Draft Risk Evaluation for Cyclic Aliphatic Bromides Cluster (HBCD) Data Quality Evaluation of Environmental Releases and Occupational Exposure Data


vvEPA
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
United States	Office of Chemical Safety and
Environmental Protection Agency	Pollution Prevention
Draft Risk Evaluation for
Cyclic Aliphatic Bromides Cluster
(HBCD)
Systematic Review Supplemental File:
Data Quality Evaluation of
Environmental Releases and Occupational Exposure Data
CASRN
NAME
25637-99-4
Hexabromocyclododecane
3194-55-6
1,2,5,6,9,10-Hexabromocyclododecane
3194-57-8
1,2,5,6-T etrabromocy clooctane
June 2019

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This document is a compilation of tables for the data extraction and evaluation for Cyclic
Aliphatic Bromides Cluster (HBCD). Each table shows the data point or set or information
element that was extracted and evaluated from a data source in accordance with Appendix D
of the Application of Systematic Review in TSCA Risk Evaluations. If the source contains more
than one data set or information element, the review provides an overall confidence score for
each data set or information element that is found in the source. Therefore, it is possible that a
source may have more than one overall quality/ confidence score.
Table of Contents
Releases to the Environment
Occupational Exposure
Facility
Page
3
134
305
Explanatory Notes
These explanatory notes provide context to understand the short comments in the data evaluation tables.
Domain
Metric
Description of Comments Field
Reliability
Methodology
Indicates the sampling/analytical methodology, estimation method, or
type of publication
Repre sentativene ss
Geographic Scope
Indicates the country of the study, publication, or underlying data
Applicability
Indicates whether the data are for a condition of use within scope of the
Risk Evaluation
Temporal Representativeness
Provides the year of study, publication, or underlying data
Sample Size
Describes the distribution of the sample or underlying data
Accessibility / Clarity
Metadata Completeness
Describes the completeness of the metadata
Variability and Uncertainty
Metadata Completeness
Indicates if study or publication addresses variability and uncertainty of
the data or information
2

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Releases to the Environment
3

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Source Citation: Kemmlein, S.,Hahn, 0.,Jann, O.. 2003. Emissions of organophosphate and brominated flame retardants from selected
consumer products and building materials. Atmospheric Environment.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID I3I377
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Commercial Use
Insulation products in buildings
Emission from EPS and XPS insulation samples from manufacturers,
measured in chamber tests
Air
See table 5. Emission is ng of HBCD per m2 of insulation per hour. EPS
= 4 ng/m2-h and 1 ng/m2-h. XPS = 29 ng/m2-h and 0.1 ng/m2-h.
Measured
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Medium x 1
Represents release in a chamber and may not be fully repre-
sentative of the circumstances during actual use
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Germany
High X 2 2 Occupational scenario (use of insulation in offices).
Medium x 2 4 2003
Medium X 1 2 There are two insulation samples with four test results
cahracterized but may not be representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Release circumstances are fully characterized
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Discusses how sample type, chamber temperature, and cham-
ber size may affect results
Overall Quality Determination^
High

1.6

Continued on next page
4

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— continued from previous page
Source Citation:	Kemmlein, S.,Hahn, 0.,Jann, O.. 2003. Emissions of organophosphate and brominated flame retardants from selected
consumer products and building materials. Atmospheric Environment.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	I3I377
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

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Source Citation:	ToxNet Hazardous Substances Data, Bank. 2017. HSDB: Hexabromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970277
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr)
Waste Treatment Method:
All
HBCD in sewage sludge from EPA's 2001 National Sewage Sludge Survey
Sewage sludge to Biosolids, land applications, incineration, landfill
Water, Land
Measured
101-127 kg/yr to biosolids; 49.9-75.9 to land application; 20.8-26 to in-
cineration; 17.7-20.9 kg/yr to landfill
Sewage sludge to Biosolids, land applications, incineration, landfill
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Medium
Medium
Low
XX XX
1
2
2
1
1
4
4
3
US
Captures releases from all possible stages, some of which are
not in scope
2001
Sample size not listed, just cites the National Sewage Sludge
Survey
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1
3
The report does not address variability or uncertainty with
respect to this data element.
Overall Quality Determination^
Medium


1.9


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
6

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Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Number of Sites:
Processing
EPS /XPS Compounding and converting
Water, Land, Air, Incineration
Loss fractions cited from the 2004 Plastics Compounding and Converting
ESD
Estimated
2004 Plastics Compounding and Converting ESD
2004 Plastics Compounding and Converting ESD
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
1	Information is from 2004 Plastics Compounding and Convert-
ing ESD
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1
Medium x 2
Medium x 2
Low	x 1
2	OECD
4	EPS compounding not in scope, but other scenarios are
4	2004
3	Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 Limited discussion on uncertainty and variability
Overall Quality Determination^
Medium
1.9

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
7

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Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Commercial Use
Insulation products in buildings
Life of EPS /XPS insulation
Air and water
Estimated
1.4 (Air) and 1.4 (Water)
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium	x 1
High	x 2
High	x 2
Low	x 1
2	Australia
2	Occupational scenario (use of insulation in offices).
2	2012
3	Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 Discusses variability and uncertainty
Overall Quality Determination^
High

1.3

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

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Source Citation:	2014. The 2012 annual effluent guidelines review report.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3860559
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr)
All
Data from the United Kingdom indicate that the primary sources of
HBCD release are fugitive emissions during its manufacture and subse-
quent use in products, leaching from landfills, and incinerator emissions
50 percent to WWT, 29 percent surface water, 21 percent air
Measured
3100
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
EU
Metric 3:
Applicability
Medium
X
2
4
Captures releases from all possible stages, some of which are






not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Low
X
1
3
Information stated from Europe, unknown sample size
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
High
X
1
1
Discusses variability and uncertainty with regards to limita-






tions on how European data can be applied to US
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
9

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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Releases to the Environment; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Disposal
Insulation products in buildings
Building and construction waste
Information from industry shows that, in 1992, out of the total
construction- and demolition (C&D) waste, plastic waste was 0.4 per-
cent of the weight. EPS and XPS were representing about 3 percent of
the plastic waste and therefore 0.01 percent of the total building waste.
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
In scope
Metric 4: Temporal Representativeness
Low
X
2
6
1992
Metric 5: Sample Size
Low
X
1
3
Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
Medium

1.8

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
HIPS similar but not in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
High
x 1
1
Statistical distribution of samples is fully characterized. Sam-
pie size is sufficiently representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Release Days per Year:
Number of Sites:
Processing
Formulation of EPS and HIPS
WW, surface water, air
Estimated for sites that did not provide data using the 90th percentile
of measured values from sites that did provide data
Table 3-6 = 22.8 (surface water), 2.2 (air)
300
6
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
HIPS similar but not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
High
X
1
1
Statistical distribution of samples is fully characterized. Sam
pie size is sufficiently representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
12

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
Use is in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
High
x 1
1
Statistical distribution of samples is fully characterized. Sam-
pie size is sufficiently representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.1

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

1.1

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Europe
High X 2 2 Use is in scope
High x 2 2 2008
Low X 1 3 Distribution of samples characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

1.1

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

1.1

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

1.1

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Source Citation: Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970747
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Commercial Use
Insulation products in buildings
surface water, WW, air
release factor = 8.4E-06; 5 ug/m2 insulation/yr
estimates taken from sources
Table 3-33 = 54 (air), 0 (surface water and WW)
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
Occupational scenario (use of insulation in offices).
Metric 4: Temporal Representativeness
Medium
X
2
4
sources date back to 2002
Metric 5: Sample Size
Low
X
1
3
Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.6

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Source Citation: Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970747
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Disposal
Insulation products in buildings
demolotion of buildings
30 percent of boards recycled, requiring manual deconstruction of the
structures. The remaining 70 percent of material was disposed of, and
these buildings were assumed not to be manually deconstructed,
incineration
5E-06 release factor from incineration to WW or air
estimated
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope Medium x 1
Applicability High x 2
Temporal Representativeness High x 2
Sample Size Low x 1
2 Europe
2 Use is in scope
2 2008
3 Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Europe
High X 2 2 Use is in scope
High x 2 2 2008
Low X 1 3 Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Europe
High X 2 2 Use is in scope
High x 2 2 2008
Low X 1 3 Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

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Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Number of Sites:
Processing
EPS /XPS Converting
Water, Land, Air, Incineration
Loss fractions cited from the 2004 Plastics Converting ESD
Estimated
2004 Plastics Converting ESD
2004 Plastics Converting ESD
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from 2004 Plastics Converting ESD
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
OECD
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2004
Metric 5:
Sample Size
Low
x 1
3
Unknown
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Medium
x 1
2
Limited discussion on uncertainty and variability
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
23

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Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Release Days per Year:
Processing
Cutting of EPS boards
50 percent to surface water and 50 percent to air or landfill
100 g/tonnes HBCDD from cutting of boards
Estimated
95 percent of the particles generated during cutting operations are as-
sumed to end up in waste.
?230 days/yr
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
Europe
Use is in scope
2003
Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
24

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
Sawing and cutting of EPS and XPS boards
50 percent to surface water and 50 percent to air or landfill
445 g particles per tonne EPS being released during sawing of EPS
boards; 5 g XPS/tonne XPS sawed; 100 g EPS/tonne cut with hot wire
Measured
95 percent of the particles generated during cutting operations are as-
sumed to end up in waste.
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
Europe
Use is in scope
2003
Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
25

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Use
cutting of EPS boards at construction sites
50 percent to surface water and 50 percent to air
10 g particulates/tonnes EPS
Estimated - During professional use (i.e.at construction sites) it is esti-
mated that only 10 percent of boards are cut
250
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
Use is in scope
Metric 4: Temporal Representativeness
Medium
X
2
4
2003
Metric 5: Sample Size
Low
X
1
3
Unknown
Domain 3: Accessibility/Clarity





Metric 6: Metadata Completeness
High
X
1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty





Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the





results. Uncertainty is well characterized.
Overall Quality Determination^
High


1.6

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
26

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Use
cutting of XPS boards at construction sites
50 percent to surface water and 50 percent to air
5 g XPS particlesper tonne XPS
Estimated
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
Europe
Use is in scope
2003
Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
27

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970748
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Commercial Use
Insulation products in buildings
service life of EPS boards at construction sites
water, land, incineration
No loss of HBCD is expected to occur in the foam during service life,
even when exposed to natural light.
The service life of the boards is estimated as 30 to 100 years.
365
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Europe
High X 2 2 Occupational scenario (use of insulation in offices).
Medium x 2 4 2003
Low X 1 3 Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Daily Release Quantity (kg/day):
Annual Release Quantity (kg/yr):
Release Days per Year:
Commercial Use
Insulation products in buildings
service life of EPS boards at construction sites
air
release factor = 8.4E-06
over a 100 year service life
1.8E-05 kg/day
6.7E-03 kg/yr
365
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium	X	1	2	Europe
High	X	2	2	Occupational scenario (use of insulation in offices).
Medium	x	2	4	2003
Low	X	1	3	Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
29

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium X 1 2 Europe
High X 2 2 Use is in scope
High x 2 2 2008
Low X 1 3 Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Disposal
Insulation products in buildings
demolition - disposal of boards
30 percent of boards recycled, requiring manual deconstruction of the
structures. The remaining 70 percent of material was disposed of, and
these buildings were assumed not to be manually deconstructed,
incineration
5E-06 release factor from incineration to WW or air
taken from EU RAR
330
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope	Medium	x 1	2
Applicability	High	x 2	2
Temporal Representativeness	High	x 2	2
Sample Size	Low	x 1	3
Europe
Use is in scope
2008
Distribution characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3


Continued on next
page


31

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970748
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
32

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified, Part 2.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970753
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
formulation of EPS beads
Waste-water from the reaction process
wastewater
2 g per tonne of HBCDD used
informtation from industry
?330 days
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
EPS compounding not in scope but may provide insight into
XPS compounding
Metric 4:
Temporal Representativeness
High
X
2
2
2012
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified, Part 2.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970753
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
formulation of EPS beads
waste packaging contaminated with the substance, filters, filter dust and
off-spec product
release of less than 0.001 percent of the flame retardant put into the
incinerator
incineration
<0.5 percent of the HBCDD used to incineration
informtation from industry
?330 days
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High	x 1	1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
EPS compounding not in scope but may provide insight into
XPS compounding
Metric 4:
Temporal Representativeness
High
X
2
2
2012
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High 1.6

Continued on next page
34

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified, Part 2.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970753
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
35

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2017. Chemical safety report: Hexabromocyclododecane and all major diastereoisomers identified, Part 2.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970753
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
formulation of EPS beads
landfill
1 g per tonne of HBCDD used
informtation from industry
?330 days
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
EPS compounding not in scope but may provide insight into
XPS compounding
Metric 4:
Temporal Representativeness
High
X
2
2
2012
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970750
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
manufacturing
manufac turing
Estimated - see table 3
2 kg/yr (air); <1 kg/y (WW)
1
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Manufacturing not in scope but maybe can be applied to im-

portation
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
37

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Processing
Cutting of EPS boards
Cutting of EPS boards
air
100 g/tonnes HBCDD from cutting of boards
taken from EU RAR
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
Use is in scope
Metric 4: Temporal Representativeness
High
X
2
2
2008
Metric 5: Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity





Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7: Metadata Completeness
Medium
X
1
2
limited discussion
Overall Quality Determination^
High


1.4

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
38

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Use
cutting of XPS boards at construction sites
air
5 g XPS particlesper tonne XPS
taken from EU RAR
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
39

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 3970750
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Commercial Use
Insulation products in buildings
service life of EPS and XPS boards at construction sites
air
measured
70 kg/year
EVALUATION

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
XPS Compounding /Masterbatch
air, wastewater, surface water
Estimated - see table 3
14 kg/y (air), 84 kg/y (WW), 10 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
41

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
EPS and HIPSformulation
air, wastewater, surface water
Estimated - see table 3
30 kg/y (air), 75 kg/y (WW), 330 kg/y (surface water)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
EPS and HIPS compounding not in scope but may provide





insight into XPS compounding
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5: Sample Size
Low
x 1
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 limited discussion
Overall Quality Determination^
Medium
1.7

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
42

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
EPS converting from beads to foam
air, wastewater, surface water
Estimated - see table 3
159 kg/y (air), 128 kg/y (WW), 31 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
43

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Background document for hexabromocyclododecane and all major diastereoisomers identified.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970750
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
XPS converting from beads to foam
air, wastewater, surface water
Estimated - see table 3
146 kg/y (air), 63 kg/y (WW), 16 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
44

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2015. RAC and SEAC Opinion on an application for authorisation for hexabromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970755
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Disposal
Insulation products in buildings
demolition - disposal of EPS boards
incineration
90 g HBCD/tonne EPS boards
proposed by industry
3.20 tonnes/yr (if 32,000 tonnes HBCDD are used)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Not from trusted sources; however, Associated information
does not indicate flaws or quality issues
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2014
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
report provides results, but the underlying methods, data
sources, and assumptions are not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Fully addresses variability and uncertainty
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
45

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2015. RAC and SEAC Opinion on an application for authorisation for hexabromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970755
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Use
construction /installation of EPS boards at consrtuction sites
unknown
10 g HBCD/tonne EPS boards
proposed by industry
1.97 tonnes/yr (if 32,000 tonnes HBCDD are used)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Not from trusted sources; however, Associated information
does not indicate flaws or quality issues
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2014
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
x 1
3
report provides results, but the underlying methods, data
sources, and assumptions are not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Fully addresses variability and uncertainty
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
46

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: European Flame Retardants, Association. 2016. Fireaway! the EFRA newsletter.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3981170
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Disposal
HIPS
household waste
71 percent reused, recycled or composted; 27 percent is incinerated; <1
percent is landfilled
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
The data, data sources, and/or techniques used in the assess-

ment or report are not specified.
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Belgium
Metric 3:
Applicability
Unacceptable
x 2
8
disposal of this material is not in scope and this information

does not seem applicable to in-scope scenarios
Metric 4:
Temporal Representativeness
High
x 2
2
2016
Metric 5: Sample Size
Low
x 1
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Low X 1 3 report provides results, but the underlying methods, data
sources, and assumptions are not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.7.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Duan, H.,Yu, D.,Zuo, J.,Yang, B.,Zhang, Y.,Niu, Y.. 2016. Characterization of brominated flame retardants in construction
and demolition waste components: HBCD and PBDEs. Science of the Total Environment.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3575294
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Disposal
Insulation products in buildings
sorting and crushing
air
Original HBCD constituent in C&D waste is released into the atmo-
sphere during these sorting and crushing operations, and is assumed to
contribute 10 percent of the atmospheric emissions in the demolition
process.
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High x 1	1 Journal article
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
High
X
2
2
disposal in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
High
X
1
1
Statistical distribution of samples is fully characterized. Sam-
ple size is sufficiently representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1 Fully addresses variability and uncertainty
Overall Quality Determination^
High
1.2

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
48

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Duan, H.,Yu, D.,Zuo, J.,Yang, B.,Zhang, Y.,Niu, Y.. 2016. Characterization of brominated flame retardants in construction
and demolition waste components: HBCD and PBDEs. Science of the Total Environment.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3575294
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Disposal
Insulation products in buildings
landfilling of foam insulation
landfill
7039.00 ?g/kg of HBCD found in foam in landfills
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Low
X 1
3
China
Metric 3:
Applicability
High
x 2
2
disposal in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2016
Metric 5:
Sample Size
High
x 1
1
Statistical distribution of samples is fully characterized. Sam-





ple size is sufficiently representative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1 Fully addresses variability and uncertainty
Overall Quality Determination^
High
1.2

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
49

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
EPS compounding
This is the emission factor for a generic site and was determined based
on the 90th percentile of measurements of concentration in the effluent
from the on-site sewer treatment plants of 9 of the total of 13 sites,
water
7.60E-06
taken from 2008 EU assessment (HERO 3970747)
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Low x 1
2 Europe
4 EPS and HIPS compounding not in scope but may provide
insight into XPS compounding
2 2008
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High 1.6

Continued on next page
50

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
51

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Number of Sites:
Processing
EPS compounding
This is the emission factor for a generic site and is equal to the maximum
emission factor calculated from site-specific data that pertain to three
processing steps including formulation of EPS and XPS compounds,
air
7.60E-06
taken from 2008 EU assessment (HERO 3970747)
300
13
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Low x 1
2 Europe
4 EPS and HIPS compounding not in scope but may provide
insight into XPS compounding
2 2008
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
52

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
53

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
EPS compounding
These values are reasonable worst case values that are the sums of emis-
sion factors for handling and compounding solid flame retardants with
particle sizes <40 ?m that are also of relatively high volatility as reported
in OECD (2004b).
water
6.80E-03
taken from 2012 Australian assessment (HERO 3978355)
150
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Low x 1
2 Australia
4 EPS and HIPS compounding not in scope but may provide
insight into XPS compounding
2 2012
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
54

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
55

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
EPS compounding
These values are reasonable worst case values that are the sums of emis-
sion factors for handling and compounding solid flame retardants with
particle sizes <40 ?m that are also of relatively high volatility as reported
in OECD (2004b).
air
2.50E-04
taken from 2012 Australian assessment (HERO 3978355)
150
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Low x 1
2 Australia
4 EPS and HIPS compounding not in scope but may provide
insight into XPS compounding
2 2012
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
56

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
57

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
EPS Converting
These are the emission factors for the generic site and are reported in
OECD (2004b) as the emission factors for organic flame-retardants of
relatively low volatility in partially open plastics conversion processes,
water
3.00E-05
taken from 2008 EU assessment (HERO 3970747)
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope Medium x 1 2
Applicability High x 2 2
Temporal Representativeness High x 2 2
Sample Size Low x 1 3
Europe
in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Continued on next
page

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
59

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
EPS Converting
These are the emission factors for the generic site and are reported in
OECD (2004b) as the emission factors for organic flame-retardants of
relatively low volatility in partially open plastics conversion processes,
air
3.00E-05
taken from 2008 EU assessment (HERO 3970747)
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope Medium x 1 2
Applicability High x 2 2
Temporal Representativeness High x 2 2
Sample Size Low x 1 3
Europe
in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Continued on next
page

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
61

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Previous risk assessments
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
Australia
Metric 3:
Applicability
High
X
2
2
in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2012
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Continued on next page
62

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
63

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Previous risk assessments
Domain 2: Representative

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Continued on next page
64

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
65

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
Compounding of Polystyrene Resin to Produce XPS Masterbatch
This is the emission factor for a generic site and is equal to the maximum
of emission factors calculated from sitespecific data for three sites,
water
7.40E-06
taken from 2008 EU assessment (HERO 3970747)
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
in scope
Metric 4: Temporal Representativeness
High
X
2
2
2008
Metric 5: Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
Compounding of Polystyrene Resin to Produce XPS Masterbatch
This is the emission factor for a generic site and is equal to the maximum
emission factor calculated from site-specific data that pertain to three
processing steps including formulation of EPS and XPS compounds,
air
7.30E-06
taken from 2008 EU assessment (HERO 3970747)
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope Medium x 1 2
Applicability High x 2 2
Temporal Representativeness High x 2 2
Sample Size Low x 1 3
Europe
in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

Continued on next
page

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
68

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
Compounding of Polystyrene Resin to Produce XPS Masterbatch
This is the emission factor for a generic site and is the sum of emission
factors for handling and compounding organic solid flame retardants
with particle sizes <40 ?m that are of relatively medium volatility as
reported in OECD (2004b).
water
6.60E-03
taken from 2011 Canadian assessment
60 or 200
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1
High x 2
High x 2
Low x 1
2 Canada
2 in scope
2 2011
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
69

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
70

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Days per Year:
Processing
XPS converting
These are the emission factors for the generic site and are equal to the
maxima of the emission factors that were derived from site-specific data
but were not explicitly reported. EPA calculated these factors, each of
which is equal to the ratio of total annual releases from 13 sites for which
site-specific data was not reported and the total annual processing rate
for these sites,
water
2.60E-05
1
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1
High x 2
High x 2
Low x 1
2 Europe
2 in scope
2 2008
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
71

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
72

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Days per Year:
Processing
XPS converting
These are the emission factors for the generic site and are equal to the
maxima of the emission factors that were derived from site-specific data
but were not explicitly reported. EPA calculated these factors, each of
which is equal to the ratio of total annual releases from 13 sites for which
site-specific data was not reported and the total annual processing rate
for these sites,
air
5.80E-05
300
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1
High x 2
High x 2
Low x 1
2 Europe
2 in scope
2 2008
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
73

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809277
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.3


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
74

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
All
Total EU 15 emissions of HBCDD. Most emissions (81 percent ) are
estimated to come from the industrial of use of HBCDD in textile back-
coating.
72 percent WW, 22 percent SW, 6 percent air
0.1 percent of PV
taken from 2008 EU assessment (HERO 3970747)
8.7 tonnes/yr
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Captures releases from all possible stages, some of which are






not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-






sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Medium
X
1
2
limited discussion
Overall Quality Determination^
Medium
1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
75

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2011. Proposal for identification of a substance as a CMR Cat 1 or 2, PBT, vPvB, or a substance of an equivalent
level of concern: Proposal for identification of hexabromocyclododecane as a SVHC.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	3970757
EXTRACTION
Parameter	Data
Life Cycle Stage:
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
All
Total EU 15 emissions of HBCDD. Most emissions (81 percent ) are
estimated to come from the industrial of use of HBCDD in textile back-
coating.
72 percent WW, 22 percent SW, 6 percent air
0.1 percent of PV
taken from 2008 EU assessment (HERO 3970747)
8.7 tonnes/yr
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High	x 1	1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Captures releases from all possible stages, some of which are
not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness	Medium x 1	2 limited discussion
Overall Quality Determination^	Medium	1.7
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
76

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
manufacturing
manufac turing
air and wastewater
same as HERO ID 3970750
2 kg/yr (air); 0.73 kg/y (WW)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Previous risk assessments
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
Manufacturing not in scope but maybe can be applied to im-





portation
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5: Sample Size
Low
x 1
3	characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 limited discussion
Overall Quality Determination^
Medium
1.7

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
77

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Commercial Use
Insulation products in buildings
service life of EPS and XPS boards at construction sites
air
same as HERO ID 3970751
70 kg/year
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Previous risk assessments
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Europe
Metric 3: Applicability
High
X
2
2
Occupational scenario (use of insulation in offices).
Metric 4: Temporal Representativeness
High
X
2
2
2008
Metric 5: Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity





Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7: Metadata Completeness
Medium
X
1
2
limited discussion
Overall Quality Determination^
High


1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
78

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
XPS Compounding /Masterbatch
air, wastewater, surface water
same as HERO ID 3970752
14 kg/y (air), 84 kg/y (WW), 10 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
79

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
EPS and HIPSformulation
air, wastewater, surface water
same as HERO ID 3970753
30 kg/y (air), 75 kg/y (WW), 330 kg/y (surface water)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Previous risk assessments
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
EPS and HIPS compounding not in scope but may provide





insight into XPS compounding
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5: Sample Size
Low
x 1
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 limited discussion
Overall Quality Determination^
Medium
1.7

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
80

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
EPS converting from beads to foam
air, wastewater, surface water
same as HERO ID 3970754
159 kg/y (air), 128 kg/y (WW), 31 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
81

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Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Processing
XPS converting from beads to foam
air, wastewater, surface water
same as HERO ID 3970755
146 kg/y (air), 63 kg/y (WW), 16 kg/y (surface water)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Previous risk assessments
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
Europe
Use is in scope
2008
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
82

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Source Citation:
European Flame Retardants, Association. 2013. Fireaway! the EFRA newsletter, Part 2.
Type of Data Source
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID
3981171
EXTRACTION

Parameter
Data
Life Cycle Stage: Disposal
Life Cycle Description (Subcategory of Use): Disposal of packaging
Environmental Media: 97 percent was incinerated while 3 percent went to controlled landfill
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
The data, data sources, and/or techniques used in the assess-

ment or report are not specified.
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Belgium
Metric 3:
Applicability
Unacceptable
x 2
8
disposal of this material is not in scope and this information

does not seem applicable to in-scope scenarios
Metric 4:
Temporal Representativeness
High
x 2
2
2010-2014
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Low X 1 3 provides results, but the underlying methods, data sources,
and assumptions are not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.7.

Parameter
Data
Life Cycle Stage: Disposal /Recycle
Life Cycle Description (Subcategory of Use): Waste of Electric and Electronic Equipment (WEEE)
Disposal /Treatment Method: 12wt percent of collected WEEE plastics and and almost no FR plastics
are currently recycled were recycled in 2010
Annual Release Quantity (kg/yr): 700,000 tons/yr of annual waste WEEE is expected to contain FRs
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X 1
3
The data, data sources, and/or techniques used in the assess-

ment or report are not specified.
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Belgium
Metric 3:
Applicability
Unacceptable
x 2
8
disposal of this material is not in scope and this information

does not seem applicable to in-scope scenarios
Metric 4:
Temporal Representativeness
High
x 2
2
2010-2014
Metric 5: Sample Size Low X 1 3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low x 1
3
provides results, but the underlying methods, data sources,
and assumptions are not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
does not address variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.7.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Gorga, M.,Martinez, E.,Ginebreda, A.,Eljarrat, E.,Barcelo, D.. 2013. Determination of PBDEs, HBB, PBEB, DBDPE,
HBCD, TBBPA and related compounds in sewage sludge from Catalonia (Spain). Science of the Total Environment.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	1676764
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Number of Sites:
All
Wastewater treatment sludge
HBCD measured in anaerobic digestion and activated sludge
Sewage sludge to soil application, compost, dump, thermal drying, agrar-
ian, or dehydration,
water, land, incineration
5.17 - 97.5 ng/g dry weight (dw) (mean - 19.3 ng/g dw)
Measured
0.757 kg/yr
17
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Spain
4	Captures releases from all possible stages, some of which are
not in scope
2 2013
2	Sample size provided with some statitistical information such
as recovery percent and relative standard deviation
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness	Low	X 1	3 The report does not address variability or uncertainty with
respect to this data element.
Continued on next page
85

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— continued from previous page
Source Citation:
Gorga, M.,Martinez, E.,Ginebreda, A.,Eljarrat, E.,Barcelo, D.. 2013. Determination of PBDEs, HBB, PBEB, DBDPE,

HBCD, TBBPA and related compounds in sewage sludge from Catalonia (Spain). Science of the Total Environment.
Type of Data Source
Releases to the Environment; Environmental Release Data;
Hero ID
1676764
EVALUATION

Domain
Metric Rating MWF* Score Comments
Overall Quality Determination^	Medium	1.7
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
86

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Source Citation: Tomko, G.,McDonald, K. M.. 2013. Environmental fate of hexabromocyclododecane from a new Canadian electronic recycling
facility. Journal of Environmental Management.
Type of Data Source Releases to the Environment; Published Models for Exposures or Releases;
Hero ID 1927574
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Annual Release Quantity (kg/yr):
Disposal
Disposal of Waste of Electric and Electronic Equipment (WEEE)
Releases from Canadian recycling facility
Annual releases in Table 2
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
scientifically sound; no errors found
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Unacceptable
High
N/A
X 1
x 2
x 2
2
8
2
N/A
Canada
Out of scope
2013
Parameter is not applicable to models
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Model approach, equations, and choice of parameter values are
transparent and clear
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
Unacceptable
4 Metric Mean Score: 2.0.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
87

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Bsef,. 2009. HBCD hexabromocyclododecane fact sheet.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3981179
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Number of Sites:
Waste Treatment Method:
manufacturing
manufacturing
1
Wastewater from the production process is treated at the plant by an
advanced wastewater treatment facility including filtration, active car-
bon treatment and bio membrane reactor, resulting in effluents that can
be safely discharged.
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Sources arent necessarily trusted but do not seem flawed
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Unacceptable
High
N/A
X 1
x 2
x 2
1
8
2
N/A
US
Out of scope and not applicable to in scope
2009
This metric is not applicable to this data type
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium
x 1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
The report does not address variability or uncertainty
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.2.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
88

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Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	1927576
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Daily Release Quantity (kg/day):
Processing
XPS Thermal Cutting
Thermal cutting operation modeled in a closed sampling system
Particulate (dust)
Release rate per hour during the thermal cutting operation
4.0E12 particles per hour released or 160.4 ug HBCD per hour released
Measured
1.2832E-06
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Switzerland
Metric 3:
Applicability
High
x 2
2
in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
89

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID	1927576
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Daily Release Quantity (kg/day):
Processing
EPS Thermal Cutting
Thermal cutting operation modeled in a closed sampling system
Particulate (dust)
Release rate per hour during the thermal cutting operation
5.0E12 particles per hour released or 249.1 ug HBCD per hour released
Measured
1.9928E-06
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Switzerland
Metric 3:
Applicability
High
x 2
2
in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High
1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
90

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	European Flame Retardants, Association. 2015. Keeping fire in check an introduction to flame retardants used in transport
applications.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3986543
EXTRACTION
Parameter	Data
Life Cycle Stage:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
All
water, air
1.5 grams/ton HBCD (water); 47.3 grams/ton HBCD (air) (2013)
Estimated via industry survey
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Medium
X
1
2
From industry survey
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Captures releases from all possible stages, some of which are






not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
Unknown, but cites sources as recent as 2013
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-






sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
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Source Citation:
Type of Data Source
Hero ID
EXTRACTION
Parameter	Data
Life Cycle Stage:	Disposal
Life Cycle Description (Subcategory of Use):	Disposal of Waste of Electric and Electronic Equipment (WEEE)
Release Source:	The mean concentrations of total HBCDs in the surface soils ranged
from 0.22 to 0.79 and from 0.31 to 9.99 ng/g dw for two surrounding
e-waste recycling sites and industrial areas.
Annual Release Quantity (kg/yr):	estimates of 3.42 kg and 1.84 tonnes for the e-waste recycling areas and
industrial areas (these areas include electronics, textiles, and building
materials)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X 1
2
Release rate is an estimate for entire lifecycle
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Unacceptable
High
High
X 1
x 2
x 2
x 1
3
8
2
1
China
Out of scope
2011
Statistical distribution of samples is fully characterized.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Release data do not include any needed metadata to under-
stand what the data represent and are not usable in the risk
evaluation
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.3.


Continued on next
page


Gao, S.,Wang, J.,Yu, Z.,Guo, Q.,Sheng, G.,Fu, J.. 2011. Hexabromocyclododecanes in surface soils from E-waste recycling
areas and industrial areas in South China: concentrations, diastereoisomer- and enantiomer-specific profiles, and inventory.
Environmental Science and Technology.
Releases to the Environment; Environmental Release Data;
1927645
92

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— continued from previous page
Source Citation:	Gao, S.,Wang, J.,Yu, Z.,Guo, Q.,Sheng, G.,Fu, J.. 2011. Hexabromocyclododecanes in surface soils from E-waste recycling
areas and industrial areas in South China: concentrations, diastereoisomer- and enantiomer-specific profiles, and inventory.
Environmental Science and Technology.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	1927645
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, two of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
93

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Morf, L. S.,Tremp, J.,Gloor, R.,Huber, Y.,Stengele, M.,Zennegg, M.. 2005. Brominated flame retardants in waste electrical
and electronic equipment: substance flows in a recycling plant. Environmental Science and Technology.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 1927802
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Disposal
Disposal of Waste of Electric and Electronic Equipment (WEEE)
Concentration of HBCD in WEEE
17 mg HBCD/kg WEEE
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Should represent loss if WEEE is entirely disposed of
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High x 1 1
Unacceptable x 2 8
Medium x 2 4
High x 1 1
Switzerland
Out of scope
2005
Statistical distribution of samples is fully characterized.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 data include all associated metadata,
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.9.

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Stubbings, W. A.,Harrad, S.. 2014. Extent and mechanisms of brominated flame retardant emissions from waste soft furnish-
ings and fabrics: A critical review. Environment International.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 2528334
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Disposal
waste textiltes
emissions from waste textiles
air
200-3000 mg HBCD/m2 textile-hour
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 Only represents air release from waste textiles
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
UK
Metric 3: Applicability
Unacceptable
X
2
8
Out of scope
Metric 4: Temporal Representativeness
High
X
2
2
2014
Metric 5: Sample Size
High
X
1
1
Statistical distribution of samples is fully characterized.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
data include all associated metadata,
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.9.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
95

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Source Citation: Environment Canada and Health Canada. 2011. Screening assessment report on hexabromocyclododecane. Chemical Ab-
stracts Service Registry Number 3194-55-6. Ottawa, Canada.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 1937209
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Release Estimation Method:
Annual Release Quantity (kg/yr):
All
all packaging waste
disposal of packaging that contained HBCD from manufacturers
landfill
industrial survey
2017 kg/yr (2008); 309 kg/yr (2009)
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X
1
2
Industrial survey is contingent on voluntary participation
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
Canada
Metric 3:
Applicability
Medium
X
2
4
Captures releases from all possible stages, some of which are

not in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2011
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Environment Canada and Health Canada. 2011. Screening assessment report on hexabromocyclododecane. Chemical Ab-
stracts Service Registry Number 3194-55-6. Ottawa, Canada.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 1937209
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
All
unloading and container cleaning
Use rate of 100,000 kg/yr. Release from unloading and container clean-
ing
dust to air
0.60 percent
2004 Plastics compounding ESD
200
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
data or techniques that are high quality
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
Canada
Metric 3:
Applicability
High
X
2
2
This data is in scope because the estimation method is from

the 2004 Compounding ESD
Metric 4:
Temporal Representativeness
High
X
2
2
2011
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.2
Continued on next page
97

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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
Environment Canada and Health Canada. 2011. Screening assessment report on hexabromocyclododecane. Chemical Ab-
stracts Service Registry Number 3194-55-6. Ottawa, Canada.
Releases to the Environment; Completed Exposure or Risk Assessments;
1937209

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Environment Canada and Health Canada. 2011. Screening assessment report on hexabromocyclododecane. Chemical Ab-
stracts Service Registry Number 3194-55-6. Ottawa, Canada.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 1937209
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Release or Emission Factor:
Release Estimation Method:
Release Days per Year:
Processing
Compounding of Polystyrene Resin to Produce XPS Masterbatch
Use rate of 100,000 kg/yr. Release from compounding dust
dust to air
0.055 percent
2004 Plastics compounding ESD
200
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
data or techniques that are high quality
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
Canada
Metric 3:
Applicability
High
X
2
2
This data is in scope because the estimation method is from

the 2004 Compounding ESD
Metric 4:
Temporal Representativeness
High
X
2
2
2011
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.2
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
99

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Number of Sites:
Use
XPS Foam
Samples were taked 300-700 meters from a Swedish textile factory that
manufactures XPS treated with HBCD two weeks per year
Water, Air, Land
Air - 1070 ng/m3Soil - 140 to 1,300 ug/kg dry weight
Concentration in the soil and air
1
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Data from trusted source
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Sweden
Metric 3:
Applicability
Unacceptable
x 2
8
Information related to in-scope scenario but not to engineering





assessment
Metric 4:
Temporal Representativeness
Medium
x 2
4
2004
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.4.



Continued on next
page


100

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— continued from previous page
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
101

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Number of Sites:
Disposal
Landfill
Samples of the air, landfill leachate, and sediment were taked
landfill
Water, Air, Land
Air - 0.013 to 0.18 ng/m3 Water - 3 to 9 ng/LSediment - <0.1 ug/kg
dry weight
Concentration in the sediment, water, and air
1
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Data from trusted source
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Sweden
Metric 3:
Applicability
Unacceptable
x 2
8
Information related to in-scope scenario but not to engineering





assessment
Metric 4:
Temporal Representativeness
Medium
x 2
4
2004
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.4.


Continued on next
page


102

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— continued from previous page
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
103

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Number of Sites:
Use
Textile industry
Fish samples were taken up stream and down stream from a Swedish
textile facility. Air samples were take 350 meters from the facility. Sur-
face sediment samples were taked along the river (both upstream and
downstream of the facility)
Water, Air, Land
Air - 0.019 to 0.74 ng/m3 Water - 31 ng/LSediment - <0.1 to 25 ug/kg
dry weightFish - 65 to 1,800 ug/kg dry weightSewage sludge - 30 to 33
ug/kg dry weight
Concentration in the sediment, water, air, and sewage sludge
1
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Data from trusted source
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium	x 1
Unacceptable x 2
Metric 4: Temporal Representativeness Medium	x 2
Metric 5: Sample Size	Low	x 1
2	Sweden
8	Information related to out-of-scope scenario and not to engi-
neering assessment
4 2004
3	characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness	Low	X 1	3 No discussion of variability or uncertainty
Continued on next page
104

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Remberger, M.,Sternbeck, J.,Palm, A.,Kaj, L.,StrA^[mberg, K.,BrorstrA^[m-LundA©n, E.. 2004. The environmental occur-
rence of hexabromocyclododecane in Sweden. Chemosphere.
Type of Data Source Releases to the Environment; Monitoring Data;
Hero ID	1927826
EVALUATION
Domain
Metric
Rating MWF* Score Comments

Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 2.4.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
105

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
High x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Low x 1
2 UK
2 Potentially can be applied to occupational scenario (use of in-
sulation in offices).
2 2013
3 characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Kuo, Y. uY,Zhang, H.,Gerecke, A. C.,Wang, J.. 2014. Chemical Composition of Nanoparticles Released from Thermal Cutting
of Polystyrene Foams and the Associated Isomerization of Hexabromocyclododecane (HBCD) Diastereomers. Aerosol and Air
Quality Research.
Releases to the Environment; Completed Exposure or Risk Assessments;
2674624
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
Processing
EPS Thermal Cutting
From 1 hour long experiments cutting EPS foam
5.2 mg particles containing 160 ug HBCD per hour
measured
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
Switzerland
Metric 3: Applicability
High
X
2
2
Information related to in-scope scenario
Metric 4: Temporal Representativeness
High
X
2
2
2013
Metric 5: Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Kuo, Y. uY,Zhang, H.,Gerecke, A. C.,Wang, J.. 2014. Chemical Composition of Nanoparticles Released from Thermal Cutting
of Polystyrene Foams and the Associated Isomerization of Hexabromocyclododecane (HBCD) Diastereomers. Aerosol and Air
Quality Research.
Releases to the Environment; Completed Exposure or Risk Assessments;
2674624
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
Processing
XPS Thermal Cutting
From 1 hour long experiments cutting XPS foam
4.5 mg particles containing 250 ug HBCD per hour
measured
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Low
X 1
x 2
x 2
x 1
2
2
2
3
UK
Occupational scenario (use of insulation in offices).
2013
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Rauert, C.,Lazarov, B.,Harrad, S.,Covaci, A.,Stranger, M.. 2014. A review of chamber experiments for determining specific
emission rates and investigating migration pathways of flame retardants. Atmospheric Environment.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2343745
EXTRACTION
Parameter Data
Life Cycle Stage: Consumer Use
Life Cycle Description (Subcategory of Use): Insulation in homes
Release Source: Emission test in chamber
Environmental Media: Houses
Release or Emission Factor: 100 ng/g HBCD in dust
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1 2
Unacceptable x 2 8
High x 2 2
Low x 1 3
UK
Non-occupational scenario (in homes). No associated workers.
2013
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.2.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Rauert, C.,Lazarov, B.,Harrad, S.,Covaci, A.,Stranger, M.. 2014. A review of chamber experiments for determining specific
emission rates and investigating migration pathways of flame retardants. Atmospheric Environment.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2343745
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Environmental Media:
Release or Emission Factor:
Consumer Use
Insulation in homes
Emission test in chamber
Near electronic equipment (5 meters from TV)
5,700 to 24,000 ng/g HBCD in dust
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High x 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium x 1 2
Unacceptable x 2 8
High x 2 2
Low x 1 3
UK
Non-occupational scenario (in homes). No associated workers.
2013
characterized by no statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.2.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Kuo, Y. uY,Zhang, H.,Gerecke, A. C.,Wang, J.. 2014. Chemical Composition of Nanoparticles Released from Thermal Cutting
of Polystyrene Foams and the Associated Isomerization of Hexabromocyclododecane (HBCD) Diastereomers. Aerosol and Air
Quality Research.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 2674624
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
Processing
EPS Thermal Cutting
From 1 hour long experiments cutting EPS foam
15 - 40 mg/g for specified particle size range
10 - 1,000 nm (HBCD was the highest concentrations for these size par-
ticles)
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Kuo, Y. uY,Zhang, H.,Gerecke, A. C.,Wang, J.. 2014. Chemical Composition of Nanoparticles Released from Thermal Cutting
of Polystyrene Foams and the Associated Isomerization of Hexabromocyclododecane (HBCD) Diastereomers. Aerosol and Air
Quality Research.
Type of Data Source Releases to the Environment; Completed Exposure or Risk Assessments;
Hero ID 2674624
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
Processing
XPS Thermal Cutting
From 1 hour long experiments cutting XPS foam
20 - 60 mg HBCD/g particle generated, for specified particle size range
10 - 1,000 nm (HBCD was the highest concentrations for these size par-
ticles)
EVALUATION

Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability

Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Ni, H. G.,Lu, S. Y.,Mo, T.,Zeng, H.. 2016. Brominated flame retardant emissions from the open burning of five plastic wastes
and implications for environmental exposure in China. Environmental Pollution.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3350474
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
Number of Sites:
Disposal
Incineration of plastic wastes
Two incineration plants in China
airborne particle (51 percent ), followed by residualash (44 percent ) and
the gas phase (5.1 percent );
air
airborne particle - 26.8 to 5,290 ng HBCD/g plastic wasteresidual ash -
4.9 to 77.1 ng HBCD/g plastic wastegas phase - 10.2 to 17.1 ng HBCD/g
plastic waste
Measured
25.5 kg/yr
2
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Medium
High
High
X 1
x 2
x 2
x 1
3
4
2
1
China
disposal in scope
2016
Statistical distribution of samples is fully characterized.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
data include all associated metadata,
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
114

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— continued from previous page
Source Citation:	Ni, H. G.,Lu, S. Y.,Mo, T.,Zeng, H.. 2016. Brominated flame retardant emissions from the open burning of five plastic wastes
and implications for environmental exposure in China. Environmental Pollution.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3350474
EVALUATION
Domain
Metric
Rating MWF* Score
Comments

Overall Quality Determination^

High 1.4


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
115

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Ni, H. G.,Lu, S. Y.,Mo, T.,Zeng, H.. 2016. Brominated flame retardant emissions from the open burning of five plastic wastes
and implications for environmental exposure in China. Environmental Pollution.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3350474
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
Number of Sites:
Disposal
Incineration of plastic wastes
Two incineration plants in China
airborne particle (51 percent ), followed by residualash (44 percent ) and
the gas phase (5.1 percent );
land
airborne particle - 26.8 to 5,290 ng HBCD/g plastic wasteresidual ash -
4.9 to 77.1 ng HBCD/g plastic wastegas phase - 10.2 to 17.1 ng HBCD/g
plastic waste
Measured
71.7 kg/yr
2
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Medium
High
High
X 1
x 2
x 2
x 1
3
4
2
1
China
disposal in scope
2016
Statistical distribution of samples is fully characterized.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
data include all associated metadata,
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
116

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— continued from previous page
Source Citation:	Ni, H. G.,Lu, S. Y.,Mo, T.,Zeng, H.. 2016. Brominated flame retardant emissions from the open burning of five plastic wastes
and implications for environmental exposure in China. Environmental Pollution.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3350474
EVALUATION
Domain
Metric
Rating MWF* Score
Comments

Overall Quality Determination^

High 1.4


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
117

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3350476
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Manufacturing
HBCD production
All releases were modeled from previous risk assessments, reports, and
China's HBCD industry data
3.30E-07
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Medium
X 1
2
Information compiled from several different sources
Domain 2: Representative





Metric 2:
Geographic Scope
Low
X 1
3
China
Metric 3:
Applicability
Medium
x 2
4
Manufacturing not in scope but maybe can be applied to im-





portation
Metric 4:
Temporal Representativeness
High
x 2
2
2016
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Medium
x 1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

2.1


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
115

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3350476
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Processing
EPS Foam
All releases were modeled from previous risk assessments, reports,
China's HBCD industry data
5.2E-6 to 3.3E-5
and
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 Information compiled from several different sources
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
High
X
2
2
in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

1.9

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3350476
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Processing
XPS Foam
All releases were modeled from previous risk assessments, reports,
China's HBCD industry data
6.9E-6 to 1.7E-5
and
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 Information compiled from several different sources
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
High
X
2
2
in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

1.9

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3350476
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Processing
Textiles
All releases were modeled from previous risk assessments, reports,
China's HBCD industry data
7.0E-6 to 7.3E-6
and
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 Information compiled from several different sources
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
Unacceptable
X
2
8
Out of scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.6.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
121

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Source Citation: Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3350476
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Consumer Use
EPS, XPS, or textiles
All releases were modeled from previous risk assessments, reports,
China's HBCD industry data
5.8E-8 to 1.4E-4
and
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 Information compiled from several different sources
Domain 2: Representative
Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
Unacceptable
X
2
8
Out of scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Medium
X
1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Li, L.,Weber, R.,Liu, J.,Hu, J.. 2016. Long-term emissions of hexabromocyclododecane as a chemical of concern in products
in China. Environment International.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3350476
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Disposal
Demolition, recycling, landfill, or incineration of products containing
HBCD
All releases were modeled from previous risk assessments, reports, and
China's HBCD industry data
1.0E-6 to 9.0E-5
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Medium
X
1
2
Information compiled from several different sources
Domain 2: Representative






Metric 2:
Geographic Scope
Low
X
1
3
China
Metric 3:
Applicability
High
X
2
2
in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
Low
X
1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Medium
X
1
2
Data sources are generally described but not fully transparent.
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium
1.9
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
123

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Source Citation: Takigami, H.,Watanabe, M.,Kajiwara, N.. 2014. Destruction behavior of hexabromocyclododecanes during incineration of
solid waste containing expanded and extruded polystyrene insulation foams. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 2343703
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Waste Treatment Method:
P2 Control & percent Efficiency:
Disposal
EPS and XPS insulation
EPS and XPS materials were respectively blended with refuse derived
fuel (RDF) as input wastes for incineration. Concentrations of HBCDs
contained in the EPS- and XPS-added RDFs, were 140 and 1100 mg kg
1, respectively.
Incineration destruction experiment
During the incineration experiments with EPS and XPS, primary and
secondary combustion zones were maintained at temperatures of 840 C
and 900 C. The residence times of waste in the primary combustion
zone and flue gas in the secondary combustion zone was 30 min and
three seconds, respectively.
Concentration levels of the total HBCDs in the bag filter exit gas for
the two experiments with EPS and XPS were 0.7 and 0.6 ng/m3, re-
spectively. HBCDs were also not detected (<0.2 ng/g) in the bottom
and fly ash samples. From the obtained results, it was calculated that
HBCDs were sufficiently destroyed in the whole incineration process with
destruction efficiencies of more than 99.9999 for both of EPS and XPS
cases.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Japan
Metric 3:
Applicability
High
x 2
2
in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2014
Metric 5:
Sample Size
High
x 1
1
Study contains all sampling data results, from which statistics
can be surmised
Continued on next page
124

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— continued from previous page
Source Citation:	Takigami, H.,Watanabe, M.,Kajiwara, N.. 2014. Destruction behavior of hexabromocyclododecanes during incineration of
solid waste containing expanded and extruded polystyrene insulation foams. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	2343703
EVALUATION




Domain Metric
Rating
MWF*
Score
Comments

Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X 1
1
well characterized
Overall Quality Determination^
High

1.1


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
125

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Stubbings, W. A.,Kajiwara, N.,Takigami, H.,Harrad, S.. 2016. Leaching behaviour of hexabromocyclododecane from treated
curtains. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3162362
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Disposal /Treatment Method:
Release Estimation Method:
Annual Release Quantity (kg/yr):
Disposal
Textiles
HBCD into leachate
landfill
Concentration of HBCD in leachate in which textiles were submerged
was measured over time
310,000 tonnes of textiles are disposed of by householders annually
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
Domain 1: Reliability
Metric 1: Methodology	High	x 1	1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Japan
Metric 3:
Applicability
Unacceptable
X
2
8
Out of scope
Metric 4:
Temporal Representativeness
High
X
2
2
2016
Metric 5:
Sample Size
High
X
1
1
Study contains all sampling data results, from which statistics
can be surmised
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
well characterized
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.8.

Continued on next page
126

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Stubbings, W. A.,Kajiwara, N.,Takigami, H.,Harrad, S.. 2016. Leaching behaviour of hexabromocyclododecane from treated
curtains. Chemosphere.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3162362
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
127

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Guerra, P.,De La Cal, A.,Marsh, G.,Eljarrat, E.,Barcelo, D.. 2009. Transfer of hexabromocyclododecane from industrial
effluents to sediments and biota: Case study in Cinca river (Spain). Journal of Hydrology.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3575325
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Environmental Media:
Release or Emission Factor:
Release Estimation Method:
Processing
EPS resin mfg
surface water
2 ug HBCD/L wastewater effluent
sampled in WW effluent
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
does not cover all release sources at the site
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Spain
Metric 3:
Applicability
Unacceptable
x 2
8
This use is out of scope
Metric 4:
Temporal Representativeness
High
x 2
2
2009
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
x 1
3
includes release media but no other metadata
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.6.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
128

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Oecd,. 2007. SIDS initial assessment profile: Hexabromocyclododecane (HBCDD).
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3809146
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Estimation Method:
Waste Treatment Method:
P2 Control & percent Efficiency:
All
All
EUSES model
wastewater treatment
overall HBCD removal at WWTP of 80 percent ; The major part is
expected to be adsorbed to the sludge
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Medium x 1
The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.
Domain 2: Representative
Metric 2: Geographic Scope
Medium
X
1
2
EU

Metric 3: Applicability
Medium
X
2
4
Information is not from a particular scenario,
but can be ap-





plied to in-scope uses

Metric 4: Temporal Representativeness
Medium
X
2
4
2007

Metric 5: Sample Size
N/A


N/A
This metric is not applicable to this data type.
This figure was





obtained from a model

Domain 3: Accessibility/Clarity






Metric 6: Metadata Completeness
Low
X
1
3
Assessment or report provides results, but
the underlying





methods, data sources, and assumptions are
not fully trans-





parent.

Domain 4: Variability and Uncertainty






Metric 7: Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty

Overall Quality Determination^
Medium


2.2


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
129

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Priddy, D. B.,et al.,. 2000. Kirk-Othmer Encyclopedia of Chemical TechnologyStyrene plastics.
Type of Data Source
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID
3981049
EXTRACTION

Parameter
Data
Life Cycle Stage: All
Life Cycle Description (Subcategory of Use): Styrene Plastics
Release Source: Does not mention HBCD but describes the chemical and physical prop-
erties of styrene plastics in detail.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Unacceptable
X
2
8
Toxicity information is relevant to the Risk Assessment, but is

not utilized by the engineering assessors
Metric 4:
Temporal Representativeness
Low
X
2
6
No Date (earliest sources from 1996)
Metric 5:
Sample Size
N/A

N/A
This metric does not relate to this data type
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
X
1
3
Assessment or report provides results, but the underlying

methods, data sources, and assumptions are not fully trans-

parent.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.8.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
130

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2009. Data on manufacture, import, export, uses and releases of HBCDD as well as information on potential alternatives
to its use.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3809166
EXTRACTION
Parameter Data
Life Cycle Stage: All
Life Cycle Description (Subcategory of Use): All
Release Source: Summarizes releases that are presented in the EURAR (HERO ID
3970747)
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Medium
High
Medium
X
X
X
X
1
2
2
1
2
4
2
2
Multiple European countries
Provides infomration on both in-scope and out of scope uses.
2009
Distribution of samples is characterized by a range with uncer-
tain statistics. It is unclear if analysis is representative.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
fully transparent.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1
1
discussion of variability or uncertainty
Overall Quality Determination^
High

1.4

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Managaki S, Y. Miyake, Y. Yokoyama, H. Hondo, S. Masunaga, S. Nakai, T. Kobayashi, T. Kameya, A. Kimura, T. Nakarai,
Y. Oka, H. Otani, A. Miyake. 2009. Emission Load of Hexabromocyclododecane in Japan Based on the Substance Flow
Analysis. Organohalogen Compounds.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 5079146
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
All
All
Life cycle analysis with releases from multiple stages.
Refer to figure 1
Life cycle analysis
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
The release data methodology is known or expected to be ac-

curate (e.g., trusted source) but not fully explicit
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Japan
Metric 3:
Applicability
High
x 2
2
Contains multiple conditions of use that are in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2009
Metric 5:
Sample Size
Low
x 1
3
Distribution of samples is qualitative or characterized by no
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2
Release data include most critical metadata, including release
media and release frequency, but lacks additional metadata,
such as process, unit operation, and/or activity that is the
source of the release.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
discussion of variability or uncertainty
Overall Quality Determination^
High
1.6

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: L. Morf, A. M. Buser, R. Taverna, H. P. Bader, R. Scheidegger. 2008. Dynamic substance flow analysis as a valuable risk
evaluation tool - A case study for brominated flame retardants as an example of potential endocrine disrupters. Chimia.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 1927966
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Release Source:
Release or Emission Factor:
Release Estimation Method:
All
All
Life cycle analysis with releases from multiple stages.
Refer to figure 4
Life cycle analysis
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Medium X 1 2 The release data methodology is known or expected to be ac-
curate (e.g., trusted source) but not fully explicit
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Sweden
Metric 3:
Applicability
High
X
2
2
Contains multiple conditions of use that are in scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Low
X
1
3
Distribution of samples is qualitative or characterized by no
statistics.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
2
Release data include most critical metadata, including release
media and release frequency, but lacks additional metadata,
such as process, unit operation, and/or activity that is the
source of the release.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
discussion of variability or uncertainty
Overall Quality Determination^
High
1.6

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Occupational Exposure
134

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Source Citation: Thomsen, C.,Molander, P.,Daae, H. L.,JanAjk, K.,Froshaug, M.,Liane, V. H.,Thorud, S.,Becher, G.,Dybing, E.. 2007. Occu-
pational exposure to hexabromocyclododecane at an industrial plant. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 787728
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Exposure Frequency:
Bulk and Dust Particle Size Distribution:
Processing
EPS Resin production
Dust
Inhalation
0.24 ug/m3 - 150 ug/m3 (mean - 12.2 ug/m3; median - 2.1 ug/m3)
30
1
8-hr TWA
24 samples were taken for reactor working procedures and 6 were taken
from mixer working procedures.
10
Personal breathing zone
Reactor (24 samples) or Mixer (6 samples)
8-hr
14 days at a time (7 day periods of no HBCD used in products)
20 nm to 2 mm HBCD particles
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
A certified occupationalhygienist from the company"s Occu-
pationalHealth Service executed the practical air sampling ac-
cordingto a detailed protocol.
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
A Scandanavian Industrial Plant . Since all scandanavian
countries (Sweden, Denmark, Finland, Norway, Iceland) are
in OECD this score is a 2
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may
be applicable to other scenarios that are in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
The report was published in 2007 (> 10 years ago)
Metric 5:
Sample Size
Low
x 1
3
Statistics of the sampling is not discussed.
Continued on next page
135

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— continued from previous page
Source Citation:	Thomsen, C.,Molander, P.,Daae, H. L.,JanAjk, K.,Froshaug, M.,Liane, V. H.,Thorud, S.,Becher, G.,Dybing, E.. 2007. Occu-
pational exposure to hexabromocyclododecane at an industrial plant. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	787728
EVALUATION




Domain Metric
Rating
MWF*
Score
Comments

Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X 1
1
All pertinent monitoring data is provided.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

2.0


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
136

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-

centrations
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
UK
Metric 3:
Applicability
Unacceptable
x 2
8
Non-occupational scenario (settled dust in homes). No associ-

ated worker activites.
Metric 4:
Temporal Representativeness
Medium
x 2
4
Published in 2008 ( 10 years ago)
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations but does not specify number of

samples at each location. However, provides several statistics

of the sample size.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
Specific details of studied samples, sampling and analytical-
protocols, as well as statistical summaries of concentrationsof
individual HBCD in eachsample are available online as well
Domain 4: Variability and Uncertainty
Continued on next page
137

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— continued from previous page
Source Citation:	Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1079114
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
x 1 3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
138

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-

centrations
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
UK
Metric 3:
Applicability
Unacceptable
x 2
8
Occupational scenario (use of insulation in offices). No associ-

ated worker activities.
Metric 4:
Temporal Representativeness
Medium
x 2
4
Published in 2008 ( 10 years ago)
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations but does not specify number of

samples at each location. However, provides several statistics

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1079114
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
x 1 3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
140

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-

centrations
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
UK
Metric 3:
Applicability
Unacceptable
x 2
8
Non-occupational scenario (settled dust in gen pop areas). No

associated worker activites.
Metric 4:
Temporal Representativeness
Medium
x 2
4
Published in 2008 ( 10 years ago)
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations but does not specify number of

samples at each location. However, provides several statistics

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1079114
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
x 1 3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
142

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-

centrations
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
UK
Metric 3:
Applicability
Unacceptable
x 2
8
Non-occupational scenario (outdoor air dust in gen pop areas).

No associated worker activites.
Metric 4:
Temporal Representativeness
Medium
x 2
4
Published in 2008 ( 10 years ago)
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations but does not specify number of

samples at each location. However, provides several statistics

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1079114
EVALUATION
Domain Metric
Rating
MWF* Score
Comments
Metric 7: Metadata Completeness
Low
x 1 3
No discussion of variability or uncertainty
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
144

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1079114
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Consumer Use
Indoor Air
Dust
Inhalation
90 ng/g - 140,000 ng/g (mean - 8,300 ng/g)
97
Concentration in dust
HBCDs found from several products used in indoor environments. No
associated worker activity.
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Medium
x 1
Describes how the data was modeled from the HBCD dust con-
centrations
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope Medium
Applicability Unacceptable
Temporal Representativeness Medium
Sample Size High
x 1 2 UK
X 2 8 Non -occupational scenario (outdoor air dust in gen pop areas).
No associated worker activites.
X 2 4 Published in 2008 ( 10 years ago)
X 1 1 Indicates number of locations but does not specify number of
samples at each location. However, provides several statistics
of the sample size.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness Low X 1 3 Only includes amount in dust (essentially an HBCD concen-
tration)
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low x 1
3
No discussion of variability or uncertainty
Continued on next page
145

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Abdallah, M. A.,Harrad, S.,Covaci, A.. 2008. Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust
in Birmingham, U.K: implications for human exposure. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1079114
EVALUATION
Domain
Metric
Rating MWF* Score Comments

Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 2.6.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
146

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Source Citation:
ToxNet Hazardous Substances Data, Bank. 2017. HSDB: Hexabromocyclododecane.
Type of Data Source
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID
3970277
EXTRACTION

Parameter
Data
Life Cycle Stage:	Import
Life Cycle Description (Subcategory of Use):	Import
Worker Activity:	Workers at importation and manufacturing sites per 2012 CDR
Number of Workers:	<10 to 25-49 workers per site
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
High
High
Medium
X
X
X
X
1
2
2
1
1
2
2
2
US
Importation is in scope
2012
Information is from 3 CDR reporting sites, which represents
only the sites exceeding the reporting threshold, so maybe not
every possible site
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
X
1
2
Report addresses CBI claims, but not much else
Overall Quality Determination^
High


1.2

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
147

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Source Citation: Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID 3978355
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Commerical Use
Insulation products in Offices
settled dust
Inhalation
Mean = 1400 ug/kg dust, Median = 650 ug/kg dust (UK); Mean = 592
ug/kg dust, Median = 367 ug/kg dust (Belgium)
16
Unknown (>10)
HBCD concentration in dust was measured and exposure was calculated
with assumptions. See assumptions on page 59.
Office workers. No associated worker activity.
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology High X 1 1 Information collected from journal studies
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
UK, Belgium
Metric 3:
Applicability
Unacceptable
X
2
8
Occupational scenario (use of insulation in offices). No associ-
ated worker activities.
Metric 4:
Temporal Representativeness
High
X
2
2
2008-2010
Metric 5:
Sample Size
Medium
X
1
2
Mean and median provided, no other statistics. 16 samples,
unknown # of sites
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness Medium X 1 2 Limited discussion on uncertainty and variability
Continued on next page
148

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
Overall Quality Determination^	Unacceptable	4 Metric Mean Score: 2.0.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
149

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Import
Import
Dust
Inhalation
0.20.5 mg/m3 (typical); 0.55 mg/m3 (worst case)
Modelled (section 6.4)
repackaging into smaller pack sizes or in the event of an accident or spill
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
High
x 1
1
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^
High
1.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
150

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Import
Import
Dust
Dermal
57570 ?g/kg bw/d (powder); 29290 ?g/kg bw/d (granules)
Modelled (section 6.4)
repackaging into smaller pack sizes or in the event of an accident or spill
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
High
x 1
1
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^
High
1.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
151

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Type of Measurement or Method:
Worker Activity:
Number of Workers:
Exposure Duration:
Exposure Frequency:
Bulk and Dust Particle Size Distribution:
Engineering Control & percent Exposure Reduction:
PPE:
Processing
EPS compounding
Dust
respondents from survey
Adding HBCD to the mixture
1
10 min/day
180 days/yr
2	mm granules or 50-60 um powder
LEV
Overalls, safety glasses, leather or chemical resistant gloves, dust masks
and respirators
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information collected from surevey respondents
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may





be applicable to other scenarios that are in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Medium
x 1
2
Results from 1 respndent
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion

Continued on next page
152

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	Medium	1.7
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
153

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
EPS compounding
Dust
Inhalation
2.89-21.5 mg/m3
12
2
Short-term
Adding HBCD powder to the mixture
personal
13-56 mins
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from a study in Scotland
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Scotland
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may





be applicable to other scenarios that are in scope or may be





used as surrogate data
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and





seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
Uncertainty and variability discussion provided


Continued on next
page

154

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
155

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
EPS compounding
Dust
Inhalation
0.12-3.36 mg/m3
12
2
8 hr TWA
Adding HBCD powder to the mixture
personal
480 mins
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from a study in Scotland
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Scotland
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may





be applicable to other scenarios that are in scope or may be





used as surrogate data
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and





seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
Uncertainty and variability discussion provided


Continued on next
page

156

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
157

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
EPS compounding
Dust
Inhalation
0.07-14.7 mg/m3
18
3
full-shift
Adding HBCD powder to the mixture
personal
275-504 mins
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from a study in Scotland
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Scotland
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may





be applicable to other scenarios that are in scope or may be





used as surrogate data
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and





seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
Uncertainty and variability discussion provided


Continued on next
page

158

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
159

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
EPS compounding
Dust
Inhalation
4.35-12.1 mg/m3
4
2
full-shift
Weighing HBCD powder before addition
personal
124-350 mins
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from a study in Scotland
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Scotland
Metric 3:
Applicability
Medium
x 2
4
Manufacturing EPS is not in scope, but some information may





be applicable to other scenarios that are in scope or may be





used as surrogate data
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and





seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
Uncertainty and variability discussion provided


Continued on next
page

160

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.6
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
161

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Occupational Exposure; Completed Exposure or Risk Assessments;
3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Exposure Duration:
Processing
XPS production
Dust
Inhalation
2-880 ug/m3
17
6
full-shift
area sampling at feed deck
area
feed deck
4.4-23.9 hours
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x
1 2
Limited discussion on uncertainty


Continued on next
page

162

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
163

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS production
Dust
Inhalation
3-15 ug/m3
9
6
Short-term
routine work
personal
3-7.3 hrs
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and
seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 Limited discussion on uncertainty
Overall Quality Determination^
High
1.4
Continued on next page

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
165

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS production
Dust
Inhalation
40 ug/m3
6
6
Short-term
cleaning feed deck
personal
1 hr
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and
seems sufficient
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1 Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2 Limited discussion on uncertainty
Overall Quality Determination^
High
1.4
Continued on next page
166

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
167

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Occupational Exposure; Completed Exposure or Risk Assessments;
3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Processing
EPS converting
Dust
Inhalation
Mean = 0.5 ug/m3
6
1
full-shift
3/shift
area
mixer room
8 hr
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Norway
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2007
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
Uncertainty and variability discussion provided


Continued on next
page

168

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
169

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Occupational Exposure; Completed Exposure or Risk Assessments;
3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Processing
EPS converting
Dust
Inhalation
Mean = 15.1 ug/m3
24
1
Type of Measurement or Method:
full-shift



Number of Workers:

3/shift



Type of Sampling:

area



Sampling Location:

reactor room


Exposure Duration:

8 hr



EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Results extracted from journal article
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Norway
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2007
Metric 5:
Sample Size
High
x 1
1
Statistical distribution provided; Sample size provided and





seems sufficient
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided

Continued on next page
170

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— continued from previous page
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
171

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Processing
XPS compounding
Dust
dermal
0.11 mg/cm2/d.
Modelled (section 6.5)
direct handling and intermittent, non-dispersive use
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
High
x 1
1
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^
High
1.1
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
172

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Exposure Duration:
Processing
Polymer processing
Dust
Inhalation
Typical: 2 to 5Worst-case: 5 to 50 mg/m3
Modelled (section 6.5)
addition and weighing
8 hr
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
High
x 1
1
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^
High
1.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
173

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Exposure Duration:
Processing
Polymer processing
Granules
Inhalation
Typical: 0.2 to 0.5Worst-case: 0.5 to 5
Modelled (section 6.5)
addition and weighing
8 hr
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Australia
Metric 3:
Applicability
High
x 2
2
Use in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
High
x 1
1
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^
High
1.1
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
174

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Nicnas,. 2012. Priority existing chemical assessments: Hyexabromocyclododecane (HBCD)- PEC34.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3978355
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
All
HBCD in dust
Dust
Oral to dust
1.9 (typical) to 12 (worst case) ng/kg-day
Modelled (section 6.5.5)
Exposure to HBCD in indoor soil and dust
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Based on accepted model from Europe
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Low
Medium
High
X 1
x 2
x 2
x 1
2
6
4
1
Australia
Non-occupational exposure that can be applied to occupational
2003
Model - uncertainty provided, distribution of results provided
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
Uncertainty and variability discussion provided
Overall Quality Determination^	Medium	1.8
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
175

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Source Citation: Haz, Map. 2017. Haz-Map: Agent name: 1,2,5,6,9,10-Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3970257
EXTRACTION
Parameter

Data

Life Cycle Stage:
Worker Activity:
Number of Workers:

All
worker esitmate
100 to 999
across
entire lifecycle
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
X 1
3
Unknown
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
High
Medium
High
Low
X 1
x 2
x 2
x 1
1
4
2
3
US
Captures all possible stages, some of which are not in scope
2016
Unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable
x 1
4
Unknown
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
x 1
3
No discussion
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 2.2.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Manufacture
Manufacture
dust
Inhalation
0.00028 - 0.0285 mg/m3
3
1
short-term, 51-120 mins
Occasional sampling at the reactor. Worker activity may or may not be
occurring during the measurement.
area
reactor
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Unacceptable
x 2
8
Manufacture is not in scope and data cannot be applied to





other conditions of use
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
High
x 1
1
All data points provided
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the





results. Uncertainty is well characterized.


Continued on next
page


177

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
Overall Quality Determination^	Unacceptable	4 Metric Mean Score: 1.8.
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
178

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Manufacture
Manufacture
dust
Inhalation
0.0094-0.097 mg/m3
2
1
short-term, 88 mins
Worker Activity:

filling of 25 kg or 1 ton bags
Type of Sampling:

area


Exposure Duration:

88 mins


Bulk and Dust Particle Size Distribution:
20-150 ?m


EVALUATION




Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability




Metric 1:
Methodology
High
X 1 1
Information is from trusted sources
Domain 2: Representative




Metric 2:
Geographic Scope
Medium
x 1 2
Europe
Metric 3:
Applicability
Medium
x 2 4
Manufacture is not in scope but filling of bags can be applied




to Import
Metric 4:
Temporal Representativeness
High
x 2 2
2008
Metric 5:
Sample Size
High
x 1 1
All data points provided
Domain 3: Accessibility/Clarity



Metric 6:
Metadata Completeness
High
x 1 1
Assessment or report clearly documents its data sources, as-




sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
179

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
Overall Quality Determination^	High	1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
180

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
4.0-4.5 mg/m3
unknown
unknown
Bagging HBCD product
unknown
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2 Range
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High


1.4


Continued on next
page


181

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— continued from previous page
Source Citation:
Echa,. 2008. Risk assessment: hexabromocyclododecane.

Type of Data Source
Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID
3970747

EVALUATION


Domain
Metric Rating MWF* Score
Comments

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
Mean: 1.23Median: 0.8990th percentile: 1.89Max: 3 mg/m3
10
1
8-hr TWA
During sample measurement, worker activity may include packing, com-
pactation, process operations, and working in the warehouse
personal
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Manufacture is not in scope but operations can be applied to






Import
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-






sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the






results. Uncertainty is well characterized.
Continued on next page
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— continued from previous page

Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
Mean: 23 90th percentile: 35 mg/m3
4
1
8-hr TWA
Not specified. Worker activity may include several different tasks,
personal
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Unacceptable
x 2
8
Manufacture is not in scope and data cannot be applied to





other conditions of use due to uncertainties
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5: Sample Size
Medium
x 1
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.9.

Continued on next
page


185

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
186

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
1.9 mg/m3
1
1
300 min
Transfer of the HBCD in the hammer-mill to 28 drums
personal
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
Manufacture is not in scope but operations can be applied to





Import
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5: Sample Size
High
x 1
Discrete data point provided
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3


Continued on next
page


187

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
188

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
Respirable, Mean: 0.18Inhalable, Mean: 1.23 mg/m3
unknown
unknown
unknown
packing and compaction of powders
unknown
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
Medium
High
Medium
XX XX
1
2
2
1
2
4
2
2
Europe
Manufacture is not in scope but operations can be applied to
Import
2008
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High


1.4


Continued on next
page


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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
190

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Manufacture
Manufacture
dust
Inhalation
0.0102 - 0.0283 mg/m3
14
unknown
unknown
Weighing and mixing
personal
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Manufacture is not in scope but operations can be applied to
Import
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


Continued on next
page


191

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
192

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture
Manufacture
dust
Dermal
1 to 5 mg/cm2/day
Modelled by EASE
filling of 25 kg or 1 ton bags
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Manufacture is not in scope but filling of bags can be applied






to Import
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
characterized by a range uncertain statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-






sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the






results. Uncertainty is well characterized.
Overall Quality Determination^
High
1.4
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
193

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
granule
Inhalation
Max 7.5 (for 2 hours)Mean: 1.89Median: 0.8390th percentile: 5.4 mg
m3
10
short-term
mixing and weighing
area
Measurements range from 19 to 295 minutes.
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
Medium
x 1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.


Continued on next
page

194

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— continued from previous page

Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
granule
Inhalation
0.88 (mean), 1.36 (90th) mg/m3
10
8-hr TWA
mixing and weighing
personal
19-295 min
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
Medium
X
2
4
2005
Metric 5:
Sample Size
Medium
X
1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
197

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
granule
Inhalation
Mean: 0.12Median: 0.100.16 mg/m3 (90th)
4
unknown
extruder operator
personal
5	hours
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
Medium
X
2
4
2005
Metric 5:
Sample Size
Medium
X
1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
199

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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
unknown
Inhalation
negligible
3
1
unknown
Automated handling of HBCD
unknown
unknown
EVALUATION
Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
Low
X 1
x 2
x 2
x 1
2
2
4
3
Europe
In scope
2005
Qualitative
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.6

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
powder
Inhalation
ND to 1.6 mg/m3
16
2
unknown
unknown
area
40-480 min
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
Medium
x 1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.


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page

202

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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
203

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
powder
Inhalation
Range: 0.0002-0.0009Mean: 0.0005 Median: 0.0005 mg/m3
30
unknown
mixer operator
personal
8-hr
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
Medium
X
2
4
2007
Metric 5:
Sample Size
Medium
X
1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
205

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
granules
Inhalation
Range 0.005-0.9Mean: 0.2490th percentile: 0.47(excluding 16 ND sam-
ples)
43 (16 ND)
varies, 60 -2435 minutes
Feed deck near typical operator positions
Mostly area and some personal breathing zone
60 1435 minutes
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
Medium
x 1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.


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page

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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
207

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Processing
XPS masterbatch
granules
Inhalation
Mean: 0.0000390th percentile: 0.00004
12
Type of Measurement or Method:
8-hr TWA



Worker Activity:

Logistics, extruding, and laboratory
Type of Sampling:

Area



Exposure Duration:

8-hr TWA



EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Norway
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2005
Metric 5:
Sample Size
Medium
x 1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
209

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
Manufacture of EPS resin beads
Respirable Dustlnhalable Dust
Inhalation
Respirable dust: <0.5 Total Inhalable dust: 2.0 mg/m3Not specific to
HBCD
5
8-hr TWA
Addition of HBCDD to reactor or the supervising of the addition.
personal
8-hr TWA
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
Condition of use is out of scope, but data may be applicable





to other conditions of use
Metric 4:
Temporal Representativeness
Medium
x 2
4
Original data from 1999
Metric 5:
Sample Size
Medium
x 1
2
Some statistics provided, others unknown
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-





sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ Medium 1.7

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
granule
Inhalation
ND to 0.88 mg/m3
32
6
unknown
unknown
area and personal
40-1435 min
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
High
x 2
2
In scope
Metric 4:
Temporal Representativeness
Medium
x 2
4
2001
Metric 5:
Sample Size
Medium
x 1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
1 1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.


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page

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Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747

EVALUATION
Domain
Metric Rating MWF* Score
Comments
Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
213

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Processing
cutting of XPS boards
solid
Inhalation
0.22 mg/m3 (90th)
42
3
unknown
unknown
area?
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
Medium
X
2
4
2005
Metric 5:
Sample Size
Medium
X
1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
215

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Exposure Duration:
Processing
XPS masterbatch
powder
Inhalation
mean 15 ?g/m3, median 2.7 ?g/m3
30
unknown
reactor operator
personal
8-hr
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Norway
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
Medium
X
2
4
2007
Metric 5:
Sample Size
Medium
X
1
2
unknown if TWA, unknown worker activities
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x
1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x
1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.4


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page


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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
217

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
PPE:
Processing
EPS Resin production
powder
Inhalation
Mean: 1.290 percent -ile: 1.1 mg/m3
8-hr TWA
adding to vessel
personal
Most workers were reported to use gloves,
disposable respirator.
overall, eye protection, and
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2:
Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope	Medium	x 1	2
Applicability	Medium	x 2	4
Temporal Representativeness	Medium	x 2	4
Sample Size	High	x 1	1
Europe
Manufacturing EPS is not in scope, but some information may
be applicable to other scenarios that are in scope
2005
Fully characterized
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High 1.6

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
219

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Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
PPE:
Processing
EPS Resin production
powder
Inhalation
Mean: 7.290 percent -ile: 10.6 mg/m3
8-hr TWA
Weighing HBCD powder before addition
personal
Most workers were reported to use gloves,
disposable respirator.
overall, eye protection, and
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
x 1
Information is from trusted sources
Domain 2:
Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope	Medium	x 1	2
Applicability	Medium	x 2	4
Temporal Representativeness	Medium	x 2	4
Sample Size	High	x 1	1
Europe
Manufacturing EPS is not in scope, but some information may
be applicable to other scenarios that are in scope
2005
Fully characterized
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High 1.6

Continued on next page
220

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— continued from previous page
Source Citation:	Echa,. 2008. Risk assessment: hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970747
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
221

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Echa,. 2008. Risk assessment: hexabromocyclododecane.
Occupational Exposure; Completed Exposure or Risk Assessments;
3970747
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Processing
XPS compounding
powder
Dermal
0-0.1 mg/cm2/day
Modelled by EASE
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
characterized by a range uncertain statistics
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

Parameter

Data

Life Cycle Stage:

All

Number of Workers:

<2100

EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative

Metric 2:
Geographic Scope
High
X 1
1
US
Metric 3:
Applicability
Medium
x 2
4
Captures releases from all possible stages, some of which are

not in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Medium
x 1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High

1.3

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture or Processing
Manufacture, Processing EPS or XPS
dust
Inhalation
0.1 to 2.5 mg/m3
taken from 2008 EU assessment (HERO 3970747)
handling standard grade HBCD powder at sites for the manufacture or
processing
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
x 1
Sampling or analytical methodology is not specified.
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Medium x 1
Europe
EPS compounding and MFG not in scope, but other scenarios
are
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
Monitoring data include most critical metadata, such as sample
type and exposure type, but lacks additional metadata, such
as sample durations, exposure durations, exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Medium
1.8
Continued on next page
224

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— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
225

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3809277
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture or Processing
Manufacture, Processing EPS or XPS
solid
Dermal
84 to 840 mg/day
taken from 2008 EU assessment (HERO 3970747)
handling standard grade HBCD powder at sites for the manufacture or
processing
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Domain 1: Reliability
Metric 1: Methodology
Low
x 1
Sampling or analytical methodology is not specified.
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size Medium x 1
Europe
EPS compounding and MFG not in scope, but other scenarios
are
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Medium x 1
Monitoring data include most critical metadata, such as sample
type and exposure type, but lacks additional metadata, such
as sample durations, exposure durations, exposure frequency
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Medium
1.8
Continued on next page
226

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	U.S, E. P. A.. 2015. TSCA Work Plan chemical problem formulation and initial assessment. Cyclic aliphatic bromide cluster
flame retardants.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3809277
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
227

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
Fine powder (via micronisation)
Inhalation
Worst case = 10 mg/m3; typical = 5 mg/m3
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
228

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
Fine powder (via micronisation)
Dermal
4200 mg/day
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
229

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
powder
Inhalation
Worst case = 1.9 mg/m3; typical = 0.95 mg/m3
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
230

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
granule
Inhalation
Worst case = 0.19 mg/m3; typical = 0.1 mg/m3
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
231

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
powder
Dermal
840 mg/day
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
232

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Manufacture
Manufacture
granule
Dermal
84 mg/day
from monitoring data or modelled
Filling of bags at the production of HBCDD
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION



Domain
Metric
Rating
MWF* Score Comments
Domain 1: Reliability



Metric 1:
Methodology
High
X 1 1 Information is from trusted sources
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Medium x 2
Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1
2 Europe
4	Manufacture is not in scope but filling of bags can be applied
to Import
2 2008
2	characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
High
1.6


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
233

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
Fine powder (via micronisation)
Inhalation
Worst case = 3.1 mg/m3; typical = 1.55 mg/m3
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
234

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
Fine powder (via micronisation)
Dermal
120 mg/day
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
235

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
powder
Inhalation
Worst case = 2.5 mg/m3; typical = 1.25 mg/m3
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
236

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
granule
Inhalation
Worst case = 0.22 mg/m3; typical = 0.11 mg/m3
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
237

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
powder
Dermal
84 mg/day
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
238

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	2008. Summary risk assessment report: Hexabromocyclododecane.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	3970756
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Bulk and Dust Particle Size Distribution:
Processing
Formulation of XPS
granule
Dermal
8.4 mg/day
from monitoring data or modelled
Adding HBCD to process
micronised typically 3 to 4 ?m, powder typically 50 to 250 ?m; granulates
typically > 500 ?m
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
High
Medium
X 1
x 2
x 2
x 1
2
2
2
2
Europe
In scope
2008
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
High
1.3
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
239

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture
Manufacture
powder
Inhalation
0.18 mg/m3 of HBCD in dust (respirable); 1.23 mg/m3 HBCD in dust
(total)
measured
Packaging of powders
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Low
X
1
3
Sampling or analytical methodology is not specified.
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
Manufacture is not in scope but filling of bags can be applied






to Import
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Unacceptable
X
1
4
Monitoring data do not include any needed metadata to un-






derstand what the data represent and are not usable in the risk






evaluation
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Medium
X
1
2
limited discussion
Overall Quality Determination^
Unacceptable


4
Metric Mean Score: 2.1.
Continued on next page
240

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Occupational Exposure; Monitoring Data;
3970759

EVALUATION
Domain
Metric Rating MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
241

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970759
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture
Manufacture
powder
Dermal
170 mg/day
modelled with EASE
Packaging of powders
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
approved modelling approach
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
Manufacture is not in scope but filling of bags can be applied





to Import
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
Medium
x 1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Low
x 1
3
Enough metadata to be used
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
Medium

1.8


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
242

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970759
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Manufacture
Manufacture
granule
Dermal
17 mg/day
modelled with EASE
Packaging of powders
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
approved modelling approach
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
Manufacture is not in scope but filling of bags can be applied





to Import
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
Medium
x 1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Low
x 1
3
Enough metadata to be used
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
Medium

1.8


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
243

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3970759
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Processing
XPS formulation
Dust
Inhalation
mean 0.01 mg/m3 (respirable), 0.03 mg/m3 (total)
measured
EVALUATION
Domain Metric Rating MWF* Score Comments
Domain 1: Reliability
Metric 1: Methodology Low X 1 3 Sampling or analytical methodology is not specified.
Domain 2: Representative
Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
High
X
2
2
In scope
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Unacceptable x 1
4
Monitoring data do not include any needed metadata to un-
derstand what the data represent and are not usable in the risk
evaluation
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.9.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970759
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Processing
EPS, HIPS, production of textile coating
Dust
Inhalation
mean total dust 1.18 to 1.89 mg/m3
measured
EVALUATION






Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability






Metric 1:
Methodology
Low
X
1
3
Sampling or analytical methodology is not specified.
Domain 2: Representative






Metric 2:
Geographic Scope
Medium
X
1
2
Europe
Metric 3:
Applicability
Medium
X
2
4
These compounding processes are not in scope but may provide






baseline for other scenarios
Metric 4:
Temporal Representativeness
High
X
2
2
2008
Metric 5:
Sample Size
Medium
X
1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity





Metric 6:
Metadata Completeness
Unacceptable
X
1
4
Monitoring data do not include any needed metadata to un-






derstand what the data represent and are not usable in the risk






evaluation
Domain 4: Variability and Uncertainty





Metric 7:
Metadata Completeness
Medium
X
1
2
limited discussion
Overall Quality Determination^
Unacceptable


4
Metric Mean Score: 2.1.
Continued on next page
245

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Occupational Exposure; Monitoring Data;
3970759

EVALUATION
Domain
Metric Rating MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
246

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Echa,. 2009. Prioritisation and Annex XIV background information: hexbromocyclododecane.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	3970759
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Processing
HBCDD use for XPS, EPS andHIPS
Solid
Dermal
17 mg/day
modelled
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
approved modelling approach
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Europe
Metric 3:
Applicability
Medium
x 2
4
XPS in scope but others are not
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
Medium
x 1
2
characterized by a range with uncertain statistics
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
Low
x 1
3
Enough metadata to be used
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Medium
x 1
2
limited discussion
Overall Quality Determination^
Medium
1.8
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
247

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927552
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Bulk and Dust Particle Size Distribution:
Commerical Use
Insulation products in offices
dust captured on indoor air filters
Inhalation
27.3 - 2,274 pg/m3 (mean - 1,001 pg/m3)
56 (1 per site)
56
TWA
Modeled data based on HBCD concentration in dust. No associated
worker activity.
Cenral air conditioner filter dusts were collected as particulate phase of
indoor air (PPIA)
Offices
PM2.5 (Paricle Size 0.4 - 2.2 um)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-





centrations
Domain 2: Representative





Metric 2:
Geographic Scope
Low
X 1
3
China (non-OECD country)
Metric 3:
Applicability
Low
x 2
6
The data are for a non-occupational scenario (consumer expo-





sure) that is similar to an occupational scenario (service life)





within the scope of the risk evaluation
Metric 4:
Temporal Representativeness
High
x 2
2
2013
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations and provides several statistics of





the sample size.
Domain 3: Accessibility/Clarity
Continued on next page
248

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927552
EVALUATION




Domain Metric
Rating
MWF*
Score
Comments
Metric 6: Metadata Completeness
High
X 1
1
Monitoring data include all associated metadata.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

2.0


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
249

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927552
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Sampling Location:
Bulk and Dust Particle Size Distribution:
Commerical Use
Insulation products in offices
dust captured on indoor air filters
Inhalation
13.5 - 1,099 pg/m3 (mean - 235 pg/m3)
56 (1 per site)
56
TWA
Modeled data based on HBCD concentration in dust
Cenral air conditioner filter dusts were collected as particulate phase of
indoor air (PPIA)
Offices
PM10 (Paricle Size 2.5 - 8.9 um)
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
Medium
X 1
2
Describes how the data was modeled from the HBCD dust con-





centrations
Domain 2: Representative





Metric 2:
Geographic Scope
Low
X 1
3
China (non-OECD country)
Metric 3:
Applicability
Low
x 2
6
The data are for a non-occupational scenario (consumer expo-





sure) that is similar to an occupational scenario (service life)





within the scope of the risk evaluation
Metric 4:
Temporal Representativeness
High
x 2
2
2013
Metric 5:
Sample Size
High
x 1
1
Indicates number of locations and provides several statistics of





the sample size.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Monitoring data include all associated metadata.
Continued on next page
250

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927552
EVALUATION


Domain Metric
Rating
MWF* Score Comments

Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X 1 3 No discussion of variability or uncertainty
Overall Quality Determination^
Medium
2.0

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
251

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Occupational Exposure; Monitoring Data;
1927552
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Sites:
Type of Measurement or Method:
Worker Activity:
Consumer Use
Insulation products in indoor public microenvironments
settled dust
Inhalation
90 ng/g - 140,000 ng/g (mean - 8,300 ng/g)
97
Concentration in dust
HBCDs found from several products used in indoor environments. No
associated worker activity.
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
Low
x 1 3
Does not specify releases since mostly measure dust concentra-
tion for exposure modeling
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Medium x 1
Low x 2
Metric 4: Temporal Representativeness Medium x 2
Metric 5: Sample Size High x 1
2 UK
6 The data are for a non-occupational scenario (consumer expo-
sure) that is similar to an occupational scenario (service life)
within the scope of the risk evaluation
4 Published in 2008 ( 10 years ago)
1 Indicates number of locations but does not specify number of
samples at each location. However, provides several statistics
of the sample size.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
Low
X
1 3
Release data include release media but no other metadata.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Low
X
1 3
No discussion of variability or uncertainty

Continued on next
page

252

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Ni, H. G.,Zeng, H.. 2013. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927552
EVALUATION
Domain
Metric
Rating MWF* Score
Comments

Overall Quality Determination^

Low 2.4


* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
253

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X
1
3
Does not specify releases, only dust concentrations
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Low
X
2
6
The data are for a non-occupational scenario (consumer expo-

sure) that is similar to an occupational scenario (service life)

within the scope of the risk evaluation
Metric 4:
Temporal Representativeness
High
X
2
2
Samples were collected in 2010
Metric 5:
Sample Size
Medium
X
1
2
Provides number of samples but little statistical bases
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
Low
X
1
3
Only includes amount in dust (essentially an HBCD concen-

tration)
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

2.2

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page

254

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— continued from previous page
Source Citation:	Allen, J. G.,Stapleton, H. M.,Vallarino, J.,McNeely, E.,McClean, M. D.,Harrad, S. J.,Rauert, C. B.,Spengler, J. D.. 2013.
Exposure to flame retardant chemicals on commercial airplanes. Environmental Health: A Global Access Science Source.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1597662
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
255

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
Low
X
1
3
Does not specify releases, only dust concentrations
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
US
Metric 3:
Applicability
Low
X
2
6
The data are for a non-occupational scenario (consumer expo-

sure) that is similar to an occupational scenario (service life)

Metric 6:
Metadata Completeness
Low
X
1
3
Only includes amount in dust (essentially an HBCD concen-

tration)
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
Low
X
1
3
No discussion of variability or uncertainty
Overall Quality Determination^
Medium

2.2

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page

256

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Allen, J. G.,Stapleton, H. M.,Vallarino, J.,McNeely, E.,McClean, M. D.,Harrad, S. J.,Rauert, C. B.,Spengler, J. D.. 2013.
Exposure to flame retardant chemicals on commercial airplanes. Environmental Health: A Global Access Science Source.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1597662
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
257

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Harrad, S.,Ibarra, C.,Abdallah, M. A. E.,Boon, R.,Neels, H.,Covaci, A.. 2008. Concentrations of brominated flame retardants
in dust from United Kingdom cars, homes, and offices: causes of variability and implications for human exposure. Environment
International.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID I005I48
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Commerical Use
Insulation products in offices
settled dust
Inhalation
31,000 ?PBDEs/g
Concentration in dust
Average concentrations of polybrominated diphenyl ethers (PBDEs) in
dust in 18 offices. No associated worker activities.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain f: Reliability

Metric f:
Methodology
High
X f
f
Methodology is well described
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X f
2
UK
Metric 3:
Applicability
Low
x 2
6
The data are for a non-occupational scenario (consumer expo-

sure) that is similar to an occupational scenario (service life)

within the scope of the risk evaluation
Metric 4:
Temporal Representativeness
High
x 2
2
2008
Metric 5:
Sample Size
High
x f
f
Indicates number of locations and provides several statistics of

the sample size.
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
X
f f
Include necessary metadata
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
X
f f
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Continued on next
page

258

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— continued from previous page
Source Citation:	Harrad, S.,Ibarra, C.,Abdallah, M. A. E.,Boon, R.,Neels, H.,Covaci, A.. 2008. Concentrations of brominated flame retardants
in dust from United Kingdom cars, homes, and offices: causes of variability and implications for human exposure. Environment
International.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	I005I48
EVALUATION
Domain
Metric
Rating MWF* Score
Comments
Overall Quality Determination^

High 1.6


* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
259

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:
Type of Data Source
Hero ID
Nicnas,. 2001. Polybrominated flame retardants (PBFRs): Priority existing chemical assessment report no. 20.
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
1443962
EXTRACTION
Parameter
Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Worker Activity:
Processing
Formulation of XPS and converting of XPS
Workers in the formulation industry, that is those involved in the formu-
lation of flame retarded resins, have the greatest risk of exposure since
they weigh, transfer and mix the solid powder or liquid resins contain-
ing pure/concentrated PBFRs. Downstream fabricators who handle the
formulated resins, emulsions and/or polymers are also expected to be
exposed to the PBFRs. Dermal contact is the main route of exposure
resulting from contact with these solutions. Given that the PBFRs are
non-volatile, exposure by inhalation is expected to be minimal when
handling liquid resins. However, potential for exposure by inhalation of
dust generated while handling powder compounds is high. Some release
of volatile, thermal degradation products of some PBFRs may occur
during moulding of polymer at processing temperatures.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Information from trusted sources
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Medium
High
Medium
N/A
X 1
x 2
x 2
2
2
4
N/A
Australia
In-scope
2001
This metric is not applicable to this data type
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Continued on next page
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— continued from previous page
Source Citation:
Type of Data Source
Hero ID
Nicnas,. 2001. Polybrominated flame retardants (PBFRs): Priority existing chemical assessment report no. 20.
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
1443962
EVALUATION
Domain
Metric
Rating MWF* Score Comments

Metric 7; Metadata Completeness
High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
High 1.4

* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Allen, J. G.,Stapleton, H. M.,Vallarino, J.,McNeely, E.,McClean, M. D.,Harrad, S. J.,Rauert, C. B.,Spengler, J. D.. 2013.
Exposure to flame retardant chemicals on commercial airplanes. Environmental Health: A Global Access Science Source.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1597662
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Type of Measurement or Method:
Worker Activity:
Consumer Use
Insulation products in homes
settled dust
Inhalation
6 - 2000 ng HBCD/g dust
Concentration in dust
Average concentrations of HBCD in homes. No associated worker activ-
ity.
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
x 1
Methodology is well described
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope High x 1
Applicability Unacceptable x 2
Temporal Representativeness High x 2
Sample Size High x 1
1 US
8 Non -occupational scenario (settled dust in homes). No associ-
ated worker activites.
2 2017
1 Indicates number of locations and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.7.
Continued on next page
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Allen, J. G.,Stapleton, H. M.,Vallarino, J.,McNeely, E.,McClean, M. D.,Harrad, S. J.,Rauert, C. B.,Spengler, J. D.. 2013.
Exposure to flame retardant chemicals on commercial airplanes. Environmental Health: A Global Access Science Source.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1597662
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
263

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	1927576
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Processing
XPS Thermal Cutting
Dust
Inhalation
89.0 ug/m3
Modeled personal area breathing zone based on closed glovebox sampling
system
1
personal
Thermal cutting operation
1 hour
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Switzerland
Metric 3:
Applicability
High
x 2
2
in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

Continued on next page
264

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	1927576
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
265

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	1927576
EXTRACTION
Parameter	Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Worker Activity:
Number of Workers:
Type of Sampling:
Sampling Location:
Exposure Duration:
Processing
EPS Thermal Cutting
Dust
Inhalation
57.3 ug/m3
Modeled personal area breathing zone based on closed glovebox sampling
system
1
personal
Thermal cutting operation
1 hour
EVALUATION





Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability





Metric 1:
Methodology
High
X 1
1
Information is from trusted sources
Domain 2: Representative





Metric 2:
Geographic Scope
Medium
X 1
2
Switzerland
Metric 3:
Applicability
High
x 2
2
in scope
Metric 4:
Temporal Representativeness
High
x 2
2
2012
Metric 5:
Sample Size
Low
x 1
3
characterized by no statistics.
Domain 3: Accessibility/Clarity




Metric 6:
Metadata Completeness
High
x 1
1
Information is all clearly cited
Domain 4: Variability and Uncertainty




Metric 7:
Metadata Completeness
Low
x 1
3
No discussion of variability or uncertainty
Overall Quality Determination^
High

1.6

Continued on next page
266

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Zhang, H.,Kuo, Y. Y.,Gerecke, A. C.,Wang, J.. 2012. Co-release of hexabromocyclododecane (HBCD) and Nano- and
microparticles from thermal cutting of polystyrene foams. Environmental Science and Technology.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID	1927576
EVALUATION
Domain	Metric	Rating MWF* Score	Comments
* MWF = Metric Weighting Factor
t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
267

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Rosenberg, C.,Hameila, M.,Tornaeus, J.,Sakkinen, K.,Puttonen, K.,Korpi, A.,Kiilunen, M.,Linnainmaa, M.,Hesso, A.. 2011.
Exposure to flame retardants in electronics recycling sites. Annals of Occupational Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1927633
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Number of Sites:
Worker Activity:
Number of Workers:
Type of Sampling:
Exposure Duration:
Disposal
Disposal of Waste of Electric and Electronic Equipment (WEEE)
Dust
Inhalation
8-50 ng HBCD/m3
45
4
The workers were either sorters or dismantlers,or both, or process con-
trollers.
34
personal
191 to 408 min.
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Finland
Metric 3:
Applicability
Unacceptable
x 2
8
Out of scope
Metric 4:
Temporal Representativeness
High
x 2
2
2009
Metric 5:
Sample Size
High
x 1
1
Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness High X 1 1 The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Continued on next page
268

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— continued from previous page
Source Citation:	Rosenberg, C.,Hameila, M.,Tornaeus, J.,Sakkinen, K.,Puttonen, K.,Korpi, A.,Kiilunen, M.,Linnainmaa, M.,Hesso, A.. 2011.
Exposure to flame retardants in electronics recycling sites. Annals of Occupational Hygiene.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927633
EVALUATION
Domain
Metric
Rating MWF* Score Comments

Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 1.8.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
269

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Saito, I.,Onuki, A.,Seto, H.. 2007. Indoor organophosphate and polybrominated flame retardants in Tokyo. Indoor Air.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1927779
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Consumer Use
Insulation products in homes
settled dust
Inhalation
up to 24 ng/m3
18
Concentration in dust
HBCD in dust collected from homes. No associated worker activity.
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
x 1
Methodology is well described
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium
Unacceptable
x 1
x 2
Metric 4: Temporal Representativeness Medium x 2
Metric 5: Sample Size High x 1
2 Japan
8 Non -occupational scenario (settled dust in homes). No associ-
ated worker activites.
4 2006
1 Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.1.

Continued on next page
270

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Saito, I.,Onuki, A.,Seto, H.. 2007. Indoor organophosphate and polybrominated flame retardants in Tokyo. Indoor Air.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927779
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
271

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Saito, I.,Onuki, A.,Seto, H.. 2007. Indoor organophosphate and polybrominated flame retardants in Tokyo. Indoor Air.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 1927779
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Commerical Use
Insulation products in offices
settled dust
Inhalation
up to 29.5 ng/m3
14
Concentration in dust
HBCD in dust collected from offices. No associated worker activities.
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
x 1
Methodology is well described
Domain 2: Representative
Metric 2:
Metric 3:
Geographic Scope
Applicability
Medium x 1
Unacceptable x 2
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Medium
High
x 2
x 1
2 Japan
8 Occupational scenario (use of insulation in offices). No associ-
ated worker activities.
4 2006
1 Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
Medium x 1
2
limited discussion
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 2.1.

Continued on next page
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation:	Saito, I.,Onuki, A.,Seto, H.. 2007. Indoor organophosphate and polybrominated flame retardants in Tokyo. Indoor Air.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID	1927779
EVALUATION
Domain	Metric	Rating	MWF* Score	Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
273

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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Commerical Use
Insulation products in airplanes
dust
Inhalation
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EVALUATION
Domain Metric Rating MWF* Score Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
275
-------
PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EXTRACTION
Parameter Data
Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Number of Samples:
Type of Measurement or Method:
Worker Activity:
Type of Sampling:
Commerical Use
Insulation products in airplanes
dust
Inhalation
0.49 to 490 pmol/m3
9
Concentration in dust
sampled during maintenancework - locations in Table 1
area
EVALUATION

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative

Metric 2:
Geographic Scope
Medium
X 1
2
Sweden
Metric 3:
Applicability
Unacceptable
x 2
8
Out of scope for occupational assessment - this is assessed in

general population exposures
Metric 4:
Temporal Representativeness
High
x 2
2
2014
Metric 5: Sample Size
High
x 1
Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.8.

Continued on next
page

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Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EVALUATION
Domain Metric Rating MWF* Score Comments
** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.
* MWF = Metric Weighting Factor
I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.
277
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Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EXTRACTION
Parameter
Data

Life Cycle Stage:
Life Cycle Description (Subcategory of Use):
Physical Form:
Route of Exposure:
Exposure Concentration (Unit):
Worker Activity:
Consumer Use
Insulation products in homes
settled dust
Inhalation
median = 6 ng HBCD/g dust
HBCD in dust collected from homes. No associated worker activity.
EVALUATION
Domain Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1: Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative
Metric 2: Geographic Scope
Metric 3: Applicability
Metric 4: Temporal Representativeness
Metric 5: Sample Size
Low
Unacceptable
High
High
X 1
x 2
x 2
x 1
3
8
2
1
Egypt
Non-occupational scenario (settled dust in homes). No associ-
ated worker activites.
2015
Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.9.
Continued on next page
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PEER REVIEW DRAFT - DO NOT CITE OR QUOTE
— continued from previous page
Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative

Metric 2:
Geographic Scope
Low
X 1
3
Egypt
Metric 3:
Applicability
Unacceptable
x 2
8
Occupational scenario (use of insulation in offices). No associ-

ated worker activities.
Metric 4:
Temporal Representativeness
High
x 2
2
2015
Metric 5: Sample Size
High
x 1
Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.9.

Continued on next page
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Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative

Metric 2:
Geographic Scope
Low
X 1
3
Egypt
Metric 3:
Applicability
Unacceptable
x 2
8
Non-occupational scenario (settled dust in cars). No associated

worker activites.
Metric 4:
Temporal Representativeness
High
x 2
2
2015
Metric 5: Sample Size
High
x 1
1 Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable
4
Metric Mean Score: 1.9.

Continued on next page
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Source Citation: Strid, A.,Smedje, G.,Athanassiadis, I.,Lindgren, T.,Lundgren, H.,Jakobsson, K.,Bergman, A.. 2014. Brominated flame retar-
dant exposure of aircraft personnel. Chemosphere.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 2343686
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability
Metric 1:
Methodology
High
X 1
1
Methodology is well described
Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:
Geographic Scope
Applicability
Temporal Representativeness
Sample Size
Low
Unacceptable
High
High
X 1
x 2
x 2
x 1
3
8
2
1
China (non-OECD country)
Out of scope
2016
Indicates number of samples and provides several statistics
Domain 3: Accessibility/Clarity
Metric 6: Metadata Completeness
High
x 1
1
Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty
Metric 7: Metadata Completeness
High
x 1
1
The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.
Overall Quality Determination^
Unacceptable

4
Metric Mean Score: 1.9.

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page

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Source Citation: Zeng, Y. H.,Tang, B.,Luo, X. J.,Zheng, X. B.,Peng, P. A.,Mai, B. X.. 2016. Organohalogen pollutants in surface particulates
from workshop floors of four major e-waste recycling sites in China and implications for emission lists. Science of the Total
Environment.
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 3350480
EVALUATION
Domain
Metric
Rating
MWF* Score
Comments

Domain
Metric
Rating
MWF*
Score
Comments
Domain 1: Reliability

Metric 1:
Methodology
High
X
1
1
data or techniques that are high quality
Domain 2: Representative

Metric 2:
Geographic Scope
High
X
1
1
Canada
Metric 3:
Applicability
Unacceptable
X
2
8
Non-occupational scenario (settled dust in homes). No associ-

ated worker activites.
Metric 4:
Temporal Representativeness
High
X
2
2
2011
Metric 5:
Sample Size
Medium
X
1
2
Distribution of samples is characterized by a range with uncer-

tain statistics. It is unclear if analysis is representative.
Domain 3: Accessibility/Clarity

Metric 6:
Metadata Completeness
High
X
1
1
Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.
Domain 4: Variability and Uncertainty

Metric 7:
Metadata Completeness
High
X
1
1
The assessment addresses variability and uncertainty in the

results. Uncertainty is well characterized.
Continued on next page
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Source Citation: Environment Canada and Health Canada. 2011. Screening assessment report on hexabromocyclododecane. Chemical Ab-
stracts Service Registry Number 3194-55-6. Ottawa, Canada.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;
Hero ID 1937209
EVALUATION
Domain
Metric
Rating MWF* Score Comments
Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 1.8.