FOSETYL-AL (ALIETTE)
Pesticide Registration Standard
(123301)
June 1983
Office of Pesticides and Toxic Substances
Environmental Protection
401 M Street, SW.
Washington, D.C.
Agency
EPA =S40/RS-fl3-nin
v_

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REPORT DOCUMENTATION »• **«>** ho. t
PAGE
PB84-206564
4. TMa .nd SuMRI. fqSETYL-AL (ALIETTE)
Pesticide Registration Standard
Ik Raport Data
Issued 6/H3
c.
1, AutheHt)
USEPA, Office of Pesticide Programs, Registration Division
•. *arformlng Organization Rapt. No.
5¥0//2.J-^-o/0
t. Performing Organization N*m* and Addr»M
U.S. Environmental Protection Agency
401 M Street, S.W. (TS-767)
Washington,-J.C. 20460
IS. Prolact/Taafc/Work Unit N«.
11. Contract (O o» CranHG) No.
<©
IS)
12, Spom-oring CNrpinization Nvmtt and Address
Same as #9
IS. Typa of Wapoft A P»riod Cowtil
14.
IS. SupptamaRtary Note*
IS. Abatract (Limit: 200 words)
This document contains information regarding reregistration of pesticide
products containing the subject active ingredient. The document includes how
to register under a registration standard, regulatory position and rationale,
and summaries of data requirements and data gaps. Also included is a bibliography
containing citations of all studies revived by EPA in arriving at the positions
and conclusions contained in the standard.
17. Oocunxnt Analyt)t a. Oaacriptor*
6. Itfantlfian/OpanCiidad Tarm»
«. COSATI Flald/Croup
It. Availability Stataman*.
-tvL.Lp.U
19. Sacurtty Clams (Thl» Raport)
21, No. of Ca®»*

Is-(I V A V L^.cf'
32

S& Security Ctaaa (Ttila Pa«a)
23. PHca
Saa AN5I-Z39.18)	Sm l«i(tr»ctlen> on *«»araa	OTTIONAl FORM 272 <4-77}
(Formerly NTIS-35)
D»p«rtm«nt of Commarea

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FOSETYL-AL PROJECT SUPPORT TEAM
Fred Betz
George Beusch
Carolyn Gregorio
Henry Jacoby
Rick Johnson
John Jordan
Dennis McLane
Science Integration Staff (HED)
Residue Chemistry Branch (HED)
Toxicology Branch (HED)
Product Manager (RD)
Special' Pesticide Review (RD)
Exposure Assessment Branch (HED)
Ecological Effects Branch (HED)
This registration standard was written by the EPA Office of Pesticide
Programs (EPA/OFP) in cooperation with Rhone Poulenc, Inc. Further
information, is available from the Product Manager, Henry Jacoby, EPA/OP?.
401 M Street, S.W,, Washington, DC 20460, telephone (703) 557-1900.

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REGULATORY POSITION AND RATIONALE
Introduction
This Registration Standard presents the regulatory
position of the Environmental Protection Agency (the
Agency) on registration of manufacturing-use products
(MP) containing the fungicide Fosetyl-Al, aluminum tris
(O-ethyl phosphonate). The Agency's position is based
on a consideration of available data. Registration
requests for products containing Fosetyl-Al will be
evaluated based on this standard.
This standard was developed with the cooperation of Rhone
Poulenc, Incorporated. The topical discussions and
data evaluation records (DER's) were written by Rhone
Poulenc, Incorporated and submitted with each study to
the Agency. The Agency reviewed and evaluated the data
and critiqued and revised the DER's and topical
discussions according to its findings. Although written
by Rhone Poulenc, Incorporated, the DER's and topical
discussion reflect the Agency's position on the subject.
Description of Chemical
Fosetyl-Al is the proposed American National Standards,
Incorporated (ANSI) name for aluminum tris (O-ethyl
phosphonate). The pesticidal uses of Fosetyl-Al are
being developed by Rhone Poulenc, Inc.. It is marketed
under the name Aliette1", The Chemical Abstracts Service
(CAS 5 Registry Number is 39148-24-8. The OPP Internal
Control Number (EPA Shaughnessy Number) is 123301.
Fosetyl-Al is a white odorless powder. The empirical
formula is C6H18AIO9P3. Fosetyl-Al melts with
decomposition at temperatures greater than 200° celsius.
The solubility of Fosetyl-Al in water at 20° celsius
is 120 grams per liter.
The structural formula, is:
O
II
CH3CH2-0-P-0
H
A1
Rhone Poulenc, Inc. is the sole producer of Fosetyl-Al.
It is currently registered in ten foreign countries for
use as a fungicide on fruits, vegetables, and ornamentals.
Registration in the United States is pending for use as
a pineapple seed piece (crowns) dip treatment and as a
foliar spray on ornamentals.

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C'. Regulatory Position
Based on a scientific and technical evaluation of the
available data, the Agency has made the following
determinations;
1.	The risk criteria found in section 162.11(a) of
Title 40 Code of Federal Regulations were exceeded for
Fosetyl-Al by exhibiting an oncogenic effect in rats
fed Fosetyl-Al. However, based on the low level of
exposure (i.e. mixer/loader, applicator, planter, and
dietary) estimated to result from the two uses registerable
under this Standard, a preplant dip for pineapple crowns
and formulation for foliar application to field and
greenhouse grown ornamentals, the Agency has determined
that Fosetyl-Al is not likely to cause unreasonable
adverse effects to either man or the environment.
2.	Tolerances of 0.1 part per million (ppm) for pineapples
and 0.1 ppm for pineapple forage must be established.
3.	There is no need to establish reentry intervals for
Fosetyl-Al.
4.	Manufacturing-use pesticide products containing
Fosetyl-Al as a sole active ingredient may be registered
for sale, distribution, reformulation, and use, subject
tn 4- Vv o f o Y*me a ri/^ r»	i f i Atio cr\cr>i i	tti 4-Vs ¦! e	a a t
w U11 w w a, JiIhD d X iwX1 Li X w X wXI m m O \m£ w JL JL JL. w LI x X X II J. o O C3> XXC»Lci X •
D. Regulatory Rationale
The Agency has determined that it can allow the
registration of Fosetyl-Al after considering the following:
1.	Fosetyl-Al degrades in the environment through the
hydrolysis of the ethyl ester bond with subsequent
degradation of the ethanol into carbon dioxide. The
phosphorous acid metabolite is expected to form
precipitates with aluminum, calcium or iron in the
soil. The half life of Fosetyl-Al under aerobic
' conditions in soil is approximately one and one-half
hours• The intermediate metabolites in grapes, pineapple
and the rat are ethanol and phosphoric acid. The
environmental fate of Fosetyl-Al is sufficiently
understood to conclude that little if any environmental
accumulation of the chemical will result.
2.	Residues of Fosetyl-Al remaining in/on harvested
pineapples grown from treated pineapple seed pieces are
undetectable by a method sensitive to 0,10 ppm. However,
the data developed with	labeled Fosetyl-Al indicate
that residues of Forsetyl-Al or its metabolites could
remain in harvested pineapples at or below the level of
detection.
-2-

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3. No ecological hazards of concern resulting from the
use of Fosetyl-Al on pineapple seed pieces or ornamentals
have been identified in the studies reviewed.
4. Dietary and long term worker exposure to Fosetyl-Al
and its degradates will be very low for pineapple crown
treatment and for ornamental uses.
5. Positive oncogenic effects were observed in the rat ¦
two-year feeding study.. An in-depth animal-by-animal
review has been undertaken by the Agency .and a provisional
oncogenic risk assessment based on the rat feeding
study was carried out. The provisional risks are shown
below:
Exposure
Dietary
Applicator
Mixer/loader
Planters*
Pineapple Use
0.27-2.4 X 10-8
Not applicable
0.50-4.0 X 10-7
0.7-6.0 X 10~6
Ornamental Use
none
0.20-2.0 X 10-8
1.0-9.0 X 10-9
¦ Not applicable
*Risk estimate for planters assumes planters will wear
gloves that are impermeable to Fosetyl-Al.
Because of these low levels of risk, the Agency has
determined that the potential adverse effects associated
with the registrable uses are negligible and do not
constitute an unreasonable adverse effect.
These risk estimates,, low as they are, are nonetheless
likely to be overestimates of any actual risk exposure
since they represent linear risk models at the level of
detection, and uncertainties in other inputs to the
risk model were assumed at conservative levels.
E. Criteria for Registration Under This Standard
To be covered by this Standard, products must contain
Fosetyl-Al as the sole active ingredient, bear required
labeling, and conform to the product composition, acute
toxicity limits, and use pattern requirements listed in
Section F of this document.
F. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Standard
To be covered under this Standard, Manufacturing-use
products must contain Fosetyl-Al as the sole active
-3-

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ingredient. Each with an appropriate certification of
limits.
2.	Acute Toxicity Limits
The Agency will consider registration of technical
grade products and MPs containing Fosetyl-Al for any
acute toxicity category, provided that the labeling of
those products bears appropriate precautionary statements.
3.	Use Patterns
To be registered under this Standard manufacturing-use
products containing Fosetyl-Al may be labeled for
formulation only into end-use products for:
"Terrestrial, non-domestic, food uses on: pineapple
crowns {seed pieces).
"Terrestrial, non-domestic, non-food uses on:
ornamentals (including azalea, boxwood, Japanese
holly, juniper, Monterey pine, Pieris japonica,
Pittosporium, rhododendron, and Schefflera).
"Domestic, outdoor uses on: ornamentals {as
specified above).
"Greenhouse, non-food uses on: ornamentals (as
specified above).
REQUIRED LABELING
All manufacturing-use products containing Fosetyl-Al
must bear appropriate labeling as specified in 40 CFR
162.10. Other portions of the guidance package contain
specific information regarding label requirements.
1. Use Pattern Statements
The ingredient statement for MPs must list the active as:
Aluminum tris (0-ethylphosphonate)				%.
In addition, all MPs must state that they are intended
only for formulation into end-use products for any of
the use patterns listed above. (Specify those sites
listed in Use Patterns ih Section F. 3•) A limiting
factor will be the data that support these use patterns.
2. Precautionary Statements
Labels for all MP products containing Fosetyl-Al must bear
statements reflecting the acute human toxicity of the
compound. Fosetyl is in Toxicity Category I for eye
-4-

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irritation; Category III for oral, dermal and inhalation
routes of exposure; and Category IV for dermal irritation
The required precautionary statements associated with
these Toxicity Categories are specified in 40 CFR §162.10
The following environmental hazard statement must appear
on all manufacturing-use product labels:
Do not discharge into lakes, streams, ponds or
public water unless in accordance with NPDES permit.
For guidance contact your Regional Office of the EPA
Labeling statements to end-use products are not required
to be included in this standard,* however, in order to
reduce the oncogenic risks to pineapple seed piece
planters, the following note to user must appear on the
label for the pineapple use:
Note to User; Gloves impermeable to Fosety1-A1
must be worn during the handling and planting of
pineapple crowns (seed pieces).

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GENERIC
1/
Data Requirement
Composition
TGAI
TGAI
TGAI
158.120 Product Chemistry
Product Identity:
6 1-1 - Identity of Ingredients
61-2 - Statement of Composition
61-3	- Discussion of Formation
of Ingredients
Analysis and Certification of
Product Ingredients
62-1	- Preliminary Analysis	TGAI
62-2 - Certification of Limits TGAI
62-3	- Analytical Methods for	TGAI
Enforcement of Limits
Physical and Chemical Characteristics
63-2	- Color	TGAI
63-3 - Physical State TGAI
6 3-4 - Odor TGAI
63-5 - Melting Point TGAI
63-6 - Boiling Point TGAI
TABLE A
DATA REQUIREMENTS FOR FOSETYL-AL
Does EPA Have Data Must Additional
To Satisfy This Data Be Submitted
Requirement? (Yes, Bibliographic Under FIFRA Section
No or Partially)	Citation	3(c)(2)(B)? 	
Yes	00098326	No
Yes	00098326	No
Yes	00098326	No
Yes	00098326	No
Yes	00098326	No
Yes	00098327	No
Yes	00098325	No
Yes	00098325	No
Yes	00098325	No
Yes	00098325	No
Not applicable^/

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
1/	Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c) (2) (B)?
158.120 Product Chemistry
Product Identity:
6 3-7 - Density, Bulk Density,
or Specific Gravity
(continued)
6 3-8 - Solubility
63-9 - Vapor Pressure
63-10- Dissociation constant
63-11- Octanol/water partition
coefficient
63-12- pH
63-13-	Stability
Other Requirements;
64-1	- Submittal of samples
TGAI
TGAI OR PAI
TGAI OR PAI
TGAI OR PAI
PAI
TGAI
TGAI
TGAI
Yes
Yes
Not applicable-*^
Yes
Yes
Yes
Yes
Yes
00098325
00098325
00098325
00098325
00098325
00098325
No
No
No
No
No
No4/
No
1/ Composition: TGAI = Technical grade of the active ingredient; PAI = Pure active ingredient; Choice = Choice of
several test substances determined on a case-by-case basis.
2/ Data are not needed as Fosetyl-Al is a powder, boiling point is not relevant.
3/ Data are not needed as Fosetyl-Al is a non-volative.
4/ A three-month stability study was provided. The study is adequate to support registration of products for uses
covered by this standard. Any additional uses will require a 12-month stability study.
7

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
_1/	Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
PAIRA and plant
metabolites
158.125	Residue Chemistry
171-4 -	Nature of Residue (Metabolism)
-	Plants	PAIRA
-	Livestock
171-4 -	Residue Analytical Method
-	Plant residues	TGAI and metabolities
-	Animal residues	TGAI and metabolities
171-4 - Storage Stability Data	TEP
171-4 - Magnitude of the Residue-
Residue Studies for Each
Food Use
Crop 1 (Pineapples)
—	Crop field trials	PAI
—	Processed Food/Feed	EP
-- Meat/milk/poultry/eggs TEP/EP
Yes
Not applicable
Yes
Not applicable
Yes
Yes
Not applicable
Not applicable
00103249
00103250
00103250
GS-0260-061
00103250
GS-0260-061
No2/
No2/
No2/
No2/
Composition: TGAI = Technical grade of the active ingredient; PAI = Pure active ingredient; PAIRA = Pure active
ingredient, radiolabelled; TEP = Typical end-use product; EP = End-use product.
Data support use on pineapple, additional crops or change in use pattern will require additional data.
8

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)	
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.130 Environmental Fate
DEGRADATION STUDIES-LAB;
161-1 - Hydrolysis
Photodegradation
161-2 - In water
161-3 - On soil
161-4	- In air
METABOLISM STUDIES-LAB;
162-1	- Aerobic Soil
TGAI or PAIRA	A,B,F,H
TGAI or PAIRA	A,B
TGAI or PAIRA	A,
TGAI or PAIRA	A,
TGAI or PAIRA	A,B,F,H
162-2 - Anaerobic Soil	TGAI or PAIRA
162-3 - Anaerobic Aquatic	TGAI or PAIRA
162-4	- Aerobic Aquatic	TGAI or PAIRA
MOBILITY STUDIES;
163-1	- Leaching and	TGAI or PAIRA
Adsorption/Desorption
Leaching
Adsorption
A,B,F,H
Yes
Yes
Yes
Yes
Yes
No
Not Applicable
Not Applicable
Yes
00098370 or
00098325
00098371
00098371
00098731
00106018
00098372
No
No
No
No
No
No^/
No
No
No
00098375
00106019
9

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TABLE A
GENERIF DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.130 Environmental Fate
(continued)
163-2 - Volatility (Lab)	TEP
163-3	- Volatility (Field)	TEP
DISSIPATION STUDIES-FIELD:
164-1	- Soil	TEP
164-2 - Aquatic (Sediment)	TEP
164-3 - Forestry	TEP
164-4 - Combination and	TEP
Tank Mixes
164-5	- Soil, Long-term	TEP
ACCUMULATION STUDIES:
165-1	- Rotational Crops	PAIRA
(Confined)
165-2 - Rotational Crops	TEP
(field)
165-3 - Irrigated Crops	TEP
A,F
A, F
No
No
No
Not Applicable
Not Applicable
Not Applicable
No
No
No
No
No4/
No4/
No5/
No
No
No
No5/
No5/
No5/
No5/
10

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
Data Requirement
V Use 2/
Composition	Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliographic
No or Partially)	Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)? 	
158.130 Environmental Fate
(continued)
165-4 - In Fish
TGAI or PAIRA A,F
No
No6/
165-5 - In Aquatic Non-Target	TEP
Organisms
Not Applicable
No
- Field exposure study
TEP
A
No
1/ Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active ingredient, radiolabelled; TEP =
Typical end-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, Food Crop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic Outdoor;
I = Indoor.
3/ This requirement is waived based on the short half-life of Fosetyl-Al under aerobic conditions and the known fate
of phosphates under anaerobic conditions. This waiver is for preplant pineapple dip only. Additional uses may
require this study.
4 Not required because the active ingredient is a non-volatile salt.
5/ This requirement is waived based on the short half-life (1 J/2 hours) determined in the aerobic soil metabolism study.
6/ This requirement is waived because the octanol/water partition coefficient is low (ranges from 1.7 X 10"^ to
5.2 X 10-3) and the short half-life.
7/ Field study to determine potential exposure to pineapple planters. Contact the Agency concerning protocol and conduct
of this study
11

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.135 Toxicology
ACUTE TESTING:
8 1-1 - Oral LD50	TGAI
Rat/rabbit^/
81-2 - Dermal LD50	TGAI
81-3 - Inhalation LC50 - Rat	TGAI
81-7	- Acute Delayed	TGAI
Neurotoxicity - Hen
SUBCHRONIC TESTING:
82-1	- 90-Day Feeding -
Rodent, Non-rodent	TGAI
Rat
Dog
82-2 - 21-Day Dermal	TGAI
82-3 - 90-Day Dermal	TGAI
82-4 - 90-Day Inhalation -	TGAI
Rat
82-5 - 90-Day Neurotoxicity-	TGAI
Hen/Mammal.
A,B,F,H
A,B,F,H
A,B,F,H
A,B,F,H
Yes
Yes
Yes
Npt Applicable
Yes^/
Yes
Not Applicable
Not Applicable
Not Applicable
00098330
00098331
00098332
00098336
00098337
00098338
No
No
No
No
No
No
No
No
12

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.135 Toxicology
(continued)
CHRONIC TESTING:
83-1 - Chronic Toxicity -	TGAI
2 species: Rodent (Rat)
A,B.F,H
Yes
00098339
000983525/
No
and Non-rodent (Dog)
00098340
83t2 - Oncogenicity Study -
Rat and
Mouse preferred
TGAI
A,B.F,H
Yes
000983396/
000983525/
00098353
No
83-3 - Teratogenicity -
2 species Rabbit
and Rat
TGAI
A,B.F,H
Yes
00098347
00114091
No
83-4 - Reproduction,
2-generation
TGAI
A,B.F,H
Yes
00098348
No
13

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.135 Toxicology
(continued)
MUTAGENICITY TESTING:
84-2 - Gene Mutation
TGAI
A,B,F,H
Ames test/S. Typhimurium (unactivated & activated)
and Yeast Assay (D7)/S. Cerevisiae.
84-2 - Chromosomal Aberration
TGAI
A,B,F,H
Induct. test/E. Coli.(unactivated & activated)
and DNA Repair/E. Coli.
84-2 - Other Mechanisms of
Mutagenicity
TGAI
A,B,F,H
Micronucleus test/ mouse(oral route)
SPECIAL TESTING
85-1 - General Metabolism	PAI or PAIRA
85-2 - Domestic Animal Safety Choice
Yes
Yes
Yes
A,B,F,H
Not Applicable
Yes
00098343
00098345
00098343
00098345
00098345
00098358
No
No
No
No
No
14

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
Data Requirement
1/ Use 2/
Composition	Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliographic
No or. Partially)	Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.135 Toxicology
(continued)
1/ Composition: PAI = Pure active ingredient; PAIRA = Pure active ingredient, radiolabelled; Choice = Choice of
several test substances determined on a case-by-case basis.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, Food Crop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic Outdoor;
I = Indoor.
3/ The rabbit oral LD50 is used for support as it is the most sensitive species for the oral hazard.
4/ The 90-day feeding study requirements are superseded by the chronic feeding studies listed in 83-1.
5/ Study was conducted with phosphorous acid metabolite.
6/ The review of the rat study demonstrates a positive oncogenic effect at the 8,000 and 30,000-40,000 ppm dose levels.
TJ Any request for additional uses of Fosetyl-Al must be supported by (a) either an application exposure study or estim-
ates of applicator exposure and (b) either a dermal penetration study or estimates of dermal penetration.
15

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.145 Wildlife and
Aquatic Organisms
AVIAN AND MAMMALIAN TESTING
71-1 - Avian Oral LD50
7 1-2 - Avian Dietary LC50
Bobwhite Quail
Mallard Duck
71-3 - Wild Mammal Toxicity
71-4 - Avian Reproduction
71-5	- Simulated and Actual
Field Testing -
Mammals and Birds
AQUATIC ORGANISM TESTING
72-1	- Freshwater Fish LC,
50
Bluegill Sunfish
Rainbow Trout
72-2 - Acute LC^q Freshwater
Invertebrates
Daphnia magna
TGAI
TGAI
TGAI
TGAI
TEP
TGAI
TGAI
A,B,F,H
A,B,F,H
A, B,F,H
A,B,F,H
Yes
Yes
No
No
No
Partial
Partial
00098360
00098362
00098363
00119526
No
No
No3/
No4/
No4/
No
5/
No
5/
16

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.145 Wildlife and
Aquatic Organisms
(continued)
72-3 - Acute LC^q Estuarine	TGAI
and Marine Organisms
Grass Shrimp
72-4 - Fish Early Life	TGAI
Stage and Aquatic
Invertebrate Life-Cycle
72-5 - Fish - Life-Cycle	TGAI
72-6 - Aquatic Organism
7 2-7 - Simulated or Actual
Field Testing -
Aquatic Organisms
TGAI, PAI or
Degradation
Product
TEP
A,B,F,H
Partial
Not Applicable
Not Applicable
Not Applicable
Not Applicable
00098368
Yes
6/
No
No
No
No
17

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
_1/	Use 2/
Does EPA Have Data
To Satisfy This
Requirement? (Yes, Bibliographic
No or Partially)	Citation
Must Additional
Data Be Submitted
Under FIFRA Section
Data Requirement
Pattern
3(c)(2)(B)?
158.145 Wildlife and
Aquatic Organisms
(continued)
1/ Composition: TGAI = Technical grade of the active ingredient; PAI = Pure active ingredient, TEP = Typical end-use
product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, Food Crop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic Outdoor;
I = Indoor.
3/ This requirement is waived since the mammalian toxicity data indicate that the chemical will pose a low potential
risk to wild mammals.
4/ This data requirement is waived for pineapple crown dip and ornamental use based on the short half-life of Fosetyl-Al
under aerobic conditions and the octanol/water coefficient that indicate persistence and accumulation are not
expected. These data may be required for additional uses.
5/ The rainbow trout and Daphnia magna studies have been received, however they have not been reviewed.
6/ This study alone is not sufficient to meet this requirement. However, the uses covered in this standard do not
warrant any additional data.
18

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.150 Plant Protection
121-1 - TARGET AREA
PHYTOTOXICITY
EP
No
No
3/
NONTARGET AREA PHYTOTOXICITY
TIER I
122-1 - Seed Germination/
Seedling *Emergence
122-1 - Vegetative Vigor
122-2	- Aquatic Plant Growth
TIER II3/
123-1	- Seed Germination/
Seedling Emergence
123-1
123-2
124-1
124-2
Vegetative Vigor
Aquatic Plant Growth
TIER III
3/
Terrestrial Field
Aquatic Field
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TEP
TEP
No
No
No
No3/
No3/
No3/
19

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.150 Plant Protection
(continued)
\/ Composition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
EP = End-use product.
£/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, Food Crop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic Outdoor;
I = Indoor.
£/ The requirement for submission of these data is being reserved.
20

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TABLE A
GENERIC DATA REQUIREMENTS FOR FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.155 Nontarget Insect
NONTARGET INSECT TESTING-
POLLINATORS
141-1 - Honeybee acute
contact LD50	TGAI
141-2 - Honeybee - toxicity	TEP
of residues on
foliage
141-3 - Wild bees important in TEP
alfalfa pollination -
toxicity of residues
on foliage
141-4 - Honeybee subacute	(Reserved)
feeding study
141-5 - Field testing for	TEP
pollinators
Not Applicable
Not Applicable
Not Applicable
Not Applicable
No
No
No
No
_1/ Composition: TGAI = Technical grade of the active ingredient; TEP = Typical end-use product.
EP = End-use product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, Food Crop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food; G = Forestry; H = Domestic Outdoor;
I = Indoor.
3/ The requirement for submission of these data is being reserved.
21

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TABLE A
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING FOSETYL-AL
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
Y/	Requirement? (Yes,
No or Partially)
Bi b1i ographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)? 	
158.120 Product Chemistry
Product Identity:
61—1 - Identity of Ingredients	MP
61-2 - Statement of Composition	MP
61-3	- Discussion of Formation	MP
of Ingredients
Analysis and Certification of
Product Ingredients
62-1	- Preliminary Analysis	MP
62-2 - Certification of Limits MP
62-3	- Analytical Methods for	MP
Enforcement of Limits
Physical and Chemical Characteristics
63-2	- Color	MP
63-3 - Physical State	MP
63-4 - Odor	MP
63-7 - Density, bulk density, or	MP
specific gravity
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
00098325
00098325
00098325
00098325
00098325
00098327
00098325
00098325
00098325
00098325
No
No
No
No
No
No
No
No
No
No
22

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TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING FOSETYL-AL
Data Requirement
Composition
Does EPA Have Data
To Satisfy This
1/	Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.120 Product Chemistry
(continued)
63-12- pH
63-14- Oxidizing or
action
63-15- Flammability
63-16- Explodability
63-17- Storage Stability
63-18- Viscosity
63-19-	Miscibility
Other Requirements
64-1	- Submittal of Samples
MP
MP
MP
MP
MP
MP
MP
Choice
Yes
Yes
Yes
Yes
Yes
Not applicable
Not applicable
00098325
00098325
00098328
00098328
00098325
No
No
No
No
No
1/ Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active ingredient, radiolabelled; TEP
Typical end-use product; EP = End-use product; MP = Manufacturing-use product. Choice = Choice of several test
substances determined on a case-by-case basis. Required for all uses.
23

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TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURING-USE PRODUCTS CONTAINING FOSETYL-AL
1/
Data Requirement
Composition
Use 2/
Pattern
Does EPA Have Data
To Satisfy This
Requirement? (Yes,
No or Partially)
Bibliographic
Citation
Must Additional
Data Be Submitted
Under FIFRA Section
3(c)(2)(B)?
158.135 Toxicology
ACUTE TESTING
81-1 - Oral LD50	MP
81-2 - Dermal LD5Q	MP
81-3 - Inhalation LC50	MP
8 1-4 - Primary Eye	MP
Irritation - Rabbit
81-5 - Primary Dermal	MP
Irritation
81-6 - Dermal Sensitization	MP
A,B,F,H
A,B,F,H
A,B,F,H
A,B,F,H
A,B,F,H
A,B,F,H
Yes
Yes
Yes
Yes
Yes
Yes
00098330
00098331
00098332
00098333
00098334
00098335
No
No
No
No
No
No
V Composition: TGAI = Technical grade of the active ingredient; PAIRA = Pure active ingredient, radiolabelled; TEP =
Typical end-use product; EP = End-use product; MP = Manufacturing-use product. Required for all uses.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food; C = Aquatic, FoodCrop;
D = Aquatic, Non-Food; E = Greenhouse, Food Crop; F = Greenhouse, Non-Food Crop; G = Forestry; H = Domestic Outdoor;
I = Indoor.
24

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Registration Standards Case D260: Fosetyl-Al
BIBLIOGRAPHY OF STUDIES CONSIDERED IN SUPPORT OP REGISTRATION UNDER THE STANDARD
All studies in this bibliography are usable only with the permission of their
submitter--Rhone-Poulenc—under the provisions of FIFRA §3(c)(1)(D)(i), for
the ten-year period beginning with the date of first product registration
under this standard.
MRID	CITATION
00098325	Rhone-Poulenc Chemical Company (1981) Product Chemistry:
Fosetyl-Al. Includes method LS 74.783 dated July 7,
1980, method dated May 7, 1981 and undated method RE-
18-81. (Compilation! unpublished study received Apr 5,
1982 under 359-705; CDL:247159-A)
00098326	Bertrand, A. (1981) Fosetyl-Al; Composition•of the Technical
Grade Industrial Product (Analysis of 5 Typical Batches):
Ref: AG/CRLD/An AB/SV 164. Includes method P-286-06-80
and method P.306-03/81. (Unpublished study received
Apr 5, 1982 under 359-705: prepared by Rhone-Poulenc
Agrochimie, France, submitted by Rhone-Poulenc Chemical
Co., Monmouth Junction, N.J.,* CDL:247159-B)
00098327	Rhone-Poulenc Agrochimie (1980) Fosetyl-Al or Ca (0—ethyl
Phosphonate Salts of Aluminium or Calcium) Lodometric
Determination in the Technical compounds and formulations.
Method P-286-06-80 DAted July 17, 1980. (Translation;
unpublished study received Apr 5, 1982 under 359-705;
Submitted by Rhone-Poulenc Chemical Co., Monmouth Junction,
N.J.; CDL:247159-C)
00098328	Rhone-Poulenc Agrochimie (19??) Fosety-l-Al Technical
Stability to Heat, Inflammability Explosivity: AG/RD/DARGOIRE
SRPH JD/NC/177. (Unpublished study received April 5, 1982
under 359-705? submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction, N.J.} CDL:247159-D)
00098330	Pasquet, J.; Mazuret, A.; Maratrat, 7; et al. (1977) LS 74-
783 (Aluminium Ethyl Phosphite,- 32 545 R.p., Aluminium
Salt): Acute toxicity in the Rat and Rabbit: R.P./R.D./C.N.G.
No. 19 143-E. (Translationj unpublished study received
April 5, 1982 under 359-705? prepared by Rhone-Poulenc,
France, submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J.; CDL:247160-B)
00098331	Pasquet, J.? Mazuret, A.? Kali fat, R; et al« (1981) Fosetyl-
Al (32 545 R.P., Aluminium Salt): Acute Percutaneous
Toxicity in the Rabbit: Reference C.R. Vitry/C.N.G. No.
21 162-E. (Translation; unpublished study received April 5,
1982 under 359-705; prepared by Rhone-Poulenc Industries,
France, submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J.; CDL:247160-C)
25

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Fosetyl-Al Bibliography page 2
CITATION
Coombs, D.W.; Clark, G.C. (1977) Acute Inhalation Toxicity
in Rats: Four Hour Exposure to the Dust of LS 74.783
(Technical): RNP 79/77546. (Unpublished study received
April 5, 1982 under 359-705; prepared by Huntingdon Research
Centre, England, submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction, N. J.; CDL:247160-D)
Pasquet, J.; Mazuret, A.,* Maratrat, ?; et al. (1981) Fosetyl-
Al (32 545 R.P., Aluminium Salt): Primary Eye Irritation in
in the Rabbit: Reference C.R. Vitry/C.N.G. No. 21 163-E.
(Translation; unpublished study received April 5, 1982 under
359-705; prepared by Rhone-Poulenc Industries, France,
submitted by Rhone-Poulenc Chemical Co., Monmouth Junction,
N.J.; CDL:247160-E)
Pasquet, J.; Mazuret, A.; Maratrat, ?; et al. (1981) Fosetyl-
Al (32 545 R.P., Aluminium Salt): Primary Skin irritation in
in the Rabbit: Reference C.R. Vitry/C.N.G. No.. 21 164-E.
(Translation; unpublished study received April 5, 1982 under
359-705; prepared by Rhone-Poulenc Industries, France,
submitted by Rhone-Poulenc Chemical Co., Monmouth Junction,
N.J.; CDL:247160-F)
Elliott, P.H.; Seaber, J.A. (1979) Screening Test for Delayed
Contact Hypersensitivity with Fosetyl-Al (LS 74-783) in
the Albino Guinea Pig: 79443D/RNP/168. (Unpublished
study received April 5, 1982 under 359-705; prepared by
Huntingdon Research Centre, England, submitted by
Rhone-Poulenc Chemical Co., Monmouth Junction, N.J.;
CDL:247160-G)
Coquet, B.; Guyot, D. ; Galland, L.; et al. (1977) LS 74783:
3 Month Oral Toxicity Study in the Rat: IFRED R 770359
(Translation; unpublished study received April 5, 1982
under 359-705; prepared by Institut Francais de Recherches
et Essais Biologiques, France, submitted by Rhone-Poulenc
Chemical Co., Monmouth Junction, N.J.; CLD:247161-A)
Coquet, B.; Clair, M. (1977) LS 74783 (Aluminium Ethylphosphite)
3 Month Oral Toxicity Study in the Dog: IFRED R- 712110.
A translation of: LS 74783 (Ethylphosphite D'Aluminium):
Toxicite a Terme (3 mois) Par Voie orale Chez le Chien:
IFREB-R 709235. (Unpublished study received April 5, 1982
under 359-705; prepared by Institut Francais de Recherches
et Essais Biologiques, France, submitted by Rhone-Poulenc
Chemical Co'., Monmouth Junction, N.J.; CLD:247161-B)
Kynoch, S.R.; Lloyd, G.K.; Mallard, J.R.; et al. (1979) The
Effect of Repeated Applications of LS 74783 Technical to
the Skin of Rabbits for Twenty-one Days: RNP/123/79314.
(Unpublished study received April 5, 1982 under 359-705;
prepared by Huntingdon Research Centre, England, submitted
by Rhone-Poulenc Chemical Co., Monmouth, N.J.,* CDL: 247161 -C )
26

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Fosetyl-Al Bibliography page 3
MRID
CITATION
00098339	Spicer, E. J. F.; Trumbull, R.R.; Blanchard, G.L.; et al« (1981)
Chronic Toxicity (2 Year) and Carcinogenicity Study in Rats:
IRDC Study No. 347-016. (Unpublished study received April 5,
1982 under 359-705; prepared by International Research and
Development Corp., submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction, N.J.j CDL:247162-66)
00098340	Spicer,	Phillips, L.M.; Richter, W.R.; et al. (1981)
Two-year Dietary Toxicity Study in Dogs: IRDC Study No.
347-023. (Unpublished study received April 5, 1982 under
359-705? prepared by International Research and Development
Corp., submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J.,- CDL:247167-A)
00098343 ' Bouanchaud, D.H.; Cartier, J.R.; Vessieres, ? (1981) Fosetyl-Al
(32 545 R.P., Aluminum Salt); Supplementary Studies of
Mutagenesis in Microorganisms: C.R. Vitry/C.N.G. No. 21
212. (Unpublished study received April 5, 1982 under 359-705?
prepared by Rhone-Poulenc Industries, France submitted
by Rhone-Poulenc Chemical Co., Monmouth J unction, N.J.;
CDL:247173-B)
00098345	Cordier, A.; Fournier, E.; "Viziere, ? (1981) Fosetyl-Al (32
Sys R.P., Aluminium Salt): Micronucleus Test in the
Mouse by the Oral Route: Reference C.R. Vitry/C.N.G. No
21 186-E. (Translation, unpublished study received April
5, 1982 under 359-705? prepared by Rhone-Poulenc Industries
France, submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J. ; CDL:247173-D)
00098347	Pasquet, J.; Le Bail, R.,; Cegeral, ? (1976) Compound LS
74-783? Oral Teratogenicity Study in the Rabbit: Report
R.P./R.D./C.N.G. No. 18917-F. (Translation, unpublished
study received April 5, 1982 under 359-705; prepared by
Rhone-Poulenc, France, submitted by Rhone-Poulenc Chemical
Co., Monmouth Junction, N.J.? CDL:247174-A)
00098348	Palmer, A.K.; Bottornley, A.M.; Barton, S.Jet al. (1981)
Effect of LS 74-783 on Reproductive Function of Multiple
Generations in the Rat: RNP/89/8Q745. (Unpublished study
received April 5, 1982 under 359-705; prepared by Huntingdon
Research Centre, England, submitted by Rhone-Poulenc
Chemical Co., Monmouth Junction, N.J.; CDL:247174-C)
00098352	Spicer, E.J.F.; Phillips, L.M.? Richter, W.R.; et al. (1981)
Life-time Chronic Toxicity and Carcinogenicity Study in-
Rats: IRDC Study No. 347-022. (Unpublished study received
April 5, 1982 under 359-705; prepared by International Research
and Development Corp., Submitted by Rhone-Poulenc Chemical
Co., Monmouth Junction, N.J.; CDL:247176-82)
27

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Fosetyl-Al Bibliography page 4
MRID	CITATION
00098353	Spicer, E.J.F.j Phillips, L.M.; Richter, W.R.; et al. (1981)
24-month Carcinogenicity Study in Mice: IRDC Study No. 347-021.
(Unpublished study received April 5, 1982 under 359-705;
prepared by International Research and Development Corp.,
submitted by Rhone-Poulenc Chemical Co., Monmouth Junction,
N.J.j CDL:247168-71)
00098358	Caillard, C.G.j Deregnaucourt, J.; Garret, C.; et al. (1980) ¦
Monoethylphosphonic Acid, Aluminium Salt (LS 74 783 = 32
545 R.P. , "Aluminium Salt): Effects in a Number of Pharmaco-
logical Tests: R.P./R.D./C.N.G. No. 20 680-E. (Translation;
unpublished study received April 5, 1982 under 359-705,*
prepared by Rhone-Poulenc, France, submitted by Rhone-Poulenc
Chemical Co., Monmouth Junction, N.J.; CDL:247183-E)
00098360	Roberts, N.L.j Phillips, C.N.K. (1981) The Acute Oral Toxicity
(LD50) of LS 74.783 to the Bobwhite Quail: RHP 189
WL/81148. Final report. (Unpublished study received April 5,
1982 under 359-705; prepared by Huntingdon Research Centre,
England, submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J.; CDL:247184-B)
00098362	Roberts, N.L.; Phillips, C.N.K.; Almond, R.H. (1982) The
Subacute Dietary Toxicity (LC50) of LS 74.783 to the Bobwhite
Quail: RNP 189 WL/81699. .Final report. (Unpublished study
received April 5, 1982 under 359-705; prepared by Huntingdon
Research Centre, England, submitted by Rhone-Poulenc
Chemical Co., Monmouth Junction, N.J.; CDL:247184-D)
00098363	Roberts, N.L.; Phillips, C.N.K.; Almond, R.H. (1981) The
Subacute Dietary Toxicity (LCjq) of LS 74.783 to the
Mallard Duck: RNP 189 WL/81699. Final report. (Unpub-
lished study received April 5, 1982 under 359-705; prepared
by Huntingdon Research Centre, England, submitted by Rhone-
Poulenc Chemical Co., Monmouth Junction, N.J.; CDL:247184-E)
00098368	Rhoderick, J.C.; Spare, W.C.; Hutchinson, C. (1981) The
Acute Toxicity of Aluminum-ethyl-phosphonate to Grass
Shrimp, Palaemonetes pugio: Project No. 381-2. (Unpublished
study received April 5, 1982 under 359-705; prepared by
Biospherics, Inc., submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction, N.J.? CDL:247184-J)
00098370	Buys, M.; Bertrand,; Giraud, J.P. (1981) Fosetyl-al (Aluminium
Tris-O-ethylphosphonate) Hydrolysis Study: Ref, AG/CRLD/An/
AB/MB/JPG/CB/613.81. (Unpublished study received April 5,
1982 under 359-705; prepared by Rhone-Poulenc Agrochemie
S.A., France, submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction, N.J.; CDL:247185-B)
28

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Fosetyl-Al Bibliography page 5
CITATION
Bertrand, A. (1981) Fosetyl-al: UV Absorption Characteristics:
Ref. No. AG/CRLD/An/AB/DB/324/81. (Unpublished study
received April 5, 1982 under 359-705; prepared by Rhone-
Poulenc Agrochimie, France, submitted by Rhone-Poulenc
Chemical Co., Monmouth Junction, N.J.; CDL:247185-C)
Hascoet, M. ; Jamet, P. (1978) Aluminium Ithylphosphite
Degradation in the Soil. (Translation France, Ministere
de 1'Agriculture, Institut National de la Recherche
Agronomique, Laboratoire de Phytopharmacie; unpublished
study, received April 5, 1982 under 359-705; submitted by
Rhone-Poulenc Chemical Co., Monmouth Junction, N.J.,
CDL;247185-D)
Buys, M.; Giraud, J.P. (1981) Fosetyl-al (Aluminum Tris-O-ethyl-
phosphonate) Soil Leaching Studies: Ref. AG/CRLD/An/ AB/MB/JPG/
CB/0 25.82. (Unpublished study received April 5, 1982 under
359-705,- prepared by Rhone-Poulenc Agrochemie, France,
submitted by Rhone-Poulenc Chemical Co., Monmouth Junction,
N.J.; CDL:247185-G)
Brockelsby, ۥ; Catchpole, A.; Crouch, R. (1977) Fungicides: Alu-
minum Ethyl Phosphite (LS 74.783 or Aliette): Studies with the
14C-Labelled Compound in vines: AR/1257. (Unpublished study re-
ceived June 8, 1982 under 359-706; prepared by May 6 Baker Ltd.,
Eng. submitted by Rhone-Poulenc, Inc., Monmouth Junction, N.J.;
CDL:247647-B)
Laurent, M.j Chabassol, Y. (1982) Fosetyl-Al (32 545 R.P. Alumin-
ium Salt): Pineapple Metabolism Study: Report C.R. Vitry/CNG-An
No. 4412-E. (Translation; unpublished study received Jun -8,
1982 under 359-706; submitted by Rhone-Poulenc, Inc. Monmouth
Junction, N.J. ; CDL:247647-C)
Buys, M.j Giraud, J.P. Alix, M.; et al. (1982) Fosetyl-Al (Aluminum
Tris-o-ethylphosphonate) Soil Metabolism Study: Ref. AG/CRLD/
AN/ 262.82. (Unpublished study received April 5, 1982 under
359-705; prepared by Rhone-Poulenc Agrochemie S.A., France,
submitted by Rhone-Poulenc Inc., Monmouth Junction, N.J.;
CDL:247820-A)
Bertrand, A.; Buys, M. (1982) Fosetyl-Al--Soil Sorption Studies:
Ref. • AG/CRLD/AN/163.82. (Unpublished study received July 1*3,
1982 under 359-705,* prepared by Rhone-Poulenc Agrochimie S.A.,
France, submitted by Rhone-Poulenc, Inc., Monmouth Junction,
N.J., CDL:247820-B)
29

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Fosetyl-Al Bibliography page 6
MRID	CITATION
00114091	Palmer, A.K., James, R.W. (1977) Effect"of LS 74-783 on pregnancy
. of the Rats RNP/33/76939. (Unpublished study received April 5,
1982 under 359-705; prepared by Huntingdon Research Centre,
England; submitted by Rhone-Poulenc Chemical Co., Monmouth
Junction, N.J.; CDLS'247174-B)
00119526	Biospherics, Inc. (1982) The Acute Toxicity of Fosetyl-Al
to the Bluegill Sunfish (Lepomis macrochirus): Project
No. 82-E-380-B. (Unpublished study received Oct. 28, 1982
under 359-705; submitted by Rhone-Poulenc Chemical Co.,
Monmouth Junction,	CDL:248674-A)
GS-0260-61 Rhone Poulenc, Incorporated (19??) Residue Data in or on Pineapple
Resulting From Aliette Dip and/or Foliar Treatments.
(Unpublished study received May 31, 1982 under Pesticide
Petition 2FG2702.) Prepared and submitted by Rhone-Poulenc,
Incorporated, Monmouth Junction, N.J.; CDL:071591 S 01592.
30

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