Approach

Issue

Key Outputs

Aluifing Science

jjito Anion

Organophosphates (OPs)

Dichlorvos
Methamidophos
cis, trans, total Mevinphos
Acephate

Naled
Demeton-S
Fonofos
Diazinon
Diazinon oxon
Disulfoton
Dimethoate
Methyl Parathion

Chlorpyrifos
Malathion oxon
Chlorpyrifos oxon
Malathion
Ethyl Parathion
Methidathion
Ethion
Phosmet
Azinphos-methvl

Pyrethroids

cis, trans, total Allethrin
Resmethrin
Bifenthrin
Sumithrin
Tetramethrin I, II, total
lamda-Cyhalothrin
cis, trans, total Permethrin

Pyrethrin I, II
Cyfluthrin I, II, III, IV, total
Cypermethrin I, II, III, IV, total
Esfenvalerate
Delta/Tralomcthrin

Applicator

No. Applications
Last 6 months

Where Applied

Kitchen, Outdoors
LR, BR, BA

Self/Family

Aerosol, fogger
spray, baits, gels

Collaborative project with CDC and the Duval County Health Department (DCHD)

Designed as a three-tiered approach

—	Tier 1: Recruitment of 200 children into the study, completion of a questionnaire, collection of urine samples

—	Tier 2: Collection of environmental screening samples from 25% of the participants in tier 1
° Pesticide inventory, surface wipes, transferable residues, time-activity diary, urine

—	Tier 3: Detailed exposure assessment in 9 homes from tier 2

° Surface wipes, transferable residues, indoor/outdoor air, time-activity diary, pesticide residues
on cotton socks, duplicate diet, urine
Participation in tier 2 was dependent on the answers to the questions in the initial questionnaire on the frequency
of use of pesticdes

Participation in tier 3 was dependent on both the answers to the pesticide-related questions in the initial
questionnaire and the presence of pesticides in the home verified by a screening inventory

Professional

Aerosol, fogger
spray, baits, gels

Kitchen, laundry
	BR, BA

Children are more vulnerable to pesticide
exposures and these exposures may result in both
short- and long-term health effects
To address the Agency's goal of providing
children with a safe and healthy environment,
special childhood vulnerabilities to environmental
contaminants must be considered in risk
assessments

The Food Quality Protection Act of 1996 (FQPA)
requires that children's aggregate exposures to
pesticides be considered during the tolerance-
setting process

Children's exposure and exposure factor data are
very limited and require risk assessors to rely on
conservative default assumptions in the regulatory
process

Children's exposure studies, especially for very
young children, are required to generate critical
exposure data and characterize activities and
exposure factors that contribute to aggregate

exposure

Frequency of pesticide use and locations

where pesticides are applied

Phenyl-Pyrazole

Fipronil

Synergist

Piperonyl butoxide

Pesticides targeted for quantitation

Successful community-based collaboration

between DCHD, CDC, and EPA

Knowledge of the current-use pesticides in the

greater Jacksonville, FL area

Data that reduce the risk assessor's reliance

on default parameters in exposure and risk

assessments for pesticides

Identifying critical factors influencing children's

exposures to pesticides

Electronic databases of children's exposures

Educational materials for public use

•	Community-based collaborative efforts between federal and state agencies result in very successful
studies

•	EPA's regulations will be based on high quality, real world children's exposure and exposure factor
data that reduces the reliance on conservative default assumptions and addresses special childhood
vulnerabilities to environmental contaminants

•	Children's exposure and exposure factor data will be readily available to identify critical exposure
issues, generate new research hypotheses, and also to develop risk management strategies to
reduce future exposures to pesticides

Partner Jug to protect tinman }Jeuhh and the environment


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