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US EPA CSS-HERA
Board of
Scientific
Counselors
Chemical Safety
Subcommittee
Meeting
US EPA CSS-HERA BOSC Meeting - February 2-5, 2021
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The work presented within represents US EPA Office of Research and Development research
activities. Material includes both peer reviewed, published results and work-in-progress
research. Please do not cite or quote slides.
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Table of Contents
CompTox Chemicals Dashboard (Antony Williams) 3
The work presented within represents US EPA Office of Research and Development research activities. Material
includes both peer reviewed, published results and work-in-progress research. Please do not cite or quote slides.
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CompTox Chemicals Dashboard
Antony John Williams
williams.antony@epa.gov
Center for Computational Toxicology and Exposure, US-EPA, RTP, NC
February 3rd 2021: Board of Scientific Counselors meeting
The views expressed in this presentation are those of the authors and do not necessarily reflect the views or policies of the U.S. EPA
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CompTox Chemicals Dashboard
https://comptox.epa.gov/dashboard
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A publicly accessible website delivering access
• ~883,000 chemicals with related property data
• Experimental and predicted physicochemical property data
• Experimental Human and Ecological hazard data
• Integration to "biological assay data" for 1000s of chemicals
• Information regarding consumer products containing chemicals
• Links to other agency websites and public data resources
• "Literature" searches for chemicals using public resources
• "Batch searching" for thousands of chemicals
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Online Materials
&EFA
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Lots of resources available
• Presentations: https://tinvurl.com/w5hqs55
• Communities of Practice Videos: https://rb.qy/qsbno1
• Manual: https://rb.qy/4fqydc
• Latest News: https://comptox.epa.gov/dashboard/news
info
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Antony Williams
ANNOUNCEMENT
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Where are we now? Celebrating the 10th Incremental Release of the CompTox
Chemicals Dashboard
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CompTox Chemicals Dashboard primer videos
The CompTox Chemicals Dashboard is a one-stop-shop for chemistry, toxicity and exposure information for over 875,000 chemicals. Data
and models within the Dashboard also help with efforts to identify chemicals of most need of further testing and reducing the use of
animals in chemical testing.
Explore the wealth of data and features available in the CompTox Chemicals Dashboard with these insructional videos narrated by EPA
scientists.
General Chemistry and Search Capabilities
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Conclusion
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Agency
Dashboard access to data for ~883,000 chemicals (and growing)
Data aggregation for ALL data sources continues unabated
Flexible search capabilities continue to expand release-to-release
Expansion of new modules continues with
prototype development
The application is being totally rearchitected
at present to also develop a Public API
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Functional Use Data
Summarized In Vivo Data
In Vitro Assay Data (ToxCast, Tox2l)
Experimental &
Predicted Property Data
Models |
Documentation for
Predictive Models
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• Contact: Williams.Antonv@epa.gov
• Feedback and follow-up is
welcomed! Your questions help
• The dashboard is based on the
efforts of many more team
members than us. Many
collaborators provide data also.
SEPA
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EPA's Centerfor Computational Toxicology and Exposure
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