Final Risk Evaluation for N-Methylpyrrolidone (NMP), Systematic Review Supplemental File: Data Quality Evaluation of Environmental Release and Occupational Exposure Data CASRN: 872-50-4


v>EPA

United States

Environmental Protection Agency

Office of Chemical Safety and

Pollution Prevention

Final Risk Evaluation for
n-Methylpyrrolidone

Systematic Review Supplemental File:

Data Quality Evaluation of Environmental Release
and Occupational Exposure Data

CASRN: 872-50-4

December 2020

-------
This document is a compilation of tables for the data extraction and evaluation for
N-Methylpyrrolidone (NMP). Each table shows the data point or set or information
element that was extracted and evaluated from a data source in accordance with Appendix D
of the Application of Systematic Review in TSCA Risk Evaluations. If the source contains more
than one data set or information element, the review provides an overall confidence score for
each data set or information element that is found in the source. Therefore, it is possible
that a source may have more than one overall quality/confidence score.

Table of Contents

Page

Releases to the Environment	3

Occupational Exposure	69

Facility	491

Explanatory Notes

These explanatory notes provide context to understand the short comments in the data evaluation tables.

Domain

Metric

Description of Comments Field

Reliability

Methodology

Indicates the sampling/analytical methodology, estimation method, or
type of publication

Repre sentativene ss

Geographic Scope

Indicates the country of the study, publication, or underlying data

Applicability

Indicates whether the data are for a condition of use within scope of the
Risk Evaluation

Temporal Representativeness

Provides the year of study, publication, or underlying data

Sample Size

Describes the distribution of the sample or underlying data

Accessibility / Clarity

Metadata Completeness

Describes the completeness of the metadata

Variability and Uncertainty

Metadata Completeness

Indicates if study or publication addresses variability and uncertainty of
the data or information

Page 2 of 691

-------
Releases to the Environment

Page 3 of 691

-------
Source Citation: Solomon, G. M., Morse, E. P., Garbo, M. J., Milton, D. K.. 1996. Stillbirth after occupational exposure to N-

methyl-2-pyrrolidone: A case report and review of the literature. Journal of Occupational and Environmental Medicine.
Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3043623

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Environmental Media:

Release or Emission Factor:

Daily Release Quantity (kg/day):

Number of Sites:

Use

laboratory
Laboratory waste
hazardous waste
hazardous waste
100 percent released
1 L/day
1.0

EVALUATION

Domain

Metric

Rating MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium X 1 2 From an industry contact

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope High x 1 1

Applicability High x 2 2

Temporal Representativeness Low x 2 6

Sample Size Medium x 1 2

Use is in scope

1996 - more than 20 years old
Information is from one source

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

Medium

1.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 4 of 691

-------
Source Citation: Kim, B. R., Kalis, E. M., Dewulf, T., Andrews, K. M.. 2000. Henry's law constants for paint solvents and their implications on

volatile organic compound emissions from automotive painting. Water Environment Research.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3578170

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Disposal /Treatment Method:
Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)
Number of Sites:

Use

Painting

During painting, overspray paint materials are captured in continuously
recirculating scrubber water and stored in a sludge pit. Periodically or
continually (depending on operating conditions of an assembly plant),
captured paint material (paint sludge) is separated from scrubber water
and sent to a landfill. Spent scrubber water that contains VOCs is peri-
odically discharged to a municipal wastewater treatment plant. At some
assembly plants, a portion of VOCs in the exhaust air is captured and
destroyed using vapor-phase adsorption followed by thermal oxidation
before the air is emitted to the atmosphere.

Wastewater, incineration

80 percent of the PV (9700 kg/yr) is released in scrubber wastewater
Measured

7700 kg/yr in scrubber wastewater
1.0

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium x 1 2 Does not cover all releases at the site

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Use is in scope

Metric 4:

Temporal Representativeness

Low

1996

Metric 5:

Sample Size

High

Statistical distribution of samples is fully characterized. Sam

pie size is sufficiently representative (11 samples)

Continued on next page

Page 5 of 691

-------
— continued from previous page

Source Citation:	Kim, B. R., Kalis, E. M., Dewulf, T., Andrews, K. M.. 2000. Henry's law constants for paint solvents and their implications

on volatile organic compound emissions from automotive painting. Water Environment Research.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3578170

EVALUATION







Domain Metric

Rating

MWF*

Score Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

X 1

2 Lacks release frequency

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

X 1

2 limited discussion

Overall Quality Determination^

Medium



1.8



* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 6 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Disposal /Treatment Method:
Environmental Media:

Release Estimation Method:
Annual Release Quantity (kg/yr)

Processing

Formulation of adhesive

Wash water from formulation equipment will be re-used in subsequent
batches where possible. Otherwise, it will be treated on site and sludge
disposed of to landfill. 50 percent of the wash water will be re-used
in subsequent batches and the remainder released into the sewer. An
estimated 100 kg of the notified polymer will be lost to landfill as residues
in the empty import drums each year.

WWT

Landfill, Water

Estimated by formulation and use company

For polymer in formulation (polymer is 35 percent ; NMP is 5 percent
) = 45 kg/yr (landfill from WWT); 5 kg/yr (water from WWT); 100
kg/yr (landfill from empty drums)

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Likely to cover all releases

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1

High	x 2

Medium	x 2

Low	x 1

Australia

Use is in scope

2001

Not characterized

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 data include all associated metadata

Domain 4: Variability and Uncertainty

Continued on next page

Page 7 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3978357

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Metric 7: Metadata Completeness

Low

X 1 3 No discussion



Overall Quality Determination^

Medium

1.8





* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 8 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Disposal /Treatment Method:
Environmental Media:

Release Estimation Method:
Annual Release Quantity (kg/yr)

Use

Spray application of adhesive

The notifier estimates that approximately one third of the formulation
will be lost as overspray. Of this, 50 percent will be trapped in the
spray both water reservoir and 50 percent will be removed by the scrub-
ber unit. All other dry wastes generated during the application of the
basecoat, including the waste obtained from the periodic cleaning of
scrubber baffles and filters will also be disposed of in landfill.

WWT

Landfill, Water

Estimated by formulation and use company

For polymer in formulation (polymer is 35 percent ; NMP is 5 percent )
= 6.6 tonnes/yr (WWT)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Likley to cover all releases

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Australia

Metric 3:

Applicability

High

x 2

2

Use is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2001

Metric 5:

Sample Size

Low

x 1

3

Not characterized

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 data include all associated metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	x 1	3 No discussion

Continued on next page

Page 9 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3978357

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 10 of 691

-------
Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3982074

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Release or Emission Factor:

Daily Release Quantity (kg/day):

Number of Sites:

Use

immersion degreasing
solvent dragout
dragout

1.94 grams/lb of parts cleaned
912 g/day (114 g/hr for 8 hrs)
1.0

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

may not cover all release sources at the site

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

Cleaning is included in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1993

Metric 5:

Sample Size

Low

x 1

3

characterized by no statistics.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks release frequency

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

Low

x 1

3

The report does not address variability or uncertainty.

Overall Quality Determination^

Medium

2.1

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 11 of 691

-------
Source Citation: Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3982074

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Annual Release Quantity (kg/yr):

Number of Sites:

Use

immersion degreasing

Evaporative losses during operation. Total bath solvent surface area is

10 in. x 24 in.

air

10.96 grams/hour
1.0

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 may not cover all release sources at the site

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Cleaning is included in scope

Metric 4:

Temporal Representativeness

Low

1993

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Medium

Lacks release frequency

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

The report does not address variability or uncertainty.

Overall Quality Determination^

Medium

2.1

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 12 of 691

-------
Source Citation: Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3828838

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release or Emission Factor:

All
all

Releases to air from various generic unit operations, valves and other
attachments. Residuals in drums and tanks
air, uncertain

Average emission factors for unit operations are in Table 7.1. Emis-
sion factors for fugitive emissions from valves, etc. in Table 7.2. Drum
residual LF in Table 7.3.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium x 1 2 OECD

Medium X 2 4 Generic information that can be applied to in-scope uses

High x 2 2 2011

Low X 1 3 characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 well characterized

Overall Quality Determination^

Medium

1.7

* MWF = Metric Weighting Factor

Page 13 of 691

-------
Source Citation:	2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3860493

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Environmental Media:

Release or Emission Factor:

Release Estimation Method:

Use

petrochemical processing aid?
wastewater effluent
POTW

0, 33.7, 66.3 ug NMP/L wastewater
3 measurements taken at petrochemical plant

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Does not cover all releases at the site

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1996-1997

Metric 5:

Sample Size

High

x 1

1

3 samples, all results given

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Low

x 1

3

Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

Low

x 1

3

No discussion

Overall Quality Determination^

Medium

2.0

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 14 of 691

-------
Source Citation:	Atsdr,. 2015. Health consultation: Review of air quality data: Intel Corporation " New Mexico facility: Rio Rancho, Sandoval

County, New Mexico: EPA facility ID: NMD000609339, Part 2.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	3970460

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release Estimation Method:
Annual Release Quantity (kg/yr):

Use

electronics - photoresist remover?

unknown - based on company process operations, NMP was likely used as
a photoresist remover in the 1990s and the facility switched to a different
solvent in the 2000s
Air

TRI 1987-2013

>9,000 lb in 1995; 0 pounds in 2013

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Does not cover all releases at the site

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1987-2013

Metric 5:

Sample Size

Medium

x 1

2

range provided in bar graph

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Low

x 1

3

Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^

Medium

2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 15 of 691

-------
Source Citation:	Nicnas,. 1997. Full public report: Polymer in byk-410.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3978356

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release or Emission Factor:

Release Estimation Method:

Annual Release Quantity (kg/yr):

Processing

coating /paint formulation

release of polymer-NMP coating additive during formulation is estimated
to be no more than 2 percent total. Incorporates all sources of release,
all

2 percent

information from one formulation company

55 kg/yr of polymer_NMP soln based on annual use rate of 2750 kg.yr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Likely to cover all releases

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1

High	x 2

Low	x 2

Low	x 1

2	Australia

2	in scope
6	1997

3	characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 No discussion

Overall Quality Determination^

Medium

2.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 16 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Nicnas,. 1998. Full public report: Copolymer in foraperle 321.
Releases to the Environment; Environmental Release Data;
3978358

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release or Emission Factor:
Release Estimation Method:
Annual Release Quantity (kg/yr)

Use

Coating /additive in Papermaking

release to the environment may potentially occur from: leaking storage
containers (less than 2 percent ); accidental spills (less than 1 percent
); during application (less than 10 percent ) and disposal of residual
material in containers (less than 5 percent ). The worst case total of
20 percent released during the application to paper, corresponds to a
maximum of 500 kg per annum at the maximum rate of import,
all

10 percent

information from one papermaking company

500 kg/yr of polymer-NMP soln based on annual import rate of 2,500
kg

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Likely to cover all releases

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Australia

Metric 3:

Applicability

High

x 2

2

This was not identified as a use by EPA, but no uses are ex-











cluded from scope. May be applicable to coating OES?

Metric 4:

Temporal Representativeness

Low

x 2

6

1998

Metric 5:

Sample Size

Low

x 1

3

characterized by no statistics.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Release data include release media and source, but not fre-











quency of release

Continued on next page

Page 17 of 691

-------
— continued from previous page

Source Citation: Nicnas,. 1998. Full public report: Copolymer in foraperle 321.
Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3978358

EVALUATION

Domain Metric

Rating MWF*

Score

Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low X 1

3 No discussion



Overall Quality Determination^

Medium

2.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 18 of 691

-------
Source Citation:	Nicnas,. 1998. Full public report: Copolymer in foraperle 321.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID	3978358

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Use

architectural (concrete) coating

Release to the environment resulting from the use of the polymer as a
concrete coating may occur to the sewer (washing of tools used to apply
formulations containing the notified chemical), or to landfill (disposal of
residual quantities of the formulations within used containers). Over-
spray or splatter from rollers or brushes (These releases are likely to
remain where they fall, mainly on the ground.)

Sewer; landfill

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

Likely to cover all releases

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium
High
Low
N/A

X 1

x 2
x 2

2
2
6

N/A

Australia
in scope
1998

This metric is not applicable to this data element

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Release data include release media and source, but not fre-
quency of release

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

No discussion

Overall Quality Determination^

Medium



2.0



Continued on next page

Page 19 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Nicnas,. 1998. Full public report: Copolymer in foraperle 321.
Releases to the Environment; Environmental Release Data;
3978358



EVALUATION





Domain

Metric Rating MWF* Score

Comments





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 20 of 691

-------
Source Citation:	Erg,. 2000. Preferred and alternative methods for estimating air emissions from paint and ink manufacturing facilities.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982076

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release or Emission Factor:

Release Estimation Method:

P2 Control & percent Efficiency:

Processing

Paint and ink formulation

material loading, heat-up losses, equipment leaks, spills, surface evapo-
ration, liquid material storage, WWT
Fugitive air emissions from the listed release sources
Provides examples of calculating emissions based on emission factors
from AP-42, source-specific models, and mass balances.

AP-42 and models (not NMP-specific)

Removal equipment available for treating VOC-containing air streams
includes recovery devices (i.e., carbon adsorption, absorption, and con-
densation) and combustion devices (i.e., thermal incinerators, catalytic
incinerators, and industrial boilers and process heaters). Control effi-
ciencies for this equipment can range from 50 to 99 percent, but are
most typically greater than 95 percent (EIIP, 2000). Carbon adsorbers,
absorbers (scrubbers), condensers, and catalytic incinerators are gener-
ally not appropriate for paint and ink manufacturing facilities. Industrial
and process heaters are capable of effectively treating the types and lev-
els of VOCs generated by the paint and ink industry but are found in
few, if any, paint and ink manufacturing facilities (EPA, 1992a).

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

From trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2000

Metric 5:

Sample Size

N/A



N/A

This metric is not applicable to this data element

Continued on next page

Page 21 of 691

-------
— continued from previous page

Source Citation:	Erg,. 2000. Preferred and alternative methods for estimating air emissions from paint and ink manufacturing facilities.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982076

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

well characterized

Overall Quality Determination^

High



1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 22 of 691

-------
Source Citation: Mo, D. N. R.. 2001. State of Missouri toxics release inventory: Summary report: 1999 data.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3982077

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Release Estimation Method:

Annual Release Quantity (kg/yr):

Use

paints and adhesives used in the transportation equipment MFG sector

air emissions

Air

1999 TRI data for the state of Missouri
83,500 kg/yr (in 1999 in Missouri)

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Expected to cover all releases

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

Medium

1999

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Low

Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

No discussion

Overall Quality Determination^

Medium

1.9

* MWF = Metric Weighting Factor

Page 23 of 691

-------
Source Citation: Mo, D. N. R.. 2001. State of Missouri toxics release inventory: Summary report: 1999 data.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3982077

EXTRACTION

Parameter Data

Life Cycle Description (Subcategory of Use):

Release Source:

Environmental Media:

Release Estimation Method:
Annual Release Quantity (kg/yr)

Unknown - emission data provide per company name (based on names,
may include: wire coating, car painting, lab, solvent mfg, cement coat-
ing)

unknown - TRI data

Air, POTW, WWT, landfill, energy recovery

1999 TRI data for the state of Missouri

see App C and G for site specific TRI emissions

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Expected to cover all releases

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

High
Medium

x 1
x 2

Metric 4: Temporal Representativeness Medium x 2
Metric 5: Sample Size Low x 1

Data may include info on in-scope uses, but cannot be deter-
mined without searching company names

1999

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 No discussion

Overall Quality Determination^

Medium

2.1

* MWF = Metric Weighting Factor

Page 24 of 691

-------
Source Citation:	Technikon, L. L. C.. 2001. Core box cleaner study: Evaporative emission study of specialty systems' solvent FC-47-G1.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982183

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Use

cleaning of casts /molds and hoppers in foundry applications

Release Source:

Environmental Media:
Release or Emission Factor:



Study on the rate of evaporation of cleaning solution containing NMP
at unknown concentration
Fugitive air

0.00004 g of solvent soln/sec (see Fig 12 - 16)

EVALUATION

Domain

Metric

Rating

MWF*

Score Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1 High quality techniques

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
High

X 1

x 2
x 2
x 1

1	US

2	in scope

4 2001

1 Fully characterized with multiple figures and charts

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 well characterized

Overall Quality Determination^

High



1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 25 of 691

-------
Source Citation: Chemistry Industry Association of, Canada. 2017. All substances emissions for 2012 and projections for 2015.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3982361

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Annual Release Quantity (kg/yr)

Use

Assumed = Paint formulation; Chemical Formulation

Source lists NMP emissions from sites in Canada. Source does not list

the operations that occur at the sites. Assumed life cycle descriptions

based on the names of the facilities.

Air

0.1 tonnes/yr (2012)

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Low X 1 3 Methodology is not specified

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope Medium x 1 2

Applicability Medium x 2 4

Temporal Representativeness High x 2 2

Sample Size Low x 1 3

Canada

The operations at these sites are not characterized. Assumed
to likely be in scope, but unknown,

2012

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 The release data study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

2.2

* MWF = Metric Weighting Factor

Page 26 of 691

-------
Source Citation: Chemistry Industry Association of, Canada. 2017. All substances emissions for 2011 and projections for 2014.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3982362

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Environmental Media:

Annual Release Quantity (kg/yr)

Use

Assumed = Paint formulation; Chemical Formulation

Source lists NMP emissions from sites in Canada. Source does not list

the operations that occur at the sites. Assumed life cycle descriptions

based on the names of the facilities.

Air

0.05 tonnes/yr (2011)

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Low X 1 3 Methodology is not specified

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope Medium x 1 2

Applicability Medium x 2 4

Temporal Representativeness High x 2 2

Sample Size Low x 1 3

Canada

The operations at these sites are not characterized. Assumed

to likely be in scope, but unknown,

2011

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 The release data study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

2.2

* MWF = Metric Weighting Factor

Page 27 of 691

-------
Source Citation: Turner, S. L., McCrillis, R. C.. 2017. Evaluation of alternative chemical strippers on wood furniture coatings.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 3986887

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Environmental Media:

Release or Emission Factor:

Release Estimation Method:

Use

Paint stripper

VOC emissions during stripping
fugitive air

158.94 to 263.74 g VOC /m2 substrate surface

VOC from stripping solutions containing NMP (solutions 2, 3, 4 in the
study)

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 The release data methodology is known or expected to be accu-

rate (e.g., trusted source) but may not cover all release sources
at the site

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

Low

no date

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Low

Release data include release media but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

The release data study does not address variability or uncer-

tainty.

Overall Quality Determination^ Medium 2.2

* MWF = Metric Weighting Factor

Page 28 of 691

-------
Source Citation: Campbell, H. L., Striebig, B. A.. 1999. Evaluation of N-methylpyrrolidone and its oxidative products toxicity utilizing

the microtox assay. Environmental Science and Technology.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3566019

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

P2 Control & percent Efficiency:

All
all

Study on the toxicity of byproducts from the oxidation of NMP in
wastewater.

Countercurrent wet scrubber was utilized to transfer the NMP vapor to
the aqueous phase. The scrubber utilized water as the scrubbing liquor
and removed greater than 97 percent of the NMP from the exhaust air
stream at the facility

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope High x 1 1

Applicability Medium x 2 4

Temporal Representativeness Medium x 2 4

Sample Size Low x 1 3

Applicable to in-scope uses; but, information is on toxicity
which is not used by engineering assessors (is used by exposure
assessors)

1999

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1 2

limited discussion

Continued on next page

Page 29 of 691

-------
— continued from previous page

Source Citation:	Campbell, H. L.,Striebig, B. A.. 1999. Evaluation of N-methylpyrrolidone and its oxidative products toxicity utilizing the

microtox assay. Environmental Science and Technology.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3566019

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 30 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Estimation Method:

Annual Release Quantity (kg/yr):

Number of Sites:

Processing

paint and coating formulation
releases from Envirofacts search
see release rates in report
1.0

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Low X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2008-present

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

** Consistent with our Application of Systematic Review in TSCA Risk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),

EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 31 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Photographic Film, Paper, Plate, and Chemical Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 32 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): All Other MiscellaneousC hemical Product and Preparation Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 33 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Processing

Plastic Material and Resin Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 34 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Processing

All Other Miscellaneous Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 35 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Cement Manufacturing see release

Annual Release Quantity (kg/yr): rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 36 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Disposal

Hazardous Waste Treatment and Disposal

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 37 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Battery Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 38 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): All Other Basic Organic Chemical Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 39 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Distribution

Other Chemical and Allied Products Merchant Wholesalers

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 40 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Use

Semiconductor and Related Device Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 41 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Pesticide and Other Agricultural Chemical Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 42 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Adhesive Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 43 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Other Miscellaneous General Purpose Machinery Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 44 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Disposal

All Other Miscellaneous Waste Management Services

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 45 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Use

Motor Vehicle Seating and Interior Trim Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 46 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Fabric Coating Mills

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 47 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Unlaminated Plastics Film and Sheet (except Packaging) Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 48 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Processing

Other Communication and Energy Wire Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 49 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Other Electronic Component Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 50 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Processing

Medicinal and Botanical Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 51 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Printing Ink Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 52 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Ophthalmic Goods Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 53 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Processing

Polish and Other Sanitation Good Manufacturing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 54 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Pharmaceutical Preparation Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1 3 The release data methodology is not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

Metric 3: Applicability

High

in scope

Metric 4: Temporal Representativeness

High

2008-present

Metric 5: Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

No discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 55 of 691

-------
Source Citation: 2017. Pollution prevention search results, envirofacts database.

Type of Data Source Releases to the Environment; Environmental Release Data;
Hero ID 3860453

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Annual Release Quantity (kg/yr):

Number of Sites:

Use

Leather and Hide Tanning and Finishing

see release rates in report

1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 56 of 691

-------
Source Citation:

2017. Pollution prevention search results, envirofacts database.

Type of Data Source

Releases to the Environment; Environmental Release Data;

Hero ID

3860453

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Urethane and Other Foam Product (except Polystyrene) Manufacturing

Annual Release Quantity (kg/yr): see release rates in report

Number of Sites: 1.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The release data methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2008-present

Metric 5:

Sample Size

Low

x 1

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Unacceptable

x 1

has no release media or other information

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

x 1

No discussion

Overall Quality Determination^ Unacceptable 4 Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 57 of 691

-------
Source Citation:	Basf,. 1998. N-methylpyrrolidone(NMP): Biodegradability.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3982075

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Release Source:

Waste Treatment Method:

All
All

Information on the biodegradability of NMP and use of WWT to treat/

remove NMP from wastewaters

WWTP

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium X 1	2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

Medium

X

2

4

Information is not related to a life cycle stage, but is broadly
applicable

Metric 4:

Temporal Representativeness

Low

X

2

6

1998

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 clearly documents its data sources, assessment methods, re-

suits, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion

Overall Quality Determination^

Medium

2.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 58 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Release or Emission Factor:

Annual Release Quantity (kg/yr):

Release Days per Year:

Processing

Paint and coating removers
Paint strippers

Sent to Wastewater treatment
0.07 kg/site-day
2500 - 3770
250.0

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

EPA

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
N/A

X 1

x 2
x 2

1

2
6

N/A

US

Manufacturing in scope
1989

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

No discussion on uncertainty and variability

Overall Quality Determination^

Medium



1.8



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 59 of 691

-------
Source Citation: LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592033

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

P2 Control & percent Efficiency:

Use

Electronics manufacturing - Lithium Ion Battery
Electrode drying process and NMP recovery system.

NMP is recycled for reuse or taken by licensed haulers for off-site recy-
cling. Exhaust from recovery systems may be collected and discharged
to the municipal sewer in compliance with wastewater permit conditions
(and may contain approximately 0.9 percent NMP). Some amount re-
leased to air.

Manufacturers capture vapor driven off by the electrode drying process,
condense the vapor, and either recover or dispose of the liquid. During
the drying process, the NMP solvent is volatilized and the "oven air"
can be captured and conveyed to an NMP recovery system, with up to
approximately 12 percent immediately returned to the coating/drying
system and the remainder sent through the NMP recovery system on or
off site. Description of recovery system provided on pg. 17.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information is from a trade association of manufacturers,
bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2020

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Continued on next page

Page 60 of 691

-------
— continued from previous page

Source Citation:	LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592033

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

No discussion on uncertainty and variability

Overall Quality Determination^

High



1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 61 of 691

-------
Source Citation:	FUJIFILM Holdings America Corporation. 2020. FUJIFILM comments for docket ID # EPA-HQ-OPPT-2019-0236 for

CASRN 872-50-4, n-methylpyrrolidone (NMP).

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592030

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Processing

Formulation into solutions for electronics industry
all

off-site recycling (solvent recovery or fuel blending)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2020

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 62 of 691

-------
Source Citation:	Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3986801

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Release or Emission Factor:

Release Estimation Method:

Use

Electronics manufacturing - semiconductors
spin coating
off-site incineration

In the spin coat process, between 1-7 percent of the deposited liquid
remains on the wafer; the remainder is spun off the wafer with 1 percent
remaining in the tool and removed during tool cleaning and the balance
collected via solvent waste drain for off-site disposal
OECD ESD

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information is from OECD, which is a trusted source

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

OECD

Metric 3:

Applicability

High

x 2

2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2

2020

Metric 5:

Sample Size

Medium

x 1

2

Distribution of samples is characterized by a range with uncer-

tain statistics. It is unclear if analysis is representative

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x

1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x

1

2

Some discussion on variability

Overall Quality Determination^

High



1.3





Continued on next

page





Page 63 of 691

-------
— continued from previous page

Source Citation:	Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3986801

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 64 of 691

-------
Source Citation: Intel Corporation. 2020. Comments of Intel to the United States Environmental Protection Agency on the draft Toxic

Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone. EPA-HQ-OPPT-2019-0236-0064.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID 6592034

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Release Source:

Disposal /Treatment Method:

Environmental Media:

Release or Emission Factor:

Annual Release Quantity (kg/yr):
P2 Control & percent Efficiency:

Use

Electronics manufacturing - semiconductors
All releases from 2 semiconductor manufacturing sites
On-site wastewater treatment then discharge to POTW
water

the estimated concentration of NMP from the combined Hillsboro and
Aloha facilities to the receiving body of water would be reduced from
1,995 ug/1 to 619 ug/1.

Hillsboro facility (2015): 510,000 lbs/yr NMP released to POTW; Aloha
facility (2015): 170,000 lbs/yr NMP released to POTW
92 percent of the NMP from the Hillsboro facility will be removed during
onsite wastewater treatment system, and the remaining NMP from the
Hillsboro facility will be reduced by another 92 percent at the POTW.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Release data is provided by the company; company expected to
have accurate accounting of their releases. Reported releases
include all water releases.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

Data from 2015

Metric 5:

Sample Size

Medium

Single data point or range provided. It is unclear if

on wastewater treatment efficiency is representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Release data include release media but no other metadata.

Continued on next page

Page 65 of 691

-------
— continued from previous page

Source Citation:	Intel Corporation. 2020. Comments of Intel to the United States Environmental Protection Agency on the draft Toxic

Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone. EPA-HQ-OPPT-2019-0236-0064.

Type of Data Source Releases to the Environment; Environmental Release Data;

Hero ID	6592034

EVALUATION

Domain Metric

Rating

MWF* Score

Comments



Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1 3

The release data study does not address variability or uncer-
tainty.

Overall Quality Determination^

High

1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 66 of 691

-------
Source Citation:

National Electrical Manufacturers Association. 2020. NMP use in magnet wire. EPA-HQ-OPPT-2019-0236-0047.

Type of Data Source

Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

6592028

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Electronics - magnet wires

Release Source: Emissions consist of evaporation from the NMP bath and from the

cleaned parts removed from the bath. Some NMP vapors may be emit-
ted, for example, during equipment cleaning.

Disposal /Treatment Method: Any vapor emitted during application moves directly into the curing

oven wherein at least 90 percent of the NMP combusts3. Depending on
the type of oven, operating temperatures range from 800 1400F degrees.

Environmental Media: Almost all operating lines now have an incinerator. Any liquid waste

NMP and/or solid waste wet with NMP (paper, plastic, rags, etc.) are
handled in compliance with the Resource Conservation and Recovery
Act (RCRA).

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2020

Metric 5:

Sample Size

Medium

x 1

Incineration efficiency is provided as a single value with uncer-

tain statistics. It is unclear if analysis is representative

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Medium

x 1

Data source for the estimate of NMP destruction is not

fully transparent.

Domain 4: Variability and Uncertainty

Continued on next page

Page 67 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

National Electrical Manufacturers Association. 2020. NMP use in magnet wire. EPA-HQ-OPPT-2019-0236-0047.
Releases to the Environment; Reports for Data or Information Other than Exposure or Release Data;

6592028

EVALUATION

Domain

Metric

Rating MWF* Score Comments



Metric 7; Metadata Completeness

Low X 1 3 The release data study does not address variability or uncer-

tainty.

Overall Quality Determination^

High 1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 68 of 691

-------
Occupational Exposure

Page 69 of 691

-------
Source Citation:	Nishimura, S.,Yasui, H., Miyauchi, H., Kikuchi, Y., Kondo, N., Takebayashi, T.,Tanaka, S.,Mikoshiba, Y.,Omae, K.,Nomiyama,

T.. 2009. A cross-sectional observation of effect of exposure to N-methyl-2-pyrrolidone (NMP) on workers' health. Industrial Health.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	735269

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Use

cleaning of instruments

vapor

Inhalation

0.14-0.26 ppm (mean); 0.8 ppm (max)

70.0

1.0

full-shift

all activities during a day
14

personal
8 hrs

5 days/wk

None of the NMP-exposed workers wore any protective respiratory
devices or clothing. All wore disposable, thin protective gloves
made of polyethylene

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Methodology is explained and seems legitimate

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	X 1	2	Japan

High	X 2	2	Cleaning is included in scope

High	X 2	2	2009

High	X 1	1	Statistical distribution of samples is fully characterized.

Continued on next page

Page 70 of 691

-------
— continued from previous page

Source Citation:	Nishimura, S.,Yasui, H.,Miyauchi, H.,Kikuchi, Y.,Kondo, N.,Takebayashi, T.,Tanaka, S.,Mikoshiba, Y.,Omae, K.,Nomiyama,

T.. 2009. A cross-sectional observation of effect of exposure to N-methyl-2-pyrrolidone (NMP) on workers' health. Industrial
Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	735269

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

X 1

2

Lacks worker actitities and whether its TWA

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 71 of 691

-------
Source Citation:	Haufroid, V., Jaeger, V. K., Jeggli, S., Eisenegger, R., Bernard, A., Friedli, D., Lison, D., Hotz, P.. 2014. Biological monitoring and

health effects of low-level exposure to N-methyl-2-pyrrolidone: a cross-sectional study. International Archives of Occupational and
Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	2654929

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Use

graffiti removal or through other uses of NMP

vapor

Inhalation

0.18 (mean), 0.89 (75th), 2.77 (90th), and 25.83 (Max) mg/m3

91.0

21.0

full-shift

graffiti removal or other activities associated with the life cycle
91

personal
310525 min
varies

Suitable masks, butyl or latex gloves

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 Airborne NMP was determined according to the NIOSH

method.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

Multiple European Countries

Metric 3:

Applicability

High

X

2

2

All described conditions of use are in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006-2011

Metric 5:

Sample Size

High

X

1

1

Statistical distribution of samples is fully characterized.

Domain 3: Accessibility/Clarity

Continued on next page

Page 72 of 691

-------
— continued from previous page

Source Citation:	Haufroid, V.,Jaeger, V. K.,Jeggli, S.,Eisenegger, R.,Bernard, A.,Friedli, D.,Lison, D.,Hotz, P.. 2014. Biological monitoring and

health effects of low-level exposure to N-methyl-2-pyrrolidone: a cross-sectional study. International Archives of Occupational
and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	2654929

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 6: Metadata Completeness

Medium

X 1

2

Lacks worker activities and whether its TWA

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 73 of 691

-------
Source Citation:	Solomon, G. M., Morse, E. P., Garbo, M. J., Milton, D. K.. 1996. Stillbirth after occupational exposure to N-

methyl-2-pyrrolidone: A case report and review of the literature. Journal of Occupational and Environmental Medicine.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3043623

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Number of Workers:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:
PPE:

Use

Laboratory
vapor
Inhalation
0.2 mg/m3

2-hour	short term
15

personal and area

Average of 42 hours each week

3-4	days/wk

LEV over the spectrophotometers, but there was no LEV over the coun-
tertop, on which the patient filtered the NMP

half-face air-purifying respirator, coat, safety goggles, and latex gloves

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

This use is in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1996 - more than 20 years old

Metric 5:

Sample Size

Low

x 1

3

Distribution not characterized

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks worker activities and whether its TWA

Domain 4: Variability and Uncertainty

Continued on next page

Page 74 of 691

-------
— continued from previous page

Source Citation:	Solomon, G. M.,Morse, E. P.,Garbo, M. J.,Milton, D. K.. 1996. Stillbirth after occupational exposure to N-methyl-2-

pyrrolidone: A case report and review of the literature. Journal of Occupational and Environmental Medicine.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3043623

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

High

X 1 1 Discussion on variability and uncertainty of results

Overall Quality Determination^

Medium

2.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 75 of 691

-------
Source Citation:	Belanger, P. L., Coye, M. J.. 1983. Health Hazard Evaluation Report No. HETA-79-129-1350, San Francisco

Newspaper Agency, San Francisco, California.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3101190

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

Printing

particulate

Inhalation

0.12 - 3.29 mg/m3

43.0

1.0

full-shift TWA

personal

5.17 - 7.92 hours

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Sampling or analytical methodology is an approved OSHA or







NIOSH method

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High	x 1	1	US

Medium	x 2	4	in scope, but data is not NMP-specific (i.e., surrogate data)

Low	x 2	6	1983

High	X 1	1	Fully characterized

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Fully characterized

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 Some discussion

Continued on next page

Page 76 of 691

-------
— continued from previous page

Source Citation:	Belanger, P. L.,Coye, M. J.. 1983. Health Hazard Evaluation Report No. HETA-79-129-1350, San Francisco Newspaper

Agency, San Francisco, California.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3101190

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 77 of 691

-------
Source Citation:	Belanger, P. L.,Coye, M. J.. 1983. Health Hazard Evaluation Report No. HETA-79-129-1350, San Francisco Newspaper

Agency, San Francisco, California.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3101190

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

Printing

particulate

Inhalation

0.27 - 0.68 mg/m3

5.0

1.0

partial shift

personal

3.33 - 3.58 hours

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Sampling or analytical methodology is an approved OSHA or







NIOSH method

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High	x 1	1	US

Medium	x 2	4	in scope, but data is not NMP-specific (i.e., surrogate data)

Low	x 2	6	1983

High	X 1	1	Fully characterized

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Fully characterized

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 Some discussion

Continued on next page

Page 78 of 691

-------
— continued from previous page

Source Citation:	Belanger, P. L.,Coye, M. J.. 1983. Health Hazard Evaluation Report No. HETA-79-129-1350, San Francisco Newspaper

Agency, San Francisco, California.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3101190

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 79 of 691

-------
Source Citation:	Bader, M., Rosenberger, W., Rebe, T., Keener, S. A., Brock, T. H., Hemmerling, H. J., Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Use

cleaning of optical and metal parts

vapor

Inhalation

average = 2 mg/m3; max = 2.8 mg/m3
2.0

12-hr TWA

cleaning of optical and metal parts
12

personal
12 hr

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Japan

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2000

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Continued on next page

Page 80 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION







Domain Metric

Rating

MWF* Score

Comments

Metric 7: Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 81 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

graffiti removal

vapor

Inhalation

ranged between 0.03 and 4.52 mg/m3; mean - 1.01 (+ or - 0.89) mg/m3;

peak = 24.6 mg/m3

8-hr TWA; short-term peak

personal

8 hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

1	Well described methods

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness Low	x 2

Metric 5: Sample Size	Medium x 1

2 Sweden

4	Similar to an occupational scenario within the scope of the risk

evaluation
6 1993-2001

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Continued on next page

Page 82 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION







Domain Metric

Rating

MWF* Score

Comments

Metric 7: Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

2.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 83 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Sites:

Worker Activity:

Number of Workers:

Type of Sampling:

PPE:

Processing
adhesive formulation
vapor
Inhalation

average = 3.0 mg/m3
1.0

production area
7

area

cotton working clothes, butyl rubber gloves during the cleaning process
and safety eyeglasses

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Continued on next page

Page 84 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

High

X 1 1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 85 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing
adhesive formulation
vapor
Inhalation

average = 10.7 to 18.0 mg/m3
8hr TWA

manual vessel and fittings cleaning
personal

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

This use is in scope

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium x 1 2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1 1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.6

Continued on next page

Page 86 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 87 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing

adhesive formulation

vapor

Inhalation

0.2 mg/m3

1.0

8hr TWA

bottling and shipping department

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	X 1	1 Discussion on variability and uncertainty of results

Continued on next page

Page 88 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 89 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	adhesive formulation

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	0.9 to 2.8 mg/m3

Number of Samples:	3.0

Type of Measurement or Method:	8hr TWA

Worker Activity:	Bottling/shipping worker

Type of Sampling:	personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	X 1	1 Discussion on variability and uncertainty of results

Continued on next page

Page 90 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 91 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing

adhesive formulation

vapor

Inhalation

2.3 mg/m3

1.0

8hr TWA

Bottling/shipping - Maintenance and cleaning
personal

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

This use is in scope

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium x 1 2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness High X 1 1 Discussion on variability and uncertainty of results

Continued on next page

Page 92 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 93 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Processing

adhesive formulation

vapor

Inhalation

5.9 mg/m3

1.0

short-term peak

Bottling/shipping - Maintenance and cleaning

personal

42 mins

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

This use is in scope

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium x 1 2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1 1

Discussion on variability and uncertainty of results

Continued on next page

Page 94 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 95 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	adhesive formulation

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	3.4 to 6.6 mg/m3

Number of Samples:	2.0

Type of Measurement or Method:	8hr TWA

Worker Activity:	production - stirrer cleaning

Type of Sampling:	personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	X 1	1 Discussion on variability and uncertainty of results

Continued on next page

Page 96 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 97 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Processing

adhesive formulation

vapor

Inhalation

18.7 mg/m3

1.0

short-term peak
production - stirrer cleaning
personal
19

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

This use is in scope

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium x 1 2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1 1

Discussion on variability and uncertainty of results

Continued on next page

Page 98 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 99 of 691

-------
Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EXTRACTION

Parameter	Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	adhesive formulation

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	15.5 mg/m3

Number of Samples:	1.0

Type of Measurement or Method:	8hr TWA

Worker Activity:	production - vessel cleaning

Type of Sampling:	personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	X 1	1 Discussion on variability and uncertainty of results

Continued on next page

Page 100 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 101 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Processing

adhesive formulation

vapor

Inhalation

85 mg/m3

1.0

short-term peak
production - vessel cleaning
personal
5 min

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Well described methods

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

This use is in scope

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium x 1 2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1 1

Discussion on variability and uncertainty of results

Continued on next page

Page 102 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 103 of 691

-------
Source Citation: Meier, S., Schindler, B. K., Koslitz, S., Koch, H. M., Weiss, T., Kafferlein, H. U., Briining, T.. 2013. Biomonitoring of exposure

to N-methyl-2-pyrrolidone in workers of the automobile industry. Annals of Occupational Hygiene.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3539921

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Worker Activity:

Number of Workers:

PPE:

Use

Spray application of paint in the automotive industry
liquid, vapor
dermal, inhalation

Preparing the lacquers; Loading the spraying system; After drying the
panels in an enclosed area within the spraying chamber, the panels were
finally released back into the open workspace. There, the panels were
wiped off, detached, and packed into boxes. Irregular activities included
disassembling and manually cleaning the nozzles, screws, nuts, and bolts
of the sprayers because the sprayers can get clogged. The cleaning pro-
cess included the use of pure solvent mixtures containing up to 100
per-cent NMP.

14 (10 of 14 workers were wipers/packers of dried parts and were not
regularly exposed to NMP; 2 of 14 were cleaners of spraying parts and
had the highest concentration)

Workers were required to wear thin solvent-resistant gloves made out of
laminate. The gloves were used either alone or inside a second pair of
gloves made out of polychloroprene or nitrile, which helped improve the
grip. All gloves were discarded after a single use. Workers were also able
to voluntarily use filter masks or as needed.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

trusted sources

Domain 2: Representative

Metric 2: Geographic Scope
Metric 3: Applicability

Medium x 1
High x 2

Germany
in scope

Continued on next page

Page 104 of 691

-------
— continued from previous page

Source Citation:	Meier, S.,Schindler, B. K.,Koslitz, S.,Koch, H. M.,Weiss, T.,Kafferlein, H. U.,Bruning, T.. 2013. Biomonitoring of exposure

to N-methyl-2-pyrrolidone in workers of the automobile industry. Annals of Occupational Hygiene.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3539921

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 4: Temporal Representativeness
Metric 5: Sample Size

High

N/A

x 2

2

N/A

2012

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 105 of 691

-------
Source Citation:	Xiaofei, E., Wada, Y., Nozaki, J., Miyauchi, H.,Tanaka, S., Seki, Y., Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3562767

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Use

degreasing optical lenses

vapor

Inhalation

Range = 0.09 to 0.69 ppm

20.0

1.0

full shift 12-hr TWA
all activities during a day

4

personal
12 hr/dy

5	dy/wk

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Well described methods

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Japan

Metric 3:

Applicability

High

x 2

2

Degreasing is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2000

Metric 5:

Sample Size

High

x 1

1

Statistical distribution of samples is fully characterized.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks description of all worker activities

Continued on next page

Page 106 of 691

-------
— continued from previous page

Source Citation:	Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3562767

EVALUATION





Domain Metric

Rating

MWF* Score Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

1.7



* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 107 of 691

-------
Source Citation:	Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3562767

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Use

degreasing metal parts

vapor

Inhalation

Range = 0.04 to 0.59 ppm

8.0

1.0

full shift 12-hr TWA

all activities during a day

8

personal
12 hr/dy
5 dy/wk

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Well described methods

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Japan

Metric 3:

Applicability

High

x 2

2

Degreasing is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2000

Metric 5:

Sample Size

High

x 1

1

Statistical distribution of samples is fully characterized.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks description of all worker activities

Continued on next page

Page 108 of 691

-------
— continued from previous page

Source Citation:	Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3562767

EVALUATION





Domain Metric

Rating

MWF* Score Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty.

Overall Quality Determination^

Medium

1.7



* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 109 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Worker Activity:

PPE:

Manufacturing
Manufacturing

Exposure may arise from sampling, technical maintenance and cleaning
LEV and gloves (APF 5, 80 percent )

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 110 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Number of Workers:
PPE:

Processing
formulation

Tasks include liquid transfer operations to and from bulk storage/
IBCs (intermediate bulk containers)/drums/smaller containers, mixing
in batch or continuous operations, sampling and analysis, storage and
cleaning and maintenance operations
160,000 (coating), 98,000 (cleaning)

LEV and Respiratory Protective Equipment (RPE) are employed and
protective clothing is used

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 111 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Worker Activity:

PPE:

Processing

chemical production aid

Exposure may arise from sampling, technical maintenance and cleaning
LEV and gloves (APF 5, 80 percent )

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 112 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

PPE:

Use

Coating application

Tasks include liquid transfer operations to and from bulk storage/IBCs/
drums/smaller containers, mixing in batch or continuous operations,
preparation for application, application by spraying, brushing, roller, and
dipping/immersion, film formation or within a fluidized bed system,
sampling and analysis, storage and cleaning and maintenance operations.
Protective clothing, gloves and RPE

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 113 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Number of Workers:
PPE:

Use

Cleaning

Activities arising from the use of cleaning products containing NMP
that could give rise to exposure include transfer from storage, pouring/
unloading from drums or containers, mixing/diluting prior to use, clean-
ing activities (spraying, brushing, dipping,) and associated cleaning and
maintenance of equipment.

3,400,000 (prof cleaning), 43,000 (optical cleaning), 1,080,000 (furniture
cleaning), 662,000 (paint and glaze removal?)

LEV and gloves (with training; APF20 95 percent )

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High





1.3



Continued on next page

Page 114 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 115 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

All

any stage with closed-system transfers
Inhalation

0.04 to 12.39 mg/m3
Modelled using EasyTRA
closed-system transfers. Table B65
8 hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High x 1

Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High





1.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 116 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

Manufacturing

any stage with closed-system transfers

liquid, 100 percent

dermal

0.03 to 1.37 mg/kg bw/day
Modelled using EasyTRA
closed-system transfers. Table B65
8 hr

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

Europe

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2013

Metric 5:

Sample Size

High

x 1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

High

x 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 117 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

All

any stage with manual transfers
Inhalation

3.10 to 17.35 mg/m3
Modelled using EasyTRA

Charging and discharging, including scenarios with elevated tempera-
ture. Table B66
1 to 8 hrs

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 118 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

All

any stage with manual transfers

liquid, 100 percent

dermal

0.34 to 2.74 mg/kg bw/day
Modelled using EasyTRA

Charging and discharging, including scenarios with elevated tempera-
ture. Table B66
1 to 8 hrs

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 119 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

Processing

formulation

Inhalation

0.04 to 20.65 mg/m3
Modelled using EasyTRA
mixing and blending
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 120 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

Processing
formulation
liquid, 100 percent
dermal

0.69 to 2.74 mg/kg bw/day
Modelled using EasyTRA
mixing and blending
8 hr

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

Europe

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2013

Metric 5:

Sample Size

High

x 1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

High

x 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 121 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	adhesive formulation

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	same data as source 3539720

Type of Measurement or Method:	Measured

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

This use is in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks certain metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 122 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

spray application of substrate (coating, cleaner, etc.)
Inhalation

7.96 to 18.70 mg/m3

Modelled using Stoffenmanager and RISKOFDERM
4 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 123 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

spray application of substrate (coating, cleaner, etc.)
dermal

1.73 to 3.46 mg/kg bw/day

Modelled using Stoffenmanager and RISKOFDERM
4 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 124 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

roll /brush application of substrate (coating, cleaner, etc.

Inhalation

4.13 mg/m3

Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 125 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

roll /brush application of substrate (coating, cleaner, etc.
dermal

5.49 mg/kg bw/day
Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 126 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

dip application of substrate (coating, cleaner, etc.
Inhalation

4.13 to 12.40 mg/m3
Modelled using EasyTRA
4 to 8 hr/day

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 127 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

dip application of substrate (coating, cleaner, etc.
dermal

1.64 to 2.74 mg/kg bw/day
Modelled using EasyTRA
4 to 8 hr/day

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 128 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

screen printing plant

Inhalation

7.1 to 22.2 mg/m"

unknown

1.0

unknown
unknown
unknown
unknown

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4

Geographic Scope
Applicability

Temporal Representativeness

Metric 5: Sample Size

Low
High

Unacceptable
Low

x 1
x 2
x 2

x 1

3 unknown

2	in scope

8	1988 - so different as to make outdated information unaccept-

able

3	characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

Unacceptable

4

Metric Mean Score: 2.1.

Continued on next page

Page 129 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

** Consistent with our Application of Systematic Review in TSCA Risk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),

EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 130 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Analytic Method:

Use

paint stripping
Inhalation
up to 64 mg/m3
unknown
8-hr TWA
unknown
personal?

8 hr

note: in paint stripper RA

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	Low	x 1	3

Applicability	High	x 2	2

Temporal Representativeness	Medium	x 2	4

Sample Size	Medium	x 1	2

unknown
in scope
2000

some statistics unknown

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 131 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 132 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Analytic Method:

Use

paint stripping
Inhalation
280 mg/m3
unknown
1-hr peak
unknown
personal?

1 hr

note: in paint stripper RA

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	Low	x 1	3

Applicability	High	x 2	2

Temporal Representativeness	Medium	x 2	4

Sample Size	Medium	x 1	2

unknown
in scope
2000

some statistics unknown

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 133 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 134 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Analytic Method:

Use

graffiti removal
Inhalation
10 mg/m3
unknown
8-hr TWA
unknown
personal
8 hr

note: in paint stripper RA

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	Low	x 1	3

Applicability	High	x 2	2

Temporal Representativeness	Medium	x 2	4

Sample Size	Medium	x 1	2

unknown

in scope with paint stripping?

2000

some statistics unknown

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 135 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 136 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Use

paint stripping

Inhalation

0.82 to 4.1 mg/m3

unknown

unknown

Worker Activity:



unknown







Type of Sampling:



unknown







Exposure Duration:



unknown







Analytic Method:



note: in paint stripper RA



EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

unknown

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2004

Metric 5:

Sample Size

Low

x 1

3

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

Medium

1.7

Continued on next page

Page 137 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 138 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

all

tank cleaning

Inhalation

4.1 to 12.4 mg/m3

unknown

unknown

unknown

unknown

unknown

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High
Low

X 1

x 2
x 2
x 1

3
2

2

3

unknown
in scope
2011

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.4



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 139 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	cleaning of instruments

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	same data as 735269

Type of Measurement or Method:	Measured

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Information from trusted sources

Domain 2: Representative

Metric 2: Geographic Scope

Medium

X

1

2

Japan

Metric 3: Applicability

High

X

2

2

in scope

Metric 4: Temporal Representativeness

High

X

2

2

2009

Metric 5: Sample Size

Medium

X

1

2

some statistics unknown

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^	High	1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 140 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Processing

polymer

Inhalation

air concentrations exceeding the DNEL of 5 mg/m3 by approximately

5-fold

unknown

Measured

during preparation and initiating of the production pr

both

unknown

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	Low	x 1	3

Applicability	High	x 2	2

Temporal Representativeness	Medium x 2	4

Sample Size	Low	x 1	3

unknown
in scope
2005

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

Medium

1.7

Continued on next page

Page 141 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 142 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use
lab

Inhalation
2.07 - 4.13 mg/m3
Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 143 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use
lab

dermal

0.34 mg/kg bw/day
Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 144 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

lubrication and grease application

Inhalation

8.26 - 15.49 mg/m3

Modelled using EasyTRA

8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 145 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

lubrication and grease application
dermal

2.74 to 5.49 mg/kg bw/day
Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 146 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

Spray application of agrichemicals

Inhalation

2.97 to 5.27 mg/m3

Modelled using EasyTRA

8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 147 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Exposure Duration:

Use

Spray application of agrichemicals
dermal

2.21 to 5.38 mg/kg bw/day
Modelled using EasyTRA
8 hr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 148 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

All
All

dermal

Input parameters are defaults as given in ECHA guidance (chapter R14
Occupational exposure estimation).

Modelled using EasyTRA

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

High

X

1

1

Multiple data points provided with necessary metadata

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty of results

Overall Quality Determination^

High

1.2

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 149 of 691

-------
Source Citation: Who,. 2001. Concise International Chemical Assessment Document 35: N-Methyl-2-Pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3809476

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Type of Sampling:

Analytic Method:

Use

graffiti removal
vapor
Inhalation
up to 10 mg/m3
8-hr TWA
personal

note: in paint stripper RA

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

unknown

Metric 3:

Applicability

High

in scope with paint stripping?

Metric 4:

Temporal Representativeness

Low

1993-2000

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Monitoring data include sample type (e.g., personal breathing

zone) but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion

Overall Quality Determination^

Low

2.4

* MWF = Metric Weighting Factor

Page 150 of 691

-------
Source Citation:	Who,. 2001. Concise International Chemical Assessment Document 35: N-Methyl-2-Pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3809476

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	microelectronic industry

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	up to 6 mg/m3

Type of Measurement or Method:	8-hr TWA

Type of Sampling:	personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

unknown

Metric 3:

Applicability

Medium

x 2

4

Not fully specified; could be cleaning in electronics industry

Metric 4:

Temporal Representativeness

Low

x 2

6

1991

Metric 5:

Sample Size

Low

x 1

3

characterized by no statistics.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks worker activities

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^	Low	2.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 151 of 691

-------
Source Citation:	Who,. 2001. Concise International Chemical Assessment Document 35: N-Methyl-2-Pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3809476

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Type of Sampling:

Use

microelectronic industry

vapor

Inhalation

up to 280 mg/m3 (temperature of 80" C)

full-shift

area

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

unknown

Metric 3:

Applicability

Medium

x 2

4

Not fully specified; could be cleaning in electronics industry

Metric 4:

Temporal Representativeness

Low

x 2

6

1991

Metric 5:

Sample Size

Low

x 1

3

characterized by no statistics.

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Lacks worker activities

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^	Low	2.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 152 of 691

-------
Source Citation:	Who,. 2001. Concise International Chemical Assessment Document 35: N-Methyl-2-Pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3809476

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	paint stripping

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	up to 64 mg/m3

Type of Measurement or Method:	8-hr TWA

Type of Sampling:	personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

unknown

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2000

Metric 5:

Sample Size

Low

X

1

3

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks worker activities

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 no discussion

Overall Quality Determination^

Medium

2.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 153 of 691

-------
Source Citation:	Who,. 2001. Concise International Chemical Assessment Document 35: N-Methyl-2-Pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3809476

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	paint stripping

Physical Form:	vapor

Route of Exposure:	Inhalation

Exposure Concentration (Unit):	280 mg/m3

Type of Measurement or Method:	1-hr peak

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

unknown

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2000

Metric 5:

Sample Size

Low

X

1

3

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 Lacks worker activities

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 no discussion

Overall Quality Determination^

Medium

2.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 154 of 691

-------
Source Citation: U.S, E. P. A.. 1998. Environmental profile for N-methylpyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827493

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Worker Activity:

Type of Sampling:

Use

photoresist remover

vapor

Inhalation

typical: 0.02 to 1.5 ppm

Industrial hygiene evaluations were performed in the die-coat application
areas, in the NMP cleaning rooms, and in rooftop stack exhausts,
area

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

Sampling or analytical methodology is not specified

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
Low
Low

X 1

x 2
x 2
x 1

2
6

unknown
in scope
1991

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

Lacks sample duration, exposure duration, frequency, and
worker activities

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

does not address variability or uncertainty.

Overall Quality Determination^

Low

2.4

* MWF = Metric Weighting Factor

Page 155 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Exposure Duration:

Exposure Frequency:

PPE:

Use

paint stripping

liquid

dermal

PBPK modelling

skin surface contact = 445 (low-end), 668 (mid), and 890 (high-end)
cm2; body weight = 74 kg

Total <230,000 workers. There were no risks to nearby worker non-users.
Assumed durations of 1-hr, 4-hrs, and 8-hrs

Acute scenarios assumed 1 day of exposure and chronic scenarios as-
sumed 5 days of exposure per week

EPA considered the impact of different combinations of PPE including:
respirator and gloves, respirator only, gloves only, and neither respirator
nor gloves.

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Data and techniques are high quality; Information from trusted

sources.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2015

Metric 5:

Sample Size

High

X

1

1

Statistical distribution of samples is fully characterized. Sam

pie size is sufficiently representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High x 1	1 clearly documents its data sources

Continued on next page

Page 156 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High x 1	1 well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 157 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Exposure Duration:
Exposure Frequency:

PPE:

Use

paint stripping

liquid

Inhalation

1.0 (low-end), 32.5 (mid), 64 (high-end) mg/m3
8-hr TWA

Miscellaneous stripping (assumed mostly indoor)

Total <230,000 workers. Professional contractors (likely to include bath-
tub refinishing): 5 workers/facility; Automotive refinishing: 6 workers/
facility; Furniture refinishing: 3 workers/facility; Art restoration and
conservation (not estimated); Aircraft paint stripping: 320 workers/
facility (for aircraft manufacturing only); Ship paint stripping: 100 work-
ers/facility. There were no risks to nearby worker non-users.

Assumed durations of 1-hr, 4-hrs, and 8-hrs

Acute scenarios assumed 1 day of exposure and chronic scenarios as-
sumed 5 days of exposure per week

EPA considered the impact of different combinations of PPE including:
respirator and gloves, respirator only, gloves only, and neither respirator
nor gloves.

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Data and techniques are high quality; Information from trusted











sources.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2015

Continued on next page

Page 158 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Occupational Exposure; Completed Exposure or Risk Assessments;

3827504

EVALUATION

Domain

Metric

Rating

MWF* Score

Comments



Metric 5; Sample Size

High

X 1 1

Statistical distribution of samples is fully characterized. Sam-
ple size is sufficiently representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1 1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1 1

well characterized

Overall Quality Determination^

High

1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 159 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Exposure Duration:

Exposure Frequency:

PPE:

Use

graffiti removal

liquid

Inhalation

0.03 (low-end), 1.01 (mid), 4.52 (high-end) mg/m3
8-hr TWA

Graffiti removal (assumed mostly outdoor but may include semi-confined
spaces)

Total <230,000 workers. 8 workers/facility. There were no risks to

nearby worker non-users.

Assumed durations of 1-hr, 4-hrs, and 8-hrs

Acute scenarios assumed 1 day of exposure and chronic scenarios as-
sumed 5 days of exposure per week

EPA considered the impact of different combinations of PPE including:
respirator and gloves, respirator only, gloves only, and neither respirator
nor gloves.

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Data and techniques are high quality; Information from trusted

sources.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope with paint stripping?

Metric 4:

Temporal Representativeness

High

X

2

2

2015

Metric 5:

Sample Size

High

X

1

1

Statistical distribution of samples is fully characterized. Sam

pie size is sufficiently representative.

Continued on next page

Page 160 of 691

-------
— continued from previous page

Source Citation: U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID 3827504

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 3; Accessibility/Clarity

Metric 6; Metadata Completeness

High

X 1 1 clearly documents its data sources

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

High

X 1 1 well characterized

Overall Quality Determination^

High

1.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 161 of 691

-------
Source Citation: U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID 3827504

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

paint stripping

liquid

Inhalation

0.01 to 280 mg/m3

measured - see Table Apx D-9

during stripping - see Table Apx D-9

personal

43 to 167 mins

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Data and techniques are high quality; Information from trusted

sources.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2015

Metric 5:

Sample Size

High

x 1

Statistical distribution of samples is fully characterized. Sam-

pie size is sufficiently representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High X 1 1 clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High X 1 1 well characterized

Overall Quality Determination^

High 1.0

Continued on next page

Page 162 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 163 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

paint stripping
liquid
Inhalation
64 mg/m3
8-hr TWA

during stripping - see Table Apx D-9
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Data and techniques are high quality; Information from trusted











sources.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2015

Metric 5:

Sample Size

High

x 1

1

Statistical distribution of samples is fully characterized. Sam-

pie size is sufficiently representative.

Domain 3: Accessibility/Clarity



Metric 6: Metadata Completeness

High X 1 1 clearly documents its data sources

Domain 4: Variability and Uncertainty



Metric 7: Metadata Completeness

High X 1 1 well characterized

Overall Quality Determination^

High 1.0

Continued on next page

Page 164 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 165 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

graffiti removal

liquid

Inhalation

0.56 to 1.78 mg/m3

8-hr TWA

during graffiti removal - see Table Apx D-9
personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Data and techniques are high quality; Information from trusted

sources.

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	High	x 1	1

Applicability	High	x 2	2

Temporal Representativeness	High	x 2	2

Sample Size	High	x 1	1

US

in scope with paint stripping?

2015

Statistical distribution of samples is fully characterized,
pie size is sufficiently representative.

Domain 3: Accessibility/Clarity



Metric 6: Metadata Completeness

High X 1 1 clearly documents its data sources

Domain 4: Variability and Uncertainty



Metric 7: Metadata Completeness

High X 1 1 well characterized

Overall Quality Determination^

High 1.0

Continued on next page

Page 166 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 167 of 691

-------
Source Citation: U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID 3827504

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

graffiti removal

vapor

Inhalation

Range: 0.01 to 24.61Geometric mean: 1.97Mean: 4.71Standard devia-
tion: 6.17

15-min short term sample

during graffiti removal - see Table Apx D-9

personal

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Data and techniques are high quality; Information from trusted

sources.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

in scope with paint stripping?

Metric 4:

Temporal Representativeness

High

2015

Metric 5:

Sample Size

High

Statistical distribution of samples is fully characterized. Sam

pie size is sufficiently representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness High x 1 1 well characterized

Overall Quality Determination^ High 1.0

Continued on next page

Page 168 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	3827504

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 169 of 691

-------
Source Citation:

2017. PubChem: l-Methyl-2-pyrrolidinone.

Type of Data Source

Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3860487

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	All

Number of Workers:	85169 workers estimated to be exposed to NMP in US at workplaces

where NMP is produced or used

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

From NIOSH

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
Medium
Low
N/A

X 1

x 2
x 2

1

4
6

N/A

US

Not fully specified; could include out of scope stages
1983

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

No metadata, but still can be applied

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^

Medium



2.1



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 170 of 691

-------
Source Citation:

2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source

Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3860493

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	All

Worker Activity:	all workers potentially exposed

Number of Workers:	85,169 workers

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

From NIOSH

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
Medium
Low
N/A

X 1

x 2
x 2

1

4
6

N/A

US

Not fully specified; could include out of scope stages
1983

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

No metadata, but still can be applied

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^

Medium



2.1



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 171 of 691

-------
Source Citation:

2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

3860493

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Wood preservative

Exposure Concentration (Unit):	142 ug/m3

Type of Sampling:	area

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
Low
Low

X 1

x 2
x 2
x 1

3

2
6

3

unknown
in scope
1997

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Monitoring data include sample type (e.g., personal breathing
zone) but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

Low



2.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 172 of 691

-------
Source Citation: Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID 3969286

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Type of Measurement or Method:

Consumer Use
Coatings
liquid
dermal

Floor lacquer A = 108 cm2Writing A = 1 cm2

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology

Low

x 1

3 the model makes assumptions or uses parameter values that

lead to significant uncertainties

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Low x 2

Metric 4: Temporal Representativeness
Metric 5: Sample Size

High

N/A

x 2

2 Australia

6 non-occupational scenario that is similar to an occupational

scenario
2 2016
N/A No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 Model approach, equations, and choice of parameter values are

transparent. However, rationale not fully described.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 well characterized

Overall Quality Determination^

Medium

2.0

* MWF = Metric Weighting Factor

Page 173 of 691

-------
Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3969286

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Type of Measurement or Method:

Consumer Use
Cleaning
liquid
dermal

Spot removal = 230 cm2Paint remover = 430 cm2Sealant /foam remover
A = 5 cm2

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X

1

3

the model makes assumptions or uses parameter values that
lead to significant uncertainties

Domain 2: Representative













Metric 2:

Geographic Scope

Medium

X

1

2

Australia

Metric 3:

Applicability

Low

X

2

6

non-occupational scenario that is similar to an occupational













scenario

Metric 4:

Temporal Representativeness

High

X

2

2

2016

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Model approach, equations, and choice of parameter values are

transparent. However, rationale not fully described.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 well characterized

Overall Quality Determination^

Medium

2.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 174 of 691

-------
Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3969286

EXTRACTION
Parameter

Data







Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Consumer Use

Ink

vapor

Inhalation

Assumed negligible due to small volume of use

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Low

X 1

3

the model makes assumptions or uses parameter values that
lead to significant uncertainties

Domain 2: Representative

Metric 2: Geographic Scope
Metric 3: Applicability

Metric 4: Temporal Representativeness
Metric 5: Sample Size

Medium
Low

High

N/A

X 1

x 2
x 2

2
6

2

N/A

Australia

non-occupational scenario that is similar to an occupational
scenario

2016

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Model approach, equations, and choice of parameter values are
transparent. However, rationale not fully described.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

Medium



2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 175 of 691

-------
Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3969286

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Consumer Use
Coating and cleaning
vapor
Inhalation

mean concentration ranged 54.3 to 217 mg/m3 for products containing
50 and 25 percent of NMP; 10.4 to 113 mg/m3 for 5 percent NMP; and
0.623 to 12.9 for mg/m3 for 0.3 percent NMP

Modeled based on saturation and parameters in Table 5 (ventilation,
time)

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Low

x 1

the model makes assumptions or uses parameter values that
lead to significant uncertainties

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Low	x 2

Metric 4: Temporal Representativeness High
Metric 5: Sample Size	N/A

x 2

2
6

2

N/A

Australia

non-occupational scenario that is similar to an occupational
scenario

2016

No Comment.

Domain 3: Accessibility/Clarity

Metric 6; Metadata Completeness	Medium X 1	2 Model approach, equations, and choice of parameter values are

transparent. However, rationale not fully described.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	x 1	1 well characterized

Continued on next page

Page 176 of 691

-------
— continued from previous page

Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3969286

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 177 of 691

-------
Source Citation: Niosh,. 2014. Health hazard evaluation report no. HHE-2011-0099-3211, evaluation of employee exposures during sea lamprey

pesticide application.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3974909

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Number of Workers:

Exposure Frequency:

PPE:

Use

Agricultural products

Mixing pesticides with water prior to application; application; lab anal-
yses to measure concentration upon application
38 employees

10-day periods throughout the season (April to October)

Eye protection (safety glasses, goggles, or face shield) and chemical resis-
tant gloves when mixing and applying pesticide. NIOSH-approved full
facepiece dual cartridge (particulate and organic vapor) respirator when
using the Bayluscide wettable powder and Bayluscide granular.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Information is from trusted sources (NIOSH HHE)

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

Agricultural use is in scope

Metric 4:

Temporal Representativeness

High

x 2

2014

Metric 5:

Sample Size

High

x 1

Sample size is sufficiently representative. Results are from in-

terviewing of 20 employees.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1 1

The report addresses variability and uncertainty in the results.

Continued on next page

Page 178 of 691

-------
— continued from previous page

Source Citation:	Niosh,. 2014. Health hazard evaluation report no. HHE-2011-0099-3211, evaluation of employee exposures during sea lamprey

pesticide application.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3974909

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 179 of 691

-------
Source Citation: Osha,. 2010. Input received through web forum for identifying hazardous chemicals for which OSHA should develop exposure

reduction strategies.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3978176

EXTRACTION

Parameter Data

Life Cycle Stage: All

Life Cycle Description (Subcategory of Use): Source was listed for exposure data, but only contained exposure limits.

No data extracted

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

OSHA

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High

Unacceptable

High

N/A

X 1

x 2
x 2

N/A

No information relevant to assessed conditions of use
2010

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.0.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 180 of 691

-------
Source Citation:

Osha,. 2017. Sampling and analytical methods: N-methyl-2-pyrrolidinone.

Type of Data Source

Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3978312

EXTRACTION

Parameter

Data

Life Cycle Stage: All

Life Cycle Description (Subcategory of Use): Source was listed for exposure data, but only contained exposure limits.

No data extracted

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

OSHA

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High

Unacceptable

High

N/A

X
X
X

2
2

N/A

No information relevant to assessed conditions of use
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

Unacceptable

Metric Mean Score: 1.9.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 181 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Worker Activity:

Number of Workers:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:
PPE:

Formulation

polymeric adhesive for leather coating application

liquid, 5 percent

dermal

Transferring and adding primal Binder U-51 and other components into

the mixing vessel.

2-3 /site

4-6 hours/day

100 days/year

Exhaust ventilation systems are installed in the mixing room.

Safety glasses, impervious gloves. Overalls and safety boots

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information is from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Australia

Metric 3:

Applicability

High

x 2

2

Adhesive formulation is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2001

Metric 5:

Sample Size

Low

x 1

3

Distribution of samples is qualitative

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Assessment or report clearly documents its data sources, as-











sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

limited discussion

Continued on next page

Page 182 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978357

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 183 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Worker Activity:

Number of Workers:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Use

spray application of polymeric adhesive for leather coating application
liquid, 5 percent
dermal, inhalation

Transferring basecoat and operating spray machines. Placing substrates

on conveyor line.

2-3 /site

6-8 hours/day

100 days/year

Enclosed rotary spray unit. An exhaust ventilation system is present
above the spray machines and any overspray is filtered and caught in a
water curtain filtering system.

Safety glasses, impervious gloves. Overalls and safety boots

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information is from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Australia

Metric 3:

Applicability

High

x 2

2

Adhesive use is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2001

Metric 5:

Sample Size

Low

x 1

3

Distribution of samples is qualitative

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Assessment or report clearly documents its data sources, as-











sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Continued on next page

Page 184 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978357

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Metric 7: Metadata Completeness

Medium

X 1 2 limited discussion



Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 185 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Worker Activity:

Number of Workers:

Processing

Distribution polymeric adhesive for leather coating application

liquid, 5 percent

dermal

Load/unload drums from trucks. No exposure anticipated except in the
event of an accident.

5 Waterside, workers, 5-10 transport and warehouse workers

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Information is from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	X 1	2	Australia

High	X 2	2	Distribution is in scope

Medium	x 2	4	2001

Low	X 1	3	Distribution of samples is qualitative

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion

Overall Quality Determination^

Medium

1.7



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 186 of 691

-------
Source Citation:

Basf,. 1990. Technical information: N-methylpyrrolidone handling and storage.

Type of Data Source

Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3982070

EXTRACTION

Parameter

Data

Life Cycle Stage: All

Life Cycle Description (Subcategory of Use): recommended PPE

PPE: Chemical splash goggles should be worn. Gloves of butyl rubber and

FEP Teflon provide the best resistance to NMP. Gloves should be rinsed
following use and discarded. Butyl rubber aprons may be used for splash
protection, however, the PVC coatings' found on much protective cloth-
ing rapidly dissolve in NMP.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

Medium

Information is not related to a life cycle stage, but is broadly

applicable

Metric 4:

Temporal Representativeness

Low

1990

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Low

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ Low 2.3

* MWF = Metric Weighting Factor

Page 187 of 691

-------
Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982074

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Use

immersion degreasing

vapor

Inhalation

average = 0.31 ppm

Worker Activity:
Type of Sampling:



collection tube was located 5.0 feet away from the front lip of the de-
greaser top (exhaust hood was located at back lip of degreaser top) and
3.0 feet off of the floor
area

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

The data, data sources, and/or techniques used in the assess-
ment or report are not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
Low

X 1

x 2
x 2
x 1

1

2
6

3

US

Cleaning is included in scope
1993

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

provides results, but the underlying methods, data sources,
and assumptions are not fully transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

The report does not address variability or uncertainty.

Overall Quality Determination^

Low



2.3



Continued on next page

Page 188 of 691

-------
— continued from previous page

Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982074

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 189 of 691

-------
Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982074

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Worker Activity:

Type of Sampling:

Use

immersion degreasing

vapor

Inhalation

average =1.84 ppm

Collection tube was taped into place on the workers shirt
personal

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

Low

X 1 3 The data, data sources, and/or techniques used in the assess-







ment or report are not specified.

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

Cleaning is included in scope

Metric 4: Temporal Representativeness

Low

X

2

6

1993

Metric 5: Sample Size

Low

X

1

3

characterized by no statistics.

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

Low

X

1

3

provides results, but the underlying methods, data sources,











and assumptions are not fully transparent

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

Low

X

1

3

The report does not address variability or uncertainty.

Overall Quality Determination^

Low





2.3



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 190 of 691

-------
Source Citation:	Oehha,. 2007. Occupational health hazard risk assessment project for California: Identification of chemicals of concern,

possible risk assessment methods, and examples of health protective occupational air concentrations.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3982225

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

Exposure Frequency:

All
All

vapor
Inhalation
0.4 to 5 ppm

modelled using interspecies uncertainty factors

Workers were assumed to breathe 10 m3 out of a daily breathing rate of
20 m3/day, and be exposed at the PEL for 5 days per week.

8 hrs

5 days/wk

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium x 1	2 Seems sound, but utilizes animal studies to derive human val-

ues

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

can be appropriately applied

Metric 4:

Temporal Representativeness

Medium

X

2

4

2007

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High

X 1	1	Model approach, equations, and choice of parameter values are

transparent and clear and can be evaluated. Rationale for se-
lection of approach, equations, and parameter values is pro-
vided.

Domain 4: Variability and Uncertainty

Continued on next page

Page 191 of 691

-------
— continued from previous page

Source Citation:	Oehha,. 2007. Occupational health hazard risk assessment project for California: Identification of chemicals of concern,

possible risk assessment methods, and examples of health protective occupational air concentrations.

Type of Data Source Occupational Exposure; Published Models for Exposures or Releases;

Hero ID	3982225

EVALUATION





Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

High

X 1 1 The model characterizes variability and uncertainty in the re-
sults.

Overall Quality Determination^

High

1.4



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 192 of 691

-------
Source Citation: Hesis,. 2014. N-methylpyrrolidone (nmp): Health hazard advisory: Fact sheet.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3982238

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Type of Measurement or Method:

PPE:

Use
all

This document lists health effects and suggested PPE.

Half-face respirator with organic vapor cartridges. In spraying opera-
tions, this should be combined with a mist pre-filter. Wear chemical
protective utility gloves such as butyl rubber or Silvershield" (laminated
polyethylene/EVOH). NMP will go right through less durable gloves
such as those made of natural rubber, nitrile, or polyethylene. Replace
gloves often. Use chemical protective clothing such as aprons, sleeves,
boots, and head and face protection if NMP can contact your skin at
areas other than your hands.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High x 1 1 CalOSHA

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

PPE suggestions applicable to in-scope uses

Metric 4:

Temporal Representativeness

High

2014

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Medium x 1 2 limited discussion

Continued on next page

Page 193 of 691

-------
— continued from previous page

Source Citation:	Hesis,. 2014. N-methylpyrrolidone (nmp): Health haazard advisory: Fact sheet.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982238

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	High	1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 194 of 691

-------
Source Citation: Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3982353

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): graffiti removal

Physical Form: vapor

Route of Exposure: Inhalation

Exposure Concentration (Unit): up to 10 mg/m3

Type of Sampling: personal

Analytic Method: note: in paint stripper RA

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Low X 1 3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

unknown

Metric 3:

Applicability

High

in scope with paint stripping?

Metric 4:

Temporal Representativeness

Low

1993-2000

Metric 5:

Sample Size

Low

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Monitoring data include sample type (e.g., personal breathing

zone) but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion

Overall Quality Determination^

Low

2.4

* MWF = Metric Weighting Factor

Page 195 of 691

-------
Source Citation:	Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982353

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Sampling:

Use

microelectronic industry

vapor

Inhalation

up to 6 mg/m3 (reg temp); up to 280 mg/m3 (temperature of 80"C)
personal

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
Medium
Low
Low

X 1

x 2
x 2
x 1

3

4
6
3

unknown

Not fully specified; could be cleaning in electronics industry
1991

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Monitoring data include sample type (e.g., personal breathing
zone) but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^	Low	2.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 196 of 691

-------
Source Citation:	Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982353

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Sampling:

Analytic Method:

Use

paint stripping

vapor

Inhalation

up to 64 mg/m3; peak 280 mg/m3
personal

note: in paint stripper RA

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

unknown

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2000

Metric 5:

Sample Size

Low

X

1

3

characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but no other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion

Overall Quality Determination^

Medium

2.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 197 of 691

-------
Source Citation:	Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982353

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

All
All

vapor
dermal

30 percent of the total inhalation dose
experimental study in human volunteers

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
Medium
Medium
Low

X 1

x 2
x 2
x 1

3

4
4
3

unknown

Not fully specified; could be applied to in scope
2007

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

No metadata, but still can be applied

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^	Low	2.4

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 198 of 691

-------
Source Citation:	Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982353

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

All
All

dermal

15 minutes exposure to 15 percent aqueous NMP is equivalent to
inhalation of 10 mg/m3 NMP with respect to absorption

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
Medium
Medium
Low

X 1

x 2
x 2
x 1

3

4
4
3

unknown

Not fully specified; could be applied to in scope
2002

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

No metadata, but still can be applied

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^	Low	2.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 199 of 691

-------
Source Citation:	Ec,. 2007. Recommendation from the scientific committee on occupational exposure limits for n-methyl-2-pyrrolidone.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3982353

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

All
All

dermal

permeability rate through human skin of 171 + 59 g/m3 has been derived
for NMP

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
Medium
Low
Low

X 1

x 2
x 2
x 1

3

4
6
3

unknown

Not fully specified; could be applied to in scope
1995

characterized by no statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

No metadata, but still can be applied

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^	Low	2.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 200 of 691

-------
Source Citation: U.S, E. P. A.. 2013. OPPT N-Methylpyrrolidone (NMP) draft risk assessment final comments of nine member peer review

panel December 31, 2013.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986611

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Type of Measurement or Method:

Use

paint stripping

This source is a review of EPA's Draft Paint Stripping RA. It lists mod-
elling considerations.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2013

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium x 1

2 Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 limited discussion of the variability and uncertainty in the re-
sults

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 201 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Thomas, T. 2017. Comment submitted by Todd Thomas, ELANTAS PDG, Inc. (EPDG).
Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
3986789

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Number of Workers:

Engineering Control & percent Exposure Reduction:

Processing /Use

Polymers and Electronics (wires)

5 to 10

NMP is used in the following process conditions: Enclosed process vessels
with emissions sent to an RTO; includes manufacturing and cleaning op-
erations; Small enclosed process vessel (<30 gallons); emissions are fugi-
tive; Filling operations into drums, IBC's and tank wagons; emissions
are fugitive; Bulk and container storage operations; Regulated metal
parts washers; emissions are fugitive

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

Continued on next page

Page 202 of 691

-------
— continued from previous page

Source Citation:	Thomas, T. 2017. Comment submitted by Todd Thomas, ELANTAS PDG, Inc. (EPDG).

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986789

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 203 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): electronics - Photoresist Stripping

Engineering Control & percent Exposure Reduction: Closed conveyorized equipment or tank with exhaust ventilation; Venti-

lation within the process enclosures are used to maintain proper work-
place exposure levels.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X
X
X

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^ High 1.1

* MWF = Metric Weighting Factor

Page 204 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:
PPE:

Use

electronics - Soldermask Stripping

open topped tankequipped with ventilation

Worker exposure is controlled via ventilation and use of appropriate PPE.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 205 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:
PPE:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
closed reaction system; local ventilation
personnel are equipped with PPE

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 206 of 691

-------
Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:
PPE:

Use

Fertilizer application

closed system tank mixer in a continuous process
PPE, respirators

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 207 of 691

-------
Source Citation: Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3986801

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics - semiconductor manufacturing

The wafer fabrication activities listed in this table would normally be
conducted within robotically operated enclosed tools, where engineering
controls (chamber containment) provide exposure control during normal
operations. List of specific controls on page 10.

Unspecified PPE

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

Trade association poll of manufacturers. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 208 of 691

-------
Source Citation: National Electrical Manufacturers Association. 2017. Comment submitted by National Electrical Manufacturers Association

(NEMA).

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986803

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics - magnet wires

the polymer applicator and curing oven are completely enclosed; process

is completely enclosed and ventilated.

gloves, aprons and goggles as well as engineering controls

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 209 of 691

-------
Source Citation:	E. I. Dupont De Nemours, Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA

SUBMIT-TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH
ATTACHMENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Worker Activity:

Type of Sampling:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

0.005 ppm (mean) 0.2 ppm (max)

21.0

1.0

Organic polymer prep and solvent recovery
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1989

Metric 5:

Sample Size

Medium

x 1

2

Characterized by a range

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Monitoring data lacks sample durations and/or measurement











method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 210 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.1

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 211 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Worker Activity:

Type of Sampling:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

0.2 ppm, 1 ppm

2.0

1.0

Manufacture of composite prepreg
personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 212 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 213 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Worker Activity:

Type of Sampling:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

6 ppm, 1 ppm

2.0

1.0

Resin heating mill hood
area

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 214 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 215 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Worker Activity:

Type of Sampling:

Sampling Location:

Use

Paints and Coatings application

Vapor

Inhalation

0.13 ppm (mean)0.2 (max)

3.0

1.0

Equipment clean up in paint shop

personal

paint shop

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

Use in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1989

Metric 5:

Sample Size

Medium

x 1

2

Characterized by a range

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 216 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 2.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 217 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Worker Activity:

Type of Sampling:

Exposure Frequency:

PPE:

Use

Paints and Coatings application

Vapor

Inhalation

2.0 ppm (mean)3.0 ppm (max)

2.0

1.0

Solvent for spray application of roll coating

personal

25 min

Respiratory and skin protection worn

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

Use in scope

Metric 4:

Temporal Representativeness

Low

x 2

6

1989

Metric 5:

Sample Size

Medium

x 1

2

Characterized by a range

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Monitoring data lacks sample durations and/or measurement











method

Domain 4: Variability and Uncertainty

Continued on next page

Page 218 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

Low

X 1 3 No discussion on uncertainty and variability

Overall Quality Determination^

Medium

2.1



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 219 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Curing composite article at 800 F
personal

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 220 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 221 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Curing composite article at 800 F
area

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 222 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 223 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Devolatilizing composite article in laboratory hood
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
High

X 1

x 2
x 2
x 1

1

2
6
1

US

Processing in scope
1989

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Monitoring data lacks sample durations and/or measurement
method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

No discussion on uncertainty and variability

Overall Quality Determination^

Medium



2.0



Continued on next page

Page 224 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 225 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Devolatilizing composite article in ventilated press
personal

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 226 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 227 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Devolatilizing composite article in ventilated press
area

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 228 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 229 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Impregnating fibers with resin in laboratory hood
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
High

X 1

x 2
x 2
x 1

1

2
6
1

US

Processing in scope
1989

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Monitoring data lacks sample durations and/or measurement
method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

No discussion on uncertainty and variability

Overall Quality Determination^

Medium



2.0



Continued on next page

Page 230 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 231 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

2.0

Cut patterns from prepreg and devolatilized for 2 hours
personal

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 232 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 233 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Cut patterns from prepreg and devolatilized for 2 hours
area

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 234 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 235 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

<0.1 ppm

1.0

Operator cut patterns from prepreg
personal

skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 236 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 237 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

Exposure Frequency:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

5.2 ppm

1.0

Clean up of 310 F heater plates
personal
9 min

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 238 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 239 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

Exposure Frequency:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

3.7 ppm, 10 ppm

2.0

Clean up of 310 F heater plates

personal

13 min

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 240 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 241 of 691

-------
Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Worker Activity:

Type of Sampling:

Exposure Frequency:

PPE:

Processing

Processing Non-Incorporative (polymer manufacturing)

Vapor

Inhalation

12 ppm

1.0

Clean up of 310 F heater plates

personal

17 min

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Low	X 1	3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Processing in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

High

X

1

1

Discrete data point provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data lacks sample durations and/or measurement

method

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 242 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4214100

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 243 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Manufacturing
Manufacturing
Vapor
Inhalation

5	mg/day, avg breathing rate of 1.25 m3/hr
3.0

CEB drumming model
sampling and packaging

6	to 10 per site

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 244 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 245 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Manufacturing
Manufacturing
liquid

Dermal contact
1300 - 3900 mg/day
3.0

CEB two hand immersion model
sampling and packaging
6 to 10 per site

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 246 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 247 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Processing

Processing Non-Incorporative (lube oil extraction)

vapor

Inhalation

>0.1 mg/day

CEB sampling model

Lube oil extraction

5999 - 17000

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Overall Quality Determination^	Medium	1.8

Continued on next page

Page 248 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 249 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Processing

Processing Non-Incorporative (lube oil extraction)
liquid

Dermal contact

1300 - 3900 mg/day

CEB two hand immersion model

Lube oil extraction

6000 - 17000

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Overall Quality Determination^	Medium	1.8

Continued on next page

Page 250 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 251 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Use

Paint and coating removers

Vapor

Inhalation

up to 16 mg/day

Manipulating current methylene chloride data by vapor pressures
Stripper applied to surface by spraying or brushing or dipping. Time
given to penetrate. Stripper removed, wiped or scraped.

2,500-10,700

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 252 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 253 of 691

-------
Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Number of Workers:

PPE:

Use

Paint and coating removers
liquid

Dermal contact
400-975 mg/day

CEB two hand immersion model

Stripper applied to surface by spraying or brushing or dipping. Time
given to penetrate. Stripper removed, wiped or scraped.

2,500-10,701

Respiratory and skin protection worn

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1989

Metric 5:

Sample Size

N/A





N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 No discussion on uncertainty and variability

Continued on next page

Page 254 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 255 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Manufacturing /Processing

Chemical industry and mineral oil processing - likely formulation of so-
lutions
vapor
Inhalation

0.175 (50th; below LOQ), 13.41 (90th), 16.93 (95th) mg/m3

11.0

6.0

TWA?
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Potentially contains some scenarios that are out of scope. Con-

tains some that are in scope
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 256 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 257 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Plastics and plastic foam processing/mfg

vapor

Inhalation

0.3 (50th; below LOQ), 3 (90th), 3.5 (95th) mg/m3

40.0

28.0

TWA?

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1	2

Applicability	Medium	x 2	4

Temporal Representativeness	High	x 2	2

Sample Size	Medium	x 1	2

Germany

Polymer processing is in scope, but due to unknown opera-
tions considered in this industry, this may include out of scope

scenarios

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 258 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 259 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

stones, earth, ceramics, glass industry

vapor

Inhalation

0.2 (50th; below LOQ), 0.68 (90th), 0.74 (95th) mg/m3

12.0

8.0

TWA?
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Unacceptable	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

8	Not in scope, doesn't seem applicable to those scenarios in

scope

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 260 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Occupational Exposure; Monitoring Data;

4271620

EVALUATION







Domain

Metric

Rating MWF* Score

Comments



Metric 7: Metadata Completeness

Low X 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Unacceptable 4

Metric Mean Score: 2.3.



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 261 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Mfg and processing of metals - processing of liquid coating materials

vapor

Inhalation

0.2 (50th; below LOQ), 13.41 (90th), 24.65 (95th) mg/m3

43.0

27.0

TWA?

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

Formulation of coating materials for metals

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1 3

The monitoring study does not address variability or uncer-
tainty

Continued on next page

Page 262 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	1.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 263 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Steel construction, mfg of machinery and vehicles

vapor

Inhalation

below LOD (50th), 5.02 (90th), 7.36 (95th) mg/m3

16.0

9.0

TWA?
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 264 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 265 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Electrical, fine mechanics, optics

vapor

Inhalation

0.3 (50th; below LOQ), 3.54 (90th), 6.2 (95th) mg/m3

44.0

33.0

TWA?

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 266 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 267 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

woodworking, paper, printing

vapor

Inhalation

below LOD (50th), 1 (90th), 1.7 (95th) mg/m3

40.0

23.0

TWA?

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 268 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 269 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

Painting cars

vapor

Inhalation

0.2 (50th; below LOQ), 0.5 (90th), 2.5 (95th) mg/m3

TWA?

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

Painting is in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low x 1

3

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7



Continued on next page

Page 270 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 271 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Manufacturing /Processing

Chemical industry and mineral oil processing - likely formulation of so-
lutions
vapor
Inhalation

0.45 (50th; below LOQ), 6 (90th), 9.5 (95th) mg/m3

30.0

11.0

TWA?

personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Potentially contains some scenarios that are out of scope. Con-

tains some that are in scope
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 272 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 273 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Plastics and plastic foam processinc/mfg

vapor

Inhalation

0.35 (50th; below LOQ), 2.93 (90th), 4.985 (95th) mg/m3

61.0

35.0

TWA?

personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1	2

Applicability	Medium	x 2	4

Temporal Representativeness	High	x 2	2

Sample Size	Medium	x 1	2

Germany

Polymer processing is in scope, but due to unknown opera-
tions considered in this industry, this may include out of scope

scenarios

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 274 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 275 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Mfg and processing of metals - processing of liquid coating materials

vapor

Inhalation

0.5 (50th), 2.72 (90th), 3 (95th) mg/m3
44.0
20.0
TWA?
personal
sample time > =

=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

Formulation of coating materials for metals

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1 3

The monitoring study does not address variability or uncer-
tainty

Continued on next page

Page 276 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	1.7

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 277 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Steel construction, mfg of machinery and vehicles

vapor

Inhalation

0.3 (50th; below LOQ), 1.75 (90th), 2.725 (95th) mg/m3

15.0

12.0

TWA?

personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 278 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 279 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

Electrical, fine mechanics, optics

vapor

Inhalation

below LOD (50th), 9.6 (90th), 11.9 (95th) mg/m3

21.0

15.0

TWA?

personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 280 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 281 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Processing

woodworking, paper, printing

vapor

Inhalation

0.2 (50th; below LOQ), 3.2 (90th), 12.8 (95th) mg/m3

39.0

19.0

TWA?

personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 282 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 283 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

Building industry

vapor

Inhalation

I.5	(50th), 6.6 (90th), 7.9 (95th) mg/m3

II.0
7.0

TWA?
personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	due to unknown operations considered in this industry, this

may include out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 284 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 285 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Manufacturing /Processing

Chemical industry and mineral oil processing - likely formulation of so-
lutions
vapor
Inhalation

0.45 (50th; below LOQ), 12.5 (90th), 16.8 (95th) mg/m3

30.0

11.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

2 Germany

4	Potentially contains some scenarios that are out of scope. Con-

tains some that are in scope

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Continued on next page

Page 286 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 287 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Plastics and plastic foam processinc/mfg

vapor

Inhalation

0.5 (50th), 3.45 (90th), 4.775 (95th) mg/m3

65.0

31.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

Germany

Polymer processing is in scope, but due to unknown opera-
tions considered in this industry, this may include out of scope

scenarios

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Continued on next page

Page 288 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 289 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

stones, earth, ceramics, glass industry

vapor

Inhalation

0.3 (50th; below LOQ), 0.78 (90th), 0.92 (95th) mg/m3

12.0

9.0

TWA?
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Unacceptable	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

8	Not in scope, doesn't seem applicable to those scenarios in

scope

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 290 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Occupational Exposure; Monitoring Data;

4271620

EVALUATION







Domain

Metric

Rating MWF* Score

Comments



Metric 7: Metadata Completeness

Low X 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Unacceptable 4

Metric Mean Score: 2.3.



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 291 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Mfg and processing of metals - processing of liquid coating materials

vapor

Inhalation

0.55 (50th; below LOQ), 4 (90th), 6.5 (95th) mg/m3

55.0

26.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

Formulation of coating materials for metals

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 292 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 293 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Steel construction, mfg of machinery and vehicles

vapor

Inhalation

0.55 (50th; below LOQ), 5.8 (90th), 7.45 (95th) mg/m3

15.0

10.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Continued on next page

Page 294 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 295 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Electrical, fine mechanics, optics

vapor

Inhalation

0.2 (50th; below LOQ), 3 (90th), 3.9 (95th) mg/m3

40.0

25.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 296 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 297 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

woodworking, paper, printing

vapor

Inhalation

below LOD (50th), 1 (90th), 3.855 (95th) mg/m3

33.0

23.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 298 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 299 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

woodworking, paper, printing

vapor

Inhalation

0.2 (50th; below LOQ), 2.35 (90th), 3 (95th) mg/m3

45.0

22.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 300 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 301 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Plastics and plastic foam processinc/mfg

vapor

Inhalation

0.2 (50th; below LOQ), 1.92 (90th), 2.9 (95th) mg/m3

22.0

14.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

Germany

Polymer processing is in scope, but due to unknown opera-
tions considered in this industry, this may include out of scope

scenarios

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Continued on next page

Page 302 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 303 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Mfg and processing of metals - processing of liquid coating materials

vapor

Inhalation

0.2 (50th; below LOQ), 13.45 (90th), 86.9 (95th) mg/m3

19.0

12.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

Formulation of coating materials for metals

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 304 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 305 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Steel construction, mfg of machinery and vehicles

vapor

Inhalation

below LOD

15.0

10.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Likely related to degreasing, which is in scope, but due to un-

known operations considered in this industry, this may include
out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 306 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 307 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

woodworking, paper, printing

vapor

Inhalation

below LOD (50th), 1.7 (90th), 1.74 (95th) mg/m3

33.0

23.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 308 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 309 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

woodworking, paper, printing

vapor

Inhalation

0.045 (50th; below LOQ), 28 (90th), 34 (95th) mg/m3

45.0

22.0

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 310 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 311 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

All
All

vapor
Inhalation

below LOD (50th), 0.64 (90th), 1.155 (95th) mg/m3

13.0

7.0

TWA?

storing, conveying
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	due to unknown industries for this activity, this may include

out of scope scenarios
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 312 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 313 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Processing and treatment of wood

vapor

Inhalation

below LOD (50th), 49.8 (90th), 149.8 (95th) mg/m3

24.0

9.0

TWA?

processing, sanding, removal
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Application of finishing to wood is in scope, but sanding and

removal may not be
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 314 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 315 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Processing of plastic and plastic foam

vapor

Inhalation

0.2 (50th; below LOQ), 3 (90th), 5.35 (95th) mg/m3

82.0

55.0

TWA?

surface coating and painting
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 316 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 317 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Metals, fine mechanics, optics

vapor

Inhalation

0.7 (50th), 15 (90th), 90 (95th) mg/m3

30.0

15.0

TWA?

cleaning

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 318 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 319 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Mfg of shoes; Processing of plastic and plastic foam

vapor

Inhalation

0.2 (50th; below LOQ), 3.76 (90th), 5.52 (95th) mg/m3

18.0

10.0

TWA?

gluing

area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Adhesive use is in scope, but this may also include out of scope

scenarios
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 320 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 321 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Use

Foundries

vapor

Inhalation

below LOD (50th), 15.8 (90th), 21.1 (95th) mg/m3

11.0

5.0

TWA?
area

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1	2

Unacceptable	x 2	8

High	x 2	2

Medium	x 1	2

Germany

the function in this industry is unknown

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3

The monitoring study does not address variability or uncer-
tainty

Continued on next page

Page 322 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Overall Quality Determination^	Unacceptable	4 Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 323 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Processing

Mfg of coatings, adhesives

vapor

Inhalation

0.35 (50th; below LOQ), 3.45 (90th), 5.875 (95th) mg/m3

21.0

11.0

TWA?

mixing, pressing (compacting)

Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 324 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 325 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

processing plastics and plastic

vapor

Inhalation

below LOD (50th), 0.38 (90th; below LOQ), 0.49 (95th) mg/m3

11.0

6.0

TWA?

foaming

Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium x 1

Applicability	High	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium x 1

2 Germany

2	Potentially in scope; function of NMP for plastics not well

known

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 326 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 327 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Processing and treatment of wood

vapor

Inhalation

0.5 (50th), 8.4 (90th), 13.9 (95th) mg/m3

13.0

8.0

TWA?

sanding

Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Application of finishing to wood is in scope, but sanding and

removal may not be
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 328 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 329 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Processing of plastic and plastic foam

vapor

Inhalation

0.65 (50th), 3 (90th), 4.865 (95th) mg/m3

69.0

39.0

TWA?

surface coating and painting
Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 330 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 331 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Metals, fine mechanics, optics

vapor

Inhalation

2 (50th), 12.35 (90th), 18.875 (95th) mg/m3

23.0

17.0

TWA?

cleaning

Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 332 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 333 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

Mfg of shoes; Processing of plastic and plastic foam

vapor

Inhalation

0.3 (50th; below LOQ), 1.94 (90th), 2.095 (95th) mg/m3

21

14

TWA?
gluing
Personal

sample time >=lhr; exposure duration >= 6hr

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Adhesive use is in scope, but this may also include out of scope

scenarios
2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 334 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 335 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Processing and treatment of wood

vapor

Inhalation

below LOD (50th), 5.72 (90th), 7.8 (95th) mg/m3

12

5

TWA?

sanding

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

2 Germany

4	Application of finishing to wood is in scope, but sanding and

removal may not be

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3	Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 336 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 337 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Processing of plastic and plastic foam

vapor

Inhalation

below LOD (50th), 3.24 (90th), 4.055 (95th) mg/m3

17

11

TWA?

surface coating and painting
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 338 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 339 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Metals, fine mechanics, optics

vapor

Inhalation

0.4 (50th; below LOQ), 79.6 (90th), 102.1 (95th) mg/m3

11

6

TWA?

cleaning

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 340 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 341 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Mfg of shoes; Processing of plastic and plastic foam

vapor

Inhalation

below LOD (50th), 0.2 (90th; below LOQ), 0.245 (95th; below LOQ)
mg/m3
11
7

TWA?
gluing
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken WITHOUT LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Adhesive use is in scope, but this may also include out of scope

scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 342 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 The monitoring study does not address variability or uncer-

tainty

Overall Quality Determination^	Medium	1.9

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 343 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

All
All

vapor
Inhalation

0.2 (50th; below LOQ), 0.7 (90th), 1.35 (95th) mg/m3

10

4

TWA?

storing, conveying
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

2 Germany

4	due to unknown industries for this activity, this may include

out of scope scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Monitoring data include sample type (e.g., personal breathing
zone) but lack other metadata.

Continued on next page

Page 344 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 345 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Processing

Mfg of coatings, adhesives

vapor

Inhalation

below LOD (50th), 3.45 (90th), 5.875 (95th) mg/m3

21

9

TWA?

mixing, pressing (compacting)
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 346 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 347 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

processing plastics and plastic

vapor

Inhalation

below LOD (50th), 0.88 (90th), 1.84 (95th) mg/m3

13

7

TWA?

foaming

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium x 1

Applicability	High	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium x 1

Germany

Potentially in scope; function of NMP for plastics not well
known

2010

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 348 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 349 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Processing and treatment of wood

vapor

Inhalation

below LOD (50th), 1 (90th), 1 (95th) mg/m3

14

7

TWA?

sanding

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium x 1
Medium x 2

Metric 4: Temporal Representativeness High x 2
Metric 5: Sample Size	Medium x 1

2 Germany

4	Application of finishing to wood is in scope, but sanding and

removal may not be

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3	Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 350 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 351 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Processing of plastic and plastic foam

vapor

Inhalation

0.3 (50th; below LOQ), 3.76 (90th), 5.46 (95th) mg/m3

108

68

TWA?

surface coating and painting
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 352 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 353 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Metals, fine mechanics, optics

vapor

Inhalation

0.9 (50th), 10.85 (90th), 13.125 (95th) mg/m3

35

19

TWA?

cleaning

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 354 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 355 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Mfg of shoes; Processing of plastic and plastic foam

vapor

Inhalation

0.45 (50th; below LOQ), 4.28 (90th), 6.96 (95th) mg/m3

24

13

TWA?
gluing
unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Adhesive use is in scope, but this may also include out of scope

scenarios

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 356 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 357 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

Use

Foundries

vapor

Inhalation

below LOD (50th), 0.6 (90th), 0.75 (95th) mg/m3

TWA?

unknown

sample time >=lhr; exposure duration >= 6hr
samples taken in the presence of LEV

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2:

Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Unacceptable	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

8	Not in scope, doesn"t seem applicable to those scenarios in

scope

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3

The monitoring study does not address variability or uncer-
tainty

Continued on next page

Page 358 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

Overall Quality Determination^	Unacceptable	4 Metric Mean Score: 2.3.

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 359 of 691

-------
Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Painting - manufacture and processing of metals

vapor

Inhalation

0.7 (50th),3.86 (90th), 5.415 (95th) mg/m3

TWA

Industry listed as "manufacture and processing of metals." Work group
area listed as "surface coating, painting." Unknown application type.
Unknown area of sampling. No additional details are provided,
unknown

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2010

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 360 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 361 of 691

-------
Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Cleaning - manufacture and processing of metals

vapor

Inhalation

1.5 (50th),57 (90th), 96.4 (95th) mg/m3

TWA

Industry listed as "manufacture and processing of metals." Work group
area listed as "cleaning." Unknown application type. Unknown area of
sampling. No additional details are provided,
unknown

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2010

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 362 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 363 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

woodworking, paper, printing

vapor

Inhalation

below LOD (50th), 0.46 (90th), 0.95 (95th) mg/m3

22

16

TWA

Listed as "woodworking, paper, printing",
unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope	Medium	x 1

Applicability	Medium	x 2

Temporal Representativeness	High	x 2

Sample Size	Medium	x 1

2 Germany

4	Printing is in scope. Woodworking and paper may be out of

scope.

2 2010

2	Distribution of samples is characterized by a range with uncer-

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 364 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.9





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 365 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Steel construction, manufacture of machinery and vehicles

vapor

Inhalation

0.7 (50th), 5.56 (90th), 7.36 (95th) mg/m3

16

9

TWA

Listed as "Steel construction, manufacture of machinery and vehicles."

Workgroup listed as :surface coating, painting."

unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 366 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 367 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electrical engineering, fine mechanics, optics

vapor

Inhalation

below LOD (50th), 1.22 (90th), 1.965 (95th) mg/m3

21

11

TWA

Listed as "surface coating, painting" within electrical engineering, fine
mechanics, and optics manufacturing. Additional details are not pro-
vided,
unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 368 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 369 of 691

-------
Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electrical engineering, fine mechanics, optics

vapor

Inhalation

0.95 (50th), 11.9 (90th), 12 (95th) mg/m3

TWA

Listed as "cleaning" within electrical engineering, fine mechanics, and

optics manufacturing. Additional details are not provided.

unknown

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2010

Metric 5:

Sample Size

Medium

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Low X 1 3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 370 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 371 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing

Formulation - manufacture /processing of coatings, glue, adhesives

vapor

Inhalation

0.4 below LOD (50th), 4.5 (90th), 6.2 (95th) mg/m3

14

8

TWA

Listed as "chemical industry and mineral processing," including manu-
facture /processing of coatings, glue, adhesives. Work area group listed
as "mixing, pressing." These data are likely a subset of the above data,
unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 372 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 373 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing

Manufacture /processing of plastic and plastic foam

vapor

Inhalation

0.2 below LOD (50th), 0.84 (90th), 1.72 (95th) mg/m3

14

8

TWA

Listed as "plastics and plastic foam, processing and manufacture; man-
ufacture and processing of rubber products." Work area group listed as
"Foaming." These data are likely a subset of the above data,
unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 374 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 375 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Processing

Manufacture /processing of plastic and plastic foam

vapor

Inhalation

0.3 below LOD (50th), 2 (90th), 2.6 (95th) mg/m3

28

13

TWA

Listed as "plastics and plastic foam, processing and manufacture; man-
ufacture and processing of rubber products." Work area group listed as
"Surface coating, painting, coating." These data are likely a subset of
the above data,
unknown

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology not specified as NIOSH or
OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Continued on next page

Page 376 of 691

-------
— continued from previous page

Source Citation: IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 4271620

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 377 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use
Gluing
vapor
Inhalation

0.85 (50th), 6.15 (90th), 8.625 (95th) mg/m3

15

8

TWA

Work group area is listed as "Gluing." No additional details are provided,
unknown

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

Low

X

2

6

unknown if in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer-
tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1 3

The monitoring study does not address variability or uncer-
tainty

Continued on next page

Page 378 of 691

-------
— continued from previous page

Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	Medium	2.1

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 379 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

woodworking, paper, printing

vapor

Inhalation

50th percentile: below analytical quantification limit of 0.4290th per-
centile: 6.7695th percentile: 26
28
17

TWA

Listed as "woodworking, paper, printing"
area

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 380 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 381 of 691

-------
Source Citation:	IFA. 2010. MEGA evaluations for the preparation of REACH exposure scenarios for N-methyl-2-pyrrolidone (vapour).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	4271620

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

woodworking, paper, printing

vapor

Inhalation

50th percentile: below analytical quantification limit of 0.4290th per-
centile: 12.5695th percentile: 120.6
14
9

TWA

Listed as "woodworking, paper, printing"
personal

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 Sampling or analytical methodology not specified as NIOSH or

OSHA, but seems acceptable.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X

1

2

Germany

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2010

Metric 5:

Sample Size

Medium

X

1

2

Distribution of samples is characterized by a range with uncer

tain statistics.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Monitoring data include sample type (e.g., personal breathing

zone) but lack other metadata.

Domain 4: Variability and Uncertainty

Continued on next page

Page 382 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

IFA. 2010. MEGA evaluations for the preparation of REACH exposure

Occupational Exposure; Monitoring Data;

4271620

scenarios for N-methyl-2-pyrrolidone (vapour).

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Metric 7; Metadata Completeness

Low

x 1 3

The monitoring study does not address variability or uncer-
tainty

Overall Quality Determination^

Medium

1.7





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 383 of 691

-------
Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

spray application of coating

Inhalation

0.04-5.2 mg/m3

unknown

1

unknown

workers inside spray booth

personal

unknown

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	High	x 1	1

Applicability	High	x 2	2

Temporal Representativeness	Low	x 2	6

Sample Size	Medium	x 1	2

US

in scope

1996

characterized by a range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 384 of 691

-------
— continued from previous page

Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 385 of 691

-------
Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

spray application of coating

Inhalation

0.04-0.62 mg/m3

unknown

1

unknown

workers outside spray booth

personal

unknown

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	High	x 1	1

Applicability	High	x 2	2

Temporal Representativeness	Low	x 2	6

Sample Size	Medium	x 1	2

US

in scope

1996

characterized by a range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 386 of 691

-------
— continued from previous page

Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 387 of 691

-------
Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

spray application of coating

Inhalation

18.6 101 mg/m3

unknown

1

unknown

inside spray booth
area

unknown

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1996

Metric 5:

Sample Size

Medium

X

1

2

characterized by a range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 388 of 691

-------
— continued from previous page

Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 389 of 691

-------
Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Use

spray application of coating

Inhalation

0.04-0.81 mg/m3

unknown

1

unknown

outside spray booth
area

unknown

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1996

Metric 5:

Sample Size

Medium

X

1

2

characterized by a range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

High



1.6

Continued on next page

Page 390 of 691

-------
— continued from previous page

Source Citation:	NIOSH. 1998. Health Hazard Evaluation Report No. HETA 9602662702, Cooper Engineered Products, Bowling Green, Ohio.

Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	4287129

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 391 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.0057- <0.083 ppm TWA: <0.0057 -
<0.006 ppm
5

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Container change out: various sizes
Personal
2-20 minutes

55- gallon drum change outs can occur once every other week to 16 times
in a 12-hour shift

Typical chemical delivery systems are enclosed units equipped with local
exhaust ventilation, leak detection, and exhaust monitoring with alarm
to a central control room or personnel.

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; OSHA PV2043, SOP-5, GC-FID; mod. NIOSH 1302

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Continued on next page

Page 392 of 691

-------
— continued from previous page

Source Citation:

Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

5161295

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 393 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.0023 - <3 ppm TWA: <0.08 - <0.762
ppm

15

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Container change out: various sizes
Personal
2-20 minutes

55- gallon drum change outs can occur once every other week to 16 times in
a 12-hour shift

Typical chemical delivery systems are enclosed units equipped with local
exhaust ventilation, leak detection, and exhaust monitoring with alarm
to a central control room or personnel.

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; OSHA PV2043, SOP-5, GC-FID; mod. NIOSH 1302

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Continued on next page

Page 394 of 691

-------
— continued from previous page

Source Citation:

Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

5161295

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 395 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.2 - <0.39 ppm TWA: <0.011 -
<0.19 ppm
12

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Container change out: various sizes
Personal
2-20 minutes

55- gallon drum change outs can occur once every other week to 16 times
in a 12-hour shift

Typical chemical delivery systems are enclosed units equipped with local
exhaust ventilation, leak detection, and exhaust monitoring with alarm
to a central control room or personnel.

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; OSHA PV2043, SOP-5, GC-FID; mod. NIOSH 1302

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Continued on next page

Page 396 of 691

-------
— continued from previous page

Source Citation:

Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

5161295

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 397 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.9 ppmTWA: <0.1 ppm
1

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Container changeout and waste handling: NOWPAK bladder removal
prior to disposal.

Personal
2-20 minutes

55- gallon drum changeouts can occur once every other week to 16 times
in a 12-hour shift

Typical chemical delivery systems are enclosed units equipped with local
exhaust ventilation, leak detection, and exhaust monitoring with alarm
to a central control room or personnel.

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; OSHA PV2043, SOP-5, GC-FID; mod. NIOSH 1302

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Continued on next page

Page 398 of 691

-------
— continued from previous page

Source Citation:

Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

5161295

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 399 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.49 ppm TWA: <0.013 ppm
1

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Container change out and waste handling: Waste drum Disconnect, Re-
moval, Handling (55 gal)

Personal
2-20 minutes

55- gallon drum change outs can occur once every other week to 16 times
in a 12-hour shift

Typical chemical delivery systems are enclosed units equipped with local
exhaust ventilation, leak detection, and exhaust monitoring with alarm
to a central control room or personnel.

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; OSHA PV2043, SOP-5, GC-FID; mod. NIOSH 1302

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Continued on next page

Page 400 of 691

-------
— continued from previous page

Source Citation:

Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

5161295

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 401 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.006 - <0.20 ppm TWA: <0.0057-
<0.20 ppm
18

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Maintenance activities: Plate cleans, filter changes, tool PMs, tool clean-
ing, o-ring change out
Personal

The task takes from less than 12 minutes to less than or equal to 2 hours
Performed fewer than 1 time per month per tool

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1:

Methodology

High x 1 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:

Geographic Scope

High x 1 1

US

Continued on next page

Page 402 of 691

-------
— continued from previous page

Source Citation: Semiconductor Industry Association (SIA).
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score

Comments

Metric 3;
Metric 4:
Metric 5;

Applicability

Temporal Representativeness
Sample Size

High
High
High

X
X
X

2
2
1

2
2
1

In scope

Data from 2018

Discrete data points provided

Domain 3; Accessibility/Clarity

Metric 6; Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7; Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^

High





1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 403 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.024 - 0.29 ppm TWA: <0.001-<0.13 ppm
12

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Maintenance activities
Personal

The task takes from less than 12 minutes to less than or equal to 2 hours
Performed fewer than 1 time per month per tool

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2
Metric 3
Metric 4

Geographic Scope	High x 1	1 US

Applicability	High x 2	2 in scope

Temporal Representativeness High x 2	2 Data from 2018

Continued on next page

Page 404 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score Comments



Metric 5; Sample Size

High

x 1

1 Discrete data points provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1 Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 well characterized

Overall Quality Determination^

High



1.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 405 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.18 - <1 ppm TWA: <0.003 - <0.18
ppm 9

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Maintenance activities: Tool PMs and dip tube change out on chem de-
livery system
Personal

The task takes from less than 12 minutes to less than or equal to 2 hours
Performed fewer than 1 time per month per tool

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2: Geographic Scope	High x 1	1 US

Metric 3: Applicability	High x 2	2 In scope

Continued on next page

Page 406 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score

Comments



Metric 4: Temporal Representativeness
Metric 5; Sample Size

High
High

x 2
x 1

2
1

Data from 2018

Discrete data points provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 407 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.2 - <1 ppm TWA: <0.0095 - <0.37
6

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Maintenance activities: wet station clean and parts clean using 100

percent NMP

Personal

The task takes from less than 12 minutes to less than or equal to 2 hours
Performed fewert han 1 time per month per tool; 1-4 times/month
Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2: Geographic Scope	High x 1	1 US

Metric 3: Applicability	High x 2	2 In scope

Continued on next page

Page 408 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score

Comments



Metric 4: Temporal Representativeness
Metric 5; Sample Size

High
High

x 2
x 1

2
1

Data from 2018

Discrete data points provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 409 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.0038 - <0.20 ppm TWA: <0.0036 - <0.20
28

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Fab Worker: Production operators of tools using NMP and maintenance

technicians

Personal and area

Fab operators and technicians typically work in the fab 10.5 hours of a

12-hour shift.

Daily

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID; OSHA 7

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1:

Methodology

High x 1 1

Sampling or analytical methodology is an approved OSHA or
NIOSH method

Domain 2: Representative
Metric 2:

Geographic Scope

High x 1 1

US

Continued on next page

Page 410 of 691

-------
— continued from previous page

Source Citation: Semiconductor Industry Association (SIA).
Type of Data Source Occupational Exposure; Monitoring Data;
Hero ID 5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score

Comments

Metric 3;
Metric 4:
Metric 5;

Applicability

Temporal Representativeness
Sample Size

High
High
High

X
X
X

2
2
1

2
2
1

In scope

Data from 2018

Discrete data points provided

Domain 3; Accessibility/Clarity

Metric 6; Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7; Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^

High





1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 411 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured Exposure Range: <0.013 - <0.14 ppm TWA: N/A
9

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Fab Area Monitoring (near tools that use NMP in process)

Personal and area

Fab operators and technicians typically work in the fab 10.5 hours of a

12-hour shift.

Daily

Semiconductor fab workers wear long sleeved coveralls with hoods and
boots as well as gloves and safety glasses that provide ?98 percent
skin coverage. Personal protective equipment such as chemical resis-
tant aprons and gloves, face shields, and respiratory protection are used
when necessary to further reduce worker exposure.

NIOSH 1302; mod. NIOSH 1302 - GC/FID; PV2043; OSHA PV2043 -
SOP-5, GC-FID; OSHA 7

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2: Geographic Scope	High x 1	1 US

Metric 3: Applicability	High x 2	2 In scope

Continued on next page

Page 412 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score

Comments



Metric 4: Temporal Representativeness
Metric 5; Sample Size

High
High

x 2
x 1

2
1

Data from 2018

Discrete data points provided

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 413 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured: <0.4 ppm TWA: <0.35 ppm

1

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Waste truck loading: Transfer of approximately 5,000 gallons of NMP

waste from a 10,000 gallon tank to a tanker truck.

Personal

2	to 4 hours

Tasks are performed by one employee and the truck driver. The employee
wears safety glasses and face shield, PVC apron with sleeves, long pants
and work boots, and Trionic gloves,
mod. NIOSH 1302 - GC/FID BADGE

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5:

Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity

Continued on next page

Page 414 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION

Domain

Metric

Rating MWF*

Score Comments



Metric 6; Metadata Completeness

High

x 1

1 Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 well characterized

Overall Quality Determination^

High



1.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 415 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5161295

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:
Exposure Duration:
PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Measured: 1.2 ppmTWA: 1.18 ppm

1

14 total sites sampled in study
Full shift TWA (8 or 12 hours)

Virgin NMP truck off-loading: Pull 6 samples for purity analysis; trans-
fer of virgin NMP from a 10,000 gallon tanker truck to a 10,000 gallon
tank in the tank farm. Turn on pump; stay in enclosure upstairs during

2	hour transfer.

Personal

2 to 4 hours

Tasks are performed by one employee and the truck driver. The employee
wears safety glasses and face shield, PVC apron with sleeves, long pants
and work boots, and Trionic gloves,
mod. NIOSH 1302 - GC/FID BADGE

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Sampling or analytical methodology is an approved OSHA or











NIOSH method

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2

Data from 2018

Metric 5:

Sample Size

High

x 1

1

Discrete data points provided

Continued on next page

Page 416 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Semiconductor Industry Association (SIA).
Occupational Exposure; Monitoring Data;
5161295

2019.

NMP Supplemental Data: Container Handling.

EVALUATION











Domain

Metric

Rating MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 417 of 691

-------
Source Citation:

Kemira. 2018. RE: N-Methylpyrrolidone (NMP) (CASRN 872-50-4). EPA-HQ-OPPT-2016-0743-0085.

Type of Data Source

Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

5176404

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Chemical processing, excluding formulation (polymer manufacturing)

PPE:	chemical resistant jacket, gloves, goggles and a face shield

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

No Comment.

Overall Quality Determination^	High	1.1

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 418 of 691

-------
Source Citation:	FUJIFILM Electronics Materials USA Inc.. 2017. NMP Use/Application Survey FFEM/FEUP. EPA-HQ-OPPT-2016-0743-

0024.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176406

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics - semiconductor manufacturing

Enclosed process; In many cases, operations are conducted in class 100
or class 10 clean rooms.

Safety Glasses, impervious gloves, protective clothing with respirators if
required

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

No Comment.

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 419 of 691

-------
Source Citation: Saft American Inc.. 2017. Memorandum to EPA: N-methylpyrrolidone, docket ID number EPA-HQ-OPPT-2016-0743. EPA-

HQ-OPPT-2016-0743-0005.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176407

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Worker Activity:

Engineering Control & percent Exposure Reduction:
PPE:

Use

Electronics - batteries

Workers may also be potentially exposed during dilution, mixing, or

sampling of solutions containing NMP,

totally or partially enclosed and equipped with ventilation

face shields, gloves, and chemical resistant clothing

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 420 of 691

-------
Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

Range: less than the detection limit to 0.202 mg/m3

unknown

unknown

full-shift TWA

Wafer stripping ("cleaning") removing photoresist. Wafer cleaning for
organics removal. Operations are in a closed processing system,
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Methodology is stated and seems legitimate

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

EU

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2003 - 2011

Metric 5:

Sample Size

Medium

x 1

2

range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 lacks exposure duration and frequency

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 limited discussion

Continued on next page

Page 421 of 691

-------
— continued from previous page

Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 422 of 691

-------
Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

Range: 0.0247 to 0.857 mg/m3

unknown

unknown

full-shift TWA

Photolithography layer spin-on.
in a closed processing system,
personal

Polyimide deposition. Operations are

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Methodology is stated and seems legitimate

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

EU

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2003 - 2011

Metric 5:

Sample Size

Medium

x 1

2

range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 lacks exposure duration and frequency

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 limited discussion

Continued on next page

Page 423 of 691

-------
— continued from previous page

Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 424 of 691

-------
Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

Range: less than the detection limit to 0.770 mg/m3

unknown

unknown

full-shift TWA

Preventive maintenance at process equipment tools in the cleanroom.

Invasive maintenance.

personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Methodology is stated and seems legitimate

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

EU

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2003 - 2011

Metric 5:

Sample Size

Medium

x 1

2

range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 lacks exposure duration and frequency

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 limited discussion

Continued on next page

Page 425 of 691

-------
— continued from previous page

Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 426 of 691

-------
Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

Range: less than the detection limit to 4.054 mg/m3

unknown

unknown

full-shift TWA

Chemicals storage and delivery areas open to ambient air. Canister,
bottle and container change at tools and chemfill stations not in the
cleanroom.
personal

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Methodology is stated and seems legitimate

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

EU

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

4

2003 - 2011

Metric 5:

Sample Size

Medium

x 1

2

range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium x 1	2 lacks exposure duration and frequency

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 limited discussion

Continued on next page

Page 427 of 691

-------
— continued from previous page

Source Citation:	North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176408

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 428 of 691

-------
Source Citation: Celanese Engineered Materials. 2017. N-methylpyrrolidone (NMP) CASRN: 872-50-4, use, disposal and exposure scenarios.

EPA-HQ-OPPT-2016-0743-0015.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176410

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Engineering Control & percent Exposure Reduction:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
Exposure scenarios include: 1. Exposure to vapors when the NMP bot-
toms waste stream is dumped into a hopper to cool or when the hoppers
are being dumped into roll off boxes.; 2. Line breaking activities for
maintenance personnel. PPE is defined.; 3. Other fugitive emission
exposure during sampling, lab analysis or in the event of a leak.

NMP is used in a contained system in which all vapors are collected in
vent systems and burned in a thermal oxidizer. Destruction efficiency of
the thermal oxidizer is >99.9 percent .

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2017

Metric 5:

Sample Size

N/A

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness N/A N/A No Comment.

Continued on next page

Page 429 of 691

-------
— continued from previous page

Source Citation:	Celanese Engineered Materials. 2017. N-methylpyrrolidone (NMP) CASRN: 872-50-4, use, disposal and exposure scenarios.

EPA-HQ-OPPT-2016-0743-0015.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176410

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 430 of 691

-------
Source Citation:	Akin Gump Strauss Hauer & Feld LLP. 2018. Re: EPA docket EPA-HQ-OPPT-2016-0743: N-Methyl-2-pyrrolidone ("NMP"),

CAS# 872-50-4 comments regarding the NMP problem formulation document. EPA-HQ-OPPT-2016-0743-0102.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176411

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Engineering Control & percent Exposure Reduction:

PPE:

Use

dip cleaning of plastic films

Vapor

Inhalation

Occupational exposure levels to NMP through inhalation range from neg-
ligible to approximately 4 ppm
8-hour TWA

scrubbers or a Regenerative Thermal Oxidizer (RTO)

Neoprene gloves, long sleeve cotton uniforms with pants and/or coveralls,
safety shoes, and safety glasses. Face shields and safety goggles along
with chemical resistant aprons are utilized for tasks with liquid splash
potential

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Low

X 1

3

Sampling or analytical methodology is not specified.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2

2018

Metric 5:

Sample Size

Low

x 1

3

qualitative or characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable x 1

Monitoring data do not include any needed metadata to un-
derstand what the data represent - i.e., PBZ or Area, Num. of
samples, worker activities

Continued on next page

Page 431 of 691

-------
— continued from previous page

Source Citation:	Akin Gump Strauss Hauer & Feld LLP. 2018. Re: EPA docket EPA-HQ-OPPT-2016-0743: N-Methyl-2-pyrrolidone ("NMP"),

CAS# 872-50-4 comments regarding the NMP problem formulation document. EPA-HQ-OPPT-2016-0743-0102.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	5176411

EVALUATION





Domain Metric

Rating

MWF* Score Comments

Domain 4: Variability and Uncertainty





Metric 7: Metadata Completeness

Low

X 1 3 does not address variability or uncertainty

Overall Quality Determination^

Unacceptable

4 Metric Mean Score: 2.0.



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 432 of 691

-------
Source Citation: American Chemistry Council. 2017. American Chemistry Council comments on the U.S. Environmental Protection Agency's

initial 10 chemicals identified for risk evaluation. EPA-HQ-OPPT-2016-0743-0011.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176412

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Paints, coatings, adhesives

Engineering Control & percent Exposure Reduction: The products are batch manufactured in an enclosed process. The pro-

cess vents to a carbon absorber. During the compounding process, the
blend vessel is closed.
PPE: Full face respirators

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

ACC poll of trade association members. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

No Comment.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

No Comment.

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 433 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):
Number of Samples:

Number of Sites:

Type of Measurement or Method:
Worker Activity:

Type of Sampling:

Use

vapor

Inhalation

ND - 7.745 ppm

174

short-term measurements and full-shift

All Other Converted Paper Product Mfg.; All Other Misc. Wood Prod-
uct Mfg.; All Other Plastics Product Mfg.; All Other Rubber Prod-
uct Mfg.; Fabric Coating Mills; Iron Foundries; Landscaping Services;
Metal Coating, Engraving (Except Jewelry and Silverware), and Allied
Services to Manufacturers; Metal Kitchen Cookware, Utensil, Cutlery,
and Flatware (Except Precious) Mfg.; Photographic and Photocopying
Equipment Mfg.
personal and area

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

High
Medium

Metric 4: Temporal Representativeness Low

X 1 1 Data collected in the United States

X 2 4 These conditions of use are unknown but likely fall within the

scope

x 2 6 Samples collected in 1984 to 1999. Data are more than 20 years

old.

Continued on next page

Page 434 of 691

-------


— continued from

previous

page



Source Citation:
Type of Data Source
Hero ID

OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Occupational Exposure; Monitoring Data;

3827305

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments



Metric 5; Sample Size

High

X 1

1

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

X 1

2

OSHA data include sample type and exposure type. Sample
times also provided.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

OSHA data do not address variability or uncertainty

Overall Quality Determination^

Medium



2.0





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 435 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):
Number of Samples:

Number of Sites:

Type of Measurement or Method:
Worker Activity:

Type of Sampling:

Use

vapor

Inhalation

ND - 1.54 ppm

short-term measurements and full-shift

Administration of Education Programs; Institutional Furniture Manu-
facturing; Nonferrous Metal (Except Copper and Aluminum) Rolling,
Drawing, and Extruding; Other Industrial Machinery Mfg.; Printing
Machinery and Equipment Mfg.
personal and area

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

Medium

These conditions of use are unknown but likely fall within the
scope

Samples collected in 2000 to 2001. Data are more than 10 years
old but not more than 20 years old.

Metric 4:

Temporal Representativeness

Medium

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Continued on next page

Page 436 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Occupational Exposure; Monitoring Data;

3827305

EVALUATION

Domain

Metric Rating

MWF*

Score

Comments



Metric 6; Metadata Completeness Medium

X 1

2

OSHA data include sample type and exposure type. Sample
times also provided.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low

X 1

3

OSHA data do not address variability or uncertainty

Overall Quality Determination^ Medium



1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 437 of 691

-------
Source Citation:	OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3827305

EXTRACTION

Parameter	Data

Life Cycle Stage:

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):
Number of Samples:

Number of Sites:

Type of Measurement or Method:
Worker Activity:

Type of Sampling:

Use

vapor

Inhalation

ND - 2.52 ppm

19

6

short-term measurements and full-shift

All Other Miscellaneous Fabricated Metal Product Manufacturing;
Metal Coating, Engraving (except Jewelry and Silverware), and Allied
Services to Manufacturers; Regulation, Licensing, and Inspection of Mis-
cellaneous Commercial Sectors; Reupholstery and Furniture Repair; Sign
Manufacturing
personal and area

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	X 1	1 OSHA and state inspectors are expected to use OSHA or

NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

Data collected in the United States

Metric 3:

Applicability

Medium

X

2

4

These conditions of use are unknown but likely fall within the
scope

Samples collected in 2011 to 2019. Data are less than 10 years
old.

Metric 4:

Temporal Representativeness

High

X

2

2

Metric 5:

Sample Size

High

X

1

1

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Continued on next page

Page 438 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Occupational Exposure; Monitoring Data;

3827305

EVALUATION

Domain

Metric Rating

MWF*

Score

Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium

X 1

2

OSHA data include sample type and exposure type. Sample
times also provided.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low

X 1

3

OSHA data do not address variability or uncertainty

Overall Quality Determination^ High



1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 439 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Printing

vapor

Inhalation

ND (5 samples); 0.2637 ppm

short-term

Commercial Printing (Except Screen and Books)
personal

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

Medium

Samples collected in 2000 to 2001. Data are more than 10 years
old but not more than 20 years old.

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can

be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Continued on next page

Page 440 of 691

-------
— continued from previous page

Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

High

1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 441 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

0.37 - 13.84 ppm

Full-shift

Capacitor, Resistor, Coil, Transformer,
personal

and Other Inductor Mfg.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

High

Samples collected in 2007. Data are not more than 10 years
old (measured from start of project, 2016).

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can

be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Continued on next page

Page 442 of 691

-------
— continued from previous page

Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

High

1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 443 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

short-term measurements

Bare Printed Circuit Board Mfg

personal

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

Medium

Samples collected in 2000. Data are more than 10 years old
but not more than 20 years old.

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Continued on next page

Page 444 of 691

-------
— continued from previous page

Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

High

1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 445 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Electronics

vapor

Inhalation

short-term measurements and full-shift
Semiconductor and Related Device Mfg.
personal

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

Medium

Samples collected in 1998. Data are more than 10 years old but
not more than 20 years old (measured from start of project,
2016).

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Continued on next page

Page 446 of 691

-------
— continued from previous page

Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.
Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Domain 4; Variability and Uncertainty

Metric 7; Metadata Completeness

Low

X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

High

1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 447 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Cleaning

vapor

Inhalation

0.153, 0.203, 0.59 ppm

short-term measurements
Janitorial Services
personal

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

OSHA and state inspectors are expected to use OSHA or
NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

Low

Samples collected in 1992. Data are more than 20 years old.

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can

be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Domain 4: Variability and Uncertainty

Continued on next page

Page 448 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Occupational Exposure; Monitoring Data;

3827305

EVALUATION

Domain

Metric

Rating

MWF* Score Comments



Metric 7; Metadata Completeness

Low

X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

Medium

1.8



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 449 of 691

-------
Source Citation: OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3827305

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Use

Pesticides

vapor

Inhalation

short-term measurements
Exterminating and Pest Control Services
personal

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High

X 1 1 OSHA and state inspectors are expected to use OSHA or

NIOSH sampling methods. Samples sent to the OSHA SLTC
are expected to be analyzed using OSHA or NIOSH analytical
methods.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

Unacceptable

This is a non-TSCA use

Metric 4:

Temporal Representativeness

Low

Samples collected in 1988. Data are more than 20 years old.

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness Medium X 1 2 OSHA data include sample type and exposure type. Sample

times also provided.

Domain 4: Variability and Uncertainty

Continued on next page

Page 450 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

OSHA. 2017. Chemical Exposure Health Data (CEHD) provided by OSHA to EPA.

Occupational Exposure; Monitoring Data;

3827305

EVALUATION

Domain

Metric

Rating MWF* Score Comments



Metric 7: Metadata Completeness

Low X 1 3 OSHA data do not address variability or uncertainty

Overall Quality Determination^

Unacceptable 4 Metric Mean Score: 2.4.



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 451 of 691

-------
Source Citation: FUJIFILM Holdings America Corporation. 2020. FUJIFILM comments for docket ID # EPA-HQ-OPPT-2019-0236 for

CASRN 872-50-4, n-methylpyrrolidone (NMP).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 6592030

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Engineering Control & percent Exposure Reduction:
PPE:

Processing

Formulation into solutions for electronics industry

vapor

Inhalation

ND (14 samples), 0.23 ppm, 0.86 ppm

full-shift measurements

Lab technician (analytical work) and tote filling
personal

Enclosed processes. Hood. LEV.

PPE required - the gloves in use are Showa brand #3416: neoprene-
coated, 15-mil thickness, and 14-inch gauntlet cuff with interlock knit
lining. Safety glasses. Chemical hygiene training on a scheduled basis
and use of PPE are a requisite condition of employment and prior to
first use of NMP and all other chemicals in the facility.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Low X 1 3 Sampling or analytical methodology is not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Data collected in the United States

Metric 3:

Applicability

High

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

High

Samples collected in 2019. Data are less than 10 years old.

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Continued on next page

Page 452 of 691

-------
— continued from previous page

Source Citation:	FUJIFILM Holdings America Corporation. 2020. FUJIFILM comments for docket ID # EPA-HQ-OPPT-2019-0236 for

CASRN 872-50-4, n-methylpyrrolidone (NMP).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	6592030

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

X 1

2

These data include sample type and exposure type. Sample
times also provided.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

These data do not address variability or uncertainty

Overall Quality Determination^

High



1.6





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 453 of 691

-------
Source Citation: LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 6592033

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics manufacturing - Lithium Ion Battery

vapor

Inhalation

ND - 9.8 ppm

full-shift measurements (8-hour TWA)

cathode coating; cathode mixing; cleaning; fill room; maintenance; mix

room; research and development

personal

Total exposure would be on the order of minutes rather than hours
Lithium ion cells are produced in a tightly controlled manufacturing
environment and closed pipe systems are used for NMP transfer. Dry
room design to prevent absorption of water. All NMP tanks with the
exception of the slurry tanks, are equipped with a nitrogen blanketing
system as a measure to protect the quality of the NMP.

Full coverage PPE. NMP-resistant butyl rubber gloves. Personnel work-
ing in mixing and coating areas receive extensive training regarding the
processes and proper PPE. Additional PPE is provided for work that will
involve contact or potential contact with NMP and includes chemical re-
sistant suits, respirators, and chemical resistant gloves, depending on the
task performed. These workers are required to wear full body chemical
resistant suit with booties/shoe covers. The equipment includes a PAPR
and hood with organic/acid gas + HEPA cartridge coverage. Gloves are
required, typically double latex for limited contact with NMP. Butyl
gloves are required when contact with NMP is expected, (pg. 15-16)

EVALUATION

Domain Metric Rating MWF* Score Comments

Continued on next page

Page 454 of 691

-------
— continued from previous page

Source Citation: LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 6592033

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

Sampling or analytical methodology is not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:

Geographic Scope
Applicability

Temporal Representativeness

High
High
High

XXX

2
2

Data collected in the United States
This occupational condition of use is in scope
Samples collected in 2011 to 2019. Data are less than 10 years

Metric 5:

Sample Size

High

Individual measurements are provided so the sample sets can
be fully statistically characterized.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

These data include sample type and exposure type. Sample
times also provided.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

These data do not address variability or uncertainty

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 455 of 691

-------
Source Citation:	EaglePicher Technologies, LLC. 2020. Comments of EaglePicher Technologies, LLC on the draft TSCA risk evaluation of

n-methylpyrrolidone (NMP): EPA"HQ"OPPT-2019-0236.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592029

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Exposure Duration:

Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics manufacturing - Lithium Ion Battery

At no time do any EaglePicher employees come into direct dermal con-
tact with NMP. Employees infrequently work with NMP, as our batch
manufacturing process only occurs periodically. Activities with NMP
include mixing, transfer the blended binder mix and clean a small tank,
total time for all activities combined is less than 2.5 hours
Blending and application of coating (containing NMP) occurs in a closed
system. After coating, the parts are dried in an oven (NMP evaporates)
with a capture system that vents all the emissions outside.

Protective clothing, gloves specifically designed to protect against NMP
exposure, respirators, and goggles/face-shields, employees wear PPE with
an assigned protection factor (APF) of 1,000 that precludes in-halation or
dermal contact.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information from manufacturer of lithium ion batteries,
bias /errors evident.

No

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Continued on next page

Page 456 of 691

-------
— continued from previous page

Source Citation:	EaglePicher Technologies, LLC. 2020. Comments of EaglePicher Technologies, LLC on the draft TSCA risk evaluation of

n-methylpyrrolidone (NMP): EPA"HQ"OPPT-2019-0236.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592029

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 457 of 691

-------
Source Citation: EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592024

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Exposure Concentration (Unit):

Worker Activity:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:
PPE:

Use

Electronics manufacturing - Lithium Ion Battery
Direct hand/skin contact does not occur.

Cathode slurry mixing. Maintenance - equipment cleaning and repair.
Small container unloading: 1-gallon containers (only applicable to small
sites). NMP unloading at large sites is done by the vendor. Drum han-
dling - for some small scale operations, waste disposal includes pouring
small quantities of residual into closed 50-gallon drum
30 mins (mixing); 4 hours (Maintenance); 30 mins (small container un-
loading); 1 hour (drum handling)

250 day/yr (mixing); infrequent - few times/year (maintenance); infre-
quent - couple weeks per year (drum handling)

Small sites: NMP containers are opened and mixed under an engineering
hood. Large sites: enclosed process. Fume hoods, fume extractors, jigs.
Mixing: Light Tyvek, Safety glasses, Nitrile gloves, Safety shoes, Surgical
mask, Hairnet and bump cap. Donning procedures and rooms with
training. //Maintenance: Heavy Tyvek /or aprons, PAPR or respirator
/goggles, Heavy butyl gloves over lighter gloves, Safety shoes. Donning
procedures and rooms with training. //Small container: Goggles /face
shield, Butyl gloves over nitrile, Aprons. Donning procedures and rooms
with training.

EVALUATION

Domain

Metric

Rating

MWF*

Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2 Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:

Geographic Scope

High

X 1

1 US

Continued on next page

Page 458 of 691

-------
— continued from previous page

Source Citation:	EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592024

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 3: Applicability

Metric 4: Temporal Representativeness

Metric 5: Sample Size

High
High
Medium

XXX

2
2
1

2
2
2

This occupational condition of use is in scope
2020

Exposure duration provided as single value. Uncertain statis-
tics and uncertain if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X

1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X

1

3

Does not address variability or uncertainty

Overall Quality Determination^

High





1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 459 of 691

-------
Source Citation: EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592024

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Exposure Concentration (Unit):

Worker Activity:

Exposure Frequency:

PPE:

Use

Electronics manufacturing - Lithium Ion Battery
No potential for dermal contact due to PPE usage.

Small sealed containers. Drums,
intermittent

For slurry materials: Tyvek Suit, Protective Gloves, Shoe Covers, Safety
glasses, Hair net, beard net and face mask. When powders involved:
PAPR (Powered Air Purifying Respirator) with a HEPA filter instead
of hair net, beard net and face mask. Are trained on proper glove use.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

This occupational condition of use is in scope
2020

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4

Continued on next page

Page 460 of 691

-------
— continued from previous page

Source Citation:	EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592024

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 461 of 691

-------
Source Citation:	LICM. 2020. Supplemental NMP information to document PPE protection for submission to docket from Lithium Ion Cell

Manufacturers. EPA-HQ-OPPT-2016-0743-0116.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592044

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Exposure Concentration (Unit):

Worker Activity:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics manufacturing - Lithium Ion Battery

There is no actual exposure to NMP during any of these tasks due to
engineering controls and PPE.

Container Handling, Small Containers - including manual transfers
and mixing preparation //Container Handling, Drums - loading waste
material into drums //Batch mixing; Batch coating and drying //
Maintenance activities //occupational non-user exposures - NMP used
in secured area. Process and safety checks and walk-throughs occur.
30 - 60 mins/day (small containers) //30 - 60 mins/month (drums) //2-
6 hours/day (small operations); 12-hr shifts (large operations) (mixing)
//60 mins/month (maintenance; ONUs)

daily (small containers, mixing); monthly (drums, maintenance, ONUs)
Small operations: Closed systems, some process piping, ventilation con-
trols. //Large operations: Fully automated systems - closed reactors,
process piping, ventilation controls, manufacturing one or few types of
cells. Semi-automated systems - same as above but greater operational
flexibility needed, manufacturing different cell types. //Additional con-
trols provided for each activity.

Small operations: Latex (no expected exposure; PPE to prevent product
contamination). Safety glasses, lab coat, and surgical mask. //Large
operations: Fully automated systems - nitrile (no expected exposure;
PPE to prevent product contamination). Light Tyvek, safety glasses,
safety shoes, surgical mask, hairnet, and bump cap. Semi-automated
systems - butyl over latex or nitrile (no expected exposure; PPE to
prevent product contamination). PAPR with hood and organic vapor/
acid gas/HEPA combination cartridge. //Additional PPE provided for
each activity.

EVALUATION

Continued on next page

Page 462 of 691

-------
— continued from previous page

Source Citation: LICM. 2020. Supplemental NMP information to document PPE protection for submission to docket from Lithium Ion Cell

Manufacturers. EPA-HQ-OPPT-2016-0743-0116.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592044

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

2
2
2

This occupational condition of use is in scope
2020

Exposure duration provided as single value or range. Uncertain
statistics and uncertain if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 463 of 691

-------
Source Citation: Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID 3986801

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Type of Sampling:

Exposure Duration:

Exposure Frequency:

Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics semiconductors

Vapor

Inhalation

Same monitoring data as 5161295

118.0

14.0

Full shift TWA (8 or 12 hours)

Same activities as 5161295 (described further on page 6).

Personal

Same as 5161295; Fab operators and technicians typically work in the
fab 10.5 hours of a 12-hour shift.

Same as 5161295; Waste truck loading (follow-up on 5161295): 1/yr
The fabrication of semiconductors is conducted in specialized build-
ings known as "fabs" that involve the use of cleanrooms, and a hier-
archy of design features that isolate workers and the product wafers
from chemicals and contaminants. Exhaust ventilation. Modern high-
volume manufacturing fabs use enclosed, interlocked, ventilated, and
automated manufacturing equipment (tools) which separate employees
from the product wafer and process chemicals.

Fab workers wear cleanroom garments (cleanroom suit with hood and
boots), gloves, and safety glasses (see Figure 2) which provide ?98 per-
cent skin coverage. Activity-specific PPE same as 5161295. Workers have
appropriate training, including on donning and doffing gloves.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High X 1 1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Continued on next page

Page 464 of 691

-------
— continued from previous page

Source Citation:	Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	3986801

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5: Sample Size

High

X

1

1

Discrete data points provided

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

High

X

1

1

well characterized

Overall Quality Determination^	High	1.0

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 465 of 691

-------
Source Citation:	Intel Corporation. 2019. Intel comments to: Science Advisory Committee on Chemicals (SACC) on the draft Toxic Substances

Control Act (TSCA) risk evaluation for N-Methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0037.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592026

EXTRACTION

Parameter	Data

Use

of Use):	Electronics semiconductors

vapor, liquid
Inhalation, dermal

container change out, maintenance, routine operations
Chemical resistant PPE is always required for any tasks where there
is potential for skin contact. PPE includes Chemical Resistant Gloves,
Chemical Resistant Gown, Chemical Goggles, Face Shield. Source de-
scribes PPE training received by employees, including when PPE is re-
quired, what PPE is required, and proper donning and doffing.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

This occupational condition of use is in scope
2019

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 Does not address variability or uncertainty

Life Cycle Stage:

Life Cycle Description (Subcategory

Physical Form:

Route of Exposure:

Worker Activity:

PPE:

Continued on next page

Page 466 of 691

-------
— continued from previous page

Source Citation:	Intel Corporation. 2019. Intel comments to: Science Advisory Committee on Chemicals (SACC) on the draft Toxic Substances

Control Act (TSCA) risk evaluation for N-Methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0037.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592026

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 467 of 691

-------
Source Citation:	Intel Corporation. 2020. Comments of Intel to the United States Environmental Protection Agency on the draft Toxic

Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone. EPA-HQ-OPPT-2019-0236-0064.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	6592034

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Engineering Control & percent Exposure Reduction:

PPE:

Analytic Method:

Use

Electronics semiconductors

Vapor

Inhalation

Same monitoring data as 5161295

Engineering controls include the use of bulk chemical delivery to reduce
manual handling of chemical containers, lockout/tagout to turn off bulk
chemical supplies prior to equipment maintenance, flushing of filters and
housing prior to work, integrated local ventilation exhaust on manufac-
turing equipment, liquid leak detection systems, use of ventilated parts
clean sinks or hoods for parts cleaning, and emergency machine off sys-
tems.

The current PPE required is: MAPA8 Trionic 514+ (or equivalent)
chemical resistant gloves3, chemical resistant gowns, and eye and face
protection. Employees receive training on proper PPE usage.

NIOSH 1302; OSHA PV2043

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High X 1	1 Sampling or analytical methodology is an approved OSHA or

NIOSH method

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

Data from 2018

Metric 5:

Sample Size

High

X

1

1

Discrete data points provided

Continued on next page

Page 468 of 691

-------
— continued from previous page

Source Citation:	Intel Corporation. 2020. Comments of Intel to the United States Environmental Protection Agency on the draft Toxic

Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone. EPA-HQ-OPPT-2019-0236-0064.

Type of Data Source Occupational Exposure; Monitoring Data;

Hero ID	6592034

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Raw data provided and is well-described by metadata

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 469 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:
PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.511 mg/m3 (central tendency); 0.613 mg/m3 (High-
end) Dermal surface area: 24.08 cm2 (male) and 20.03 cm2 (female) (cen-
tral tendency); 80.25 cm2 (male) and 66.75 cm2 (female) (high-end)Daily
dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/cm2 (high-
end)

PBPK model inputs

container handling, small containers

Dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-
end) Task durations as low as 5 to 10 minutes

3 days/week over 50 weeks/yr (central tendency); 4 days/week over 50
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative
Metric 2
Metric 3
Metric 4

Geographic Scope	High x 1	1 US

Applicability	High	x 2	2 in scope

Temporal Representativeness High x 2 2 2020

Continued on next page

Page 470 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 5: Sample Size

Medium

X 1

2

Inputs characterized as central tendency and high-end. Un-
clear if these inputs are representative of all semiconductor
manufacturing sites.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 471 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.013 mg/m3 (central tendency); 1.557 mg/m3 (High-
end)Dermal surface area: 24.08 cm2 (male) and 20.03 cm2 (female) (cen-
tral tendency); 80.25 cm2 (male) and 66.75 cm2 (female) (high-end)Daily
dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/cm2 (high-
end)

PBPK model inputs
container handling, drums

dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-end)
3 days/week over 50 weeks/yr (central tendency); 4 days/week over 50
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Continued on next page

Page 472 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 473 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.139 mg/m3 (central tendency); 0.409 mg/m3 (High-
end)Dermal surface area: 0 cm2 (male and femal, central tendency and
high-end)

PBPK model inputs
typical fab worker
0 hrs of dermal exposure

3 days/week over 50 weeks/yr (central tendency); 4 days/week over 50
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Domain 3: Accessibility/Clarity

Continued on next page

Page 474 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 475 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.139 mg/m3 (central tendency); 0.409 mg/m3 (High-
end)Dermal surface area: 24.08 cm2 (male) and 20.03 cm2 (female) (cen-
tral tendency); 80.25 cm2 (male) and 66.75 cm2 (female) (high-end)Daily
dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/cm2 (high-
end)

PBPK model inputs

fab worker with NMP container changeout

dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-end)
3 days/week over 50 weeks/yr (central tendency); 4 days/week over 50
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Continued on next page

Page 476 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 477 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.020 mg/m3 (central tendency); 0.696 mg/m3 (High-
end)Dermal surface area: 267.50 cm2 (male) and 222.50 cm2 (female)
(central tendency); 374.50 cm2 (male) and 311.50 cm2 (female) (high-
end)Daily dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/
cm2 (high-end)

PBPK model inputs
maintenance

dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-end)
3 days/week over 50 weeks/yr (central tendency); 4 days/week over 50
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Continued on next page

Page 478 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 479 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:

Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 4.822 mg/m3 (central tendency); 4.822 mg/m3 (High-

end)Dermal surface area: 80.25 cm2 (male) and 66.75 cm2 (female)

(central tendency); 267.50 cm2 (male) and 22.50 cm2 (female) (high-

end)Daily dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/

cm2 (high-end)

PBPK model inputs

virgin NMP truck unloading

dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-end)
1 day/week over 1 week/yr (central tendency and high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Continued on next page

Page 480 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 481 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Type of Measurement or Method:
Worker Activity:

Exposure Duration:

Exposure Frequency:

PPE:

Use

Electronics semiconductors
vapor, liquid
Inhalation, dermal

Air concentration: 0.715 mg/m3 (central tendency); 0.715 mg/m3 (High-
end)Dermal surface area: 80.25 cm2 (male) and 66.75 cm2 (female)
(central tendency); 267.50 cm2 (male) and 22.50 cm2 (female) (high-
end)Daily dermal loading: 0.7 mg/cm2 (central tendency) and 2.1 mg/
cm2 (high-end)

PBPK model inputs
waste truck loading

dermal exposure duration: 0.33 hrs (central tendency); 1 hour (high-end)
1 day/week over 12 weeks/yr (central tendency); 1 day/week over 17.3
weeks/yr (high-end)

Gloves with Protection Factor of 20. Additional information on type of
PPE used and employee training.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Assessment uses data from member companies of trade associ-
ation. Information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

Medium

X

1

2

Inputs characterized as central tendency and high-end. Un

clear if these inputs are representative of all semiconductor
manufacturing sites.

Continued on next page

Page 482 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Occupational Exposure; Completed Exposure or Risk Assessments;

Hero ID	6592032

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1

1

The assessment addresses variability and uncertainty in the
results. Uncertainty is well characterized.

Overall Quality Determination^

High



1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 483 of 691

-------
Source Citation:	Hach Company. 2020. Hach's comments regarding the draft Toxic Substances Control Act (TSCA) risk evaluation for

n-methylpyrrolidone (NMP), EPA docket EPA-HQ-OPPT-2019-0236.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592027

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

PPE:

Processing
Formulation

In small-scale incorporation of NMP into a mixture, NMP is transferred
from hand-held containers, such as a 1-gallon container, to the mixing
vessel. Fewer than 10 gallons per day of NMP are handled.

Workers are required to wear the following personal protective equip-
ment: gloves (laminate film, latex at least 20 mil thickness, or butyl at
least 20 mil thickness); safety glasses for operations in fume hood, or
splash goggles; fume hood or half-face or full-face respirator.

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

XXX

1

2
2

1

2
2

N/A

US

This occupational condition of use is in scope
2020

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X

1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X

1

3

Does not address variability or uncertainty

Overall Quality Determination^

High





1.4





Continued on next

page





Page 484 of 691

-------
— continued from previous page

Source Citation:	Hach Company. 2020. Hach's comments regarding the draft Toxic Substances Control Act (TSCA) risk evaluation for

n-methylpyrrolidone (NMP), EPA docket EPA-HQ-OPPT-2019-0236.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592027

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 485 of 691

-------
Source Citation: National Electrical Manufacturers Association. 2020. NMP use in magnet wire. EPA-HQ-OPPT-2019-0236-0047.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592028

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Worker Activity:

Engineering Control & percent Exposure Reduction:

PPE:

Use

Electronics - magnet wires

Magnet wire coating. Equipment cleaning.

The polymer applicator and curing oven are completely enclosed and
there is no human exposure to NMP during this process. This process
is also completely enclosed while equipment is cleaned.

Human exposure to NMP is controlled through the use of personal pro-
tection equipment such as gloves, aprons and goggles.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

This occupational condition of use is in scope
2020

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 486 of 691

-------
Source Citation:
Type of Data Source
Hero ID

ACA. 2020. American Coatings Association submittal to NMP docket: EPA-HQ-2016-0743.

Occupational Exposure; Monitoring Data;

6592043

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Physical Form:

Route of Exposure:

Exposure Concentration (Unit):

Number of Samples:

Number of Sites:

Type of Measurement or Method:

Worker Activity:

Number of Workers:

Type of Sampling:

Exposure Duration:

Engineering Control & percent Exposure Reduction:
PPE:

Analytic Method:

Processing

Formulation of paint

vapor

inhalation

<0.091 ppm

1.0

1.0

TWA

Paint formulation - Employee working in WB small batch loading to
504. Worked at solvent bath SRI for < 10 min washing a wand.

1.0

personal

sample time: 375 mins (6.25 hours)

Local Exhaust and General Exhaust

Nitrile and Hyflex Gloves, Safety Glasses, Goggles, Nomex protective
clothing

Sample method: SO-3, GC-FID NIOSH 1550

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X

1

1

Sampling methodology is an approved NIOSH method

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2018

Metric 5:

Sample Size

Low

X

1

3

One sample result provided. Distribution of samples is un-

known.

Continued on next page

Page 487 of 691

-------
— continued from previous page

Source Citation:

ACA. 2020. American Coatings Association submittal to NMP docket: EPA-HQ-2016-0743.

Type of Data Source

Occupational Exposure; Monitoring Data;

Hero ID

6592043

EVALUATION



Domain

Metric Rating MWF* Score Comments

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 Monitoring data include same type, exposure type, and du-

ration. Data do not include exposure duration, exposure
frequency, or detailed worker activities.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3 Does not address variability or uncertainty

Overall Quality Determination^

High



1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 488 of 691

-------
Source Citation: LICM. 2020. Supplemental NMP information to document PPE protection for submission to docket from Lithium Ion Cell

Manufacturers. EPA-HQ-OPPT-2016-0743-0116.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592044

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Worker Activity:

Engineering Control & percent Exposure Reduction:
PPE:

Use

Electronics - lithium ion battery

For small operations, NMP is received in one-gallon containers that are
securely stored until they are carefully transferred to the mixing room. In
some circumstances, small operators perform a controlled transfer from
a small bottle of waste containing NMP into a 55-gallon drum, using
an industrial-grade funnel with a sealable lid and spill containment.
In other circumstances, small operators place sealed small bottles into
a 55-gallon drum. The drums are then torqued to seal them and
taken on a drum dolly to a secure storage location until a third-party
vendor loads the drums onto a truck for disposal.

Extensive engineering controls exist within large operations to prevent
worker contact with NMP and NMP-containing slurry.

The selection of protective glove materials is based on the recommenda-
tions of leading glove manufacturers. Workers are trained in PPE usage.
Instruction in PPE is augmented by signage in the workplace, dedicated
stations to don PPE, and the use of mixing air showers before entry into
secured production areas. Information on NMP breakthrough times for
various gloves and PPE training materials are provided.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

This occupational condition of use is in scope

Metric 4:

Temporal Representativeness

High

x 2

2020

Continued on next page

Page 489 of 691

-------
— continued from previous page

Source Citation:	LICM. 2020. Supplemental NMP information to document PPE protection for submission to docket from Lithium Ion Cell

Manufacturers. EPA-HQ-OPPT-2016-0743-0116.

Type of Data Source Occupational Exposure; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592044

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 5: Sample Size

N/A



N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 490 of 691

-------
Facility

Page 491 of 691

-------
Source Citation:

Cory, N. J.. 2002. An update on environmental constraints. American Leather Chemists Association. Journal.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

2874538

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Polymer solvent; leather finishing

Process Description: NMP is used as a solvent for urethane polymerization. It is found in

residual concentrations in polyurethane coatings used for leather
finishing. NMP has been found in auto leather at concentrations up to
averaging 3,000 mg/kg. Studies on boot leather have demonstrated
significantly-lower NMP concentrations ranging from 200 to 600 mg/kg.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

The data, data sources, and/or techniques used in the assess-
ment or report are not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Low

X
X
X
X

2
2
1

2
4

In scope
2002

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

Assessment or report does not document its data sources, as-
sessment methods, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

The report does not address variability or uncertainty.

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.2.

Continued on next page

Page 492 of 691

-------
— continued from previous page

Source Citation:	Cory, N. J.. 2002. An update on environmental constraints. American Leather Chemists Association. Journal.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	2874538

EVALUATION

Domain	Metric	Rating	MWF* Score	Comments

** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 493 of 691

-------
Source Citation: Solomon, G. M.,Morse, E. P.,Garbo, M. J.,Milton, D. K.. 1996. Stillbirth after occupational exposure to N-methyl-2-

pyrrolidone: A case report and review of the literature. Journal of Occupational and Environmental Medicine.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3043623

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Laboratory

Process Description:
Batch Size:

NMP used to dissolve solid samples (negative photoresist), which is an-
alyzed in atomic absorption spectrophotometers, and discarded as Haz
waste. NMP first poured from 5 gallon containers through an ion ex-
change column for filtering before use. Custom chemical manufacturer.
1 L/day

EVALUATION

Domain

Metric

Rating MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium X 1 2 From an industry contact

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Use is in scope

Metric 4:

Temporal Representativeness

Low

1996 - more than 20 years old

Metric 5:

Sample Size

Low

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High x 1

1 Discussion on variability and uncertainty of results

Overall Quality Determination^

Medium

1.8

* MWF = Metric Weighting Factor

Page 494 of 691

-------
Source Citation: Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3539720

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Possible Physical Form:
Chemical Concentration:

Use

Adhesive formulation facility

NMP was applied for the manual cleaning of mixing and stirring vessels
(500 1 volume) and of smaller parts such as drain valves and tools. After
the mixing of the basic compounds ( 2 h), the vessels are emptied and the
stirrers and upper parts of the mixers are cleaned manually with brushes
and wiping cloths. The vessels are then disassembled and cleaned for
about 30 min with brushes and cloths together with inlets, drain valves
and other fittings,
liquid
65 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From an industry contact

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X 1

Germany

Metric 3:

Applicability

High

x 2

Use is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

2006

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low X 1 3 Does not address variability or uncertainty.

Continued on next page

Page 495 of 691

-------
— continued from previous page

Source Citation:	Bader, M.,Rosenberger, W.,Rebe, T.,Keener, S. A.,Brock, T. H.,Hemmerling, H. J.,Wrbitzky, R.. 2006. Ambient moni-

toring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. International Archives of
Occupational and Environmental Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3539720

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 496 of 691

-------
Source Citation: Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3562767

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Degreasing optical lenses

The lenses were washed in a room with a large washing chamber (1 m x I
m x 2.5 m). Four workers were engaged in the washing process. Fifty
lenses were put in a special container basket. Workers opened a door of
the chamber to dip the basket into a pool containing NMP inside the
chamber. After closing the door, sonication was started to wash the
lens surfaces. This washing process lasted for 5 min. After washing, the
baskets were lifted from the pool and then dried outside the chamber for a
couple of minutes.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From an industry contact

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X 1

Japan

Metric 3:

Applicability

High

x 2

Degreasing is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

2000

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low X 1 3 Does not address variability or uncertainty.

Continued on next page

Page 497 of 691

-------
— continued from previous page

Source Citation:	Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3562767

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 498 of 691

-------
Source Citation: Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3562767

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Degreasing metal parts

They put more than 100 parts in a basket, opened the cover of a tank
containing NMP and dumped the basket into the tank. The lid of the
container was then closed. After 30 min of soaking in NMP, the basket
was lifted out and immediately transferred to a tank containing water.
Some drops adhering to the parts and baskets were scattered over the
floor. Other drops were carried into the water tank. NMP evaporated
into the washing room air from the contaminated floor and water tank.
Eight workers were engaged in this process.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From an industry contact

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X 1

Japan

Metric 3:

Applicability

High

x 2

Degreasing is in scope

Metric 4:

Temporal Representativeness

Medium

x 2

2000

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low X 1 3 Does not address variability or uncertainty.

Continued on next page

Page 499 of 691

-------
— continued from previous page

Source Citation:	Xiaofei, E.,Wada, Y.,Nozaki, J.,Miyauchi, H.,Tanaka, S.,Seki, Y.,Koizumi, A.. 2000. A linear pharmacokinetic model predicts

usefulness of N-methyl-2-pyrrolidone (NMP) in plasma or urine as a biomarker for biological monitoring for NMP exposure.
Journal of Occupational Health.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3562767

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 500 of 691

-------
Source Citation: Muenter, J., Blach, R.. 2010. ECOLOGICAL TECHNOLOGY: NMP-FREE LEATHER FINISHING. American

Leather Chemists Association. Journal.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3577026

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Coating - polymeric for leather finishing

NMP eased the production of binders and the application on lemher.
NMP influences the viscosity and even the rheology. When NMP is
used in leather finishing almost 90 percent remains in the leather after
drying, but is gradually released over a long period of time.
0-7.1 percent

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Germany

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2010

Metric 5:

Sample Size

Medium

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Medium

Assessment or report clearly documents results, methods, and

assumptions. Data sources are generally described but not

fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness High X 1 1 The report addresses variability and uncertainty in the results.

Uncertainty is well characterized

Continued on next page

Page 501 of 691

-------
— continued from previous page

Source Citation:

Type of Data Source
Hero ID

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	High	1.4

Muenter, J.,Blach, R.. 2010. ECOLOGICAL TECHNOLOGY: NMP-FREE LEATHER FINISHING. American Leather
Chemists Association. Journal.

Facility; Reports for Data or Information Other than Exposure or Release Data;

3577026

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 502 of 691

-------
Source Citation: Lammens, T. M., Potting, J., Sanders, J. P. M., De Boer, I. J. M.. 2012. Environmental comparison of biobased chemicals

from glutamic acid with their petrochemical equivalents. International Sugar Journal.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3578330

EXTRACTION

Parameter Data

Life Cycle Stage: Manufacture

Life Cycle Description (Subcategory of Use): Manufacturing

Total Annual U.S. Volume (and percent of PV): 100-150 kton

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Information from journal articles

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Low

X 1

x 2
x 2
x 1

Manufacturing is in scope
2010

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

Does not address variability or uncertainty for this data ele-
ment

Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor

Page 503 of 691

-------
Source Citation: Eu,. 2007. Impact assessment of potential restrictions on the marketing and use of dichloromethane in paint strippers. Revised

final report-Annexes.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3808951

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Paint stripper

Paint strippers are used to remove various coats of paints especially
blistered or cracked coats on wood both indoors and outdoors. NMP
cannot be used for polyester or baked on coatings.

2.5-63 percent

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

x 1

Trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium x 1

High x 2

Medium x 2

Medium x 1

2 OECD member states

2 in scope

4 2007

2 Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High X 1 1 Assessment or report clearly documents its data sources, as-

sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1 The report addresses variability and uncertainty in the results.
Uncertainty is well characterized

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 504 of 691

-------
Source Citation: ECHA. 2011. Annex XV dossier. Proposal for Identification of a Substance as a CMR Cat 1A or IB, PBT, vPvB or a

Substance of an Equivalent Level of Concern.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3809417

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Processing

Chemical processing, excluding formulation (petrochemical extraction)
NMP is used in the large-scale recovery of hydrocarbons by extractive
distillation. Hydrocarbons are highly soluble in NMP and differences in
volatility are sometimes considerably increased in the presence of NMP
(BASF, 2010). NMP is used particularly because, unlike other commer-
cial solvents and extraction media, its use does not lead to the formation
of azeotropeslO and because NMP has high resistance to heat and chem-
icals.

Based on data from OECD (2007), historical use in this application was
estimated as 10 percent of global use. If the same is true for current use
in the EU, the total use in this application could be around 1,000 -5,000

t/y.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology High x 1 1 ECHA

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Europe

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2011

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data sources included

Domain 4: Variability and Uncertainty

Continued on next page

Page 505 of 691

-------
— continued from previous page

Source Citation:	ECHA. 2011. Annex XV dossier. Proposal for Identification of a Substance as a CMR Cat 1A or IB, PBT, vPvB or a

Substance of an Equivalent Level of Concern.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3809417

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

N/A

N/A This metric is not applicable to this data type

Overall Quality Determination^

High

1.1



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 506 of 691

-------
Source Citation: ECHA. 2011. Annex XV dossier. Proposal for Identification of a Substance as a CMR Cat 1A or IB, PBT, vPvB or a

Substance of an Equivalent Level of Concern.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3809417

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Processing

Chemical processing, excluding formulation (pharmaceutical extraction
medium)

According to the OECD (2009) SIDS dossier, NMP is used as a pen-
etration enhancer for a more rapid transfer of substances through the
skin. Use as a solvent and extraction medium is reported by indus-
try (Taminco, 2010). There is limited information that suggests NMP
could be used as a solvent during the preparation of pharmaceuticals as
well as being present in some pharmaceutical products (Jouyban et al,
2010). These authors state that NMP is one of the main pharmaceutical
co-solvents and that it is an important solvent used in the extraction,
purification and crystallisation of drugs. It is not known whether NMP
is used in this way within the EU.

No comprehensive information is available on quantities of NMP cur-
rently used in the EU in pharmaceuticals. However, based on the global-
level percentage split of uses from several years ago (15 percent ) and
the assumed quantity used in the EU (10,000 -50,000 t/y), it can be
estimated that perhaps 1,500 to 7,500 tonnes of NMP are used in this
application each year.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

High

ECHA

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

Europe

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2011

Continued on next page

Page 507 of 691

-------
— continued from previous page

Source Citation:	ECHA. 2011. Annex XV dossier. Proposal for Identification of a Substance as a CMR Cat 1A or IB, PBT, vPvB or a

Substance of an Equivalent Level of Concern.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3809417

EVALUATION







Domain Metric

Rating

MWF* Score

Comments

Metric 5: Sample Size

N/A

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1 1

Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 508 of 691

-------
Source Citation:
Type of Data Source
Hero ID

A. L. Harreus, R. Backes, J. O. Eichloer, R. Feuerhake, C. Jakel, U. Mahn, R. Pinkos, R. Vogelsang. 2011. 2-Pyrrolidone.

Facility; Reports for Data or Information Other than Exposure or Release Data;

3809424

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Possible Physical Form:
Chemical Concentration:

Manufacture
Manufacture

Large-scale production of NMP is predominantly carried out by reacting
?-butyrolactone with an excess of pure or aqueous methylamine in a high-
pressure tube reactor (612 MPa). The reaction is exothermic and often
run under adiabatic conditions with reactor temperatures in the range of
250400 "C. The resulting product mixture is decompressed and distilled.
The NMP yield is normally more than 97 percent [27]. Other processes,
e.g., analogous to those used for pyrrolidone synthesis can also be used, in
particular hydrogenation of N-methylsuccinimide or mixtures of maleic
or succinic anhydride and methylamine [28]. NMP can also be produced
by hydrogenation of N-hydroxymethyl- 2-pyrrolidone (see Chap. 2) [29]
or by reaction of acrylonitrile with methylamine in the presence of a
peroxide radical initiator [30].
liquid

NMP content, min.99.5 wt percent ; methylamine, max. 0.02 wt
percent; water, max. 0.1 wt percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Ullmann's Encyclopedia of Industrial Chemistry

Domain 2: Representative

Metric 2:

Geographic Scope

Medium

X 1

Germany

Metric 3:

Applicability

High

x 2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2011

Metric 5:

Sample Size

Medium

x 1

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Continued on next page

Page 509 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

A. L. Harreus, R. Backes, J. O. Eichloer, R. Feuerhake, C. Jakel, U. Mahn, R. Pinkos, R. Vogelsang. 2011. 2-Pyrrolidone.

Facility; Reports for Data or Information Other than Exposure or Release Data;

3809424

EVALUATION

Domain

Metric

Rating

MWF* Score Comments



Metric 6; Metadata Completeness

High

X 1 1 Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

X 1 2 Limited information on concentration variability

Overall Quality Determination^

High

1.3



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 510 of 691

-------
Source Citation:

Nicnas,. 2013. Human health Tier II assessment for 2-pyrrolidinone, 1-methyl, CAS Number 872-50-4.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3809432

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Domestic paint and varnish remover

Chemical Concentration:	up to 100 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
Low

High

N/A

X 1

x 2
x 2

1

6

2

N/A

US

a non-occupational scenario that is similar to an occupational
scenario

2011-2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Does not address variability or uncertainty for this data ele-
ment

Overall Quality Determination^

Medium



1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 511 of 691

-------
Source Citation:	Nicnas,. 2013. Human health Tier II assessment for 2-pyrrolidinone, 1-methyl, CAS Number 872-50-4.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3809432

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Domestic cleaning products

Chemical Concentration:	5 percent

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

Low

X

2

6

a non-occupational scenario that is similar to an occupational
scenario

Metric 4:

Temporal Representativeness

High

X

2

2

2011-2017

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 Does not address variability or uncertainty for this data ele-
ment

Overall Quality Determination^

Medium

1.8



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 512 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Facility; Completed Exposure or Risk Assessments;

3809440

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Manufacture
Manufacturing

The production of NMP and associated bulk transfers and storage is
contained within closed systems. Processes involved are the use in
closed systems (PROC1-2-3), the transfer of NMP after production
(charging and discharging, see below under generic use), sampling and
maintenance and cleaning.

60,000 80,000 tonnes/yr
3 US Sites (2007)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative











Metric 2:

Geographic Scope

Low

X 1

3

Europe

Metric 3:

Applicability

High

x 2

2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2013

Metric 5:

Sample Size

Low

x 1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

High

x 1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 513 of 691

-------
Source Citation: Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID 3809440

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Processing
Formulation

mixing in batch or continuous processes and further processing steps
such as transfers, storage and packing. Such processes might occur in
closed systems. In the industrial setting elevated temperatures can be
used.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

Low

Europe

Metric 3:

Applicability

High

in scope

Metric 4:

Temporal Representativeness

High

2013

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

High

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

Page 514 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Petrochemical

NMP is used in the large-scale recovery of hydrocarbons by extractive
distillation. Hydrocarbons are highly soluble in NMP. NMP is used in
the desulfurization of oil products, the removal of C02, COS and H2S
from gas streams and in butadiene production.

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 515 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Use

Coatings, Paints, adhesive, varnish, etc.

NMP is used as a solvent in a wide range of different coating products.
NMP is often used in polymer based coatings, such as wire coatings.
The characteristics are favorable for baked coatings that are cured at
relatively high temperatures (BASF, 2010). The use in coatings may be
under elevated temperatures up to 120 "C. The processes involved in the
use of non-wire coatings are in general open processes involving dipping,
rolling, spraying and curing/drying of the coatings.

2,220-4,280 tonnes/yr (Europe)

0.06 13 (paint); 13 68 (paint remover); 0.06 2 (polish); 1-10 (adhesive)

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High x 1

Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

Low

X

1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High x 1	1 Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High X 1	1 Discussion on variability and uncertainty

Continued on next page

Page 516 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Rivm,. 2013. Annex XV Restriction Report: Proposal for a
Facility; Completed Exposure or Risk Assessments;

3809440

Restriction.



EVALUATION

Domain

Metric Rating MWF*

Score

Comments

Overall Quality Determination^ High

1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 517 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Facility; Completed Exposure or Risk Assessments;

3809440

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Use

Cleaning

NMP is used as an ingredient in paint removers, cleaners and as or in
degreasers. It can be used in pure form or in mixtures. Industrially, it
can be used under elevated temperatures.

60-95 tonnes/yr
30-60 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Information from trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

Low

X 1

Europe

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

High

x 2

2013

Metric 5:

Sample Size

Low

x 1

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

x 1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

High

x 1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 518 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

Cleaning and coating in the Electronics industry

Wafer cleaning and stripping to remove organic contamination and organic
layers. And, as a solvent in dedicated formulations (i.e., precursor solutions
for wafer coatings such as polyimides and anti-reflective coatings).
<5 tonnes/yr

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

Low

X

1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 519 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

Electronics

A photoresist carrier solvent. A photoresist stripper.
10-100 tonnes/yr per site

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

Low

X

1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 520 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Battery

In lithium battery production it is applied as a solvent for the binder
resins for both the carbon anode and the lithium cobalt oxide cathode, it
may be used in gel-polymer lithium ion battery separators/electrolytes,
and it may be used in coatings on the outside of the batteries.

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative













Metric 2:

Geographic Scope

Low

X

1

3

Europe

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2013

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 521 of 691

-------
Source Citation:

Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source

Facility; Completed Exposure or Risk Assessments;

Hero ID

3809440

EXTRACTION

Parameter

Data

Life Cycle Stage: Processing

Life Cycle Description (Subcategory of Use): Polymers

Process Description: NMP is used as a processing aid in the production of polymers. Immer-

sion precipitation in a solvent. Up to and including polymerization, this
use can be considered as a controlled process, though not fully closed,
but after polymerization, the resultant polymer still contains traces of
NMP that may evaporate during the production process and may cause
worker exposure. The high performance polymer end product is assumed
not to contain any remaining NMP.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

Information from trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High

N/A

X
X
X

2
2

3
2
2

N/A

Europe
in scope
2013

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

Discussion on variability and uncertainty

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

Page 522 of 691

-------
Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Processing

Agricultural products

NMP is both used in the synthesis of active ingredients and as a co-
solvent in the formulation of various agrochemicals. In case NMP is
used in the synthesis of active ingredients, the use is fully industrial and
NMP is assumed not end up in the final product. If NMP is used as a
co-solvent, NMP will obviously be contained in the final products. The
concentration of NMP in herbicides, fungicides and pesticides is < 7
percent .

1-15 (pesticide)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

Information from trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High
Medium

X 1

x 2
x 2
x 1

3
2
2
2

Europe
in scope
2013

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High



1.3



Continued on next page

Page 523 of 691

-------
— continued from previous page

Source Citation:	Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3809440

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 524 of 691

-------
Source Citation:

Rivm,. 2013. Annex XV Restriction Report: Proposal for a Restriction.

Type of Data Source

Facility; Completed Exposure or Risk Assessments;

Hero ID

3809440

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Pharmaceutical

Process Description:	In the production of pharmaceuticals, NMP is an important solvent used

in the extraction, purification, and crystallization of pharmaceuticals
(Jouyban et al 2010). BASF (2011a) further reports that it produces
high grade NMP. A number of topical formulations that may contain
NMP as a transdermal enhancer. Also the use as a solvent and as ex-
traction medium

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X

1

1

Information from trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High

N/A

X
X
X

1

2
2

3
2
2

N/A

Europe
in scope
2013

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X

1

1

Data sources are transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X

1

1

Discussion on variability and uncertainty

Overall Quality Determination^

High





1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 525 of 691

-------
Source Citation: Ec/Hc,. 2017. Chemicals at a glance: NMP and NEP.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3827463

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

All
All

NMP is used in industrial applications, as well as in products available to
consumers, including paint strippers, cosmetics, and certain food packag-
ing materials. Canadians may be exposed to these substances primarily
through products used by consumers, such as paint strippers, nail polish
remover and body lotion.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

The data, data sources, and/or techniques used in the assess-
ment or report are not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium
Unacceptable
High
N/A

X 1

x 2
x 2

2
8
2

N/A

Canada

Not enough information to assess applicability
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

data sources are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

no discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.6.

Continued on next

page

Page 526 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Ec/Hc,. 2017. Chemicals at a glance: NMP and NEP.

Facility; Reports for Data or Information Other than Exposure or Release Data;
3827463



EVALUATION

Domain

Metric Rating MWF* Score

Comments



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 527 of 691

-------
Source Citation: U.S, E. P. A.. 1998. Environmental profile for N-methylpyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3827493

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Manufacture
Manufacture

See Section 2.1. N-methylpyrrolidone is manufactured by combining y-
butyrolactone with methylamine. NMP production is accomplished by
condensing y-butyrolactone with methylamine at 200 to 350" C and 10
MPa.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

x 1

The assessment or report uses data or techniques that are high

quality (from trusted sources (e.g., journal articles)

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

in scope

Metric 4:

Temporal Representativeness

Medium

x 2

1998

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x 1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

The report provides only limited discussion of the variability
and uncertainty in the results.

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 528 of 691

-------
Source Citation:

U.S, E. P. A.. 1998. Environmental profile for N-methylpyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3827493

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Paint stripper

Chemical Concentration: 12-80 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

The assessment or report uses data or techniques that are high
quality (from trusted sources (e.g., journal articles)

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Medium

X
X
X
X

2
2
1

2
4
2

in scope
1998

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

The report provides only limited discussion of the variability
and uncertainty in the results.

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 529 of 691

-------
Source Citation:

U.S, E. P. A.. 1998. Environmental profile for N-methylpyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3827493

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): photoresist remover

Process Description: N-methylpyrrolidone is used in the microelectronics industry to strip

phenolic residue from packages and photoresist resins on wafer surfaces
and as a vehicle for "die-coat" application.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

The assessment or report uses data or techniques that are high
quality (from trusted sources (e.g., journal articles)

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

XXX

2
2

2
4

N/A

in scope
1998

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

The report provides only limited discussion of the variability
and uncertainty in the results.

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 530 of 691

-------
Source Citation:

U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source

Facility; Completed Exposure or Risk Assessments;

Hero ID

3827504

EXTRACTION



Parameter

Data

Life Cycle Stage:	Manufacture

Life Cycle Description (Subcategory of Use):	Manufacture or import

Total Annual U.S. Volume (and percent of PV):	184.7 million pounds

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

Data and techniques are high quality; Information from trusted
sources.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Low

X 1

x 2
x 2
x 1

1

2

2

3

US

in scope
2012-2015

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 531 of 691

-------
Source Citation:	U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source Facility; Completed Exposure or Risk Assessments;

Hero ID	3827504

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Possible Physical Form:
Chemical Concentration:

Use

Paint stripper

Larger facilities typically purchase in quantities ranging in size from five-
to 55-gallon drums. Smaller facilities purchase small quantities of strip-
per from hardware or paint supply stores. Techniques for paint stripping
typically include manual coating, tank dipping and spray application.
Pouring, wiping and rolling are also possible application techniques and
application can be manual or automated. After application, the strip-
per is allowed to set and soften the old coating. Once the stripper has
finished setting, the old coating is removed from the surface by scraping
and brushing. After the old coating is removed, the surface is wiped
clean before moving to the next stages of the job.

9 percent

In California, approximately 80 facilities that have stripping equipment.
500 additional facilities in the state, which would include small facilities
like antique shops
liquid

0.25 (low-end), 0.625 (mid), 1 (high-end)

EVALUATION













Domain

Metric

Rating

MWF*

Score



Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X 1

1

Data and techniques

are high quality; Information from trusted











sources.



Domain 2: Representative













Metric 2:

Geographic Scope

High

X 1

1

US



Metric 3:

Applicability

High

x 2

2

in scope



Metric 4:

Temporal Representativeness

High

x 2

2

2012-2015



Metric 5:

Sample Size

Low

x 1

3

Characterized by no

statistics

Continued on next page

Page 532 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Facility; Completed Exposure or Risk Assessments;

3827504

EVALUATION









Domain

Metric

Rating

MWF* Score

Comments



Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1 1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

X 1 1

well characterized

Overall Quality Determination^

High

1.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 533 of 691

-------
Source Citation:

U.S, E. P. A.. 2015. TSCA work plan chemical risk assessment. N-Methylpyrrolidone: Paint stripper use (CASRN: 872-50-4).

Type of Data Source

Facility; Completed Exposure or Risk Assessments;

Hero ID

3827504

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): graffiti removal

Process Description: Solvents are either spray or brush applied. Sprayed solvents can be

swabbed or wiped with a cloth or tissue. After spraying and wiping
or brushing the solvent on the surface, the surface is then washed with
heated (70oC) wash water using a high-pressure spray.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

Data and techniques are high quality; Information from trusted
sources.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X
X
X

2
2

N/A

in scope with paint stripping
2012-2015

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

well characterized

Overall Quality Determination^

High

1.0

* MWF = Metric Weighting Factor

Page 534 of 691

-------
Source Citation:

Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3828838

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Manufacture of dyes and pigment

Process Description:	see pages 73-79 for basic, not NMP-specific process description

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

OECD
in scope
2011

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 535 of 691

-------
Source Citation:

Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3828838

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	pesticides, fertilizers and nitrogen compounds

Process Description:	see pages 73-79 for basic, not NMP-specific process description

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

OECD
in scope
2011

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 536 of 691

-------
Source Citation:

Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3828838

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Manufacture of paints, varnishes and similar coatings, printing ink

Process Description:	see pages 73-79 for basic, not NMP-specific process description

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

OECD
in scope
2011

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 537 of 691

-------
Source Citation:

Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3828838

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Manufacture of pharmaceuticals, medicinal chemicals and botanical

product

Process Description:	see pages 73-79 for basic, not NMP-specific process description

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

OECD
in scope
2011

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 538 of 691

-------
Source Citation:

Oecd,. 2017. Emission Scenario Document (ESD) on the use of textile dyes.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3828838

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Manufacture of soap and detergents, cleaning and polishing prepara-

tions, perfumes and toilet preparations (cosmetics)

Process Description:	see pages 73-79 for basic, not NMP-specific process description

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

OECD
in scope
2011

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High



1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 539 of 691

-------
Source Citation: White, D. L., Bardole, J. A.. 2004. Paint and finish removers.

Type of Data Source Facifity; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3859417

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Possible Physical Form:
Chemical Concentration:

Use

Paint stripper

>104 industries use finish removers. Finish removers are applied by
brushing, spraying, troweling, flowing, or soaking. Cleaning the sub-
strate may be by water rinse, wipe and let dry, or solvent rinse. Re-movers
may be neutral, basic, or acidic. The viscosity may be water thin, thick
enough to spray-on and cling, or a paste to be troweled on. liquid;
semipaste, water rinse finish remover

optimal = 40 to 50 mole percent ; Typical solution = 15 to 27.5wt
percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

From trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Medium

X 1

x 2
x 2
x 1

2
4
2

in scope

2006

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

addresses variability and uncertainty

Overall Quality Determination^

High

1.3

Continued on next page

Page 540 of 691

-------
— continued from previous page

Source Citation:	White, D. L.,Bardole, J. A.. 2004. Paint and finish removers.

Type of Data Source Facifity; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3859417

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 541 of 691

-------
Source Citation:

White, D. L.,Bardole, J. A..

2004. Paint and finish removers.

Type of Data Source

Facility; Reports for Data or

Information Other than Exposure or Release Data;

Hero ID

3859417



EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Processing

formulation of paint strippers

Finish removers may be manufactured in open or closed kettles. Closed
kettles are preferred because they prevent solvent loss and exposure to
personnel. To reduce emissions, condenser are often employed on vent
stacks. Mild steel or black iron kettles are used for neutral or basic
removers; stainless steel or reinforced polyethylene kettles are used for
acidic removers. The kettles are heated to aid dispersion of paraffin
waxes and mixing of other ingredients. Steel and polypropylene drums
are used for industrial removers.

There are about 51 paint remover manufacturers in the United States.

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 From trusted sources

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Medium

X

2

4

2006

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	High	X 1	1 addresses variability and uncertainty

Continued on next page

Page 542 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

White, D. L.,Bardole, J. A.. 2004. Paint and finish removers.
Facility; Reports for Data or Information Other than Exposure
3859417

or Release Data;



EVALUATION

Domain

Metric Rating MWF*

Score

Comments

Overall Quality Determination^ High

1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 543 of 691

-------
Source Citation:

Ashford, R. D.. 2001. Ashford's Dictionary of Industrial Chemicals N-methylpyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3860437

EXTRACTION



Parameter

Data

Life Cycle Stage:	Manufacture

Life Cycle Description (Subcategory of Use):	Manufacture

Process Description:	N-methylpyrrolidone is manufactured by combining ?-butyrolactone

with methylamine. NMP is used in chemical synthesis, petrochemical
extractions (aromatics, acetylene, butadiene), lubricating oil dearomati-
zation, paint removers, and coatings.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X

1

3

The data, data sources, and/or techniques used in the assess-
ment or report are not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium
High
Medium
N/A

XXX

1

2
2

2
2
4

N/A

UK

in scope
2001

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

X

1

4

Assessment or report does not document its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A





N/A

This metric is not applicable to this data type

Overall Quality Determination^

Unacceptable





4

Metric Mean Score: 2.1.

Continued on next page

Page 544 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

Ashford, R. D.. 2001. Ashford's Dictionary of Industrial ChemicalsN-methylpyrrolidone.
Facility; Reports for Data or Information Other than Exposure or Release Data;

3860437



EVALUATION

Domain

Metric Rating MWF* Score

Comments



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 545 of 691

-------
Source Citation: 2017. PubChem: l-Methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3860487

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Manufacture
Manufacturing

Large-scale production of NMP is predominantly carried out by reacting
gamma-butyrolacetone with an excess of pure or aqueous methyamine in
a high-pressure tube reactor (6-12 Mpa). The reaction is exothermic and
often run under adiabatic conditions with reactor temperatures in the
range of 250-400 deg C. The resulting product mixture is decompressed
and distilled. The NMP yield is normally more than 97 percent .
100 million to 500 million pounds/yr (2002)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

From trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Low

X 1

x 2
x 2
x 1

2
4

in scope
2002

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

limited discussion

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 546 of 691

-------
Source Citation:

2016. Agent name: N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3860491

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	Used as resin in microelectronics industrial paint stripping; lube oil

extraction; pesticides; coatings; adhesives dyes; pigments; polymers;
polyurethane foam cleanup

Process Description:	Lists the life cycle stages and chemical - physical properties.

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

NIH information

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

High

X

2

2

2016

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

Low

X

1

3

underlying methods, data sources, and assumptions are not













fully transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	N/A	N/A This metric is not applicable to this data type

Overall Quality Determination^	High	1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 547 of 691

-------
Source Citation:	2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3860493

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Petrochemical

Acetylene recovery from cracked gas, extraction of aromatics and buta-
diene, gas purification (removal of C02 and H2S)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope

oldest source listed from 1999

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

High

1.5

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 548 of 691

-------
Source Citation:	2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3860493

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Processing
plastics

Reaction medium for the production of high-temperature polymers such
as polyethersulfones, polyamideimides, and polyaramids

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope

oldest source listed from 1999

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

High

1.5

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 549 of 691

-------
Source Citation:	2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3860493

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Electronics

Cleaning agent for silicon wafers, photoresist stripper, auxiliary in
printed circuit board technology

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope

oldest source listed from 1999

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

High

1.5

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 550 of 691

-------
Source Citation:
Type of Data Source
Hero ID

2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Facility; Reports for Data or Information Other than Exposure or Release Data;

3860493

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Manufacture
Manufacture

Large-scale production of NMP is predominantly carried out by reacting
gamma-butyrolacetone with an excess of pure or aqueous methyamine in
a high-pressure tube reactor (6-12 Mpa). The reaction is exothermic and
often run under adiabatic conditions with reactor temperatures in the
range of 250-400 deg C. The resulting product mixture is decompressed
and distilled. The NMP yield is normally more than 97 percent . It can
also be produced by hydrogenation of N-hydroxymethyl-2-pyrrolidone or
reaction of acrylonitrile with methylamine in the presence of a peroxide
radical initiator.

12

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope

oldest source listed from 1999

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Continued on next page

Page 551 of 691

-------
— continued from previous page

Source Citation:	2017. Hazardous substances data bank: l-Methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3860493

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.5





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 552 of 691

-------
Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3969286

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):

Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

All

coating (paints, writing inks); cleaning products (paint strippers, glue
and grease removers, sealant removers); cosmetic and personal care prod-
ucts

Source is a high-level risk assessment for potential consumer exposure
to NMP in consumer products.

100 to 1000 tonnes (Australia)

5 percent (consumer prod limit in Europe); 0.3 percent (proposed new
consumer prod limit)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

High quality - journal articles, etc

Domain 2: Representative











Metric 2:

Geographic Scope

Medium

X 1

2

Australia

Metric 3:

Applicability

Low

x 2

6

non-occupational scenario that is similar to an occupational











scenario

Metric 4:

Temporal Representativeness

High

x 2

2

2016

Metric 5:

Sample Size

Medium

x 1

2

Range with uncertain statistics

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

Medium

x 1

2

Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty









Metric 7:

Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

Medium



1.8



Continued on next page

Page 553 of 691

-------
— continued from previous page

Source Citation:	Australian Government Department of, Health. 2016. Human health tier III assessment for l-methyl-2-pyrrolidinone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3969286

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 554 of 691

-------
Source Citation:

U.S, E. P. A.. 2017. Inert details: N-methyl-2-pyrrolidinone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3970073

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	pesticides

Process Description:	40 CFR 180.920 - indicates NMP is used in pesticides as a Solvent,

cosolvent

EVALUATION

Domain

Metric

Rating

MWF*

Score



Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

CFR





Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope
2004

This metric

is not applicable to this

data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

N/A



N/A

This metric

is not applicable to this

data type

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric

is not applicable to this

data type

Overall Quality Determination^

High



1.3







* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 555 of 691

-------
Source Citation: Echa,. 2017. Substance information: l-Methyl-2-pyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3970774

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

All

pH regulators and water treatment products and laboratory chemicals.
Substance information, including physical-chemical properties
This substance is manufactured and/or imported in the European Eco-
nomic Area in 10,000 to 100, 000 tonnes per year.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

ECHA substance database

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium
Medium
High

N/A

X 1

x 2
x 2

2
4
2

N/A

Europe

some of these uses were not identified by EPA
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

Medium

1.7

* MWF = Metric Weighting Factor

Page 556 of 691

-------
Source Citation:

Echa,. 2017. Uses as industrial sites: l-Methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Flero ID

3970775

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	Processing as intermediate; Formulation; Spray Application; Roll ap-

plication; Brush application; Dip /pour; Lab; tableting, compression,
extrusion, pelletization; Functional fluid; Lubrication at high energy con-
ditions; cleaning

Process Description:	List of life cycle stages and worker activities (high-level, such as transfer

or spraying)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Lligh

x 1

1

ECHA substance database

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

Lligh

High

N/A

X 1

x 2
x 2

2
2
2

N/A

Europe

all in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 557 of 691

-------
Source Citation:

Echa,. 2017. Uses by professional workers: l-Methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3970776

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	All (see above row)

Process Description:	Same information as 3970775

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

x 1

1

ECHA substance database

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

Europe

all in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 558 of 691

-------
Source Citation:	Echa,. 2017. Consumer uses: l-Methyl-2-pyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3970777

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Consumer Use
Printing

Indicates NMP is used in inks and toners by consumers

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

x 1

1

ECHA substance database

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

Europe
in scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 559 of 691

-------
Source Citation:	Niosh,. 2014. Health hazard evaluation report no. HHE-2011-0099-3211, evaluation of employee exposures during sea lamprey

pesticide application.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3974909

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Operating Days per Year and Batches per Day:
Possible Physical Form:

Chemical Concentration:

Use

Agricultural products

Employees manually applied pesticides into rivers to control sea lamprey
larvae. Bayluscide wettable powder and emulsifiable concentrate are
used. Technicians prepare equipment, then transport, mix, and apply
pesticides into the river. Technicians also analyze river water samples
in portable laboratories to measure pesticide concentrations throughout
a treatment period. Mix Bayluscide wettable powder into water before
pumping it into a maintenance application site
38 employees

wettable powder and emulsifiable concentrate

The liquid Bayluscide concentrate contains N-methyl-2-pyrrolidone

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

High

X 1

1

Information is from trusted sources (NIOSH HHE)

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

Agriculutral use is in scope

Metric 4:

Temporal Representativeness

High

x 2

2

2014

Metric 5:

Sample Size

N/A



N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x 1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Continued on next page

Page 560 of 691

-------
— continued from previous page

Source Citation:	Niosh,. 2014. Health hazard evaluation report no. HHE-2011-0099-3211, evaluation of employee exposures during sea lamprey

pesticide application.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3974909

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

High

X 1 1 The report addresses variability and uncertainty in the results.

Overall Quality Determination^

High

1.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 561 of 691

-------
Source Citation: Argonne National, Laboratory. 2015. Lithium-ion battery production and recycling materials issues.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3974981

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Batteries

NMP is used as a binder solvent in the assembly of lithium-ion batter-
ies. (I think binders are used to adhere the electrolytic cells to the
battery).

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

not from trusted sources, but do not seem flawed

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

in scope
2015

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Assessment or report provides results, but the underlying
methods, data sources, and assumptions are not fully trans-
parent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

no discussion

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 562 of 691

-------
Source Citation:	Nicnas,. 1997. Full public report: Polymer in byk-410.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978356

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Processing
polymer

NMP is the solvent in which the polymer is dispersed. The NMP-
polymer solution is added to coatings and serves to affect the rheological
properties of the coating

2,750 kg of NMP-polymer soln imported to Australia for use
45 percent NMP; 55 percent polymer

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information from industry contact,
source but no flaws identified.

Not standard trusted

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1

High	x 2

Low	x 2

Low	x 1

2	Australia

2	in scope
6	1997

3	Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Medium X 1	2 sources are not fully transparent, due to confidentiality of in-

dustry contact

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3 No discussion

Overall Quality Determination^

Medium

2.2



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 563 of 691

-------
Source Citation:	Nicnas,. 1997. Full public report: Polymer in byk-410.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978356

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Processing

coating /paint formulation

The mentioned NMP-polymer soln is added to coatings such that it
(NMP is 45 percent in NMP-polymer disp) is added to coatings at a
concentration of 0.1-3wt percent (corresponds to 0.45 to 1.35 percent
NMP)

2,750 kg of NMP-polymer soln imported to Australia for use
0.45 to 1.35 percent NMP in coating/paint

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information from industry contact,
source but no flaws identified.

Not standard trusted

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1

High	x 2

Low	x 2

Low	x 1

2	Australia

2	in scope
6	1997

3	Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium x 1

2

sources are not fully transparent, due to confidentiality of in-
dustry contact

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3

No discussion

Overall Quality Determination^

Medium

2.2



Continued on next page

Page 564 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 1997. Full public report: Polymer in byk-410.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3978356

EVALUATION

Domain

Metric

Rating

MWF* Score

Comments



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 565 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Formulation

polymeric adhesive for leather coating application

Adhesive will be decanted or pumped into a stainless steel mixing vessel,
mixed with other components such as pigment, defoamer, thickener and
water. Formulation is gravity fed or pumped into 200 litre drums or 20
litre pails and transported to the spray line (or customers).

Up to 40 tonnes/yr of polymer in formulation (polymer is 35 percent;
NMP is 5 percent)

5 percent

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information is from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	X	1	2	Australia

High	X	2	2	Adhesive formulation is in scope

Medium	x	2	4	2001

Low	X	1	3	Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x

1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x

1

2

limited discussion

Overall Quality Determination^

Medium



1.7





Continued on next

page





Page 566 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978357

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 567 of 691

-------
Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978357

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

polymeric adhesive for leather coating application

Formulation is pumped directly from drums or pails to spray unit. The
formulation will be applied by rotary spray application to untreated
leather on a conveyor line, and the treated leather will then be dried in
ovens through a drying tunnel prior to further treatment. Any overspray
is filtered and caught in a water curtain filtering system during the spray
application.

Up to 40 tonnes/yr of polymer in formulation (polymer is 35 percent ;
NMP os 5 percent )

EVALUATION







Domain

Metric

Rating

MWF* Score Comments

Domain 1: Reliability







Metric 1:

Methodology

High

X 1 1 Information is from trusted sources

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	X	1	2	Australia

High	X	2	2	Adhesive use is in scope

Medium	x	2	4	2001

Low	X	1	3	Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x

1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x

1

2

limited discussion

Overall Quality Determination^

Medium



1.7





Continued on next

page





Page 568 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 2001. Full public report: Polymer in primal binder u-51.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978357

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 569 of 691

-------
Source Citation: Nicnas,. 1998. Full public report: Copolymer in foraperle 321.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3978358

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Operating Days per Year and Batches per Day:
Chemical Concentration:

Use

Coating /additive in Papermaking

Polymer in NMP is imported to Australia in 50 kg to 1 tonne containers
for use in the paper and building industries. Polymer may be used as a
surface or internal treatment for paper and paper type products. The
product containing the notified polymer is transferred to a mixing tank,
which may have a holding capacity of up to 1,000 L. Product will then
be diluted significantly with water and applied to paper using rollers and
spray equipment. As internal paper treatment, the notifier states that
the product containing the notified polymer will be added to the paper
pulp following the washing and bleaching process, but before rolling and
cutting of the final paper product.

2500 kg polymer-NMP soln imported to Australia for use; assumed 2,000
kg/yr for paper
1 (assumed)

300 days/yr (assumed)

30 percent polymer & 10 to < 30 percent NMP in soln that is diluted
prior to use at paper mill

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information from industry contact,
source but no flaws identified.

Not standard trusted

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

Medium
High

Metric 4: Temporal Representativeness Low

X 1 2 Australia

X 2 2 This was not identified as a use by EPA, but no uses are ex-

cluded from scope. May be applicable to coating OES?

X 2 6 1998

Continued on next page

Page 570 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 1998. Full public report: Copolymer in foraperle 321.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978358

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 5: Sample Size

Low

X 1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

X 1

2

sources are not fully transparent, due to confidentiality of in-
dustry contact

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

No discussion

Overall Quality Determination^

Medium



2.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 571 of 691

-------
Source Citation:	Nicnas,. 1998. Full public report: Copolymer in foraperle 321.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978358

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Use

architectural (concrete) coating

product containing the notified polymer usually will be applied by brush
hence dermal and accidental ocular exposure may occur. The polymer
is used at 2.5 g.m-2.

2500 kg polymer-NMP soln imported to Australia for use; Assumed 500
kg/yr for coating

5 to 10 percent solution containing polymer & NMP in coating

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information from industry contact,
source but no flaws identified.

Not standard trusted

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium	x 1

High	x 2

Low	x 2

Low	x 1

2	Australia

2	in scope
6	1998

3	Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium x 1

2

sources are not fully transparent, due to confidentiality of in-
dustry contact

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low x 1

3

No discussion

Overall Quality Determination^

Medium

2.2



Continued on next page

Page 572 of 691

-------
— continued from previous page

Source Citation:	Nicnas,. 1998. Full public report: Copolymer in foraperle 321.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3978358

EVALUATION

Domain

Metric

Rating

MWF* Score

Comments



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 573 of 691

-------
Source Citation:

Osha,. 2006. OSHA permissible exposure limit and general information: n-methyl-2-pyrrolidinone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981001

EXTRACTION



Parameter

Data

Life Cycle Stage:	All

Life Cycle Description (Subcategory of Use):	All

Process Description:	Physical chemical properties; health effects; lab sampling method

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

High

X

1

1

OSHA

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

Medium

X

2

4

Information is not related to a life cycle stage, but is broadly













applicable

Metric 4:

Temporal Representativeness

High

X

2

2

2017

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

Medium

X

1

2

Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

N/A





N/A

This metric is not applicable to this data type

Overall Quality Determination^

High





1.4



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 574 of 691

-------
Source Citation: N-Methylpyrrolidone Procedures Group, Inc. 2006. N-methyl 2-pyrrolidone (NMP) considerations against use in cosmetics,

toiletries, and personal care products.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3981020

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Pharmaceutical

NMP was used in cosmetics, toiletries, and personal care products. The
EU banned this use and prohibited the general public from using non-
cosmetic products containing >=5 percent NMP.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

The data, data sources, and/or techniques used in the assess-

ment or report are not specified.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

Unacceptable

Pharmaceutical use is a non-TSCA use. Reported use is cos-

metics; therefore, out of scope.

Metric 4:

Temporal Representativeness

Medium

2006

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Low

data sources, and assumptions are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

Low

no discussion

Overall Quality Determination^

Unacceptable

Metric Mean Score: 2.8.

Continued on next page

Page 575 of 691

-------
— continued from previous page

Source Citation:	N-Methylpyrrolidone Procedures Group, Inc. 2006. N-methyl 2-pyrrolidone (NMP) considerations against use in cosmetics,

toiletries, and personal care products.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3981020

EVALUATION

Domain

Metric

Rating

MWF* Score

Comments



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

I If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 576 of 691

-------
Source Citation:

Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981028

EXTRACTION



Parameter

Data

Life Cycle Stage:	Manufacture

Life Cycle Description (Subcategory of Use):	manufacturing

Process Description:	produces high-purity, high-grade NMP from maleic anhydride in an in-

tegrated production process.

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 577 of 691

-------
Source Citation: Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3981028

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Metal finishing; Electronics

Electronics: Wax, flux removal. Burr removal. Electronic parts clean-
ing. Semiconductor parts cleaning. Solvent for lithium battery manu-
facturing. Semiconductor photo-resist thinner. Color filter photo-resist
thinner

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 578 of 691

-------
Source Citation:

Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981028

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Automotive care

Process Description:	Mold cleaning. Metal (parts) cleaning.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 579 of 691

-------
Source Citation:

Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981028

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	Petrochemical

Process Description:	Extract agent (acetylene, BTX, butadiene).

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 580 of 691

-------
Source Citation:

Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981028

EXTRACTION



Parameter

Data

Life Cycle Stage:	Processing

Life Cycle Description (Subcategory of Use):	intermediate

Process Description:	Reaction solvents (PPS, polyimide, etc.)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 581 of 691

-------
Source Citation:

Mitsubishi, Chemical. 2017. NMP/N-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981028

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	cleaning

Process Description:	Plastic lens manufacturing equipment cleaning. Equipment washing.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

High

N/A

X 1

x 2
x 2

2
2
2

N/A

NMP MFG site is in Japan

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^	High	1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 582 of 691

-------
Source Citation: Johnson Matthey Process, Technologies. 2017. N-methyl-2-pyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3981029

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Manufacture
Manufacturing

Contains PFD and reaction sequences. Our technology generates high-
quality NMP by reacting gamma-butyrolactone (GBL) and monomethy-
lamine (MMA), which are products of our butanediol and methylamines
processes, respectively. Additional process description available.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High

N/A

X 1

x 2
x 2

3
2
2

N/A

Unknown - could be US based or other countries

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Data sources not transparent

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

Medium

1.7

* MWF = Metric Weighting Factor

Page 583 of 691

-------
Source Citation:

Bpi,. 2017. NMP free water borne polyurethane dispersions.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981030

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Coatings

Process Description: N-Methyl-2-Pyrrolidone (NMP) is the most common co-solvent used in

the manufacture of waterborne polyurethane dispersions. The unique
properties of NMP aid in both the processing of the polyurethane dis-
persions as well as the Aim formation of the applied polyurethane coating.
In addition, the NMP can help with substrate wetting, freeze/thaw sta-
bility, and adhesion to some substrates.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High

N/A

XXX

2
2

3
2
2

N/A

Unknown - could be US based or other countries

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ Medium 1.7

* MWF = Metric Weighting Factor

Page 584 of 691

-------
Source Citation: Spin,. 2017. SPIN substances in preparations in nordic countriesl-methyl-2-pyrrolidon.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3981132

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

All
All

Lists applicable Nordic NAICS equivalents. List of uses in nordic coun-
tries, in generic terms (i.e., degreasers, paints, laquers and varnishes,
etc.).

lists nordic PV for each use

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

x 1

Nordic substance database

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium

High

N/A

X 1

x 2
x 2

2
2
2

N/A

Norway, Finland, other OECD member countries

in scope

2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ High 1.4

* MWF = Metric Weighting Factor

Page 585 of 691

-------
Source Citation:

European Chemicals, Agency. 2016. l-methyl-2-pyrrolidone brief profile.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3981148

EXTRACTION



Parameter

Data

Life Cycle Stage:	Manufacture

Life Cycle Description (Subcategory of Use):	Manufacture or import

Total Annual U.S. Volume (and percent of PV):	10,000-100,000 tonnes/yr (EU)

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

not from trusted sources, but do not seem flawed

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Low
High
High
Low

X 1

x 2
x 2
x 1

3
2

2

3

Europe
in scope
2016

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

3

Assessment or report provides results, but the underlying
methods, data sources, and assumptions are not fully trans-
parent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

Medium



2.0



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 586 of 691

-------
Source Citation:

Basf,. 1990. Technical information: N-methylpyrrolidone handling and storage.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3982070

EXTRACTION

Parameter

Data

Life Cycle Stage: All

Life Cycle Description (Subcategory of Use): All

Process Description: Physical chemical properties; lab analysis methods; biodegradability and

aquatic toxicity; lists proper storage and equipment that should be used
for NMP. NMP can be handled in carbon steel, stainless steel or nickel
equipment. Aluminum is suitable for NMP service at ambient tempera-
tures, only. Storage at ambient temperatures will not affect NMP. Cool
storage conditions and light paint on aboveground tanks decrease evap-
orative losses.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:

Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
Medium

Low
N/A

X 1

x 2
x 2

N/A

Information is not related to a life cycle stage, but is broadly
applicable

1990

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

Low

2.3

Continued on next page

Page 587 of 691

-------
— continued from previous page

Source Citation:	Basf,. 1990. Technical information: N-methylpyrrolidone handling and storage.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982070

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 588 of 691

-------
Source Citation:	Turi,. 1996. N-methyl pyrrolidone: Chemical profile.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3982071

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Manufacture
Manufacturing

NMP is manufactured mainly by condensing butyrolactone with
methylamine. It may also be made by high pressure synthesis from
acety-lene and formaldehyde. Separation of the water and NMP is
generally achieved by distillation,
at least 99.8

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

data or techniques that are high quality

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
N/A

X 1

x 2
x 2

1

2
6

N/A

US

in scope

1996

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 589 of 691

-------
Source Citation:	Turi,. 1996. N-methyl pyrrolidone: Chemical profile.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3982071

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

Paint stripper

paint stripping accounts for only 10-15 percent
10-15 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

data or techniques that are high quality

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
Low

X 1

x 2
x 2
x 1

1

2
6

3

US

in scope

1996

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

limited discussion

Overall Quality Determination^

Medium



1.8



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 590 of 691

-------
Source Citation:	U.S, E. P. A.. 1998. Cleaner technologies substitutes assessment for professional fabricare processes: Appendix F: Chemical

volume estimates: Screen printing CTSA.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982072

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Batch Size:

Operating Days per Year and Batches per Day:
Site Daily Throughput:

Possible Physical Form:

Chemical Concentration:

Use

screen printing - cleaning of screens
38,000 gal NMP used in screen cleaning/yr
20,000 screen printing facilities

screen size and additional parameters to determine chemical cleaning
throughput in Table F-l
assumed 252 days/yr

57 percent of facilities clean one to ten screens, or an average of 5.5 a

day.

liquid

35 percent NMP in solution used to clean screens

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	High	x 1	1 US EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1998

Metric 5:

Sample Size

Low

X

1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 report clearly documents its data sources, assessment methods,

results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium x 1	2 limited discussion

Continued on next page

Page 591 of 691

-------
— continued from previous page

Source Citation:	U.S, E. P. A.. 1998. Cleaner technologies substitutes assessment for professional fabricare processes: Appendix F: Chemical

volume estimates: Screen printing CTSA.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982072

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



Medium 1.8





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 592 of 691

-------
Source Citation:

University of, Minnesota. 2007. Safter stripping and cleaning chemicals for coatings & polymers.

Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID

3982073

EXTRACTION



Parameter

Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Paint stripper

Process Description:	alternative stripping methods include: abrasive blasting, water blasting,

scraping, sanding, tumbling, burn off and cold shock

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

not from trusted sources; however, associated information does
not indicate flaws or quality issues

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope
2007

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A



N/A

This metric is not applicable to this data type

Overall Quality Determination^

High



1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 593 of 691

-------
Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982074

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Possible Physical Form:

Use

immersion degreasing

Degreasing with NMP entails the immersing of an oil coated metal part
into a heated bath of NMP, where the oil is solubilized. Upon removal
from the cleaning bath, the part is immersed into a second heated bath,
to remove the oil contaminated NMP from the metal surface. The sec-
ond, or rinse bath, can be filled with either NMP or water. Drying the
rinse liquid from the metal part is required.

10 complete cleaning cycles/hr; 5.0 lbs of parts cleaned per cycle
liquid

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium X 1	2 not from trusted sources, but do not seem flawed

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

Cleaning is included in scope

Metric 4:

Temporal Representativeness

Low

X

2

6

1993

Metric 5:

Sample Size

Low

X

1

3

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	Low	X 1	3 Assessment or report provides results, but the underlying

methods, data sources, and assumptions are not fully trans-
parent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	x 1	3 no discussion

Continued on next page

Page 594 of 691

-------
— continued from previous page

Source Citation:	Basf,. 1993. Modification of a vapor degreasing machine for immersion cleaning use N-methylpyrrolidone.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982074

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



Medium 2.2





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 595 of 691

-------
Source Citation:	Erg,. 2000. Preferred and alternative methods for estimating air emissions from paint and ink manufacturing facilities.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982076

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Processing

Paint and ink formulation

Paint and ink manufacturing can be classified as a batch process and gen-
erally involves the blending/mixing of resins, pigments, solvents, and ad-
ditives. Traditional paint and ink manufacturing consists of four major
steps: Preassembly and premix; Pigment grinding /milling /dispersing;
Product finishing/blending; and Product filling/packaging (Fisher et al.,
1993).

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

From trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

1

2
4

N/A

US

in scope
2000

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

well characterized

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 596 of 691

-------
Source Citation:

Larranaga, M. D., Lewis, R.

J., Lewis, R. A.. 2016. Hawley's Condensed Chemical DictionaryN-methyl-2-pyrrolidone.

Type of Data Source

Facility; Reports for Data or

Information Other than Exposure or Release Data;

Hero ID

3982124

EXTRACTION

Parameter

Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Solvent for resins, acetylene, etc., pigment dispersant, petroleum pro-

cessing, spinning agent for polyvinyl chloride, microelectronics industry
plastic solvent applications, intermediate.

Process Description: lists physical chemical properties and uses of NMP

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

Hawley's Condensed Chemical Dictionary

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

all uses are in scope

Metric 4:

Temporal Representativeness

High

2016

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

Low

underlying data source are not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ High 1.3

* MWF = Metric Weighting Factor

Page 597 of 691

-------
Source Citation: Technikon, L. L. C.. 2001. Core box cleaner study: Evaporative emission study of specialty systems' solvent FC-47-G1.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3982183

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Chemical Concentration:

Use

cleaning of casts /molds and hoppers in foundry applications
Cleaning to remove sand from casting and molding equipment. Solvent
is sprayed onto casts /molds at 80-90 psi, rate of 0.08-0.27 gal/min.
Solvent allowed to soak for 20 mins, then removed when the next part
is molded and removed. Solvent sprayed on hoppers, soaked for 2-13
hours, chipped off.

Molds = 0.5-1.2 gal of solvent /mold /day; Hoppers = 4.0-5.4 gal/
hopper/day

NMP at unknown concentration

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

High quality techniques

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Medium

X 1

x 2
x 2
x 1

2
4
2

in scope
2001

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

well characterized

Overall Quality Determination^

High

1.3

Continued on next page

Page 598 of 691

-------
— continued from previous page

Source Citation:	Technikon, L. L. C.. 2001. Core box cleaner study: Evaporative emission study of specialty systems' solvent FC-47-G1.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982183

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 599 of 691

-------
Source Citation:	Oehha,. 2007. Occupational health hazard risk assessment project for California: Identification of chemicals of concern,

possible risk assessment methods, and examples of health protective occupational air concentrations.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982225

EXTRACTION

Parameter	Data

Life Cycle Stage:	Manufacture

Life Cycle Description (Subcategory of Use):	Manufacturing

Total Annual U.S. Volume (and percent of PV):	>100M-500M

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

data or techniques that are high quality

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
Low

X 1

x 2
x 2
x 1

1

2
4

3

US

in scope
2002

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

clearly documents its data sources

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

1

addresses variability and uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 600 of 691

-------
Source Citation:	Ec,. 2004. Effectiveness of vapour retardants in reducing risks to human heafth from paint strippers containing

dichloromethane.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3982358

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Paint stripper

Chemical Concentration:	5-20 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

trusted sources

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

Medium
High
Medium
Medium

X 1

x 2
x 2
x 1

2
2
4
2

Belgium
in scope
2004

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Medium

x 1

2

Data sources are generally described but not fully transparent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

no discussion

Overall Quality Determination^

Medium



1.8



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 601 of 691

-------
Source Citation: Erm,. 2017. Life cycle assessment of used oil management.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3982372

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Use

Petrochemical

NMP can be used for re-refining of used oil to produce lube base oil. Some
process information on pg 70, but confidentiality claims make it difficult
to know the process used.

0.06 kg NMP/1 kg of processed used oil

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Low

X
X
X
X

2
2
1

in scope
2017

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

Assessment or report provides results, but the underlying
methods, data sources, and assumptions are not fully trans-
parent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

well characterized

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 602 of 691

-------
Source Citation:	U.S, E. P. A.. 2013. Fact sheet: N-Methylpyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986610

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

Paint and Coating Removal

Indicates that Gloves made of butyl rubber or laminated polyethylene/
EVOH are resistant to NMP. Does not list customary PPE.

9 percent of 184 million lbs/yr

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X 1

3

The data, data sources, and/or techniques used in the assess-
ment or report are not specified.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
Low

X 1

x 2
x 2
x 1

1

2
6

3

US

In scope
No date

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Unacceptable

x 1

4

Assessment or report does not document its data sources, as-
sessment methods, and assumptions.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

The report does not address variability or uncertainty.

Overall Quality Determination^

Unacceptable



4

Metric Mean Score: 2.4.







Continued on next

page





Page 603 of 691

-------
— continued from previous page

Source Citation:

U.S, E. P. A.. 2013. Fact sheet: N-Methylpyrrolidone (NMP).



Type of Data Source

Facility; Reports for Data or Information Other than Exposure or Release Data;



Hero ID

3986610



EVALUATION





Domain

Metric Rating MWF* Score

Comments



** Consistent with our Application of Systematic Review in TSCARisk Evaluations document, if a metric for a data source receives a score of Unacceptable (score = 4),
EPA will determine the study to be unacceptable. In this case, one of the metrics were rated as unacceptable. As such, the study is considered unacceptable and the
score is presented solely to increase transparency.

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:

High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 604 of 691

-------
Source Citation:	McCormick, L. 2017. Comment submitted by Lindsay McCormick, Chemicals and Health Project Manager on behalf of

Environmental Defense Fund (EDF). EDF.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986675

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Chemical Concentration:

Use
coating
<5 percent

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From environmental organization. No bias /errors evident with
respect to this information.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

Limited information on concentration variability

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 605 of 691

-------
Source Citation: McCormick, L. 2017. Comment submitted by Lindsay McCormick, Chemicals and Health Project Manager on behalf of

Environmental Defense Fund (EDF). EDF.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986675

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): paint stripper /removers

Chemical Concentration: 25-50 percent ; 10-15 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From environmental organization. No bias /errors evident with
respect to this information.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

2
2
2

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^ High 1.3

* MWF = Metric Weighting Factor

Page 606 of 691

-------
Source Citation: Holmes, L. 2017. Comment submitted by Laurie Holmes, Senior Director, Environmental Policy, Motor & Equipment Manu-

facturers Association (MEMA). Motor & Equipment Manufacturers Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986676

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Adhesive

NMP is used during the motor vehicle component manufacturing process
as an adhesive (added as a viscosity aid). It may also be used in inks,
varnishes, paint thinners, paint primers, paint removers, paste, lacquer,
and solvents. When NMP is used as a viscosity aid in an adhesive in
automotive applications, the chemical is cured and there is no solvent
remaining.

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X
X
X

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ High 1.1

Continued on next page

Page 607 of 691

-------
— continued from previous page

Source Citation:	Holmes, L. 2017. Comment submitted by Laurie Holmes, Senior Director, Environmental Policy, Motor & Equipment Manu-

facturers Association (MEMA). Motor & Equipment Manufacturers Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986676

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 608 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Thomas, T. 2017. Comment submitted by Todd Thomas, ELANTAS PDG, Inc. (EPDG).
Facility; Reports for Data or Information Other than Exposure or Release Data;

3986789

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Processing /Use

Polymers and Electronics (wires)

Functional Uses: Reaction medium for the manufacture of high tem-
perature polymers; Solvent and/or diluent for synthesis of wire enamels
and related intermediates; Dye solutions for use in wire coatings; Pro-
cess vessel cleaning solvent; Limited use as an industrial cleaning solvent
strictly in the wire coating industry; Limited use as a cleaning solvent in
regulated metal parts washer applications; Limited use as a flexibilizer for
B-Stage coatings (i.e., dried but not cured)

EPDG used the following weights (in pounds) by year going back to
2014:- 2014 1,606,040- 2015 1,481,993- 2016 1,253,048

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	N/A

N/A This metric is not applicable to this data type

Continued on next page

Page 609 of 691

-------
— continued from previous page

Source Citation:	Thomas, T. 2017. Comment submitted by Todd Thomas, ELANTAS PDG, Inc. (EPDG).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986789

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	High	1.1

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 610 of 691

-------
Source Citation: Brown, T; Bennett, S. 2017. Comment submitted by Timothy Brown, Regulatory Counsel and Steven Bennett, Vice President

of Scientific Affairs, Consumer Specialty Products Association (CSPA). Consumer Specialty Products Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986792

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): metal finishing

Process Description: CSPA notes industrial/commercial use of N-methylpyrrilidone as pene-

trant used for determination of metal fatigue for turbines, bridges, and
other critical uses, for inspections of metal fatigue, welding cracks, etc.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^ High 1.1

* MWF = Metric Weighting Factor

Page 611 of 691

-------
Source Citation: MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986795

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Total Annual U.S. Volume (and percent of PV):

Number of Sites:

Manufacture
Manufacture / import

The CDR submissions data for 2011 through 2015, inclusive, report an
average annual U.S. production (domestic manufacture plus imports)
of 170 million pounds per year, with a range from 160 to 187 million
pounds. During this same time period, imports from China rose sharply
to four million pounds, more than 2 percent of total U.S. production,
four companies producing NMP in the United States according to CDR
and other data: Ashland (in Texas City, TX), BASF (Geismar, LA),
Eastman (Fieldale, VA), Lyondell (Channelview, TX)

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From environmental organization. No bias/errors evident with

respect to this information.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2017

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness N/A N/A This metric is not applicable to this data type

Continued on next page

Page 612 of 691

-------
— continued from previous page

Source Citation:	MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986795

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.1





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 613 of 691

-------
Source Citation:	MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986795

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Chemical Concentration:

Use

paints, coatings, adhesives

5-7 percent ; 0.25-0.5 percent ; <4 percent ; 8-12 percent ; 1-2.5 percent ;
0.3-1 percent ; 5-10 percent ; 1.6 percent ; 2.5-10 percent ; 1-2.5 percent ;
1-2.5 percent ; 0.1-1 percent ; 0.1-1 percent ; 0.1-1 percent ; 0.1-1 percent
; 1-3 percent ; 1-2.5 percent ; 2.5-10 percent ; 1-3 percent

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

From environmental organization. No bias /errors evident with
respect to this information.

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

2017

Metric 5: Sample Size

Medium

X

1

2

Range with uncertain statistics

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Information is from the source

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

Medium

X

1

2

Limited information on concentration variability

Overall Quality Determination^	High	1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 614 of 691

-------
Source Citation:	MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986795

EXTRACTION

Parameter	Data

Life Cycle Stage:	Use

Life Cycle Description (Subcategory of Use):	Pesticides

Process Description:	Dog flea and tick remover

Chemical Concentration:	30-47 percent

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

From environmental organization. No bias /errors evident with











respect to this information.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

Medium

x 2

4

Pesticide not in scope of TSCA; however, information is appli-











cable to formulation

Metric 4:

Temporal Representativeness

High

x 2

2

2017

Metric 5:

Sample Size

Medium

x 1

2

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 Limited information on concentration variability

Overall Quality Determination^

High

1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 615 of 691

-------
Source Citation: MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986795

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): cleaners

Chemical Concentration: 100 percent ; 100 percent ; 5-10 percent ; <1 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From environmental organization. No bias /errors evident with
respect to this information.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

2
2
2

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^ High 1.3

* MWF = Metric Weighting Factor

Page 616 of 691

-------
Source Citation: MacRoy, P. 2017. Comment submitted by Patrick MacRoy on behalf of Environmental Health Strategy Center et al.. Envi-

ronmental Health Strategy Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986795

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): paint stripper /removers

Chemical Concentration: 50 percent ; 10-20 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From environmental organization. No bias /errors evident with
respect to this information.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

2
2
2

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^ High 1.3

* MWF = Metric Weighting Factor

Page 617 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

electronics - Photoresist Stripping

NMP is used as a solvent in circuit board manufacturing in photoresist
stripping. Some facilities report that photoresist stripping occurs in
batches; others report continuous processing. The NMP used in the
process is up to 100 percent concentration, is in liquid or liquid spray
form, and is heated up to 85 "F. Facilities report that storage can be in
55-gallon drums, totes, or one to five gallon bottles,
up to 100 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^

High

1.3

Continued on next page

Page 618 of 691

-------
— continued from previous page

Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 619 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

electronics - Soldermask Stripping

Liquid NMP (up to 99.9 percent concentration) is used to remove solder
mask in circuit boards. Solder mask stripping typically occurs as a
batched process in an open topped tank equipped with ventilation. The
NMP used is reportedly at ambient temperature or heated up to 180"F.
The NMP used in the process is typically stored in 55-gallon drums or
one to five gallon containers,
up to 99.9 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^

High

1.3

Continued on next page

Page 620 of 691

-------
— continued from previous page

Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 621 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
NMP is a carrier solvent used to uniformly apply a polymer to man-
ufacture an industrial membrane. The polymer and NMP are mixed
as batches in a steel tank with controlled releases and local ventilation,
followed by application of the polymer solution and extraction of the
NMP in a water bath. The NMP used in the process is greater than 50
percent concentration in liquid form and is heated. NMP can be stored
in tanks, bulk containers, totes, or drums,
greater than 50 percent

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2017

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Medium X 1 2 Limited information on concentration variability

Continued on next page

Page 622 of 691

-------
— continued from previous page

Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 623 of 691

-------
Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Fertilizer application

NMP is a solvent used in the production of a fertilizer additive that
prevents the volatilization of urea (as ammonia). As further detailed
below, fertilizer additive products that may contain NMP are controlled
and finished fertilizers that have such small amounts of NMP, it would be
an unnecessary expenditure of EPA"s time to evaluate them for further
regulatory restriction.

15-45 percent in additive; 0.1 percent in final product

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium X 1	2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope	High	x 1	1

Applicability	High	x 2	2

Temporal Representativeness High	x 2	2

Sample Size	Medium	x 1	2

US

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	x 1	1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium X 1	2 Limited information on concentration variability

Overall Quality Determination^	High	1.3

Continued on next page

Page 624 of 691

-------
— continued from previous page

Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 625 of 691

-------
Source Citation: Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986796

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Processing

Formulation and distribution

NMP is often handled by distributors that blend and package products
containing NMP, such as industrial paint stripper formulations or indus-
trial surface cleaning blends. On site, NMP is stored in tanks, totes,
drums, or tank trucks. Within the distribution facility, NMP is pro-
cessed in mixers and tanks within closed and controlled release systems.
Processing is typically batched. The NMP is in the liquid form at am-
bient or increased temperature.

5-100 percent

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2017

Metric 5:

Sample Size

Medium

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Medium X 1 2 Limited information on concentration variability

Continued on next page

Page 626 of 691

-------
— continued from previous page

Source Citation:	Roberts, KM. 2017. Comment submitted by Kathleen M. Roberts, N-Methylpyrrolidone (NMP) Producers Group Manager,

NMP Producers Group, Inc.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986796

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 627 of 691

-------
Source Citation:	Gerber, JM. 2017. Comment submitted by Jonathan M. Gerber, Advanced Regulatory Specialist, 3M Medical Department,

Toxicology & Compliance Solutions 3M Center, Part 2. 3M Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986797

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Chemical Concentration:

Use

Paints, coatings, adhesives

0.5 percent ; 5-15 percent ; <5 percent ; <1.5 percent ; <0.5 percent ;
<14 percent ; <1 percent ; 1-5 percent ; <0.5 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

1

2
2
2

US

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

Limited information on concentration variability

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 628 of 691

-------
Source Citation:	Gerber, JM. 2017. Comment submitted by Jonathan M. Gerber, Advanced Regulatory Specialist, 3M Medical Department,

Toxicology & Compliance Solutions 3M Center, Part 2. 3M Center.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986797

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Chemical Concentration:

Use

Printing Inks
5-10 percent

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium X 1	2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2: Geographic Scope

High

X

1

1

US

Metric 3: Applicability

High

X

2

2

In scope

Metric 4: Temporal Representativeness

High

X

2

2

2017

Metric 5: Sample Size

Medium

X

1

2

Range with uncertain statistics

Domain 3: Accessibility/Clarity











Metric 6: Metadata Completeness

High

X

1

1

Information is from the source

Domain 4: Variability and Uncertainty











Metric 7: Metadata Completeness

Medium

X

1

2

Limited information on concentration variability

Overall Quality Determination^	High	1.3

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 629 of 691

-------
Source Citation:	Riegle, L. 2017. Comment submitted by Leslie Riegle, Director of Environmental Policy Aerospace Industries Association

(AIA), Part 3. Aerospace Industries Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986798

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Paint stripper

Specific aerospace industrial uses include but may not be limited to:
solvents for both cleaning and removal of coatings (in electronics as
well as for use with specific coatings and applications); as a constituent
in adhesives, release agents, inks, coatings (including topcoats, primers
and specialty coatings) surface pretreatments; as well as a sealant for
sensitive military aircraft applications.

15-35 percent

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

1

2
2
2

US

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

Limited information on concentration variability

Overall Quality Determination^

High



1.3



Continued on next page

Page 630 of 691

-------
— continued from previous page

Source Citation:	Riegle, L. 2017. Comment submitted by Leslie Riegle, Director of Environmental Policy Aerospace Industries Association

(AIA), Part 3. Aerospace Industries Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986798

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 631 of 691

-------
Source Citation: Anonymous. 2017. Anonymous public comment, Part 7.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID 3986799

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
NMP is imported as a dispersant liquid for polymer particles. NMP
solution is applied by gravure to form a polymer film. NMP is dried and
captured for recycle/reuse.

<1 metric ton; max. of <20 metric ton/yr
6 companies in the US that use NMP this way

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Low

X 1

Anonymous comment - data, data sources, and/or techniques
used in the assessment or report are not specified

Domain 2: Representative

Metric 2: Geographic Scope

Metric 3: Applicability

Metric 4: Temporal Representativeness

Metric 5: Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

Page 632 of 691

-------
Source Citation:	Davis, R. 2017. Comment submitted by Raleigh Davis, Assistant Director, Environmental Health and Safety, American

Coatings Association (ACA), Part 2. American Coatings Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986800

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Paints, coatings, adhesives

NMP is used as a coalescing aid in antistatic applications. NMP is
used in wax dispersions technology, allowing coatings systems to im-prove
the dispersions of pigments. NMP is used as a rheology additive to control
the viscosity of urethane coatings in the process of making aque-ous
dispersions. NMP is capable of dissolving polymers that are difficult to
process.

0.5 percent ; <1 percent ; 5-15 percent
<0.1 percent ; 1-5 percent ; 45-60 percent
0.1-1 percent ; <2 percent ; <1.5 percent ;

; 1-5 percent ; 0.1-1 percent ; 1-5 percent
<0.5 percent ; <14 percent ; 1-2 percent ;

; 0.2-2 percent

1-5 percent ; 0.1-1 percent ;
5-10 percent ; 1-5 percent ;
<0.2 percent ; 10-50 percent
; <5 percent ; <1.5 percent ;
0.8-2.1 percent ; 2-3 percent

EVALUATION











Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability











Metric 1:

Methodology

Medium

X 1

2

Trade association poll of manufacturers. No bias /errors evi-











dent.

Domain 2: Representative











Metric 2:

Geographic Scope

High

X 1

1

US

Metric 3:

Applicability

High

x 2

2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2

2017

Metric 5:

Sample Size

Medium

x 1

2

Range with uncertain statistics

Domain 3: Accessibility/Clarity









Metric 6:

Metadata Completeness

High

x 1

1

Information is from the source

Continued on next page

Page 633 of 691

-------
— continued from previous page

Source Citation:	Davis, R. 2017. Comment submitted by Raleigh Davis, Assistant Director, Environmental Health and Safety, American

Coatings Association (ACA), Part 2. American Coatings Association.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986800

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Medium X 1	2 Limited information on concentration variability

Overall Quality Determination^

High

1.3



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 634 of 691

-------
Source Citation: Isaacs, D. 2017. Comment submitted by David Isaacs, Semiconductor Industry Association (SIA).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986801

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics - semiconductor manufacturing

The semiconductor industry uses NMP in manufacturing for three main
purposes:l. Dedicated solvent in certain photolithography formulations,
including photoresists, Bottom Anti-Reflective Coatings (BARC) and
polyimides2. Solvent pre-wet of wafers prior to application of spin on
polymer3. Component of photoresist stripper formulations.

No NMP is present in the final polyimide film.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

Trade association poll of manufacturers. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 635 of 691

-------
Source Citation: Rudnick, M. 2017. Comment submitted by Michelle Rudnick, Senior Manager Regulatory Affairs, CRC Industries, Inc., Part

2. CRC.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986802

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Chemical Concentration:

Use

paint stripper /removers

CRC uses NMP in two gasket remover aerosol products and one graffiti
remover aerosol product. To use the product, we recommend that the
surface be coated with the graffiti remover product and allowed to sit
for 5 minutes. The paint can then be wiped or scraped off.

3 oz (1/4 of a can) for the average gasket
<=20 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^

High

1.3

Continued on next page

Page 636 of 691

-------
— continued from previous page

Source Citation:

Type of Data Source
Hero ID

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Rudnick, M. 2017. Comment submitted by Michelle Rudnick, Senior Manager Regulatory Affairs, CRC Industries, Inc., Part
2. CRC.

Facility; Reports for Data or Information Other than Exposure or Release Data;

3986802

Page 637 of 691

-------
Source Citation: National Electrical Manufacturers Association. 2017. Comment submitted by National Electrical Manufacturers Association

(NEMA).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986803

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics - magnet wires

The magnet wire industry has long utilized NMP as a solvent/diluent in
high-performance magnet wire enamels, thinners, and cleaners. Specifi-
cally, magnet wire plays a critical role in three areas of energy transfor-
mation through its use today in transformers, motors and generators. In
the magnet wire industrial process a copper or aluminum wire is routed
through an applicator of solvent-based enamel coating. NMP does not
react with the other ingredients in this coating, but is simply mixed in
to facilitate the smooth application of the enamel.

80-85 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2017

Metric 5:

Sample Size

Medium

x 1

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Medium X 1 2 Limited information on concentration variability

Continued on next page

Page 638 of 691

-------
— continued from previous page

Source Citation:	National Electrical Manufacturers Association. 2017. Comment submitted by National Electrical Manufacturers Association

(NEMA).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986803

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 639 of 691

-------
Source Citation: Haas, G. 2017. Comment submitted by Gerhard Haas, Vice President, Research & Development, Technical Service, Purchasing,

Jowat Corporation, Part 2. Jowat Corporation.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986804

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Use
coating

Primer which promotes adhesion. The NMP containing primer is applied
with a slot die and then dried in a heat tunnel.

imported 850001bs of the primer last year which contained a total of
4250 lbs of NMP
<5 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

Page 640 of 691

-------
Source Citation: Turner, S. L., McCrillis, R. C.. 2017. Evaluation of alternative chemical strippers on wood furniture coatings.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 3986887

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Chemical Concentration:

Use

Paint stripper

Solvent strippers work solely by dissolving the coating film. Their dis-
solving mechanism causes them to become rapidly saturated with dis-
solved coating.

1.74 to 3.23E-04 m3 of stripper per m2 of substrate surface
50-75 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

The assessment or report uses high quality data and/or tech-
niques that are not from trusted sources; however, Associated
information does not indicate flaws or quality issues.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
Low

X 1

x 2
x 2
x 1

2
6

In scope
No date

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

Low

x 1

Assessment or report provides results, but the underlying
methods, data sources, and assumptions are not fully trans-
parent.

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

The report does not address variability or uncertainty.

Overall Quality Determination^

Medium

2.2

Continued on next page

Page 641 of 691

-------
— continued from previous page

Source Citation:	Turner, S. L.,McCrillis, R. C.. 2017. Evaluation of alternative chemical strippers on wood furniture coatings.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	3986887

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 642 of 691

-------
Source Citation: Us, E. P. A.. 1988. PRODUCTION EXPOSURE PROFILE N-METHYLPYRROLIDONE.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 4214097

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Total Annual U.S. Volume (and percent of PV):

Number of Sites:

Manufacture
Domestic manufacturing

BASF production in 1987 estimate of 15-25 million lbs/yr, no known
volume for second producer, no imports
2

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Manufacturing in scope

Metric 4:

Temporal Representativeness

Low

1988

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

Data sources are included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness N/A

N/A This metric is not applicable to this data type

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 643 of 691

-------
Source Citation:	Us, E. P. A.. 1988. PRODUCTION EXPOSURE PROFILE N-METHYLPYRROLIDONE.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214097

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Chemical Concentration:

Processing
Formulation

Processing NMP into paint stripper formulations.
6

<=49

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

1

EPA

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Low
N/A

X 1

x 2
x 2

1

2
6

N/A

US

Manufacturing in scope
1988

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Data sources are included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

2

Limited information on concentration variability

Overall Quality Determination^

High



1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 644 of 691

-------
Source Citation: E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 4214100

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Number of Sites:

Site Daily Throughput:

Processing

Processing as a reactant

Several industrial applications including dissolving organic polymers and
monomers for manufacture of synthetic fibers, resins, composite mate-
rials and film coatings.

55 million lbs/yr in 1989
1

Daily use unknown. Annual use of 1.6 million lbs/yr in 1989

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Processing in scope

Metric 4:

Temporal Representativeness

Low

1989

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Data is from source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness N/A N/A This metric is not applicable to this data type

Overall Quality Determination^ Medium 1.7

Continued on next page

Page 645 of 691

-------
— continued from previous page

Source Citation:	E. I. Dupont De Nemours,Co,. 1990. LETTER FROM E I DUPONT DE NEMOURS & COMPANY TO USEPA SUBMIT-

TING COMMENTS CONCERNING THE PROPOSED TEST RULE ON N-METHYLPYRROLIDONE WITH ATTACH-
MENT.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214100

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 646 of 691

-------
Source Citation: Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 4214135

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Manufacture
Domestic manufacturing

Continuous reaction process forms NMP by the condensation of gamma-
butyrolactone with methylamine followed by distillation to remove wa-
ter.

56 million lbs/yr manufactured in 1989 New facility expected to
produce 20 million lb/yr starting in 1990. 3 million lbs/yr imported in
1986 and 1987
2 in 1989, 3 in 1990

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

EVALUATION

Domain Metric

Rating

MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

High

X 1 1

EPA

Domain 2: Representative

Metric 2: Geographic Scope

Metric 3: Applicability

Metric 4: Temporal Representativeness

Metric 5: Sample Size

High
High
Low
N/A

X 1 1

x 2 2
x 2 6
N/A

Manufacturing in scope
1989

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1 1

Data sources included

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.6

Continued on next page

Page 647 of 691

-------
— continued from previous page

Source Citation:	Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	4214135

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 648 of 691

-------
Source Citation: Us, E. P. A.. 1989. SUMMARY ENGINEERING REPORT TEST RULES EXPOSURE ANALYSIS N-

METHYLPYRROLIDONE WITH COVER LETTER DATED 110189.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 4214135

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Use

Paint and coatings use and removers

Stripper applied to surface by spraying or brushing or dipping. Time
given to penetrate. Stripper removed, wiped or scraped.
5.5 - 8.3 million lbs/yr in 1989
200-500 facilities

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

EPA

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

Manufacturing in scope

Metric 4:

Temporal Representativeness

Low

1989

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

Data sources included

Domain 4: Variability and Uncertainty

Metric 7:

Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

Page 649 of 691

-------
Source Citation: Midwest Research Institute (MRI). 1998. Emission Factor Documentation for AP-42. Section 9.2.1: Fertilizer Application.

Draft Report.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5097883

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Fertilizer application

Methods of application are detailed in Section 2.2. Although many types
of fertilizers are manufactured, the basic application methods depend
on whether the fertilizer is in gaseous, fluid, or solid form. Methods for
application of each of these three forms of fertilizer are discussed.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

High

X 1

Prepared for EPA

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
Medium
N/A

X 1

x 2
x 2

2
4

N/A

In scope
1998

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Assessment or report clearly documents its data sources, as-
sessment methods, results, and assumptions

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

High

x 1

Includes discussion of limitations to these estimates/
information

Overall Quality Determination^

High

1.3

* MWF = Metric Weighting Factor

Page 650 of 691

-------
Source Citation:	Nondestructive Testing (NDT) Resource Center. 2017. What is NDT?.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	5097890

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Metal finishing

A nondestructive evaluation (NDE) method would not only locate a
defect, but it would also be used to measure something about that defect
such as its size, shape, and orientation. NDE may be used to determine
material properties, such as fracture toughness, formability, and other
physical characteristics

EVALUATION













Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability













Metric 1:

Methodology

Low

X

1

3

Data sources not specified

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2017

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity











Metric 6:

Metadata Completeness

Low

X

1

3

not fully transparent

Domain 4: Variability and Uncertainty











Metric 7:

Metadata Completeness

N/A





N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.6

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 651 of 691

-------
Source Citation:
Type of Data Source
Hero ID

Kemira. 2018. RE: N-Methylpyrrolidone (NMP) (CASRN 872-50-4). EPA-HQ-OPPT-2016-0743-0085.

Facility; Reports for Data or Information Other than Exposure or Release Data;

5176404

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Processing

Chemical processing, excluding formulation (polymer manufacturing) n-
Methylpyrrolidone (NMP) is an industrial solvent that is used in a very
narrow application. Specifically, it is the preferred solvent for phe-
nothaizine (PTZ), the short-stop chemical for glacial acrylic acid (GAA)
and glacial methamlic acid (GMA). In case of an uncontrolled polymer-
ization within the storage tank, the PTZ can be injected in an attempt
to stop this reaction and prevent a tank rupture.

65 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

1

2
2

N/A

US

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Variability and uncertainty in concentration not addressed.

Overall Quality Determination^

High



1.4



Continued on next page

Page 652 of 691

-------
— continued from previous page

Source Citation:	Kemira. 2018. RE: N-Methylpyrrolidone (NMP) (CASRN 872-50-4). EPA-HQ-OPPT-2016-0743-0085.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176404

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 653 of 691

-------
Source Citation: JSR and JSR Micro Inc.. 2017. Comments on the preliminary information on manufacturing, processing, use, and disposal:

N-Methylpyrrolidone (NMP). EPA-HQ-OPPT-2016-0743-0064.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176405

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

electronics

NMP is essential as a solvent in alignment film coatings because poly-
imide is soluble in very few other solvents. Used for LCD screen manu-
facturing. Alignment film coating is printed on the glass and baked to
remove various solvents. The volatile NMP during pre-bake and post-
bake process are removed by air emission abatement devices.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 654 of 691

-------
Source Citation: FUJIFILM Electronics Materials USA Inc.. 2017. NMP Use/Application Survey FFEM/FEUP. EPA-HQ-OPPT-2016-0743-

0024.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176406

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Batch Size:

Chemical Concentration:

Use

Electronics - semiconductor manufacturing

Processing aid that is not intended to become part of the final product;
Reactant (i.e., used by itself or with other monomers to synthesize an-
other substance); Formulant/additive; Cleaner/degreaser/surface prep
agent. Bulk containers, totes, drums, and bottles.

2 - Texas and California
batch process
10-100 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

2
2
2

In scope
2017

Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium

x 1

Limited information on concentration variability

Overall Quality Determination^

High

1.3

Continued on next page

Page 655 of 691

-------
— continued from previous page

Source Citation:	FUJIFILM Electronics Materials USA Inc.. 2017. NMP Use/Application Survey FFEM/FEUP. EPA-HQ-OPPT-2016-0743-

0024.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176406

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 656 of 691

-------
Source Citation: Saft American Inc.. 2017. Memorandum to EPA: N-methylpyrrolidone, docket ID number EPA-HQ-OPPT-2016-0743. EPA-

HQ-OPPT-2016-0743-0005.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176407

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):

Use

Electronics - batteries

NMP is used in the Saft "mixing" process whereas raw powder chemicals,
solvent (NMP), binder and substrates are combined to form a positive
mix.

In 2016 the Cockeysville plant used 46,022.69 kg. While the
Jacksonville plant used 296,651 kg

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

From chemical manufacturing company. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 657 of 691

-------
Source Citation: North America's Building Trades Unions (NABTU). 2017. Re: TSCA scoping and review: Ten priority chemicals. EPA-HQ-

OPPT-2016-0743-0023.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176408

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): all - list of uses in the construction industry

Process Description: adhesives and sealants; cleaners; coatings; strippers; Soldering flux,

which cleans oxidation from metals; wood preservatives

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Trade association poll of manufacturers. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 658 of 691

-------
Source Citation: Celanese Engineered Materials. 2017. N-methylpyrrolidone (NMP) CASRN: 872-50-4, use, disposal and exposure scenarios.

EPA-HQ-OPPT-2016-0743-0015.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176410

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Chemical Concentration:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
NMP is a solvent critical to manufacturing high-temperature poly-
mer Polyphenylene sulfide (PPS). NMP is a solvent used to dissolve
monomers allowing for a polymerization reaction. After use as a re-
action solvent, NMP is recovered in multiple distillation columns and
recycled back to storage tanks for reuse.

26.2 million lbs of PPS; 2,425,000 lbs of NMP in 2016
Residual NMP measured is below 17 ppm

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 From chemical manufacturing company. No bias /errors evi-

dent.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2017

Metric 5:

Sample Size

N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High x 1 1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Medium X 1 2 Limited information on concentration variability

Overall Quality Determination^ High 1.3

Continued on next page

Page 659 of 691

-------
— continued from previous page

Source Citation:	Celanese Engineered Materials. 2017. N-methylpyrrolidone (NMP) CASRN: 872-50-4, use, disposal and exposure scenarios.

EPA-HQ-OPPT-2016-0743-0015.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176410

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 660 of 691

-------
Source Citation:	Akin Gump Strauss Hauer & Feld LLP. 2018. Re: EPA docket EPA-HQ-OPPT-2016-0743: N-Methyl-2-pyrrolidone ("NMP"

CAS# 872-50-4 comments regarding the NMP problem formulation document. EPA-HQ-OPPT-2016-0743-0102.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176411

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

dip cleaning of plastic films

NMP is used to remove residual colorants from the surface of plastic films
following a coloring process. The plastic film, which is initially colored by
moving the material through a solvent" colorant solution, is cleaned of
excess colorant by processing the material through a wash basin
containing NMP. The NMP wash basins are open to allow film to move to
other units for further processing. The NMP in the basin is cooled to
minimize evaporation. After the NMP wash basins, the product is further
washed with water which is collected and routed to an on-site biological
treatment plant.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Low

X

1

3

Anonymous comment - data, data sources, and/or techniques
used in the assessment or report are not specified

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

XXX

1

2
2

1

2
2

N/A

US

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X

1

1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A





N/A

This metric is not applicable to this data type

Continued on next page

Page 661 of 691

-------
— continued from previous page

Source Citation:	Akin Gump Strauss Hauer & Feld LLP. 2018. Re: EPA docket EPA-HQ-OPPT-2016-0743: N-Methyl-2-pyrrolidone ("NMP"),

CAS# 872-50-4 comments regarding the NMP problem formulation document. EPA-HQ-OPPT-2016-0743-0102.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176411

EVALUATION

Domain

Metric

Rating MWF* Score

Comments



Overall Quality Determination^



High 1.3





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 662 of 691

-------
Source Citation: American Chemistry Council. 2017. American Chemistry Council comments on the U.S. Environmental Protection Agency's

initial 10 chemicals identified for risk evaluation. EPA-HQ-OPPT-2016-0743-0011.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176412

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Paints, coatings, adhesives

NMP is used as a coalescing aid in antistatic applications. By allowing
particles to coalesce into a more continuous film, NMP enhances an-
tistatic performance by a factor of ten or more compared to solutions
without NMP. NMP is used to control the viscosity of urethane coatings
in the process of making aqueous dispersions.

0.5 percent ; 5-15 percent ; <5 percent ; <1.5 percent ; <0.5 percent ;
<14 percent ; 30-50 percent ; <0.1 percent

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 ACC poll of trade association members. No bias /errors evi-

dent.

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High x 1 1 US

High X 2 2 In scope

High x 2 2 2017

Medium X 1 2 Range with uncertain statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High x 1

1 Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Medium x 1

2 Limited information on concentration variability

Overall Quality Determination^

High

1.3

Continued on next page

Page 663 of 691

-------
— continued from previous page

Source Citation:	American Chemistry Council. 2017. American Chemistry Council comments on the U.S. Environmental Protection Agency's

initial 10 chemicals identified for risk evaluation. EPA-HQ-OPPT-2016-0743-0011.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5176412

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 664 of 691

-------
Source Citation: American Chemistry Council. 2017. American Chemistry Council comments on the U.S. Environmental Protection Agency's

initial 10 chemicals identified for risk evaluation. EPA-HQ-OPPT-2016-0743-0011.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176412

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Processing

Chemical processing, excluding formulation (polymer manufacturing)
NMP is capable of dissolving difficult polymers. This makes it ideal
for applications such as dissolving polyester oligomers at an elevated
temperature and then precipitating them to form polyester beads.

High concentrations of NMP may be necessary

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

ACC poll of trade association members. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 665 of 691

-------
Source Citation: Alliance of Automobile Manufacturers. 2017. Re: Scope of risk evaluations for ten chemicals designated on December 19,

2016. EPA-HQ-OPPT-2016-0743-0035.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5176413

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

all - list of uses in the auto industry

According to a blinded analysis involving our members, this chemical
is used in the auto manufacturing process in painting, stripping, and
cleaning. The chemical is used in certain polymers, leather, adhesives,
coatings, bonding agents, inks, and paints in certain components.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

x 1

Trade association poll of manufacturers. No bias /errors evi-
dent.

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2017

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information is from the source

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

N/A

This metric is not applicable to this data type

Overall Quality Determination^

High

1.1

* MWF = Metric Weighting Factor

Page 666 of 691

-------
Source Citation: EaglePicher Technologies, LLC. 2020. Comments of EaglePicher Technologies, LLC on the draft TSCA risk evaluation of

n-methylpyrrolidone (NMP): EPA"HQ"OPPT-2019-0236.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592029

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Operating Days per Year and Batches per Day:

Use

Electronics manufacturing - Lithium Ion Battery

See process description starting on the bottom of page 1. In summary,
NMP is used in cathode and anode coatings as a carrier solvent. The
facility only receives sealed containers of virgin NMP and pre-mixed
binder-NMP solution. Coating is applied in enclosed system by a slot
die or reverse comma coating head. Once applied, NMP evaporates in
a negative pressure drying oven (emissions captured). NMP is not used
in cleaning.

One facility: 1,100 kg NMP/yr. Another facility: 800 kg NMP/yr

One facility: 1-2 bt/day, 3-4 days per week. Another facility: 1 bt/day,

3 days per week

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium X 1 2 Information from manufacturer of lithium ion batteries. No

bias /errors evident.

Domain 2: Representative

Metric 2:

Geographic Scope

High

Metric 3:

Applicability

High

In scope

Metric 4:

Temporal Representativeness

High

2020

Metric 5:

Sample Size

Low

Characterized by no statistics

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High X 1 1 Information provided is firsthand information from industrial

user(s) of NMP

Continued on next page

Page 667 of 691

-------
— continued from previous page

Source Citation:	EaglePicher Technologies, LLC. 2020. Comments of EaglePicher Technologies, LLC on the draft TSCA risk evaluation of

n-methylpyrrolidone (NMP): EPA"HQ"OPPT-2019-0236.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592029

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 Does not address variability or uncertainty

Overall Quality Determination^

High

1.6



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 668 of 691

-------
Source Citation: LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592033

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Possible Physical Form:

Use

Electronics manufacturing - Lithium Ion Battery

In the manufacturing of lithium ion cells, NMP is used only as a carrier
for the binder resin used to form the cathode (and to a lesser extent,
the anode) component of the cell. NMP is mixed with powder chemicals
and binders, and then the solution is coated onto thin metal foils with
a precise automated roll coating process /pumped to a coating die-head
and deposited onto a foil current collector. The wet coated foil is passed
through a drying oven to drive off the liquid. NMP is not a final compo-
nent in lithium ion cells, (description pg 5-15). The handling of NMP in
small containers in cell manufacturing facilities is limited to infrequent
use in the laboratory or small-scale operations where they are opened
only in ventilated hood areas with personnel equipped with extensive
PPE for no more than 30 minutes a shift. NMP is not typically han-
dled in drums. NMP is delivered to most lithium ion cell manufacturing
facilities by rail car and/or semi-trailer truck.

NMP used for lithium ion cell making has substantially lower
moisture content

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information is from a trade association of manufacturers. No
bias /errors evident

Domain 2: Representative
Metric 2
Metric 3
Metric 4

Geographic Scope High x 1 1 US

Applicability High x 2 2 in scope

Temporal Representativeness High x 2 2 2020

Continued on next page

Page 669 of 691

-------
— continued from previous page

Source Citation:	LICM. 2020. Comment on docket no. EPA-HQ-OPPT-2019-0236, Toxic Substances Control Act (TSCA) draft risk evaluation

for n-methylpyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592033

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 5: Sample Size

N/A



N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 670 of 691

-------
Source Citation: LICM . 2020. Conference call with Lithium Ion Cell Manufacturers" Coalition (LICM) on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0114.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592025

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics manufacturing - Lithium Ion Battery

Large sites: NMP distillation -> cathode slurry mixing -> cathode
slurry coating -> cathode drying -> NMP collection and recycle to
distillation process so that it can be reused. Small sites: NMP truck
delivery of small containers (1-gal). Small volume of NMP waste is
produced and packaged into drums and hauled off-site for hazardous
waste disposal.

99.8 percent

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope High x 1

Applicability High x 2

Temporal Representativeness High x 2

Sample Size Medium x 1

1 US

2 In scope
2 2020

2 NMP concentration data provided as single data point. Uncer-

tain statistics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High X 1 1 Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness Low X 1 3 Does not address variability or uncertainty

Continued on next page

Page 671 of 691

-------
— continued from previous page

Source Citation:	LICM . 2020. Conference call with Lithium Ion Cell Manufacturers" Coalition (LICM) on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0114.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592025

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Overall Quality Determination^



High 1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 672 of 691

-------
Source Citation: LICM . 2020. Conference call with Lithium Ion Cell Manufacturers" Coalition (LICM) on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0114.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592025

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics manufacturing - Lithium Ion Battery

Virgin NMP truck unloading occurs only at large sites. Third party
vendor transfers from tanker trucks to large, exterior tanks. Employees
may set up safety perimeter, ensure safety during unloading process,
and assist the driver at the beginning and end of the process. //Small
container unloading occurs at small sites. DOT-compliant boxes of 1-
gallon containers of NMP, securely stored. Small containers used to
prep mixture components for mixer or any small container use. //Waste
loading into drums occurs only at small sites. Drums torqued to seal and
moved on drum dolly to storage location until third-party vendor loads
truck for disposal. //Slurry mixing occurs in semi-automated process
at small sites and fully automated process at large sites. NMP added to
slurry as a carrier. Slurry mixture containing NMP mixed for consistency
prior to application to metal foil. //Coating and drying occurs as fully
automated process at both small and large sites. //Maintenance occurs
at both small and large sites and includes parts washing, equipment
adjustments and repairs, and other non-routine tasks.

>99 percent (virgin NMP - unloading from various containers), <=60
percent (waste NMP loading, slurry mixing, cathode coating)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:

Geographic Scope
Applicability

High
High

X 1

x 2

In scope

Continued on next page

Page 673 of 691

-------
— continued from previous page

Source Citation:	LICM . 2020. Conference call with Lithium Ion Cell Manufacturers" Coalition (LICM) on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0114.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592025

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 4: Temporal Representativeness
Metric 5: Sample Size

High
Medium

x 2
x 1

2
2

2020

NMP concentration data provided as single data points. Un-
certain statistics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 674 of 691

-------
Source Citation: EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592024

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Use

Electronics manufacturing - Lithium Ion Battery

Made in small batches production is not continuous. Cathodes and
anodes are made from metal powders that are dissolved in NMP, which
serves as a "binder" solution. At the Joplin site, NMP arrives in small
premixed metal containers (4 gal) or pure NMP (1 gal); at the Greenwich
site, NMP arrives in 55-gal drums, which are connected to a valve ->
added to mixer -> blending -> transferred to tank, then coater/dryer
-> NMP driven off during coating/drying process
Joplin MO site: 1,100 kg/yr Greenwich, RI: 800 kg/
yr 2 that use NMP: Joplin, MO and Greenwich, RI

EVALUATION

Domain

Metric

Rating MWF* Score

Comments

Domain 1: Reliability

Metric 1: Methodology

Medium x 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2
Metric 3
Metric 4
Metric 5

Geographic Scope High

Applicability High

Temporal Representativeness High

Sample Size Medium

x 1 1 US

X 2 2 In scope

X 2 2 2020

X 1 2 PV data provided as single data point for each site. Uncertain

statistics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness High X 1 1 Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Continued on next page

Page 675 of 691

-------
— continued from previous page

Source Citation:	EaglePicher Technologies, LLC. 2020. Conference call with EaglePicher Technologies on n-methylpyrrolidone. EPA-HQ-

OPPT-2016-0743-0113.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592024

EVALUATION

Domain Metric

Rating

MWF* Score Comments

Metric 7: Metadata Completeness

Low

X 1 3 Does not address variability or uncertainty

Overall Quality Determination^

High

1.4



* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 676 of 691

-------
Source Citation: FUJIFILM Holdings America Corporation. 2020. FUJIFILM comments for docket ID # EPA-HQ-OPPT-2019-0236 for

CASRN 872-50-4, n-methylpyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592030

EXTRACTION

Parameter Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Total Annual U.S. Volume (and percent of PV):
Number of Sites:

Batch Size:

Possible Physical Form:

Chemical Concentration:

Processing

Formulation into solutions for electronics industry

NMP is used as a formulant /additive in industrial products- variety
of inks, adhesives, coating and other products. Water base adhesives,
water base laminating clears, screen printing inks, and screen reclama-
tion chemicals. NMP is received in rail cars (28,000 gal), tanks (5,000
gal), totes (330 gal), drums (55 gal), and bottles (1 gal). Formulations
leave in the same types of containers. //At MO site: A mixture of sev-
eral chemicals including NMP are added to an open mixing vessel and
blended using a high speed disperser. The blending conditions are at
ambient temperature and pressure. The finished product is gravity dis-
pensed or with use of a pneumatic pump into 1 gallon, 5 gallon, and 55
gallon containers.

At MO site: Annual usage is approximately 21,000 lbs
4 - North Kingstown RI, Carrollton TX, Greenwood SC and North
Kansas City MO

At MO site: Maximum batch size of 300 gallons
liquid

In all products: 10 to 100 percent In printing ink at MO site: 10 to 25
percent

EVALUATION

Domain Metric Rating MWF* Score Comments

Domain 1: Reliability

Metric 1: Methodology Medium X 1 2 Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2: Geographic Scope High x 1 1 US

Metric 3: Applicability High x 2 2 In scope

Continued on next page

Page 677 of 691

-------
— continued from previous page

Source Citation:	FUJIFILM Holdings America Corporation. 2020. FUJIFILM comments for docket ID # EPA-HQ-OPPT-2019-0236 for

CASRN 872-50-4, n-methylpyrrolidone (NMP).

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592030

EVALUATION

Domain Metric

Rating

MWF*

Score

Comments

Metric 4: Temporal Representativeness
Metric 5: Sample Size

High
Medium

x 2
x 1

2
2

2020

PV and concentration data provided as single data point or
range. Uncertain statistics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 678 of 691

-------
Source Citation: Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 5161295

EXTRACTION

Parameter Data

Life Cycle Stage: Use

Life Cycle Description (Subcategory of Use): Electronics manufacturing - semiconductor manufacturing

Process Description: Drums used for waste. Waste drum Disconnect, Removal, Handling

(55 gal). //Small containers include 1 gal containers, 4L and 10L
NOWPAKs, 20L containers, and 5-gal plastic totes. //Maintenance
includes parts cleaning, filter change out, preventative maintenance. //
Virgin NMP truck off-loading: Pull 6 samples for purity analysis; trans-
fer of virgin NMP from a 10,000 gallon tanker truck to a 10,000 gallon
tank in the tank farm. Turn on pump; stay in enclosure upstairs during
2 hour transfer. //Waste truck loading: Transfer of approximately 5,000
gallons of NMP waste from a 10,000 gallon tank to a tanker truck.

Chemical Concentration: 20-75 percent (drum handling); 40-75 percent (small container handling);

1-100 percent (maintenance); 100 percent (virgin NMP truck unloading);
92 percent (waste truck loading)

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2018

Metric 5:

Sample Size

Medium

x 1

Data provided as single data point or range. Uncertain statis-

tics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6:

Metadata Completeness

High

x 1

Information provided is firsthand information from industrial

user(s) of NMP

Continued on next page

Page 679 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2019. NMP Supplemental Data: Container Handling.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	5161295

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 Does not address variability or uncertainty

Overall Quality Determination^	High	1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 680 of 691

-------
Source Citation:	3986801".

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3986801

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Number of Sites:

Operating Days per Year and Batches per Day:
Chemical Concentration:

Use

Electronics manufacturing - semiconductor manufacturing
NMP is used in semiconductor manufacturing for three main purposes:
1. Solvent (<5 wt. percent NMP) in certain semiconductor chemi-
cal formulations which are deposited on the wafer via spin processes in
photolithography including photoresists, bottom anti-reflective coatings
(BARC), and in spin-coated polyimides (?60 wt. percent NMP); 2. Sol-
vent pre-wet (>90 wt. percent NMP) of wafers prior to application of
spin on coatings in photolithography; 3. Solvent (between 30-60 or >90
wt. percent NMP) in wafer cleaning and stripping formulations in wet
area. NMP (? 100 wt. percent) is used in some maintenance activities
to clean equipment parts. Small quantities of 100 percent NMP also are
used in semiconductor analytical laboratories.

51 large semiconductor manufacturing facilities were operated in 2017
(NMP is not used in all fabs); in 21 states
24 hrs/day; 365 days/yr; 8-12 hr shifts

Same data as 516295; Photolithography formulations contain <5 percent
NMP; Wet cleans/stripper solutions contain between 30-60 or >90 wt.
percent NMP; 100 percent NMP Pre-wet layer; 30-60 percent NMP in
the polyimide coating layer

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X

1

2

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative













Metric 2:

Geographic Scope

High

X

1

1

US

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2019

Continued on next page

Page 681 of 691

-------
— continued from previous page

Source Citation:	3986801".

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;
Hero ID	3986801

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 5: Sample Size

Medium

X 1

2

Data provided as single data point or range. Uncertain statis-
tics and unclear if representative.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 682 of 691

-------
Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592032

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics manufacturing - semiconductor manufacturing
Small container handling involved container change out from chemical
delivery systems. Drum handling involves inserting and removing dip
tubes from drums. Fab workers include photolithography operators who
may change out small containers of photoresist that contain NMP.
Maintenance includes tool cleaning, filter change outs, and other activi-
ties. Virgin NMP truck unloading requires sampling and line connection/
disconnection. Waste truck loading involves sampling, transfer hose op-
eration, and removal of residual with pressurized air.

50 (central tendency) 75 percent (high-end) (drum handling); 60 (CT)
75 percent (HE) (small container handling); 0.025 (CT) 0.05 (HE) (fab
worker with container change out); 0.5 (CT) 100 percent (HE)
(main-tenance); 100 percent (CT and HE) (virgin NMP truck
unloading); 92 percent (CT and HE) (waste truck loading)

EVALUATION













Domain

Metric

Rating

MWF*

Score



Comments

Domain 1: Reliability













Metric 1:

Methodology

Medium

X 1

2

Information is

from a manufacturer. No bias /errors evident

Domain 2: Representative













Metric 2:

Geographic Scope

High

X 1

1

US



Metric 3:

Applicability

High

x 2

2

In scope



Metric 4:

Temporal Representativeness

High

x 2

2

2020



Metric 5:

Sample Size

Medium

x 1

2

Data provided

as single data point or range. Uncertain statis-

tics and unclear if representative.

Domain 3: Accessibility/Clarity

Continued on next page

Page 683 of 691

-------
— continued from previous page

Source Citation:	Semiconductor Industry Association (SIA). 2020. Comments of the Semiconductor Industry Association (SIA) on the draft

Toxic Substances Control Act (TSCA) risk evaluation for n-methylpyrrolidone (NMP). EPA-HQ-OPPT-2019-0236-0052.
Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592032

EVALUATION









Domain Metric

Rating

MWF*

Score

Comments

Metric 6: Metadata Completeness

High

X 1

1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

X 1

3

Does not address variability or uncertainty

Overall Quality Determination^

High



1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 684 of 691

-------
Source Citation:	Hach Company. 2020. Hach's comments regarding the draft Toxic Substances Control Act (TSCA) risk evaluation for

n-methylpyrrolidone (NMP), EPA docket EPA-HQ-OPPT-2019-0236.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592027

EXTRACTION

Parameter	Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Laboratory

NMP is an ingredient in the Hach product, Silver 2 Reagent Solution
Pillows. This laboratory reagent is sold only in unit-dose packaging
containing < 5 mL solution per test. One package is opened and poured
into a 50-mL mixing cylinder containing powdered Silver 1 Reagent, and
the mixing cylinder swirled to dissolve the powder. Once the powder has
dissolved, a 50-mL water sample is poured from a graduated cylinder into
the mixing cylinder, which is stoppered and inverted to mix.

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Domain 1: Reliability

Metric 1: Methodology	Medium X 1	2 Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

X

1

1

us

Metric 3:

Applicability

High

X

2

2

In scope

Metric 4:

Temporal Representativeness

High

X

2

2

2020

Metric 5:

Sample Size

N/A





N/A

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness	High	X 1	1 Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness	Low	X 1	3 Does not address variability or uncertainty

Overall Quality Determination^	High	1.4

Continued on next page

Page 685 of 691

-------
— continued from previous page

Source Citation:	Hach Company. 2020. Hach"s comments regarding the draft Toxic Substances Control Act (TSCA) risk evaluation for

n-methylpyrrolidone (NMP), EPA docket EPA-HQ-OPPT-2019-0236.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592027

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 686 of 691

-------
Source Citation:
Type of Data Source
Hero ID

National Electrical Manufacturers Association. 2020. NMP use in magnet wire. EPA-HQ-OPPT-2019-0236-0047.

Facility; Reports for Data or Information Other than Exposure or Release Data;

6592028

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Chemical Concentration:

Use

Electronics - magnet wires

NMP is used as a solvent/diluent in high-performance magnet wire
enamels, thinners, and cleaners. In the magnet wire industrial process,
a copper or aluminum wire is routed through an applicator of solvent-
based enamel coating. The size of applicator may vary throughout the
industry, but most contain " 1 gallon of coating, which contains at most
80-85 percent concentration of NMP. After the wire exits the curing oven
on its final pass, the newly-enameled wire is given a lubricant coating to
aid in coil winding by the customer. The finished product contains only
trace amounts of NMP due to the curing process previously described.
In addition to the application and curing process, another facet to mag-
net wire manufacturing is maintenance cleaning. Enameling equipment
is bathed in agitated tanks of NMP.

80-85 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative

Metric 2:

Geographic Scope

High

X 1

Metric 3:

Applicability

High

x 2

In scope

Metric 4:

Temporal Representativeness

High

x 2

2020

Metric 5:

Sample Size

Medium

x 1

Concentration provided as a range. Uncertain statistics and

unclear if representative.

Domain 3: Accessibility/Clarity

Continued on next page

Page 687 of 691

-------
— continued from previous page

Source Citation:
Type of Data Source
Hero ID

National Electrical Manufacturers Association. 2020. NMP use in magnet wire. EPA-HQ-OPPT-2019-0236-0047.

Facility; Reports for Data or Information Other than Exposure or Release Data;

6592028

EVALUATION

Domain

Metric

Rating

MWF* Score

Comments



Metric 6; Metadata Completeness

High

X 1 1

Information provided is firsthand information from industrial

user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1 3

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4





* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 688 of 691

-------
Source Citation:
Type of Data Source
Hero ID

ACA. 2020. American Coatings Association submittal to NMP docket: EPA-HQ-2016-0743.
Facility; Reports for Data or Information Other than Exposure or Release Data;

6592043

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Batch Size:

Site Daily Throughput:
Chemical Concentration:

Processing
Formulation of paint

Mixing occurred in a closed system with NMP being pumped in, as is

common for mixing of paints. Mixed in a closed, "small batch" system,

with 6 ports on the lid that remain closed throughout loading, mixing

and unloading. These ports consist of four 2" ports, one 3" port, and

one 6" port.

500 gallon batch

163 lbs. (19.1 gallons)/batch

100.00 percent

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

2

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High
Medium

X 1

x 2
x 2
x 1

1

2
2
2

US

In scope
2018

Concentration and throughput provided as single values for one
batch. Uncertain if this is representative of the site's opera-
tions or operations at other sites.

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

3

Does not address variability or uncertainty

Continued on next page

Page 689 of 691

-------
— continued from previous page

Source Citation:	ACA. 2020. American Coatings Association submittal to NMP docket: EPA-HQ-2016-0743.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID	6592043

EVALUATION

Domain	Metric	Rating MWF* Score	Comments

Overall Quality Determination^	High	1.4

* MWF = Metric Weighting Factor

t If any individual metrics are deemed Unacceptable, then the overall rating is also unacceptable. Otherwise, the overall rating is based on the following scale:
High: > 1 to < 1.7; Medium: > 1.7 to < 2.3; Low: > 2.3 to < 3.

Page 690 of 691

-------
Source Citation: LICM. 2020. Supplemental NMP information to document PPE protection for submission to docket from Lithium Ion Cell

Manufacturers. EPA-HQ-OPPT-2016-0743-0116.

Type of Data Source Facility; Reports for Data or Information Other than Exposure or Release Data;

Hero ID 6592044

EXTRACTION
Parameter

Data

Life Cycle Stage:

Life Cycle Description (Subcategory of Use):
Process Description:

Use

Electronics - lithium ion battery

The NMP serves as a carrier for the binder resin in the slurry. The
coated foil passes through dryers where the NMP is recovered. NMP
does not remain in or on the lithium ion electrode or the final cell after
the drying stage of the electrode manufacturing process.

EVALUATION

Domain

Metric

Rating

MWF*

Score

Comments

Domain 1: Reliability

Metric 1:

Methodology

Medium

X 1

Information is from a manufacturer. No bias /errors evident

Domain 2: Representative
Metric 2:
Metric 3:
Metric 4:
Metric 5:

Geographic Scope
Applicability

Temporal Representativeness
Sample Size

High
High
High

N/A

X 1

x 2
x 2

2
2

N/A

In scope
2020

This metric is not applicable to this data type

Domain 3: Accessibility/Clarity

Metric 6: Metadata Completeness

High

x 1

Information provided is firsthand information from industrial
user(s) of NMP

Domain 4: Variability and Uncertainty

Metric 7: Metadata Completeness

Low

x 1

Does not address variability or uncertainty

Overall Quality Determination^

High

1.4

* MWF = Metric Weighting Factor

Page 691 of 691

-------