Fact Sheet: Fifth Contaminant

Environmental Protection

*"""	Candidate List (CCL 5)	

EPA has published the Contaminant Candidate List 5 (CCL 5). The final CCL 5 includes 66
chemicals, 3 chemical groups and 12 microbial contaminants which are known or anticipated to
occur in public water systems. The CCL 5 includes contaminants used in commerce, pesticides,
waterborne pathogens, disinfection byproducts, and biological toxins. In developing the CCL 5,
EPA implemented improvements to the CCL process to better identify, screen, and classify
potential drinking water contaminants. These improvements resulted in a CCL 5 that can better
support prioritization of contaminants for regulatory decisions and research efforts.

Questions and Answers

What is the drinking water Contaminant Candidate List?

The drinking water Contaminant Candidate List (CCL) is a list of contaminants that are currently
not subject to any proposed or promulgated national primary drinking water regulations but are
known or anticipated to occur in public water systems. Contaminants listed on the CCL may
require future regulation under the Safe Drinking Water Act (SDWA). EPA uses the CCL to
identify priority contaminants for regulatory decision making and information collection needs.

How often is the CCL published?

The SDWA, as amended in 1996, directs EPA to publish a CCL every five years. The agency
published the first CCL (CCL 1) in March 1998, the second CCL (CCL 2) in February 2005, the
third CCL (CCL 3) in October 2009, and the fourth CCL (CCL 4) in November 2016.

What contaminants are included on the CCL 5?

The chemical and microbial contaminants included on CCL 5 are listed in the tables below.

Final Drinking Water Contaminant Candidate List 5- Chemical Contaminants

Chemical Name

CASRN1

DTXSID2

1,2,3-Trichloropropane

96-18-4

DTXSID9021390

1,4-Dioxane

123-91-1

DTXSID4020533

17-alpha ethynyl estradiol

57-63-6

DTXSID5020576

2,4-Dinitrophenol

51-28-5

DTXSID0020523

2-Aminotoluene

95-53-4

DTXSID 1026164

oEPA

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Chemical Name

CASRN1

DTXSID2

2-Hydroxyatrazine

2163-68-0

DTXSID6037807

6-Chloro-l,3,5-triazine-2,4-diamine

3397-62-4

DTXSID 1037806

Acephate

30560-19-1

DTXSID8023 846

Acrolein

107-02-8

DTXSID5020023

alpha-Hexachlorocyclohexane

319-84-6

DTXSID2020684

Anthraquinone

84-65-1

DTXSID3020095

Bensulide

741-58-2

DTXSID9032329

Bisphenol A

80-05-7

DTXSID7020182

Boron

7440-42-8

DTXSID3023922

Bromoxynil

1689-84-5

DTXSID3 022162

Carbaryl

63-25-2

DTXSID9020247

Carbendazim (MBC)

10605-21-7

DTXSID4024729

Chlordecone (Kepone)

143-50-0

DTXSID 1020770

Chlorpyrifos

2921-88-2

DTXSID4020458

Cobalt

7440-48-4

DTXSID 1031040

Cyanotoxins3

Multiple

Multiple

Deethylatrazine

6190-65-4

DTXSID5037494

Desisopropyl atrazine

1007-28-9

DTXSID0037495

Desvenlafaxine

93413-62-8

DTXSID40869118

Diazinon

333-41-5

DTXSID9020407

Dicrotophos

141-66-2

DTXSID9023914

Dieldrin

60-57-1

DTXSID9020453

Dimethoate

60-51-5

DTXSID7020479

Disinfection byproducts (DBPs)4

Multiple

Multiple

Diuron

330-54-1

DTXSID0020446

Ethalfluralin

55283-68-6

DTXSID8032386

Ethoprop

13194-48-4

DTXSID4032611

Fipronil

120068-37-3

DTXSID4034609

Fluconazole

86386-73-4

DTXSID3 020627

Flufenacet

142459-58-3

DTXSID2032552

Fluometuron

2164-17-2

DTXSID8020628

Iprodione

36734-19-7

DTXSID3024154

Lithium

7439-93-2

DTXSID5036761

Malathion

121-75-5

DTXSID4020791

Manganese

7439-96-5

DTXSID2024169

Methomyl

16752-77-5

DTXSID 1022267

Methyl tert-butyl ether (MTBE)

1634-04-4

DTXSID3020833

Methylmercury

22967-92-6

DTXSID9024198

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Chemical Name

CASRN1

DTXSID2

Molybdenum

7439-98-7

DTXSID 1024207

Nonylphenol

25154-52-3

DTXSID3021857

Norflurazon

27314-13-2

DTXSID8024234

Oxyfluorfen

42874-03-3

DTXSID7024241

Per- and polyfluoroalkyl substances
(PFAS)5

Multiple

Multiple

Permethrin

52645-53-1

DTXSID8022292

Phorate

298-02-2

DTXSID4032459

Phosmet

732-11-6

DTXSID5024261

Phostebupirim

96182-53-5

DTXSID 1032482

Profenofos

41198-08-7

DTXSID3032464

Propachlor

1918-16-7

DTXSID4024274

Propanil

709-98-8

DTXSID8022111

Propargite

2312-35-8

DTXSID4024276

Propazine

139-40-2

DTXSID3021196

Propoxur

114-26-1

DTXSID7021948

Quinoline

91-22-5

DTXSID 1021798

Tebuconazole

107534-96-3

DTXSID9032113

Terbufos

13071-79-9

DTXSID2022254

Thiamethoxam

153719-23-4

DTXSID2034962

Tri-allate

2303-17-5

DTXSID5024344

Tribufos

78-48-8

DTXSID 1024174

Tributyl phosphate

126-73-8

DTXSID3021986

Trimethylbenzene (1,2,4-)

95-63-6

DTXSID6021402

Tris(2-chloroethyl) phosphate (TCEP)

115-96-8

DTXSID5021411

Tungsten

7440-33-7

DTXSID8052481

Vanadium

7440-62-2

DTXSID2040282

1	Chemical Abstracts Service Registry Number (CASRN) is a unique identifier assigned by the Chemical Abstracts Service (a
division of the American Chemical Society) to every chemical substance (organic and inorganic compounds, polymers,
elements, nuclear particles, etc.) in the open scientific literature. It contains up to 10 digits, separated by hyphens into three
parts.

2	Distributed Structure Searchable Toxicity Substance Identifiers (DTXSID) is a unique substance identifier used in EPA's
CompTox Chemicals database, where a substance can be any single chemical, mixture or polymer.

3	Toxins naturally produced and released by some species of cyanobacteria (previously known as "blue-green algae"). The group
of cyanotoxins includes, but is not limited to: anatoxin-a, cylindrospermopsin, microcystins, and saxitoxin.

4	This group includes 23 unregulated DBPs.

5	For the purpose of CCL 5, the structural definition of per- and polyfluoroalkyl substances (PFAS) includes chemicals that
contain at least one of these three structures (except for PFOA and PFOS which are already in the regulatory process):

1.	R-(CF2)-CF(R')R", where both the CF2 and CF moieties are saturated carbons, and none of the R groups can be
hydrogen

2.	R-CF20CF2-R', where both the CF2 moieties are saturated carbons, and none of the R groups can be hydrogen

3.	CF3C(CF3)RR', where all the carbons are saturated, and none of the R groups can be hydrogen

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Final Drinking Water Contaminant Candidate List 5- Microbial Contaminants

Microbial Name

Type of Microorganism

Adenovirus

Virus

Caliciviruses

Virus

Campylobacter jejuni

Bacteria

Escherichia coli (0157)

Bacteria

Enteroviruses

Virus

Helicobacter pylori

Bacteria

Legionella pneumophila

Bacteria

Mycobacterium abscessus

Bacteria

Mycobacterium avium

Bacteria

Naegleria fowleri

Protozoa

Pseudomonas aeruginosa

Bacteria

Shigella sonnei

Bacteria

What approach did EPA use to list contaminants on the CCL 5?

EPA considered the best available health effects information and occurrence data to evaluate
contaminants.

In selecting contaminants for the CCL 5, EPA:

1.	Followed the stepwise process used in developing the CCL 3 and CCL 4, which was
based on expert input and recommendations from the Science Advisory Board (SAB),
National Research Council (NRC), and National Drinking Water Advisory
Committee (NDWAC). This process consists of building a broad universe of
contaminants, screening the universe of contaminants, and classifying the
contaminants to select the CCL.

2.	Implemented improvements to the CCL process to better identify, screen, and classify
potential drinking water chemical contaminants for CCL 5. EPA's approach utilized
the best available data to characterize the occurrence and adverse health risks a
contaminant may pose from potential drinking water exposure.

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3. Sought and evaluated nominations from the public for additional contaminants to
consider in October 2018.

4.	Evaluated any new available data for those contaminants with previous negative
regulatory determinations from previous CCLs for potential inclusion on the CCL 5.

5.	Considered public and Science Advisory Board (SAB) recommendations and
evaluated the data and information provided by commenters in determining the Final
CCL 5.

How did EPA consider public comments on the Draft CCL 5?

EPA published the Draft CCL 5 in & Federal Register (FR) notice on July 19, 2021. In this FR
notice, EPA solicited input from the public and specifically requested comments on: (1)
contaminants that EPA selected for the Draft CCL 5 and any supporting data that could assist
with developing the Final CCL 5; (2) existing data that EPA obtained and evaluated for
developing the Draft CCL 5; and (3) improvements that EPA implemented for developing the
Draft CCL 5.

EPA reviewed all the comments received on the Draft CCL 5 and evaluated information
provided by commenters when finalizing the CCL 5 for publication.

What changes were made from the Draft CCL 5 to the Final CCL 5?

Based on EPA's review of data and information collected during the comment period and new
data available, EPA made the following changes from the Draft to the Final CCL 5:

•	EPA updated the CCL 5 Technical Support documents to include recommendations from
public comments and SAB recommendations.

•	EPA revised and expanded the definition for PFAS to include additional PFAS
substructures such as PFAS that are ethers, highly branched, persistent in water, and
known to occur in drinking water and/or source water.

What happens to contaminants on the Draft CCL 5?

The purpose of the Draft CCL 5 was to present the list of contaminants and seek comment on the
list and the various aspects of its development. EPA sought comments on the process used to
identify the Draft CCL 5, the data used in the process, and on the individual contaminants

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included on the Draft CCL 5. All comments submitted were considered in determining the Final
CCL 5.

What happens to contaminants on the Final CCL 5?

EPA will evaluate all the contaminants on the CCL 5 to determine which contaminants have
sufficient information to allow the Agency to make a regulatory determination. For those
contaminants that lack sufficient information, EPA will encourage research to provide the
information needed to determine whether to regulate the contaminant.

Does the CCL impose any requirements on public water systems?

No. Publishing a CCL does not impose any requirements on public water systems. If EPA
decided to regulate a contaminant on the list in the future, the Agency would start a separate
rulemaking process with opportunity for public comment.

What is a regulatory determination?

A regulatory determination is a formal decision on whether EPA should initiate a process to
develop a national primary drinking water regulation for a specific contaminant. The law
requires that EPA make regulatory determinations for at least five contaminants from the most
recent CCL, every five years.

Where can Ifind more information about this notice and the CCL?

For more information on the Fifth CCL, please visit the EPA website,

https://www.epa.eov/ccl/contaminant-candidate4ist-5-ccl-5. For general information
on the CCL, please visit EPA's website, https://www.epa.gov/ccl.

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