E PA/601/F24/003

*>EPA

United States
Environmental
Protection Agency

epa.gov/research

Introduction

EPA's Experimental Stream Facility (ESF) is one of
only a few research facilities in the United States
designed for conducting ecotoxicology research using
stream mesocosms, which are experimental systems
designed to simulate the natural environment but under
tightly controlled conditions indoors. A precisely
controlled setup allows for dose-response studies that
can evaluate and validate the effects of suspected
contaminants on native biotic stream communities.
The facility allows researchers to study the impacts of
emerging contaminants, mixtures, and nutrient pollution
on multiple interacting species. ESF is also used to
conduct studies related to water quality standards and
the establishment of aquatic life criteria. This research
helps inform decisions and management practices that
affect the biodiversity and health of streams and their
watersheds.

ESF research supports EPA's National Research
Programs, which provide the scientific foundation for
decision-making to safeguard human health and the
environment. Mesocosm studies at ESF are designed
in response to EPA program office, partner, and stake-
holder needs.

Facility and Staff

Facility: ESF includes 3,800 square feet of laboratory,
office, and research space, and is on long-term lease
from Clermont County, Ohio. The facility sits adjacent
to the Lower East Fork - Little Miami River Regional
Waste Water Treatment Plant, on land in the upper
floodplain terrace of the lower East Fork of the Little
Miami River watershed.

Staff: ESF houses three full time federal employees
and contractors. During experiments additional
scientific and support staff are on site.

Mesocosm

An experimental system that examines the natural
environment under controlled conditions. ESF stream
mesocosms are colonized with native species to
provide a realistic model of riffle/run habitat of a
natural stream. Mesocosm studies are designed to
assess effects on biotic communities and provide a
link between field surveys and bench-top laboratory
experiments.

Capabilities

ESF contains analytical equipment and instrumentation
used to link pollutant loads to in-stream biological
conditions. Several features that make the ESF unique
among stream mesocosm facilities include:

•	An indoor setup of sixteen 28-foot stream channels
that can be dosed independently of one another;

•	Multiple continuous water sources, including a
natural source from the river, reverse osmosis
treated tap water, and final treated effluent from the
adjacent wastewater treatment plant. Each source
can be precisely metered to produce different
mixing conditions;

Experimental set up and sampling in the mesocosms

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Facility Contact: Dr. Chris Nietch, nietch.christopher@epa.gov

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Watershed Research & Cooperative

The ESF serves as a base of operations for the East
Fork of the Little Miami River Watershed Study
(EFWS) — a case study that supports a long-term
water quality monitoring program, numerous field
studies, and watershed-scale analyses. The ESF sits
at the downstream end of the East Fork of the Little
Miami River Watershed.

The EFWS research is managed by the East Fork
Watershed Cooperative, a multi-agency partnership
that includes scientists, engineers, water resource
professionals, and stakeholders. Through the EFWS,
the Cooperative co-produces research on the utility of
watershed management models, addresses the risks
posed by harmful algae in its multi-use reservoir
(Harsha Lake), minimizes excess nutrient runoff and
other contaminants of concern, works to protect
drinking source water, and designs and implements
innovative agricultural best management practices for
reducing nutrient pollution.

Science Contributions

The unique research conducted at ESF identifies links between environmental stressors in stream flow and the
structure and function of stream ecosystems. ESF is used by scientists to understand interactions between
environmental stressors and stream organisms, and to predict the movement and transformation of pollutants in
surface water.

Continuous water quality monitoring;

High and low intensity grow lights to simulate open
canopy and shaded forest canopy sunlight;

Protocols for capturing macroinvertebrate drift and
insect emergence and assessing the micro- and
macroorganism communities at the whole
mesocosm scale;

Chemical dosing system for precise delivery of
chemicals/stressors and influent mixing; and

Supervisory Control and Data Acquisition
system consisting of water quality sensors, valves,
and meters to set experimental triggers, automate
data collection, and monitor and control flows,
lights, and chemical delivery.

Active research topics include:

•	Testing that supports nutrient criteria development
for the protection of aquatic life.

•	Freshwater oil spill simulations and tracking of
ecological consequences.

•	Methods development for assessing risks posed by
harmful algal blooms.

•	Development of DNA-based indicators for stream
bioassessment.

Notable scientific products & achievements in-
clude:

•	Studies that demonstrated the effects of antimicro-
bials on stream biotic communities, including
increases in antimicrobial resistance and
ecological impacts, which contributed to the
removal of Triclosan from soap products.

•	Validating a field benchmark proposed for streams
receiving discharges of excess major ions from
mines.

•	Designing a parallel single-species exposure
format that helps validate the appropriateness of
laboratory toxicity assays.

•	Testing new methods for contaminant sensing and
means of measuring important biological process
in situ,

•	Incorporating community-level endpoints that
inform effects on stream functional responses.

•	Determining natural stream processes important to
the utility of DNA-based indicators of fecal
pollution.

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