United States Environmental Protection Agency	Office of Research and Development

National Exposure Research Laboratory
Research Abstract

Government Performance Results Act (GPRA) Goal #4
Annual Performance Measure #230

Significant Research Findings:

Joint ORD/OPP Workshop on the Analysis of Population
Genetics of Invertebrates in Agroecosystems

Scientific	The U.S. EPA is constantly looking for new and innovative ways to improve

Problem and	ecological risk assessment and regulation of pesticides. The field of population

Policy Issues	genetics is concerned with the question of how genes and traits move through

populations of species in time and space. As such, it has application to questions
of pesticide regulation, environmental impact assessment, and environmental
monitoring. However, these tools have not historically played a large role in risk
assessments performed by EPA. Establishment of a dialogue between risk
assessors and researchers active in the field of population genetics is a necessary
first step to increasing the utility of these tools within the Agency.

Research	A workshop was organized that included representatives from academia, the U.S.

Approach	Department of Agriculture (USDA), two divisions of EPA's Office of Pesticide

Programs (OPP), and two laboratories within EPA's Office of Research and
Development (ORD). Organization of the 1/4-day workshop was driven by three
fundamental goals. First, it was to provide a forum to educate environmental
researchers about the challenges confronted by pesticide risk assessors and
regulators and to convey the key questions that need to be answered. Second, it
was to provide an opportunity for risk assessors to be educated on population
genetic concepts and how tools that have been developed in this field might be
used to solve key environmental questions. Finally, an intended outcome was to
evaluate the usefulness of existing EPA research in population genetics and
develop a prioritized list of future research priorities that could be pursued through
intramural research, extramural funding programs, or collaborative agreements
with other agencies.

Results and	A key conclusion of the workshop was that population genetic methods would

Impact	have great value in development of long-term ecosystem monitoring tools. EPA is

in need of systematic, unbiased ecosystem monitoring programs to evaluate the
environmental results of regulatory programs. A well structured, long-term
research vision that identifies incremental improvements in the program was
recommended. Pesticide effects on nontarget organisms are a key concern of OPP
and development of genetic methods to directly assess population impacts and to
extrapolate impacts across species would be welcomed.

Research
Collaboration
and Research

The workshop was jointly organized by ORD (Ecological Exposure Research
Division of NERL and the Western Ecology Division of the National Health and
Environmental Effects Research Laboratory) and OPP (Environmental Fate and


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Products	Effects Division and the Biopesticides and Pollution Prevention Division). Invited

participants came from academia (University of California at Davis, Washington
State University, Vanderbilt University, University of Idaho, and University of
Maryland), and the USDA. A summary report for the workshop is forthcoming.

Future Research Population genetics research at EPA is currently being conducted by multiple

laboratories at ORD, as well as in academia and other government agencies. This
workshop served to focus development of future research activities to best serve
the needs of pesticide risk assessment. The workshop formed the basis for
continued dialog and feedback between regulators and researchers that will result
in more effective research products.

Questions and inquiries can be directed to:

Mark J. Bagley, Ph.D.

U.S. EPA, Office of Research and Development
National Exposure Research Laboratory
26 W. Martin Luther King Dr.

Cincinnati, OH 45268
Phone:513/569-7455
E-mail: bagley.mark@epa.gov

Funding for this workshop was through the U.S. EPA's Office of Research and
Development, National Exposure Research Laboratory, Ecological Exposure
Research Division.

Contacts for

Additional

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