Cost Estimates of Studies Required for Pesticide Registration April 2022 Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 810.1000 0.0000 Overview, Definitions, and General Considerations $139,100 810.1550 0.0000 Product Identity and Disclosure of Ingredients (Composition) (Chemical Identity) $300 810.2100 0.0000 Products for hard surfaces -EPA Disinfectant test $9,200 810.2100 0.0000 Products for hard surfaces - AOAC Fungicide test $2,200 810.2100 (b)&(i) Chemical Analysis $6,900 810.2100 (f) Products for hard surfaces - Fungicidal test $2,200 810.2100 (g) Products for hard surfaces - Virucidal activity method $5,600 810.2100 (g) Products for hard surfaces -AOAC Tuberculocidal test $4,500 810.2100 (j) Products for hard surfaces -Sanitizer test non food $5,600 810.2100 (i) Products for hard surfaces - Hard inanimate surface non food $5,600 810.2100 (m)(2) Products for hard surfaces - AOAC Germicidal, detergent sanitizers $4,900 810.2100 b,c,d or i Products for hard surfaces -AOAC use dilution test, germicidal $8,300 810.2100 c,d,e Products for hard surfaces -AOAC Use dilution/germicidal spray/carrier $8,300 810.2200 Products for hard surfaces - AVG $8,100 810.2200 - itemized Limited disinfectant $5,500 810.2200 - itemized Broad spectrum disinfectant $7,500 810.2200 - itemized Hospital disinfectant $7,800 810.2200 - itemized Fungicidal disinfectant $5,500 810.2200 - itemized Virucidal disinfectant $17,000 810.2200 - itemized Tuberculocidal disinfectant $6,100 810.2200 - itemized Additional bacteria $5,300 810.2200 - itemized Non-food contact $6,800 810.2200 - itemized Food contact - Halide products $5,800 810.2200 - itemized Food contact - Non-halide products $7,900 810.2200 - itemized Sanitizers for urinal and toilet bowl water and in-tank sanitizers $7,400 810.2200 - itemized Residual self-sanitizing - wet surfaces $6,800 810.2200 - itemized Sterilants $15,400 810.2300 b Products for fabrics/textiles -EPA Carpet Sanitizer $4,500 810.2400 Products for air sanitizers $7,200 810.2400 (b)(j) Chemical Analysis $200 810.2400 (b)(1) Chemical Analysis $5,600 810.2600 Products for microbial pests associated with human and animal waste $7,400 810.2700 (d) Products for treating water systems AOAC- water disinfectants pools $10,400 810.3000 General considerations for Efficacy of invertebrate control agents $800 810.3100 Soil treatments for imported fire ants $20,100 810.3200 Livestock, poultry,fur and wool bearing animal treatments $209,500 810.3300 Treatments to control pests of human and pets $298,000 810.3400 Mosquito,blackfly and biting midge treatments $58,600 810.3500 Premises Treatments $19,500 810.3600 Structural Treatments $37,700 810.3700 Insect repellants for human skin and outdoor premises $106,000 810.3700 - temized Cage studies with mosquitoes $25,500 810.3700 - temized Cage studies with biting flies $28,300 810.3700 - temized Lab studies with ticks $37,500 810.3700 - temized Field studies with mosquitoes $86,100 810.3700 - temized Field studies with biting flies $86,100 810.3800 0.0000 Methods for efficacy testing of termite baits $78,100 830.1550 Product identity and composition $300 830.1600 Description of materials used to produce the product $400 830.1620 Description of production process $500 830.1650 Description of formulation process $500 830.1670 Discussion of formulation of impurities $500 830.1700 Preliminary analysis $41,000 830.1750 Certified limits $300 830.1800 Enforcement analytical method $21,500 830.1900 Submittal of samples $700 830.6302 Color $1,000 830.6303 Physical state $1,000 830.6304 Odor $1,000 830.6313 Stability to normal and elevated temperatures, metals, and metal ions $11,500 830.6314 Oxidation/reduction: chemical incompatibility $3,900 830.6315 Flammability $2,800 830.6316 Explodability $5,400 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 830.6317 Storage stability $16,000 830.6319 Miscibility $1,500 830.6320 Corrosion characteristics $3,800 830.6321 Dielectric breakdown voltage $3,300 830.7000 PH $1,000 830.7050 UV/visible light absorption $2,800 830.7100 Viscosity $1,900 830.7200 Melting point/melting range $1,700 830.7220 Boiling point/boiling range $2,100 830.7300 Density/relative density/bulk density $1,900 830.7370 Dissociation constants in water $6,300 830.7520 Particle size, fiber length, and diameter distribution $1,900 830.7550 Partition coefficient (n-octanol/water) - shake flask method $8,700 830.7560 Partition coefficient (n-octanol/water) -generator column $9,300 830.7570 Partition coefficient (n-octanol/water) -estimation chromatography $6,100 830.7840 Water Solubility: column elution/shake flask $12,500 830.7860 Water solubility $12,500 830.7950 Vapor pressure $20,900 835.1110 Activated Sludge Sorption Isotherm $24,000 835.1230 Sediment and soil adsorption/desorption $52,000 835.1240 Leaching and adsorption/desorption $71,000 835.1410 Laboratory volatility $34,100 835.2120 Hydrolysis $51,000 835.2210 Direct Photolysis $47,800 835.2240 Photodegradation in water $62,300 835.2370 Photodegradation in air $166,900 835.2410 Soil photolysis $89,900 835.3110 Ready Biodegradability $10,500 835.3180 Freshwater and marine or estuarine environmental expression testing $157,000 835.3220 Porous Pot Test $40,100 835.3300 Soil Persistance and Degradation $156,200 835.4100 Aerobic soil metabolism $131,300 835.4200 Anaerobic soil metabolism $182,600 835.4300 Aerobic aquatic metabolism $124,300 835.4400 Anaerobic aquatic metabolism $707,400 835.6100 Terrestrial field dissipation $442,000 835.6200 Aquatic field dissipation $371,800 835.6300 Forestry dissipation $383,200 835.6400 Combination and tank mixes $598,700 835.7100 Groundwater Monitoring $1,858,600 835.8100 Field volatility $630,600 840.1100 Spray droplet size spectrum $336,800 840.1200 Spray drift field deposition $21,100 850.1000 Use Profile $300 850.1010 Aquatic invertebrate acute toxicity, freshwater daphnids $23,600 850.1020 Gammarid acute toxicity test NA 850.1025 Oyster acute toxicity test $28,000 850.1035 Mysid acute toxicity test $28,000 850.1045 Penaeid acute toxicity test $28,000 850.1055 Bivalve acute tox larval (embryo/larval) $28,000 850.1075 Fish acute toxicity (freshwater) $15,600 850.1075 Fish acute toxicity test (estaurine/marine) $15,100 850.1300 Daphnid chronic toxicity test $164,200 850.1350 Mysid chronic tox - aquatic invertebrate life-cycle (saltwater) $50,500 850.1400 Fish early-life stage toxicity test (freshwater) $51,900 850.1450 Fish early-life stage toxicity test (saltwater) NA 850.1500 Fish life-cycle toxicity $712,900 850.1710 Aquatic Bioavailability/Biomagnification: Oyster BCF $161,300 850.1730 Aquatic Bioavailability/Biomagnification: Fish BCF $182,800 850.1735 Whole sediment acute toxicity invertebrates (freshwater) $26,600 850.1740 Whole sediment acute toxicity invertebrates (marine) $56,900 850.1790 Chironomid sediment toxicity test $112,300 850.1800 Tadpole/sediment subchronic toxicity test $265,000 850.1850 Aquatic food chain transfer - Bioavailability $423,000 850.1900 Generic freshwater microscosm test (laboratory) $399,200 850.1925 Site-specific aquatic microcosm test (laboratory) $338,300 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 850.1950 Simulated or actual field testing - field animal $712,900 850.1950 Simulated or actual field testing - aquatic $834,600 850.1950 Simulated or actual field testing - insect predators $121,700 850.1950 Simulated or actual field testing - plants $86,900 850.2100 Avian acute oral toxicity test $14,000 850.2200 Avian dietary toxicity test $9,000 850.2300 Avian reproduction test $234,000 850.2400 Wild mammal acute toxicity $58,600 850.2500 Simulated or actual field testing terrestrial wildlife $733,100 850.2500 Simulated or actual field testing - birds $834,600 850.3020 Honey bee acute contact toxicity $4,400 850.3030 Honey bee toxicity of residues on foliage $17,400 850.3040 Field testing for pollinators $66,100 850.4000 Background - Nontarget plant testing NA 850.4025 Target area phytotoxicity NA 850.4100 Terrestrial plant toxicity (seedling emergence, Tier I) $22,200 850.4150 Terrestrial plant toxicity (vegetative vigor, Tier I) $22,600 850.4200 Seed germination/root elongation toxicity test $15,600 850.4200 Seed germination $38,800 850.4225 Seedling emergence, Tier II $28,300 850.4230 Early seed growth toxicity test NA 850.4250 Vegetative vigor, Tier II $44,900 850.4300 Terrestrial plants field study, Tier III $53,500 850.4400 Aquatic plant toxicology test using Lemna spp., Tier I $44,200 850.4400 Aquatic plant toxicology test using Lemna spp., Tier II $45,800 850.4450 Aquatic plants field study, Tier III $34,700 850.5100 Soil microbial community toxicity test $17,300 850.5400 Algal Toxicity Tier I and Tier II $17,500 850.6800 Modified activated sludge, respiration inhibition test $5,200 860.1100 Chemical identity $1,700 860.1200 Directions for use $5,600 860.1300 Nature of the residue in plants $139,100 860.1300 Nature of the residue in livestock $147,200 860.1340 Residue analytical method - plants $17,700 860.1340 Residue analytical method - livestock $91,100 860.1360 Multiresidue method $33,400 860.1380 Storage stability data $24,100 860.1400 Water $74,800 860.1400 Irrigated crops (one-crop) $106,400 860.1400 Fish $144,700 860.1460 Food handling $285,200 860.1480 Meat/m ilk/poult ry/eg g s $207,300 860.1500 Crop field trials $101,700 860.1520 Processed food/feed $109,300 860.1540 Reduction of Residues $20,900 860.1550 Proposed tolerance $7,500 860.1560 Reasonable grounds in support of the petition $13,900 860.1650 Submittal of analytical reference standards $400 860.1850 Confined accumulation in rotational crops $325,200 860.1900 Field accumulation in rotational crops $208,600 870.1100 Acute oral toxicity (rat) $4,800 870.1200 Acute dermal toxicity $7,100 870.1300 Acute inhalation toxicity (rat) $34,200 870.1300 Acute inhalation tox (microbials) $16,700 870.2400 Acute eye irritation (rabbit) $2,800 870.2500 Acute dermal irritation $2,800 870.2600 Skin (dermal) sensitization $9,900 870.3100 90-day oral toxicity in rodents $192,100 870.3150 90-day oral toxicity in non-rodents $287,700 870.3200 21/28-day dermal toxicity $126,300 870.3250 90-day dermal toxicity $160,700 870.3355 Combined Chronic Toxicity/Carcinogenicity Testing of Respirable Fibrous Particles (inhalation route) $4,506,600 870.3465 90-day inhalation toxicity (rat) $637,600 870.3700 Prenatal developmental toxicity study (rat) $142,300 870.3700 Prenatal developmental toxicity study (rabbit) $202,600 870.3800 Reproduction and fertility effects (multigeneration) - rat $478,200 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 870.4100 Chronic oral toxicity - dog $921,500 870.4200 Carcinogenicity (microbials) $1,401,900 870.4200 Carcinogenicity (rat and mouse, preferred) $1,963,100 870.5100 Bacterial reverse mutation assay $6,500 870.5300 In vitro mammalian cell gene mutation test $29,100 870.5375 In vitro mammalian chromosomal aberration test $35,000 870.5380 Mammalian spermatogonia! chromosomal aberration test $27,000 870.5385 Mammalian bone marrow chromosomal aberration test $41,700 870.5395 Mammalian erthrocyte micronucleus test $28,600 870.5450 Rodent dominant lethal assay NA 870.5500 Bacterial DNA damage or repair tests NA 870.5550 Unscheduled DNA synthesis in mammalian cells in culture $31,300 870.6100 Acute and 28 day delayed neurotoxicity organophosphorus substances (hen) $120,400 870.6200 90-day Neurotoxicity (rat) $279,200 870.6200 Acute neurotoxicity (rat) $189,200 870.6300 Developmental neurotoxicity study $854,100 870.6500 Schedule-controlled operant behavior $248,800 870.6850 Peripheral nerve function $166,900 870.6855 Neurophysiology: sensory evoked potentials $166,900 870.7200 Companion animal safety $236,700 870.7485 Metabolism and pharmacokinetics $237,800 870.7600 Dermal penetration $192,000 870.7800 Immunotoxicity $78,800 875.1100 Dermal outdoor exposure $233,500 875.1200 Dermal indoor exposure $175,900 875.1300 Inhalation outdoor exposure (HRSB costs not included) $547,100 875.1400 Inhalation indoor exposure $175,900 875.1500 Biological monitoring $262,000 875.1600 Application exposure data reporting and calculations $11,400 875.1700 Product use information $4,200 875.2100 Dislodgeable foliar residue dissipation and turf transferable residues $83,600 875.2200 Soil residue dissipation $308,500 875.2300 Indoor surface residue dissipation $91,700 875.2400 Dermal exposure $190,400 875.2500 Inhalation exposure $110,800 875.2600 Biological monitoring (HRSB costs not included) $455,900 875.2700 Product use information $4,600 875.2800 Description of human activity $4,600 875.2900 Data reporting and calculations $4,600 875.3000 Nondietary ingestion exposure $113,800 880.1100 Product identity $300 880.1200 Description materials, production, formulation $1,300 880.1400 Discussion of formation of impurities $500 880.3800 Immune Response $118,200 880.4350 Non-target insect testing $20,900 880.4425 Dispenser - water leaching $34,800 885.1100 Product Identity $7,000 885.1200 a Manufacturing process $4,900 885.1200 b Deposition of samples $4,900 885.1300 Discussion of formulation of unintentional ingredients $4,900 885.1400 Analysis of samples $103,600 885.1500 Certification of limits $500 885.2000 Background for residue analysis of microbial pest control agents NA 885.2100 Chemical identity $900 885.2200 Nature of the residue in plants $150,700 885.2250 Nature of the residue in animals $163,000 885.2300 Analytical method - plants $36,900 885.2350 Analytical method - animals $61,100 885.2400 Storage stability, plants $43,100 885.2500 Magnitude of residue in plants $190,800 885.2550 Magnitude of residue in meat/milk/poultry $219,300 885.2600 Magnitude of residue in potable water, fish, and irrigated crops $308,000 885.3000 Background Mammalian Infectivity/pathogenicity analysis $347,800 885.3050 Acute oral toxicity/pathogenicity $45,900 885.3150 Acute pulmonary toxicity/pathogenicity $52,200 885.3200 Acute injection toxicity/pathogenicity (intravenous) $52,200 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 885.3200 Acute injection toxicity/pathogenicity (intraperitoneal) $17,400 885.3400 Hypersensitivity incidents $1,100 885.3500 Cell Culture $41,700 885.3550 Acute toxicity, Tl $29,900 885.3600 Subchronic toxicity/pathogenicity $208,700 885.3650 Reproductive/fertility effects $100,900 885.4050 Avian Oral, Tl $20,900 885.4100 Avian Inhalation toxicity/pathogenicity, Tl $22,300 885.4150 Wild mammal toxicity/pathogenicity,Tl $90,400 885.4200 Freshwater fish toxicity/pathogenicity,Tl $52,200 885.4240 Freshwater invertebrate toxicity/pathogenicity,Tl $52,200 885.4280 Estuarine/marine animal testing, Tl $55,600 885.4280 Estuarine/marine invertebrate testing,Tl $55,600 885.4300 Nontarget plant studies, Tl $46,500 885.4340 Nontarget insect testing, Tier I $14,600 885.4340 Non-target Lepidoptera $46,900 885.4350 Beneficial soil invertebrate testing - Collembola $16,000 885.4380 Honey bee testing $15,100 885.4600 Avian chronic pathogenicity and reproduction, Till $243,400 885.4650 Aquatic invertebrate range testing,Till $35,500 885.4700 Fish life cycle studies,Till $347,800 885.4750 Aquatic ecosystem test $486,900 885.5200 Terrestrial environmental expression tests $132,100 885.5300 Freshwater environmental expression test NA 885.5400 Marine or estaurine environmental expression tests $132,100 NA OECD unique identifier for transformation event $400 NA Appropriate identifier for active and inert ingredient(s) (e.g., name or designation ) $300 NA Identification of transformation event and PIP ingredients (combination of OECD unique identifier for transformation event and Appropriate identifier for active and inert inqredient(s)) $700 NA Biology of the plant $3,900 NA Biology of the plant $20,500 NA Description of the intended trait $300 NA Expression level in plant $387,200 NA Characterization of protein (active/inert) $97,700 NA • Spectrum of pesticidal activity • Mode of action • Characterization of expressed substance(s) (molecular characterization data) (combination of Description of the intended trait, Expression level in plant, and Characterization of protein (active/inert)) $161,800 NA Transformation system $1,100 NA Certification of limits $300 NA Analytical detection method $80,500 NA Submittal of samples $600 NA Characterization of inserted DNA $2,300 NA Inheritance and stability $300 NA Characterization of inserted DNA (combination of Characterization of inserted DNA & Inheritance and stability) $2,600 NA Surrogate protein production $27,900 NA Acute oral toxicity $55,300 NA Toxicity of substances other than proteins NA NA Protein Digestion via Kinetic Enzyme $153,700 NA Quantified concentration of protein produced in various tissues, e.g., leaf, seed, fruit, pollen, and whole plant by Western blot or ELISA $68,800 NA Laboratory and/or greenhouse testing to determine sexual compatibility/ability to form a viable hybrid between the modified crop plant and wild or weedy relatives in the United States. Testing would begin with the most closely related species in the same family that occur in the area of cultivation. $101,500 NA Description of propensity of the crop plant to naturalize, including extent of existing feral populations (In most cases, sufficient information can be obtained from literature searches and/or consultations with breeders. Field surveys may be required in some instances.) $20,300 NA Outcrossing potential - information on potential outcrossing with all wild or weedy relatives with which the transformed plant can form viable hybrids in nature, e.g., degree of sexual compatibility, degree of overlap in the geographic distribution of relatives and crop cultivation areas, phenology assessment. (Information can be based upon literature, field experts, breeders, etc.) $4,700 NA Reproductive timing and output, e.g., timing of flowering and seed set and amount of seed produced; for root crops including also size, mass, and shape of tubers at harvest time. Stability of the acquired transgene in the hybrids and their proqenv. $28,100 NA Studies to evaluate the potential impact of transgene introgression, for example: • plant community dynamics modeling (with hybrids and plants expected in the communities in which the hybrids exist). • plant competition growth chamber studies, e.g., series replacement under controlled conditions. • plant competition mesocosm studies (with hybrids and plants expected in the communities in which the hybrids exist). • field studies, e.q., to investiqate impact of virus infection on wild or weedv relatives of the modified plant. $2,029,800 NA Bioinformatic amino acid sequence comparison of short contiguous amino acid segments using an allergen database to identify anv allerqens containinq identical short sequences. $10,100 NA Bioinformatic amino acid sequence search for overall similarity with known toxins and allergens. $8,100 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 NA Bioinformatic amino acid sequence analysis (comparison to toxins) (also called a global amino acide sequence comparison $4,300 NA In vitro digestibility in simulated gastric fluid and simulated intestinal fluid (as defined in the U.S. Pharmacopeia). $47,400 NA Assessment of heat stability/lability. $37,200 NA Allergenicity Information: specific serum-binding study $143,200 NA Allergencity Info: in vitro digestibility in SGF $43,000 NA Allergenicity Info: Assessment of heat stability/lability $33,800 NA Allergenicity Info: Bioinformatic amino acid sequence analysis (comparison to allergens) $4,400 NA Toxicity and Allergenicity info: in vitro digestibility in SIF $43,000 NA Allergenicity analysis (combination of in vitro digestibility in SGF, Assessment of heat stability/lability, Bioinformatic amino acid sequence analysis (comparison to allergens), and in vitro digestibility in SIF) $124,200 NA 90-day oral toxicity $169,800 NA Specific serum binding test $135,200 NA Hypersensitivity incidents $1,000 NA Wild mammal oral toxicity $55,300 NA Avian single-dose oral LD50 $12,400 NA Avian oral toxicity (note: the cost of this is equivalent to two avian single-dose LD50s) $24,800 NA Avian dietary toxicity $8,000 NA Freshwater fish oral toxicity $14,700 NA Freshwater invertebrate testing (aka Freshwater invertebrate - toxicity) $46,100 NA Estuarine and marine animal toxicity $49,200 NA Honey bee testing - Apis mellifera (larvae) $35,700 NA Honey bee testing - Apis mellifera (adult) $14,300 NA Nontarget insect testing- Ladybird beetles $18,300 NA Nontarget insect testing- Parasitic Hymenoptera $18,300 NA Nontarget insect testing- Predaceous Neuropteran $18,300 NA Nontarget insect testing - Lepidoptera $18,300 NA Nontarget insect testing - Predaceous Hemiptera $18,300 NA Non-Target Hemiptera Study $49,200 NA Non-target insect testing - Coleoptera $18,300 NA Arthropod - toxicity (combination of all nontarget insect testing tests) $55,000 NA Non-target Arthropod Study (3 species) $147,500 NA Beneficial soil invertebrate testing- Collembola $15,100 NA Beneficial soil invertebrate testing- Earthworm $15,100 NA Nonarthropod invertebrate - toxicity (for a single species) (combination of Beneficial soil invertebrate testing for Collembola and Earthworms) $15,100 NA Nontarget plant studies (aka plant studies) $44,000 NA Soil microbial community toxicity test $16,300 NA Tritrophic testing of selected beneficial insects $112,500 NA Tritrophic Testing of Selected Beneficial Insects $364,800 NA Protein synthesis inhibition study $157,000 NA Lack of association of proteins in solution $4,400 NA Plant tissue testing $5,200 NA Plant tissue testing (reflected in NTO data costs) $31,800 NA Endangered species exposure determination $80,800 NA Semi-field studies $409,000 NA Semi-field Study on Honey Bees $141,300 NA Degradation rate in the environment $418,000 NA Field persistence $115,800 NA Environmental Fate - Field Persistence $1,519,800 NA Field studies $260,300 NA Additive effects - synergy study $29,900 NA Potential for vertical gene flow $68,300 NA Potential for horizontal gene transfer $44,000 NA Potential for horizontal gene transfer (lab estimate) $6,800 NA Evaluation of environmental impacts of gene flow between sexually compatible plants $123,500 NA Potential for weediness $235,900 NA Evaluation of potential weediness $0 NA Target pest biology and ecology $16,900 NA Target organism biology and ecology $494,800 NA Target organism susceptibility - above ground target $400,800 NA Target organism susceptibility - below ground target $290,400 NA Dose expression for the target pests $462,300 NA Potential for cross resistance $25,100 NA Potential for cross resistance $307,900 NA Simulation models to predict PIP durability and evaluate resistance management options $91,100 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field $94,200 ------- Test Guideline Guideline Section or NA* Test Name Average Test Cost Adjusted for Inflation to 2021 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field $1,239,000 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field - Plan Development Cost $696,800 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field - Implementation Monitoring, Reporting $95,700 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field - Bioassavs $399,300 NA Development and implementation of a resistance monitoring plan to detect potential resistance to the PIP in the field - Annual Reporting $70,700 NA Resistance monitoring plan $1,847,700 NA Development of a remedial action plan to mitigate potential resistance to the PIP in the field $12,600 NA Development of a refuge compliance plan $5,000 NA Development of a grower education program $520,600 NA Annual reporting $81,600 NA Independent lab validation of an analytical method $20,900 NA If an analytical method for residue exists - analytical method for soil and/or water $18,400 NA If an analytical method for residue exists - independent lab validation of the completed analytical methods $20,900 NA Human Subjects Review Board Costs $32,300 Source: EPA Estimates, adjusted for inflation using the BLS May 2018 National Occupational Employment and Wage Estimates wage rate for occupation code 19-0000 ------- |