Size Distribution:
Engineering Control & percent Exposure Reduction:
Use
Vapor
inhalation
0.75-1.34 ppm
7
1
Area, Personal
Work Table
0.35-0.56 mg/m3
Exhaust Fans,
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Not described, but NIOSH HHE, assumed to use NIOSH
method
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
Low
X 1
x 2
x 2
x 1
1
2
4
3
US
Workplace that utilizes TCE
Data older than 10 years (1982) but after PEL
Described as up to 1.34 ppm of TCE, no other sample data
given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Indicates both PBZ and area samples taken but not clear which
is applicable to the TCE value given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed



Continued on next
page


88

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— continued from previous page
Source Citation:	Niosh,. 1982. Health hazard evaluation report no. HETA-82-136-1175, U.S. Army Research Office, Research Triangle Park,
North Carolina.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3974950
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 2.0.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
89

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Seitz, T.,Driscoll, R.. 1989. Health hazard evaluation report no. HETA 88-082-1971, Jostens Incorporated, Princeton, Illinois.
Occupational Exposure; Monitoring Data;
3970562
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Engineering Control & percent Exposure Reduction:
PPE:
Analytic Method:
Use
Vapor
inhalation
14.7-33.4 ppm
15
1
TWA
Cleaning/degreasing
35
Area, Personal
Polishing and plating departments
Local exhaust ventilation
Gloves, goggles
NIOSH Method 1022
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
NIOSH Method 1022
Domain 2: Representative





Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1989) but after PEL
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
All metadata present
Domain 4: Variability and Uncertainty
Continued on next page
90

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Seitz, T.,Driscoll, R.. 1989. Health hazard evaluation report no.
Occupational Exposure; Monitoring Data;
3970562
HETA
88-082-1971, Jostens Incorporated, Princeton, Illinois.
EVALUATION
Domain
Metric
Rating MWF*
Score
Comments

Metric 7; Metadata Completeness
Medium x 1
2
None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
91

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Okawa, M. T.. 1973. Health hazard evaluation report no. HHE 72-74-51, Western Electric Company, Dublic, California.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970618
EXTRACTION
Parameter	Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Engineering Control & percent Exposure Reduction:
PPE:
Analytic Method:
Use
Vapor
inhalation
6-106 ppm
43
1
Paint spraying, cleaning, washing
Personal
Local exhaust ventilation, vent hoods
respirators
NIOSH method
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
NIOSH report
Domain 2: Representative






Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1979) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
All metadata present
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x
1
2
None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High

1.3


Continued on next
page

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Okawa, M. T.. 1973. Health hazard evaluation report no. HHE 72-74-51, Western Electric Company, Dublic, California.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970618
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation:	R. A. G. Aktiengesellschaft. 2014. Chemical safety report: Trichloroethylene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970841
EXTRACTION
Parameter	Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Worker Activity:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
2.4 - 95.5 mg/m3
2
repairing belts in coal mines
coal mine belts
<4 hours
varies
Good mine ventilation
Protective gloves, suits and eye protection
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Geographic Scope
Applicability
Temporal Representativeness
Medium
High
Medium
X 1
x 2
x 2
2
2
4
Germany (OECD)
Workplace that utilizes TCE
Data from sources from 2011 and 2005; therefore, scored based
on oldest data which is older than 10 years but after PEL
Metric 5: Sample Size
High
x 1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2 Only Sample type and exposure type give
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed
Overall Quality Determination^
Medium
1.9
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	R. A. G. Aktiengesellschaft. 2014. Chemical safety report: Trichloroethylene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970841
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
95

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Source Citation: 2014. Exposure assessment: Trichloroethylene, Part 2.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970840
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
PPE:
Analytic Method:
Use
liquid, vapor
inhalation, dermal
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— continued from previous page
Source Citation: 2014. Exposure assessment: Trichloroethylene, Part 2.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970840
EVALUATION
Domain Metric Rating MWF* Score Comments
Overall Quality Determination^ Medium 1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
97
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Source Citation: D. O. W. Deutschland. 2014. Chemical safety report: Use of trichloroethylene in industrial parts cleaning by vapour degreasing
in closed systems where specific requirements (system of use-parameters) exist.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970823
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Analytic Method:
Use
liquid, vapor
inhalation, dermal
4.61 mg/m3 - 13.69 mg/m3 (90th percentile measured data)
9941 area, 58 personal
9
8 hr TWA
Vapor degreasing
Personal, area
methodology NF X 43-267/INRS 029-01/09
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X
1
2
Methods provided, sampling completed by UKAS acreddited
lab; therefore, assumed to be acceptable
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
High
X
X
X
X
1
2
2
1
2
2
2
1
Data from UK and Prance (OECD)
Workplace that utilizes TCE
No date listed, but monitoring data was taken from 2009-2014
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
X
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
High

1.6

Continued on next
page

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— continued from previous page
Source Citation: D. O. W. Deutschland. 2014. Chemical safety report: Use of trichloroethylene in industrial parts cleaning by vapour degreasing
in closed systems where specific requirements (system of use-parameters) exist.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970823
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
99
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Source Citation: D. O. W. Deutschland. 2014. Chemical safety report: Use of trichloroethylene in packaging.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970813
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
0.0004 - 1.5 ppm
47
1
TWA
Filling Barrels and fill tank trucks and traincars.
2
personal
tank filling station, barrel filling station
8
240 d/y
Ventilation and exhause air
TCE resistant gloves, goggles
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Not specified
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
2014, 4 years old
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
x 1
1
All metadata present
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation:
Type of Data Source
Hero ID
D. O. W. Deutschland. 2014. Chemical safety report: Use of trichloroethylene in packaging.
Occupational Exposure; Monitoring Data;
3970813
EVALUATION
Domain
Metric Rating MWF* Score Comments
Metric 7: Metadata Completeness Low x 1 3 Not addressed
Overall Quality Determination^ High 1.6

personal

Sampling Location:

varies

Exposure Duration:

varies

Exposure Frequency:

365

Analytic Method:

German Technical Rule TRGS 402
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
German Technical Rule TRGS 402, assumed to be acceptable
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
2015, but utilizes monitoring data from 2013
Metric 5:
Sample Size
Low
x 1
3
unclear if sample values given are discrete samples or based on

a median, mean, etc.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation: Domo Caproleuna GmbH. 2015. Chemical safety report: Industrial use as an extractive solvent for the purification of capro-
lactam from caprolactam oil.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970812
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed

Overall Quality Determination^
Medium
1.8

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Not specified
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
No date, but samples were pulled from 2011-2014
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
x 1
1
All metadata present
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^ High 1.6
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— continued from previous page
Source Citation: D. O. W. Deutschland. 2014. Chemical safety report: Uses of trichloroethylene in formulation.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970810
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
105
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Source Citation: Domo Caproleuna GmbH. 2014. Chemical safety report: Industrial use as an extractive solvent for the purification of capro-
lactam from caprolactam oil.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970809
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Exposure Frequency:
PPE:
Analytic Method:
Use
liquid, vapor
inhalation, dermal
Inhalation: 0.4-38 mg/m3 (some estimated).Dermal:0.34-2.7 mg/kg (es-
timated).
8 hour TWA
Varies
Personal
Varies
Varies
Chem. Resistant gloves, safety glasses, safety shoes, and usual protective
clothing.
German technical rule TRGS 402
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
German Technical Rule TRGS 402, assumed to be acceptable
Domain 2: Representative

a median, mean, etc.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation: Domo Caproleuna GmbH. 2014. Chemical safety report: Industrial use as an extractive solvent for the purification of capro-
lactam from caprolactam oil.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970809
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed

Overall Quality Determination^
Medium
1.8

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Not specified
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Czech Republic (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
Samples from 2011-2013
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^ Medium 1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
108
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Source Citation: 2014. Exposure scenario: Use: Trichloroethylene as an extraction solvent for removal of process oil and formation of the
porous structure in polyethylene based separators used in lead-acid batteries.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970806
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
PPE:
Analytic Method:
Use
liquid, vapor
inhalation
Personal: 0.48-44.8 mg/m3Area: 26.7-1001 mg/m3
36
1
12 hour TWA
Varies
91
Personal, area
Multiple
10.66 hours
3.5 days/week
Respirators during certain tasks.
EN 482:2012
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Badge monitoring
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
2014, 4 years old
Metric 5:
Sample Size
Medium
x 1
2
75th percentile given, no other statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
2014. Exposure scenario: Use: Trichloroethylene as an extraction solvent for removal of process oil and formation of the
porous structure in polyethylene based separators used in lead-acid batteries.
Occupational Exposure; Monitoring Data;
3970806
EVALUATION
Domain
Metric
Rating
MWF* Score Comments
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed
Overall Quality Determination^
Medium
1.7

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Unacceptable
X
1
4
Document does not contain necessary metadata to understand

the model
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.8.
Continued on next page
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Source Citation: Chimcomplex, S. A. Borzesti. 2014. Chemical safety report: Industrial use of trichloroethylene (TCE) as a solvent as a
degreasing agent in closed systems.
Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;
Hero ID 3970803
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
112
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Source Citation: D. O. W. Deutschland. 2017. Chemical safety report: Use of trichloroethylene as extraction solvent for bitumen in asphalt
analysis.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970802
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
2.6 - 2.737 mg/m3
65 (sets of 13, averaged into one point)
1
8 hour TWA
Cleaning, TCE recovery operations, etc.
Area
Multiple
<8 hours
Varies
SAFET Tainer system
Varies
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
German Technical Rule TRGS 402, assumed to be acceptable
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
data from 2013
Metric 5:
Sample Size
Medium
x 1
2
All results indicated as less the the LOQ
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Continued on next page
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— continued from previous page
Source Citation: D. O. W. Deutschland. 2017. Chemical safety report: Use of trichloroethylene as extraction solvent for bitumen in asphalt
analysis.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970802
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed

Overall Quality Determination^
Medium
1.7

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Not specified
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
Sampling from 2014
Metric 5:
Sample Size
Medium
x 1
2
only 90th percentile given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Sample type given, but no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

1.9

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Well described, but method not cited
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU data (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
2016, 2 years old
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type, sample type, worker activities given, no other

metadata
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation: Vlisco Netherlands, B. V.. 2014. Chemical safety report Part A: Use of trichloroethylene as a solvent for the removal and
recovery of resin from dyed cloth.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970833
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed

Overall Quality Determination^
High
1.6

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
117
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Source Citation: Lewis, F. A.. 1980. Health hazard evaluation report no. HHE 80-87-708, Harowe Servo Contorls Inc., West Chester,
Pennsylvania.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970663
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Exposure Frequency:
PPE:
Use
liquid, vapor
inhalation, dermal
0.32-21 ppmTWA: 10.8-12.3 ppmCeiling:10.6 - 27.3 ppm
16
1
Short-term, 8 hour TWA
Vapor degreasing
Personal, area
Varies
Varies
Standard PPE
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 No analytical method given, but completed by NIOSH
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1980) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness Low x 1 3 Not addressed
Continued on next page
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— continued from previous page
Source Citation: Lewis, F. A.. 1980. Health hazard evaluation report no. HHE 80-87-708, Harowe Servo Contorls Inc., West Chester,
Pennsylvania.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970663
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.6

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH Method 1022
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation:
Type of Data Source
Hero ID
Hills, B. W.,Kawamoto, M. M.. 1992. Health hazard evaluation report
tive, Port Huron, Michigan.
Occupational Exposure; Monitoring Data;
3970662
no. HETA 90-029-2212; United Technologies Automo-
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Metric 7: Metadata Completeness
Medium
X 1 2
None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Vandervort, R.,Polakoff, P. L.. 1973. Health hazard evaluation report no. HHE 72-84-31, Dunham-Bush, Incroprated, West
Hartford, Connecticut, Part 2.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970657
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Use
liquid, vapor
inhalation, dermal
170-420 mg/m3
30
1
Short-term
Degresasing and assembling air conditioners
480
Personal, area
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
No analytical method given, but completed by NIOSH and
includes well described process
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1973) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2 Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed
Overall Quality Determination^
High
1.6
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Vandervort, R.,Polakoff, P. L.. 1973. Health hazard evaluation report no. HHE 72-84-31, Dunham-Bush, Incroprated, West
Hartford, Connecticut, Part 2.
Occupational Exposure; Monitoring Data;
3970657
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation: Straub, W. E.,Meyer, C.. 1977. Health hazard evaluation report no. HHE 77-3-420, Essex International, Kittaning, PA.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970655
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Use
liquid, vapor
inhalation, dermal
1-15 ppm
50
1
Short-term
Soldering, assembly of electronic chip boards
Personal, Area
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
No analytical method given, but completed by NIOSH and

includes well described process
Domain 2: Representative

Metric 6:
Metadata Completeness
Low
X
1
3
Sample type given no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Medium

1.7

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
No analytical method given, but completed by NIOSH and

includes well described process
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
2005, 13 years old (after PEL)
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
High

1.6

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
126
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Source Citation:
Type of Data Source
Hero ID
Gunter, B. J.. 1977. Health hazard evaluation report no. HHE 76-101-376, FMC Corporation, Broomfield, Colorado.
Occupational Exposure; Monitoring Data;
3970648
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
2-57 mg/m3
10
1
Degreasing, Polishing, Engraving, Painting,
Personal, area
Well Ventilated Hoods
Appropriate PPE
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
No analytical method given, but completed by NIOSH and
includes well described process
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
High
X 1
x 2
x 2
x 1
1
2
4
1
US
Workplace that utilizes TCE
Data older than 10 years (1976) but after PEL
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
127
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Source Citation: Finely, M.,Tapp, L.. 2004. Health hazard evaluation report no. HETA 2003-0029-2923, Ward Brodt Music Mall, Madison,
Wisconsin.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970649
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Exposure Duration:
Exposure Frequency:
Engineering Control & percent Exposure Reduction:
PPE:
Analytic Method:
Use
liquid, vapor
inhalation, dermal
0-.99ppm
6
1
Long term /Full Shift
Instrument Repair, various tasks
126, with 8 working with TCE
Personal, area
Short
Frequent
Local Exhaust Ventilation, Vent hoods
Gloves, eye goggles, aprons, and dustmasks.
NIOSH method 2549
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 NIOSH method 2549
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
2004, 14 years old (after PEL)
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Most metadata given, missing exposure frequency
Continued on next page
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Finely, M.,Tapp, L.. 2004. Health hazard evaluation report no. HETA 2003-0029-2923, Ward Brodt Music Mall, Madison,
Wisconsin.
Occupational Exposure; Monitoring Data;
3970649
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High 1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
NIOSH Method No 1003
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
2003, 15 years old (after PEL)
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
None discussed, but NIOSH method addresses variability/

uncertainty in the method
Continued on next page
130
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Source Citation: Burr, G.. 2003. Health hazard evaluation report no. HETA 2002-0184-2888, Aero-Classics, Ltd., Huron, Ohio.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970647
EVALUATION
Domain Metric Rating MWF* Score Comments
Overall Quality Determination^ High 1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
131
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Source Citation: Kinnes, G. M.. 1998. Health hazard evaluation report no. HETA 97-0214-2689, Dorma Door Controls, Inc., Reamstown
Pennsylvania.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970645
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Analytic Method:
Use
Vapor
inhalation
0.71 - 3.5 ppm
3
1
Partial Shift, TWA
Degreaser
Area
NIOSH Method 1022
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
NIOSH Method 1022
Domain 2: Representative

1.4

Continued on next
page

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Kinnes, G. M.. 1998. Health hazard evaluation report no. HETA 97-0214-2689, Dorma Door Controls, Inc., Reamstown
Pennsylvania.
Occupational Exposure; Monitoring Data;
3970645
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
133
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Source Citation: Gunter, B. J.,Lucas, J. B.. 1975. Health hazard evaluation report no. HHE 74-61-232, Gates Rubber Company, Denver
Colorodo.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970644
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
<.05 mg/m3
4
1
Rubber hose knitting machine
6
Personal
Knitting Station
Full shift
Not assessed.
Cannot wear gloves.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Continued on next page
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— continued from previous page
Source Citation: Gunter, B. J.,Lucas, J. B.. 1975. Health hazard evaluation report no. HHE 74-61-232, Gates Rubber Company, Denver
Colorodo.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970644
EVALUATION
Domain
Metric
Rating MWF* Score
Comments

Overall Quality Determination^

High 1.6

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH Method 1501
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Continued on next page
136
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Crandall, M. S.,Galson, S.,Hartle, R. W..
Systems, Incorporated, Ashtabula, Ohio.
Occupational Exposure; Monitoring Data;
3970640
1988. Health hazard evaluation report no. HETA 87-095-1927, G & L Recovery
EVALUATION
Domain
Metric
Rating
MWF* Score Comments

Metric 7: Metadata Completeness
Medium
X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.4

1.6

Continued on next page
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— continued from previous page
Source Citation: Gilles, D.,Philbin, E.. 1976. Health hazard evaluation report no. HHE 76-61-337, TRW Incorporated, Philadelphia, Pennsyl-
vania.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970635
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1 1 NIOSH Method 1500

Domain 2: Representative
Metric 2: Geographic Scope
High
X
1
1
US
Metric 3: Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4: Temporal Representativeness
Medium
X
2
4
Data older than 10 years (2003) but after PEL
Metric 5: Sample Size
Medium
X
1
2
Only given a range
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Medium
X
1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Medium
X
1
2
None discussed, but NIOSH method addresses variability/

uncertainty in the method
Overall Quality Determination^
High

1.6

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
NIOSH Method P&CAM 127
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
X
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
None discussed, but NIOSH method addresses variability/

uncertainty in the method
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
141
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Source Citation: Gilles, D.,Anania, T. L.,Ilka, R.. 1977. Health hazard evaluation report no. HHE 77-12-418, Airtex Products, Fairfield,
Illinois.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970629
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Sampling Location:
Exposure Duration:
Engineering Control & percent Exposure Reduction:
Use
liquid, vapor
inhalation, dermal
.44ppm
1
1
Area beside degreaser
Area
Area beside degreaser
Full shift
Local exhaust ventilation, vent hoods
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1977) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2 Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed
Overall Quality Determination^
High
1.6
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— continued from previous page
Source Citation: Gilles, D.,Anania, T. L.,Ilka, R.. 1977. Health hazard evaluation report no. HHE 77-12-418, Airtex Products, Fairfield,
Illinois.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970629
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
143
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Source Citation: Johnson, P.. 1980. Health hazard evaluation report no. HHE 80-48-689, Miami Carey Inc., Monroe, Ohio.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970628
EXTRACTION
Parameter Data
Life Cycle Stage: Use
Exposure Concentration (Unit): 4.0-11.9 mg/m3
Worker Activity: Hanging products to be dip painted.
Type of Sampling: Personal, area
Exposure Duration: 2 hours
Exposure Frequency: 6-8 hours/40 hour week
Engineering Control & percent Exposure Reduction: Slot exhaust hood
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 No method given, but HHE done by NIOSH.
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope High x 1 1
Applicability High x 2 2
Temporal Representativeness Medium x 2 4
Sample Size Medium x 1 2
US
Workplace that utilizes TCE
Data older than 10 years (1980) but after PEL
range given but no other statistics
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Unacceptable x 1
4
No metadata given
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low x 1
3
Not addressed
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 1.9.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
144
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Source Citation:
Type of Data Source
Hero ID
Kominsky, J. R.. 1976. Health hazard evaluation report no. HHE 76-24-350, Dana Corporation, Tipon, Indiana.
Occupational Exposure; Monitoring Data;
3970625
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Engineering Control & percent Exposure Reduction:
Use
liquid, vapor
inhalation, dermal
7 - 797 ppm
20
1
Degreaser Operator
157; 12 indirectly and 8 directly affected.
Personal
Local Exhaust ventilation
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
145
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Source Citation: Fannick, N.. 1979. Health hazard evaluation report no. HHE 79-18-627, Standard Folding Cartons, Inc., Jackson Heights,
New York.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970623
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Use
liquid, vapor
inhalation, dermal
1.0 - 1.6
4
1
Gluing cardboard boxes
Area
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
High

1.6

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 No method given, but HHE done by NIOSH.
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High x 1 1 US
High X 2 2 Workplace that utilizes TCE
Medium X 2 4 Data older than 10 years (1974) but after PEL
Medium X 1 2 range given but no other statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low x 1
3 Only sample type given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed
Overall Quality Determination^
Medium
1.8
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Bloom, T. F.,Kramkowski, R. S.,Cromer, J. W.. 1974. Health hazard evaluation report no. HHE 73-151-141, Essex Wire
Corporation, Kenton, Ohio.
Occupational Exposure; Monitoring Data;
3970621
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
148
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Source Citation: Hervin, R. L.,Reifschneider, R.. 1973. Health hazard evaluation report no. HHE 72-42-76, Steel Tool and Engineering
Company, Taylor Michigan.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970620
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Use
liquid, vapor
inhalation, dermal
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Engineering Control & percent Exposure Reduction:
Em ratio given. No concentration provided.
18
1
Degreasing, Acryloid gluing
Some Local Exhaust Ventilation
EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
High
High
Medium
Low
X 1
x 2
x 2
x 1
1
2
4
3
US
Workplace that utilizes TCE
Data older than 10 years (1972) but after PEL
All discussed with respect to equivalent exposure
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
No metadata since no sampling details were given.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.0.
Continued on next page
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— continued from previous page
Source Citation: Hervin, R. L.,Reifschneider, R.. 1973. Health hazard evaluation report no. HHE 72-42-76, Steel Tool and Engineering
Company, Taylor Michigan.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970620
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
150
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Okawa, M. T.. 1975. Health hazard evaluation report no. HHE 74-96-173, Richdel Corporation, Carson City, Nevada.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970619
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Type of Sampling:
Engineering Control & percent Exposure Reduction:
Use
liquid, vapor
inhalation, dermal
1.7 - 2.9 ppm
3
1
Degreasing
Personal
Some Local Exhaust Ventilation
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 6:
Metadata Completeness
Low
x 1
3
Only sample type given
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

1.7

Worker Activity:

Degreasing

Type of Sampling:

Personal, Area

Analytic Method:

NIOSH method P &CAM 127
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH method P &CAM 127
Domain 2: Representative

1.4

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page

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Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Ruhe, R. L.,Watanabe, A.,Stein, G.. 1981. Health hazard evaluation report no. HHE 80-49-808, Superior Tube Company,
Collegeville, Pennsylvania.
Occupational Exposure; Monitoring Data;
3970617
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
153
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Source Citation: Baumann, A.,Page, E.,Mueller, C.,Burr, G.,Hitchcok, E.. 2008. Health hazard evaluation report no. HETA 2004-0372-3054,
Evaluation of neurological dysfunction among workers exposed to trichloroethylene, Entek International, Lebanon, Oregon.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970616
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Analytic Method:
Use
liquid, vapor
inhalation, dermal
2.0 - 130.0 ppm
517
Short term, 8 hour TWA
Varied
142
Personal, Area
multiple
12 hour work day
3.5 d/w
NMAM Method 1022
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NMAM Method 1022 completed by NIOSH
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
2004, 14 years old (after PEL)
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
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Source Citation:
Type of Data Source
Hero ID
Baumann, A.,Page, E.,Mueller, C.,Burr, G.,Hitchcok, E.. 2008. Health hazard evaluation report no. HETA 2004-0372-3054,
Evaluation of neurological dysfunction among workers exposed to trichloroethylene, Entek International, Lebanon, Oregon.
Occupational Exposure; Monitoring Data;
3970616
EVALUATION
Domain
Metric Rating MWF* Score Comments
Metric 7: Metadata Completeness Medium X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^ High 1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH Method No. P&CAM 127
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation:
Type of Data Source
Hero ID
Ruhe, R. L.. 1982. Health hazard evaluation report
Occupational Exposure; Monitoring Data;
3970595
no. HETA 82-040-119, Synthes Ltd. (USA), Monument, Colorado.
EVALUATION
Domain
Metric
Rating
MWF* Score Comments

Metric 7; Metadata Completeness
Medium
X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
No method given, but HHE done by NIOSH.
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Continued on next page
158
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Source Citation: Burton, N. C.,Monesterskey, J.. 1996. Health hazard evaluation report no. HETA 96-0135-2612, Eagle Knitting Mills, Inc.,
Shawano, Wisconsin.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970594
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
X 1 3 Not addressed

Overall Quality Determination^
High
1.6

1.6

Continued on next page
160
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Source Citation: Rosensteel, R. E.,Lucas, J. B.. 1975. Health hazard evaluation report no. HHE 74-28-212, Westinghouse Air Brake Company,
Wilmerding, Pennsyvlania.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970582
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
161
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Source Citation: Barsan, M. E.. 1991. Health hazard evaluation report no. HETA 90-344-2159, A.W. Cash Valve Manufacturing Corporation,
Decatur, Illinois.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970554
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Use
liquid, vapor
inhalation, dermal
Personal: 4.5-5.2 ppmArea: 1.1-5.3 ppm
8
1
TWA
Open top degreaser
Personal, area
Around the degreaser
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 NIOSH method 1022
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1991) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x
1
2
None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High

1.4

Continued on next
page

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Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Barsan, M. E.. 1991. Health hazard evaluation report no. HETA 90-344-2159, A.W. Cash Valve Manufacturing Corporation,
Decatur, Illinois.
Occupational Exposure; Monitoring Data;
3970554
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation:
Type of Data Source
Hero ID
Gorman, R.,Rinsky, R.,Stein, G.,Anderson, K..
Whitney Aircraft, West Palm Beach, Florida.
Occupational Exposure; Monitoring Data;
3970552
1984. Health hazard evaluation report no. HETA 82-075-1545, Pratt
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Engineering Control & percent Exposure Reduction:
Analytic Method:
Use
liquid, vapor
inhalation, dermal, ingestion
TWA - 0.3-22.9 ppmOnly while operating degreaser: N.D. - 233 pp-
mArea: .4 - 22.5 ppm
62
1
8 hour TWA
Degreasing
7200 total, 29 degreaser operators
Personal, area
Around 10 different degreasers
Varies
roll tops to degreasers, high temp safety switches
NIOSH Method No. P&CAM 127
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH Method No. P&CAM 127
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Continued on next page
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Source Citation: Gorman, R.,Rinsky, R.,Stein, G.,Anderson, K.. 1984. Health hazard evaluation report no. HETA 82-075-1545, Pratt &
Whitney Aircraft, West Palm Beach, Florida.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970552
EVALUATION

Domain Metric
Rating
MWF* Score Comments
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
unacceptable. Otherwise, the overall rating is based on the following scale:
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Source Citation: Niosh,. 1992. Health hazard evaluation report no. HETA-90-223-2211, Thomson Consumer Electronics, Marion, Indiana.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3974943
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Use
liquid, vapor
inhalation, dermal
Personal: 0.01 - 11 ppmArea: 0.02 - 50 ppm
11
1
Degreasing
1900
Personal, area
Degreasers 1, 2, 3, and 4
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 NIOSH Method 1003
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1992) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High
1.4

Overall Quality Determination^

High 1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X
1
2
Method described, in peer review journal assumed to use ac-

ceptable methods
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
Greece (OECD country)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1998) but after PEL
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Addressed through sampling multiple shops
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation: Von Grote, J.,J. C. Hurlimann,Scheringer, M.,Hungerbuhler, K.. 2003. Reduction of Occupational Exposure to Perchloroethy-
lene and Trichloroethylene in Metal Degreasing over the Last 30 years: Influence of Technology Innovation and Legislation.
Journal of Exposure Analysis and Environmental Epidemiology.
Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;
Hero ID 3045042
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Type of Measurement or Method:
Worker Activity:
Use
vapor
inhalation
Estimation Model
Modeling degreaser exposure
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Published Journal Article: Journal of Exposure analysis and

Environmental Epidemiology
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Data based on German facilities (OECD country).
Metric 3: Applicability
High
X
2
2
Degreaser exposure modeling
Metric 4: Temporal Representativeness
Medium
X
2
4
2003, 15 years old
Metric 5: Sample Size
N/A

N/A
N/A - modeled exposures
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
Medium
X
1
2
Sources are cited, but does not provide details on how reported

values were derived from cited sources.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Medium
X
1
2
Variability in parameter values discussed, but no discussion of

uncertainties.
Overall Quality Determination^
High

1.6

Personal

Sampling Location:

Spotting Station

Engineering Control & percent Exposure Reduction:
Kitchen exhaust hood, makeup air unit
PPE:

None

EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH Method 1003
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Data older than 10 years (1997) but after PEL
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness Medium X 1 2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
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Source Citation: Niosh,. 1997. Control of health and safety hazards in commercial drycleaners: chemical exposures, fire hazards, and ergonomic
risk factors.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3044963
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
NIOSH NMAM Method 1022 [NIOSH 2006],
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
x 2
4
Source dataed 2008, but data from earlier; older than 10 years

but after PEL
Metric 5:
Sample Size
High
x 1
1
Discrete samples given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty
Continued on next page
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Source Citation: Baumann, A.,Page, E.,Mueller, C.,Burr, G.,Hitchcock, E.. 2008. Evaluation of Neurological Dysfunction among Workers
Exposed to Trichloroethylene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2947998
EVALUATION

Domain Metric
Rating
MWF*
Score Comments
Metric 7: Metadata Completeness
Medium
X 1
2 None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High

1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
unacceptable. Otherwise, the overall rating is based on the following scale:
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Source Citation: Wadden, R. A.,Hawkins, J. L.,Scheff, P. A.,Franke, J. E.. 1991. Characterization of Emission Factors Related to Source
Activity for Trichloroethylene Degreasing and Chrome Plating Processes. American Industrial Hygiene Association Journal.
Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;
Hero ID 2800647
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Type of Measurement or Method:
Worker Activity:
Use
vapor
inhalation
Estimation Model
Modeling degreaser exposure
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Journal of Exposure analysis and Environmental Epidemiology
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Low
N/A
XXX
1
2
2
1
2
6
N/A
Location of plants not indicated, but US-based study
Degreaser exposure modeling
1991, 27 years old
N/A - modeled exposures
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Transparent and well presented. Well documented.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
X
1
2
Variability in machine types, but no discussion of uncertainties.
Overall Quality Determination^
High

1.6

Metric 2:
Geographic Scope
Medium
x 1
2
EU (OECD)
Metric 3:
Applicability
Unacceptable
x 2
8
Data taken inside test chamber, not expected to be represen-

tative of occupational exposures
Metric 4:
Temporal Representativeness
High
x 2
2
2015, 3 years old
Metric 5:
Sample Size
Medium
x 1
2
Range, mean, and STD given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Only sample type given
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.4.

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Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Kowalska, J.,SzewczyAska, M.,PoAniak, M.. 2014. Measurements of chlorinated volatile organic compounds emitted from
office printers and photocopiers. Environmental Science and Pollution Research.
Occupational Exposure; Monitoring Data;
2534318
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
177
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Source Citation: Fleming, D. A.,Woskie, S. R.,Jones, J. H.,Silver, S. R.,Luo, L.,Bertke, S. J.. 2014. Retrospective Assessment of Exposure to
Chemicals for a Microelectronics and Business Machine Manufacturing Facility. Journal of Occupational and Environmental
Hygiene.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2128566
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Number of Sites:
Worker Activity:
Number of Workers:
Use
liquid, vapor
inhalation
1
Etch and strip resist circuit board
5,028
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Peer-reviewed article, using data not from a frequently used
source
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Low
N/A
X 1
x 2
x 2
1
2
6
N/A
US
Workplace that utilizes TCE
Completed in 2013, but uses data that is over 20 years old.
N/A - qualitative information only
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Sources clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

1.9

High 1.2

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Method described and published Journal Article; therefore,
method assumed to be acceptable
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
High
High
Medium
X 1
x 2
x 2
x 1
3
2
2
2
Iran (non-OECD)
Workplace that utilizes TCE
2011, 7 years old
Mean and STD given but no discrete data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Sample type given, but no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

1.9

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
NIOSH Method 1022
Domain 2: Representative

Metric 6:
Metadata Completeness
Medium
X
1
2
Most metadata given, missing exposure frequency
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
None discussed, but NIOSH method addresses variability/

uncertainty in the method
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Source Citation: Crandall, M. S.,Albrecht, W. N.. 1989. Health Hazard Evaluation Report No. HETA-86-380-1957, York International
Corporation, Madisonville, Kentucky.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2072185
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.4

1.4

Continued on next
page

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Source Citation: Daniels, W. J.,Orris, P.,Kramkowski, R.,Almaguer, D.. 1988. Health Hazard Evaluation Report No. HETA-86-121-1923,
Modern Plating Corporation, Freeport, Illinois.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1877748
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
185
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Source Citation: Dodson, R. E.,Houseman, E. A.,Levy, J. I.,Spengler, J. D.,Shine, J. P.,Bennett, D. H.. 2007. Measured and modeled personal
exposures to and risks from volatile organic compounds. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID 1067092
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Type of Measurement or Method:
Worker Activity:
Environment
gas / vapor
inhalation
Estimation Model
Modeling ambient exposure to VOCs
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Model appears to based on sound approaches and is in peer
reviewed journal, assumed to be of acceptable quality
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Unacceptable
X
2
8
Relates to general ambient exposure to VOCs (not in scope)
Metric 4:
Temporal Representativeness
Medium
X
2
4
2007, 11 years old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Transparent and well presented. Well documented.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Briefly discussed variations in the data.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.1.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation:
Type of Data Source
Hero ID
Teschke, K.,Ahrens, W.,Andersen, A.,Boffetta, P.,Fincham, S.,Finkelstein, M.,Henneberger, P.,Kauppinen, T.,Kogevinas,
M.,Korhonen, K.,Liss, G.,Liukkonnen, T.,Osvoll, P.,Savela, A.,Szadkowska-Stanczyk, I.,Westberg, H.,Widerkiewicz, K.. 1999.
Occupational exposure to chemical and biological agents in the nonproduction departments of pulp, paper, and paper product
mills: an international study. American Industrial Hygiene Association Journal.
Occupational Exposure; Monitoring Data;
1022908
EXTRACTION
Parameter
Data
Life Cycle Stage:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Use
0 - 1006 (no units)
10
4
Short term
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Not described
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US, Canada, and EU
Metric 3:
Applicability
Medium
x 2
4
Use of TCE in workplace not clear
Metric 4:
Temporal Representativeness
Medium
x 2
4
1999, 19 years old
Metric 5:
Sample Size
Medium
x 1
2
Mean, median, and range given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium

2.1

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
187
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Source Citation: Chiang, H. L.,Lin, W. H.,Lai, J. S.,Wang, W. C.. 2010. Inhalation risk assessment of exposure to the selected volatile organic
compounds (VOCs) emitted from the facilities of a steel plant. Journal of Environmental Science and Health, Part A: Toxic/
Hazardous Substances and Environmental Engineering.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 832709
EXTRACTION
Parameter Data
Life Cycle Stage:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Analytic Method:
Use
inhalation
0 - 246 ppb
72
Long-term
Steel Production
Area
Various areas of the steel plant
U.S. EPA Method TO-14
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 Method described and stated to be certified by EPA Method
TO-14
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low X 1 3 Taiwan (non-OECD)
Medium x 2 4 Use of TCE in workplace not clear
High x 2 2 2010, 8 years old
Medium X 1 2 mean and 10th, 50th, and 90th percentile given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2 Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed
Overall Quality Determination^
Medium
1.9
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— continued from previous page
Source Citation: Chiang, H. L.,Lin, W. H.,Lai, J. S.,Wang, W. C.. 2010. Inhalation risk assessment of exposure to the selected volatile organic
compounds (VOCs) emitted from the facilities of a steel plant. Journal of Environmental Science and Health, Part A: Toxic/
Hazardous Substances and Environmental Engineering.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 832709
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
189
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Source Citation: Hsieh, L. L.,Chang, C. C.,Sree, U.,Lo, J. G.. 2006. Determination of volatile organic compounds in indoor air of buildings in
nuclear power plants, Taiwan. Water, Air, and Soil Pollution.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 824990
EXTRACTION

Parameter
Data
Life Cycle Stage:
Use
Physical Form:
gas / vapor
Route of Exposure:
inhalation
Exposure Concentration (Unit):
Average: 212.9 ppb
Number of Sites:
4
Type of Sampling:
Area
EVALUATION

Domain Metric
Rating MWF* Score Comments
Domain 1: Reliability

Metric 1: Methodology
Medium X 1 2 Method described but unclear if it is equivalent to NIOSH/

OSHA
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
Taiwan (non-OECD)
Metric 3:
Applicability
Medium
X
2
4
Use of TCE in workplace not clear
Metric 4:
Temporal Representativeness
Medium
X
2
4
2005, 13 years old (after PEL)
Metric 5:
Sample Size
Medium
X
1
2
Average and STD given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Unacceptable
X
1
4
No metadata given
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.4.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
190
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Source Citation: Xu, X.,Yang, R.,Wu, N.,Zhong, P.,Ke, Y.,Zhou, L.,Yuan, J.,Li, G.,Huang, H.,Wu, B.. 2009. Severe hypersensitivity dermatitis
and liver dysfunction induced by occupational exposure to trichloroethylene. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 730058
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Exposure Duration:
Use
liquid, vapor
inhalation, dermal
18 - 683 mg/m3
60-80
21
TWA
general factory worker - not detailed activity given.
21
Area
5-90 days
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Method described and peer reviewed journal, assumed to use
acceptable method
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
High
High
Medium
X 1
x 2
x 2
x 1
3
2
2
2
China (non-OECD)
Workplace that utilizes TCE
2009, 9 years old
range given but no other statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
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Source Citation: Xu, X.,Yang, R.,Wu, N.,Zhong, P.,Ke, Y.,Zhou, L.,Yuan, J.,Li, G.,Huang, H.,Wu, B.. 2009. Severe hypersensitivity dermatitis
and liver dysfunction induced by occupational exposure to trichloroethylene. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 730058
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

Medium 1.8

N/A
N/A - modeled exposures
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Transparent and well presented. Well documented.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.0.

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page

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
Hein, M. J.,Waters, M. A.,Ruder, A. M.,Stenzel, M. R.,Blair, A.,Stewart, P. A.. 2010. Statistical modeling of occupational
chlorinated solvent exposures for case-control studies using a literature-based database. Annals of Occupational Hygiene.
Occupational Exposure; Published Models for Exposures or Releases;
729521
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Source Citation: Kamijima, M.,Wang, H.,Huang, H.,Li, L.,Shibata, E.,Lin, B.,Sakai, K.,Liu, H.,Tsuchiyama, F.,Chen, J.,Okamura, A.,Huang,
X.,Hisanaga, N.,Huang, Z.,Ito, Y.,Takeuchi, Y.,Nakajima, T.. 2008. Trichloroethylene causes generalized hypersensitivity skin
disorders complicated by hepatitis. Journal of Occupational Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 729431
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Use
liquid, vapor
inhalation, dermal
2.1-2330 mg/m3
4
TWA
Personal, area
on worker and at site where he spends the most of his time.
8-12 h
6 day/week
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X
1
2
Method described and in peer reviewed journal article, as-

sumed to be acceptable
Domain 2: Representative

Metric 2:
Geographic Scope
Low
X
1
3
China (non-OECD)
Metric 3:
Applicability
High
X
2
2
Multiple sites that utilize TCE in the workplace.
Metric 4:
Temporal Representativeness
Medium
X
2
4
source from 2008, but data collected in 2002-2003 (older than

10 years but after PEL)
Metric 5:
Sample Size
Medium
X
1
2
Range, mean, and STD given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Continued on next page
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— continued from previous page
Source Citation: Kamijima, M.,Wang, H.,Huang, H.,Li, L.,Shibata, E.,Lin, B.,Sakai, K.,Liu, H.,Tsuchiyama, F.,Chen, J.,Okamura, A.,Huang,
X.,Hisanaga, N.,Huang, Z.,Ito, Y.,Takeuchi, Y.,Nakajima, T.. 2008. Trichloroethylene causes generalized hypersensitivity skin
disorders complicated by hepatitis. Journal of Occupational Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 729431
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

Medium 2.0

Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Worker Activity:
Number of Workers:
Use
liquid, vapor
inhalation, dermal
Estimated 0-100+ ppm
750
Degreasing
12000

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
X 1
3
Not specified
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
UK study (OECD)
Multiple sites that utilize TCE in the workplace.
Report from 2005, but cites older data (all after PEL)
Some ranges given, but some values with unknown statistics
given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
No metadata given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.3.
Continued on next page
.. 2006. Case-control study on renal cell
. Annals of Occupational Hygiene.
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
Fevotte, J.,Charbotel, B.,Muller-BeautA©, P.,Martin, J. L.,Hours, M.,Bergeret, A.. 2006. Case-control study on renal cell
cancer and occupational exposure to trichloroethylene. Part I: Exposure assessment. Annals of Occupational Hygiene.
Occupational Exposure; Monitoring Data;
729415
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Source Citation: Iavicoli, I.,Marinaccio, A.,Carelli, G.. 2005. Effects of occupationai trichioroethyiene exposure on cytokine ieveis in workers.
Journaf of Occupational and Environmental Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 700401
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Analytic Method:
Use
liquid, vapor
inhalation
Mean of 30.75 - 36.50 mg/m3
24
1
Degreasing
105
Personal
NIOSH Method 1022
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
NIOSH Method 1022
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
Medium
X 1
x 2
x 2
x 1
1
2
4
2
US
Workplace that utilizes TCE
2005, 13 years old (after PEL)
Mean and STD given but no discrete data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
None discussed, but NIOSH method addresses variability/
uncertainty in the method
Overall Quality Determination^
High

1.6

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
Iavicoli, I.,Marinaccio, A.,Carelli, G.. 2005. Effects of occupational trichloroethylene exposure on cytokine levels in workers.
Journal of Occupational and Environmental Medicine.
Occupational Exposure; Monitoring Data;
700401
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation:
Type of Data Source
Hero ID
Bakke, B.,Stewart, P.,Waters, M.. 2007. Uses of and exposure to trichloroethylene in U.S. industry: A systematic literature
review. Journal of Occupational and Environmental Hygiene.
Occupational Exposure; Monitoring Data;
699224
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Use
liquid, vapor
inhalation, dermal
Range of 0 ppm - 637 ppm
1700+
Many
short term, long term
Many
Personal, area
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Data pulled from MEDLINE, TOXLINE, NIOSHTIC, the
NIOSHHealth Hazard Evaluation database and co-written by
NIOSH for the Journal of Occupational and Environmental Hy-
giene
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High x 1 1 US
High X 2 2 Workplace that utilizes TCE
Medium x 2 4 2007, 11 years old (after PEL)
Medium X 1 2 Range, arthimetic mean, geometric mean, and geometric STD
given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x
1 2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1 1
Well addressed.

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page

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— continued from previous page
Source Citation: Bakke, B.,Stewart, P.,Waters, M.. 2007. Uses of and exposure to trichloroethylene in U.S. industry: A systematic literature
review. Journal of Occupational and Environmental Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 699224
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.4

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Uesed Method certified by US EPA Method TO-14
Domain 2: Representative

Metric 2:
Geographic Scope
Low
X 1
3
Taiwan (non-OECD)
Metric 3:
Applicability
Medium
x 2
4
Use of TCE in workplace not clear
Metric 4:
Temporal Representativeness
High
x 2
2
2008, less than 10 years old
Metric 5:
Sample Size
Medium
x 1
2
Average and STD given
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Only sample type given
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Medium
2.0
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Source Citation: Jiun-Horng, T.,Kuo-Hsiung, L.,Chih-Yu, C.,Nina, L.,Sen-Yi, M.,Hung-Lung, C.. 2008. Volatile organic compound constituents
from an integrated iron and steel facility. Journal of Hazardous Materials.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 609426
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
204
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Source Citation: Pantucharoensri, S.,Boontee, P.,Likhitsan, P.,Padungtod, C.,Prasartsansoui, S.. 2004. Generalized eruption accompanied by
hepatitis in two Thai metal cleaners exposed to trichloroethylene. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 707342
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
PPE:
Use
liquid, vapor
inhalation, dermal
3.08 - 40 ppm
11
1
short term
degreasing/cleaning metal
130
Area, Personal
cloth gloves, cloth dust mask
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium x 1 2 Method described, in peer review journal assumed to use ac-
ceptable methods
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
Thailand (non-OECD)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
2004, 14 years old (after PEL)
Metric 5:
Sample Size
High
X
1
1
Discrete samples given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness Low x 1 3 Not addressed
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Source Citation: Pantucharoensri, S.,Boontee, P.,Likhitsan, P.,Padungtod, C.,Prasartsansoui, S.. 2004. Generalized eruption accompanied by
hepatitis in two Thai metal cleaners exposed to trichloroethylene. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 707342
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

Medium 1.9

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
206
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Source Citation: Eriesen, M. C.,Locke, S. J.,Chen, Y. C.,Coble, J. B.,Stewart, P. A.,Ji, B. T.,Bassig, B.,Lu, W.,Xue, S.,Chow, W. H.,Lan,
Q.,Purdue, M. P.,Rothman, N.,Vermeulen, R.. 2015. Historical occupational trichloroethylene air concentrations based on
inspection measurements from shanghai, china. Annals of Occupational Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2799661
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Type of Sampling:
Use
vapor
inhalation
Arithmetic mean broken out across industries:<3 - 770 mg/m3
932
70
short term
area
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Not known (likely method described but could not be verified
for all samples)
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
High
High
Medium
X 1
x 2
x 2
x 1
3
2
2
2
Shanghai, China (non-OECD)
Covers multiple in scope uses
2015, 3 years old
Mean and STD given but no discrete data
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Well addressed.
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
207
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Source Citation: Shipman, A. J.,Whim, B. P.. 1980. Occupational exposure to trichloroethylene in metal cleaning processes and to tetra-
chloroethylene in the drycleaning industry in the UK. Annals of Occupational Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 632849
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Use
vapor
inhalation
0-100 ppm99 percent < 100 ppm97 percent < 50 ppm91 percent < 30
ppm
212
25
time weighted average
Metal Cleaning
personal
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X
1
2
Method described, in peer review journal assumed to use ac-

ceptable methods
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
UK (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data older than 10 years (1980) but after PEL
Metric 5:
Sample Size
Low
X
1
3
Only qualitatively described
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Exposure type and sample type given, no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
Medium

2.0

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— continued from previous page
Source Citation: Shipman, A. J.,Whim, B. P.. 1980. Occupational exposure to trichloroethylene in metal cleaning processes and to tetra-
chloroethylene in the drycleaning industry in the UK. Annals of Occupational Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 632849
EVALUATION
Domain Metric Rating MWF* Score Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
209
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Source Citation: Atsdr,. 2007. Health consultation: Evaluation of indoor air migration in building on-site and adjacent to the Omega Chemical
site: Whittier, Los Angeles County, California: EPA facility ID: CAD042245001.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3978063
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Exposure Frequency:
Analytic Method:
Use
vapor
inhalation
1.7 - 270 ug/m3
60
8
continuous
US EPA Method TO-15 SIM
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
US EPA Method TO-15 SIM
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
High
Unacceptable
X 1
x 2
1
8
US
Ambient and building measurements not related to work sce-
Metric 4:
Metric 5:
Temporal Representativeness
Sample Size
Medium
Medium
x 2
x 1
4
2
2007, 11 years old
Moderately well characterized
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Missing sampling data, type, etc.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
not addressed
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.6.

Continued on next
page

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Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain Metric Rating MWF* Score Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, two of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
Atsdr,. 2007. Health consultation: Evaluation of indoor air migration in building on-site and adjacent to the Omega Chemical
site: Whittier, Los Angeles County, California: EPA facility ID: CAD042245001.
Occupational Exposure; Monitoring Data;
3978063
211
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Source Citation: Fan, A.. 1988. Trichloroethylene: Water contamination and health risk assessment. Reviews of Environmental Contamination
and Toxicology.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 701917
EXTRACTION
Parameter
Data
Life Cycle Stage:
Route of Exposure:
Exposure Concentration (Unit):
Number of Workers:
Use
Inhalation
200-8,000 ppm (article page 57); below 100 ppm (pages 58 and 59)
73 workers exposed to concentrations 14-85 ppm (page 63); 2646 employ-
ees who worked in a manufacturing plant that used TCE as a degreasing
agent (page 70).
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Trusted author i.e., California Dept. of Health Services
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
Low
N/A
X 1
x 2
x 2
1
8
6
N/A
US
Covers exposure to contaminated groundwater
Published 1988 (approx. 30 years old).
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Transparent and well presented. Well documented.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
Not addressed
Overall Quality Determination^
Unacceptable
4 Metric Mean Score: 2.5.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
212
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Source Citation: Dobaradaran, S.,Mahvi, A. H.,Nabizadeh, R.,Mesdaghinia, A.,Naddafi, K.,Yunesian, M.,Rastkari, N.,Nazmara, S.. 2010.
Hazardous Organic Compounds in Groundwater Near Tehran Automobile Industry. Bulletin of Environmental Contamination
and Toxicology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2127942
EXTRACTION

Parameter
Data
Life Cycle Stage:
Environment
Physical Form:
liquid
Route of Exposure:
ingestion
Exposure Concentration (Unit):
97.7-1345.7 ug/L
Number of Samples:
24
Number of Sites:
6
EVALUATION

Domain Metric
Rating MWF* Score Comments
Domain 1: Reliability

Metric 1: Methodology
Medium X 1 2 Method described, in peer review journal assumed to use ac-

ceptable methods
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
Iran (non-OECD)
Metric 3:
Applicability
Unacceptable
X
2
8
Data for groundwater contamination
Metric 4:
Temporal Representativeness
High
X
2
2
2010, 8 years old
Metric 5:
Sample Size
Low
X
1
3
Not well characterized
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
X
1
3
Basic metadata present
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.7.
Continued on next page
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— continued from previous page
Source Citation: Dobaradaran, S.,Mahvi, A. H.,Nabizadeh, R.,Mesdaghinia, A.,Naddafi, K.,Yunesian, M.,Rastkari, N.,Nazmara, S.. 2010.
Hazardous Organic Compounds in Groundwater Near Tehran Automobile Industry. Bulletin of Environmental Contamination
and Toxicology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2127942
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
214
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Source Citation:
Type of Data Source
Hero ID
U.S, E. P. A.. 2014. Degreasing with TCE in commercial facilities: Protecting workers.
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
3045553
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Engineering Control & percent Exposure Reduction:
PPE:
Use
liquid, vapor
inhalation, dermal
Closed-loop vapor degreasers/up to 98 percent emission reduction
Solvent-resistant gloves, long sleeves, coveralls, chemical splash eye pro-
tection, full-face respirators.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Cites frequently used sources
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
X
2
2
2014 report
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Transparent and well presented. Well documented.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not addressed
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
r If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
215
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Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter Data
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EPA peer reviewed draft risk evaluation, assumed to use high

quality data
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Data is for 1-BP; however, has information (worker activities,

process descriptions, etc.) directly applicable to TCE occupa-

tional scenarios
Metric 4:
Temporal Representativeness
High
X
2
2
Report from 2016
Metric 5:
Sample Size
N/A

N/A
N/A - sample data for 1-BP not TCE
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
All data sources clearly documented
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
Detailed uncertainty section
Overall Quality Determination^
High

1.0

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
216
U.S, E. P. A.. 2016. TSCA work plan chemical risk assessment: Peer review draft 1-bromopropane: (n-Propyl bromide) spray
adhesives, dry cleaning, and degreasing uses CASRN: 106-94-5.
Occupational Exposure; Completed Exposure or Risk Assessments;
3355305
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter Data
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1; Reliability

Metric 1;
Methodology
High
X
1
1
Not specified
Domain 2; Representative

Metric 2;
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3;
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4;
Temporal Representativeness
Low
X
2
6
Both pre- and post-PEL data
Metric 5;
Sample Size
Low
X
1
3
mean given, no other statistics
Domain 3; Accessibility/Clarity

Metric 6;
Metadata Completeness
Low
X
1
3
Moderately well documented
Domain 4; Variability and Uncertainty

Metric 7;
Metadata Completeness
Low
X
1
3
No discussion of uncertainty or variability
Overall Quality Determination^
Medium

2.2

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
217
Ruijten, M. W.,Verberk, M. M.,SallA©, H. J.. 1991. Nerve function in workers with long term exposure to trichloroethene.
British Journal of Industrial Medicine.
Occupational Exposure; Monitoring Data;
65298
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Source Citation: European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID 3827429
EXTRACTION
Parameter Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
PPE:
MFC
liquid, vapor
inhalation, dermal
Geometric mean 0.6 (ppm)Max 128 (ppm)98.5 percent sample <10 ppm
837
1
8-hr TWA
Process operators, maintenance, and overall plant employees.
75 staff + up to 60 contractors
PBZ
Everywhere
Wear respiratory protective equipment when doing maintenance on pro-
duction lines.
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Low X 1 3 Specific methods not provided for exposures. Peer-reviewed
by the Scientific Committee on Toxicity, Ecotoxicity, and the
Environment (CSTEE)
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace occupational scenario within scope of risk evalua-
Metric 4:
Temporal Representativeness
Low
X
2
6
Data is from 1991, 27 years old
Metric 5:
Sample Size
Medium
X
1
2
837 data points, well characterized with statistics but no dis-

crete data points beyond max.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Medium X 1 2 Sample type, duration, time period, and other metrics pro-
vided.
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Source Citation:
Type of Data Source
Hero ID
European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Occupational Exposure; Completed Exposure or Risk Assessments;
3827429
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low X 1 3 Not addressed.
Overall Quality Determination^
Medium 2.2

Metric 6: Metadata Completeness
Unacceptable x 1
4 Dataset provides method but does not detail the sample type
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3 Not addressed.
Overall Quality Determination^
Unacceptable
4 Metric Mean Score: 2.6.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
221
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Source Citation:
Type of Data Source
Hero ID
European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Occupational Exposure; Completed Exposure or Risk Assessments;
3827429
EXTRACTION
Parameter
Data
Life Cycle Stage:
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Bulk and Dust Particle Size Distribution:
Engineering Control & percent Exposure Reduction:
PPE:
Metal Cleaning -HSE inspectors
liquid, vapor
inhalation
24 samples <30 ppm.All samples < 50 ppm
25
12
8-hr TWA
degreasing operators
unknown
PBZ
unknown
unknown
unknown
unknown
unknown
unknown
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Specific methods not provided for exposures. Peer-reviewed

by the Scientific Committee on Toxicity, Ecotoxicity, and the

Environment (CSTEE)
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
European Study (OECD)
Metric 3:
Applicability
High
x 2
2
Workplace occupational scenario within scope of risk evalua-
Metric 4:
Temporal Representativeness
Low
x 2
6
Data is from 1984s-1994
Metric 5:
Sample Size
Medium
x 1
2
25 data points, but does not provide a true range of data-just
a percenentage of data points that are under set concentration
metrics.
Continued on next page
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Occupational Exposure; Completed Exposure or Risk Assessments;
3827429
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
X 1
2
Sample type and exposure type provided but other key metrics
are not.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X 1
3
Not addressed.
Overall Quality Determination^
Medium

2.2

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
Specific methods not provided for exposures. Peer-reviewed

by the Scientific Committee on Toxicity, Ecotoxicity, and the

Environment (CSTEE)
Domain 2: Representative

Domain
Metric
Rating MWF*
Score
Comments

Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2
Sample type and exposure type provided but other key metrics
are not.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
Limited discussion about how the range of exposure can be
influenced.
Overall Quality Determination^
Medium
2.1

2.2

1.6

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Source Citation: Halogenated Solvents Industry Alliance, Inc.. 2018. Re: Docket no. EPA-HQ-OPPT-2016-0737. EPA-HQ-OPPT-2016-0737-
0103.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 5176415
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Parameter
Data
Life Cycle Stage: Manufacture
Process Description: No
Total Annual U.S. Volume (and percent of PV): 145,000,000 kg/yr
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
EPA document
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Low
Low
Low
X 1
x 2
x 2
x 1
1
6
6
3
US
1992
Nearly 30+ yrs old
single value, no statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Cites sources for all data used.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No discussion of uncertainty or variability
Overall Quality Determination^
Low

2.3

Parameter
Data
Life Cycle Stage: Import
Process Description: No
Total Annual U.S. Volume (and percent of PV): 19,800,000 kg/yr
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
EPA document
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Low
x 2
6
1985
Metric 4:
Temporal Representativeness
Low
x 2
6
Over 30 yrs old
Metric 5:
Sample Size
Low
x 1
3
single value, no statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
x 1
1
Cites sources for all data used.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of uncertainty or variability
Overall Quality Determination^
Low

2.3

Parameter
Data
Life Cycle Stage: Export
Process Description: No
Total Annual U.S. Volume (and percent of PV): 10,600,000 kg/yr
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
EPA document
Domain 2: Representative

Metric 6:
Metadata Completeness
High
x 1
1
Cites sources for all data used.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of uncertainty or variability
Overall Quality Determination^
Low

2.3

Data

Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Use
Degreasing
No

EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Well cited.
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Medium
Low
N/A
X 1
x 2
x 2
3
4
6
N/A
Unknown
2005
< 15 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Cites sources for all data used.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No discussion of uncertainty or variability
Overall Quality Determination^
Low

2.3

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
ICIS sourced data
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
TCE Producers
Metric 4:
Temporal Representativeness
High
X
2
2
First published in 2000, but updated 2014
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Cites sources for all data used.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of uncertainty or variability
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
235
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Source Citation: Hsia,. 2008. Chlorinated solvents - The key to surface cleaning performance.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3982144
EXTRACTION
Parameter
Data

Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Possible Physical Form:
Use
Degreasing
Yes
Liquid, Vapor

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X 1
1
Halogenated Solvents Industry Alliance document.
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
High
High
High
N/A
X 1
x 2
x 2
1
2
2
N/A
US
Operation that uses TCE
2008 - 10 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Nothing cited/documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
High

1.3

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
IARC/WHO document
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Data ftom World Health Organization, includes both US and

non-US, OECD countries
Metric 3:
Applicability
High
x 2
2
information covers in scope uses
Metric 4:
Temporal Representativeness
Low
x 2
6
Report from 2014, but cites data over 20 years old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
x 1
1
Sources, methods, assumptions clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A
N/A No Comment.
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
237
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Source Citation: 2014. Exposure scenario: Use: Trichloroethylene as an extraction solvent for removal of process oil and formation of the
porous structure in polyethylene based separators used in lead-acid batteries.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3970806
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Number of Sites:
Operating Days per Year and Batches per Day:
Use
Manufacture of polyethylene battery separators
Yes
1
365
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Clear description of operation, procedures, etc.
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
EU
Metric 3:
Applicability
High
x 2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
x 2
2
2014, 4 years old
Metric 5:
Sample Size
High
x 1
1
Reasonably well characterized.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
x 1
2
Basic Metadata present.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
x 1
2
Addressed in a general sense.
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
238
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Vlisco Netherlands, B. V.. 2014. Chemical safety report Part A: Use of trichloroethylene as a solvent for the removal and
recovery of resin from dyed cloth.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3970833
EXTRACTION

Parameter
Data
Life Cycle Stage:
Use
Life Cycle Description (Subcategory of Use):
Resin Extraction from Fabric
Process Description:
Yes
Number of Sites:
1
Possible Physical Form:
Liquid, vapor
Chemical Concentration:
Pure
EVALUATION

Domain Metric
Rating MWF* Score Comments
Domain 1: Reliability

Metric 1: Methodology
High X 1 1 Reliable, trusted source
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
EU
Metric 3:
Applicability
High
X
2
2
Workplace that utilizes TCE
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Well documented
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
High

1.1

N/A
N/a
Overall Quality Determination^
High

1.6

* MWF = Metric Weighting Factor
r If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
241
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Atsdr,. 2014. Draft toxicological profile for trichloroethylene.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3982339
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Possible Physical Form:
Manufacture
Manufacture
Yes
1960: 354,000,000 lbsl970: 612,000,000 lbsl980: 267,000,000 lbsl987:
195,000,000 lbs2005: est. 320,000,000 lbs2011: est. 270,000,000 lbs
All US producers: DOW Chemical in Freeport, TX,PPG Industries,
Lake Charles, LA
Liquid, Vapor
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
US Dept. of Health and Human Services - Agency for Toxic
Substances and Disease Registry
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
High
N/A
X
X
X
1
2
2
1
2
2
N/A
US
Industry that makes TCE
2014, 4 years old.
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Well documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^ High 1.0
* MWF = Metric Weighting Factor
r If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
242
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Jordan, B. ruce C.. 1994. Memorandum: Transmittal of alternative control technology documents.
Type of Data Source
Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID
3860917
EXTRACTION

Parameter
Data
Life Cycle Stage: EPA
Life Cycle Description (Subcategory of Use): Industry Guidance on VOC reduction
Process Description: No
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
EPA
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
Report is on control of emissions to air from industrial wastew-

ater. Releases to air out of scope and fate of TCE after entering

industrial wastewater stream outside perview of engineers
Metric 4:
Temporal Representativeness
Low
x 2
6
1994, 24 years old
Metric 5:
Sample Size
Low
x 1
3
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
Sources cited, but not well described or attributed to data.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.8.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
243
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Chimcomplex, S. A. Borzesti. 2014. Analysis of alternatives: Industrial use of trichloroethylene (TCE) as a solvent as a
degreasing agent in closed systems.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3970830
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Manufacture
Manufacture and use of TCE
Yes
Global Consumption: 429500 tonnes
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
x 1
2
Company that produces TCE
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
N/A
X 1
x 2
x 2
2
2
2
N/A
EU
Industry that makes TCE
2014, 4 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Primary source, but no documentation provided.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
244
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Spin,. 2017. SPIN substances in preparations in nordic countries tetrachloroethylene, Part 2.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3981134
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Manufacture
Manufacture of TCE
No
2014 TCE in preparationsSE: 22 tonnesNO: 17.1 tonnesDK: 1.9 ton-
nesFI: -
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
x 1
3
Methods not specified
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
N/A
X 1
x 2
x 2
2
2
2
N/A
SE, FI, DK, NO (OECD countries)
in scope uses
2014, 4 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
No metadata given
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 1.9.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
245
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Carex, Canada. 2008. Priority environmental carcinogens for surveillance in Canada: Preliminary priority list.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3978370
EXTRACTION
Parameter
Data

Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Use
Variety
No
Canada:
49
710 tonnes

EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Medium
X 1
2
School of Environmental Health, Department of Health Care
& Epidemiology, and Department of Geography, Canada
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
Medium
N/A
X 1
x 2
x 2
2
2
4
N/A
Canada (OECD)
in scope uses
2008, 10 years old
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
Sources documented, but no other metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
Medium

1.9

Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
x 1 2
Peer reviewed article, uses acceptable but not frequently used
sources

Continued on next page
247
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation: Doherty, R. E.. 2000. A history of the production and use of carbon tetrachloride, tetrachloroethylene, trichloroethylene
and 1,1,1-trichloroethane in the United States: Part l"historical background; carbon tetrachloride and tetrachloroethylene.
Environmental Forensics.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 194808
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
us
Metric 3:
Applicability
High
X
2
2
in scope uses
Metric 4:
Temporal Representativeness
Low
X
2
6
Report is from 2000 (less than 20 years old) but most data
cited is older than 20 years
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1 Sources, methods, assumptions clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A No Comment.
Overall Quality Determination^ Medium 1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
248
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2017. Preliminary information on manufacturing, processing, distribution, use, and disposal: Trichloroethylene.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3827394
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Manufacture
TCE Manufacture and Import
2012: 220,536,812 lbs2013: 198,987,532 lbs2014: 191,996,578 lbs2015:
171,929,400 lbs
13
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EPA
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
High
X
2
2
Industry that makes TCE
Metric 4:
Temporal Representativeness
High
X
2
2
2017, 1 year old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Basic Metadata present.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^ High 1.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
249
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: 1989. Alternative control technology document - Halogenated solvent cleaners.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3860356
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Batch Size:
Operating Days per Year and Batches per Day:
Possible Physical Form:
Use
Degreasing
Yes, description of multiple degreasing systems
Varies
Varies
Liquid, vapor
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 EPA
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
us
Metric 3:
Applicability
High
X
2
2
Industry that uses TCE
Metric 4:
Temporal Representativeness
Low
X
2
6
1989, 29 years old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Sources are well cited. Meta data complete.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A N/A No Comment.
Overall Quality Determination^ High 1.6
* MWF = Metric Weighting Factor
r If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
250
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 1980. Waste solvent reclamation.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3840001
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Manufacture
Recovery
Yes, description of multiple recovery processes
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 EPA document
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
us
Metric 3:
Applicability
High
X
2
2
information for solvent recovery
Metric 4:
Temporal Representativeness
Low
X
2
6
1995, 23 years old
Metric 5:
Sample Size
N/A

N/A No Comment.
Overall Quality Determination^ High 1.6
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
251
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Doherty, R. E.. 2000. A history of the production and use of carbon tetrachloride, tetrachloroethylene, trichloroethylene and
1,1,1-trichloroethane in the United States: Part 2 - Trichloroethylene and 1,1,1-trichloroethane. Environmental Forensics.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2923308
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Use
Solvents (for cleaning and degreasing)
approximately 115 million pounds in 1996
2
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Peer reviewed article, uses acceptable but not frequently used
sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Geographic Scope
Applicability
Temporal Representativeness
High
High
Low
X 1
x 2
x 2
1
2
6
US
in scope uses
Report is from 2000 (less than 20 years old) but most data
cited is older than 20 years
Metric 5: Sample Size
N/A
N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Sources, methods, assumptions clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A
N/A No Comment.
Overall Quality Determination^
Medium
1.7

Parameter
Data
Life Cycle Stage: Use
Life Cycle Description (Subcategory of Use): Batch Vapor degreaser
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X
1
2
Northeast Waste Management Officials' Association - uses
high-quality non-standard sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
N/A
XXX
1
2
2
1
2
4
N/A
US
Workplace that utilizes TCE
Data older than fO years but less than 20 years
N/A - only process description information given
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
sources clearly documented
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
No discussion of uncertainty or variability
Overall Quality Determination^
High

1.6

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
EPA
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Unacceptable
x 2
8
List of chemicals subject to emergency planning, no informa-

tion relevant to TCE conditions of use
Metric 4:
Temporal Representativeness
High
x 2
2
2015, 3 years old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
x 1
1
Sources cited and clearly described.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.9.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
254
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Dyer, M.. 2003. Field investigation into the biodegradation of TCE and BTEX at a former metal plating works. Engineering
Geology.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3570965
EXTRACTION
Parameter
Data

Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Number of Sites:
Possible Physical Form:
Groundwater
Groundwater Study
No
1
Liquid

EVALUATION
Domain Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High X 1 1 Journal article

Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Unacceptable x 2
Metric 4: Temporal Representativeness Medium x 2
Metric 5: Sample Size N/A
2 UK
8 Field work looking at biodegradation of TCE in groundwater
near a closed metal plating factory. Outside scope.
4 2003, 15 years old
N/A No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1 Sources cited and clearly described.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A No Comment.
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.3.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
255
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 1977. Control of volatile organic emissions from solvent metal cleaning.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3827321
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Possible Physical Form:
EPA
Guidance to inspectors on VOC reduction
No
Vapor
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 EPA document
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
us
Metric 3:
Applicability
Unacceptable
X
2
8
Old 1977 guidelines on controling VOCs from metal cleaning.
Outdated, no new data
Metric 4:
Temporal Representativeness
Low
X
2
6
1977, 42 years old
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Low X 1 3 Sources cited, but not well described or attributed to data.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A N/A No Comment.
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.7.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Type of Data Source
Facility; Completed Exposure or Risk Assessments;
Hero ID
3827429
EXTRACTION

Parameter
Data
Life Cycle Stage: Manufacture
Process Description: No
Total Annual U.S. Volume (and percent of PV): EU: 51,000,000-225,000,000 kg
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EU Chemicals Bureau peer reviewed risk assessment for TCE
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace scenario within scope of risk evaluation.
Metric 4:
Temporal Representativeness
Low
X
2
6
Most data from <1996
Metric 5:
Sample Size
Medium
X
1
2
Provides a large range of possible values and is uncertain.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Cleary documented sources and reasonably articulated as-

sumptions, but not fully transparent
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Discusses uncertainty in overall production and importation
Overall Quality Determination^ Medium 1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
257
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Source Citation: European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Type of Data Source Facility; Completed Exposure or Risk Assessments;
Hero ID 3827429
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Use
Metal Degreasing
No
EU: 63,140,000kg
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EU Chemicals Bureau peer reviewed risk assessment for TCE
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace scenario within scope of risk evaluation.
Metric 4:
Temporal Representativeness
Low
X
2
6
Most data from <1996
Metric 5:
Sample Size
Medium
X
1
2
Provides annual use across all of the EU
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Cleary documented sources and reasonably articulated as-

sumptions, but not fully transparent
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Discusses uncertainty in amount used in production.
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
258
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Type of Data Source Facility; Completed Exposure or Risk Assessments;
Hero ID 3827429
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Use
Adhesives
No
EU: 6,930,000kg
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EU Chemicals Bureau peer reviewed risk assessment for TCE
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace scenario within scope of risk evaluation.
Metric 4:
Temporal Representativeness
Low
X
2
6
Most data from <1996
Metric 5:
Sample Size
Medium
X
1
2
Provides annual use across all of the EU
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Cleary documented sources and reasonably articulated as-

sumptions, but not fully transparent
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Discusses uncertainty in amount used in production.
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
259
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: European Chemicals Bureau. 2004. European Union risk assessment report: Trichloroethylene. EUR 21057 EN.
Type of Data Source Facility; Completed Exposure or Risk Assessments;
Hero ID 3827429
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Use
Intermediate
No
EU: 45,000,000 kg
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
EU Chemicals Bureau peer reviewed risk assessment for TCE
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
European Study (OECD)
Metric 3:
Applicability
High
X
2
2
Workplace scenario within scope of risk evaluation.
Metric 4:
Temporal Representativeness
Low
X
2
6
Most data from <1996
Metric 5:
Sample Size
Medium
X
1
2
Provides annual use across all of the EU
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Cleary documented sources and reasonably articulated as-

sumptions, but not fully transparent
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Medium
X
1
2
Discusses uncertainty in amount used in production.
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
260
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Source Citation:
Snedecor, G.,Hickman, J.
C.,Mertens, J. A.. 2004. Chloroethylenes and chloroethanes.
Type of Data Source
Facility; Reports for Data
or Information Other than Exposure or Release Data;
Hero ID
3859422

EXTRACTION

Parameter

Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Maufacture
Manufacture
Yes
2004:Dow: 59,000 tonsPPG: 91,000 tons
2
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Kirk-Othmer ecyclopedia of chemical technology (frequently

used source)
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
USA
Metric 3:
Applicability
High
X
2
2
Workplace scenario within scope of risk evaluation.
Metric 4:
Temporal Representativeness
Medium
X
2
4
2004 data (>10 but <20 years old)
Metric 5:
Sample Size
High
X
1
1
Discrete data for each US production facility
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
In-text citations for all sources used and fully transparent
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
Not discussed
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
261
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Entek International Limited. 2014. Analysis of alternatives: Use of trichloroethylene as an extraction solvent for removal of
process oil and formation of the porous structure in polyethylene based separators used in lead-acid batteries.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3970832
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Possible Physical Form:
Use
Battery Separators
Yes
10-100 metric tons
1
liquid, vapor
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
x 1
2
Data from site using TCE, assumed to have reliable process
description information
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
High
X 1
x 2
x 2
x 1
2
2
2
1
UK based company
Workplace scenario within scope of risk evaluation.
Data from 2014 (<10 years old)
All data is fully characterized
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Data provided directly from manufacturer on the facility's pro-
cess.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
N/A

N/A
No Comment.
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
262
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Niosh,. 2002. In-depth survey report: Control of perchloroethylene exposure (PCE) in vapor degreasing operations, site #3.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3974920
EXTRACTION
Parameter Data
Life Cycle Stage: Surrogate Use
Life Cycle Description (Subcategory of Use): OTVD
Process Description: Yes
Number of Sites: 1
Batch Size: 255 gallon capacity
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 NIOSH (frequently used source)
Domain 2: Representative
Metric 2:
Geographic Scope
High
X
1
1
USA
Metric 3:
Applicability
High
X
2
2
Process description for directy applicable workplace scenario
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data from 2002 (>10 years) that is expected to be similar to
current degreasing processes.
Metric 5:
Sample Size
Low
X
1
3
single value, no statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 NIOSH assessment that clearly describes assessment methods.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A N/A No Comment.
Overall Quality Determination^ High 1.5
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
263
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Source Citation: U.S, E. P. A.,I. C. F. Consulting. 2004. The U.S. solvent cleaning industry and the transition to non ozone depleting
substances.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3982140
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Use
Solvent cleaning
Yes
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
US EPA (frequently used source)
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
Medium
N/A
X 1
x 2
x 2
1
2
4
N/A
USA
Workplace scenario within scope of risk evaluation.
Data from 2004 (>10 years) that is expected to be similar to
current degreasing processes.
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment clearly documents where data is coming from and
is fully transparent
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A
N/A No Comment.
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
264
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: National Institute for Occupational Safety and Health (NIOSH). 2002. In-depth survey report: control of perchloroethylene
(PCE) in vapor degreasing operations, site #4. EPHB 256-18b.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 5071453
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Number of Sites:
Operating Days per Year and Batches per Day:
Surrogate Use
Vacuum Degreasing
Yes
1
Each batch is 20-30 minuts
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
NIOSH (frequently used source)
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
USA
Metric 3:
Applicability
High
X
2
2
Process description for directy applicable workplace scenario
Metric 4:
Temporal Representativeness
Medium
X
2
4
Data from 2002 (>10 years) that is expected to be similar to

current degreasing processes.
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
NIOSH assessment that clearly describes assessment methods.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 NIOSH assessment that clearly describes assessment methods.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A N/A No Comment.
Overall Quality Determination^ High 1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
266
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Orris, P; Daniels, W. 1981. Health Hazard Evaluation Report 80-201-816: Peterson/Puritan Company. HE 80-201-816.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 5099140
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Process Description:
Total Annual U.S. Volume (and percent of PV):
Number of Sites:
Surrogate Use
Use- packaging commercial aerosols.
Yes
unknown
1
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
NIOSH (frequently used source)
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
USA
Metric 3:
Applicability
High
X
2
2
Process description for directy applicable workplace scenario
Metric 4:
Temporal Representativeness
Low
X
2
6
Data from 1980 (>20 years)
Metric 5:
Sample Size
N/A

N/A
No Comment.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
NIOSH assessment that clearly describes assessment methods.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness N/A
N/A No Comment.
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
267
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