February 2017 Office of Chemical Safety and Pollution Prevention U.S. EPA Preliminary Information on Manufacturing, Processing, Distribution, Use, and Disposal: N-Methylpyrrolidone (NMP) CASRN: 872-50-4 i Ct t H3 February 2017 Support document for Docket EPA-HQ-OPPT-2016-0743 Page 1 of 22 ------- This document provides a preliminary public summary of available information collected by EPA's Office of Pollution Prevention and Toxics (OPPT) in the Office of Chemical Safety and Pollution Prevention (OCSPP) on the manufacturing (including importing), processing, distribution in commerce, use, and disposal of this chemical. This is based on existing data available to EPA, including information collected under the Chemical Data Reporting rule, Toxic Release Inventory, information from other Agency databases, other U.S. Government agencies, publicly available information from states, and a review of published literature. In addition, the document includes information reported to EPA by producers and users of the chemical in the United States and in other countries. This preliminary use information and any additional use information received in the docket by March 15, 2017 will inform efforts to develop the scope of the chemical risk evaluation required under section 6(b)(4) of the Toxics Substances Control Act, and will inform any risk management efforts following risk evaluation. Mention of trade names in this document does not constitute endorsement by EPA. To verify products or articles containing this chemical currently in commerce, EPA has identified several examples. Any lists are provided for informational purposes only. EPA and its employees do not endorse any of the products or companies. This document does not contain confidential business information (CBI). Page 2 of 22 ------- TABLE OF CONTENTS TABLE OF CONTENTS 3 CONTACT 3 MANUFACTURING, PROCESSING AND USE 4 1. Manufacturing (Including Importing) 4 Manufacturing Process 4 2. Processing 5 3. Products and Articles 7 4. Distribution (Includes Retailers) 14 5. Use 14 Use at Industrial Sites 16 Commercial Uses 16 Consumer Uses 17 6. Disposal of Waste and Recycling/Recovery 17 Recycling and Recovery 17 Disposal of Waste 18 USEFUL TYPES OF INFORMATION 18 APPENDIX: SOURCES CONSULTED 19 LIST OF TABLES Table 1: Overview of NMP Processing (2012 CDR) 6 Table 2. List of Products 7 Table 3: List of Articles 12 CONTACT Ana Corado, Chemical Control Division, Office of Pollution Prevention and Toxics. 202-564-0140, corado.ana@epa.gov Docket: EPA-HQ-OPPT-2016-0743 Page 3 of 22 ------- MANUFACTURING, PROCESSING AND USE 1. Manufacturing (Including Importing) For the 2016 Chemical Data Reporting (CDR) period, data reported indicate that 33 sites in the United States manufacture (including import) NMP1. The total volume (in lbs.) of NMP manufactured (including imported) in the United States in 2012 was 164,311,844; in 2013: 168,187,596; in 2014: 171,095,221; in 2015: 160,818,058. According to information reported to the 2015 Toxics Release Inventory (TRI), 389 facilities reported for NMP2. Of these, 8 facilities reported domestic manufacture, 7 facilities reported import, 153 facilities reported processing, and 289 reported other uses (some sites reported in multiple categories)3. According to TRI, in 2015, 3,043,625 lbs. of NMP were transferred offsite to landfills and/or other treatment/disposal facilities, 5,063,992 lbs. were disposed or released on site for a total of 8,107,617 lbs. of on an off-site disposal or other releases to air, water, and land. Manufacturing Process NMP can be manufactured using different methods. Several references describe two of the methods for manufacturing NMP. 1) Harreus et al describes the typical method of large-scale manufacture of NMP, by reacting butyrolactone with an excess of pure or aqueous methylamine in a high pressure tube 1 Manufacturers (including importers) are required to report under CDR if they meet certain production volume thresholds, generally 25,000 lb or more of a chemical substance at any single site. Reporting is triggered if the annual reporting threshold is met during any of the calendar years since the last principal reporting year. In general, the reporting threshold remains 25,000 lb per site. However, a reduced reporting threshold (2,500 lb) now applies to chemical substances subject to certain TSCA actions, https://www.epa.gov/chemical-data-reporting/how-report-under-chemical-data-reporting 2 A facility must report to the TRI program if it meets all three of the following criteria: 1) is in a specific industry sector, 2) employs 10 or more full-time equivalent employees, and 3) manufactures, processes, or otherwise uses a TRI-listed chemical in quantities above applicable threshold levels for a given chemical in a given year, https://www.epa.gov/toxics- release-inventorv-tri-program/basics-tri-reporting 3 The term "process" in the context of CDR and TRI means the preparation of a chemical substance or mixture, after its manufacture, for distribution in commerce (A) in the same form or physical state as, or in a different form or physical state from, that in which it was received by the person so preparing such substance or mixture, or (B) as part of an article containing the chemical substance or mixture. http://uscode.house.gov/view.xhtml?path=/prelim(5)titlel5/chapter53&edition=prelim The term "otherwise use" under TRI means any use of an EPCRA Section 313 chemical, including an EPCRA Section 313 chemical contained in a mixture or other trade name product or waste, that is not covered by the terms manufacture or process. See the definition of "otherwise use" for additional details on applicability of otherwise use with regard to disposal, stabilization, and treatment for destruction, https://www.epa.gov/sites/production/files/2016- 01/documents/rv 2015 tri reporting forms and instructions.pdf Page 4 of 22 ------- reaction. Harreus states "the reaction is exothermic and often run under adiabatic conditions with reactor temperatures in the range of 250-400 degrees Centigrade. The resulting product mixture is decompressed and distilled. The NMP yield is normally more than 97%." http://onlinelibrarv.wiley.com/doi/10.1002/14356007.a22 457.pub2/abstract;isessionid=52B 5FB0A52B4A4067F738CFF35BCBAAF.f04t02. 2) Johnson-Matthey Process Technologies describes a similar manufacturing process. NMP is produced by reacting gamma-butyrolactone (GBL) and monomethylamine (MMA), which are products of butanediol and methylamines processes respectively. < http://davvprotech.com/what-we-do/licensed-processes-and-core-technologies/licensed- processes/nmp/specification/> The process flowsheet is found at the Johnson-Matthey website. 3) Mitsubishi produces NMP from maleic Anhydride in an integrated manufacturing process at their Mizushima plant. http://www.m- kagaku.co.ip/english/products/business/chemical/c4/details/1194577 3207.html Other methods identified include a non-petroleum-based multi-step process that converts succinic acid into NMP, identified by researchers at the Pacific Northwest National Laboratory (http://iic.pnnl.gOv/abstract/nacs/o 113.pdf), and manufacture of NMP through carbonylation of allylamine (Ullman's Encyclopedia of Industrial Chemistry, Harreus Albrecht L et al). Methods of manufacturing may depend on the specifications for the end use. For example, higher purities of NMP may be required for electronic applications. 2. Processing The processing of NMP includes: Petrochemical processing, including acetylene recovery from cracked gas, extraction of aromatics and butadiene, gas purification (removal of carbon dioxide (CO2) and hydrogen sulfide H2S)), and lube oil extraction Reaction medium for the manufacture of high-temperature polymers such as polyethersulfones, polamideimides and polyaramids Solvent for acrylic and epoxy resins, polyurethane paints, waterborne paints or finishes, printing inks, synthesis/diluent of wire enamels, coalescing agent Solvent and/or co-solvent for liquid formulations of agricultural chemicals Pharmaceutical manufacturing and processing. The table below draws on CDR data to identify the types of processing of the chemical, including processing NMP as a reactant, incorporation into formulation, mixture or reaction products, incorporation into an article, and repacking. Page 5 of 22 ------- Table 1: Overview of NMP Processing (2012 CDR) Industrial Sector (Based on North American Industry Classification System (NAICS)) Industrial Function Type of Processing Adhesives and sealant chemicals Processing-incorporation into formulation, mixture or reaction product Solvent for Adhesives and sealant chemicals Solvents (for cleaning or degreasing) Use-non-incorporative activities Solvents (for cleaning or degreasing) Solvents (for cleaning or degreasing) Processing-incorporation into formulation, mixtures or reaction Solvents (for cleaning or degreasing) Solvents (which become part of product formulation or mixture) Processing-incorporation into formulation, mixture or reaction product Solvents (which become part of product formulation or mixtures) Plating agents and surface treating agents Processing-incorporation into formulation, mixture or reaction Plating agents and surface treating agents Processing aids, not otherwise listed Use-non-incorporative activities Processing aids, not otherwise, listed. Solvents (which become part of product formulation or mixture) Processing-incorporation into article Solvents (which become part of product formulation or mixture) Processing aids, specific to petroleum production Use-non-incorporative activities. Processing aids, specific to petroleum production Paint additives and coating additives not described by other categories Processing-incorporation into formulation, mixture or reaction product Paint additives and coating additives not described by other categories. Painting and Coating Manufacturing Solvents (which become part of product formulation or mixture) Processing-incorporation into formulation, mixture or reaction product Processing aids, not otherwise listed Use-non-incorporative activities Processing aids, not otherwise listed. Intermediates Processing as a reactant Intermediates Printing Ink Manufacturing Paint additives and coating additives not described by other categories Processing-incorporation into formulation, mixture or reaction Paint additives and coating additives not described by other categories Processing-incorporation into article Paint additives and coating additives not described by other categories Page 6 of 22 ------- 3. Products and Articles EPA has identified the following examples. This list is provided for informational purposes only. EPA and its employees do not endorse any of the products or companies. Table 2. List of Products Trade name Use of the product % by weight of chemical Link to references, SDS or industry information Adhesive/Seam Sealer Azek Adhesive Adhesive >85 https://azek.com/docs/technical/AZEK adhesive 2015 SDS sheet.pdf- MSP Seam Sealer Automotive seam < 1 trade http://multimedia.3m.com/mws/mediawebserve sealer secret r?mwsld=SSSSSuUn zu8IOOxl8mxOx2BNv70kl7zH vu9lxtD7SSSSSS- - ALBERDINGK U 801 Binding agent 5-6 http://www.alberdingkusa.eom/fileadmin/pdf/s/ us u 801 s.pdf D9100, D9100SW, D9180 Pressure sensitive adhesive <0.3 http://catalog.berrvplastics.com/catalog- images/410 D9180 11162011.pdf THERMOSET MA-511 Adhesive 1 http://www.lord.com/sites/default/files/THERMO SET%2520MA-511 O.pdf DSB 1520 Adhesive lubricant Not specified http://www.dsbrown.com/Resources/Bridges/Del Adhesive Lubricant astic/B DPPS DSB1520 SDS v012.pdf Cleaner/Remover/Solvent (grout, resin, mold, foam, gasket cleaner/remover/solvent) 3M Sky Restore by Elixair Sealant remover 20-30 http://www.unionesadhesivas.com/wp- Cured Sealant Remover content/uploads/2014/06/MSDS-3M- SkvRestore.pdf LOCTITE SF 75326 CLEAN Solvent 60 -100 http://hvbris.cms.henkel.com/henkel/msdspdf7c UP ountrv=US&language=EN&matnr=234979 Napa Mac's All Parts Cleaner 1 - <3 https://partimages.genpt.com/partimages/71667 Washer Solvent l.pdf RaLex Oven Cleaner Cleaner 1-5 http://prestige2007.com/images/554MSDS%20ov en%20cleaner.pdf BORE CLEANING FOAM, Aerosol foaming 4.5 https://www.krollcorp.com/files/forms/msdsBore BCF-3 bore cleaner CleaningFoamBCF-3-07A.pdf CR-10 Gun Barrel Cleaner Gun barrel cleaner Not specified https://www.barnesbullets.com/files/2014/12/Ba rnes-Bullets-CR102.pdf CHEM-CREST 121 Cleaner (industrial) 90-95 http://www.crest-ultrasonics.com/wp- content/uploads/2013/06/msds-chem-crest- 121.pdf CircuitWorks Conformal Cleaner (electronics) 5-7 http://www.alliedelec.eom/m/d/7d9ecba03559b Coating Remover Pen cf269db7ee80a9c5a28.pdf S-6032A Immersion Solvent 60-80 http://www.cn/stal- Cleaner clean.com/compliance/MSDS/S- 6032A%20Superior%20lmmersion%20Cleaner%2 0Revision%2001-16-14.pdf OIL - BASED STAINLESS Stainless steel 1-5 https://lakeland.edu/PDFs/MSDS/1800/Arrav%20 STEEL CLEANER & POLISH cleaner and polish Stainless%20Steel%20Cleaner%20(US%20Chemic al)%207-7-2012.pdf Aerosol Stainless Steel Aerosol metal Not specified https://resources.cleanitsupplv.com/MSDS/AERO Polish cleaner/ protector SOL%20STAINLESS%20STEEL%20POLISH.PDF Page 7 of 22 ------- Trade name Use of the product % by weight of chemical Link to references, SDS or industry information Epoxy Grout Film Remover Film remover 30-60 https://miraclesealants.eom/msds/c egfr.pdf Pura Insulation Remover Insulation remover 90 -100 http://www.idi-insulation.com/wp- content/uploads/2015/10/Pura Insulation Remo ver MSDS.pdf Mothers Leather Cleaner Car care <1 http://www.homedepot.com/catalog/pdflmages/ fd/fd715fcl-0055-48cb-9fd6-29609b78185b.pdf Slide Bulk Resin Remover Resin remover mold cleaner 30-50 https://www.milacron.com/wp- content/uploads/2016/03/419bulk-Resin- Remover-Mold-Cleaner-SDS.pdf Dynasolve CU-6 Polyurethane remover 40-60 http://www.mccind.com/pdf msds/SDS%20- %20%20Dvnasolve%20CU-6%20.pdf - Green Bean Clean Cleaner 25-50 http://www.davtonsuperior.com/docs/default- source/msds-documents/308468 - green bean clean (usa).pdf?sfvrsn=8- Foam & Resin Cleaner TLS 77 Foam and resin cleaner 41 http://www.tlspecialtv.com/sds/Foam & Resin Cleaner TLS 77%20SDS.pdf- Gasket Remover Gasket remover 10-20 https://www.wisesafetvenv.com/sds/CRC%20IND -Gasket%20Remover-03017-SDS.PDF - Slide Resin Remover Aerosol Aerosol resin remover 35-40 https://www.slideproducts.com/datasheets/pdfs/ Slide-41914-Resin-Remover-OSHA-GHS-SDS.pdf- Gunk HydroSeal II Heavy Duty Parts Cleaner Parts cleaner 2 http://www.rscbrands.eom/products/msds/HS3.p df- Jasco Green Paint Brush Cleaner Paint brush cleaner <5 http://www.iasco- help.com/uploads/documents/QJGBC430 SDS- 808.9.pdf- Goof Off Super Glue Remover Super glue removal 19.7 http://www.goofoffproducts.com/uploads/gener al/GO Super Glue Rmvr FG677 MSDS.pdf- Power Charge Solvent laundry detergent 30-40 http://www.unxinc.com/85349727/1050.pdf- B.G. Air Intake System Cleaner Air intake system cleaner 15-40 http://www.bgfleming.eom/products/msds/206.p df- WallGlide TileFoam Plus Tile cleaner 1-5 https://servicemasterportal.s3.amazonaws.eom/s afetv data/28074.pdf - Sprayway Home maintenance cleaner 15-25 https://householdproducts.nlm.nih.gov/cgi- bin/household/brands?tbl=brands&id=19038052 Reclaimed NMP Solvents and other uses 99.5 http://www.veolianorthamerica.com/en/our- services/waste-services/n-methylpyrrolidone- sale?gclid=CJ7kmL PutECFYs6gQodi4QMEQ Coating/Resin/Paint/Rust Inhibitor/Wood Finisher/Sealant BYK-410 Rheology additive, coating thickener 48-49 http://www.palmerholland.com/Assets/User/Doc uments/Product/41535/1353/M ITM02282.pdf- United Coatings Kymax Coating PVDF fluoropolymer resin 1-5 http://www.gaf.com/Commercial Roofing Svste ms/Liauid Applied Roofing/Roof Coatings/UNIT ED COATINGS Kvmax Coating/United Coatings Kvmax Coating.pdf- Buckeye Arena 200 Wood floor coating 1-5 http://www.buckeveinternational.com/media/Ar ena2005171.pdf- MT Concrete Seal Concrete floor coating 1 - < 3 https://www.hillyard.com/lmages/MSDS/MSDSHI L00492.pdf - Isolflex 760 Lockcoat Aromatic Part A Coating 3 http://www.lvmtal.com/msds/if760ar msds.pdf - Two MSDSs - only 1 with NMP Page 8 of 22 ------- Trade name Use of the product % by weight of chemical Link to references, SDS or industry information Vara HD Spar Varnish Semi-Gloss VA Top coat/varnish 1-2.5 http://www. homedeDot.com/catalog/Ddf Images/ c5/c59d2d20-deaa-476a-894e-c7befda3a539.Ddf Staticide Premium ESD Paint Paint for concrete 4-7 htto://www.aclstaticide.com/safetv datasheets/ 5700SDS 16.pdf- Hydrophilic Coating Formula B Hydrophilic coating <2.5 http://coatings2go.com/wp/wp- content/uploads/2015/03/Formula B- all versionsl n.pdf- Marine Instant Galvanize Coating <0.3 http://www.crcindustries.com/faxdocs/msds/605 4.pdf- Formgard TJ 450 Rust inhibitor for steel CBI http://www.nox-crete.com/wp- content/uploads/2014/03/FORMGARD-TJ-450- SDS.pdf- Zar Exterior Water Based Polyurethane - All Gloss Levels Wood finish varnish 3-7 http://www.zar.com/wp-content/uploads/Zar- Exterior-Water-Based-Polvurethane-AII-Gloss- Levels-SDS.pdf- Minwax Polyacrylic Water-Based Protective Finish Clear Gloss Clear gloss protective finish 1.71 http://www.minwax.com/document/SDS/en/US/ 027426155558 - BonaSport Super Sport Wood gym floor finish <5 https://www.bona.com/Global/Countries/United %20States/MSDS/Bona%20Supersport%20Finish %20MSDS.pdf- Skybondฎ 705 Polyimide Resin Polyimide Resin 60-63 http://www.istusa.com/pdf/msds/SB/IST Skvbon d 705 SDS.pdf- Bright Zinc-Itฎ Instant Cold Galvanize Coating <0.3 https://www.revnoldsonline.com/ASSETS/DOCU MENTS/ITEMS/EN/CRCC18414 MSDS.pdf- MIL-DTL-64159B Type ll/lll Component B, Catalyst Touch-up military paint 1-5 http://www.milsprav.com/assets/files/sds/MIL- DTL-64159B%20Tvpe%20ll-lll%20- %20Component%20B%20Catalvst%20(SCI).pdf HD 8820 Polyimide coating for semi-conductor industry <1 https://wcam.engr.wisc.edu/Public/Safetv/SDS%2 0-%20GHS/SDS%20E-COPY/Polvimide%20HD- 8820.pdf KBS RustSeal Rust preventive 0-1 https://www.winzerusa.com/ecat/msds/891 180 2 7.pdf Gloss Topcoat Concentrate/TC-1 Top-coating 9-10 http://advleather.com/MSDS-TC-l.pdf BOB WB URETHANE/ACRYUC SEALER Sealer 1-5 http://www.spec- west.com/uploads/3/Spec West/MSDS/BOB MS DS.pdf LIQUID 2 POWDER Powder coating surface preparation <1 http://www.powderbuvthepound.com/pdf/MSDS %20L20.pdf STOPGAP F76 RESIN Component of epoxy resin based system <1 http://www.f-ball.com/wp- content/uploads/safetv.f76-resin.en.pdf DUPLI-COLORฎ Clear Truck Bed Coating (Aerosol) Aerosol 0.28 http://s7d9.scene7.com/is/content/GenuineParts Companv/3133889pdf?$PDF$ Polyurethane Curative WC-788 Part B-180 Polyurethane curative .129 https://bibenterprises.com/media/wysiwyg/pdfs/ Water-Clear-Shore-D/WC-788 Part B-180.pdf PETTIT VIVID GREEN 1361 Paint Not specified http://doc.iamestowndistributors.com/userportal /pdfs/MSDS/Pettit/Pettit Vivid 1361 Green SDS .pdf Page 9 of 22 ------- Trade name Use of the product % by weight of chemical Link to references, SDS or industry information Stripe Orange Fluorescent (Solvent) Solvent for paintings and coatings .36 http://www.sevmourpaint.com/wp- content/uploads/2014/ll/20-957-SDS.pdf Cosmetics/Personal Care Products All or 1 Artificial Nail Remover - Various (Lemon, Orange, Lemon Extracts, Orange Oil) Nail polish remover/solvent N/A safecosmetics.cdph.ca.gov Under CAS 872-50-4 Blonde Bombshell Hair styling product N/A safecosmetics.cdph.ca.gov Under CAS 872-50-4 Clear Action Day Treatment Skin moisturizer N/A safecosmetics.cdph.ca.gov Under CAS 872-50-4 Korres Abyssinia Oil Mascara Various Mascara N/A safecosmetics.cdph.ca.gov Under CAS 872-50-4 TexasLash Mascara Mascara N/A http://www.cargocosmetics.com/texaslash- mascara.html> Proactivator Nail Bonder Nail adhesive N/A safecosmetics.cdph.ca.gov Under CAS 872-50-4 5 Second Stop Fungus Nail Treatment Fungus nail treatment N/A http://www.5secondnail.com/ https://www.amazon.com/Second-Nail-Stop- Fungus- Treatment/dp/B001KYQG3U#customerReviews. http://www.ewg.Org/skindeep/product/465807/5 Second Stop Fungus Nail Treatment/ DARIYA Salon De Pro Hair Manicure Speedy Dye, No. 4 Light Brown, 0.5 Pound Hair dye N/A https://www.amazon.com/DARIYA-Salon- Manicure-Speedv- Light/dp/B000V2F3AE/ref=sr 1 18 a it?ie=UTF8 &aid=1485278275&sr=8- 18&kevwords=methvl+Pvrrolidone LOMBOK Mastic LPP treatment 1000ml Hair treatment N/A https://www.amazon.com/LOMBOK-Mastic- treatment-1000ml- Korea/dp/BOOJFITJRS/ref=sr 1 36 a it?ie=UTF8& aid=1485278476&sr=8- 36&keywords=methyl+pyrrolidone Dyes and Inks Silver Conductive Ink - Standard Silver conductive ink for 3D printable electronics <15 http://p4.zdassets.com/hc/theme assets/638849 /200059206/Voxel8 conductivesilverink SDS.pdf Note: Listed as "Cyclic amide" CN816Series Inkjet printing <5 http://h22235.www2.hp.com/hpinfo/globalcitize nship/environment/productdata/Countries/us/lf cn816series us eng v08.pdf FR-1 RED CONCENTRATE Dye 97-98 http://www.advanced- plastics. com/msds/D61 150223%20SDS.pdf LEATHER FINISH BLACK W-3000 Leather dye 2-5 http://www. suedeproducts. com/MS DS/BLACK%2 0W-3000.pdf HPS-108AE1 High Performance Silver Ink Commercial ink (Nano) 0-5 http://store.novacentrix.eom/v/vspfiles/assets/i mages/HPS- 108AEl%20High%20Performance%20Silver%20ln k.pdf- Page 10 of 22 ------- Trade name Use of the product % by weight of chemical Link to references, SDS or industry information JP-K81 Printing Ink Printing ink 1-5 http://www.hitachi- america.us/supportingdocs/forbus/inkietprinters/ msds/english/ink tvpes/hitachi-material-safetv- data-sheet-ip-k81-printing-ink.pdf Thinner 2732 Ink thinner 30-60 http://baltimoreprintstudios.com/wp- content/uploads/2012/06/msds retarder thinne r nazdar.pdf Grout Quartz-Lock Grout, Tile grout 1.47 http://www.greenbuildingsupplv.com/core/medi Product #120120 a/media. nl?id=43507&c=772072&h=25f7a394e62 8431cc9bc Miscellaneous Nycast Type 6 Cast Nylon Cast nylon (industrial <5 http://www.alro.com/datapdf/plastics/plasticsms and Type 12 Cast Nylon use) ds/sds castnvlon.pdf ALL-WEATHER Plastic Ear Weather-resistant 10-20 http://www.markal.eom/assets/l/7/aw plastic e Tag Marker marker for polyurethane tags artag white medtip.pdf Leather Repair Filler 4 https://leathermagic.com/wp- Compound content/uploads/LthrRepCompoundMSDS.pdf AQUACREME Glazing material 2.1 http://fauxfx.com/SDS/aauacremeghssds.pdf Buckeye Equity Buffing floor finish <1 http://www.buckeyeinternational.com/media/Eq enhancer uity5108.pdf BYK-410 Foam stabilizers 30-60 http://www.sfm.state.or.us/CR2K SubDB/MSDS/ BYK 410.PDF Pesticides MATADOR Herbicide Not specified https://s3-us-west- 1. amazonaws.com/www.agrian.com/pdfs/Matad or MSDS2.pdf LONGRANGE Parasiticide 30 https://www.henrvscheinvet.eom/Content/SDS/0 45372.pdf Bayluscide 20% Niclosamide 64-68 http://www.glfc. org/sealamp/sop2015/app/app% Emulsifiable Concentrate; ethanolamine salt 20f%20S DS%20Bayluscide%2020%20percent%20 Bayluscide Emulsifiable mixture; clonitralide Emulsifiable%20Concentrate.pdf Concentrate Lampricide mixture Tekko Pro Insect growth regulator 20 http://www.domvownpestcontrol.com/msds/Tek ko Pro MSDS.pdf SUBDUE GR Granular fungicide <5 http://www.kellvsolutions.com/erenewals/docu mentsubmit/KellvData%5CAK%5CPesticide%5CM SDS%5C100ฐ/o5C100- 794%5CSUBDUE GR 4 15 2016 1 57 13 PM.p df Enforcer Formula 111 E.C. Weed killer 1-5 https://sds.zepinc.com/ehswww/zep/result/direc Weed Killer t link.isp?P LANGU=E&P SYS=2&P SSN=11337& C001=MSDS&C002=US&C003=E&C013=1048552 &C123=SDS* Prentox CFT Legumine Piscicide 10 http://www.zoecon.com/-/media/files/zoecon- Fish Toxicant na/us/product%20labels/sds/cft%20legumine%20 fish%20toxicant%20sds.pdf Sergeants PetArmor Plus Dog flea and tick 20-40 https://householdproducts.nlm.nih.gov/cgi- bin/household/brands?tbl=brands&id=19049008 Page 11 of 22 ------- Trade name Use of the product % by weight of chemical Link to references, SDS or industry information Paint Stripper/Graffiti Remover Safety Strip 5896B Industrial strength stripper <80 http://www. brulin.com/cmsassets/file/msds/331 022 msd.pdf Peel Away 5 Soy Based Soy based paint stripper 25-30 https://www.dumondchemicals.eom/pdf/MSDS/P eel Awav 5 Sov Based.pdf HCS 401 Ink Remover Ink remover 1-60 http://www.progressive-recoverv.com/wp- content/uploads/2016/03/HCS-401-INK- REMOVER-12-15-2015-No-PRI-.pdf- Photo Resist (usually Printed Circuit Board Manufacturing) Remover PG Photoresist Not specified https://louisville.edu/micronano/files/documents /safetv-data-sheets-sds/copv of RemoverPG.pdf Remover PG Photoresist Remover Photoresist Remover >99 httpV/www.binghamton.edu/nano/documents/g hs removerpg revO.pdf- Sealant/Leak Sealant Enviroseal Acrylic Sealer Floor Sealant Acrylic 0.1 -< 1.0 http://www.state, in. us/idoc/penproducts/files/S DS US English - FL-2126- D ENVIROSEAL ACRYLIC SEALERwHMIS.pdf Rohper LSPR Leak Seal Clear Aerosol leak sealer .1-1 http://www.rustoleum.com/MSDS/ENGLISH/267 453.pdf Turtle Wax 2 in 1 Headlight Cleaner & Sealant Automotive headlight sealant and cleaner 0.2 https://www.turtlewax.com/docs/default- source/msds-english/msds-consumer/t43 - Soldering Flux TSF 6522 TACKY SOLDERING FLUX TSF 6522 TACKY SOLDERING FLUX Soldering flux 1-2.5 http://www.kester.com/DesktopModules/Bring2 mind/DMX/Download.aspx?Command=Core Do wnload&Entrvld=1169&language=en- US&Portalld=0&Tabld=96 Wood Preservative MP400-EXT Wood preservative for utility poles <1 http://www.kellysolutions.com/erenewals/docu mentsubmit/KellyData%5COK%5Cpesticide%5CM SDS%5C75341%5C75341-14%5C75341- 14 MP400 EXT 3 3 2016 9 54 21 AM.pdf Table 3: List of Articles Trade name Use of the article % by weight of chemical Link to references, SDS or industry information Lithium Ion Battery Lithium ion battery 0-1 http://www.officedepot.eom/pdf/msds/469830.p df Nycast Type 6 Cast Nylon and Type 12 Cast Nylon Cast nylon industrial use <5 http://www.alro.com/datapdf/plastics/plasticsms ds/sds castnvlon.pdf Arts/Crafts/Variety Packs (numerous) Chilidren's arts and crafts products (Gels, Creams, Powders, Liquids, Adhesives, synthetic fragrances) 5000- 10000 ppm NMP Reported to State of Washington under the Children's Safe Product Act https://fortress.wa.gov/ecv/cspareporting/Report s/ReportViewer.aspx?ReportName=ChemicalRepo rtByCASNumber easy-graft CLASSIC (biolinker portion) Dental bone graft substitute 85 http://us.guidor.com/media/guidor Pdfs/SDS ea sv-graftCLASSIC V02.pdf Page 12 of 22 ------- Trade name Use of the article % by weight of chemical Link to references, SDS or industry information Children's Sportswear, Clothing and Underwear various Children's sportswear, clothing and underwear various <500 PPm Reported to State of Washington under the Children's Safe Product Act httos://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Dolls/Soft Toys Various Dolls/soft toys various 500- 1000 PPm Reported to State of Washington under the Children's Safe Product Act https://fortress.wa.gov/ecy/cspareporting/Report s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Children's Footwear Children's footwear <100 PPm Reported to State of Washington under the Children's Safe Product Act httDs://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Children's Belts/Braces/Cumberbund s Various Children's belts/braces/ cumberbunds various 100- 500 PPm Reported to State of Washington under the Children's Safe Product Act httDs://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Baby Feeding/Bibs Various Baby feeding/bibs Various <100 PPm Reported to State of Washington under the Children's Safe Product Act httDs://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Children's Clothing/ Dresses/Trousers/ Shorts/Bodysuits Various Children's clothing/ dresses/ trousers/ shorts/bodysuits Various <100 ppm Reported to State of Washington under the Children's Safe Product Act httDs://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Children's Bedding Various Blankets/throws < 100 ppm Reported to State of Washington under the Children's Safe Product Act httDs://fortress. wa.gov/ecv/csDareDorting/ReDort s/ReDortViewer.asDX?ReDortName=ChemicalReDO rtBvCASNumber Note: In January 2017, EPA proposed restrictions on the use of NMP in commercial and consumer paint and coating removal (82 FR 7464). Page 13 of 22 ------- 4. Distribution (Includes Retailers) Based on information reported to TRI for 2015, ten facilities manufacture NMP for sale or distribution. Based on information reported to CDR for 2016, seven facilities manufacture NMP for wholesale and retail trade. Because of the wide variety of NMP uses and NMP-containing products and articles, distribution of NMP also varies depending on the use, product or article. NMP can be purchased directly through online retailers, through chemical distributors and through a variety of retailers and businesses depending on the NMP-containing product or article. Industrial and commercial users may purchase through chemical distributors - online or directly from suppliers such as industrial supply stores. Distribution of products and articles to commercial businesses and consumers may be through online purchasing or again directly from retailers. For example, adhesive remover such as Goof Off SuperGlue Remover can be purchased online, at HomeDepot and through many other supply stores (http://www.homedepot.com/p/Goof-Off-4-oz- Super-Glue-Remover-FG677/204055736). Adhesives with NMP, whether for commercial, construction or consumer use, may be purchased online, at hardware or arts/crafts stores or through commercial distributors. For example, Azek Adhesive is found in the store at Lowe's and Home Depot as well as online. EPA also identified an NMP product, (greater than 95% NMP), produced from recycling NMP, for sale online. Source: http://www.veolianorthamerica.com/en/our-services/waste-services/n-methvlpyrrolidone- sale?gclid=CJ7kmL PutECFYs6gQodj4QMEQ. 5. Use NMP is an effective solvent used in a wide variety of industrial, commercial and consumer uses (Harreus et al., 2011). NMP has an extensive array of industrial, commercial and consumer uses, past and potential, including: Solvent for resins, waxes, paints/coatings, arts/crafts, adhesives, acetylene, industrial cleaning, consumer cleaning products, mold cleaning (including agricultural molds), polyurethane processing; Chemical extraction of acetylene, BTX and butadiene, synthetic resin surface coating solvent, reaction solvents (PPS, polyimide, etc); Adhesives, bioadhesives and sealants in a wide variety of commercial, consumer and children's products; Pipe cement; Cleaning agent for equipment, surfaces, tanks, floors, walls, laundry and laundry spot remover; Metal finishing; Wood preservative ingredient; Page 14 of 22 ------- Printed circuit board manufacturing, semiconductor parts cleaning, semiconductor photo-resist thinner, color filter photo-resist thinner; Wax/flux/polymeric residue removal; Lithium battery manufacturing; Dehydration of natural gas; Spinning agent for PV; Lube oil processing; Petrochemical processing; Spinning agent for PVC; Chemical intermediate; Pigment dispersant and dyes (such as shoe colorant); Automotive mold cleaning and automotive metal parts cleaning; Printing, printing inks (lithographic and screen) and print cleaning; Optical plastic lens manufacturing equipment cleaning; Cosmetic products; Skin penetration enhancer; Textiles and clothing; Adjuvant for slimicides in food contact paper; Solvent in food contact polysulfone and PES resins; Pharmaceutical and agricultural chemical manufacturing solvent, cleaning, extraction; Veterinary pharmaceuticals; Laboratory uses; Synthesis of Vitamin E precursors; Hydraulic Fracking. Source: Ash, Michael and Irene. Specialty Chemicals Source Book. 4th edition vol 2. 2009, EU Annex XV Restriction Report NMP https://echa.europa.eu/documents/10162/13641/nmp annex xv report en.pdf Mitsubishi Chemicals cites the following industrial and commercial uses for NMP: Electronics: Wax/flux removal, Burr removal, Electronics Parts Cleaning, Semiconductor Parts Cleaning, Solvent for Lithium Battery Manufacturing, Semiconductor Photo-Resist Thinner, Color Filter Photo-Resist Thinner Automotive: Mold Cleaning, Metal Parts Cleaning Chemical: Extract agent (acetylene, BTX, butadiene), Synthetic resin surface coating solvent, Reaction solvents (PPS, polyimide, etc.), Equipment washing. Optical: Plastic Lens manufacturing equipment cleaning Pharmaceutical and Agricultural Chemicals: Water-soluble solvent, Cleaning, Extraction. Source: http://www.m- kagaku.co.ip/english/products/business/chemical/c4/details/1194577 3207.html Page 15 of 22 ------- NMP has also been reported to be used in hydraulic fracking. The April 2011 Report of the U.S. House of Representatives Committee on Energy and Commerce Minority Staff on Chemicals Used in Hydraulic Fracking identified at least one NMP-containing product used in hydraulic fracking. Source: http://www.conservation.ca.gov/dog/general information/Documents/Hyd raulic%20Fracturing%20Re port%204%2018%2011.pdf. Use at Industrial Sites As mentioned above, NMP is widely used as a solvent in chemical and chemical processing, electronics, as well as in wide variety of industries, including manufacturing of solvents, pesticides, paints, coatings, auto, pharmaceuticals, adhesives and other product formulations. Uses of NMP in fracking have been identified but not well characterized. The functional uses of NMP at industrial sites include: Solvent uses (which become part of product formulation or mixture) Coatings as ingredient in both solvent and water based coatings including wire coatings Processing agent and incorporation into a formulation, mixture or reaction product Processing agent and incorporation into an article Processing as a reactant Paint additives and coating additives not described by other categories Electronics: cleaning agent for silicon wafers, photoresist stripper, auxiliary in printed circuit board technology Paint and coating removal (brush, spray, and immersion) Heated solvent and/or paint remover Non-incorporative activities Industrial and domestic cleaning: component in paint strippers and degreasers (e.g. removal of oil, fat and soot from metal surfaces and carbon deposits and other tarry polymeric residues in combustion engines) Commercial Uses Commercial uses are wide and varied. They include: Automotive/autobody sectors (autobody painting, wheel stripping, antique auto restoration, ground vehicle maintenance) Cleaning (floor stripping, equipment cleaning, tank cleaning among others) Furniture refinishing Specialized cleaning in optics Electronic/computer manufacturing uses (printed circuit board manufacturing, defluxing/semiconductors) Lithographic/silk screen printing Art restoration and conservation Nail salon uses (in remover) Page 16 of 22 ------- Construction and building uses (coatings, paints, adhesives, binders, sealants and removers including edge bead remover, waterproofing) use of NMP-containing products by professional contractors of all kinds Graffiti removal by municipalities, transit agencies and commercial real estate managers Laboratory uses including as a reagent. Consumer Uses While many products that contain NMP seem to be intended for industrial and commercial uses, NMP is found in a variety of products used by consumers including: Paints Paint strippers Furniture strippers Cleaners (for oven cleaning, floor/surface cleaning and floor stripping) Adhesives (general) Leather treatments Adhesives for arts/crafts, children's arts/crafts, hobby products Surfactants and other uses in Personal Care Products (mascara, hair dye, hair treatment, nail treatment) Clothing/Footwear (children's clothing, footwear, accessories) Textiles/Bedding The Washington Department of Ecology Safer Children's Products Database lists 53 children's products reported by manufacturers to contain NMP. Some pet care products including flea treatments may contain NMP. NLM's Household Products database lists a dog flea treatment containing 20-40% NMP. 6. Disposal of Waste and Recycling/Recovery Recycling and Recovery Veolia North America advertises on Amazon selling "N-Methyl-2-pyrrolidone For Sale" stating the company "recovers solvent from industrial processes across the United States at its four locations in Azusa, CA, Henderson, CO, West Carrollton, OH and Middlesex, NJ." Veolia states that its "reclaimed solvents are typically 99.5% minimum purity and much more competitively priced than virgin solvents." Source: http://www.veolianorthamerica.com/en/our-services/waste-services/n-methvlpyrrolidone- sale Page 17 of 22 ------- Disposal of Waste According to TRI, in 2015, 8,107,617 lbs. of NMP were disposed or released, including 5,063,992 lbs. of NMP released or disposed onsite and 3,043,625 lbs. of NMP released or disposed offsite. Of the onsite releases of 5,063,992 lbs, 3,623,299 lbs. were primarily released to onsite Underground Injection Control (UIC) Class 1 wells and another 1,440,593 lbs. to onsite releases to air from point sources or fugitive sources and surface water. Of the offsite TRI releases or disposal of 3,043,625 lbs. reported in 2015, 2,789,548 lbs. were released to offsite landfills, RCRA Subtitle C landfills or UIC Class 1 wells located offsite, and 254,077 lbs. were released offsite through other land disposal, waste brokers, storage and land treatment. In terms of handling and disposal, NMP is classified as a combustible liquid and should be stored in approved safety containers, properly labeled as to their contents and hazard. Source: http://infohouse.p2ric.org/ref/30/29008.pdf. Safety Data Sheets for NMP frequently indicate, "While this material is not specifically defined or listed by RCRA rules, it is recommended that disposition of material be done in accordance with Federal, Regional, State, Provincial and/or local rules and regulations." Source: http://amdg.ece.gatech.edu/msds/solvents/N-methvl-2-pyrrolidone.pdf The International Chemical Safety Card under the "Spillage Disposal" Section offers the following guidance: "Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Personal protection: filter respirator for organic gases and vapours." Source: https://www.cdc.gov/niosh/ipcsneng/neng0513.html. USEFUL TYPES OF INFORMATION This document presents a summary of information currently available to EPA on this chemical. To more fully characterize the manufacturing, processing, distribution, disposal, and use of this chemical, and to inform the development of the scoping document for this chemical, EPA is interested in obtaining information on: the functional uses for this chemical; what types of products contain this chemical; which industry sectors use this chemical; what volume of the chemical is used; which uses have been discontinued or phased out; exposure scenarios for this chemical; and in which articles this chemical is found. Page 18 of 22 ------- APPENDIX: SOURCES CONSULTED U.S. EPA Chemical Inventory https://www.epa.gov/tsca-inventory U.S. EPA ChemView https://iava.epa.gov/chemview TRI P2 information https://www.epa.gov/toxics-release-inventory-tri-program/pollution-prevention-p2-and-tri U.S. EPA HPV HC (access through Chemical Data Access Tool - CDAT) https://java.epa.gov/oppt chemical search/ U.S. EPA HPVIS and HPV HC (access through Chemical Data Access Tool - CDAT) https://java.epa.gov/oppt chemical search/ DfE Alternatives Assessments https://www.epa.gov/saferchoice/design-environment-alternatives-assessments Safer Chemical Ingredients List https://www.epa.gov/saferchoice/safer-ingredients Green Chemistry awards https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-winners Greener products and services https://www.epa.gov/greenerproducts/identify-greener-products-and-services Pollution Prevention https://www.epa.gov/p2/pollution-prevention-case-studies https://www.epa.gOv/p2/grant-programs-pollution-prevention#sra https://www.epa.gov/p2/pollution-prevention-tools-and-calculators U.S. EPA InertFinder https://iaspub.epa .gov/apex/pesticides/f?p=101:l: U.S. EPA Pesticide Chemical Search https://iaspub.epa .gov/apex/pesticides/f?p=CH EM ICALSEARCH:1:0::NQ:1:: U.S. EPA Endocrine Disruptor Screening Progmrn https://www.epa.gov/ingredients-used-pesticide-products/endocrine-disruptor-screening- program-tier-l-assessments U.S. EPA Hgzgrdous Wgste https://www.epa.gOv/hw/learn-basics-hazardous-waste#regulations U.S. EPA Superfund chemicgl dgtg mgtrix https://www.epa.gov/superfund/superfund-chemical-data-matrix-scdm-query U.S. EPA Hgzgrdous Air Pollutgnts https://www.epa.gov/haps/initial-list-hazardous-air-pollutants-modifications U.S. EPA Significgnt New Alterngtives Policy (SNAP) https://www.epa.gov/snap U.S. EPA Volgtile Orggnic Compounds https://www.epa.gov/indoor-air-qualitv-iaq/technical-overview-volatile-organic- compounds#definition U.S. EPA Toxic gnd priority pollutgnts under the Clegn Wgter Act https://www.epa.gOv/eg/toxic-and-priority-pollutants-under-clean-water-act#toxic Page 19 of 22 ------- U.S. EPA Contaminant Candidate list under the Safe Drinking Water Act https://www.epa.gOv/ccl/contaminant-candidate-list-3-ccl-3#chemical-list U.S. EPA IRIS Assessment https://cfpub.epa.gov/ncea/iris2/atoz.cfm U.S. EPASffS https://iaspub.epa.gov/sor internet/registry/substreg/searchandretrieve/substancesearch/search. do U.S. EPA Chemical and Product Categories (CPCat) Database https://actor.epa.gov/cpcat/faces/home.xhtml U.S. National Library of Medicine ChemlDplus https://chem.sis.nlm.nih.gov/chemidplus/ U.S. National Library of Medicine Hazardous Substance Data Bank (HSBD) https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm U.S. Department of Health & Human Services Household Products Database https://hpd.nlm.nih.gov/index.htm OSHA Chemical Hazards and Toxic Substances https://www.osha.gov/SLTC/hazardoustoxicsubstances/index.html NIOSH Workplace Safety and Health Topics Chemicals http://www.cdc.gov/niosh/topics/chemical.html NIOSH Pocket Guide to Chemical Hazards http://www.cdc.gov/niosh/npg/npgdcas.html CPSC Chemicals http://www.cpsc.gov/en/Research--Statistics/Chemicals/ CPSC FHSA https://www.cpsc.gov/Business--Manufacturing/Business-Education/Business-Guidance/FHSA- Requirements/ Food and Drug Administration List of Databases http://www.fda.gov/Forlndustrv/FDABasicsforlndustry/ucm234631.htm NTP (National Toxicology Program) Substances studied by NTP http://ntpsearch.niehs.nih.gov/?e=True&ContentType=Testing+Status Department of Energy Protective Action Criteria Database http://energy.gov/ehss/protective-action-criteria-pac-aegls-erpgs-teels-rev-29-chemicals-concern- may-2016 California Department of Toxic Substances Control Toxics in Products http://www.dtsc.ca.gov/PollutionPrevention/ToxicslnProducts/index.cfm http://www.dtsc.ca.gov/SCP/CandidateChemicalsList.cfm http://www.dtsc.ca.gov/SCP/WhatlsAPriorityProduct.cfm California Office of Environmental Health Hazard Assessment Proposition 65 http://oehha.ca.aoWproposition-65/chemicals http://oehha.ca.gov/proposition-65/proposition-65-list California Office of Environmental Health Hazard Assessment Biomonitoring http://biomonitoring.ca.gov/chemicals California permissible exposure limits for chemical contaminants https://www.dir.ca.gov/title8/5155table acl.html Page 20 of 22 ------- California hazardous substance list https://www.dir.ca.gov/title8/339.html California Safe Cosmetics Program - list of chemical agents known or suspected to cause cancer or developmental or other reproductive harm. http://www.cdph.ca.gov/programs/cosmetics/Pages/default.aspx https://safecosmetics.cdph.ca.gov/search/Default.aspx Maine chemicals of high concern http://www.maine.gov/dep/safechem/highconcern/ Massachusetts Toxics Use Reduction Act (TURA) (link includes a link to Higher hazard substances list) http://www.mass.aov/eea/waste-mant-recyclina/toxics/toxic-use-reduction/toxics-use-reduction- gctl Massachusetts Complete list of TURA chemicals http://www.mass.gov/eea/agencies/massdep/toxics/tur/toxics-use-reduction-act-tura-reporting- and-fees.html Lowell Center for Sustainable Production Chemical, Policy and Science Initiative http://www.chemicalspolicv.org/chemicalspolicy.us.state.database.php Minnesota Department of Health Toxic Free Kids Act Chemicals of High Concern http://www.health.state.mn.us/divs/eh/hazardous/topics/toxfreekids/highconcern.html Michigan Environmental Health Topics http://www.michigan.gOv/mdhhs/0.5885.7-339-71548 54783 54784 74881-13050--.00.html New Hampshire Regulated Toxic Air Pollutants http://des.nh.gov/organization/commissioner/legal/rules/documents/env-al400.pdf New Jersey Right to Know Hazardous Substances http://web.doh.state.nj.us/rtkhsfs/rtkhsl.aspx Oregon Priority Persistent Pollutants (in water) http://www.deq.state.or.us/wq/SB737/ Oregon Pollutant Profiles http://www.deq.state.or.us/wq/SB737/docs/LegRpAtt420100601.pdf Oregon Reducing Toxics in Oregon http://www.oregon.gov/deq/Pages/ToxicsReduction.aspx Oregon Chemicals of Concern for Children's Health http://public.health.oregon.gov/HealthvEnvironments/HealthyNeighborhoods/ToxicSubstances/Pa ges/childrens-chemicals-of-concern.aspx Pennsylvania Department of Labor and Industry Hazardous Substance List http://www.pacode.com/secure/data/034/chapter323/chap323toc.html Rhode Island Air Resources - Air Toxics http://www.dem.ri.gov/pubs/regs/regs/air/air22 08.pdf Vermont Chemical Disclosure Program for Children's Products http://www.healthvermont.gov/enviro/chemical/cdp.aspx Washington Chemicals of High Concern to Children http://www.ecv.wa.gov/programs/hwtr/rtt/cspa/chcc.html Washington Children's Safe Products Act http://apps.leg.wa.gov/RCW/default.aspx?cite=70.240 Page 21 of 22 ------- Washington Department of Labor & Industries SHARP Publications http://www.lni.wa.gov/Safety/Research/Pubs/default.asp National Conference of State Legislatures http://www.ncsl.org/research/environment-and-natural-resources/state-chemical-statutes.aspx Canada Chemicals Portal http://chemicalsubstanceschimiques.gc.ca/index-eng.php EU ECHA website https://echa.europa.eu/ Australia NICNAS Chemical Information https://www.nicnas.gov.au/chemical-information Japan Chemical Risk Information Platform (CHIRP) http://www.nite.go.jp/en/chem/chrip/chrip search/systemTop OECD eChemPortal http://www.echemportal.org/echemportal/index?pagelD=Q&request locale=en Stockholm Convention on Persistent Organic Pollutants http://chm.pops.int/TheConvention/ThePOPs/ListingofPOPs/tabid/25Q9/Default.aspx http://chm.pops.int/TheConvention/ThePOPs/ChemicalsProposedforListing/tabid/251Q/Default.as fix WHO IPCS (UN) http://www.who.int/ipcs/en/ Other-worker protection information http://www.dguv.de/ifa/gestis/gestis-internationale-grenzwerte-fuer-chemische-substanzen-limit- values-for-chemical-agents/index-2.jsp DeLima Associates Consumer Product Information Database (CPID) https://www.whatsinproducts.eom/chemicals/index/l SRC FatePointers Search Module PHYSPROP http://esc.syrres.com/fatepointer/search.asp Product and company websites Page 22 of 22 ------- |