vvEPA
United States
Environmental Protection Agency
OSSSS9
Office of
Research arid Development
National Human Exposure Assessment Survey
(NHEXAS)
Arizona Study
Quality Systems and Implementation Plan
for Human Exposure Assessment
Title: Preparation of Filters and PUF for Field Collection of Metals and
Pesticides in Air
Source: The University of Arizona
Notice: The U.S. Environmental Protection Agency (EPA), through its Office of Research and Development (ORD), partially funded
and collaborated in the research described here. This protocol is part of the Quality Systems Implementation Plan (QSIP)
that was reviewed by the EPA and approved for use in this demonstration/scoping study. Mention of trade names or
commercial products does not constitute endorsement or recommendation by EPA for use.
The University of Arizona
Tucson, Arizona 85721
Cooperative Agreement CR 821560
Standard Operating Procedure
SOP-BCO-L-2.0
U.S. Environmental Protection Agency
Office of Research and Development
Human Exposure & Atmospheric Sciences Division
Human Exposure Research Branch

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SOP #BCO-L-2.0
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July 20, 1995
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Preparation of Filters and PUF for Field Collection of Metals and Pesticides in Air
1.0 Purpose and Applicability
This standard operating procedure (SOP) describes the procedures for precleaning filters
and polyurethane foam (PUF) prior to air sampling with these media. The sampling
media are used for sampling indoor air, outdoor air, and personal air.
2.0 Definitions
PUF: polyether type of polyurethane foam used for collection of vapor phase organics.
3.0 References
3.1	R.G. Lewis and K.E. MacLeod; "A Portable Sampler for Pesticides and Semi-
Volatile Industrial Organic Compounds," Anal. Chem., 54; 310-315 (1982).
3.2	Interim Report by Battelle Memorial Institute, Columbus, Ohio, to U.S. EPA/R.G.
Lewis on Cooperative Agreement CR 822082; "Transport and Migration of
Lawn-Applied Pesticides into the Home: Spatial and Temporal Profile."
4.0 Discussion
This procedure provides cleaning methods to reduce potential background contamination
of air sampling media. A Teflon-coated glass fiber filter (Pallflex T60A20) and PUF
plug are used in tandem for air sampling pesticides; an all Teflon filter (Gelman Teflo;
0.2 um pore size) is used for air sampling for metals. The filters and PUF plugs used for
pesticide sampling are pre-cleaned with acetone as this solvent is used for extraction of
the pesticides from these matrices after air sampling. The filters used for sampling metals
do not require precleaning.
5.0 Responsibilities
5.1	Battelle will be responsible for purchasing the filter and PUF material, and for
cleaning these media.
5.2	Battelle will check for background contamination in the cleaned sample lots of
filters and PUF plugs prior to shipment of the materials to UA. Representative
PUF and filters will be extracted and analyzed per SOPs BCO-L-11.0 and BCO-
L-15.0 to determine pesticide residue levels. Representative filters will be

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digested and analyzed per SOPs BCO-L-3.0 and BCO-L-8.0 to determine metals
residue levels.
5.3 Battelle will ship these materials to UA.
Materials and Reagents
6.1 Materials
6.1.1	Soxhlet extractors (small size, e.g. Kontes 585000-0021; and medium
size e.g. Kontes 585000-0022) consisting of extractor, condenser, and 250
mL round-bottom flask.
6.1.2	Heating mantle.
6.1.3	Variac controller.
6.1.4	Tongs and filter tweezers
6.1.5	PUF plugs; open cell PUF; low density (R45 type) with density = 1.4
¦j
lb/ft (0.022 g/cm ); available pre-cut for air sampling from either
University Research Glassware (Carrboro, NC) or Supelco, Inc; PUF plug
size is 22 mm diameter x 76 mm length.
6.1.6	Teflon-coated glass fiber filters (Pallflex T60A20; 25 mm filters for
personal and fixed site pesticide samples.
6.1.7	Vacuum desiccator (Ladd Research Industries)
6.1.8	Large Kim-Wipes (15" x 15").
6.1.9	Aluminum foil
6.1.10	Muffled wide-mouth glass jars.
6.1.11	Polyethylene Zip-lock bags, 4 mils thick (4"x 4" size and quart size).
6.1.12	Teflon tape (1/2" width).
6.1.13	Teflon filters; Gelman Teflo; 0.2 um pore size, 25 mm for personal
metals samples and 0.2 um pore size, 37 mm for fixed site metals samples

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6.1.14 Graduated cylinders
6.2 Reagents
6.2.1	High Purity dry N2 tank (Battelle storeroom).
6.1.2	Boiling chips (Hengar crystals).
6.1.3	Acetone (high purity).
6.1.4	Hexane (high purity)
Procedure
7.1 Cleaning and Packaging Procedure for Pesticides Filter
7.1.1	Load 50 filters into a small Soxhlet extractor using acetone-rinsed
tweezers or tongs. Make sure that the filters are below the height of the
siphon tube.
7.1.2	Add the condenser. Connect the water lines of the condenser to the house
water supply. Turn on the water and check that there are no leaks.
7.1.3	Add 150 mL of acetone to the 250 mL round-bottom flask and 3-4
boiling chips. Connect the flask to the extractor.
7.1.4	Add the heating mantle and Variac. Slowly turn up the heat with the
Variac until the acetone boils smoothly and distills into the extractor.
Extractor should fill and dump every 15-20 min. Watch one cycle and
verify correct operation.
7.1.5	Extract filters for 14-16 h (overnight).
7.1.6	Turn off Variac and remove heating mantle. Allow extractor to cool
about 15 min.
7.1.7	Turn off water. Remove condenser. Tilt extractor body and dump any
residual solvent into the round-bottom flask
7.1.8	Unload filters from Sohxlet with acetone-rinsed tongs or tweezers onto a
clean, hexane-rinsed square of aluminum foil in a laboratory hood; cover

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immediately with a single layer of Kim-Wipe, and allow to dry
undisturbed for about 10 min.
7.1.9	Place all filters in a pre-cleaned wide-mouth glass jar with Teflon-lined
screw-cap lid, and label jar with lot number of the filter media and date
extracted.
7.1.10	Wrap one layer of Teflon tape over joint between top and bottom parts of
glass jar. Store at room temperature until material is shipped to UA.
7.2. Cleaning and Packaging Procedure for Pesticides PUF Plugs
7.2.1	Load 10 PUF plugs into a medium Sohxlet extractor and wedge them in
against the walls of the extractor so that they are below the siphon tube.
Set up 5 extractors for a batch of 50 PUF plugs.
7.2.2	Continue with set-up, extraction, and cool-down as described above in
Steps 7.1.1-7.1.7, using 250 mL acetone in each 500 mL round-bottom
flask.
7.2.3	Wipe inside of vacuum desiccator with acetone-moistened Kim-Wipe.
7.2.4	Unload PUF plugs from Soxhlet using acetone-rinsed tongs into the
vacuum desiccator (40°C, 20" Hg vacuum, 10 mL/min of high purity dry
N2). Dry the PUF plugs in the desiccator for 1 hr.
7.2.5	Using acetone-rinsed tweezers, place each clean, dry PUF plug in a 4" x
4" polyethylene Zip-lock bag. Place 25 bags in a quart size Zip-lock bag
and label with batch number. Store in a -70°C freezer until material is
shipped to UA.
7.3	Cleaning Procedure for Metals Filters
7.3.1 Filters are used as received from the manufacturer. The lot number is
clearly marked for tracking purposes.
7.4	Calculations
None.

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Quality Control
7.5.1	Laboratory Blanks/Material Checks
7.5.1.1	After cleaning and drying 50 Pallflex filters for pesticides, remove
one filter for analysis prior to shipment to the field. Extract and
analyze per SOPs BCO-L-ll.O and BCO-L-15.0.
7.5.1.2	After cleaning and drying 50 PUF plugs for pesticides, remove
one PUF for analysis prior to shipment to the field. Extract and
analyze per SOPs BCO-L-11.0 and BCO-L-15.0.
7.5.1.3	Pesticide levels must be <0.01 fag/filter and <0.01 (ag/PUF plug
for shipment. If levels are greater than this, then the batch must
be re-extracted and re-analyzed.
7.5.1.4	For every 50 filters for metals, remove one filter for analysis prior
to shipment to the field. Digest and analyze per SOP BCO-L-3.0.
Metals levels must be less than 0.01 |ag/filter. If levels are
greater than this, reanalyze the digestate and analyze two more
filters. If two of the three samples are acceptable, use the batch; if
two of the three are not acceptable, then discard the batch.
7.5.2	Field QC
7.5.2.1 For each batch of 50 PUF plugs (or filters), the following
allocation will be used to assure necessary QA/QC samples.
40 PUF
indoor and outdoor air samples at 20 homes
5 PUF
personal air samples in 5 homes
2 PUF
field duplicates of indoor and outdoor air in 1 home
1 PUF
pre-shipment blank (materials suitability)
1 PUF
field blank
1 PUF
field spike
This allocation provides 10% overall QA and 5% field duplicate
QA (2 out of 40) on fixed site (indoor and outdoor) samples. The
handling of field blank and field spike samples is covered in SOP
UA-F-14.0.

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Records
8.1	The laboratory notebook assigned to NHEXAS for pesticides materials
preparation will contain the record of all relevant information for the pesticide
PUF plugs and filters.
(a)	This record book will contain, for each batch extracted, the batch number, the
date of extraction, the purchase order number for the PUF and the date
received, the lot number for the filter media, and the lot number of the acetone
used for extraction.
(b)	This record book will also contain the pesticide levels in the pre-shipment
blanks.
(c)	This record book will be retained in the laboratory where these operations are
performed and will be transferred to the office of the Battelle co-PI at the
conclusion of the program.
8.2	The laboratory notebook assigned to NHEXAS for metals materials will contain
the record of all relevant information for the filters used.
(a)	This record book will contain, for each batch used, the batch number, the date
of analysis, the lot number, and the lot number of reagents used for digestion.
(b)	This record book will also contain the metals levels in the pre-shipment
blanks.
(c)	This record book will be retained in the laboratory where these operations are
performed and will be transferred to the office of the Battelle co-PI at the
conclusion of the program.

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