Approach Issue Key Outputs Aluifing Science jjito Anion Organophosphates (OPs) Dichlorvos Methamidophos cis, trans, total Mevinphos Acephate Naled Demeton-S Fonofos Diazinon Diazinon oxon Disulfoton Dimethoate Methyl Parathion Chlorpyrifos Malathion oxon Chlorpyrifos oxon Malathion Ethyl Parathion Methidathion Ethion Phosmet Azinphos-methvl Pyrethroids cis, trans, total Allethrin Resmethrin Bifenthrin Sumithrin Tetramethrin I, II, total lamda-Cyhalothrin cis, trans, total Permethrin Pyrethrin I, II Cyfluthrin I, II, III, IV, total Cypermethrin I, II, III, IV, total Esfenvalerate Delta/Tralomcthrin Applicator No. Applications Last 6 months Where Applied Kitchen, Outdoors LR, BR, BA Self/Family Aerosol, fogger spray, baits, gels Collaborative project with CDC and the Duval County Health Department (DCHD) Designed as a three-tiered approach — Tier 1: Recruitment of 200 children into the study, completion of a questionnaire, collection of urine samples — Tier 2: Collection of environmental screening samples from 25% of the participants in tier 1 ° Pesticide inventory, surface wipes, transferable residues, time-activity diary, urine — Tier 3: Detailed exposure assessment in 9 homes from tier 2 ° Surface wipes, transferable residues, indoor/outdoor air, time-activity diary, pesticide residues on cotton socks, duplicate diet, urine Participation in tier 2 was dependent on the answers to the questions in the initial questionnaire on the frequency of use of pesticdes Participation in tier 3 was dependent on both the answers to the pesticide-related questions in the initial questionnaire and the presence of pesticides in the home verified by a screening inventory Professional Aerosol, fogger spray, baits, gels Kitchen, laundry BR, BA Children are more vulnerable to pesticide exposures and these exposures may result in both short- and long-term health effects To address the Agency's goal of providing children with a safe and healthy environment, special childhood vulnerabilities to environmental contaminants must be considered in risk assessments The Food Quality Protection Act of 1996 (FQPA) requires that children's aggregate exposures to pesticides be considered during the tolerance- setting process Children's exposure and exposure factor data are very limited and require risk assessors to rely on conservative default assumptions in the regulatory process Children's exposure studies, especially for very young children, are required to generate critical exposure data and characterize activities and exposure factors that contribute to aggregate exposure Frequency of pesticide use and locations where pesticides are applied Phenyl-Pyrazole Fipronil Synergist Piperonyl butoxide Pesticides targeted for quantitation Successful community-based collaboration between DCHD, CDC, and EPA Knowledge of the current-use pesticides in the greater Jacksonville, FL area Data that reduce the risk assessor's reliance on default parameters in exposure and risk assessments for pesticides Identifying critical factors influencing children's exposures to pesticides Electronic databases of children's exposures Educational materials for public use • Community-based collaborative efforts between federal and state agencies result in very successful studies • EPA's regulations will be based on high quality, real world children's exposure and exposure factor data that reduces the reliance on conservative default assumptions and addresses special childhood vulnerabilities to environmental contaminants • Children's exposure and exposure factor data will be readily available to identify critical exposure issues, generate new research hypotheses, and also to develop risk management strategies to reduce future exposures to pesticides Partner Jug to protect tinman }Jeuhh and the environment ------- |