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SNAP

SIGNIFICANT NEW ALTERNATIVES POLICY

July 21, 2017

www.epa.gov/ozone/snap

FACT SHEET

Protection of Stratospheric Ozone: New Listings for the Significant
New Alternatives Policy Program in Refrigeration & Air
Conditioning and Solvent Cleaning Sectors

Action Listing New Acceptable
Substitutes

Section 612 of the Clean Air Act requires EPA to
evaluate alternatives to ozone-depleting substances.

EPA's Significant New Alternatives Policy (SNAP)
program reviews substitutes in a comparative risk
framework, using the same risk criteria for all SNAP
decisions. Section 612 requires EPA to list as
acceptable those substitutes that do not present a
significantly greater risk to human health and the
environment as compared with other substitutes that
are currently or potentially available.

This determination of acceptability (Notice 33) expands
EPA's SNAP list of acceptable substitutes, providing
industry with more options in the refrigeration and air
conditioning and cleaning solvents sectors.

SUMMARY OF ACCEPTABLE SUBSTITUTES

Notice 33

What is included in the Notice?

•	Twelve additional acceptable substitutes that
reduce overall risk to human health and
environment

Which industrial sectors are included?

•	Refrigeration & Air Conditioning

•	Cleaning Solvents

What health and environmental impacts of

substitutes does EPA evaluate?

•	Atmospheric effects, toxicity, flammability,
occupational and consumer health/safety, local
air quality, and ecosystem effects

End-Use

Substitutes

Refrigeration & Air Conditioning

Cold Storage Warehouses (New & Retrofit)

R-448A, R-449A, R-449B, R-453A

Industrial Process Refrigeration (New & Retrofit)

R-448A, R-449A, R-449B, R-453A, R-458A

Non-Mechanical Heat Transfer Systems (New & Retrofit)

HFE-7300 (l,l,l,2,2,3,4,5,5,5-decafluoro-3-
methoxy-4-(trifluoromethyl)pentane)

Refrigerated Transport- Refrigerated Trucks and Trailers (New & Retrofit)

R-452A, R-452C

Retail Food Refrigeration - Remote Condensing Units (New & Retrofit)

R-407H, R-442A, R-452A, R-452C, R-453A, R-458A

Residential Dehumidifiers (New & Retrofit)

R-513A

Residential and Light Commercial Air Conditioning and Heat Pumps (Retrofit)

HFC-134a, R-458A

Cleaning Solvents

Electronics Cleaning, Metals Cleaning, Precision Cleaning

HFE-7300 (1,1,1,2,2,3,4,5,5,5-decafluoro-3-
methoxy-4-(trifluoromethyl)pentane)

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