OPPT Accomplishments Report
January 2007 - 2009
EPA's Office of Pollution Prevention and Toxics (OPPT) works to ensure that chemicals
manufactured, imported or used in the United States do not pose unreasonable risks to
health or the environment. It also strives to promote the prevention of pollution before it
occurs and to improve environmental stewardship practices in business and government
operations. This report describes OPPT's progress in accomplishing these goals, which are
key components of EPA's overall Strategic Plan (http://www.epa.gov/cfo/plan/plan.htm).
Indeed, every accomplishment is a part of a larger effort to meet one of the Agency's
specific strategic objectives.
Introduction—Read how OPPT's mission and legislative authorities provide a
framework for success.
, ^
Zi
1
Reviewing New Chemicals—Learn about the New Chemicals Program, one of the
Agency's premier risk assessment and management programs. Find out about new
biotechnology products, new chemical nanoscale materials, international efforts,
and more.
Managing Existing Chemicals—Investigate how the Existing Chemicals Program
regulates chemicals in commerce. Find out more about inventory update reporting,
chemicals work on nanoscale materials, global chemical safety, the Security and
Prosperity Partnership of North America, and the recently announced ChAMP.
Reducing Risks from Specific Existing Chemicals—See how OPPT protects
against specific priority chemicals—lead, asbestos, polychlorinated biphenyls
(PCBs), and mercury. OPPT develops regulations and policies designed to reduce
risks to human health and the environment from these specific chemicals.
PHP
ii
Working to Prevent Pollution—Read how OPPT's innovative, environmental
stewardship programs encourage pollution prevention as both a critical
environmental strategy and a sustainable business practice. The programs include
Green Suppliers Network, Design for the Environment, and Green Chemistry, to
name a few.
¦ Cross-Cutting Programs—Use tools and models developed by OPPT to support
and enhance multiple program areas. OPPT's cross-cutting accomplishments
encompass a range of activities—assisting with IT support, program assessment,
community-based partnerships, and risk assessment tools.
Note: As of the publication of this report, external links are current and accurate, and are
offered by way of example only for reference purposes. The EPA is not responsible for
content of non-EPA links.
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Introduction—What We Do
Chemicals are in
just about
everything we use.
Every day we are
surrounded by
chemicals—in fact,
the way we live
would be impossible
OPPT's work contributes to two of the
five major goals outlined by EPA in its
2006 - 2011 Strategic Plan
• By 2011, prevent and reduce
chemical risks to humans,
communities, and ecosystems. (Goal
4; Objective 1; Sub-objective 1)
(http://www.epa.gov/cfo/plan/plan.htm):
without them. Yet, some chemicals can be
potentially dangerous to our health and the
environment. It's the job of EPA's Office of Pollution
Prevention and Toxics (OPPT) to ensure that
commercial and industrial chemicals manufactured,
imported, or used in the United States do not pose
any unreasonable risks to human health or the
environment. And promoting the prevention of
• By 2011, reduce pollution, conserve
natural resources, and improve other
environmental stewardship practices
while reducing costs through
implementation of EPA's pollution
prevention programs. (Goal 5;
Objective 2; Sub-objective 1)	
pollution before it occurs is central to OPPT's work.
Legislative Authorities
Tens of thousands of chemicals are manufactured, imported, or used in the United States
annually. Many new chemicals are being developed each year, and emerging technologies,
such as nanotechnology and biotechnology, are changing the types of materials used in
commerce and in the environment. Under the Toxic Substances Control Act (TSCA) of 1976,
OPPT establishes reporting, record-keeping, testing, and control-related requirements for
new and existing chemicals. Read about OPPT work under TSCA to protect against risks
from new, existing, and specific chemicals.
Under the Pollution Prevention Act (PPA) of 1990, the office works to reduce pollution before
it occurs through innovative changes in production, operation, and use of raw materials.
Read about OPPT's pollution prevention programs' accomplishments.
Two Different Roles
One of the office's major roles is to serve as a gatekeeper/guardian, using its traditional
"command and control" regulatory authorities to keep potentially risky new chemicals out of
the market while assessing and managing the potential risks of existing chemicals. The
organization's other key role is to promote environmental stewardship and sustainability.
OPPT does this through collaborative programs with stakeholders and educational initiatives.
Working to eliminate sources of pollution, OPPT creates tools and makes information
available to better enable industry and the public to make wise chemical choices. See the
new, existing and specific chemicals sections of this report as well as the pollution
prevention and cross-cutting programs sections for how OPPT uses the two roles to promote
chemical safety nationally and internationally.
Report Highlights
From January 2007 through January 2009, OPPT:
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•	Initiated the Nanoscale Materials Stewardship Program (NMSP) in January 2008 to
encourage submission and development of data to help provide a firmer scientific
foundation for regulatory decisions. As of December 2008, 29 companies and
associations submitted information covering 123 nanoscale materials. Seven
companies committed to the basic program and four committed to participate in the
in-depth program to develop data. On January 12, 2009, EPA released its interim
report on the status of the NMSP and possible next steps
(http://www.epa.gov/oppt/nano/nmsp-interim-report-final.pdf).
•	Required new protections that will help protect children from lead poisoning
(http://www.epa.gov/lead/index.html) during renovations and remodeling. OPPT
issued a final rule in March 2008 that requires persons renovating or remodeling pre-
1978 housing or child-occupied facilities to be certified to use practices that ensure
against exposure to lead in paint. On August 21, 2008, EPA issued a proposed rule to
modify and lower the existing fees and establish new fees for various EPA
certifications (http://www.epa.gov/fedrgstr/EPA-TOX/2008/August/
Day-21/tl9432.htm). In December 2008, EPA formed a partnership with the
Coalition to End Childhood Lead Poisoning and HUD to conduct a public service Ad
Council advertising campaign to raise awareness of childhood lead poisoning,
including renovation hazards.
•	Created the Chemical Assessment and
Management Program, or "ChAMP," to implement
the U.S. commitment to assess and initiate action,
where appropriate, on 6,750 high- and moderate-
production volume chemicals by 2012. As of
December 2008, EPA had developed and posted
risk-based prioritizations for 151 HPV chemicals
and had posted hazard-based prioritizations for 55
chemicals. After an extensive stakeholder
engagement process and careful consideration,
EPA announced in September that it will proceed
with two enhancements to ChAMPEH1
(http://www.epa.g0v/champ/pubs/pr0grams.htm#enhancements) including
developing an HPV Challenge-type program for "inorganic" HPV chemicals and
resetting the TSCA Inventory to reflect the chemicals actually in commerce. EPA held
a public meeting on December 8, 2008, to further engage stakeholders in this effort.
•	Responded to three TSCA Section 21 petitions in 2007 and 2008, including a petition
on formaldehyde in pressed wood products. As part of the Agency's efforts to gain a
greater scientific understanding of the potential health risks of formaldehyde's use in
pressed wood products, OPPT issued an Advance Notice of Proposed Rulemaking
(ANPR) on November 25, 2008, that outlines EPA's steps to investigate potential
actions to protect against risks posed by formaldehyde emitted from pressed wood
products used in manufactured homes and other places. OPPT is seeking public input
on these issues and is holding a series of public meetings in early 2009.
•	Reached a milestone in the PFOA Stewardship Program (http://www.epa.gov/oppt/
pfoa/pubs/stewardship/index.html) with member companies' first annual progress
reports received and made publicly available in October 2007 (http://www.epa.gov/
oppt/pfoa/pubs/stewardship/preports.html). In December 2008, OPPT released
1 [23EPA no longer updates this information but it may be useful as a reference or a resource.
The Chemical Assessment and
Management Program (ChAMP)
has been superseded by the
comprehensive approach to
enhancing the Agency's current
chemicals management program
announced by Administrator Lisa
Jackson on September 29, 2009
(http://www.epa.gov/oppt/existing
chemicals).	
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summary tables of 2008 progress reports (http://www.epa.gov/opptintr/pfoa/pubs/
stewardship/preports2.html#summary).
•	Coordinated, for the past two years, the cross-Agency Community Action for a
Renewed Environment (CARE) Program which helps communities develop broad-
based local partnerships to prioritize and address multiple sources of toxic pollutants
in their environment through competitive grants and technical assistance. CARE
works with communities to assess and set priorities for risk-reduction activities and
helps to promote self-sustaining, community-based partnerships to bring solutions to
local risks. Since its first round of cooperative agreement awards in 2005, CARE
grants have reached 64 communities in over 32 states and tribes, totaling $10.4
million. In 2009, about $3 million will be available for additional grants.
•	Provided, through the Electronic Products Environmental Assessment Tool (EPEAT), a
set of environmental performance criteria for computers and monitors and a Web-
based system that enables manufacturers to accurately declare that their product(s)
meet specific environmental criteria. As of January 2009, there were 30
manufacturers with 1053 EPEAT-registered products listed in the EPEAT Product
Registry Web page (http://www.epeat.net/Search.aspx).
•	Established the Safer Detergents Stewardship Initiative (SDSI), a Design for the
Environment (DfE) program to recognize environmental leaders who voluntarily
commit to use of safer surfactants in their products. EPA held the SDSI Recognition
Ceremony on November 19, 2008, and recognized 40 Champions and 21 Partners.
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Reviewing New Chemicals
Under the Toxic Substances
Control Act (TSCA), EPA uses its
traditional regulatory authorities
to control or keep potentially
hazardous new chemicals out of
the market. EPA's New
Chemicals Program (NCP)
(http://www.epa.gov/oppt/
newchems/index.htm) is one of
the Agency's premier risk management programs, and serves a
key gatekeeper function.
One of the targets in "Goal
Four" in EPA's Strategic
Plan is to ensure that new
chemicals introduced into
commerce do not pose
unreasonable risks to
workers, consumers, or the
environment. The plan
foresees this target being
met by 2011.
Specifically, under TSCA Section 5, EPA must be given notice before a new chemical
substance can be manufactured or imported into the United States. This pre-manufacture
notice (PMN) must be submitted at least 90 days prior to the manufacture or import of the
chemical.
The New Chemicals Program reviews submissions to determine if any of the chemicals
warrant prohibiting or limiting their manufacture, processing, or use. Because many PMNs
include little or no toxicity or fate data, the program uses several risk screening approaches
to facilitate assessment in the absence of specific data. This enables rapid evaluation of
potential risks and making risk-management decisions for the new chemicals within the 90-
day timeframe prescribed by TSCA.
More information on the New Chemicals Program: http://www.epa.gov/oppt/newchems/.
Accomplishments
•	A total of 1,724 valid Section 5 notices were received from January 2007 through
June 2008. The majority of the submissions were pre-manufacture notifications
(PMNs) with 1,071 received during this time period. The next largest group was low-
volume exemptions with 630 received during this time period. The remaining notices
were Low Release and Exposure (LoREX) Exemption (http://www.epa.gov/oppt/
newchems/pubs/lorexemp.htm) notices and Test Marketing Exemption (TME)
(http://www.epa.gov/oppt/newchems/pubs/tmexempt.htm) notices.
•	The NCP's P2 Recognition Project recognizes, through an annual award, innovative
new chemical submissions that are inherently safer than those currently in use and
that reduce sources of pollution. The program is especially interested in promoting
chemistries that substitute for existing chemicals that pose greater risks. The P2
Recognition Project honored three companies in 2007 (http://www.epa.gov/oppt/
newchems/pubs/p2.htm) that provided new, less polluting, innovative chemistries
and processes:
O
BASF Corp. (http://www.epa.gov/oppt/newchems/pubs/basf.htm)
O
Chisso America, Inc. (http://www.epa.gov/oppt/newchems/pubs/chisso.htm)
O
Clariant Corp. (http://www.epa.gov/oppt/newchems/pubs/clariant.htm)
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•	An innovative approach is encouraging companies to "pre-screen" their chemical
submissions: Those who submit low-hazard, low-risk new chemical notices may
receive an expedited review, if they have pre-screened the chemical for hazard and
risk concerns using the Sustainable Futures (SF) models (http://www.epa.gov/
oppt/sf/).
From January 2007 through June 2008, in EPA's New Chemicals Program 114 PMNs
were "self-assessed" using Sustainable Futures models, which accounted for
approximately 11 percent of the 1,071 PMN submissions received during this period.
More than 56,000 chemicals were screened using the PBT Profiler during this same
period of time. The PBT Profiler, one of the Sustainable Futures models, estimates
potential for persistence, bioconcentration potential in the environment and aquatic
toxicity, and warns users when the PBT characteristics exceed Agency PBT criteria.
The PBT Profiler can be used to evaluate both new and existing chemicals.
•	From January 2007 through June 2008, 22 new chemical submissions for nanoscale
materials were submitted to and reviewed by OPPT or are in the review process.
Nanoscale materials are chemical substances at dimensions of roughly 1 to 100
nanometers that may have novel properties that enable applications that differ from
the same materials at a larger scale. To assist potential PMN submitters, EPA has
developed a document, TSCA Inventory Status of Nanoscale Substances—General
Approach (2008) (http://www.epa.gov/oppt/nano/nmsp-inventorypaper2008.pdf),
describing EPA's current thinking regarding whether a nanoscale material is a "new"
or "existing" chemical substance under TSCA. Read the nanoscale materials section
of this report for more information on OPPT's chemicals work on nanoscale materials.
New Biotechnology Products
The New Chemicals Program (NCP) is also home to the Toxic Substances Control Act (TSCA)
Biotechnology Program (http://www.epa.gov/biotech_rule/). This program is responsible for
the safe commercial introduction of new or intergeneric (http://www.epa.gov/biotech_rule/
pubs/biorule.htm) microorganisms with industrial applications, such as bioremediation, or
the production of specialty enzymes.
EPA published final rules on Microbial Products of Biotechnology in 1997 that fully
implemented its screening program for new microorganisms under Section 5 of TSCA
(http://www.epa.gov/biotech_rule/pubs/submain.htm). These regulations create a reporting
vehicle specifically designed for intergeneric microorganisms, the Microbial Commercial
Activity Notice (MCAN).
The rules also address microorganisms used in research and development for commercial
purposes and create a vehicle for reporting on the testing of new microorganisms in the
environment, a TSCA Experimental Release Application (TERA). In recognition of the needs
of researchers, TERA is designed to provide a high measure of flexibility and a shorter
review period.
EPA reviews MCAN and TERA submissions, working closely at times with the submitters, to
ensure the microorganisms do not present an unreasonable risk to human health or the
environment. Since 1997, EPA has received and reviewed 20 MCANs. Based on review of
information provided in the MCANs, EPA determined that these submissions did not warrant
regulation because they were not expected to pose an unreasonable risk or have substantial
or significant exposure. Since 1997, EPA has also received and approved 20 TERAs.
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Accomplishments
•	In 2007, EPA received two MCANs for individual microorganisms—modified
Trichoderma reesei strains with enhanced ability to synthesize cellulose-degrading
and other enzymes—as well as one consolidated MCAN covering six different
modified organic acid producing microorganisms. EPA determined that these
submissions did not warrant regulation and as a result the companies were able to
begin commercialization.
•	In 2007, EPA received and approved, based on the conditions described by the
submitter, one TERA for a modified Pseudomonas putida strain for use in a contained
biosensor device for the detection of trichloroethylene in the environment, using
bioluminescence.
Read more information on the TSCA Biotechnology Program: http://www.epa.gov/
biotech_rule/.
International Efforts
OPPT has continued to be involved in international chemical risk assessment and
management by working with international organizations and through collaborative efforts
with countries and stakeholders. OPPT provides leadership to help other governments,
industry and the public make informed chemical decisions. Sharing and receiving chemical
data and assessments helps leverage scarce resources here and in other countries.
OPPT scientists participate in the Organization for Economic Cooperation and Development
(OECD) Test Guidelines Program (http://www.oecd.org/department/
0,3355,en_2649_34377_l_l_l_l_l,00.html) to develop protocols for studies to assess
physicochemical properties, environmental fate, ecotoxicity, and health effects endpoints.
The OECD is an international organization consisting of 30 industrialized countries in
Europe, North America, Asia, and the Pacific. A foundation of the OECD chemicals program
is the Mutual Acceptance of Data (MAD) agreement among OECD countries to accept for
review studies generated in accordance with OECD Test Guidelines and Principles of Good
Laboratory Practice regardless of where the study is performed in or among OECD
countries.
OPPT continues to participate in the work of the OECD New Chemicals Task Force
(http://www.oecd.Org/department/0,3355,en_2649_34799_l_l_l_l_l,00.html). This work
includes further development of a database to generate a consolidated new chemicals
notification form that integrates the reporting elements from all OECD countries. It also
includes further work to develop a "parallel" review process with other OECD countries,
development of OECD new chemicals working definitions, exemptions and reduced
notification approaches.
Accomplishments
•	Five OECD countries have provided their new chemicals notification forms
(approximately 60 in all) to the OECD New Chemicals Task Force, the reporting
elements of which will be cataloged and used to develop the OECD's New Chemicals
consolidated electronic notification software. The participating countries are Korea,
Japan, Canada, Australia, and the United States.
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•	OPPT participated with other governments in a parallel review process of five new
chemical submissions to explore the concept of Mutual Acceptance of Notifications
among OECD countries. This process was created in recognition of the benefits to
government, industry and the environment of efforts to better align systems for
review of new chemicals in the global market.
•	OPPT participated in a polymer workgroup under the OECD New Chemicals Task
Force, which was convened in 2007. This workgroup collected test data on polymers
of low concern from all participating countries, the results of which were included in
a draft report to OECD's New Chemicals Task Force. The objective was to confirm the
polymer exemption criteria used by countries such as the United States, Canada, and
Australia.
•	In conjunction with the Department of Commerce and U.S. industry stakeholders,
EPA hosted digital videoconferences on chemical risk management to share insights
and practical applications with other countries, including the Philippines'
Environmental Management Bureau (EMB) in 2007.
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Managing Existing Chemicals
¦
r m
I *



Working under authorities
and requirements of the
Toxic Substances Control Act
(TSCA), EPA's existing
chemicals programs gather
and review data, assess risk
and regulate chemicals in
commerce. For example,
under TSCA, EPA can require
companies (manufacturers, importers and processors) to
conduct testing on selected chemicals for which data are
needed to evaluate potential health or environmental
hazards. Such data development requirements may be
established through a test rule (regulation) or through an
Enforceable Consent Agreement (ECA), which is negotiated
among interested parties and generally provides an alternative to formal rulemaking.
Strategic Plan
One of the targets in "Goal
Four" of EPA's Strategic Plan is
to achieve a 26 percent
cumulative reduction of chronic
human health risk from
environmental releases of
industrial chemicals in
commerce since 2001, as
measured by EPA's "Risk
Screening Environmental
Indicators" model. The plan
foresees this target being met
by 2011.
TSCA gives EPA responsibility to maintain the TSCA Inventory containing more than 83,000
chemicals. As new chemicals are manufactured, they are placed on the list.
Under TSCA Section 5, EPA may promulgate a Significant New Use Rule (SNUR), when it
identifies a "significant new use" that could result in exposures to, or releases of, a
substance of concern. Under SNURs, subject entities must give EPA a 90-day advance notice
of their intent to manufacture, import, or process a chemical for a significant new use. The
required notice provides EPA with the opportunity to evaluate intended new uses and
associated activities and, if necessary, prohibit or limit those uses and activities before they
occur.
Over the last several years, OPPT's work to ensure the safety of existing chemicals has
focused on making basic hazard information available to the public on the approximately
2,200 High Production Volume (HPV) chemicals for which manufacturers and importers
pledged to provide information. HPV chemicals are produced and/or imported in annual
volumes of 1 million pounds or greater per year. The HPV Challenge Program
(http://www.epa.gov/hpv/) has made chemical data and assessments accessible to the
public to help industry and citizens make wise chemical choices.
This information has become the basis for a larger effort to evaluate and initiate risk
management actions as appropriate on both high- and moderate-production volume
chemicals—a commitment OPPT made in 2007.
Accomplishments
• EPA has broadened its efforts to ensure the safety of existing chemicals with the
creation of the Chemical Assessment and Management Program (ChAMP)^S1
(http://www.epa.gov/champ/).
1 [23EPA no longer updates this information but it may be useful as a reference or a resource.
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ChAMP is implementing commitments the United
States made at the Security and Prosperity
Partnership of North America (SPP) Leaders'
Summit (http://www.spp.gov/), in Montebello,
Canada, August 2007, which builds on EPA's
efforts under the High Production Volume (HPV)
Challenge Program (http://www.epa.gov/hpv).
The new commitments include completing
screening-level characterizations and taking
action, as needed, by 2012 on high- and
moderate-production volume (MPV) chemicals,
which are those produced at quantities greater than or equal to 25,000 pounds per
year—an estimated 6,750* chemicals.
•	In announcing ChAMP at the March 2008 "Global Chemical Regulation Conference,"
former Administrator Stephen L. Johnson stated in his keynote speech
(http://yosemite.epa.gov/opa/admpress.nsf/8d49f7ad4bbcf4ef852573590040b7f6/
a47e97b97a782c48852574100048ddd9!OpenDocument) that EPA would engage
stakeholders to discuss potential enhancements (http://www.epa.gov/champ/
pubs/programs.htm) to ChAMP, including an HPV Challenge-type program for HPV
inorganic chemicals, and "resetting" the TSCA inventory to update it to reflect the
chemicals currently in use.
EPA held a series of ChAMP stakeholder meetings, including a public meeting May 2,
2008, to encourage input from stakeholders on meeting the SPP goals by 2012 and
the potential program enhancements. EPA is evaluating the stakeholder input and
plans to have recommendations for whether and how to proceed by the end of the
summer 2008.
•	By June 2008, EPA posted on its Web site hazard characterizations for 275 HPV
chemicals. EPA began the effort in 2007 to give the public an objective evaluation of
the quality and completeness of data gathered through the HPV Challenge Program.
In 2007, EPA also began creating screening-level exposure characterizations and risk
characterizations to assemble data needed to produce initial risk-based prioritizations
on HPV chemicals.
By June 2008, EPA posted initial risk-based prioritizations for 19 HPV chemicals to its
Web site, and will continue to develop and post prioritizations for additional
chemicals. The plan is for the ChAMP program to encompass initial prioritizations for
potential actions, as needed, for both HPV and MPV chemicals.
For more information on this work, read the ChAMP section of this report. For
information on the progress of these documents, visit the ChAMPH32 Web site
(http://www.epa.gov/champ/).
•	To reach goals under SPP, OPPT also began working with counterparts in
Environment Canada and Health Canada to identify areas of mutual interest in
existing chemicals assessment and management. This work will continue in 2008.
Announcement
The Chemical Assessment and
Management Program (ChAMP)
has been superseded by the
comprehensive approach to
enhancing the Agency's current
chemicals management program
announced by Administrator Lisa
Jackson on September 29, 2009
(http://www.epa.gov/oppt/existing
chemicals).	
1	Based on preliminary statistics from 2006 IUR data.
2	E3EPA no longer updates this information but it may be useful as a reference or a resource.
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The chemical cooperation agreement under SPP calls for the United States, Canada,
and Mexico to develop a regional partnership to work cooperatively on science-based
risk assessment and risk management of chemicals in commerce.
•	On October 9, 2007, EPA issued a final SNUR (http://www.epa.gov/fedrgstr/
EPA-TOX/2007/October/Day-09/tl9828.htm) for 183 perfluoroalkyl sulfonate (PFAS)
chemicals that were not included in prior perfluorooctyl sulfonate (PFOS)-related
SNURs.
Public comments on the 2006 proposed SNUR resulted in information about ongoing
uses of some PFAS chemicals in the surface-finishing industry; therefore, the final
SNUR contains exclusions for those uses.
•	On October 5, 2007, EPA issued a final SNUR (http://www.epa.gov/fedrgstr/
EPA-TOX/2007/October/Day-05/tl9705.htm), based on a 2006 proposal, for
elemental mercury (http://www.epa.gov/mercury/snur.htm) used in convenience
light switches, anti-lock braking system (ABS) switches, and active-ride-control-
system switches in certain motor vehicles.
For related information, visit Existing Chemicals (http://epa.gov/oppt/existingchemicals),
Chemical Testing & Data Collection (http://www.epa.gov/oppt/chemtest/index.html) and
the HPV Challenge Program (http://www.epa.gov/hpv/).
HPV Challenge Program
The purpose of the High Production Volume (HPV) Challenge
Program is to ensure that basic health and environmental
effects data on HPV chemicals are made available to the
public. HPV chemicals are considered to be those
manufactured or imported in amounts equal to or greater
than 1 million pounds per year. A basic premise of the
program is that the public has a right to know about the
hazards associated with chemicals in their environment and
that this information helps them to make wise choices in
selecting which chemicals or consumer products to use.
EPA is expanding its HPV Challenge Program work and is
extending its efforts to moderate production volume (MPV)
chemicals. These efforts will be implemented under the new
Chemical Assessment and Management Program (ChAMP)^
(http://www.epa.gov/champ/). For more information about
this program, read the ChAMP section of this report.
Since the HPV Challenge Program's inception in 1998,
industry chemical manufacturers and importers have
participated by sponsoring nearly 2,250 chemicals. Sponsorship involves a commitment to
develop data summaries of relevant existing information and to conduct testing to fill any
data gaps. More than 350 companies and 100 consortia have sponsored 1,386 chemicals
directly in the program, and an additional 857 chemicals have been sponsored indirectly in
an international counterpart to the HPV Challenge Program: the International Council of
1 E3EPA no longer updates this information but it may be useful as a reference or a resource.
Strategic Plan
Under Goal Four of EPA's
Strategic Plan, EPA has
committed, by 2011, to
eliminate or effectively
manage risks associated with
100 percent of High
Production Volume (HPV)
chemicals for which
unreasonable risks have been
identified through EPA risk
assessments. (Baseline: EPA
screening of data obtained
through the HPV Challenge
i Program commenced in 2006;
actions to obtain additional
information needed to assess
risks will commence as
chemicals are identified as
priority concerns through the
screening process.)	
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Chemical Associations (ICCA) HPV Initiative. EPA issued an interim report entitled Status
and Future Directions of the High Production Volume (HPV) Challenge Program
(http://www.epa.gov/hpv/pubs/general/hpvstatr.htm) in November 2004 that includes
background and a description of the program.
In an effort to increase accessibility to HPV data, OPPT launched the HPV Information
System (HPVIS) (http://www.epa.gov/hpvis/) Web database in 2006 to allow users to easily
and comprehensively search for specific HPV chemical property data, and OPPT continues its
effort to fully populate the Web database.
OPPT also has contributed to the development and release of the Organization for Economic
Cooperation and Development's eChemPortal (http://www.oecd.org/ehs/eChemPortal),
which also provides public access to information on the properties, hazards and risks of
chemicals.
For more information on these information systems, read the HPVIS and International Work
sections of this report and visit HPVIS (http://www.epa.gov/hpvis/) and eChemPortal
(http://www.oecd.org/ehs/eChemPortal).
Accomplishments
•	In 2007, EPA began focusing its efforts on how to use the collected HPV Challenge
Program data by developing screening-level hazard characterizations. These hazard
characterizations give the public an objective evaluation of the quality,
completeness, and significance of the data. By June 2008, the Agency posted hazard
characterizations for 275 chemicals to its Web site.
In addition to hazard characterizations, in 2007, EPA began developing screening-
level exposure characterizations and risk characterizations that were used to produce
initial risk-based prioritization documents for HPV chemicals. By June 2008, the
Agency posted risk-based prioritizations for 19 chemicals to its Web site and will
continue to develop and post prioritizations for additional chemicals.
In March 2008, EPA created the Chemical Assessment and Management Program
(ChAMP), broadening its HPV Challenge Program and extending its efforts to include
moderate production volume chemicals, which are those produced in quantities
greater than 25,000 pounds and less than 1 million pounds per year. ChAMP is the
program that encompasses hazard characterizations and prioritizations on chemicals
for possible risk management actions. Read the ChAMP section of this report for
more information about the program. For information on the progress of these
documents, visit the ChAMP®1 Web site (http://www.epa.gov/champ/).
•	As part of its HPV Challenge Program and HPVIS database outreach, EPA staffed a
booth in 2007 at conferences, including the Society of Toxicology conference in
Charlotte, N.C., and the Society of Environmental Toxicology and Chemistry
conference in Milwaukee, Wise.
•	By the end of June 2008, data for 1,008 of the approximately 1,400 chemicals
sponsored directly in the program had been entered into HPVIS. Read the HPVIS
section of this report for more information.
EaEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 2

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•	The Agency is currently addressing 15 chemicals that have been sponsored but for
which test plans or completed data summaries have not been submitted to EPA.
To further address "orphan" chemicals (http://www.epa.gov/hpv/pubs/general/
regactions.htm) that were eligible for sponsorship but are not sponsored, EPA
developed a second HPV test rule in 2007, and this proposed rule is scheduled for
publication in 2008.
•	Data are also being developed from industry for an additional 208 orphan chemicals
covered under the TSCA 8(a) Preliminary Assessment Information Reporting (PAIR)
and TSCA 8(d) Health and Safety Data Reporting Rules (http://www.epa.gov/
fedrgstr/EPA-TOX/2006/August/Day-16/tl3479.htm) that were published in 2006.
The Agency has received PAIR reports for 86 of the 208 chemicals, and has received
health and safety study submissions for 54 of the 208 chemical substances; for both
rules, EPA is evaluating the collected information.
Read more information on the HPV Challenge Program (http://www.epa.gov/hpv) and on
HPVIS (http://www.epa.gov/hpvis).
HPVIS—Making HPV Available Online
The High Production Volume Information System (HPVIS) was developed to assist in the
collection, review and reporting of High Production Volume chemicals. The information
contained in HPVIS provides critical basic information about the environmental fate and
potential hazards associated with these chemicals.
HPVIS contains data on more than 50 endpoints organized into the following four endpoint
areas:
•	Physical/chemical properties (e.g., melting point, vapor pressure);
•	Environmental fate and pathways (e.g., biodegradation, stability in soil);
•	Ecotoxicity (e.g., fish toxicity, toxicity to terrestrial plants); and
•	Mammalian health effects (e.g., reproductive toxicity, developmental toxicity).
When combined with information about exposure and uses (e.g., from the Inventory Update
Reporting rule), the HPVIS data will enable EPA and others to evaluate potential health and
environmental hazard and exposure and identify priorities for appropriate follow-up action.
Accomplishments
•	EPA's HPVIS database has been on the Web for public use since April 2006. As of
June 2008, HPVIS contained 360 submissions, representing 1,008 chemical
substances, either as a single chemical submission or as a member of a chemical
category.
•	The first hazard characterizations (HCs) were posted in September 2007. HCs are
EPA's characterization of screening-level hazard data submitted to the Agency on
high-production volume chemicals through the HPV Challenge Program. While
screening-level HCs provide a vehicle for public access to more than raw technical
data on the hazards of HPV chemicals, they are not an evaluation of the potential
risks of a chemical. Each HC includes:
OPPT Accomplishments Report January 2007 - January 2009
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o A summary of submitted data,
o EPA's evaluation of the quality and completeness of the data, and
o EPA's determination of the potential hazards a chemical or chemical category
may pose to human health or the environment.
•	By June 2008, hazard characterizations for 275 chemicals were posted.
•	EPA began developing initial risk-based prioritization documents, which are
screening-level documents that summarize basic hazard and exposure information
on HPV chemicals, identify potential risks, note scientific issues and uncertainties,
and indicate the initial priority for potential future action by the Agency.
•	In March 2008, EPA created the Chemical Assessment and Management Program
(ChAMP))®1 (http://www.epa.gov/champ/), broadening the efforts of the HPV
Challenge Program and extending the Agency's work to encompass hazard
characterizations and prioritizations for moderate production volume chemicals
produced in quantities of 25,000 pound per year to 1 million pounds per year, in
addition to data on HPV chemicals.
By June 2008, the Agency posted to its HPVIS Web site risk-based prioritizations for
19 chemicals, and will continue to develop and post prioritizations for additional
chemicals. For more information on this work, read the ChAMP section of this report.
For information on the progress of these documents, visit the ChAMP®1 Web site
(http://www.epa.gov/champ/).
•	EPA held two regional workshops (http://www.epa.gov/hpv/meetings/regmtgs.htm)
as a follow-up to the first HPV Data Users Conference, "Characterizing Chemicals in
Commerce," held December 12-14, 2006, in Austin, Texas (http://www.epa.gov/
hpv/meetings/chemdataconf.htm). The workshops were attended by approximately
45 attendees representing state and EPA officials, industry representatives and
academic researchers.
Attendees learned about the EPA HPV Challenge Program, shared experiences about
uses of HPV data and developed ideas on how agencies and programs in the EPA
regions could use this data.
o The first workshop took place on June 14, 2007 in Tyngsboro, Massachusetts.
o The second workshop took place on September 27, 2007 in Atlanta, Georgia.
Read more information on the High Production Volume Information System (HPVIS):
http://www.epa.gov/hpvis. OPPT has contributed to the development and release of a
similar database, the Organization for Economic Cooperation and Development's
eChemPortal (http://www.oecd.org/ehs/eChemPortal), which also provides public access to
information on the properties, hazards and risks of chemicals. Read more information about
the eChemPortal in the International Work section of this report.
Inventory Update Reporting
EaEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 4

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The aim of the Inventory Update Reporting (IUR) (http://www.epa.gov/oppt/iur/) program
is to collect the highest quality screening-level, exposure-related information and to make
that information available to EPA and the public.
Chemical manufacturing, processing and use information is reported to EPA under the IUR
rule, amended in 2003 and issued under the Toxic Substance Control Act (TSCA).
Manufacturers and importers of—at current estimates—7,500 organic and inorganic
chemicals report basic manufacturing information for chemicals produced in volumes of
25,000 pounds or more at a site. To put this in perspective, that is out of the more than
83,000 chemicals listed on the TSCA Chemical Substances Inventory (http://www.epa.gov/
oppt/newchems/pubs/invntory.htm). For chemicals produced or imported in volumes of
300,000 pounds or more at a site, manufacturers also report processing and use
information.
The most comprehensive source of basic screening-level, exposure-related information, the
IUR data are used to support risk screening, assessment, priority setting and management
activities.
Accomplishments
•	During 2007, EPA completed the first IUR collection (called the 2006 IUR) since
major amendments to the IUR were published in 2003 (http://www.epa.gov/
fedrgstr/EPA-TOX/2003/January/Day-07/t32909.pdf). To provide additional time for
industry reporting, EPA extended the 2006 IUR submission period to March 2007.
EPA received updated information for approximately, at current estimates, 7,500
organic and inorganic chemicals for the 2006 IUR. For the first time, this information
included:
o Manufacturing information for inorganic chemicals,
o Enhanced manufacturing information for organic chemicals (e.g., the physical
form of the chemical and the number of potentially exposed workers), and
o Additional screening-level exposure-related processing and use information
for organic chemicals produced at 300,000 pounds or greater at a single site.
•	The Agency is using 2006 IUR exposure data in conjunction with hazard and fate
data received under the High Production Volume Challenge Program
(http://www.epa.gov/hpv) to develop screening-level documents summarizing basic
hazard and exposure information on HPV chemicals.
This effort, through the Chemical Assessment and Management Program (ChAMP)
M1 (http://www.epa.gov/champ/), is helping to fulfill EPA's commitments made in
August 2007 under the Security and Prosperity Partnership (http://www.spp.gov).
The screening-level documents will include evaluations identifying potential risks,
noting scientific issues and uncertainties, and indicating the initial priority being
assigned by the Agency for action, where appropriate. For more information on this
effort, see the HPV, HPV Information System, and ChAMP sections of this report.
EaEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 5

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• EPA launched a new IUR information management system in 2007, consolidating
information submitted to EPA online using EPA's Central Data Exchange (CDX)
(http://www.epa.gov/cdx/), on CDs and in hard copy. The new information system
provides improved access to IUR information for Agency data users to make
regulatory and risk management decisions. Currently, the system is only accessible
to Agency users because it contains Confidential Business Information (CBI). A sub-
set of the non-CBI data will be made available to the public in the future.
In an effort to ensure the data entered into the IUR information management system
are as complete and correct as possible, EPA used rigorous quality control methods
when populating this system, including contacting submitters with questions
concerning their IUR reports, checking chemical names and identifying information,
etc.
Read more information on the Inventory Update Reporting program:
http://www.epa.gov/oppt/iur.
ChAMP
The Chemical Assessment and Management Program (ChAMP)!?!1 (http://www.epa.gov/
champ/) is aimed at broadening EPA's efforts to ensure the safety of existing chemicals. The
program is increasing the number of chemicals for which EPA is making screening-level risk
and hazard characterizations available to the public, and will be using the data to prioritize
and categorize the chemicals as to whether additional control measures are needed to
address potential risks.
ChAMP was created to implement commitments the United States made at the Security and
Prosperity Partnership of North America (SPP) Leaders' Summit, in Montebello, Canada, in
August 2007 (http://www.spp.gov).
These commitments build on EPA's efforts under the High Production Volume (HPV)
Challenge Program (http://www.epa.gov/hpv), which is making health and environmental
effects data publicly available on chemicals produced or imported in the United States in
quantities of 1 million pounds or more per year. ChAMP extends this effort to include
moderate-production volume chemicals.
ChAMP will implement the U.S. commitment under SPP to complete, by 2012, screening-
level risk characterizations and initiate action, as appropriate, on high- and moderate-
production volume chemicals (MPV) produced at quantities greater than or equal to 25,000
pounds per year. These are estimated to number 6,750, based on preliminary statistics
from 2006 Inventory Update Reporting (http://www.epa.gov/oppt/iur) data.
EPA is also communicating with stakeholders regarding the possibility of initiating, through
ChAMP, an HPV Challenge-type program for HPV "inorganic" chemicals, and "resetting" the
Toxic Substances Control Act (TSCA) Inventory to update it to accurately reflect the
chemicals that are currently being used in commerce.
EPA's Hazard-Based Prioritizations (http://www.epa.gov/champ/pubs/hbpdocs.htm) are
screening-level documents prepared on moderate production volume (MPV) chemicals that:
EaEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 6

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Summarize and assess hazard information
•	Consider quantitative structure-activity relationship (Q)SAR estimates
•	Consider Canada's categorization results in developing an initial screening-level
assessment of the potential health and environmental hazards and fate of MPV
chemicals
•	Note scientific issues and uncertainties
•	Indicate the initial priority being assigned by the Agency for potential future
appropriate action
Former EPA Administrator Stephen L. Johnson announced the creation of ChAMP in his
keynote speech at the "Global Chemical Regulation Conference" in Baltimore, MD, in March
2008. He said EPA would begin talking to a wide range of stakeholders on possible
enhancements to ChAMPUl1 (http://www.epa.gov/champ/pubs/programs.htm), including
the HPV Challenge-type program for HPV inorganic chemicals and "resetting" the TSCA
inventory.
Accomplishments
•	EPA held a series of stakeholder meetings, including a public meeting on May 2,
2008, to encourage input from stakeholders on development of ChAMPH1
(http://www.epa.gov/champ/) initiatives, including:
o Meeting SPP goals by 2012,
o Developing an HPV Challenge-type program for "inorganic" HPV chemicals,
and
o Options to potentially reset the TSCA Inventory.
EPA is evaluating the stakeholder input and plans to have recommendations for
whether and how to proceed by the end of the summer 2008.
•	By June 2008, the Agency posted hazard characterizations for 275 chemicals to its
Web site and posted risk-based prioritizations for 19 HPV chemicals. Based on
experience developing this first set of prioritizations and feedback received from
stakeholders, EPA has streamlined the preparation of, and improved the presentation
of, information within the prioritizations.
EPA is actively developing prioritizations for additional chemicals and expects to
complete prioritizations for an additional 200 high- and moderate-production volume
chemicals in 2008. For information on the progress of these documents, visit the
ChAMPHS1 Web site (http://www.epa.gov/champ/).
•	On September 24, 2008, EPA outlined enhancements to ChAMP®1
(http://www.epa.gOv/champ/pubs/programs.htm#enhancements), including a reset
of the TSCA Inventory (http://www.epa.gov/oppt/newchems/pubs/invntory.htm) and
collecting health and safety information on inorganic high-production volume
EzlEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 7

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chemicals. EPA also held a public meeting on December 8, 2008 to further engage
stakeholders on these enhancements.
•	On November 6, 2008, EPA posted a Risk Based Prioritization document for
elemental mercury in certain products and substitutes (http://www.epa.gov/hpvis/
rbp/Mercury_RBP_10.31.08_FINAL.pdf), and determined that mercury in these
products poses a "high priority, special concern."
•	As of December 2008, EPA had developed and posted risk-based prioritizations for
151 HPV chemicals and had posted hazard-based prioritizations for 55 chemicals.
Read more information on SPP (http://www.spp.gov) and ChAMPH1 (http://www.epa.gov/
champ/), as well as other sections of this report on HPV, HPVIS, International Work, and the
Strategic Approach to International Chemicals Management (SAICM).
Chemical Nanoscale Materials
OPPT is evaluating and, where appropriate, managing the risks associated with engineered
nanoscale materials (http://www.epa.gov/oppt/nano/). Nanoscale materials at dimensions
of roughly 1 to 100 nanometers may exhibit novel properties that enable applications that
differ from the same materials at a larger scale. A nanometer is about one ten-thousandth
the diameter of a human hair.
Nanoscale materials (NMs) that are "chemical substances" as defined under the Toxic
Substances Control Act (TSCA) are subject to the law unless otherwise excluded. Thus TSCA
pre-manufacture notifications (PMNs) (http://www.epa.gov/oppt/newchems/pubs/
whatinfo.htm) are required to be submitted to EPA prior to manufacturing a "new" NM, i.e.,
a NM that is not currently listed on the TSCA Chemical Substances Inventory
(http://www.epa.gov/oppt/newchems/pubs/invntory.htm). The Agency will take steps to
control or limit exposures to these NMs, and may require testing to generate health and
environmental effects data where appropriate.
To assist potential PMN submitters, EPA has developed a document, TSCA Inventory Status
of Nanoscale Substances—General Approach (2008) (http://www.epa.gov/oppt/nano/
nmsp-inventorypaper2008.pdf), describing EPA's current thinking regarding whether a
nanoscale material is a "new" or "existing" chemical substance under TSCA. This document
was published for public review and comment prior to its release in January 2008.
On January 28, 2008, OPPT initiated a Nanoscale Materials Stewardship Program (NMSP)
(http://www.epa.gov/oppt/nano/stewardship.htm) aimed at gathering currently available
information on NMs. Its goal is to help provide a firmer scientific foundation for regulatory
decisions by encouraging submission and development of key scientific information,
including risk-management practices for nanoscale materials. Companies that manufacture,
import, process, or use nanoscale materials for commercial purposes, as well as
researchers, were invited to participate. On January 12, 2009, EPA released its interim
report on the status of the NMSP and possible next steps (http://www.epa.gov/oppt/nano/
nmsp-interim-report-final.pdf).
OPPT chairs and is actively participating in the Organization for Economic Cooperation and
Development's (OECD) Working Party on Manufactured Nanomaterials
EaEPA no longer updates this information but it may be useful as a reference or a resource.
OPPT Accomplishments Report January 2007 - January 2009	' 8

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(http://www.oecd.Org/document/30/0,3343, en_2649_34269_40047134_l_l_l_l, 00. html)
and its projects to further understanding of the properties and potential risks of
nanomaterials.
Accomplishments
•	As of July 8, 2008, four companies submitted information, and ten companies and
two trade associations committed to submit information under the basic program of
the Nanoscale Materials Stewardship Program (NMSP). Read the most current
information on program participants (http://www.epa.gov/oppt/nano/
stewardship.htm#participants). EPA has encouraged participants in the basic
program to submit existing data by July 28, 2008.
OPPT announced a variety of opportunities for public input (http://www.epa.gov/
oppt/nano/stewardship.htm) on the program's development in 2007, including a
request for comments on: a paper outlining the Agency's initial concept; an
information collection request; and other materials connected to the program.
•	OPPT and EPA's Office of Research and Development (ORD) hosted the Pollution
Prevention Through Nanotechnology Conference, September 25-26, 2007
(http://www.epa.gov/opptintr/nano/agenda.htm), to exchange ideas and information
on using nanotechnology to prevent pollution.
•	OPPT and ORD co-chaired the development of an EPA Nanotechnology White Paper
(http://www.epa.gov/osa/pdfs/nanotech/epa-nanotechnology-whitepaper-0207.pdf),
which was issued in February 2007, describing why EPA is interested in
nanotechnology across its programs, the Agency's statutory mandates, and risk
assessment issues specific to nanotechnology across media.
•	With EPA in the lead, the OECD's Working Party on Manufactured Nanomaterials
(http://www.oecd.Org/document/30/0,3343,en_2649_34269_40047134_l_l_l_l,0
O.html) launched a "sponsorship program" for countries to share testing information
on the human health and environmental safety of a representative set of 14
manufactured nanomaterials. The OECD Secretariat asked delegations to sponsor or
co-sponsor one or more nanomaterials and endpoints. As part of its commitments,
EPA is sponsoring environmental effects and fate testing of fullerenes, single-walled
carbon nanotubes, multi-walled carbon nanotubes, and cerium oxide, and is
encouraging participation by other U.S. entities in the OECD work.
Managing Potential PFOA Risks
Perfluorooctanoic acid (PFOA) is a persistent, man-made chemical that animal studies have
shown can cause systemic and developmental toxicity. It has been found in human blood
and it remains in the body for years. The Office of Pollution Prevention and Toxics (OPPT)
began investigating PFOA in 2002 to determine the risk it may pose to humans and the
environment and what, if any, actions could be taken.
OPPT has taken action to help minimize the potential impact of PFOA and related chemicals
on the environment. In January 2006, former EPA Administrator Stephen Johnson initiated
the 2010/15 PFOA Stewardship Program (http://www.epa.gov/oppt/pfoa/pubs/
stewardship/index.html), in which eight major companies in the industry committed to
voluntarily reduce facility emissions and product content of PFOA and related chemicals on
both a domestic and a global basis by 95 percent no later than 2010, and to work toward
eliminating emissions and product content of these chemicals by 2015. Companies
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submitted their baseline year emissions and product content data (http://www.epa.gov/
oppt/pfoa/pubs/stewardship/sumrpt.html) in October 2006. Progress reports
(http://www.epa.goV/oppt/pfoa/pubs/stewardship/preports2.html#background) are due
annually on October 31.
OPPT and EPA's Office of Enforcement and Compliance Assurance work together to take
enforcement actions under TSCA when necessary. Two such significant actions in connection
with PFOA were the $10.25 million settlement between EPA and DuPont
(http://www.epa.gov/compliance/resources/cases/civil/tsca/dupontl21405.html) reached in
December 2005 and the $1.5 million settlement between EPA and the 3M Company
(http://www.epa.gov/compliance/resources/cases/civil/tsca/3m.html) reached in April
2006.
OPPT is a key player in raising awareness on PFOA-related issues internationally working
with the Organization for Economic Cooperation and Development (OECD). For example, the
United States and Germany are developing a draft hazard assessment on PFOA. OPPT also
participated in developing the OECD workshop on PFOA and related chemicals
(http://www.oecd.Org/document/58/0,3343,en_2649_37465_2384378_l_l_l_37465,00. ht
ml).
Accomplishments
•	In August 2007, a U.S. Centers for Disease Control report
(http://www.ehponline.org/docs/2007/10598/abstract.html) showed significant
reductions in human blood levels of perfluorooctyl sulfonates (PFOS) and PFOA from
1999-2000 compared to the most recent data in 2003-2004 in a representative
sample of the U.S. population. The geometric mean for PFOA in human blood was
reduced by 25 percent over this period and PFOS was reduced by 32 percent. The
report concluded that these reductions were most likely related to changes brought
about by EPA efforts on these chemicals and other related efforts by government and
industry.
•	Eight major companies participating in the PFOA Stewardship Program reported
significant drops in the release of PFOA and related chemicals, putting industry on
target to meet the 95 percent reduction goal in PFOA emissions and product content
by 2010. Further reductions are anticipated by 2015. These first annual progress
reports (http://www.epa.gov/oppt/pfoa/pubs/stewardship/preports.html) were
submitted to EPA in October 2007, and were measured against baseline data
(http://www.epa.gov/oppt/pfoa/pubs/stewardship/sumrpt.html) submitted in
October 2006. In February 2008, OPPT released summary tables of 2007 progress
reports (http://www.epa.gOv/oppt/pfoa/pubs/stewardship/preports.html#summary).
In December 2008, OPPT released summary tables of 2008 progress reports
(http://www.epa.g0v/opptintr/pfoa/pubs/stewardship/preports2.html#summary).
•	OPPT entered into two enforceable consent agreements (ECAs)
(http://www.epa.gov/oppt/pfoa/pubs/eca.html) with industry in July 2005 to
determine whether incineration of telomers (http://www.regulations.gov/fdmspublic/
component/main?main = DocketDetail&d = EPA-HQ-OPPT-2004-0001) and
fluoropolymers (http://www.regulations.gov/fdmspublic/component/
main?main = DocketDetail&d = EPA-HQ-OPPT-2003-0071) could be a source of PFOA.
Phase I of the ECA process was successfully completed for both ECAs by the end of
2007. The final reports on incineration results are expected in 2008 and 2009,
respectively.
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As an outgrowth of the ECA process, OPPT is working with ORD to determine
whether telomeric polymers can biodegrade to PFOA and to determine whether
fluoropolymer and telomer-treated articles can release PFOA as they age.
•	In October 2007, OPPT issued a final Significant New Use Rule (SNUR) for 183
perfluoroalkyl sulfonate (PFAS) chemicals (http://www.epa.gov/fedrgstr/
EPA-TOX/2007/October/Day-09/tl9828.htm) that were not included in prior
perfluorooctyl sulfonate (PFOS)-related SNURs.
•	In 2007, 3M began a peer consultation process (http://www.menziecura.com/pfoa/
index.php), developed under a Memorandum of Understanding (MOU) with the
Agency to assess 3M's environmental monitoring (http://www.regulations.gov/
fdmspublic/component/main?main = DocketDetail&d = EPA-HQ-OPPT-2004-0112) at a
fluoropolymer facility. DuPont also has a similar MOU with the Agency
(http://www. regulations. gov/fdmspublic/component/main?main=DocketDetail&d = EP
A-HQ-OPPT-2004-0113), and has been conducting environmental monitoring
throughout 2007. DuPont's peer consultation process is expected to commence in
2008.
•	EPA continues to monitor DuPont's efforts to develop a method to purify certain
fluorotelomer-based products as part of the Biodegradation Supplemental
Environmental Project (SEP). The Biodegradation SEP is part of the $10.25 million
settlement with DuPont (http://www.epa.gov/compliance/resources/cases/
civil/tsca/dupontl21405.html). The Biodegradation SEP, valued at $5 million, was
designed to investigate the biodegradation potential of certain chemicals to
breakdown to form PFOA. Nine of DuPont's commercial fluorotelomer-based products
in commerce prior to the settlement are being evaluated. Using two types of
biodegradation studies, the SEP will help the public to better understand the inherent
degradation potential of fluorotelomer-based products to form PFOA and the
behavior of such products when released to the environment.
Read more information on the Agency's activities concerning PFOA and related chemicals:
http://www.epa.gov/oppt/pfoa/.
Potential Chemical Risks to Children
Developed through a public stakeholder process, the
Voluntary Children's Chemical Evaluation Program (VCCEP)
(http://www.epa.gov/oppt/vccep/) is helping the public
better understand the potential health risks to children
associated with certain chemical exposures.
VCCEP is a three-tiered assessment program designed to
fully evaluate hazards, exposures and risks of chemicals to
children and to develop information needed to adequately
assess the risks to children. Under VCCEP, EPA collects three tiers of increasingly detailed
information on a chemical's toxicity and exposure and resulting potential risk to children.
So far EPA has asked companies to volunteer to sponsor their chemical(s) for Tier 1. After
completing the evaluation of some Tier 1 chemical assessments, EPA asked companies to
volunteer to sponsor higher tier testing for several chemicals. VCCEP is more an information
collection program than a testing program. Rigorous chemical selection criteria were used to
Strategic Plan
EPA, in its Strategic Plan,
committed to completing data
needs documents for 10 of
these chemicals by the end of
2007; 12 were completed by
December 2007.
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21

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identify 23 chemicals for the pilot program. Companies have agreed to sponsor 20 of the 23
chemicals in the pilot.
Similar to the HPV Challenge Program, the goal of VCCEP is to make data publicly available.
The implementation process builds on and models the HPV Challenge Program whenever
possible.
Accomplishments
•	When VCCEP was announced as a new program in December 2000, EPA committed
to conducting an evaluation of the pilot program approximately mid-way in its
implementation. In 2007, EPA compiled and summarized the responses to its 2006
Request for Comment on the Implementation of the VCCEP pilot, which was
published in the Federal Register (http://www.epa.gov/fedrgstr/
EPA-TOX/2006/November/Day-20/tl9574.htm).
A summary of the comments (http://www.epa.gov/oppt/vccep/pubs/
summaryrpt.pdf) was made available on the VCCEP Web site along with the options
EPA is considering (http://www.epa.gov/oppt/vccep/pubs/interim.html) on future
changes to VCCEP, which focus on enabling VCCEP to operate more rapidly and
efficiently to meet its goals. Adapting the VCCEP approach for the further evaluation
of other HPV chemicals was also explored.
•	From January 2007 through June 2008, EPA issued Data Needs Decisions for seven
chemicals—n-dodecane, undecane, decane, benzene, m-xylene, o-xylene, and
toluene—identifying whether additional hazard and/or exposure information were
needed to adequately assess the potential risks to children and, where relevant,
prospective parents.
In its Data Needs Decisions, EPA determined that additional information was needed
for four of the seven chemicals—benzene, m-xylene, o-xylene, and toluene. By the
end of 2007, the consortium of companies sponsoring benzene, the xylenes, and
toluene declined to conduct the requested upper tier tests for benzene. EPA is still
awaiting the consortium's decision on whether to sponsor upper tier tests for m-
xylene and o-xylene and whether to provide additional occupational and general
population exposure information on toluene.
For the other three chemicals—n-dodecane, undecane, and decane—EPA concluded
that upper tier tests were not needed.
•	In 2007, chemical sponsors submitted a Tier 1 chemical assessment for one
chemical—p-dioxane—totaling 15 chemical assessments received out of the 20
chemicals.
•	In 2007, the sponsors of five chemicals committed to provide additional information
(not new testing) to address transparency and uncertainty issues and to complete
their assessments.
o Sponsors of decabromodiphenyl ether committed to provide additional
information on environmental fate and transport and on the chemical's
breakdown products to complete their Tier 2 assessment.
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o Sponsors of decane, undecane, and n-dodecane committed to provide
additional information on environmental fate and transport to address
transparency and uncertainty issues.
o Sponsors of benzene committed to provide additional information on exposure
and fate to complete their Tier 1 assessment.
•	In 2007, Toxicology for Excellence in Risk Assessment (TERA)—a third party
organization that organizes and facilitates peer consultation meetings to evaluate
VCCEP chemical assessments—held peer consultations for two more chemicals—p-
dioxane and ethylbenzene—and wrote summary reports of meetings for three-
toluene, p-dioxane, and ethylbenzene.
•	In May 2008, EPA terminated sponsorship of decabromodiphenyl ether in VCCEP
because necessary Tier 2 data were not provided.
Read more information on the Voluntary Children's Chemical Evaluation Program (VCCEP):
http://www.epa.gov/oppt/vccep/.
Section 21 Petitions
Under Section 21 of the Toxic Substances Control Act (TSCA), any person may petition EPA
to initiate a proceeding for the issuance, amendment, or repeal of a rule or order under:
•	Section 4—rules requiring chemical testing;
•	Section 6—rules imposing regulatory controls on chemicals;
•	Section 8—rules requiring information;
•	Section 5(e)—orders affecting new chemical substances, or
•	Section 6(b) (2)—orders affecting quality control procedures.
The petition must be filed in EPA's Office of the Administrator, and set forth the facts that
are claimed to establish the necessity for the action requested. EPA is required to grant or
deny the petition within 90 days from the day the petition is filed with EPA. If EPA grants
the petition, EPA must promptly commence an appropriate proceeding. If EPA denies the
petition, the reasons for denial must be published in the Federal Register.
Accomplishments
•	On November 25, 2008, EPA launched a broad effort (http://www.epa.gov/oppt/
chemtest/formaldehyde/) to gain a greater scientific understanding of the potential
health risks of formaldehyde's use in pressed wood products.
In issuing an advance notice of proposed rulemaking (ANPR)
(http://www.epa.gov/fedrgstr/EPA-TOX/2008/December/Day-03/t28585.htm), EPA
initiated a process to develop risk assessments on potential adverse health effects of
formaldehyde, evaluate the costs and benefits of its possible control technologies,
and determine whether EPA action is needed to address any identified risks.
EPA began the effort following its review of a TSCA Section 21 citizens' petition
(http://www.epa.gov/oppt/chemtest/pubs/petition3.pdf) that requested that EPA
adopt nationally a California regulation to control formaldehyde emissions from these
wood products.
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The agency has been holding public meetings (http://www.epa.gov/oppt/chemtest/
formaldehyde/) to get additional stakeholder input.
•	On March 6, 2008, an individual filed a Section 21 petition requesting that EPA
establish regulations prohibiting the use and distribution in commerce of Hevea
brasiliensis natural rubber latex adhesives with relatively high levels of protein. EPA
denied the petitioner's request (http://www.epa.gov/fedrgstr/
EPA-TOX/2008/June/Day-09/tl2850.htm) as unsupported.
•	December 21, 2007, EPA denied a petition (http://www.epa.gov/fedrgstr/
EPA-AIR/2007/December/Day-21/a6176.htm) by the Natural Resources Defense
Council, the Sierra Club and others seeking labeling of ingredients of air fresheners.
Later, EPA sent letters to manufacturers of air fresheners asking for ingredient
information and received the information. Subsequent litigation was dropped, and
currently a Freedom of Information Act (FOI) request is pending for confidential
business information received by EPA.
Read more information about TSCA Section 21: http://www.epa.gov/opptintr/chemtest/
pubs/sect21.html.
Using TSCA Section 8(e)
Section 8(e) of the Toxic Substances Control Act (TSCA) states that, "Any person who
manufactures, processes or distributes in commerce a chemical substance or mixture and
who obtains information which reasonably supports the conclusion that such substance or
mixture presents a substantial risk of injury to health or the environment shall immediately
inform the [EPA] Administrator of such information unless such person has actual
knowledge that the Administrator has been adequately informed of such information."
OPPT screens all TSCA §8(e) submissions, as well as voluntary "For Your Information" (FYI)
submissions (http://www.epa.g0v/oppt/tsca8e/pubs/basicinformation.htm#fyi). The latter
are not required by law, but are submitted by industry and public interest groups for a
variety of reasons. The purpose of EPA's review is to:
•	Identify chemicals for further assessment or testing
•	Refer information of interest to other regulatory authorities and stakeholders
•	Follow-up with submitters regarding risk management actions
•	Provide chemical hazard and exposure information to the Agency and public to aid in
risk assessment and risk management of commercial chemicals
•	Estimate the effects of closely related chemicals
•	Promote pollution prevention through improved understanding of comparative
toxicities
Information from the summaries can also be instrumental in avoiding unnecessary testing.
TSCA §8(e) and FYI submissions are entered into the TSCA Test Submissions (TSCATS)
database (http://yosemite.epa.gov/oppts/epatscat8.nsf/ReportSearch70penForm), a
submission and document tracking system. EPA continues to provide TSCATS information to
the National Library of Medicine for inclusion in the Toxline database and to others to
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maintain various databases. New TSCA §8(e) submissions are available to the public
through EPA's TSCA §8(e) Web page (http://www.epa.gov/oppt/tsca8e/).
Accomplishments
•	More than 500 initial and more than 170 supplemental TSCA §8(e) submissions were
received from January 2007 through June 2008.
•	A review of several hundred studies was completed in 2007 in response to a request
by the Office of Enforcement to evaluate studies for possible violations of TSCA
Section 8(e).
•	Seventy-two voluntary FYI submissions were received and their initial screening
evaluations are in progress.
•	Of the more than 301 TSCA §8(e) information referrals sent from January 2007
through June 2008, 117 related primarily to EPA PFOA program activities.
•	Also during 2007, OPPT continued to develop its database to improve file
management and the review of new submissions.
Read more information on TSCA §8(e): http://www.epa.gov/oppt/tsca8e/.
TSCA 12(b) Export Notifications
The Toxic Substances Control Act (TSCA) Section 12(b) requires EPA to notify importing
countries of the export or the intended export of industrial chemicals or mixtures that are
subject to certain regulatory actions under U.S. law. Approximately 2,000 chemicals come
under this requirement.
As a member of the Organization for Economic Cooperation and Development (OECD), the
United States participates in a Complementary Information Exchange Procedure intended to
help countries coordinate their chemical control activities.
On February 9, 2006 (71 FR 6733) EPA proposed amendments to the TSCA Section 12(b)
export notification regulations (http://www.epa.gov/fedrgstr/EPA-TOX/2006/February/
Day-09/tl797.htm). The final amendments to the regulations (http://www.epa.gov/
fedrgstr/EPA-TOX/2006/November/Day-14/tl9182.htm) were promulgated on November
14, 2006 (71 FR 66234) and a technical correction notice was issued on November 28, 2006
(71 FR 68750: http://www.epa.gov/fedrgstr/EPA-TOX/2006/November/Day-28/
t20148.htm). These amendments:
•	Focused importing governments' attention on chemicals for which EPA has made an
"unreasonable risk" finding under TSCA
•	Reduced overall burden on exporters and the Agency. Amendments include a change
in the current annual notification requirement to a one-time requirement for
exporters of certain chemicals, and a corresponding one-time notification of foreign
governments by EPA
The Agency also issued de minimus concentration levels below which notification would not
be required, as well as other minor amendments that update the EPA addresses to which
export notifications must be sent and that clarify exporters' and EPA's obligations.
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Accomplishments
•	For the period of January 2007 through December 2007, 59 export notifications were
sent to foreign countries.
•	In 2007, OPPT conducted outreach on TSCA Section 12(b) Export Notifications,
including presentations at the American Chemistry Council's Global Chemical
Regulation Conference & Expo and in the Synthetic Organic Chemical Manufacturers
Association's TSCA Fundamentals Webinar Series.
Read more information on TSCA Section 12(b)—"Export Notification" (http://www.epa.gov/
oppt/import-export/pubs/secl2.htm) and the current list of chemical substances subject to
it (http://www.epa.gov/oppt/import-export/pubs/12blist.htm).
International Work
OPPT participates in an array of international work aimed at reducing risks, facilitating the
sound management of chemicals and preventing pollution. Complementing OPPT's domestic
mission, the work ranges from facilitating the exchange of information, for example, on
chemical assessments and risk assessments, to cooperating on the scientific and technical
aspects of international commitments.
A major step forward, the Security and Prosperity Partnership (SPP) of North America
Leaders' Summit (http://www.spp.gov/), resulted in commitments on behalf of the United
States, Canada and Mexico to work together to ensure the safe manufacture and use of
industrial chemicals. Read more about the SPP commitments on chemical cooperation made
by the United States, Canada and Mexico: http://www.epa.gov/champ/pubs/
basic. htm#07commit.
OPPT is fulfilling U.S. commitments made under SPP through EPA's new Chemical
Assessment and Management Program (ChAMP), which builds on EPA's High Production
Volume (HPV) Challenge Program (http://www.epa.gov/hpv) and extends EPA's efforts to
include moderate production volume chemicals.
ChAMP and the SPP work complement the United States' continuing work with Canada and
Mexico under the Commission on Environmental Cooperation (CEC) Sound Management of
Chemicals (SMOC) Working Group (http://www.cec.org/programs_projects/
pollutants_health/project/index.cfm?projectID=25&varlan=english). Together, these North
American efforts comprise a regional approach to implement the Strategic Approach to
International Chemicals Management (SAICM) (http://www.chem.unep.ch/saicm/). SAICM
is an international policy framework to foster the sound management of chemicals.
In addition to SAICM, countries have committed to global partnerships within the United
Nations Environment Program (UNEP) to reduce releases and uses of mercury
(http://www.chem.unep.ch/MERCURY/partnerships/new_partnership.htm). OPPT helped
spearhead this initiative and is leading partnership efforts on mercury in products. EPA's
PFOA Stewardship Program is also making significant progress toward reductions in releases
and use in products both domestically and globally.
OPPT continues its technical, scientific and regulatory cooperation in the Organization for
Economic Cooperation and Development (OECD) (http://www.oecd.org/department/
0,3355,en_2649_34365_l_l_l_l_l,00.html). Over the years, OPPT's work in OECD has
contributed in a significant way to the Screening Data Information Sets (SIDS) program, out
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of which grew EPA's HPV Challenge program (http://www.epa.gov/hpv). Both programs are
giving citizens screening-level hazard data on HPV chemicals, and are, in turn, contributing
to the new ChAMP.
OPPT also provides substantial leadership and international coordination through our
Nanoscale Materials Stewardship Program (NMSP) (http://www.epa.gov/oppt/nano/
stewardship.htm) and participation in the OECD Working Party on Manufactured
Nanomaterials (WPMN).
The Administration supports the United States becoming a party to the:
•	Stockholm Convention on Persistent Organic Pollutants (POPs)
(http://www.pops.int/documents/meetings/cop_3/meetingdocs/report/default.htm),
•	1979 Convention on Long-Range Transboundary Air Pollution (LRTAP) Protocol on
POPs, a regional convention (http://www.unece.org/env/lrtap/welcome.html),
•	1998 Rotterdam Convention on the Prior Informed Consent (PIC) Procedure for
Certain Hazardous Chemicals and Pesticides in International Trade
(http://www.pic.int/home.php?type=t&id = 5&sid=16)
Both the Stockholm Convention on POPs and the LRTAP Protocol on POPs include provisions
that require parties to eliminate or restrict the production, use and/or release of the POPs
chemicals listed under the respective Agreements. In general, POPs under these
Agreements are chemicals that are persistent and toxic, can bioaccumulate and be
transported long distances in the environment, and are likely to affect human health or the
environment in locations distant from their sources.
The United States is a party to the United Nations Economic Commission for Europe LRTAP
Convention, including the Protocol on Heavy Metals, but is not yet a party to the POPs
Protocol.
The 1998 Rotterdam Convention on the Prior Informed Consent (PIC) Procedure for Certain
Hazardous Chemicals and Pesticides in International Trade (http://www.pic.int/
home.php?type=t&id = 5&sid = 16) was developed with strong U.S. support to promote
information exchange and informed risk-based
decisions in the trade of hazardous chemicals
and pesticides. Among other provisions, the
Convention gives force to importing country
decisions on listed chemicals by prohibiting
unwanted exports and requiring that exports
meet conditions specified by importing
governments. Legislative changes to the Toxic
Substances Control Act (TSCA) and the Federal
Insecticide, Fungicide and Rodenticide Act
(FIFRA) that would provide the authority needed
to implement the respective agreements have
been considered in Congress.
Accomplishments
•	At the August 2007 SPP Leaders' Summit
(http://www.spp.gov/), the United States
SMOC Working Group
The SMOC Working Group held a public
meeting in March 2008
(http://www.cec.org/calendar/
details/index. cfm?varlan=english&ID=2085)
to discuss North American cooperative
efforts on assessment and management of
chemicals, including efforts to:
•	Establish a foundation for chemicals
management across North America
•	Develop and implement a sustainable
regional approach to monitoring,
including biomonitoring
•	Reduce the risk from chemicals of
mutual concern in North America, as
identified by the SMOC Working Group
•	Improve environmental performance of
sectors
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committed to completing by 2012 risk characterizations and taking action, as
appropriate, on high- and moderate-production volume chemicals produced above
25,000 pounds per year. EPA created the Chemical Assessment and Management
Program (ChAMP) to implement these commitments.
•	The Commission for Environmental Cooperation (CEC) (http://www.cec.org/home/
index.cfm?varlan=english) directed the Sound Management of Chemicals (SMOC)
Working Group to create a strategy for chemicals management in North America that
addresses issues of mutual concern, supports CEC's priorities, and advances shared
international objectives, including implementing SAICM in the North American region.
In 2007, the SMOC Working Group took initial steps to implement this strategy,
which included:
o A multi-sector and stakeholder workshop to advance the development of a
chemical inventory in Mexico.
o Support for a project to reduce use of mercury in the health care sector and
to update an inventory of mercury use and demand, including mercury-
containing products.
•	The eChemPortal (http://www.oecd.org/ehs/eChemPortal) was released to the public
in June 2007 by the OECD in collaboration with several OECD countries and global
organizations, including the United States, with OPPT taking the lead in the United
States. This information portal is a significant step towards achieving long-standing
international commitments to improve the public availability of data on chemicals. It
is an Internet gateway that provides public access to information on the properties,
hazards and risks of chemicals free of charge and allows users simultaneously to
search multiple databases prepared for government chemical review programs
around the world. The U.S. High Production Volume Information System (HPVIS) is a
key component of the health and environmental effects data that will be directly
accessible from this one Web site.
•	In the past year, OECD member countries have approved six test guidelines (on, for
example, a sediment organism and pesticide residues) and have declassified three
guidance documents (on, for example, honey bees and on pesticide residue
methods), to keep OECD test guidelines (http://www.oecd.org/department/
0,3355,en_2649_34377_l_l_l_l_l,00.html) current with scientific developments.
•	OPPT is currently leading or co-leading 16 projects that will result in new and
updated test guidelines and guidance documents. OPPT relies on consensus-based
OECD test guidelines and Good Laboratory Practices to ensure the development of
high-quality, valid test data under its regulatory testing programs. This ensures that
data generated in the United States are also acceptable to other OECD countries
under the Mutual Acceptance of Data (MAD) agreement which combine to save
governments and industry over $85 million annually.
•	EPA participates in and provides technical support to the U.S. delegation at relevant
Stockholm Convention meetings. This included the third meeting of third meeting of
third meeting of the Conference of the Parties (http://www.pops.int/documents/
meetings/cop_3/meetingdocs/report/default.htm), which took place in Dakar,
Senegal, from April 30 to May 4, 2007, as well as the third meeting of the POPs
Review Committee (http://www.pops.int/documents/meetings/poprc/
POPRC3_report.htm), November 19 - 23, 2007, in Geneva, Switzerland.
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•	EPA participates in relevant Rotterdam Convention meetings including the third and
fourth Chemical Review Committee (CRC) meetings, which occurred in March 2007
and 2008 respectively and took place in Rome. EPA also participated in the third
Conference of the Parties.
•	EPA engages in information exchange and, where feasible, technical assistance, on
the above matters. Most recently, EPA contributed to and participated in a February
2008 Workshop on Continuing Polychlorinated biphenyls (PCB) Management in the
Latin American and Caribbean Countries (http://www.chem.unep.ch/pops/
pcb_activities/Panama2008/default.htm) and in a regional SAICM meeting
(http://www.saicm.org/index.php?content=meeting&.mid = 27&def=l&menuid = 19) to
help facilitate chemical management activities. The SAICM regional meeting also
provided an opportunity to follow up on an earlier international PCB Consultation
Meeting (http://www.chem.unep.ch/pops/pcb_activities/webpage.htm) hosted by
UNEP. For more information on EPA's participation in SAICM activities, read the
SAICM section of this report.
Read other sections of this report for additional information on OECD Screening Information
Data Sets (SIDS) program and EPA's international work with mercury.
SAICM
OPPT is taking a regional approach to implement the Strategic Approach to International
Chemicals Management (SAICM) (http://www.chem.unep.ch/saicm/), an international policy
framework to foster the sound management of chemicals through:
•	The Commission on Environmental Cooperation (CEC) Sound Management of
Chemicals (SMOC) Working Group (http://www.cec.org/programs_projects/
pollutants_health/project/index.cfm?projectID=25&varlan=english)
•	EPA's Chemical Assessment and Management Program (ChAMP) to fulfill
commitments under the Security and Prosperity Partnership (SPP)
(http://www.spp.gov/) of North America.
OPPT has been working with other EPA offices and other federal agencies, including the U.S.
Department of State, to help ensure that various issues and sectors are aware of and
contributing to SAICM's objectives. In addition, OPPT, in cooperation with others, has
facilitated efforts toward risk reduction and information sharing.
Accomplishments
•	OPPT helped create a chemicals management strategy to implement SAICM in the
North American region. In 2007, in accordance with this strategy, OPPT participated
in activities organized by the SMOC Working Group, including a workshop to advance
the development of a chemical inventory in Mexico and projects to inventory mercury
and reduce its use.
•	Helping to further implement the goals of SAICM, under SPP (http://www.spp.gov/),
the United States has committed to complete screening-level characterizations and
take action, as needed, on high- and moderate-production volume chemicals,
produced above 25,000 pounds per year. OPPT will fulfill these commitments through
ChAMP; read the ChAMP section of this report for more information.
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•	In May 2007, OPPT co-sponsored, along with SAICM's Asia-Pacific Region, a
workshop in Bangkok, Thailand, on the United Nations Environment Program
mercury products partnership, focusing on development of projects that promote
information exchange and mercury reductions in products. Such projects include:
o	Mercury product inventory development
o	Mercury market studies and risk management plans
o	Mercury reductions in hospitals
o	Other priorities of interest to countries, geographic regions, and stakeholders
•	OPPT co-sponsored a technical workshop in February 2008 on management of
Polychlorinated Biphenyls (PCBs) in Latin America in response to follow-up meetings
to the Stockholm Convention Conference of the Parties.
•	OPPT co-sponsored the Latin America Regional SAICM Meeting in February 2008 on
the region's chemicals management priorities and implementation planning. EPA's
work in Mexico under the SMOC Working Group and SPP complements efforts in the
Americas as Mexico is also a key participant with chemicals management activities in
the Latin America region.
EPA is also providing global leadership on mercury partnerships with UNEP and on
Perfluorooctanic acid (PFOA) through its PFOA Stewardship Program. For more information
on these activities, read the International Work, ChAMP, HPV, PFOA and international work
with mercury sections of this report.
OECD HPV Chemicals Program
The Organization for Economic Cooperation and Development (OECD) High Production
Volume (HPV) Chemicals Program is an international voluntary program in which EPA is an
active participant. Within the program, each participating country's government works with
industry to obtain screening-level toxicity data and other basic information on HPV
chemicals. Each country prepares assessments of these data for presentation at biannual
meetings. In addition to presenting chemical assessments, each meeting provides a forum
for technical discussions.
Under the OECD HPV Chemicals Program, EPA is sponsoring a growing number of HPV
chemicals. While the United States has committed to be responsible for 25 percent of the
chemicals in this program, in practice it has currently handled 45 percent and has
committed to review approximately 500 chemicals between 2005 and 2010. Read the HPV
Challenge section of this report for more information.
Through its participation in the OECD HPV Chemicals Program, the United States benefits
from the review of HPV chemicals by a wide group of international experts. Further, the
United States strengthens relationships with the international community through this
cooperative effort. Publication of the final OECD screening-level assessments offers the
public a concise view of the human health and ecological hazards associated with
international HPV chemicals.
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Accomplishments
•	At the April 2007 Screening Information Data Set (SIDS) Initial Assessment Meeting,
referred to as the SIAM, the United States reviewed and presented assessments for
15 chemicals and reviewed data on an additional 20 chemicals presented by other
countries.
•	At the October 2007 SIAM, the United States reviewed and presented assessments
for 36 chemicals and reviewed data on an additional 70 chemicals presented by other
countries or by the Business and Industry Advisory Committee (BIAC).
•	At the April 2008 SIAM, the United States reviewed and presented assessments for
13 chemicals and reviewed an additional 9 chemicals presented by other countries or
by BIAC.
View published cases on specific chemicals through the United Nations Environment
Program (http://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html) or European
chemical Substances Information System (http://ecb.jrc.it/esis/index.php?PGM = hpv) Web
sites.
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Reducing Risks from Specific Chemicals
OPPT develops regulations and policies designed to reduce
risks to human health and the environment from several
specific priority chemicals, known as National Program
Chemicals. The National Program Chemicals include
chemicals that have specific statutory requirements (e.g.,
lead, asbestos, polychlorinated biphenyls (PCBs)) as well as
other multimedia pollutants of concern (e.g., mercury and
dioxin).
Accomplishments
•	In March 2008 OPPT finalized, a rule (http://www.epa.gov/lead/pubs/
renovation.htm) requiring persons engaged in renovation, repair and painting
activities in pre-1978 housing and child-occupied facilities to be trained and to use
lead-safe work practices for activities that disturb lead-based paint
(http://www.epa.gov/lead/).
•	EPA awarded more than $9.2 million in grant dollars for national, tribal and local lead
poisoning prevention projects to address populations at risk for elevated blood-lead
levels through three grant programs (http://www.epa.gov/lead/pubs/grantmap.htm)
in 2007.
•	On April 2, 2007, EPA published the brochure, Current Best Practices for Preventing
Asbestos Exposure Among Brake and Clutch Repair Workers (http://www.epa.gov/
asbestos/pubs/brakesbrochure.html), giving automotive professionals and home
mechanics information on preventing exposure to brake and clutch dust that may
contain asbestos fibers.
•	Effective October 9, 2007, EPA transferred management (http://www.epa.gov/pcb/
transfer.htm) of most of the PCB cleanup and disposal program from OPPTS to the
Office of Solid Waste and Emergency Response; however, OPPTS will continue to
administer the "use" portion of the PCB program.
•	In 2007, EPA hosted commodity-grade mercury stakeholder panel
(http://www.epa.gov/mercury/stocks/index.htm) meetings to discuss options for
managing non-federal supplies of mercury in the United States.
•	Working with the states (http://www.epa.gov/epawaste/hazard/tsd/mercury/
live.htm), EPA promoted recycling, collection, and reduction of mercury-containing
products such as mercury thermostats, industrial non-fever thermometers and
fluorescent lamps.
•	On October 5, 2007, EPA issued a final Significant New Use Rule
(http://www.epa.gov/mercury/snur.htm) on mercury auto and convenience
• EPA continued in 2007 to participate in the United Nations Environment Program
(UNEP) Mercury Products Partnership to reduce mercury in products internationally
by helping to build capacity for countries to take further action on mercury use in
products.
switches.
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Read more about EPA's lead (http://www.epa.gov/lead/), asbestos
(http://www.epa.gov/asbestos/), PCBs (http://www.epa.gov/pcbs/), and mercury
(http://www.epa.gov/mercury/) programs.
Lead Poisoning Prevention
Lead (http://www.epa.gov/lead/) is a highly toxic metal that
was used for many years in products found in and around our
homes. Lead may cause a range of health effects, from
behavioral problems and learning disabilities to seizures and
death. Children under six years of age are most at risk.
Research suggests that the primary sources of lead exposure
for most children are deteriorating lead-based paint, lead-
contaminated dust, and lead-contaminated residential soil.
EPA has played a major role in addressing these residential
lead hazards. EPA has largely completed the regulatory
framework assigned to it by Congress in Title X of the
Residential Lead-Based Paint Hazard Reduction Act of 1992
by:
• Issuing rules creating a training and certification
program for individuals and firms engaged in lead-
based paint activities;
•	Establishing hazard standards for lead in paint, dust,
and soil; and
•	Requiring pre-renovation education and lead hazard disclosure in target housing.
In order to meet the 2010 federal government goal of eliminating childhood lead poisoning
as a major public health concern, EPA is focusing funding resources on the most vulnerable
populations in state, localities and tribal areas—those that have rates of lead poisoning
above the national average and those in areas where sufficient screening has not yet
occurred to determine rates of lead poisoning. EPA has addressed populations still at risk for
elevated blood-lead levels through three competitive grant programs. The grants are
available to a wide range of applicants, including state and local governments, federally-
recognized Indian tribes and tribal consortia, territories, institutions of higher learning, and
nonprofit organizations.
Accomplishments
•	In another step to achieve the 2010 goal, in March 2008 OPPT finalized its Lead
Renovation, Repair, and Painting rule (http://www.epa.gov/lead/pubs/
renovation.htm) requiring persons engaged in renovation, repair, and painting
activities in pre-1978 housing and child-occupied facilities to be trained and certified
and to use lead-safe work practices for activities that disturb lead-based paint
(http://www.epa.gov/lead/). The purpose of the rule is to reduce potential exposure
to dangerous levels of lead resulting from lead-based paint in older housing. OPPT
also released several outreach documents relating to the rule, including:
o Renovate Right: Important Lead Hazard Information for Families, Child Care
Providers, and Schools (http://www.epa.gov/oppt/lead/pubs/
Strategic Plan
Goal Four of EPA's Strategic
Plan includes a goal to
eliminate childhood lead
poisoning in the United States
as a major public health
concern by the year 2010.
As a result of EPA's lead
poisoning prevention programs
and other efforts across the
federal government, children's
elevated blood-lead levels in
the United States have
declined dramatically. In 1978,
3-4 million children had
elevated blood-lead levels. By
2002, that number had
dropped to 310,000 and it
continues to decline.
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renovaterightbrochure.pdf; en Espanol: http://www.epa.gov/oppt/lead/pubs/
renovaterightbrochuresp.pdf)
o Contractors: Lead Safety During Renovation (PDF)
(http://www.epa.gov/oppt/lead/pubs/contractor_brochure.pdf; HTML version:
http://www.epa.gov/oppt/lead/pubs/contractor_brochure.htm; en Espanol:
http://www.epa.gov/oppt/lead/pubs/contractor_brochuresp.pdf)
o EPA Small Entity Compliance Guide to Renovate Right
(http://www.epa.gov/oppt/lead/pubs/sbcomplianceguide.pdf)
Read additional information on the rule for lead-safe work requirements:
http://www.epa.gov/lead/pubs/renovation.htm.
•	On August 21, 2008, EPA issued a proposed rule (http://www.epa.gov/fedrgstr/
EPA-TOX/2008/August/Day-21/tl9432.htm) to modify and lower the existing fees for
various EPA accredidations and certifications under the Agency's Lead-based Paint
Activities regulations. The proposed rule would establish fees charged for training
programs seeking accreditation, for firms engaged in renovations seeking
certification, and for individuals (for example, risk assessors) or firms engaged in
lead-based paint activities seeking certification. The proposed rule would apply only
in those states and tribes without their own authorized lead programs. The proposed
rule would also establish fees for the new Lead Renovation, Repair and Painting rule
(http://www.epa.g0v/lead/pubs/renovation.htm#fee). The fees are required under
section 402 of the Toxic Substances Control Act (TSCA) to recover the cost of
administering and enforcing the law's requirements. Read EPA's fact sheet on the
proposed rule: http://www.epa.gov/lead/pubs/faqfee.htm.
•	In 2007 and 2008, EPA awarded approximately 96 grants as part of three
competitive grant programs aimed at promoting efforts to prevent or reduce
childhood lead poisoning.
In 2007, EPA awarded more than $5.2 million in targeted grants
(http://www.epa.g0v/lead/pubs/grantmap.htm#targeted) to 49 projects in areas
with high incidences of children with elevated blood-lead levels in vulnerable
populations.
In 2007 and 2008, EPA awarded more than $5.1 million in national community-based
grants (http://www.epa.g0v/lead/pubs/grantmap.htm#national) to 23 projects to
reduce the incidence of childhood lead poisoning in communities with older housing
and to support community activities such as outreach, training, and local ordinance
development projects.
In 2007 and 2008, EPA awarded nearly $1.5 million in Tribal lead grants
(http://www.epa.g0v/lead/pubs/grantmap.htm#tribal) to 23 tribal projects to reduce
the incidence of childhood lead poisoning in tribal communities and will fund
educational outreach and baseline assessments of Tribal children's lead exposure.
•	EPA and the Sierra Club reached a settlement on a lawsuit that came after EPA
denied a petition filed by the Sierra Club under Section 21 of the Toxic Substances
Control Act (TSCA). In this petition, the Sierra Club expressed concerns about risks
to children from products containing lead, such as toy jewelry (http://www.epa.gov/
oppt/lead/pubs/toyjewelry.htm), and requested that EPA take certain actions to
address these risks. Under TSCA Section 21 (http://www.epa.gov/oppt/chemtest/
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pubs/sect21.html), any person may petition EPA to issue, amend, or repeal a rule
under other sections of TSCA. On April 30, 2007, fulfilling actions agreed to in the
lawsuit settlement (http://www.epa.gov/lead/pubs/finalsettlement.pdf) with the
Sierra Club regarding lead in children's products, EPA sent:
o A letter to the U.S. Consumer Product Safety Commission (CPSC)
(http://www.epa.gov/lead/pubs/cpscletter.pdf) describing its continuing
concerns about the presence of lead in children's products
o Letters to 120 companies (http://www.epa.gov/lead/pubs/jewelryletter.pdf)
alerting them to reporting requirements under TSCA section 8(e)
(http://www.epa.gov/oppt/tsca8e/pubs/rguide03.htm).
Under the settlement, EPA also agreed to conduct a rulemaking to obtain existing
health and safety studies on lead in children's products. The rule
(http://www.epa.g0v/lead/pubs/t0yjewelry.htm#jewelry) was issued January 29,
2008.
•	EPA joined the CPSC in publicizing recalls of toys containing lead to alert parents.
Read more information about EPA's lead poisoning prevention programs:
http://www.epa.gov/lead.
Asbestos
Asbestos (http://www.epa.gov/asbestos/) is the common name for a group of naturally
occurring mineral fibers with high tensile strength, the ability to be woven, and resistance to
heat and most chemicals. Because of these properties, asbestos fibers have been used in a
wide range of manufactured goods, including construction materials and friction products
such as automobile clutches and brakes.
Exposure to asbestos can be harmful to human health if fibers are released into the air
when asbestos is disturbed or in poor condition. These fibers can cause serious health
problems when inhaled into the lungs. Asbestos exposure has been associated with a
number of serious health problems and diseases, including asbestosis, lung cancer, and
mesothelioma. EPA is committed to providing the public with accurate and timely public
health information and is continuing to address concerns about asbestos.
The Asbestos Model Accreditation Plan (MAP) provides training requirements
(http://www.epa.gov/asbestos/pubs/training.html) for states to follow when developing
their own state programs for training asbestos professionals. The asbestos MAP requires
initial training (which includes hands-on training) and annual refresher training for the
various course disciplines.
Accomplishments
•	On April 2, 2007, EPA released a new brochure that provides health and safety
information for professional and do-it-yourself mechanics who may work with
asbestos-containing automotive components. Current Best Practices for Preventing
Asbestos Exposure Among Brake and Clutch Repair Workers (http://www.epa.gov/
asbestos/pubs/brakesbrochure.html) emphasizes the need to prevent asbestos fibers
from escaping into the air during repair work. While it is impossible to tell if clutch
and brake components contain asbestos, the brochure advises that mechanics should
automatically assume the possible presence of asbestos.
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The brochure:
o Emphasizes ways to avoid asbestos exposure, such as warning against
blowing dust from brakes and clutches with compressed air,
o Summarizes work practices by detailing three recognized methods for
containing asbestos dust in a professional automotive shop, and
o Lists do's and don'ts for do-it-yourself mechanics (e.g., not taking work-
clothing inside the house to prevent exposing family members to asbestos
dust).
• EPA responded to a public inquiry stating that the MAP does not prohibit online
annual refresher training and that states may approve such training courses at their
discretion. On July 9, 2007, EPA provided states with guidelines for evaluating online
MAP annual refresher training (http://www.epa.gov/asbestos/pubs/training.html)
courses.
View EPA's Asbestos Web site (http://www.epa.gov/oppt/asbestos/) for more information
about specific asbestos issues. EPA has a toll-free hotline for asbestos issues (1-800-471-
7127).
PCBs
Polychlorinated biphenyls (PCBs) (http://www.epa.gov/pcb/) are mixtures of synthetic
organic chemicals with the same basic chemical structure and similar physical properties
ranging from oily liquids to waxy solids. Due to their non-flammability, chemical stability,
high boiling point and electrical insulating properties, PCBs were used in hundreds of
industrial and commercial applications including electrical, heat transfer, and hydraulic
equipment; as plasticizers in paints, plastics and rubber products; in pigments, dyes and
carbonless copy paper and many other applications. More than 1.5 billion pounds of PCBs
were manufactured in the United States prior to cessation of production in 1977.
PCBs have been demonstrated to cause a variety of adverse health effects, including cancer
in animals, and a number of serious non-cancer health effects in animals, including effects
on the immune system, reproductive system, nervous system, endocrine system and other
health effects.
PCBs were specifically regulated by the Toxic Substances Control Act (TSCA) when the law
passed in 1976 because Congress believed that the chemical and toxicological properties of
PCBs posed unacceptable risks to public health and the environment. TSCA §6(e)
specifically directs EPA to regulate the manufacturing, processing, distribution in commerce,
use, and disposal of PCBs.
The law generally prohibits the use of PCBs except in a totally controlled manner; it allows
EPA to authorize uses of PCBs provided that they do not present an unreasonable risk.
More than a dozen major and minor rules (http://www.epa.gov/epaoswer/hazwaste/
pcbs/pubs/laws.htm) have been promulgated since 1978 to implement the bans, provide
authorizations for use, and control the disposal of PCBs. EPA efforts regarding PCBs focus on
the reduction and elimination of their use and encouraging their cleanup and safe disposal.
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Accomplishments
•	In March 2007, the Aberdeen Chemical Agent Disposal Facility (ABCDF) became the
first chemical weapons facility in the continental United States to completely dispose
of its stockpile and to decontaminate and demolish its disposal plant. ABDCF
neutralized 1,623 tons of mustard agents.
•	On July 6, 2007, EPA renewed the National PCB Disposal Approval for the U.S. Army
Chemical Agent M55 rocket incinerators (http://www.epa.gov/pcbs/pubs/
army-inc.htm) at Pine Bluff, Ark., and Umatilla, Ore. The approval, which allows the
Army to continue to burn stockpiled chemical agent rockets containing PCBs for five
years, will terminate on July 6, 2012.
•	On September 18, 2007, EPA published a final rule, Polychlorinated Biphenyls:
Manufacturing (Import) Exemptions (http://www.epa.gov/fedrgstr/
EPA-TOX/2007/September/Day-18/tl8345.htm), granting a petition submitted to
EPA by the Defense Logistics Agency (DLA) to import 1.3 million pounds of PCBs and
PCB items currently in temporary storage at U.S. military installations in Japan for
environmentally sound disposal in the United States.
•	To improve program and administrative efficiency, EPA transferred the management
of the PCB cleanup and disposal program (http://www.epa.gov/epaoswer/hazwaste/
pcbs/transfer.htm) to the Office of Solid Waste and Emergency Response from
OPPTS. The change was effective October 1, 2007. OPPTS will continue to administer
the "use" portion of the PCB program.
Read more information on PCBs (http://www.epa.gov/pcb/) and information and guidance
on PCBs and ship scrapping (http://www.epa.gov/Compliance/resources/publications/
civil/federal/shipscra pguide.pdf).
Reducing Risks from Mercury
Mercury is contained in some of the products we use and in some of the fish we eat. It can
be found in your home, in health-care facilities and in schools. EPA's long-term goal is to
reduce risks associated with mercury. Almost all people have at least trace amounts of
mercury in their tissues. Mercury can affect the nervous system. People are mainly exposed
to methylmercury, an organic compound, when they eat fish and shellfish that contain
methylmercury. Still developing, fetuses, infants and children are particularly sensitive to
the effects of methylmercury on the nervous system.
The primary pathway of human exposure to mercury is through eating fish containing
methylmercury. Fish and shellfish are an important part of a healthy diet. Research shows
that most people's fish consumption does not cause a health concern. Fish that are higher in
the food chain have much higher methylmercury concentrations than fish that are lower in
the food chain. Individuals may also become exposed to harmful levels of elemental
mercury vapor found indoors in work places and homes. When exposed to air, elemental
mercury vaporizes and can be inhaled. The number of individuals exposed in the United
States in this way is very small.
Because mercury is a problem that knows no geographic boundaries, EPA's work has an
international component. Mercury can travel thousands of miles in the atmosphere before it
is eventually deposited back to the Earth in rainfall or in dry gaseous forms (see Mercury
Emissions: The Global Context: http://www.epa.gov/mercury/control_emissions/
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global.htm). Current estimates are that less than half of all mercury deposition within the
United States comes from U.S. sources (see Mercury: Basic Information:
http://www.epa.gov/mercury/about.htm).
OPPT led the development of EPA's Roadmap for Mercury (http://www.epa.gov/mercury/
roadmap.htm) published in July 2006. The Roadmap describes the Agency's progress to
date in dealing with mercury issues domestically and internationally, and outlines EPA's
major ongoing and planned actions to address risks associated with mercury.
Accomplishments
•	EPA continued to implement key commitments in the Roadmap for Mercury
(http://www.epa.gov/mercury/roadmap.htm). In 2007, OPPT focused on reducing
mercury in domestic products and promoting stakeholders' understanding of the
impacts associated with long-term management of excess commodity-grade
mercury.
•	OPPT, with several other federal partners, hosted four stakeholder-panel meetings
(http://www.epa.gov/mercury/stocks/index.htm) with technical experts and
interested parties to assess options for managing non-federal stocks of commodity-
grade elemental mercury. Held between May and September 2007, 14 stakeholders
were panel members at these public meetings, representing a balanced mix of
industry, academia, non-governmental organizations, and states. An interagency
workgroup assessed the input received during the stakeholder process and is
initiating a separate interagency process to analyze and better understand the issues
associated with a ban on the export of mercury from the United States.
•	On October 5, 2007, OPPT issued a final Significant New Use Rule (SNUR)
(http://www.epa.gov/mercury/snur.htm) to address the use of new mercury
switches in motor vehicles. Automakers voluntarily discontinued use of certain
mercury switches in vehicles in 2003. The SNUR will give EPA the opportunity to
evaluate the potential risks of resuming the use of elemental mercury in the
switches, and, if necessary, to prohibit or limit their use to prevent unreasonable risk
to human health or the environment.
•	OPPT began working with states to promote recycling, collection, and reduction of
mercury-containing products such as mercury thermostats and non-fever
thermometers.
•	OPPT has provided continued leadership and resources to support the United Nations
Environment Program (UNEP) Partnerships aimed at addressing risks associated with
mercury uses, releases and exposure. Current partnerships include pilot projects in
five key sectors:
o	Chlor-alkali facilities
o	Fate and transport research
o	Artisanal and small-scale gold mining
o	Coal combustion
o	Mercury products
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OPPT attended the 24th session of the UNEP Governing Council in February 2007, at
which UNEP encouraged continued action and support for implementing the Global
Partnerships for Mercury (http://www.chem.unep.ch/mercury/partnerships/), among
other steps.
•	As the lead of the Mercury Reductions Products Partnership, OPPT made substantial
progress in 2007 by developing formal partnerships with other countries to reduce
mercury in products. This partnership seeks to transfer best practices related to
reducing releases from the manufacture, use, and disposal of mercury-containing
products by identifying effective substitutes.
The partnership has increased in number to include:
o Mexico, China, Costa Rica, and Argentina, which are reducing mercury in
hospitals.
o Burkina Faso, South Africa, Chile, Ecuador, Panama and Mexico, which are
conducting mercury product inventories, market studies and mercury risk
management projects.
•	OPPT co-hosted "Mercury In Our World: Conference on Mercury and Other Hazardous
Chemicals in Southeast Asia Schools," in Bangkok, Thailand, April 22-24, 2008.
Other conference sponsors were Thailand's Pollution Control Department, UNEP, and
Merck Thailand. The conference was designed to be a train-the-trainer session for
university and high school students, teachers, and school administrators, enabling
them to return to their countries and schools and share what they had learned about
safe management and disposal of mercury and other hazardous chemicals.
Instruction manuals aimed at teachers/administrators and students were developed
and shared at the conference, emphasizing the importance of:
o Mercury and chemical management,
o Identification of hazardous chemicals and equipment in schools, and
o Policies and actions for school administrators and teachers.
The student manuals also contained information for student projects and activities
designed to solidify their understanding of international chemical symbols, where
hazardous chemicals are typically found in schools, identifying specific hazards,
scenario role playing, and student projects using various media to present the
message.
Read more information on OPPT's work on a mercury-related partnership: Partnership for
Sustainable Healthcare (PSH) (http://www.epa.gov/p2/pubs/psh.htm).
View EPA's Mercury Web page: http://www.epa.gov/mercury/.
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Working to Prevent Pollution
The Pollution Prevention Act
of 1990 established that
prevention, or "source
reduction," is the Agency's
first priority for addressing
pollution and waste.
Therefore, EPA's guiding
	 principle is to reduce when
possible potential sources of waste and pollution rather than
controlling pollution or treating or recycling waste after it is
created.
The Office of Pollution Prevention and Toxics (OPPT) has
been complementing traditional "command and control"
approaches with innovative, collaborative programs that
encourage environmental stewardship
(http://www.epa.gov/p2/) as both a critical environmental
strategy and a sustainable business practice. For example,
OPPT has been using pollution prevention (P2) approaches to
encourage replacement of existing chemicals of concern in
the marketplace. OPPT offers incentives to create innovative technologies and substitute
safer chemicals for riskier ones through programs such as Green Chemistry
(http://www.epa.gov/greenchemistry), Design for the Environment
(http://www.epa.gov/dfe), Sustainable Futures (http://www.epa.gov/oppt/sf), and the High
Production Volume Challenge (http://www.epa.gov/hpv), to name a few. OPPT also is
working to integrate pollution prevention into its traditional "command and control"
regulatory activities across air, water and waste regulations.
The Environmental Assistance Network was created to coordinate activities within EPA's
Strategic Goal 5, Environmental Stewardship. Among EPA's five major strategic goals
(http://www.epa.gov/cfo/plan/plan.htm), EPA's environmental stewardship goal includes
OPPT's cross-cutting coordination on P2 opportunities in enforcement and compliance, small
business development, and P2 research and development.
Accomplishments
•	The Presidential Green Chemistry Challenge Awards Program celebrated its 13th year
at the June 2008 awards ceremony. To date the Program has given out 67 awards -
14 awards to academic researchers, 13 awards to small businesses, and 40 awards
to larger businesses and organizations.
•	Design for the Environment's (DfE) Formulator Safer Product Recognition Program
(http://www.epa.gov/dfe/pubs/projects/formulat/index.htm), as of June 2008, had
approximately 80 stakeholder partners and had allowed use of DfE's label
(http://www.epa.gov/dfe/pubs/projects/formulat/label.htm) on approximately 500
safer products, distinguishing them as having been reformulated to be
environmentally safer as well as cost competitive and effective.
•	Sustainable Futures (http://www.epa.gov/oppt/sf/) and the PBT Profiler
(http://www.epa.gov/oppt/sf/tools/pbtprofiler.htm) provide online software enabling
chemical manufacturing companies to assess and identify safer and greener
Strategic Plan
A target in Goal Five of EPA's
Strategic Plan is to reduce
pollution by 4.5 billion pounds,
conserve 31.5 trillion BTUs of
energy and 19 billion gallons
of water, and save $791.9
million by 2011.
OPPT's pollution prevention
program received an 82.7
percent rating from the Office
of Management and Budget on
its Program Assessment
Rating Tool (PART)
effectiveness review, the third
highest rating to date at the
time it was assessed. In 2007,
OPPT continued to implement
the recommendations from its
PART assessment.
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chemicals early in their design phase. Approximately 11 percent of 2007 through
June 2008 New Chemical pre-manufacture notifications were independently
evaluated by submitters at the research and development stage using the
Sustainable Futures tools.
•	EPA's Green Building Workgroup, a cross-Agency group co-led by OPPT, guides EPA's
development of green building policies, programs, partnerships, communications,
and operations. Administrator Steve Johnson announced April 21, 2008, that EPA will
be emphasizing green building as a new strategic direction. As a key partner in this
strategy, OPPT committed to leading the Agency's engagement in developing green
building consensus standards, including the U.S. Green Building Council's LEED
Rating System and ASTM International's sustainable building standards.
In addition, OPPT further contributed to green building in 2007 through the
development and expansion of the tool, Federal Green Construction Guide for
Specifiers (http://www.epa.g0v/epp/t00ls/index.htm#b), which was a winner of the
"Beyond Green 2007 High Performance Building Awards" (http://www.wbdg.org/
news/release_011608.php) from the Sustainable Building Industry Council.
•	OPPT supported the Pollution Prevention Resource Exchange (P2Rx) by awarding
approximately $800,000 in grants to eight regional pollution prevention information
centers, which provide pollution prevention information, networking opportunities
and other services to states, local governments and technical assistance providers in
their regions.
•	EPA's Partnership for Sustainable Healthcare (PSH) evolved from a previous Agency
partnership program to a fully independent entity, retaining the partnership
program's name Hospitals for a Healthy Environment (H2E) (http://www.h2e-
online.org/). The new H2E, a 501(c)(3) non-profit organization, is a sub-recipient of
an EPA cooperative agreement with the National Center for Manufacturing Sciences
(NCMS).
EPA provides technical assistance to help NCMS and the new H2E carry out the
cooperative agreement in which H2E provides hands-on help and information to
hospitals, in particular, to reduce mercury and other wastes, and sponsors an awards
program to recognize health-care facilities as good environmental stewards.
Through the efforts of PSH, NCMS, and H2E, in 2007 through June 2008 the
healthcare sector:
o	Eliminated over 986,500 grams of mercury;
o	Recycled over 1,811,900 tons of waste;
o	Reduced nearly 373,800 tons of hazardous waste;
o	Conserved 70 million gallons of water; and
o	Saved more than $28.2 million.
Read more information on EPA's Partnership for Sustainable Healthcare (PSH)
(http://www.epa.gov/p2/pubs/psh.htm).
•	OPPT helped create and now co-chairs the EPA Office Directors' Multimedia and
Pollution Prevention Forum (M2P2). This is the principal venue within the Agency for
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reviewing and exchanging information among media programs on activities to
promote a multi-media approach to pollution prevention (e.g., rules with significant
cross-media impacts, identification of regulatory/voluntary synergies, etc.).
Green Suppliers Network
The Green Suppliers Network is an OPPT program helping companies that comprise the
supply chain of large manufacturers to save money while reducing pollution and preserving
resources. By providing technical assistance in lean manufacturing and pollution prevention
techniques, the Green Suppliers Network improves suppliers' productivity, efficiency, and
environmental performance.
The Green Suppliers Network is a collaborative venture among industry, EPA, and the U.S.
Department of Commerce's Manufacturing Extension Partnership (MEP). The Green
Suppliers Network works with all levels of the manufacturing supply chain to improve
processes and minimize waste generation. Through onsite technical reviews, suppliers
continuously learn ways to increase energy efficiency, identify cost-saving opportunities,
and optimize resources and technologies to eliminate waste. The result has been more
effective processes and products with higher profits and fewer environmental impacts.
The program worked with the Lean and Environment Initiative in EPA's Office of Policy,
Economics and Innovation to create a toolkit for companies that helps them reduce costs
while reducing waste and resource use.
The Green Suppliers Network is available to any manufacturing sector. Currently, the
aerospace, automotive, healthcare/pharmaceutical, office furniture and utility industries are
leading the way and benefiting from the Green Suppliers Network.
Accomplishments
•	Identified more than $9 million in potential, annual cost-saving opportunities,
including $4 million from potential reduced environmental impacts, during 26
technical reviews conducted by Green Suppliers Network from January 2007 through
June 2008. Also identified were opportunities to:
o Conserve 30.1 million kWh of energy (102K MM Btu) and more than 24.9
million gallons of water
o Reduce more than 2.4 million pounds of solid waste, more than 111,000
pounds of hazardous waste, and the use of over 177,000 pounds of toxic and
hazardous chemicals
•	The Green Suppliers Network conducted training sessions
(http://www.greensuppliers.gov/gsn/page.gsn?id = highlights#training) for technical
assistance providers at four conferences from January 2007 through June 2008 to
share best practices and innovative approaches in lean manufacturing and pollution
prevention.
•	The program collaborated with EPA's Performance Track (http://www.epa.gov/
perftrac/) program in 2007 to review a Johnson & Johnson supplier, and the
company is currently scheduling two additional reviews. Performance Track has
announced that it plans to reduce the cost of reviews for its members by $2,000, and
has funding in place to reduce costs for nine reviews.
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o American Electric Power became the first utility company to join the Green
Suppliers Network, and is paying for five of their suppliers to undergo reviews
through Performance Track.
o Pacific Gas & Electric Co. has also joined the program and will fund a review.
•	The Green Suppliers Network developed an environmental benefits calculator
(http://www.greensuppliers.gov/gsn/page.gsn?id = program_materials#calc) in 2007
for stakeholders to quantify environmental results and future environmental savings.
•	Through the Commission for Environmental Cooperation (http://www.cec.org/
home/index.cfm?varlan=english), the Green Suppliers Network began work in 2007
to build a similar network in Mexico after the successful collaboration with
Environment Canada to help them adopt the Green Suppliers Network model for its
"Green Business Network."
•	The collaborative effort between Goodwill Industries International, Inc. and the
Green Suppliers Network Automotive Sector (Suppliers Partnership for the
Environment) has resulted, through 2007, in:
o	1.06 million pounds of plastic remanufactured
o	30,000 pounds of corrugated cardboard recycled per month
o	2,336 vehicle batteries recharged/reused
o	230,000 vehicle parts repackaged
o	over 2 million pounds of electronic waste diverted from landfills
o	60 jobs created for the disadvantaged and disabled
•	Based on an agreement made in 2007, the tools (http://www.greensuppliers.gov/
gsn/page.gsn?id=tools) of the Green Suppliers Network program will be offered to
members of the Business and Institutional Furniture Manufacturer's Association as a
resource to help meet their new sustainability standards.
•	In 2007, the Green Suppliers Network incorporated environmental metrics questions
into the quarterly survey conducted by the Department of Commerce's
Manufacturing Extension Partnership (MEP) to further quantify results
(http://www.greensuppliers.gov/gsn/page.gsn?id = measureresults) from Green
Suppliers Network reviews (http://www.greensuppliers.gov/gsn/
page.gsn?id=technicalreviews).
Read more information on the Green Suppliers Network: http://www.greensuppliers.gov/.
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Design for the Environment
OPPT's Design for the Environment (DfE) program focuses on
collaborating with industries that possess the potential for
chemical risk reduction and a strong motivation to make
lasting changes. DfE convenes representatives from those
industries and environmental groups in partnership programs
that evaluate alternative technologies, materials and process
improvements based on human health and environmental
considerations, as well as performance and cost.
As incentives for participation and driving change, DfE offers
unique technical tools, methodologies, and expertise. EPA
also allows safer products to carry the Design for the
Environment (DfE) label. This mark allows consumers to
quickly identify and choose products that are safer for families and can help protect the
environment.
Having the DfE label on a product means that an EPA scientific review team has screened
each ingredient for potential human health and environmental effects and that—based on
currently available information, EPA predictive models, and expert judgment—the product
contains only those ingredients that pose the least concern among chemicals in their class.
The DfE program has allowed use of their label on hundreds of products.
The DfE Program has reached more than 200,000 business facilities and approximately 2
million workers and is reducing the use of chemicals of concern by approximately 180
million pounds per year.
Accomplishments
•	On April 21, 2007, the Institute of Scrap Recycling Industries, Inc. awarded EPA's
Design for the Environment (DfE) Program (http://www.epa.gov/dfe/) its 2007
Design for Recycling Award. The DfE program was chosen for its overall leadership in
creating innovative design partnerships and its dedication to empowering businesses
and industry sectors to incorporate environmental considerations into decision-
making processes.
•	DfE's Formulator Safer Product Recognition Program (http://www.epa.gov/dfe/pubs/
projects/formulat/index.htm), which by June 2008 had about 80 stakeholder
partners and allowed use of DfE's label on approximately 500 safer products,
distinguishes products that have been reformulated to be environmentally safer, cost
competitive and effective.
By providing chemical and toxicological information and suggesting safer substitutes,
the Formulator Program reduced the use of an estimated 240 million pounds of
chemicals of concern from January 2007 through June 2008. Formulator Partnerships
have become respected and sought-after in the industrial and institutional cleaning
sector. The DfE program is now working to create partnerships in the consumer
cleaning products sector. Read more information about partners and recognized
products (http://www.epa.gov/dfe/pubs/projects/formulat/formpart.htm) authorized
to use the DfE label (http://www.epa.gov/dfe/pubs/projects/formulat/label.htm).
Safer Products
Look for the DfE Label!
O"-'.
U.S. EPA
http://www.eDa.aov/dfe/Dubs/
proiects/formulat/label.htm
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•	DfE created the voluntary Safer Detergents Stewardship Initiative (SDSI)
(http://www.epa.gov/dfe/pubs/projects/formulat/sdsi.htm) to promote the use of
safer surfactants in cleaning and other products. Safer surfactants are those that
degrade quickly into non-toxic products. DfE has worked with outside parties to
develop a database of safer cleaning product ingredients called CleanGredients
(http://cleangredients.org/) that serves as a marketplace for the product formulation
industry. As of 2007, a total of 12 chemical manufacturers have paid to list 87
cleaning-product chemicals in the system, and more than 200 formulators have paid
to use the system. EPA held the SDSI Recognition Ceremony on November 19, 2008,
and recognized 40 Champions and 21 Partners.
•	The DfE Wire and Cable Partnership (http://www.epa.gov/dfe/pubs/projects/
wire-cable/index.htm) was formed in 2007 to evaluate the impacts of standard and
alternative wire and cable formulations. The wire and cable partnership is using a
life-cycle assessment approach to assess heat stabilizers, flame retardants, and
polymer systems used in wire and cable insulation and jacketing. A study by the DfE
Toxics Use Reduction Institute Wire & Cable Partnership will help companies make
environmentally sound product and material choices and reduce overall
environmental and health impacts of the products. DfE will complete a partnership
report in 2008.
•	The DfE Nail Salons Project (http://www.epa.gov/dfe/pubs/projects/salon/index.htm)
was formed to collect and provide information on personal protective equipment and
management practices that can reduce or minimize risks associated with chemical
exposures in nail care activities. In March 2007, DfE published online the revised
best practices guide, Protecting the Health of Nail Salon Workers
(http://www.epa.gov/dfe/pubs/projects/salon/nailsalonguide.pdf). This guide is
designed to educate nail salon owners and employees of potential chemical hazards
and to recommend best practices to minimize health and environmental risks in their
shops. Translations of this guide in Vietnamese and Korean were also made available
online.
Read more information on the DfE Program (http://www.epa.gov/dfe/) and its partnership
projects (http://www.epa.gov/dfe/pubs/projects/index.htm), and other sections of this
report for information on DfE's collaboration with the Community Action for a Renewed
Environment (CARE) Program and its work through the Resources Conservation Challenge.
Green Chemistry
OPPT's Green Chemistry Program works with the chemical community to promote the
environmentally conscious design of chemical products and processes that are safer to
human health and the environment. The Program's flagship activity, the annual Presidential
Green Chemistry Challenge Awards, encourages and recognizes the significant scientific,
economic, human health, and environmental benefits that green chemistry technologies
offer.
The Presidential Green Chemistry Challenge Awards Program celebrated its 13th year at the
June 2008 awards ceremony. To date the Program has given out 67 awards—14 awards to
academic researchers, 13 awards to small businesses, and 40 awards to larger businesses
and organizations.
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Accomplishments
•	Together, all Green Chemistry award-winning technologies have resulted in:
o 193 million pounds of hazardous chemicals and solvents eliminated each
year—enough to fill 890 railroad tank cars or a train 11 miles long;
o 21 billion gallons of water saved each year—the amount used by 820,000
people annually; and
o 57 million pounds of carbon dioxide releases to air eliminated each year-
equal to taking 6,000 automobiles off the road.
•	More than 1,000 innovative technologies have been nominated for the Green
Chemistry awards. The total benefits from all of these technologies include:
o 1.2 billion pounds per year of hazardous chemicals eliminated;
o 21 billion gallons of water per year saved (this includes both water used and
waste water eliminated);
o 81 million pounds of carbon dioxide emissions prevented; and
o 120 billion Btu saved.
•	2008 Presidential Green Chemistry Challenge Award Recipients
(http://www.epa.gOv/greenchemistry/pubs/pgcc/past.html#2008)
o Greener Synthetic Pathways Award
Battel le
"Development and Commercialization of Biobased Toners"
o Greener Reaction Conditions Award
Nalco Co.
"3D TRASAR® Technology"
o Designing Greener Chemicals Award
Dow AgroSciences
"Spinetoram: Enhancing a Natural Product for Insect Control"
o Small Business Award
SiGNa Chemistry, Inc.
"New Stabilized Alkali Metals for Safer, Sustainable Syntheses"
o Academic Award
Professor Robert E. Maleczka, Jr., Michigan State University
Professor Milton R. Smith, III, Michigan State University
"Green Chemistry for Preparing Boronic Esters"
•	2007 Presidential Green Chemistry Challenge Award Recipients
(http://www.epa.gOv/greenchemistry/pubs/pgcc/past.html#2007)
o Greener Synthetic Pathways Award
Professor Kaichang Li, Oregon State University
Columbia Forest Products
Hercules Inc.
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"Development and Commercial Application of Environmentally Friendly
Adhesives for Wood Composites"
o Greener Reaction Conditions Award
Headwaters Technology Innovation
"Direct Synthesis of Hydrogen Peroxide by Selective Nanocatalyst
Technology"
o Designing Greener Chemicals Award
Cargill, Inc.
"BiOH™ Polyols"
o Small Business Award
NovaSterilis Inc.
"Environmentally Benign Medical Sterilization Using Supercritical Carbon
Dioxide"
o Academic Award
Professor Michael J. Krische, University of Texas at Austin
"Hydrogen-Mediated Carbon-Carbon Bond Formation"
Read more information on the Green Chemistry Program: http://www.epa.gov/
greenchemistry.
Sustainable Futures
Sustainable Futures, a partnership among OPPT, the chemical industry, and other
stakeholders, offers computerized chemical screening models that enable those developing
chemicals to quickly and cost effectively screen them for hazards and/or risks early in the
development process.
Because Sustainable Futures also enables comparing and contrasting hazard and risk
profiles of chemicals and processes, participation in the program can allow companies to
more quickly commercialize environmentally preferable new chemical products and identify
safer alternatives for existing chemical products.
Training and follow-up assistance (http://www.epa.gov/oppt/sf/meetings/train.htm) in the
proper use of these screening models is offered now on a fee-for-service basis by Agency
grantees that have worked closely with EPA on the Sustainable Futures Initiative.
Accomplishments
• Interest continues in Sustainable Futures with more than 80 people, including
representatives of 30 chemical companies, taking training during 2007 in the use,
interpretation and applicability of Sustainable Futures chemical screening models.
Participants in the training sessions (http://www.epa.gov/oppt/sf/meetings/
train.htm) also included government scientists from Australia, Europe (Poland,
Germany, Slovakia, and the Netherlands) and Japan, and scientists from several
consulting firms.
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•	Approximately 11 percent of 2007 through June 2008 New Chemical pre-
manufacture notifications were independently evaluated by submitters at the
research and development stage using the Sustainable Futures tools.
•	As of December 2007, five companies participating in the Sustainable Futures
Initiative have graduated and become eligible to receive regulatory relief for
prescreened low-hazard, low-risk New Chemical Notices
(http://www.epa.gov/oppt/sf/pubs/benefits.htm).
•	In 2007 a new Sustainable Futures Web site was posted at http://www.epa.gov/
oppt/sf/, which has a straightforward front-page index with links to the
SustainableFutures' models, training materials, and more.
•	Since the public release of the PBT Profiler (http://www.epa.gov/oppt/sf/tools/
methods.htm#m6) in December 2002 through June 2008 stakeholders have
conducted more than 160,000 independent PBT screening assessments, making
OPPT's PBT Profiler one of the most widely used chemical screening tools.
Collaborating with stakeholders, OPPT created the PBT Profiler, an online computer
model that allows users to receive quantitative estimates of the environmental
persistence (P), bioconcentration potential (B) and toxicity (T) of chemicals.
•	The Synthetic Organic Chemical Manufacturers Association (SOCMA) sponsored a
training session on the Sustainable Futures models in August 2007 and additional
sessions are planned as called for in the 2006 Memorandum of Understanding (MOU)
between EPA and SOCMA. The goal of the MOU is to provide training and technical
assistance to companies and other stakeholders interested in learning how to use
Sustainable Futures tools.
•	Several consultants have expressed interest in becoming providers of fee-for-service
training (http://www.epa.g0v/0ppt/sf/meetings/train.htm#partners) in the
Sustainable Futures risk screening methods.
AIM—New Analog Tool
OPPT is evaluating a new tool, the Analog Identification Methodology (AIM), which will help
stakeholders conduct human health hazard assessments by identifying closely related
structures with test data.
Accomplishments
•	An initial beta test was completed in 2007 and enhancements have been made based
on comments. A new version of the program has been completed with a revised user
interface, additional structure entry features, and enhancements to the searching
algorithm. AIM will undergo Agency review during 2008 and is expected to be
released to the public in 2009.
Read more information on Sustainable Futures (http://www.epa.gov/oppt/sf) and AIM
(http://www.epa.gov/oppt/sf/presentations/sf/sf-aimla.pdf).
Resource Conservation Challenge
The Resource Conservation Challenge (RCC) (http://www.epa.gov/epawaste/rcc/index.htm)
is a national effort to conserve natural resources and energy by managing materials more
efficiently. RCC partners (http://www.epa.gov/epawaste/partnerships/index.htm) with
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government, industry, businesses, and others to find smarter, faster ways to accomplish
RCC goals.
At EPA, RCC is a joint effort among OPPT, the Office of Solid Waste, and EPA Regions to
work on and coordinate efforts to:
•	Promote more flexible and protective ways to prevent pollution
•	Promote recycling and reuse of materials
•	Reduce the use of toxic chemicals
•	Conserve energy and materials
OPPT has the lead on three projects that are key to achieving RCC goals:
•	Reducing Toxic Chemicals of National Concern (TCNC)
•	Federal Electronics Challenge (FEC) (http://www.federalelectronicschallenge.net/)
•	Electronic Products Environmental Assessment Tool (EPEAT)
(http://www.epa.gov/epp/pubs/products/epeat.htm)
TCNC is a key strategy to achieve RCC's overarching goal of eliminating or reducing
chemicals of national concern from commercial products, waste streams, and industrial
releases.
Accomplishments
•	The TCNC project established a process with relevant manufacturers, processors,
users, and other stakeholders to identify, implement, and realize reduction
opportunities.
•	As part of the TCNC project, OPPT's Design for the Environment (DfE) Program
(http://www.epa.gov/dfe/) and EPA Region 5 created the voluntary Safer Detergents
Stewardship Initiative (SDSI) (http://www.epa.gov/dfe/pubs/projects/formulat/
sdsi.htm) to promote safer surfactants that degrade quickly into non-toxic
byproducts.
As part of this project, EPA Region 5's Laboratory developed, during 2007, final highl-
and low-level detection methodologies and shared information with EPA Regions and
states regarding monitoring/regulating Alkyl Phenol Ethoxylates (APEs), which are
used as surfactants in soaps and detergents. APEs might biodegrade under anaerobic
conditions to alkylphenols which persist in the environment and are considered toxic
to aquatic organisms. SDSI will encourage the manufacture and use of safer
surfactants, reducing the amount of APE surfactants in the environment.
•	In 2007, EPA evaluated information collected as part of a TCNC project to reduce
toxic pollutants in refining petrochemical processes. The project focuses on use of
advanced detection technology and engineering best practices in the refinery setting
to identify and prevent both continuous and episodic releases of targeted highly
reactive volatile organic compounds (HRVOCs) and hazardous air pollutants (HAPs).
As part of the project, a study by Dr. David Allen, of the University of Texas, under
contract to EPA, found greater than expected emission levels of HRVOCs/HAPs,
particularly benzene, in Texas.
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•	Chemical and engineering alternatives for solvents and other toxic chemicals used in
pharmaceutical manufacturing were identified through the TCNC Reduction of Toxic
Chemical Use and Waste in Pharmaceutical Manufacturing Project. OPPT's Green
Engineering program and EPA Regions 2 and 3 participated in the project which,
during 2007:
o Built a working partnership between EPA, the U.S. Food and Drug
Administration (FDA), industry, and academia.
o Conducted successful workshops on solvent-use reduction.
o Hosted a video conferencefor an audience of pharmaceutical industry
academia, and government representatives at the EPA and FDA.
o Sponsored a related conference in Puerto Rico.
•	As part of the TCNC project, OPPT's DfE program began conducting combustion
testing in 2007 on printed circuit board materials with different flame retardants
through the Flame Retardants in Printed Circuit Boards Project. DfE also began
assessing alternatives for the flame retardant Tetrabromobisphenol A, which is the
largest-volume flame retardant produced, and is the primary flame retardant for
printed circuit boards.
Through this project EPA has developed a partnership with electronics, board and
laminate, and chemical industry, environmental groups, universities and government
agencies to evaluate viable chemical substitutes for flame retardants. DfE will
complete a partnership report in 2008.
Read more information on the Resource Conservation Challenge (http://www.epa.gov/
epawaste/conserve/index.htm) and other sections of this report for additional information
on FEC and EPEAT.
Federal Electronics Challenge
The Federal Electronics Challenge (FEC) is a partnership program that empowers federal
agencies to manage their electronics in an environmentally sound manner during all three
life-cycle phases—acquisition and procurement, operation and maintenance, and end-of-life
management.
The FEC supports efforts to continuously improve environmental stewardship of electronic
assets government-wide in order to better assist federal agencies and facilities in meeting
the requirements of Executive Order 13423 (http://www.epa.gov/epp/pubs/guidance/
executiveorders.htm). The FEC also provides resources and technical assistance to help
federal agencies and facilities improve electronics management throughout the lifecycle.
OPPT manages the FEC program, and coordinates with the Office of the Federal
Environmental Executive (http://www.ofee.gov/), EPA's Office of Solid Waste and Office of
Environmental Information, and all 10 EPA Regions to develop and disseminate information
on best management practices for electronics. The goals of this OPPT program are being
achieved in part by assisting federal agencies and their facilities in:
•	Purchasing environmentally preferable electronic equipment, including computer
desktops, laptops, and monitors registered under the Electronic Product
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Environmental Assessment Tool (EPEAT™) (http://www.epa.gov/epp/pubs/
products/epeat/)
•	Enabling ENERGY STAR power management (http://www.energystar.gov/
powermanagement) features on computers and monitors
•	Extending the life span of equipment through internal reuse and donation
•	Increasing the recovery rate and expanding the infrastructure for environmentally
sound electronics recycling
Accomplishments
•	As of May 2008, FEC had 16 Federal Agency Partners and 186 Facility Partners,
representing more than 644,000 federal employees.
•	Thirty FEC partners received a 2008 FEC Award for their accomplishments in 2007:
o Two partners from two agencies received an FEC Gold Award
o Ten partners from five agencies received an FEC Silver Award
o Eighteen partners from seven agencies received an FEC Bronze Award
Twenty-seven FEC partners received a 2007 FEC Award for their accomplishments in
2006:
o Twelve partners from four agencies received an FEC Gold Award
o Seven partners from four agencies received an FEC Silver Award
o Eight partners from five agencies received an FEC Bronze Award
Award applicants were required to complete specific electronics stewardship activities
in one or more electronics life cycle phases, which are designed to put partners on a
path towards achieving the goals of Executive Order 13423.
•	For Fiscal Year (FY) 2007, FEC partners reported the following activities:
o 80 percent of computer desktops, laptops and monitors purchased or leased
were EPEAT™ Bronze, Silver or Gold-registered
o 71 percent of computers have at least a 4-year life span, with a weighted
average life span of 47 months
o 86 percent of monitors and 69 percent of computers had ENERGY STAR®
features enabled
o 99 percent of non-reusable computers were recycled in environmentally
sound manner
These FY 2007 activities translate into the following environmental benefits, which
are attributable to the work of many different EPA programs—FEC, EPEAT™
(http://www.epa.gov/epp/pubs/products/epeat/index.htm), ENERGY STAR®
(http://www.energystar.gov/), and Plug-In To eCycling
(http://www.epa.gov/epawaste/partnerships/plugin/index.htm):
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o Energy savings of 210,087 megawatt-hours, enough electricity to power
18,526 U.S. households for one year
o Primary material savings of over 137,000 metric tons, equivalent to the
weight of 1,069,182 refrigerators
o Air emission savings of over 860,000 metric tons, including greenhouse gas
emission savings of over 16,000 metric tons of carbon equivalent, equal to
removing 13,043 passenger cars from the road for one year
o Water emission savings of 1,800 metric tons
o Toxic material savings of 10 metric tons, equal to the weight of 5,317 bricks
o Municipal solid waste savings of almost 2,000 metric tons equivalent to the
solid waste generated by 1,002 U.S. households in one year
o Hazardous waste savings of over 830 metric tons, equal to the weight of
415,631 bricks
o Cost savings of $18.2 million
Read more information on the Federal Electronics Challenge:
http://www.federalelectronicschallenge.net/.
EPEAT—Assessing Electronics
The Electronic Products Environmental Assessment Tool (EPEAT) (http://www.epa.gov/epp/
pubs/products/epeat.htm) includes two major elements:
•	A set of environmental performance criteria for computers and monitors that have
been adopted as an American National Standard by the Institute of Electrical and
Electronics Engineers (IEEE) through a voluntary consensus process. The standard is
IEEE 1680 (http://www.epeat.net/Criteria.aspx), which became final and publicly
available in April 2006.
•	A Web-based system that enables three things:
o Manufacturers to declare that their product(s) meet specific environmental
performance criteria;
o The verification of the accuracy of the declarations; and
o A listing of all registered products for purchasers.
The system is managed by the Green Electronics Council
(http://www.greenelectronicscouncil.org/), to which EPA awarded a grant in February 2006.
The grant included funding from OPPT, EPA's Office of Solid Waste, and EPA Regions 2, 5, 9,
and 10. The grant ended in December of 2008, and the Green Electronics Council is now
self-sustaining based on manufacturer registration fees. The Web site housing all vendor
self-declarations that their products meet EPEAT criteria became available for institutional
purchasers to access in July 2006.
Development of EPEAT was prompted by a growing demand by institutional purchasers for
an easy-to-use evaluation tool that allows the selection of electronic products based on
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environmental performance. Supported by EPA, EPEAT was developed by a multi-
stakeholder group, including government, industry, non-governmental organizations and
purchasers. The electronics industry has welcomed EPEAT as a tool to provide a consistent
and harmonized set of environmental criteria for all purchasers and an opportunity to gain
market recognition through environmental leadership.
Accomplishments
•	The second annual report quantifying the environmental benefits of EPEAT purchases
(http://www.epeat.net/FastBenefits.aspx) was issued June 17, 2008, by the Green
Electronics Council.
According to the report, over 109 million EPEAT-registered products were purchased
in 2007, a 150% increase from 2006. In the United States, EPEAT-registered desktop
computers accounted for almost 40% of all desktop computer sales in 2007.
Worldwide purchases of EPEAT-registered desktops, notebooks, and monitors will
result in the following environmental benefits when compared to conventional
products:
o Reduces use of primary materials by 75.5 million metric tons, equivalent to
the weight of more than 585 million refrigerators
o Reduces use of toxic materials, including mercury, by 3,220 metric tons,
equivalent to the weight of 1.6 million bricks
o Eliminates use of enough mercury to fill 482,381 household fever
thermometers
o Avoids the disposal of 124,000 metric tons of hazardous waste, equivalent to
the weight of 62 million bricks
In addition, due to EPEAT's requirement that registered products meet ENERGY STAR
specifications, these products will consume less energy throughout their useful life,
resulting in:
o Savings of 42.2 billion kWh of electricity—enough to power 3.7 million U.S.
homes for a year
o Elimination of the release of 174 million metric tons of air emissions
(including greenhouse gas emissions) and almost 365 thousand metric tons of
water pollutant emissions
o Reduction of 3.31 million metric tons of carbon equivalent greenhouse gas
emissions—equivalent to removing 2,630,000 U.S. cars from the road for a
year
•	EPEAT-registered products must meet 23 mandatory environmental criteria to be
included in the EPEAT Product Registry (http://www.epeat.net/Search.aspx). There
are an additional 28 optional criteria used to determine whether products earn EPEAT
Bronze, Silver, or Gold recognition. As of June 2008, there were 27 manufacturers
with 591 EPEAT-registered products listed the EPEAT Product Registry Web page
located at http://www.epeat.net/Search.aspx, including products from the top sellers
of IT products in the U.S. market. In June 2007, HP and Dell registered the first
EPEAT Gold products, which included desktops and laptops, and the number of
manufacturers with Gold products continues to grow.
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•	OPPT assisted in developing language that was added to the Federal Acquisition
Regulations (FAR) on December 26, 2007, as an interim final rule requiring all
federal purchasers to buy EPEAT registered products.
•	Based on stakeholder demand, EPA has provided partial funding to develop four
additional multi-attribute environmental performance standards for electronic
products: imaging equipment, televisions, servers, and cell phones/PDAs. Work is
currently underway to develop a standard for imaging equipment, and a study group
has formed to consider developing a television standard. The existing computer
standard is also being revised to further strengthen its environmental performance
criteria.
•	Stakeholders have asked EPEAT to expand to both market EPEAT-registered products
to consumers, and to address products of which consumers are the primary
purchasers. Work is underway to explore the best and most economical marketing
approaches to undertake.
Read more information on EPEAT: http://www.epa.gov/epp/pubs/products/epeat.htm.
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Cross-Cutting Programs
The Office of Pollution Prevention and Toxic's (OPPT)
accomplishments in 2007 encompass a range of activities
that provide support across OPPT's individual programs and,
in some cases, enhance other EPA programs. These activities
have helped OPPT improve access to information about
chemicals, assess progress toward achieving program goals,
strengthen collaboration and partnerships with other EPA
programs and stakeholders, and develop tools and models to
improve risk assessment and risk management.
Accomplishments
•	EPA's Community Action for a Renewed Environment Program (CARE) has been
working collaboratively with the Agency's Design for the Environment (DfE)
(http://www.epa.gov/dfe/) program and the Office of Air Quality Planning and
Standards Community Air Toxics Collision Repair Campaign to promote best practices
at auto body and refinishing businesses (http://www.epa.gov/dfe/pubs/projects/
auto/) to reduce emissions of toxic chemicals. They include air toxics such as lead,
chromium, diisocyanates (the leading cause of occupational asthma), ethyl benzene,
toluene, xylenes, and other volatile organic compounds (VOCs). Implementation of
best practices in all 50,000 auto body shops nationwide could reduce air toxics and
VOCs by 174 million pounds per year, while saving businesses money by reducing
paint and solvent costs, minimizing hazardous waste, and protecting the health of
persons in the workplace and surrounding community.
•	Information Technology (IT) Support—OPPT continues to modernize the information
holdings and workflow processes to better enable staff, managers and the public to
manage and evaluate risks. Proceeding under the Agency's Enterprise Architecture
Program, this effort ultimately will result in data being integrated across the office
and all key documents being stored and centrally accessible. The goal is for all
company data submissions to be submitted and processed electronically, utilizing
electronic workflow processes. Current data flows being modernized include the
Inventory Update Reporting and those in the New Chemicals Program. A new
environment called Managed Toxic Substances, or MTS, will be used to implement
electronic processing for OPPT's New Chemicals Program during 2008.
•	OPPT also processes Freedom of Information Act (FOIA) requests related to the Toxic
Substances Control Act and other statutes and policies for which OPPT has
responsibility. During 2007, OPPT processed 55 FOIA requests.
Read the CARE section of this report for more information.
Assessing Results—OMB's PART
The U.S. Office of Management and Budget (OMB) developed the Program Assessment
Rating Tool (PART) in FY 2002 to assess the extent to which federal government programs
are well-designed, well managed and are generating intended results. Fifty-three EPA
programs have been evaluated through PART. Nearly all federal programs have been
evaluated between FY 2002 and FY 2007 with re-evaluations completed as necessary.
Three OPPT programs have undergone PART assessments and are ranked in the top 10
highest among EPA programs assessed to date:
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•	Pollution Prevention (2nd highest)
•	Chemical Risk Review and Reduction (tied for 5th highest)
•	Childhood Lead-Based Paint Risk Reduction (6th highest)
OPPT's Pollution Prevention (P2) Program received an 82.7 percent rating from OMB during
its PART assessment in FY 2006. The assessment helped spur improvements in program
design and integration of performance results across seven P2 programs to achieve national
goals.
OPPT's Childhood Lead-based Paint Risk Reduction Program underwent its initial PART
assessment in FY 2005, obtaining a 79 percent rating from OMB. As a result of the
assessment, the program improved the processes of involving program partners and
integrating EPA headquarters and regional office activities.
PART'S continued recognition of the strength of OPPT's programs reflects the office's
commitment to performance-based management—setting ambitious yet achievable outcome
goals, monitoring progress towards those goals, and using performance information in
making key management decisions. It also reflects the support provided to program
managers from OPPT's financial management system.
Accomplishments
•	In its PART review, OPPT's Chemical Risk Review and Reduction Program received an
80 percent rating from OMB in FY 2007. The Program is currently implementing
several PART follow-up actions to improve performance accountability.
Read more information on PART: http://www.whitehouse.gov/omb/part/.
Community Action for a Renewed Environment
The Community Action for a Renewed Environment (CARE) (http://www.epa.gov/care/)
Program helps communities address multiple sources of toxic pollutants in their
environment through competitive grants and technical assistance. Through CARE, EPA
works with local organizations, including non-profits, businesses, schools and governments,
to create partnerships that implement local solutions to risks posed by pollutants. CARE
works with communities to set priorities for risk-reduction activities and helps to create self-
sustaining, community-based partnerships.
Responsibility for CARE rotates among EPA's major media programs of air, water, waste and
pesticides and toxics. With primary responsibility for the program since January 2007, the
Office of Pesticides, Pollution Prevention and Toxics (OPPTS), of which OPPT is a part, has
sought to better support CARE grantees needing access to its programs, including the Lead
Program, Green Suppliers Network, and Design for the Environment (DfE) to name a few.
OPPT has also increased focus on measuring programmatic results and sharing OPPT tools
and models while coordinating the cross-Agency CARE team.
Accomplishments
•	Since its first round of cooperative agreement awards in 2005, the grants to reduce
toxics in the environment have reached 64 communities in over 32 states and tribes,
totaling $10.4 million.
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•	For 2009, approximately $3 million is available for these community-based
partnerships to reduce pollution at the local level through CARE. In 2008, $2.7
million was made available for 18 communities; in 2007, $3.4 million funded 22
communities.
•	The CARE Program offers two levels of Cooperative Agreements to local
communities: Level I cooperative agreements, ranging from $75,000 to $100,000,
help establish community-based partnerships to develop local environmental
priorities. Level II awards, ranging from $150,000 to $300,000 each, support
communities that have established partnerships and priorities and are implementing
risk reduction activities.
•	In July 2007, EPA former Administrator Stephen Johnson and Centers for Disease
Control and Prevention Director Julie Gerberding signed a formal Memorandum of
Understanding (MOU) (http://www.epa.gov/care/collaboration.htm) to better
coordinate the efforts and resources of the agencies, and announced four pilot
projects across the country. The MOU outlines a collaboration that is working with
state, local, tribal and community groups to achieve the environmental and public
health goals of the agencies.
Read more information on the Community Action for a Renewed Environment (CARE)
program: http://www.epa.gov/care/.
OPPT Tribal Program
OPPT is committed to working in partnership with tribal governments to safeguard and
protect the environment from toxic hazards and to promote pollution prevention in Indian
country. The first priority of the OPPT Tribal Program is continuing to improve
communication to better exchange information regarding environmental concerns and
issues facing Indian country today.
OPPT publishes the OPPTS Tribal newsletter (http://www.epa.gov/oppt/tribal/pubs/
index.html), which features a wide variety of environmental information, perspectives, and
issues that affect American Indian Tribes. This newsletter is sent out to all federally-
recognized tribes, Tribal environmental groups, Tribal colleges, Tribal news media and EPA
Tribal advisory groups and other interested parties.
Accomplishments
•	On February 7, 2007, OPPTS signed a Memorandum of Understanding (MOU) with
Salish Kootenai College and the Confederated Salish Kootenai Tribes, Poison, Mont.,
to:
o Expand opportunities for faculty enrichment, and undergraduate and graduate
student training with emphasis on sciences, technology and related
environmental sciences.
o Help achieve goals in OPPTS Tribal Strategic Plan (http://www.epa.gov/oppts/
pubs/tribal/tribalplan_signsep804Final.pdf).
o Help support the President's Management Agenda for Advancing the Strategic
Management of Human Capital, and Executive Order 13270 on Tribal Colleges
and Universities.
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•	In 2007, OPPT also developed a list of activities under consideration to implement
the MOU, which was co-sponsored by EPA's Office of Administrator and Resource
Management.
•	In June 2008, OPPT published a two-volume newsletter on Alaska.
Read additional information on OPPT's Tribal Program: http://www.epa.gov/oppt/tribal/.
Risk Assessment Tools—RSEI Model
The Risk-Screening Environmental Indicators (RSEI) (http://www.epa.gov/oppt/rsei/) is a
computer-based screening tool developed by OPPT that analyzes risk factors to put Toxics
Release Inventory (TRI) (http://www.epa.gov/tri/) release data into a chronic health
context. RSEI is often used by government regulators, communities, journalists, industry
and others to examine trends, identify important emissions situations for follow-up, support
community-based projects and initially screen potential impacts of emissions.
Accomplishments
•	In 2007, OPPT updated the model and a new version, RSEI 2.1.5
(http://www.epa.gov/oppt/rsei/pubs/get_rsei.html), was released in January 2008,
which has data covering 1996-2005 and includes new features:
o Reporting facilities located using EPA's Locational Reference Tables (LRT)
o Additional site-specific information
o Chromium speciation
o Metals and metal compounds combined
o Updated toxicity weights
•	In 2007, OPPT worked with a variety of clients to interpret and utilize risk-related
information on industrial releases.
•	In 2007, OPPT presented the RSEI model to various groups, including the American
Petroleum Institute and at the annual TRI Conference, sponsored by EPA's Office of
Environmental Information and the Environmental Council of the States.
•	OPPT held workshops to train EPA regional staff on the RSEI model.
o October 2007 for EPA Region 4
o November 2007 for EPA Region 5
Read more information on the Risk-Screening Environmental Indicators Model:
http://www.epa.gov/oppt/rsei/.
OPPT Exposure Models
OPPT has a number of computer-based models which are used in the absence of measured
data to estimate exposure. The Estimated Programs Interface (EPI) Suite™
(http://www.epa.gov/oppt/exposure/pubs/episuite.htm) model is used to provide
screening-level estimates of physical/chemical and environmental fate and transport
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properties for chemicals. These properties are important in understanding how a chemical
will behave in the environment and are informative in assessing exposure. OPPT uses this
information to support regulatory decisions in its New Chemicals Program and in assessing
existing chemicals.
The Internet Geographic Exposure Modeling System (IGEMS) (http://www.epa.gov/oppt/
exposure/pubs/gems.htm) brings together in one system several EPA environmental fate
and transport models and some of the environmental data needed to run them.
ReachScan (http://www.epa.gov/oppt/exposure/pubs/reachscan.htm) estimates surface
water chemical concentrations and populations served by drinking water utilities
downstream from industrial facilities.
Accomplishments
•	EPA received the final report of the Science Advisory Board peer review of EPI
Suite™ (http://yosemite.epa.gov/sab/sabproduct.nsf/
CCF982BA9F9CFCFA8525735200739805/$File/sab-07-011.pdf) in September 2007,
which included comments on current and potential uses of the software and
recommendations for improvements in the software's scope, accuracy, and ease of
operations. OPPT has begun to implement changes to EPI Suite™ based on
comments received from the SAB.
•	In 2007 OPPT worked on developing a new version of IGEMS, which will be available
to the public in June 2008. The new version will include features designed to enable
communities to use IGEMS for local assessments.
•	OPPT has identified an existing model which can be customized to perform the
functions of the old ReachScan, and is investigating approaches for using the
National Hydrography Dataset (http://nhd.usgs.gov/).
Read more about EPI Suite™ (http://www.epa.gov/oppt/exposure/pubs/episuite.htm),
IGEMS (http://www.epa.gov/oppt/exposure/pubs/gems.htm), and ReachScan
(http://www.epa.gov/oppt/exposure/pubs/reachscan.htm) and other OPPT exposure models
(http://www.epa.gov/oppt/exposure/).
Oncologic™, ECOSAR and AQUATOX
Tools and models are used in the hazard, exposure and risk assessment processes to
evaluate both new and existing chemicals under TSCA when certain data are missing. OPPT
uses and promotes the use of these models, including OncoLogic™ for health hazard
evaluation, and ECOSAR and AQUATOX for environmental effects and fate.
OncoLogic™ (http://www.epa.gov/oppt/newchems/tools/oncologic.htm) is a stand alone
computer program that evaluates the potential that a chemical may cause cancer.
OncoLogic, which provides the scientific rationale for each evaluation along with the results,
has been peer reviewed and runs on a Windows® PC. EPA's Web site provides a
downloadable version of OncoLogic™ along with extensive information on proper use of the
method. OncoLogic analyzes a chemical structure to determine the likelihood that it may
cause cancer by applying the rules of structure activity relationship (SAR) analysis and
incorporating knowledge of how chemicals cause cancer in animals and humans. OncoLogic
is comprised of four subsystems that evaluate fibers, metals, polymers, and organic
chemicals of diverse chemical structures.
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ECOSAR (Ecological Structure Activity Relationships) (http://www.epa.gov/oppt/newchems/
tools/21ecosar.htm) is a personal computer software program that is used to estimate the
toxicity of chemicals used in industry and discharged into water. The program predicts the
toxicity of industrial chemicals to aquatic organisms such as fish, invertebrates, and algae
by using Structure Activity Relationships (SARs). The program estimates a chemical's acute
(short-term) toxicity and, when available, chronic (long-term or delayed) toxicity. ECOSAR
also allows access to hundreds of SARs developed for 48 chemical classes. The SARs
contained within the program are developed using test data. Many of the SAR predictions
have been validated.
AQUATOX (http://www.epa.gov/waterscience/models/aquatox/) is a simulation model for
aquatic systems. AQUATOX predicts the fate of various pollutants, such as nutrients and
organic chemicals, and their effects on the ecosystem, including fish, invertebrates, and
aquatic plants. This model is a valuable tool for ecologists, biologists, water quality
modelers, and anyone involved in performing ecological risk assessments for aquatic
ecosystems.
Accomplishments
•	OncoLogic™: OPPT is now providing a downloadable version of OncoLogic™
(http://www.epa.gov/oppt/newchems/tools/oncologic.htm), a powerful predictive
screening method, at no cost to interested users wishing to evaluate cancer potential
of chemicals. The U.S. Food and Drug Administration OncoLogic™ recently published
a study affirming the model's predictive capability
(http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WPT-4PSC2BN-
l&_user=14684&_coverDate=02%2F29%2F2008&_alid=729502692&_rdoc=l&_fmt
= high&_orig=search&_cdi=6999&_sort=d&_docanchor=&view=c&_ct=l&_acct=C00
0001678&_version=l&_urlVersion=0&_userid = 14684&md5=0c992182870390762 la
05e4bc790313b).
OPPT shared OncoLogic™ with the European Union. In addition, the method has been
selected for future inclusion in the Organization for Economic Cooperation and
Development (OECD) Quantitative Structure Activity Relationships ((Q)SAR)
Application Toolbox (http://www.oecd.org/document/23/
0,3343,en_2649_34365_33957015_l_l_l_l,00.html) for cancer.
•	ECOSAR: OPPT scientists are working to make numerous improvements to ECOSAR
(http://www.epa.gov/oppt/newchems/tools/21ecosar.htm) including the addition of
new SARs (inorganic and organometallic chemicals, and 20 new chemical classes
with excess toxicity), and enhancements for existing SARs:
o All SARs for excess toxicity have been recalculated using the Kow value from
EPI Suite™ (http://www.epa.gov/oppt/exposure/pubs/episuite.htm).
o All classes now have at least six SARs for freshwater organisms.
o Test data have been added to existing SARs.
OPPT scientists improved the ECOSAR decision tree which selects SAR(s) from
"structure" and they have added "Help" screens for every SAR showing data used in
SAR regression equations, data used in SAR but not in regression equations, and
data for chemicals which fit the SAR class but are not used.
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OPPT shared ECOSAR with the OECD, which added
the method to the (Q)SAR Application Toolbox
(http://www.oecd.Org/document/23/0,3343,en_2649
_34365_33957015_l_l_l_l,00.html) for aquatic
toxicity. Work in progress includes the addition of
structural alerts for herbicides, insecticides,
fungicides, and other pesticides. ECOSAR version
0.99g is available as a stand-alone model and version
0.99h has been incorporated into the EPI Suite of
models. The next version of ECOSAR is expected to
have over 2,000 SARs.
• AQUATOX: During 2005, 2006, and 2007, OPPT
funded the development of a version of AQUATOX
(http://www.epa.gov/waterscience/models/aquatox/)
relating to estuaries, and a comparison of predictions of AQUATOX on the fate and
effects of nonylphenol and pefluoralkylated surfactants. In addition, EPA's Office of
Water (OW) and OPPT jointly funded the inclusion of the Office of Research and
Development—Gulf Breeze Lab "Interspecies Correlation Estimations (ICE) for Acute
Toxicity to Aquatic Organisms and Wildlife" into AQUATOX. These enhancements
have been included in Release 3 of AQUATOX, which has been beta tested and is
scheduled to be peer reviewed and released in 2008.
Read more information on OncoLogic™ (http://www.epa.gov/oppt/newchems/tools/
oncologic.htm), ECOSAR (http://www.epa.gov/oppt/newchems/tools/21ecosar.htm), and
AQUATOX (http://www.epa.gov/ost/models/aquatox) and other OPPT exposure assessment
tools and models (http://www.epa.gov/oppt/exposure/).
We honor Vince Nabliolz—a
cherished member of the OPPT
family for over 25 years—who
died in February 2008. Vince
made significant contributions
to the cause of protecting the
environment as an expert
environmental toxicologist and
quantitative structure activity
relationships analyst. Vince
will be remembered as a
trusted colleague and friend
with a great sense of humor
and passion for his work.	
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