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INNOVATIVE RESEARCH FOR A SUSTAINABLE FUTURE

PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS)

EPA Research Summary

PFAS in the Environment

Per- and polyfluoroalkyl substances (PFAS) are a
group of synthetic chemicals that have been in use
since the 1940s. PFAS are found in a wide array of
consumer and industrial products. PFAS
manufacturing and processing facilities, facilities
using PFAS in production of other products, airports,
and military installations are some of the contributors
of PFAS releases into the air, soil, and water. Due to
their widespread use and persistence in the
environment, most people in the United States have
been exposed to PFAS. There is evidence that
continued exposure above specific levels to certain
PFAS may lead to adverse health effects.

EPA is supporting states, tribes, and local
communities in addressing human health concerns
related to PFAS. In response to requests for support
on PFAS, EPA researchers are developing analytical
chemistry methods to detect and quantify PFAS in
environmental media; gathering and assessing data
on chemical toxicity and environmental exposures for
PFAS of highest concern; and summarizing data and
conducting studies to determine the effectiveness and
the cost of different technologies for treating or
removing PFAS in drinking water and contaminated
sites.

Developing and Validating Analytical
Methods

EPA researchers are developing and validating
laboratory methods to detect and quantify selected
PFAS in air, water, and soil. EPA recently released a
revised version of EPA Method 537.1 for additional
PFAS (e.g. Flexafluoropropylene oxide dimer acid
(HFPO-DA), a GenX chemical) in drinking water.

Currently, EPA researchers are working on:

•	Validating methods under EPA's SW-846
Compendium to measure certain PFAS

in groundwater, surface water, wastewater,
and solids (e.g., soils, sediments, and
sewage).

•	Developing and testing sampling and
analytical methods for identifying and
quantifying PFAS in air and stack emissions.

•	Extending the use of non-targeted chemical
analysis for air emissions and solids.

Tested and validated methods are important for
ensuring that government and private laboratories can
accurately and consistently identify and measure
PFAS in the environment, which is critical for
estimating exposure and risk. These methods can be
used by federal agencies, states, tribes, and local
communities.

Assessing PFAS Toxicity

EPA researchers are developing standard human
health toxicity reference values for specific PFAS
where sufficient scientific data exist. These values
will enable risk assessors in states, tribes, and local
communities, in conjunction with knowledge on
exposure, to assess the risks and make decisions

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U.S. Environmental Protection Agency

Office of Research and Development


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about managing PFAS to protect human health and
the environement. EPA researchers are also applying
computational and high throughput toxicology tools
for PFAS toxicity testing on a larger scale to enable
faster understanding of potential toxicity for the
universe of thousands of PFAS, most of which have
little or no published toxicity data.

Researching PFAS Exposure

EPA researchers are measuring PFAS in air, drinking
water, soils, etc., to understand how and to what
degree people might be exposed to PFAS. This
research includes modeling human population
exposures to better understand the relative
contributions of different sources and pathways for
PFAS. This will help states, tribes, and local
communities to assess potential risks and, as
necessary choose the most effective methods for
protecting public health.

Testing Drinking Water Treatment Methods

EPA researchers continue to evaluate different
drinking water treatment technologies that can
remove certain PFAS from drinking water systems.
They are evaluating systems across the nation
currently treating PFAS and gathering data on cost
and performance. Researchers are also testing
modifications needed to improve treatment. This
research is being conducted in cooperation with
drinking water utilities and with other federal
agencies.

Researchers will generate performance and cost data
with collaborators to develop models and provide
tools to enable local communities to determine
optimal treatment choices based on their specific
needs and circumstances.

Cleaning Up Contaminated Sites

EPA researchers are developing methods for
characterizing PFAS releases and movement in soil,
water, and sediments at contaminated sites, so that
site managers can understand the scope and
magnitude of such contamination in order to decide
how best to respond. Researchers are also
developing and testing methods for treating,
removing, or immobilizing PFAS at such sites, to
provide site managers with tools for site remediation.
Some of this work is being done in collaboration with
the Department of Defense on current and former
military bases.

Managing PFAS Containing Materials and
Waste

EPA researchers are characterizing how end-of-life
disposal approaches, such as landfills, incinerators,
and recycling might contribute to PFAS in the
environment.

They are also evaluating waste management
technologies such as thermal treatment and
composting, that may be useful and cost-effective to
manage consumer and industrial products at end-of-
life disposal.

CONTACT

Andrew Gillespie, PhD
gillespie.andrew@epa.gov
For more information:

https://www.epa.gov/pfas/epa-pfas-data-and-tools

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U.S. Environmental Protection Agency

Office of Research and Development


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