United States Prevention, Pesticides EPA 738-R-04-012
Environmental Protection and Toxic Substances September 2004
Agency (7508C)
Reregistration
Eligibility Decision for
Thiram
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UNITEDSTATESENVIRONMENTALPROTECTION AGENCY
WASHINGTON, D.C. 20460
OFFICE OF
PREVENTION, PESTICIDES
AND TOXIC SUBSTANCES
CI .RT11< I El) MAII
Dear Registrant:
This is to inform you that the Environmental Protection Agency (hereafter referred to as EPA or
the Agency) has completed its review of the available data and public comments received related to the
preliminary risk assessments for the fungicide thiram. The enclosed Reregistration Eligibility Decision
(RED) document was approved on September 30, 2004. Public comments and additional data received
were considered in this decision.
Based on its review, EPA has identified risk mitigation measures that the Agency believes are
necessary to address the environmental risks associated with the current use of thiram. EPA is now
publishing its Reregistration Eligibility Decision (RED) and risk management decision for thiram and its
associated human health and environmental risks.
The RED and supporting risk assessments for thiram are available to the public in EPA's
Pesticide Docket OPP-2004-0183 at: www, epa. gov.edockets. In addition, the Thiram RED may be
downloaded or viewed at: www.epa.gov/pesticides/reregistration/status.htm. Earlier information on
thiram, including public comments, can be found under docket OPP-2003-0287.
The Thiram RED was developed through EPA's public participation process, published in the
Federal Register on May 14, 2004, which provides opportunities for public involvement in the Agency's
pesticide tolerance reassessment and reregistration programs. Developed in partnership with USD A and
with input from EPA's advisory committees and others, the public participation process encourages
robust public involvement starting early and continuing throughout the pesticide risk assessment and
risk mitigation decision making process. The public participation process encompasses full, modified,
and streamlined versions that enable the Agency to tailor the level of review to the level of refinement of
the risk assessments, as well as to the amount of use, risk, public concern, and complexity associated
with each pesticide. Using the public participation process, EPA is attaining its strong commitment to
both involve the public and meet statutory deadlines.
Please note that the thiram risk assessment and the attached RED document concern only this
particular pesticide. This RED presents the Agency's conclusions on the dietary, drinking water,
occupational and ecological risks posed by exposure to thiram alone. This document also contains both
generic and product-specific data that the Agency intends to require in Data Call-Ins (DCIs). Note that
DCIs, with all pertinent instructions, will be sent to registrants at a later date. Additionally, for product-
specific DCIs, the first set of required responses will be due 90 days from the receipt of the DCI letter.
The second set of required responses will be due eight months from the receipt of the DCI letter.
As part of the RED, the Agency has determined that thiram will be eligible for reregistration
provided that all the conditions identified in this document are satisfied, including implementation of the
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risk mitigation measures outlined in Section IV of the document. Sections IV and V of this RED
document describe labeling amendments for end-use products and data requirements necessary to
implement these mitigation measures. Instructions for registrants on submitting the revised labeling can
be found in the set of instructions for product-specific data that accompanies this document.
Should a registrant fail to implement any of the risk mitigation measures outlined in this
document, the Agency will continue to have concerns about the risks posed by thiram. Where the
Agency has identified any unreasonable adverse effect to human health and the environment, the
Agency may at any time initiate appropriate regulatory action to address this concern. At that time, any
affected person(s) may challenge the Agency's action.
If you have questions on this document or the label changes necessary for reregistration, please
contact the Chemical Review Manager, Craig Doty, at (703) 308-0112. For questions about product
reregistration and/or the Product DCI that accompanies this document, please contact Venus Eagle at
(703)308-8045.
Sincerely,
Debra Edwards, Ph.D.
Director, Special Review and
Reregistration Division
Attachment
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REREGISTRATION ELIGIBILITY
DECISION
for
Thiram
List A
CASE 0122
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TABLE OF CONTENTS
Thiram TEAM i
EXECUTIVE SUMMARY v
I. Introduction 1
II. Chemical Overview 2
A. Regulatory History 2
B. Chemical Identification 2
C. Use Profile 3
D. Estimated Usage of Thiram 5
III. Summary of Thiram Risk Assessment 6
A. Human Health Risk Assessment 6
1. Dietary Risk from Food 6
a. Toxicity and Carcinogenicity 6
b. FQPA Safety Factor 7
c. Population Adjusted Dose (PAD) & Reference Dose (RfD) 8
d. Exposure Assumptions 10
e. Acute Dietary (Food) Risk 11
f. Chronic Dietary (Food) Risk 12
g. Cancer Dietary Risk Assessment 12
2. Dietary Risk from Drinking Water 12
a. Surface Water 13
b. Groundwater 13
3. Residential Risk 14
a. Aggregate Risk 15
4. Occupational Risk 15
a. Toxicity 16
b. Occupational Risk Assessment 16
c. Incident Reports 20
B. Environmental Risk Assessment 20
1. Environmental Fate and Transport 20
2. Ecological Effects (Toxicity) Assessment 21
3. Ecological Risk Calculations 23
4. Ecological Risk Profile 24
a. Risk to Birds 24
b. Risk to Mammals 26
c. Risk to Aquatic Animals 27
d. Risk to Aquatic Plants 29
e. Risk to Endangered Species 30
IV. Risk Management, Reregistration, and Tolerance Reassessment Decision 35
A. Determination of Reregistration Eligibility 35
B. Public Comments and Responses 35
C. Regulatory Position 35
1. Food Quality Protection Act Findings 35
a. Determination of Safety to U.S. Population 36
b. Determination of Safety to Infants and Children 36
c. Endocrine Disruptor Effects 38
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d. Cumulative Risks 38
2. Tolerance Summary 38
a. Tolerances Currently Listed Under 40 CFR §180.301 38
b. Codex Harmonization 39
D. Regulatory Rationale 39
1. Human Health Risk Management 40
a. Dietary (Food) Risk Mitigation 40
b. Drinking Water Risk Mitigation 40
c. Residential Risk Mitigation 40
d. Occupational Risk Mitigation 44
2. Environmental Risk Mitigation 45
3. Other Labeling Requirements 44
4. Endangered Species Considerations 45
a. The Endangered Species Program 45
b. General Risk Mitigation 45
c. Species-Specific Risk Mitigation 45
d. Endangered Species Determination 46
V. What Registrants Need to Do 47
A. Manufacturing Use Products 48
1. Additional Generic Data Requirements 48
2. Labeling for Technical and Manufacturing-Use Products 49
B. End-Use Products 50
1. Additional Product-Specific Data Requirements 50
2. Labeling for End-Use Products 50
a. Label Changes Summary Table 51
VI. Appendicies 65
Appendix A. Use Patterns Subject to Reregistration for Thiram (Case 2030) 67
Appendix B. Data Supporting Guideline Requirements for the Reregistration 99
of Thiram
Appendix C. Technical Support Documents 109
Appendix D. Citations Considered to Be Part of the Data Base Supporting the
Reregistration Decision (Bibliography) Ill
Appendix E. Generic Data Call-In 225
Appendix F. Product Specific Data Call-In 239
Appendix G. EPA's Batching of Thiram Products for Meeting Acute Toxicity Data
Requirements for Reregistration 249
Appendix H. List of Registrants Sent this Data Call-In 255
Appendix I. List of Available Related Documents and Electronically Available Forms 257
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Thiram TEAM
Office of Pesticide Programs
Biological and Economic Analysis Assessment
Richard Michell Herbicide and Insecticide Branch
William Phillips Herbicide and Insecticide Branch
Jin Kim Economic Analysis Branch
Health Effects Risk Assessment
Felicia Fort Reregistration Branch 1
Jeff Dawson Reregistration Branch 1
Elizabeth Mendez Reregistration Branch 1
Timothy Dole Reregistration Branch 1
Environmental Fate Risk Assessment
Fred Jenkins Environmental Risk Branch 2
William Eckel Environmental Risk Branch 2
James Carleton Environmental Risk Branch 2
Field and External Affairs Division
Cara Dzubow Endangered Species Program
Reregistration Support
Craig Doty Special Review Branch
Meghan French Special Review Branch
Anne Overstreet Special Review Branch
Venus Eagle Product Reregistration Branch
Registration Support
Cynthia Giles-Parker Fungicide Branch
Daniel Peacock Insecticide/Rodenticide Branch
Bryant Crowe Herbicide Branch
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GLOSSARY OF TERMS AND ABBREVIATIONS
a.i. Active Ingredient
aPAD Acute Population Adjusted Dose
APHIS Animal and Plant Health Inspection Service
ARTF Agricultural Re-entry Task Force
BCF Bioconcentration Factor
CDC Centers for Disease Control
CDPR California Department of Pesticide Regulation
CFR Code of Federal Regulations
CliF.T Cholinesterase Inhibition
CMBS Carbamate Market Basket Survey
cPAD Chronic Population Adjusted Dose
CSFIIUSDA Continuing Surveys for Food Intake by Individuals
CWS Community Water System
DCI Data Call-In
DEEM Dietary Exposure Evaluation Model
DL Double layer clothing {i.e., coveralls over SL}
DWLOC Drinking Water Level of Comparison
EC Emulsifiable Concentrate Formulation
EDSP Endocrine Disruptor Screening Program
EDSTAC Endocrine Disruptor Screening and Testing Advisory Committee
EEC Estimated Environmental Concentration. The estimated pesticide concentration in an environment, such
as a terrestrial ecosystem.
EP End-Use Product
EPA U.S. Environmental Protection Agency
EXAMS Tier II Surface Water Computer Model
FDA Food and Drug Administration
FFDCA Federal Food, Drug, and Cosmetic Act
FIFRA Federal Insecticide, Fungicide, and Rodenticide Act
FOB Functional Observation Battery
FQPA Food Quality Protection Act
FR Federal Register
GL With gloves
GPS Global Positioning System
HIARC Hazard Identification Assessment Review Committee
IDFS Incident Data System
IGR Insect Growth Regulator
IPM Integrated Pest Management
RED Reregistration Eligibility Decision
LADD Lifetime Average Daily Dose
LC50 Median Lethal Concentration. Statistically derived concentration of a substance expected to causing
death in 50% of test animals, usually expressed as the weight of substance per weight or volume of water,
air or feed, e.g., mg/1, mg/kg or ppm.
LCO Lawn Care Operator
LD50 Median Lethal Dose. Statistically derived single dose causing death in 50% of the test animals when
administered by the route indicated (oral, dermal, inhalation), expressed as a weight of substance per unit
weight of animal, e.g., mg/kg.
LOAEC Lowest Observed Adverse Effect Concentration
LOAEL Lowest Observed Adverse Effect Level
LOC Level of Concern
LOEC Lowest Observed Effect Concentration
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mg/kg/day Milligram Per Kilogram Per Day
MOE Margin of Exposure
MP Manufacturing-Use Product
MRID Master Record Identification (number). EPA's system of recording and tracking studies submitted.
MRL Maximum Residue Level
N/A Not Applicable
NASS National Agricultural Statistical Service
NAWQA USGS National Water Quality Assessment
NG No Gloves
NMFS National Marine Fisheries Service
NOAEC No Observed Adverse Effect Concentration
NOAEL No Observed Adverse Effect Level
NPIC National Pesticide Information Center
NR No respirator
OP Organophosphorus
OPP EPA Office of Pesticide Programs
ORETF Outdoor Residential Exposure Task Force
PAD Population Adjusted Dose
PCA Percent Crop Area
PDCI Product Specific Data Call-In
PDP USDA Pesticide Data Program
PF10 Protections factor 10 respirator
PF5 Protection factor 5 respirator
PHED Pesticide Handler's Exposure Data
PHI Preharvest Interval
ppb Parts Per Billion
PPE Personal Protective Equipment
PRZM Pesticide Root Zone Model
RBC Red Blood Cell
RED Reregistration Eligibility Decision
REI Restricted Entry Interval
RfD Reference Dose
RPA Reasonable and Prudent Alternatives
RPM Reasonable and Prudent Measures
RQ Risk Quotient
RTU (Ready-to-use)
RUP Restricted Use Pesticide
SCI-GROWTier I Ground Water Computer Model
SF Safety Factor
SL Single layer clothing
SLN Special Local Need (Registrations Under Section 24(c) of FIFRA)
STORET Storage and Retrieval
TEP Typical End-Use Product
TGAI Technical Grade Active Ingredient
TRAC Tolerance Reassessment Advisory Committee
TTRS Transferable Turf Residues
UF Uncertainty Factor
USDA United States Department of Agriculture
USFWS United States Fish and Wildlife Service
USGS United States Geological Survey
WPS Worker Protection Standard
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EXECUTIVE SUMMARY
The Environmental Protection Agency (EPA or the Agency) has completed its review of public
comments on the human health and environmental risk assessments for thiram and is issuing its risk
management decision. EPA has concluded that thiram is eligible for reregistration provided that the
registrants implement the actions and mitigation measures outlined in this document. Thiram is a
member of the dithiocarbamate class of non-systemic fungicides. It is used as a fungicide to prevent
crop damage in the field and to protect harvested crops (apples, peaches, and strawberries) from
deterioration in storage or transport. It is also used as a seed protectant (e.g. small seeded vegetables,
large seeded vegetables, cereal grains and other seeds, coniferous seeds, cotton seed, ornamental seeds,
and soybeans) and to protect turf from fungal diseases. In addition, thiram is used as an animal repellent
to protect crops from damage by rabbits, rodents, and deer. Thiram acts by concomitant inhibition of
spore germination and mycelial growth through multi-site interference of enzyme processes associated
with respiration. As an animal repellent, it creates a taste aversion to deter feeding. It is available in a
variety of formulations including dust, wettable powder, water dispersable granule, flowable
concentrate, dry flowable, soluble concentrate, and ready-to-use liquid. Thiram is applied both by
commercial seed treaters and on-farm applicators. Tolerances for residues in/on food and feed
commodities are currently expressed in terms of residues of thiram (CFR §180.132) per se and are
established at 7 ppm for apples, peaches, and strawberries. Seed treatments are considered to be non-
food uses and therefore do not require a tolerance.
Based on available data, an estimated 165,000 pounds of thiram are applied to 35,000 acres of
strawberries, apples, and peaches annually. Thiram usage on strawberries and apples accounts for
nearly all of this usage. Up to 631,000 pounds of thiram are used to treat approximately 1.3 billion
pounds of seed annually.
Overall Risk and Mitigation Summary
An aggregate risk assessment looks at the combined risk from dietary exposure (food and drinking
water pathways) as well as exposures from non-occupational sources (e.g., residential uses). Drinking
water exposure to pesticides can occur through ground water and surface water contamination. In
assessing drinking water risks, EPA considers acute (one day), chronic (long-term) and cancer exposure,
and uses either modeling or monitoring data if available, to estimate those risks. To determine the
maximum contribution from water allowed in the diet, EPA first looks at how much of the overall
allowable risk is contributed by food and then calculates a "drinking water level of comparison"
(DWLOC) to determine whether modeled or monitoring exposure estimates exceed the allowable risk
level. Estimated environmental concentrations (EECs) that are above the corresponding DWLOC
exceed the Agency's level of concern.
Acute Aggregate Risk. Acute risks from aggregate exposures are not of concern, due to removal
of strawberries from the label, a voluntary request for cancellation of apple uses, and requests for
voluntary cancellation of most residential uses. Models have been used to estimate ground and surface
water concentrations. The DWLOCs calculated to assess the surface water contribution to acute
(noncancer) dietary exposure range from 1750wg/L (for the U.S. general population) to less than
500wg/L (infants and children). The surface water EEC (47.8ppb) is significantly less than the acute
DWLOC. The groundwater EEC (0.84) is also significantly less than the acute DWLOC. These
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DWLOCs were calculated assuming no exposure from food in order to evaluate potential acute risk
posed by drinking water alone. However, if dietary exposure due to peach consumption (the only
remaining food use) had been included in the DWLOC calculations, the LOCs would have been only
approximately 10% lower, i.e., the lowest DWLOC would have been 450wg/L. Thus, the Agency
concludes with reasonable certainty that aggregate exposure to food and drinking water will not result in
an unacceptable acute risk.
Short-term Aggregate Risk. Short-term aggregate risks are not of concern. DWLOCs were
calculated based upon average food residues and the residential post-application exposure
scenario(adult golfers). Because the inputs to calculate short-term aggregate risks are very low
(cPAD=2.8% and the MOE at day 0 for golfers is 794), the Agency concludes with reasonable certainty
that aggregate exposure to food, drinking water and residential exposures will not result in an
unacceptable risk.
Chronic Aggregate Risk. Chronic risks from aggregate exposures are not of concern. The
DWLOC calculated to assess the surface water contribution to chronic (noncancer) dietary exposure is a
range from 48.30wg/L (for the U.S. general population) to less than 10.80wg/L (infants and children).
The surface water EEC (4.3 ppb) is less than the chronic DWLOC, indicating that chronic exposure to
thiram in food and drinking water from surface water sources is below the Agency's level of concern.
The groundwater EEC (0.84 ppb) is also less than the chronic DWLOC, indicating that chronic
exposure to thiram in food and drinking water from groundwater sources is below the Agency's level of
concern. Since the model-based estimates for concentrations in surface water and groundwater are
below the calculated chronic DWLOC, the Agency concludes with reasonable certainty that aggregate
exposure to food and drinking water will not result in an unacceptable chronic risk. The Agency's
human heath risk assessment indicates no risks of concern.
Residential Risk. Thiram will no longer be available for sale or use by homeowner applicators.
As such, all residential risks were calculated related to the non-residential turf uses that include golfing
for adults and toddler exposures in areas that can be treated with thiram by certified pesticide
applicators. MOEs for golfers are not of concern to the Agency (MOE=764 at Day 0), and therefore no
risk mitigation measures are required to address this scenario.
To protect children from scenarios of concern (MOE= 4) for exposure to thiram treated turf) and
to further protect from exposure to ornamentals treated with thiram as a deer repellent, the Agency is
requiring the following label modifications:
Deer Repellent Use:
Use one quart of this product in 3 to 7 gallons of water for application to 1000ft2
Applications to ornamentals will be restricted to the following 17 Northern states and
applications will occur during the winter season only (October thru March): OH, PA,
NY, MI, CT, MA, IN, IL, NJ, WV, MN, WI, VT, NH, RI, DE, and MD.
Cancellations of Turf/Other Uses:
Turf applications to parks, athletic fields and commercial landscapes.
All turf applications for turf grown for sale or other commercial use such as sod.
All homeowner and retail uses on residential lawns and turf
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Residential homeowner use as a fungicide on bulbs, flower seeds, greenhouse and nursery
cuttings, and pruning paints.
Through these label amendments and voluntary cancellations to remove all homeowner uses from
Taminco, the Agency believes exposure to the deer repellent use will be insignificant and therefore not
of concern. No additional mitigation is necessary
Occupational Risk The Agency calculated the potential exposure and risk to pesticide
handlers from 28 major occupational exposure scenarios based on the types of equipment and
techniques that potentially can be used for thiram applications. Worker risk is measured by a Margin of
Exposure (MOE) which determines how close the occupational exposure comes to the No-Observed-
Adverse-Effect-Level (NOAEL) taken from an animal study. A MOE of 100 or greater, for both the
dermal and inhalation route is considered to be protective for thiram. Only short- and intermediate-term
exposures are expected and assessed based on label directed use patterns. For occupational handlers,
MOEs are greater than or equal to 100 at some level of protection for most scenarios. Current thiram
labels typically require that handlers wear long pants, long-sleeved shirts, and gloves. Respirators are
generally not required.
Occupational exposure and risk estimates were conducted using maximum application rates and
high-end assumptions for amount of seed treated and planted. A target Margin of Exposure (MOE) of
100 is considered adequate for occupational exposure via dermal and inhalation routes. The results of
the worker exposure assessment indicate that most potential exposure scenarios result in MOEs > the
target MOE of 100 for dermal and inhalation for all of the seed crops treated with thiram products being
actively sold in the U.S.
In most scenarios, MOEs meet or exceed the required target MOE of 100 at some level of
personal protection. For the most part, current label requirements (for personal protection single layer
clothing, gloves, and no respirator) appear to be generally adequate. Scenarios where MOEs do not
exceed 100 at any level of personal protection include some loading scenarios for aerial applications,
aerial granular applications and an on-farm seed treatment of peanuts. To reduce worker exposure, the
Agency has determined that the following measures for specific scenarios are appropriate and required
for reregistration eligibility.
Comply with label changes with updated Worker Protection Standard and other regulations.
Cancellation of the aerial and hand/spoon applications of granular formulations.
Require water soluble bags be instituted for all wettable powder formulations.
Cancellation of on-farm seed treatment for peanuts.
Workers can also be exposed to thiram residues by entering previously treated areas to perform
activities. The Restricted Entry Interval (REI) is used by the Agency to manage risks for
postapplication workers doing activities that require contact with treated surfaces. The REI is the
amount of time required after application before residues decline to a level so entry into the treated area
and engaging in any task or activity would not result in exposures which are of concern. Current labels
for thiram specify an REI of 24 hours. Risks were calculated based on a scenario approach for low
berry (e.g., strawberries), trees/fruit, deciduous (e.g., apples, peaches), and turf/sod (e.g., golf courses,
sod farms). Current REIs are protective for most crops, however risks for reentry workers are of
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concern for very high exposure activities. The number of days required for MOEs to reach the
Agency's level of concern MOE of 100 is 6 to 7 days for apple thinning and 2 days for peach thinning
on the East coast. Risks are a concern for high exposure activities such as transplanting and hand
weeding sod (MOEs>100 at 12-21 days). The Agency is not concerned with maintaining the current
REI of 24 hours because the MOE for peaches is 94. The following mitigation addresses the risks of
concern for high exposure activities associated with apples and sod:
Cancellation of all turf applications for turf grown for sale or other commercial use such as
sod.
Cancellation of all apple uses.
Ecological Risk. The ecological risk assessment for birds shows risks for reproductive effects to
birds. The chronic risk quotients (RQs) for birds including endangered species that exceed levels of
concern (LOCs) range from 26 to 1,237. There is a chronic effect to mammals including endangered
species, which results in RQs that range from 3.9 to 6,250. Acute RQs for fish and aquatic invertebrates
including endangered species range from 0.1 to 28. The Agency's assessment suggested that a number
of endangered species may potentially be impacted by thiram; however, this RED includes only risk
mitigation for the Attwater's Prairie Chicken (Tympanuchus cupido attwateri). The following
mitigation measures address the Agency's ecological risks of concern:
Turf
Cancellation of turf applications to parks, athletic fields, and commercial landscapes.
Cancellation of all homeowner and retail uses on residential lawns and turf.
Cancellation of all turf applications for turf grown for sale or other commercial use such as
sod.
Restrict use to golf course tees and greens only.
Reduce winter golf course treatment from maximum of four applications to maximum of
one single application.
Reduce summer golf course treatment from maximum of eight applications to maximum of
three applications.
Restrict total annual application of thiram to golf courses to 47 pounds active ingredient per
acre.
Increase retreatment interval from seven to 14 days.
Apples
Cancellation of all apple uses.
Strawberries
In California, limit maximum number of applications to five at 2.6 lbs. a.i./A. East of the
Mississippi, limit maximum number of applications to twelve at 2.6 lbs. a.i./A. Label
statement to indicate that 1.3 lbs. a.i./A should be used when thiram is used in
combination with other fungicides.
Establish a 25-foot vegetation buffer zone from water bodies.
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Seed
Planting Depth Restriction: A specification of 1 inch minimum planting depth for cotton,
wheat, barley, oats and sugar beet seed.
To be eligible for reregistation the following language must be added to the label and bag
tags:
"ENVIRONMENTAL HAZARDS: Treated seed are hazardous to birds and mammals. Do not
plant treated seed by broadcasting to the soil surface. Insure that all planted seed are thoroughly
covered with soil, especially in turn areas. Plant cotton, wheat, barley, oats and sugar beet seed a
minimum of 1 inch deep. If seed are not thoroughly incorporated by the planter during planting,
additional incorporation may be required to reduce exposed seed. Clean-up, bury or cover all
spilled seed with soil."
Cotton Use Rate Reduction: Reduce the maximum treating rate for cotton seed from 2.25
oz. ai/cwt (1406 ppm) when treated with thiram as a single active ingredient to 1.6 oz.
ai/cwt (1,000 ppm). Reduce the maximum treating rate for cotton seed for thiram in
products containing multiple active ingredients to 1.0 oz. active thiram/cwt (625 ppm
thiram).
"This pesticide is toxic to fish. Do not apply to water, to areas where surface water is
present, or to intertidal areas below the mean high water mark. Do not contaminate
water when disposing of equipment washwater or rinsate or by disposal of wastes.
Treated seed exposed on soil surface may be hazardous to birds. Cover or collect
spilled seeds."
"This bag contains seed treated with thiram. This product may have effects on federally
listed threatened or endangered species or their critical habitat in some counties. It is a
violation of federal law to kill, harm or harass listed animal species without
authorization. To limit the potential for such impacts when using this product, consult
and follow the instructions provided in the EPA Endangered Species Bulletin for the
County or Parish in which you are applying the seed. To determine whether your
County or Parish has a Bulletin consult http://www.epa.gov/espp before each season's
use of this product."
Endangered Species. As discussed above, Agency estimates of exposure indicate risks of reproductive
effects to endangered species of birds. The acute endangered species LOC for terrestrial animals (birds
and mammals) is 0.1; for aquatic animals (freshwater or marine/estuarine fish and invertebrates) it is
0.05. The foliar and turf uses of thiram may pose an acute risk to endangered fish and invertebrate
species, and a chronic risk to endangered mammalian species. However, based on the ecological risk
assessment conducted for thiram and implementation of the mitigation procedures described below,
EPA has determined that thiram will have no effect on the Attwater Prairie Chicken. Relating to any
additional endangered species concerns, these findings are based solely on EPA's screening level
assessment and do not constitute "may affect" findings under the Endangered Species Act.
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Based on information provided by the U.S. Fish and Wildlife Service, the endangered species
profile, and communications with refuge managers, the Attwater's Prairie Chicken (Tympanuchus
cupido allwaleri) may be at risk for consuming thiram- treated seed. The seed foraging behavior of the
Attwater's Prairie Chicken, combined with the fact that seed planted in the vicinity of this endangered
species are typically incorporated at depths where the chicken is not likely to encounter the treated seed,
reduces the likelihood of exposure and risk. To further mitigate risks posed to the Attwater's Prairie
Chicken, the Agency will require label and bag tag revisions, specify minimum cotton seed planting
depths, and restrict planting of any thiram-treated seed within a one-mile zone around the perimeter of
the Attwater's Prairie Chicken preserves. EPA plans to issue new or revised County Specific Bulletins
delineating the above mitigation measures.
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I. Introduction
The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) was amended in 1988 to
accelerate the reregistration of products with active ingredients registered prior to November 1, 1984.
The amended Act calls for the development and submission of data to support the reregistration of an
active ingredient, as well as a review of all submitted data by the U.S. Environmental Protection
Agency (referred to as EPA or "the Agency"). Reregistration involves a thorough review of the
scientific database underlying a pesticide's registration. The purpose of the Agency's review is to
reassess the potential hazards arising from the currently registered uses of the pesticide; to determine the
need for additional data on health and environmental effects; and to determine whether the pesticide
meets the "no unreasonable adverse effects" criteria of FIFRA.
On August 3, 1996, the Food Quality Protection Act of 1996 (FQPA) was signed into law. This
Act amends FIFRA to require tolerance reassessment. The Agency has decided that, for those
chemicals that have tolerances and are undergoing reregistration, the tolerance reassessment will be
initiated through this reregistration process. The Act also requires that by 2006, EPA must review all
tolerances in effect on the day before the date of the enactment of the FQPA. FQPA also amends the
Federal Food, Drug, and Cosmetic Act (FFDCA) to require a safety finding in tolerance reassessment
based on factors including consideration of cumulative effects of chemicals with a common mechanism
of toxicity. This document presents the Agency's revised human health and ecological risk
assessments; and the Reregistration Eligibility Decision (RED) for thiram.
The implementation of FQPA has required the Agency to revisit some of its existing policies
relating to the determination and regulation of dietary risk, and has also raised a number of new issues
for which policies need to be created. These issues were refined and developed through collaboration
between the Agency and the Tolerance Reassessment Advisory Committee (TRAC), which was later
superceded by the Committee to Assist with Reassessment and Transition (CARAT). Both federal
advisory committees were composed of representatives from industry, environmental groups, and other
interested parties. Although FQPA significantly affects the Agency's reregistration process, it does not
amend any of the existing reregistration deadlines. Therefore, the Agency is continuing its reregistration
program while it resolves the remaining issues associated with the implementation of FQPA.
This document consists of six sections. Section I contains the regulatory framework for
reregistration/tolerance reassessment; Section II provides a profile of the use and usage of the chemical;
Section m gives an overview of the human health and environmental effects risk assessments; Section
IV presents the Agency's decision on reregistration eligibility and risk management; and Section V
summarizes the label changes necessary to implement the risk mitigation measures outlined in Section
IV. Finally, the Appendices include Data Call-In (DCI) and other information. The revised risk
assessments and related addenda are not included in this document, but are available in the public
docket, at: http://docket, epa. gov/edkpub/index.j sp. and on the Office of Pesticide Programs web page
at: http: //www, epa. gov/pesticides/reregi strati on/.
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II. Chemical Overview
A. Regulatory History
Thiram has been registered in the United States since 1948 for use as a non-systemic, protectant
dithiocarbamate fungicide. During the second phase of reregi stration, the Agency conducted a review
of the scientific data base underlying pesticide registrations and identified missing or inadequate studies.
Subsequent Data Call-Ins (DCIs) were issued in 1991 and 1995 for thiram. This Reregistration
Eligibility Decision (RED) reflects a reassessment of all data submitted to date.
In an effort to promote transparency of the reregistration process and include the public in
developing regulatory decisions, the Agency has developed a public participation process that is used
for pesticide tolerance reassessment and reregistration. This public participation process was developed
in partnership with USD A, based on EPA's and USDA's experiences with the pilot public participation
process used for the organophosphate pesticides, comments received from Tolerance Reassessment
Advisory Committee and the public during the public comment period on the proposed process and
EPA's experience with the interim process used in developing decisions for a number of non-
organophosphate pesticides during the past few years. The public participation process encompasses
full and modified versions that enable EPA to tailor the level of review to the level of refinement of the
risk assessments, as well as to the amount of use, risk, public concern and complexity associated with
each pesticide.
The Agency followed a six-phase public participation process for thiram. Consistent with the
process, EPA initiated Phase 1 of the process by transmitting the preliminary human health and
ecological risk assessments to the technical registrant for a 30-day error only correction review. In
Phase 2, EPA considered the errors that were identified by the registrant and made changes in the risk
assessments as appropriate. To initiate Phase 3 of the process on January 26, 2004, the Agency
published a Federal Register notice announcing the availability of the revised risk assessments and
supporting documents for a 60-day public review and comment period. On July 2, 2004, EPA initiated
Phase 5 of the process announcing the availability of the refined risk assessments for a 60-day public
review and comment period. EPA received approximately 75 comments, which proved to be extremely
helpful in further refining the use characterization of thiram and possible risk mitigation options.
B. Chemical Identification
Thiram:
CH
S
¦3
s
CH
¦3
Common name: Thiram
Chemical name: [tetramethyl thiuram disulfide]
Chemical Family: Dithiocarbamate
2
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Empirical formula:
CAS Registry No.:
Case number:
OPP Chemical Code:
Molecular weight:
Trade name:
Basic manufacturer:
c6h12n2s4
137-26-8
0122
079801
240.4
Thiram 65, Thiram 75, Thiram Granuflo, Defiant
Gustafson LLC, Taminco, Inc.
Technical thiram is a crystalline solid with a melting point of 142-150 C, bulk density of 0.32-
0.35 g/mL, octanol/water partition coefficient (Pow) of 39.5-54.1, and vapor pressure of 1.6-1.8 x 10~5
Torr at 25 C.
C. Use Profile
Type of Pesticide
Thiram is a member of the dithiocarbamate class of non-systemic fungicides.
Summary of Use Sites
Thiram is used as a fungicide to prevent crop damage in the field. It is used on, and currently has
tolerances (CFR §180.132) in/on apples, peaches, and strawberries. It is also used as a seed protectant
(e.g. small seeded vegetables, large seeded vegetables, cereal grains, other seeds, coniferous seeds,
cotton seed, ornamental seeds, and soybeans) and to protect turf from fungal diseases. In addition,
thiram is used as an animal repellent to protect crops from damage by rabbits, rodents, and deer.
Regarding the foliar uses, because thiram is a non-systemic, protectant fungicide which is not
subject to pest resistance development, it is typically used throughout most of the crop cycle (especially
during the bloom and pre-harvest periods). Thiram is typically alternated or tank-mixed with other
fungicides, which are systemic with single-site modes of action and prone to pest resistance problems.
Accordingly, thiram is a critical pest resistance management tool used to delay the development of pest
strains resistant to the systemic fungicides.
It was also determined that thiram plays a very important role in areas of California and Florida
where lengthy growing seasons exist. Thiram is relied upon after the seasonal maximum amounts of
other fungicides, primarily captan, has been utilized.
The seed use of thiram on a variety of crops is also important. Thiram controls a wide spectrum
of pathogens, is cost-effective, and is widely accepted for use on exported seed.
3
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Target Pests
On apples: apple blotch, apple scab, bitter rot, bitter pox, black rot on fruit/foliage,
Brook's spot, Bull's eye rot, fly speck, gray mold rot, sooty blotch, white rot, cedar
apple rust, and quince rust;
On peaches: brown rot blossom blight and fruit rot, peach leaf curl, rhizopus rot, and peach
scab;
On strawberries: gray mold;
On treated seeds (of many varieties): damping off, seed decay, seedling blights, covered
kernel smut of sorghum, and loose smut and bunt of wheat;
On turf: dollar spot, brown patch, and fusarium patch.
Thiram acts by concomitant inhibition of spore germination and mycelial growth through multi-
site interference of enzyme processes associated with respiration. As an animal repellent, it creates a
taste aversion to deter feeding.
Formulation Types Registered
Formulations include dust, wettable powder, water dispersable granule, flowable concentrate, dry
flowable, soluble concentrate, and ready-to-use liquid.
Methods of Application
Currently, thiram formulations may be applied to apples, peaches, and strawberries using
groundboom, aerial equipment, airblast sprayer, soil incorporation equipment, high and low pressure
handwand, backpack sprayer, push-type granular spreader, tractor-drawn drop-type spreader,
paintbrush, and sprinkler can. Commercial seed applicators use automated machinery that mixes and
applies thiram to seeds as they are rotated through a metal drum or cylinder; these systems are used for
both liquid and dust treatments. On-farm liquid applicators use a portable mechanical mixing system
that applies thiram to seeds as they are rotated through a metal cylinder. On-farm dust applicators pour
thiram into the seed chamber of the planter and mix the product by hand with a stick or paddle, just
prior to planting. Ornamental bulbs may be treated by dip tank application, drill box, and duster. As
discussed above, the thiram technical registrants are no longer supporting aerial and hand/spoon
applications of granular formulations, residential (homeowner) use as fungicide on bulbs, flower seeds,
greenhouse and nursery cuttings, and pruning paints, or on-farm seed treatment for peanuts.
Label Use Rates
For foliar spray applications, application rates range from 2.6 to 4.5 lbs. of active ingredient per
acre (ai/A) and the maximum number of applications per season ranges from five to 15. The animal
repellent rate is 1 lb. ai per 1 gallon spray and the bulb dip rate is 1 lb. ai per 6 gallon dip solution. Seed
treatment application rates range from 0.031 to 2 lbs. ai per 100 lbs. (ai/cwt.) of seed.
4
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D. Estimated Usage of Thiram
Based on available data, approximately 165,000 lbs. of thiram are applied to 35,000 acres of
strawberries, apples, and peaches annually and up to 631,000 lbs. ai/year are used to treat about 1.3
billion pounds of seed. The seed treatment use in terms of total pounds active ingredient is allocated as
follows: cereal grains (73%), cotton seed (12%), large seeded vegetables (7%), soybeans (4%), and
small seeded vegetables (3%). The largest foliar markets for thiram in terms of total pounds active
ingredient are strawberries (60%), apples (35%), and peaches (3%). The remaining foliar uses are on
ornamentals. Most of the foliar usage is in California, Florida, Michigan, New Jersey, New York,
Oregon, Pennsylvania, and Washington.
In 2003, Pennsylvania applied thiram to 17% of the total acres for peaches (646 acres out of 3,800
acres) based on USDA/NASS data. This is likely to be a sporadic incidence because thiram use was not
reported in Pennsylvania in other years. Pennsylvania accounts for only about 3% of the total acres for
peaches in the United States, while California, Georgia, and South Carolina together comprise more
than 80%). However, Pennsylvania is the only state that shows thiram use on peaches in 2003. Even in
2003 with a relatively higher % acres treated with thiram in Pennsylvania, thiram use on peaches are
still less than 3% of the total foliar usage of thiram.
5
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III. Summary of Thiram Risk Assessment
The purpose of this summary is to assist the reader by identifying the key features and findings of
the human health and ecological risk assessments, and to enhance understanding of the conclusions
reached in the assessments. The list of EPA's human health and ecological risk assessments, and
supporting information that were used to formulate the findings and conclusions for the fungicide
thiram can be found in the OPP public docket, located in Room 119, Crystal Mall #2, 1801 Bell Street,
Arlington, VA or viewed via the Internet at: http://docket.epa.gov/edkpub/index.jsp under the docket
number OPP-2004-0183. In addition, documents may be downloaded or viewed via the Internet at:
http ://www.epa. gov/pesticides/reregistration/.
EPA issued its refined risk assessments on thiram and made them available for public comment
on July 2, 2004. The 60-day public comment period on the refined risk assessments ended August 31,
2004. In response to the comments received and additional information, the Agency will issue its reply
to comments and will post it, along with this Thiram RED in the OPP public docket.
A. Human Health Risk Assessment
1. Dietary Risk from Food
a. Toxicity and Carcinogenicity
(For a complete discussion, see section 3.1 of the Human Health Risk Assessment.)
The toxicology data base is adequate to characterize the toxicity of thiram. Thiram exhibits low to
moderate acute toxicity via the oral (Toxicity Category HI) and dermal (Toxicity Category m) routes of
exposure. Thiram is considered to be moderately toxic via the inhalation route of exposure (Toxicity
Category II). It is a moderate eye irritant (Toxicity Category II), a slight dermal irritant (Toxicity
Category IV) and a moderate skin sensitizer.
Table 1. Acute Toxicitv Data on T
liram
Guideline No./ Study Type
MRID No.
Results
Toxicitv
Category
870.1100 Acute oral toxicity
00153548
LD50 = 1,800 mg/kg/day
III
870.1200 Acute dermal toxicity
00259250
LD50 > 2,000 mg/kg/day
III
870.1300 Acute inhalation toxicity
00165855
LC50 >0.1 mg/L
II
870.2400 Acute eye irritation
00259250
Moderate eye irritant
II
870.2500 Acute dermal irritation
00259250
-
IV
870.2600 Skin sensitization
00153068
Moderate skin sensitizer
Thiram is a neurotoxicant and can also act as a developmental toxicant. The neurotoxic effects of
thiram seen in laboratory animals are lethargy, reduced tail pinch response, no tail pinch response,
6
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reduced brain weights, and reduced motor activity. Developmental effects seen in laboratory animals
include severe fetal malformations including central nervous system defects as well as protruding
tongue and cleft palates after in utero exposure to thiram at dose levels which did not cause maternal
toxicity.
The subchronic toxicity profile for thiram indicates that hematology, clinical chemistry and body
weight are the parameters affected after subchronic exposure to the compound for all species evaluated.
The chronic toxicity profile for thiram indicates that the liver, blood and urinary system are the
target organs for this chemical. In a combined chronic/cancer study in rats, effects included changes in
hematology parameters, increased incidence of bile duct hyperplasia, and reduction in body weight gain.
At higher doses in this study, the severity of the toxicity described above was increased and changes in
clinical chemistry parameters were reported. In a chronic oral toxicity study in dogs, effects were
manifested as elevated cholesterol levels and increases in liver-to-body weight ratio. At higher dose
levels, the signs of toxicity were more severe. Signs of toxicity in a carcinogenicity study in mice
included decreases in body weight gain, anemia, as well as non-cancerous lesions in the eyes, stomach
and urinary bladder. At higher doses, the severity of these signs of toxicity was greater.
The results of two multigeneration reproduction toxicity Studies in rats did not reveal increased
susceptibility of the young after in utero and perinatal exposure to Thiram. In both studies, the effects
noted at the Lowest-Observed-Adverse-Effect-Level (LOAEL) in the offspring and parental animals
were limited to decreases in body weight and/or body weight gain.
The Agency is requiring a developmental neurotoxicity (DNT) study be conducted and submitted
for consideration by the Agency. That recommendation was based on the weight of the evidence
including: 1) findings of CNS defects in the developmental study in rats; and 2) neurotoxic effects in
the acute and subchronic neurotoxicity study.
Thiram is readily absorbed (via the oral route), distributed, extensively metabolized and
eliminated primarily in the expired air mostly within 24 hours of administrations. No significant
residues remain after 72 hours.
In carcinogenicity studies, thiram did not demonstrate any biologically significant evidence of
carcinogenic potential. Thiram is classified as "not likely to be carcinogenic to humans."
b. FQPA Safety Factor
(For a complete discussion, see section 3.2 of the Human Health Risk Assessment.)
An uncertainty factor (UF) of 1000X was initially applied to all populations to account for inter-
species extrapolation (10X), intra-species variation (10X), and a database uncertainty factor (10X). A
Database Uncertainty Factor (UFDB) is applied to all dietary and residential exposure scenarios to
account for the lack of a developmental neurotoxicity study (DNT) study. The Agency concluded that a
Developmental Neurotoxicity Study (DNT) on thiram is necessary based on a weight of evidence
including: 1) findings of central neurological system defects as seen in the Developmental Study in rats
(MRID 00259810-02); and 2) neurotoxic effects in the Acute and Subchronic Neurotoxicity Study
7
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(MRID 42912401 and 43012701, respectively). Because the thiram toxicology database does not
include a DNT study, a Database Uncertainty Factor is necessary to be protective of children. This
Uncertainty Factor is applied only to exposure scenarios that are expected for children or pregnant
women, and thus is not applied to occupational exposure scenarios.
The Agency determines the appropriate size of the Database Uncertainty Factor by comparing the
NOAEL from an acceptable reproduction study on the subject pesticide with a dose level that the
Agency assumes would be the NOAEL from a DNT study on the subject pesticide, if one were
available. A recent analysis of data from DNT studies previously submitted to the Agency suggests that
NOAELs lower than the lowest dose tested in the reproduction study are unlikely to occur.
In the case of thiram, the lowest dose tested in the rat reproduction study 1.7 mg/kgbw-day. The
Agency therefore assumes that a DNT study on thiram would yield a NOAEL of approximately 1.7
mg/kgbw-day. The Agency's determination of the size of the Database Uncertainty Factor is derived by
dividing the point of departure used for each exposure pathway by the assumed DNT NOAEL of 1.7
mg/kgbw-day. If the point of departure for a particular risk assessment is higher than the assumed
NOAEL, a Database Uncertainty Factor is required. If the difference is in the range of 3X, a 3X factor
is used. If it is larger than 3X, a 10X factor is used. If the point of departure is equal to or lower than
the assumed NOAEL, a Database Uncertainty Factor is not required since it is concluded that the DNT
is unlikely to yield a point of departure more sensitive than that currently being used for that assessment.
Therefore, based on this approach, acute dietary risk estimates will be reduced by approximately
3-fold, with a resulting Database Uncertainty Factor of 3X. Chronic dietary risk estimates will be
reduced by 10-fold and the target MOEs for all occupational and residential risk assessments will now
be 100.
The HLARC concluded that the Special FQPA Factor could be reduced to IX. This conclusion is
based on the outcome of the degree of concern analysis that failed to identify any residual uncertainties.
The Special FQPA Safety Factor recommended by the HIARC assumes that the exposure databases
(dietary food, drinking water, and residential) are complete and that the risk assessment for each
potential exposure scenario includes all metabolites and/or degradates of concern and does not
underestimate the potential risk for infants and children.
c. Population Adjusted Dose (PAD) & Reference Dose (RfD)
(For a complete discussion, see section 4.2 of the Human Health Risk Assessment.)
The acute dietary endpoint was derived from an acute neurotoxicity study in rats.
The NOAEL for neurotoxic effects is 5 mg/kg and the LOAEL is 150 mg/kg based on the following
effects seen in laboratory animals: lethargy, lower temperature, reduced startle response, no tail pinch
response, reduced motor activity, and reduced brain weights.
The FQPA safety factor is IX, however, a 3X database uncertainty factor was used to account for
the lack of a required DNT study. The results of this study could affect the endpoints used for risk
assessment. Table 2 below summarizes the toxicological dose and endpoints used in the thiram dietary
risk assessment.
8
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Table 2. Summary of Toxicolosical 11
»ose and EndDoints for Thiram
i:\posuiv
Seen si rio
Dose I sed in Kisk
Assessment. 1 I"1
Special l-'QI'A Sal'el\
I'iielur iind 1 .eu'l of
C oncern lor Kisk
Assessment
Siud\ and To\icolo»ical IHTeels
Acute Dietary
(All Populations)
NOAEL3 = 5
mg/kg/day
UF = 300*
Acute RID = 0.0167
mg/kg/day
FQPA SF2 = 1
aPAD = acute RfD
FQPA SF
= 0.0167 mg/kg/day
Acute Neurotoxicity Study - Rat
LOAEL4 = 150 mg/kg/day based on FOB9
effects (lethargy, lower temperature,
reduced startle response, no tail pinch
response), reduced motor activity, and
reduced brain weights
Chronic Dietary
(All populations)
NOAEL= 1.5
mg/kg/day
UF = 100
Chronic RfD =
0.015 mg/kg/day
FQPA SF = 1
cPAD5 =
chronic RfD
FQPA SF
= 0.015 mg/kg/day
Combined Chronic
Toxicity/Carcinogenicity Study - RAT &
Chronic Oral Toxicity Study - DOG
LOAEL =7.3 mg/kg/day based on
changes in hematology, clinical chemistry
incidences of bile duct hyperplasia, and
reduction in mean body weight gain seen
at 7.9 mg/kg/day in conjunction with
elevated cholesterol levels and increased
liver weights reported in the Chronic Oral
Toxicity Study in Dogs at 2.6 mg/kg/day
Short-Term
Incidental Oral (1-
30 days)
and
Intermediate-T erm
Incidental Oral
(1-6 months)
NOAEL= 1.5
mg/kg/day
Residential LOC8 for
MOE7= 100
Occupational = NA10
Multigeneration Reproduction Toxicity
Study and Combined Chronic
Toxicity/Carcinogenicity Study - RAT &
Chronic Oral Toxicity Study - DOG
LOAEL =4.7 mg/kg/day based on
decreased pup weight/pup weight gain.
Short-Term Dermal
(1 to 30 days)
and
Intermediate-Term
Dermal
(1 to 6 months)
NOAEL=
300 mg/kg/day
Residential LOC for
MOE = 100
Occupational LOC for
MOE = 100
21-Day Dermal Toxicity/Rabbit
LOAEL = 1000 mg/kg/day based on
decreases in body weight and food
consumption as well as alterations in
clinical chemistry.
9
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i:\posuiv
Seen si rio
Dose I sod in Kisk
Assessment. 1 I"1
Special l-'QI'A SiilVlj
I'ilClor <111(1 I.CU'I of
C oncern lor Kisk
Asscssmcnl
Siud\ and To\icolo»ical EITccIs
Long-Term Dermal
(>6 months)
NOAEL=
1.5 mg/kg/day
(dermal absorption
rate = 1% when
appropriate)
Residential LOC for
MOE = 100
Occupational LOC for
MOE =100
Combined Chronic
Toxicity/Carcinogenicity Study - RAT &
Chronic Oral Toxicity Study - DOG
LOAEL =7.3 mg/kg/day based on
changes in hematology, clinical chemistry
incidences of bile duct hyperplasia, and
reduction in mean body weight gain seen
at 7.9 mg/kg/day in conjunction with
elevated cholesterol levels and increased
liver weights reported in the Chronic Oral
Toxicity Study in Dogs at 2.6 mg/kg/day
Inhalation
(All durations)
NOAEL= 1.5
mg/kg/day
(inhalation
absorption rate =
100%)
Residential LOC for
MOE = 100
Occupational LOC for
MOE = 100
Combined Chronic
Toxicity/Carcinogenicity Study - RAT &
Chronic Oral Toxicity Study - DOG
LOAEL =7.3 mg/kg/day based on
changes in hematology, clinical chemistry
incidences of bile duct hyperplasia, and
reduction in mean body weight gain seen
at 7.9 mg/kg/day in conjunction with
elevated cholesterol levels and increased
liver weights reported in the Chronic Oral
Toxicity Study in Dogs at 2.6 mg/kg/day.
Cancer (oral,
dermal, inhalation)
NOT LIKELY TO BE CARCINOGENIC TO HUMANS
*A database uncertainty factor of 3X was applied in addition to the usual inter- and intraspecies safety factor.
1. UF = uncertainty factor. 2. FQPA SF = Special FQPA safety factor. 3. NOAEL = no observed adverse effect level. 4.
LOAEL = lowest observed adverse effect level. 5. PAD = population adjusted dose (a = acute, c = chronic). 6. RfD =
reference dose. 7. MOE = margin of exposure. 8. LOC = level of concern. 9. FOB = functional observational battery. 10.
NA = Not Applicable
d. Exposure Assumptions
(For a complete discussion, see section 4.2 of the Human Health Risk Assessment.)
The acute dietary probabilistic assessment was conducted using the Dietary Exposure Evaluation
Model (DEEM-FCID™). There are no Food and Drug Administration or U.S. Department of
Agriculture Pesticide Data Program (PDP) monitoring data available for thiram because the currently
available analytical methodology detects carbon disulfide, a common metabolite for thiram and other
dithiocarbamates, and therefore cannot quantify thiram residues with precision. Because field trial data
were used, the assessment is considered conservative and could be further refined if sufficient
monitoring data were available. However, percent crop treated information, and washing, cooking, and
other processing factors were incorporated into the dietary assessment to provide an additional level of
refinement.
10
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For the chronic dietary (food) risk assessments, exposure was calculated using field trial residue
and percent crop treated data. Estimates of average residues for foods (e.g., orange) or food-forms (e.g.,
orange-juice) of interest are multiplied by the averaged consumption estimate of each food/food-form of
each population subgroup. Exposure estimates are expressed in mg/kg body weight/day and as a
percent of the cPAD.
e. Acute Dietary (Food) Risk
(For a complete discussion, see section 4.2 of the Human Health Risk Assessment.)
Acute dietary risk is calculated considering what is eaten in one day. Acute dietary exposure
that is less than 100% of the acute Population Adjusted Dose (aPAD) does not exceed the Agency's
level of concern. The aPAD is the acute Reference Dose (RfD) adjusted by the FQPA Safety Factor
(FQPA SF). The acute RfD is the dose at which an individual could be exposed in a single day with no
adverse health effects, which is equal to the NOAEL divided by the uncertainty factor. For thiram,
because the FQPA SF is 1, the acute RfD and the aPAD are numerically the same (0.0167 mg/kg/day).
The acute risk estimates are of concern at the 99.9th exposure percentile for the general U.S.
population (114% of the aPAD) and all the population subgroups outlined in Table 3. The acute dietary
exposure estimate for children 1-2 years old, the highest exposed population subgroup, is 302% of the
aPAD.
These risks will be mitigated to acceptable levels (peaches alone at 9% of the aPAD) through
voluntary cancellation of apples and removal of strawberries from labels, pending receipt and review of
additional data (developmental neurotoxicity and strawberry "processing" studies) and reevaluation of
risk.
Table 3. Results of Acute Dietary Exposure Analysis
Populiiliun Subgroup
iil'AI)
(ni»/k»/tlsn)
«W)lh IVrci-nlik-
i:\posuiv (m<>/k<>/(lii\)
"« iil'AI)
General U.S. Population
0.0167
0.019022
114
All Infants (< 1 year old)
0.0167
0.021088
127
Children 1 -2 years old
0.0167
0.050268
302
Children 3-5 years old
0.0167
0.043316
260
Children 6-12 years old
0.0167
0.030360
182
Youth 13-19 years old
0.0167
0.013902
83
Adults 20-49 years old
0.0167
0.012330
74
Females 13-49 years old
0.0167
0.014078
84
Adults 50+ years old
0.0167
0.011278
68
11
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f. Chronic Dietary (Food) Risk
(For a complete discussion, see section 4.2 of the Human Health Risk Assessment.)
Chronic dietary risk is calculated by using the average consumption values for food and average
residue values on those foods over a 70-year lifetime. The chronic dietary assessment was based on the
Dietary Exposure Evaluation Model (DEEM™) using percent crop treated and anticipated residues
based on field trial data. Chronic dietary exposure is then compared to the chronic Population Adjusted
Dose (cPAD). A risk estimate that is less than 100% of the cPAD does not exceed the Agency's level
of concern. The cPAD is the chronic Reference Dose (RfD) adjusted by the FQPA safety factor. The
RfD is the dose at which an individual could be exposed over a lifetime with no adverse health effects.
Estimated chronic dietary exposure and risk are below the Agency's level of concern, with 2.8%
or less of the cPAD consumed for all population subgroups. Exposure for the U.S. general population
is less than 1% of the cPAD (Table 4).
Table 4. Chronic Dietary (Food) Exposure Estimate and Percent of Chronic RfD - Tier 1
Exposure Analysis (Assumes Tolerance Level Residues and % Crop Treated with Anticipated
Residue Levels based on Field Studies)
Population Subgroup
cl'AI)
(m<>/k<>//k<>/(lii\)
"i. olWI)
General U.S. Population
0.015
0.000121
<1
All Infants (< 1 year old)
0.015
0.000102
<1
Children 1 -2 years old
0.015
0.000422
2.8
Children 3-5 years old
0.015
0.000336
2.2
Children 6-12 years old
0.015
0.000205
1.4
Youth 13-19 years old
0.015
0.000087
<1
Adults 20-49 years old
0.015
0.000079
<1
Females 13-49 years old
0.015
0.000095
<1
Adults 50+ years old
0.015
0.000099
<1
g. Cancer Dietary Risk Assessment
In carcinogenicity studies in male and female rats and in male and female mice, thiram did not
demonstrate any biologically significant evidence of carcinogenic potential. Thiram is classified as "not
likely to be carcinogenic to humans." Therefore, no cancer risk assessment was conducted.
2. Dietary Risk from Drinking Water
(For a complete discussion, see section 4.3 of the Human Health Risk Assessment.)
12
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Drinking water exposure to pesticides can occur through groundwater and surface water
contamination. EPA considers both acute (one day) and chronic (lifetime) drinking water risks and uses
either modeling or actual monitoring data, if available, to estimate those risks. To determine the
maximum allowable contribution from water in the diet, EPA first looks at how much of the overall
allowable risk is contributed by food and then calculates a drinking water level of comparison
(DWLOC). The DWLOC represents the maximum contribution to the human diet (in ppb or ug/L) that
may be attributed from residues of a pesticide in drinking water after dietary exposure is subtracted from
the acute or chronic PAD. Risks from drinking water are assessed by comparing the DWLOC, to
determine whether modeled or monitored estimated environmental concentrations (EECs) in both
surface and groundwater exceed this level. EECs that are less than the DWLOC are not of concern.
For thiram, because estimates of food-only exposure exceed 100% of the aPAD, the acute DWLOCs
are zero; that is, any drinking water exposure would constitute a risk concern. However, a DWLOC
calculation was performed assuming no exposure from food to evaluate potential acute risk posed by
drinking water alone. Based on this evaluation, drinking water alone does not exceed the Agency's
level of concern.
Table 5. Drinking Water Acute Dietary Exposure
Population
(•roups
iil'AI)
M;i\imum Allow sihlc
Drinking \\ ;iUt
l.\posUIV
(m<>/k<>/)
snutow
(onci'iilnilion
(ppl>)
U.S. General
Population
0.0167
0.005
1750
180
0.84
Females 13- 49
0.0167
0.005
1500
180
0.84
Infants and
Children
0.0167
0.005
500
180
0.84
a. Surface Water
Tier II surface water EECs were generated for non-residential turf, apples, and cotton seed uses
using the PRZM/EXAMS model with the Index Reservoir and Percent Crop Area (PCA factor). The
Index Reservoir provides a more refined assessment that uses a standard watershed combined with
local soils, weather, and cropping practices to represent a vulnerable watershed that could support a
drinking water supply for each crop. Comparisons between DWLOCs and the highest EEC of 4.3 ppb
in surface water indicate that the level of concern for thiram residues in drinking water is not of concern
when assessing chronic dietary risk.
b. Ground Water
Groundwater EECs for thiram were estimated using the SCI-GROW model under conditions of
maximum exposure. SCI-GROW provides a screening level groundwater concentration and assumes
the pesticide is used at the maximum allowed label rate in areas with groundwater that is exceptionally
vulnerable to contamination. These vulnerable areas are characterized by high rainfall, rapidly
permeable soil, and shallow aquifer. Comparisons between DWLOCs and the highest EECs of 0.84
13
-------
ppb in groundwater indicate that the level of concern for thiram residues in drinking water has not been
exceeded when assessing chronic dietary risk.
The modeled chronic drinking water EECs from surface and groundwater sources used for this
risk assessment are presented in Table 6.
Table 6. Chronic Drinking Water EECs & DWLOCs (Thiram)
Population
(iioups
Dietary
I ¦!\posure from
Analysis
(mg/kg/day)
cPAD
(mg/kg/day)
Maximum
Allowable
Drinking Water
I Aposnre
(mg/kg/day)
DWI.OC,!,,.
(ppb)
PR/.M/PXAMS
365 day NX's
(ppb)
SCI GROW
Concentration
(ppb)
U.S. General
Population
0.000121
0.015
0.015
48.30
4.3
0.84
Females
(13-49 years)
0.000095
0.015
0.015
42.15
4.3
0.84
Children
(1-2 years)
0.000422
0.015
0.015
10.80
4.3
0.84
3. Residential Risk
Thiram is not available for sale or use by homeowner applicators. As such, all residential risks
were calculated related to the non-residential turf uses that include golfing for adults and toddler
exposures in areas that can be treated with thiram by certified pesticide applicators. MOEs for golfers
are not of concern to the Agency (MOE=764 at Day 0), and therefore no risk mitigation measures are
required to address this scenario.
To protect children from scenarios of concern (MOE= 4) for exposure to thiram treated turf)
and to further protect from exposure to ornamentals treated with thiram as a deer repellent, the Agency
is requiring the following label modifications:
Deer Repellent Use:
Use one quart of this product in 3 to 7 gallons of water for application to 1000ft2
Applications to ornamentals will be restricted to the following 17 Northern states and
applications will occur during the winter season only (October thru March):
OH, PA, NY, MI, CT, MA, IN, IL, NJ, WV, MN, WI, VT, NH, RI, DE, and
MD.
Cancellations of Turf/Other Uses:
Turf applications to parks, athletic fields and commercial landscapes.
All turf applications for turf grown for sale or other commercial use such as sod.
All homeowner and retail uses on residential lawns and turf
Residential homeowner use as a fungicide on bulbs, flower seeds, greenhouse and
nursery cuttings, and pruning paints.
14
-------
Through these label amendments and voluntary cancellations to remove all homeowner uses
from Taminco, the Agency believes exposure to the deer repellent use will be insignificant and therefore
not of concern. No additional mitigation is necessary.
a. Aggregate Risk
(For a complete discussion, see section 5.0 of the Human Health Risk Assessment.)
Acute risks from aggregate exposures are not of concern. Models have been used to estimate
ground and surface water concentrations. The DWLOCs calculated to assess the surface water
contribution to acute (noncancer) dietary exposure range from 1750wg/L (for the U.S. general
population) to less than 500wg/L (infants and children). The surface water EEC (47.8ppb) is
significantly less than the acute DWLOC. The groundwater EEC (0.84) is also significantly less than
the acute DWLOC. These DWLOCs were calculated assuming no exposure from food in order to
evaluate potential acute risk posed by drinking water alone. However, if dietary exposure due to peach
consumption had been included in the DWLOC calculations, the LOCs would have been only
approximately 10% lower, i.e., the lowest DWLOC would have been 450wg/L. Thus, the Agency
concludes with reasonable certainty that aggregate exposure to food and drinking water will not result in
an unacceptable acute risk.
Short-term aggregate risks are not of concern. DWLOCs were calculated based upon average
food residues and the residential post-application exposure scenario(adult golfers). Because the inputs
to calculate short-term aggregate risks are very low (cPAD=2.8% and the MOE at day 0 for golfers is
794), the Agency concludes with reasonable certainty that aggregate exposure to food, drinking water
and residential exposures will not result in an unacceptable risk.
Chronic risks from aggregate exposures are not of concern. The DWLOC calculated to assess
the surface water contribution to chronic (noncancer) dietary exposure is a range from 48.30wg/L (for
the U.S. general population) to less than 10.80wg/L (infants and children). The surface water EEC (4.3
ppb) is less than the chronic DWLOC, indicating that chronic exposure to thiram in food and drinking
water from surface water sources is below the Agency's level of concern. The groundwater EEC (0.84
ppb) is also less than the chronic DWLOC, indicating that chronic exposure to thiram in food and
drinking water from groundwater sources is below the Agency's level of concern. Since the model-
based estimates for concentrations in surface water and groundwater are below the calculated chronic
DWLOC, the Agency concludes with reasonable certainty that aggregate exposure to food and drinking
water will not result in an unacceptable chronic risk.
4. Occupational Risk
(For a complete discussion, see section 7.0 of the Human Health Risk Assessment.)
There is potential exposure to workers who treat seed with thiram in both commercial and on-
farm settings. The Agency calculated the potential exposure and risk to workers from commercial and
on-farm seed treatment and from loading and planting treated seed. Risks were calculated using the
MOE approach. The level of concern MOE was 100 for all assessments. This is based on the
15
-------
conventional uncertainty factor of 100X (10X for intraspecies extrapolation and 10X for interspecies
variation).
For thiram uses, the Agency identified 28 major occupational exposure scenarios based on the
types of equipment and techniques that potentially can be used for thiram applications. Most of the
scenarios were classified as having short-term and intermediate-term exposures (up to 30 days and 30
days to several months, respectively), though the hazard components are identical for short- and
intermediate-term exposures. The calculated results reflect the risks associated with all expected
durations of exposure. Refer to the Thiram - Revised HED Chapter of the Reregistration Eligibility
Document (RED), December 16, 2003, for the complete list of scenarios.
a. Toxicity
A NOAEL from the 21-day dermal toxicity study in rabbits using technical grade thiram was
used to calculate results for short- and intermediate-term durations (i.e., 300 mg/kg/day). A NOAEL
based on a chronic study in rats, and a chronic study in dogs (i.e., 1.5 mg/kg/day), was used to calculate
inhalation risks and long-term dermal risks.
b. Occupational Risk Assessment
Short-term and intermediate-term risks were calculated for different exposure scenarios at
different levels of protection.
For occupational handlers, MOEs are greater than or equal to 100 at some level of protection for
most scenarios. Current thiram labels typically require that handlers wear long pants, long-sleeved
shirts, and gloves. Respirators are generally not required.
The scenarios with the highest associated risk also have high daily chemical use amounts based
on application rates, high acreages/amounts treated, and/or the exposures for the scenarios in question
are relatively high. Generally, the scenarios with highest risk include some loading scenarios for aerial
applications, aerial granular application, some handheld equipment use, and a few commercial and on-
farm seed treatment scenarios. Current label requirements appear to be inadequate to keep exposures
below the level of concern for most scenarios except for operations where exposures and/or the amount
of chemical used is low. Scenarios where MOEs do not exceed 100 at any level of protection, including
the use of engineering controls, include some loading scenarios for aerial applications (MOEs 41 to 62),
some handheld equipment use (MOEs 8 to 44), and a few commercial and on-farm seed treatment
scenarios (MOEs 24 to 80).
The Agency revised the MOEs for certain scenarios. These revisions are reflected in the table
below. The ORE assessment for the repellency scenarios was based on the standard assumptions of 40
and 1,000 gallon volumes handled per day for surface and foliar dilute spray applications as outlined in
ExpoSAC SOP #9, "Daily Acreage Treated in Agriculture." The Agency revised the MOEs for the
repellency scenarios based on data which clarified the sizes of the treated areas. In addition, the ORE
assessment for onion seed treatment was revised with by lowering the assumed throughput rate of up to
800,000 lbs. seed treated per day to 88,000 lbs. per day. The revised throughput rate is based on the
ExpoSAC SOP #15, "Volume of Seed Treated and Planted per Day." Given that the throughput rate is
16
-------
nine times lower than originally assumed, the resulting MOEs for the commercial onion seed treatment
scenarios are nine times greater and range from 220 to 730 instead of 24 to 81 as originally calculated.
Revised minimum required PPE is outlined in Section IV.
Table 7. Summary of Short-/Intermediate-Term C
~ccuDational Handler Risks
Mixer/Loaders
la Dry Flowable: Aerial
2.6 (peaches)
3.3-4.5 (apples/strawberries)
16.3-24.5* (turf-sod farm)
350
350
80
105
138-188
111-166
Baseline1
SL2/GL/PF55
SL/GL/PF5
lb Dry Flowable:
Airblast
2.6-4.5 (apples/peaches)
40
530-917
Baseline
lc Dry Flowable:
Groundboom
(incl. In-furrow)
3.3 (strawberries)
16.3-24.5 (sod farm turf)
16.3 (golf course turf)
24.5 (golf course turf)
0.0025-0.35 (SSV/LSV/cereals/others)
80
80
40
40
80
362
111-166
221
146
3409-477273
Baseline
SL/GL/PF5
SL/GL/PF5
Baseline
Baseline
Id Dry Flowable:
High Press HW Sprayer
1.3 lb ai/gal (repellency)
1000 gal.
(1000 ft2)
167
(2004)
SL/GL/PF5
le Dry Flowable:
Right of Way Sprayer
1.3 lb ai/gal (repellency)
1000 gal.
(1000 ft2)
167
(2004)
SL/GL/PF5
If Dry Flowable:
Paint-on
1.3 lb ai/gal (repellency)
1 gal.
73427
Baseline
2 Granular:
Aerial & Ground Applications
16.3-24.5 (sod farm)
16.3-24.5 (golf course)
80
40
143-215
286-430
SL/GL/PF5
SL/GL/PF5
3a Wettable Powder:
Aerial
2.6-4.5 (apples/peaches/strawberries)
16.3-24.5 (sod farms/golf courses)
350
80
231-399
185-279
EC3
EC
3b Wettable Powder:
Airblast
2.6 (peaches)
4.5 (apples)
40
40
107
113
SL/GL/PF5
SL/GL/PF106
3c Wettable Powder:
Groundboom
(Incl. In-furrow)
3.3 (strawberry)
16.3-24.5 (sod farm & golf course turf)
0.0025-0.21 (SSV/LSV/cereals/others)
0.35 (others-peanuts)
80
40-80
80
80
1376
185-557
102-8537
397
EC
EC
Baseline
SL/GL/PF5
3d Wettable Powder:
High pressure handwand sprayer
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
280
(3360)
EC
3e Wettable Powder:
Right-of-way sprayer
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
280
(3360)
EC
3f Wettable Powder:
Paint-On
1.3 lb ai/gal. (repellency)
1 gal.
1313
Baseline
4a Liquids:
Aerial
2.6-4.5 (apples/peaches/strawberries)
16.3-24.5 (sod farm turf)
350
80
188-325
151-227
SL/GL/PF5
SL/GL/PF5
4b Liquids:
Airblast
2.6-4.5 (apples/peaches)
40
444-768
SL/GL/NR4
4c Liquids:
Groundboom
(incl. In-furrow)
3.3 (strawberries)
16.3-24.5 (sod farm turf)
16.3 (golf course turf)
24.5 (golf course turf)
0.0025-0.35 (SSV/LSV/cereals/others)
80
80
40
40
80
303
151-227
123
302
239-33440
SL/GL/NR
SL/GL/PF5
SL/GL/NR
SL/GL/PF5
Baseline
17
-------
4d Liquids:
High pressure handwand sprayer
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
228
(2736)
SL/GL/PF5
4e Liquids:
Right-of-way sprayer
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
228
(2736)
SL/GL/PF5
4f Liquids: Paint-On
1.3 lb ai/gal. (repellency)
1 gal.
5145
Baseline
4g Liquids: Bulb dip
No Data
No Data
No Data
No Data
Applicators
5a Aerial: liquid sprays
2.6-4.5 (apples/peaches/strawberries)
16.3-24.5 (turf- sod farm)
350
80
698-1208
561-843
EC
EC
5b Aerial: granular applications
16.3-24.5 (turf- sod farm)
80
41-62
MOE<100
6 Airblast: Agricultural uses
2.6 (peaches)
4.5 (apples)
40
40
160
102
Baseline
SL/GL/NR
7 Groundboom
3.3 (strawberries)
16.3-24.5 (sod farm turf)
16.3-24.5 (golf course turf)
0.0025-0.35 (SSV/LSV/cereals/others)
80
80
40
80
491
248-369
132-199
4930-648148
Baseline
SL/GL/PF5
Baseline
Baseline
8 Solid broadcast spreader (granular)
16.3-24.5 (sod farm turf)
16.3 (golf course turf)
24.5 (golf course turf)
80
40
40
194-292
129
388
SL/GL/PF5
Baseline
SL/GL/PF5
9 Right of way sprayer
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
44
(528)
MOE<100
10 High pressure handwand
1.3 lb ai/gal. (repellency)
1000 gal.
(1000 ft2)
8
(96)
MOE<100
11 Paint-on
1.3 lb ai/gal. (repellency)
1 gal.
202
SL/GL/NR
12 Dip tank
No Data
No Data
No Data
No Data
13 Granulars & baits
applied by hand
16.3 (golf course turf)
24.5 (golf course turf)
1
1
26
17
MOE<100
MOE<100
14 Granulars & baits
applied by spoon
16.3 (golf course turf)
24.5 (golf course turf)
1
1
117
227
SL/GL/NR
SL/GL/PF5
Mixer/Loader/Applicators
15 Low pressure, high volume turf gu:
(ORETF Data)
16.3 (golf course turf)
24.5 (golf course turf)
5
5
131
188
SL/GL/NR
SL/GL/PF5
16a Wettable powder,
low pressure handwand
1.3 lb ai/gallon (repellency)
40
14.3
MOE<100
16b Liquids,
low pressure handwand
1.3 lb ai/gallon (repellency)
40
248
SL/GL/PF5
17 Backpack sprayer
1.3 lb ai/gallon (repellency)
40
109
SL/GL/PF5
18 Granular, push-type spreader
16.3 (golf course turf)
24.5 (golf course turf)
5
5
139
330
Baseline
SL/GL/PF5
19 Power backpack
No Data
No Data
No Data
No Data
20 Sprinkler can
1.3 lb ai/gallon (repellency)
10
204
SL/GL/NR
Flaggers
18
-------
21 Flagger: liquid sprays
2.6-4.5 (apples/peaches/strawberries)
16.3-24.5 (turf- sod farm)
350
80
165-285
132-199
Baseline
Baseline
22 Flagger: granular applications
16.3-24.5 (turf- sod farm)
80
327-491
Baseline
Seed Treatment (lbs seed/day)
23 Mixing/loading for commercial see<
treatment
0.031-0.25 lb ai/cwt (various)
1.5 lb ai/cwt (onions)
1.5 lb ai/cwt (onions)
0.094-0.25 lb ai/cwt (corn
/cereals/LSV/SSV/cotton/peanuts)
0.10-0.25 lb ai/cwt
(cotton/cereals/soybean/SSV/LSV)
330000-800000(88000)
(Agency estimate)
330000(88000) (Agency
estimate)
800000 (88000)(Agency
estimate)
88000-718080
(Thiram Task Force)
16250-81192
(Survey Data)
105-167164
111
69
(621)
291-1247
993-5144
SL/GL/NR
SL/GL/PF5
MOE<100
SL/GL/NR
SL/GL/NR
24 Bagging commercially treated seed
0.031-1.5 lb ai/cwt (various)
1.5 lb ai/cwt (onions)
0.094-0.25 lb ai/cwt (corn
/cereals/LSV/SSV/cotton/peanuts)
0.10-0.25 lb ai/cwt
(cotton/cereals/soybeans/SSV/LSV)
330000-800000(88000)
(Agency estimate)
800000 (88000)(Agency
estimate)
88000-718080
(Thiram Task Force)
16250-81192
(Survey Data)
103-408759
43
(387)
711-2419
2429-12577
Baseline
MOE<100
Baseline
Baseline
25 Sewing bags of commercially
treated seed
0.031-0.25 lb ai/cwt (various)
1.5 lb ai/cwt (onions)
0.094-0.25 lb ai/cwt (corn
/cereals/LSV/SSV/cotton/peanuts)
0.10-0.25 lb ai/cwt
(cotton/cereals/soybeans/SSV/LSV)
330000-800000(88000)
(Agency estimate)
330000-800000(88000)
(Agency estimate)
88000-718080
(Thiram Task Force)
16250-81192
(Survey data)
201-321839
34-81
(306-729)
560-2401
1913-9903
Baseline
MOE<100
Baseline
Baseline
26 Commercially treated seed:
combined tasks
0.031-0.25 lb ai/cwt (various)
0.12-0.25 lb ai/cwt (various)
1.5-2.0 lb ai/cwt (onions & conifers)
0.094-0.25 lb ai/cwt (corn
/LSV/SSV/cotton/peanuts)
0.10 lb ai/cwt (cereals)
0.10-0.25 lb ai/cwt
(cotton/cereals/soybeans/SSV/LSV)
330000-800000(88000)
(Agency estimate)
330000-800000(88000)
(Agency estimate)
1769-800000(88000)
(Agency estimate)
88000-193600
(Thiram Task Force)
718080 (Thiram Task
Force)
16250-81192
(Survey data)
126-567
177-240
24-80
(216-720)
120-346
276
276-1428
SL/GL/NR
SL/GL/PF5
MOE<100
SL/GL/NR
SL/GL/PF5
SL/GL/NR
27 Loading/planting treated seed
0.0025-1.22 lb ai/A
(SSV/LSV/cereals/others/conifers/ornam.)
80 acres
638-112903
SL/GL/NR
28 On-farm seed treatment
0.0025-0.168 lb ai/A
(SSV/LSV/cereals/others/ornam.)
0.211b ai/A (cereals-rice)
0.35-1.22 lb ai/A (peanuts & conifers)
80 acres
80 acres
80 acres
122-8179
103
50-63
Baseline
SL/GL/NR
MOE<100
1. Baseline = Long pants, long-sleeved shirts, no gloves
2. SL = Single layer clothing with or without gloves (GL or NG)
3. EC = Engineering controls
4. NR = No respirator
5. PF5 = Protection factor 5 respirator
6. PF10 = Protection factor 10 respirator
Current label = SL/GL/NR
*The 24.5 lb ai/acre rate is associated with the Prochimie registration and must be used
in the risk assessment in the event that the Prochimie registration suspension is lifted.
Min.Req.PPE=levelof PPE where MOEs > 100, where current label is exceeded or no adequate PPEis found, results are bold. MOEswhichneverexceedlOOare
for highest feasible type of mitigation (e.g., engineering control in most cases).
19
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c. Incident Reports
There were 17 cases reported from the Incident Data System since 1992. Although all of the
reported cases occurred since 1995, approximately half of these cases (8 of 17) were reported in 1998.
Three of the cases reported affected adults following the occupational handling or clean-up of thiram
products. Thirteen of the cases reported affected the general public (3 children and 10 adults) following
the non-occupational handling of thiram products. One serious incident (a seizure episode) occurred
following the use of thiram after alcohol had been consumed the evening prior to exposure. It was
unclear if this was an occupational or non-occupational incident.
Recorded dermal effects for the reported cases were skin rashes, skin reddening, itching and
tingling of the hands, thickened skin on the palms and blisters under the skin, small bumps on the hands
and other parts of the body, and burning and redness on the face. One case recorded a dry cough
following an inhalation exposure while a splash incident to the face resulted in burning of the eyes.
During the period 1982-1996, 15 cases involving the sole use of thiram were reported. Thiram
ranked 122nd as a cause of systemic poisoning in California. A total of four persons had systemic
illnesses from thiram exposure, four experienced eye illnesses, six experienced skin illnesses, and one
person experienced a combination of these illnesses. Of the 15 cases, two persons were disabled for
one day. The 15 persons were exposed to thiram in the following manner: eight of the persons affected
were applicators; one was cleaning or repairing pesticide contaminated equipment; one experienced
exposure coincidentally; two were exposed during the shipping, warehousing or retailing of thiram; two
were packing, processing or retailing thiram; and one worker was exposed to thiram residue which was
neither agricultural or structural. According to these statistics, applicators' exposures accounted for the
majority of the recorded illnesses. The illnesses included symptoms of rashes, dermatitis, and itchy,
watery or burning eyes.
On the list of the top 200 chemicals for which National Pesticide Information Center received
calls from 1984-1991 inclusively, thiram ranked number 101 and was reported to be involved in 33
human incidents and six animal incidents, mostly pets.
B. Environmental Risk Assessment
1. Environmental Fate and Transport
The environmental fate database for thiram is incomplete. However, based in part on
supplemental fate data, thiram that is applied foliarly is expected to be sufficiently mobile and persistent
in some cases to reach surface waters in concentrations high enough to impact aquatic life. Thiram
appears to have low mobility in the environment and degrades rapidly (mean half life (VA) = 3.5 days in
a hydrolysis study). Thiram may thus be most potentially persistent in acidic waters with high turbidity
or color, such as in peat bogs, or acidified, eutrophic lakes. Under both aerobic and anaerobic
conditions in soil, data indicate that microbial metabolism of thiram is substantially biphasic, with rapid
initial degradation for about the first week, followed by a period of much slower degradation. Aerobic
aquatic data indicate rapid degradation in water. However, this may be offset by use patterns involving
multiple, repeated applications which cause repeated loadings to water bodies over the course of an
application season.
20
-------
In terrestrial field studies conducted in California, thiram (Spotrete™ 75 WDG), broadcast
applied eight times as a spray, at a nominal application rate of 10.3 lbs a.i./A/application, dissipated
with half-lives of 27.4 days and 14.4 days for bareground and turf plots of sandy loam soil (pH 8.2 to
9.6), respectively. Dissipation was again biphasic in both plots. In terrestrial field studies conducted in
North Carolina, thiram (Spotrete® 75WDG), broadcast applied eight times as a spray at a nominal
application rate of 10.3 lb a.i./A/application, dissipated with half-lives of 36 days and 62.5 days
following the last of eight applications onto a bareground plot of sand soil (pH 4.1 to 4.7) and a turf plot
of loamy sand soil (pH 4.4 to 4.5), respectively.
Volatilization is not expected to be a major route of dissipation due to thiram's low vapor
pressure (2.3 mPa at 25°C, or 1.77 x 10~7 Torr). The major thiram degradates are volatile, and so are not
expected to persist in soil or water.
2. Ecological Effects (Toxicity) Assessment
Toxicity testing reported in this section does not represent all species of bird, mammal, or
aquatic organism. Only a few surrogate species for both freshwater fish and birds are used to represent
all freshwater fish (2000+) and bird (680+) species in the United States. For mammals, acute studies
are usually limited to Norway rat or mice. Estuarine/marine testing is usually limited to a crustacean, a
mollusk, and a fish. Also, neither reptiles nor amphibians are tested. The assessment of risk or hazard
makes the assumption that avian and reptilian toxicities are similar. The same assumption is used for
fish and amphibians.
Thiram is categorized as slightly toxic to practically nontoxic to avian species on an acute oral
basis. Because the LC50 falls in the range of 1,000 to 5,000 ppm, thiram is categorized as slightly toxic
to practically nontoxic to avian species on a subacute dietary basis.
Study results indicate that thiram is practically nontoxic to small mammals on an acute oral
basis (Acute oral LC50 2,600 mg/kg). For chronic toxicity effects a reduction in body weight of
mammals was observed at a NOAEC of 1.9 mg/kg/day. Thiram is practically nontoxic to the honeybee
(LD50>11 |ig/bee).
21
-------
Table 8. Summary of Acute and Chronic Toxicity Data from Core Studies for Terrestrial
Organisms ExDOset
to Thiram
Species
Aculc To\icil\
C hronic T<»\icil\
u>5„
Aculc Orsil
li»\ici(\
(MKII)>
5-d;i\
LCS",
(ppm)
Suhiiculc
Dicliin
To\icil\
(MUID)
NOAM/I.
OAI.C
(ppm or
m»/k»/
dm)
(MUID)
AITcclcd
r.ii(l|M tints
Bobwhite quail
(iColinus virginicus)
--
--
3,950
slightly toxic
(022923)
500/2,500
(436125-02)
reduced numbers
of eggs hatched,
reduced survival
Mallard duck
(Anas platyrhynchos)
>2,800
PPm
practically
nontoxic
(Baothl03)
5,000
slightly toxic
(022923)
9.6/39.7
(45441201)
reduced numbers
of eggs hatched,
reduced survival
Honey bee
(Apis meliferus)
73.7
Hg/bee
practically
nontoxic
(0003635)
--
--
--
--
Laboratory rat
(Rattus norvegicus)
2,600
mg/kg
(00153548)
--
--
1.9/3.9
mg/kg/day
body weight
Based on the ecological effect studies, thiram is moderately to very highly toxic to freshwater
and estuarine fish on an acute basis (96-hour LC50's 42 to 7 ppb). In addition, thiram on an acute basis is
highly toxic to freshwater invertebrates (EC50: 210 ppb) and very highly toxic to marine/estuarine
invertebrates (EC50: 3.6 ppb). The level of concern for risk to aquatic plants is not exceeded.
The Agency has required that chronic toxicity testing be conducted for freshwater and
marine/estuarine fish and invertebrates. This chronic toxicity data has not yet been submitted.
Therefore, the Agency cannot determine the chronic toxicity to aquatic organisms.
Table 9. Summary of Acute Aquatic Animal Toxicity Estimates Using Technical Grade Thiram
Species
Aculc To\icil\
Chronic To\icil\
%-lir I.C
(ppl>)
4S-hrl.C 5„
(111^/1.)
Aculc To\icil\
(MUID)
NOAI-X'/
I.OAM
(inii/l.)
Alleclcd l.ndpoinis
(MUID)
Bluegill Sunfish
(Lepomis
macrochirus)
42
--
very highly toxic
(070801)
-
-
Water flea
(Daphnia magna)
--
0.21
highly toxic
(164662)
-
-
Mysid
(Americamysis bahia)
3.6
very highly toxic
(424883-01)
22
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Species
Aculc l <»\ici(\
Chronic T<>\icil\
%-lir I.C
(ppl>)
4X-hrl.( 511
(mj>/l.)
Aculc T«»\icil\
(MKID)
NOAI.C /
I.OAI.C
(in»/l.)
Allcclcd l.ntlpoinis
(MKID)
Eastern oyster
(Crassostrea gigas)
4.7
--
very highly toxic
(424883-01)
--
--
Toxicity data for aquatic plants were submitted because thiram has the potential to reach surface
water from runoff, spray drift, or direct application. The results are provided in Table 10.
Table 10. Summary of Acute Phytotoxicity Data for Aquatic Plants Exposed to Thiram
Species
Aculc To\icil\
%-lir I.C 5ii
Aculc To\icil\
(MKID)
Duckweed
(.Lemna gibba)
1.6 mg a.i/L
(45441202)
Selenastrum capricornutum
0.14 ppm
(44086101)
3. Ecological Risk Calculations
Risk characterization integrates the results of the exposure and ecotoxicity data to evaluate the
likelihood of adverse ecological effects by using risk quotients (RQs). RQs are calculated by dividing
exposure estimates by acute and chronic ecotoxicity values:
RQ = Exposure/Toxicity
RQs are then compared with OPP's levels of concern (LOCs). LOCs are used by OPP to
analyze potential risk to nontarget organisms and the need to consider regulatory action. The criteria
indicate that a pesticide used as directed has the potential to cause adverse effects on nontarget
organisms. Risk presumptions, along with the corresponding LOCs are summarized in Table 11. The
ecotoxicity test values (measurement endpoints) used in the acute and chronic risk quotients are derived
from required studies.
23
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Table 11. Risk Presumptions for Animals and Plants
Kisk Presumption
IOC
lerreslriiil
iininiiils
IOC
ii<|iiiilic
iininiiils
I.OC
plilllls
4cute Risk
There is potential for acute risk; regulatory action may be warranted in
addition to restricted use classification
0.5
0.5
1.0
Acute Restricted Use
There is potential for acute risk, but may be mitigated through restricted
classification
0.2
tse
0.1
NA
Acute Endangered Species
Endangered species may be adversely affected; regulatory action may be
warranted
0.1
0.05
1.0
Chronic Risk
There is potential for chronic risk; regulatory action may be warranted
1
1
NA
4. Ecological Risk Profile
The Agency's ecological risk assessment compares toxicity endpoints from ecological toxicity
studies to estimated environmental concentrations (EECs) based on environmental fate characteristics
and pesticide use data. To evaluate the potential risk to nontarget organisms from the use of thiram
products, the Agency calculates a Risk Quotient (RQ), which is the ratio of the EEC to the most
sensitive toxicity endpoint values, such as the median lethal dose (LD50) or the median lethal
concentration (LC50). These RQ values are then compared to the Agency's levels of concern (LOCs)
which indicate whether a chemical, when used as directed, has the potential to cause adverse effects on
nontarget organisms. When the RQ exceeds the LOC for a particular category, the Agency presumes
that a potential risk of concern exists for that category of organisms.
a. Risk to Birds
(For a complete discussion, see the Ecological Risk Assessment.)
Birds in the field may be exposed to thiram by ingesting treated seeds, grass, broadleaf plants,
small and large insects, fruits, pods, or by other routes, such as incidental ingestion of contaminated soil,
dermal contact with treated seed or foliar surfaces and soil during activities in the treated areas, preening
activities, inhalation of pesticide vapor and contaminated particulate, and ingestion of drinking water
contaminated with the pesticide. This assessment primarily focuses on the four foliar uses mentioned
above because these uses involve substantially higher applications rates than the seed and animal
repellent uses.
Thiram is practically nontoxic to birds (LD50 >2,800 mg/kg) from core studies on an acute
exposure basis. However, chronic exposure can result in reproductive effects in birds. In a chronic
mallard duck feeding study, exposure to thiram resulted in reduced numbers of eggs hatched and
reduced survival of hatchlings with the no observable adverse effect concentration (NOAEC) of 9.6
24
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mg/kg of diet. Chronic LOCs (RQ > 1.0) were exceeded for birds at the maximum seed treatment and
maximum foliar application rates for all uses evaluated (RQ range: 15 to 1,236).
The level of concern is exceeded for acute risk to birds for foliar and turf uses (Table 12), and
the LOC is exceeded for acute restricted risk to birds for use on seeds (Table 13). Table 12 includes RQ
values based on mitigated reduced application rates, reduced number of applications, and increased time
interval between applications (in parentheses). In addition, the level of concern is exceeded for chronic
risk to birds for foliar, turf, and seed uses. The Agency concludes that although thiram exposure from
the seed uses may not be continuous or recurring, chronic effects to birds may occur as a result of initial
exposure to planted seeds. Furthermore, the chronic risk to birds for any of the uses can only be
partially assessed because the chronic toxicity data requirements for birds is only partially fulfilled.
While the RQs exceed the chronic LOC by as much as 1,236-fold, there are a number of
reasons why this might be an overstatement of the risk. Thiram should diffuse out of the seed coat and
into the soil to some extent which will reduce the concentration. While the chronic avian risk is above
the level of concern in this screening assessment, risks may actually be lower if the duration of exposure
is short as a result of dissipation processes and birds relying on other food sources in untreated areas.
Table 12. Summary of Acute and Chronic Avian RQ Values Based on an Adjusted Avian Acute
LQn and Chronic NOAEC of 3,950 ppm and 9.6 ppm of Diet, Respectively
Crop
Appl. Ksilc (llts.
ii.i./A)/# of
iippl./l'ri'(|iR'iic\ nl'
0.2), and acute endangered species LOC (RQ>0.1)
d Exceeds chronic risk (RQ >1.0) level of concern
Usual planting practice is to plant the seed one-half to one inch deep in the soil. This
practice reduces exposure, and thus risk. In addition, the RQs are based on the maximum seed
treatment and foliar application rates and maximum seed planting rates. Not all seeds are treated at the
highest application rate nor are all seeds planted at the highest rate.
Table 13. Acute and Chronic Risk Quotients Calculations for Birds for Seed Uses Only
25
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CiiiHi-iilmliiin nl'
I'liir:iin ;is ivsidiii- mi
IIV;iU'(l Mills (ppill)
ppiii
\().\l".( ppm
.Willi- KQ'd l C/IA ;,,)
(linink
KQll.lA /\().\l.( )
1 nnn
To™
n?.s
104
*RQ = EEC (ppm)/LD50 (mg/kg)* % Body Weight Consumed
b. Risk to Mammals
(For a complete discussion, see the Ecological Risk Assessment.)
Mammals in the field may be exposed to thiram by ingesting treated seeds, grass, broadleaf
plants, small and large insects, fruits, pods, or by other routes, such as incidental ingestion of
contaminated soil, dermal contact with treated seed or foliar surfaces and soil during activities in the
treated areas, preening activities, inhalation of pesticide vapor and contaminated particulate, and
ingestion of drinking water contaminated with the pesticide. This assessment primarily focuses on the
four foliar uses mentioned above because these uses involve substantially higher applications rates than
the seed and animal repellent uses.
Table 14. Mammalian (Herbivore/Insectivore) Acute and Chronic Risk Quotients for Application
of Thiram on Wheat Seed Uses Based on a Rat Acute LDS0 of 2,600 and a Rat Chronic NOAEL of
1.9 mg/kg
CiiiHi-iilmliiin ;is
Ki-sidik- mi Si-i'd
(ppni)
»lld>
\\i-i»hl
" Ii...
K;il ( lironk
\().\r.C (1.')
m»/k»/d;i> ) imiw-rU-d
In ppm)
Auilc
KQ1
('liriink' KQ
1,000
15
95
2,600
38
0.36
24.97
35
66
2,600
38
0.25
17.35
1000
15
2.600
38
0.06
3.94
Although the acute risk quotients indicate that thiram presents an acute restricted use to
mammals for the seed uses (Table 14 above) and an acute risk to mammals (Table 15 below) for the
foliar uses the Agency concludes that the acute risk to mammals is uncertain. This conclusion is based
on the fact that lab studies indicate low toxicity to mammalian species, and that thiram is marketed as an
animal repellent to protect treated seeds or foliage against mammals. This repellency may prevent
wildlife from oral consumption of concentrations high enough to warrant a concern for acute risk, if
multiple seed ingestions are required for a lethal acute dose. Table 15 includes figures in parentheses
for RQ values based on mitigated reduced application rates, reduced number of applications, and
decreased frequency of applications.
Table 15. Summary of Acute and Chronic Mammalian RQ Values Based on an Adjusted
Mammalian Acute LDS0 and Chronic NOAEL of 2,600 mg/kg and 1.9 mg/kg of Diet, Respectively
26
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Crop
Appl. Ksilc (llts.
ii.i./A)/#<»r
iippl./l'ri'(|iR'iic\ nl'
0.2), and acute endangered species LOC (RQ>0.1)
d Exceeds chronic risk (RQ > 1.0) level of concern.
c. Risk to Aquatic Animals
(For a complete discussion, see the Ecological Risk Assessment.)
Exposure to non-target aquatic animals may occur through spray drift and runoff from adjacent
treated sites. The environmental fate database for thiram is incomplete. However, based in part on
supplemental fate data, thiram that is applied foliarly is expected to be sufficiently mobile and persistent
in some cases to reach surface waters in concentrations high enough to impact aquatic life.
Although the major agricultural use of thiram is as a seed treatment, it is the orchard and turf
uses which present the most significant potential risks to endangered and non-endangered aquatic
organisms (freshwater and marine/estuarine fish, invertebrates, plants and algae) on an acute basis. This
is in part because the application rate of the pesticide to the environment (in terms of lbs./acre) is
substantially higher than that for treated seed. In addition to the higher application rate, the orchard and
turf uses typically entail multiple applications, unlike seed, which is only "applied" to the environment
at planting. A higher application rate means potentially higher thiram concentrations in receiving waters
such as low-order streams draining agricultural areas. This explains the level of concern exceedances
for acute risk to aquatic organisms from thiram usage on apples and turf. Typical agricultural practices
for growing strawberries treated with thiram could increase the risk of thiram entering adjacent aquatic
organism habitats. These typical practices include using multiple applications (15 applications at 3.3
lbs. ai/acre), and growing strawberries in plastic-mulch beds. Risks of aquatic habitat contamination
exist from these specific practices because the plastic surface underlying the mulch beds will decrease
rain infiltration and increase runoff from the site of application. Multiple seasonal applications also
increase the probability that thiram could enter water bodies at concentrations high enough to cause
adverse effects to aquatic organisms.
27
-------
The chronic toxicity data requirements for aquatic organisms have not yet been fulfilled.
However, since thiram is moderately to very highly toxic to aquatic organisms on an acute basis, has
adverse reproductive effects on other organisms, and is expected to reach surface waters and persist,
EPA assumes thiram may pose an adverse chronic risk to aquatic organisms.
Below is a summary of the exceedances of the level of concern for acute risks to aquatic
organisms (freshwater and estuarine/marine fish, invertebrates, plants and algae) for thiram usage. This
summary is based on calculated risk quotients and only applies to thiram usage on non-residential turf,
apples, and cotton. (See Section in Integrated Risk Characterization).
EPA has required the chronic studies, fish full life cycle test (Guideline 72-5), and the aquatic
invertebrate life-cycle test (guideline 72-4) using the TGAI of thiram. These studies have not yet been
submitted. However because of the adverse acute risk expected for aquatic organisms, and of the
chronic adverse effects to mammals and birds, EPA assumes high potential chronic risk to aquatic
organisms (including endangered species).
Freshwater Fish
The acute freshwater fish risk quotients are calculated below.
Table 16. Acute Risk Quotients for Freshwater Fish Based on a Bluegill Sunfish
Leopmis macrochirus) LQn o
' 42 ppb
Site/
Application Method
11
(ppb)
Kir
Initial/
Peak
(ppb)
Acute RQ
iire/i e. i
Turf/ground
42
100A
2.2B
Apples/aerial foliar application
42
24A
0.57s
Cotton/seed aDDlication
42
0.036A
< 0.05c
Tier II Surface Water EECs for thiram ftig/L).
Exceeds the level of concern of acute risk to freshwater fish (including endangered species).
C
Does not exceed the level concern.
Freshwater Invertebrates
The freshwater invertebrates acute risk quotients are tabulated below.
Table 17. Acute Risk Quotients for Freshwater Invertebrates Based on a Water Flea (Daphnia
magna) LC^,, of 210 ppb
Site/ Application Method
I(ppb)
NX' Initial/Peak (ppb)
Acute RQ ilTC/I ('. i
Turf/ground
210
100A
0.48B
Apples/aerial foliar application
210
24A
0.11B
Cotton/seed application
210
0.036A
< 0.05c
28
-------
Tier II Surface Water EECs for thiram (jig/L).
Exceeds the level of concern of acute risk to freshwater fish (including endangered species).
C
Does not exceed the level concern.
Estuarine and Marine Fish
The estuarine and marine fish acute risk quotients are tabulated below.
Table 18. Acute Risk Quotients for Estuarine and Marine Fish Based on a Sheepshead minnow
i Cvprinodon variegatus) LCS(
of 540 ppb
Site/
Application Method
I.C,„
(ppb)
1 :i:C Initial/Peak
(ppb)
Acute RQ
iire/i e. i
Turf/ground
540
100A
0.19 B
Apples/aerial foliar application
540
24A
< 0.05B
Cotton/seed application
540
0 036A
<0 05B
Tier II Surface Water EECs for thiram ftig/L).
Exceeds the level of concern of acute risk to freshwater fish (including endangered species).
C
Does not exceed the level of concern.
Estuarine and Marine Invertebrates
The estuarine and marine fish acute risk quotients are tabulated below.
Table 19. Acute Risk Quotients for Estuarine/Marine Aquatic Invertebrates Based on a Mysid
Shrimp LC50 of 3.6 ppb
Site/
Application Method
I.C,„
(ppb)
i:i:c
Initial/Peak
(ppb)
Acute RQ
iire/i e. i
Turf/ground
3.6
100A
28B
Apples/aerial foliar application
3.6
24A
6.7B
Cotton/seed application
3.6
0.036A
< 0.05c
Tier II Surface Water EECs for thiram (jjg/L).
Exceeds the level of concern of acute risk to freshwater fish (including endangered species).
C Does not exceed the level of concern.
d. Risk to Aquatic Plants
(For a complete discussion, see the Ecological Risk Assessment.)
Exposure to non-target aquatic plants may occur through runoff from adjacent treated sites.
Based on environmental concentrations in surface water, no acute LOCs are exceeded for aquatic plants.
No chronic toxicity data were available for the Agency to review and based on the use pattern, no
chronic exposure for aquatic plants is expected.
29
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The aquatic plant risk assessment was performed using the surrogate duckweed Lemna gibba.
The non-vascular acute risk assessments uses either algae or a diatom, whichever is the most sensitive
species. An aquatic plant risk assessment for acute- endangered species is usually made for aquatic
vascular plants from the surrogate duckweed Lemna gibba and Selena strum Capricornutum. Runoff is
computed from environmental concentrations estimated using the GENEEC 2.0 model. The risk
quotient is determined by dividing the pesticide's initial or peak concentration in water by the plant EC50
value. Based on the results of this analysis, no acute levels of concern (RQ >1.0) are exceeded for
aquatic plants. The aquatic plant acute risk quotients are tabulated below.
Table 20. Acute Risk Quotients for Aquatic plants Based on a Selenastrum capricornutum ECS0 of
Site/
Application Method
i
(PPb:
Selena
slnim
( 'apricormi
lumj
i
(PPb:
Lemma
(iihha)
i -:i :c
Initial/Peak
(ppb)
Acute RQ
iire/i e. i
Acute RQ U.emma (iibba:
Aquatic Vascular Plants)
Turf/ground
140
1600
100A
< lc
< 1 c
Apples/aerial foliar
application
140
1600
24A
< lc
< 1 c
Cotton/seed aDDlication
140
1600
0.036A
< lc
< 1 c
A Tier II Surface Water EECs for thiram (|ig I,).
Exceeds the level of concern of risk .
C Does not exceed the level concern.
e. Risks to Endangered Species
(For a complete discussion, see the Ecological Risk Assessment.)
The Agency has developed the Endangered Species Protection Program to identify pesticides
whose use may cause adverse impacts on endangered and threatened species, and to implement
mitigation measures that address these impacts. The Endangered Species Act requires federal agencies
to ensure that their actions are not likely to jeopardize listed species or adversely modify designated
critical habitat. To analyze the potential of registered pesticide uses to affect any particular species,
EPA puts basic toxicity and exposure data developed for REDs into context for individual listed species
and their locations by evaluating important ecological parameters, pesticide use information, the
geographic relationship between specific pesticide uses and species locations, and biological
requirements and behavioral aspects of the particular species. A determination that there is a likelihood
of potential impact to a listed species may result in limitations on use of the pesticide, other measures to
mitigate any potential impact, or consultations with the Fish and Wildlife Service and/or the National
Marine Fisheries Service as necessary.
Thiram's usage on apples, peaches, strawberries, and non-residential turf may potentially present
risk to numerous non-target organisms including endangered species. As discussed above, Agency
estimates of exposure indicate potential risks of reproductive effects to endangered species of birds.
The foliar and turf uses of thiram may pose an acute risk to endangered fish and invertebrate species,
and a chronic risk to endangered bird species. The seed treatment use of thiram may pose a risk to an
30
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endangered seed-eating bird species, the Attwater's Greater Prairie Chicken, which inhabits Texas
where thiram may be used as a seed treatment. The Agency has chosen the Attwater's Prairie Chicken
as a representative granivore to examine. Relating to any additional endangered species concerns, these
findings are based solely on EPA's screening level assessment and do not constitute "may affect"
findings under the Endangered Species Act.
Endangered Aquatic Species
As discussed above, the Agency has determined that the foliar (including uses on apples,
strawberries, and peaches) and turf uses of thiram may pose a risk to endangered fish and invertebrate
species. The Agency does not have data on where thiram is used on peaches and turf; therefore, the
Agency cannot specify which endangered aquatic organisms may be at risk from the peach and turf uses
of thiram. The Agency does however have use location data provided by the USDA, National
Agricultural Statistics Service Agricultural (NASS) Chemical Use Database for the strawberry and
apple uses of thiram. There are counties where USDA census data confirms thiram's major use
locations in recent years up until year 2002 and the possible endangered species which inhabit the
counties and which may be at risk of exposure to thiram from the uses. The endangered species list was
generated by the EPA OPP Endangered Database (ENDANGERED). The endangered species
determined to be at risk of exposure are based on a preliminary endangered species assessment. A more
refined endangered species analysis will be needed to determine the likelihood of endangered species
risk from thiram's foliar and turf uses. In addition, this preliminary endangered species assessment only
represents the major use areas of thiram. There may be other areas in the U.S. where thiram is used.
The Agency does not have data on such areas and therefore, can't assess the potential risk to any
endangered species inhabiting these areas.
Endangered Mammalian Species Risk from Foliar Use
The Agency determined that thiram's foliar uses may present a risk by minimizing the food
sources of small mammals. The foliar uses may contaminate food sources with thiram residue levels
that would prevent consumption. Furthermore, the core mammalian chronic toxicity test demonstrated
that small mammals may be repelled from consuming thiram treated feed. The study showed that when
rats are given a diet of 0, 25, 50 and 150 ppm of thiram treated feed, the animals significantly decreased
their feed consumption at the two highest concentrations. This is an indication that the highest
concentrations of thiram treated feed in the study repelled the rats from consuming the feed. The ELL-
FATE model predicts that the thiram foliar uses at their maximum use rates will contaminate small
mammalian food items with residue levels of 145 to 11,847 ppm. Because of the apparent repellency
affects of thiram, the Agency presumes that small mammals may avoid consumption of the thiram
tainted food items. Consequently, the food supply of these small mammals could be significantly
restricted. Many small mammals have very small foraging territories, and may not be likely to migrate
and find alternate food sources.
The Agency generated a list of endangered species which inhabit counties where USDA census
data confirms thiram's use. The Agency does not have use data on the turf and peach use locations of
thiram; therefore, the Agency cannot determine which endangered mammalian species may be at risk
from the thiram turf and peach uses. Based on the USDA NASS of the apple and strawberry uses, the
strawberry use sites in California are the only use sites where thiram may pose a risk to endangered
mammals. This is based on the dietary habits of these endangered mammals in California. Because of
the apparent mammalian repellency characteristics (discussed above), the Agency presumes that small
31
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mammals may avoid consumption of thiram tainted mammalian food items (i.e. insects, and nontarget
plants). Consequently, their food sources may be restricted. This is because these small mammals have
small foraging territories, and may not likely migrate and find alternate food sources. Thus, the Agency
presumes that endangered mammals may be indirectly adversely affected by thiram's strawberry use
because it may restrict potential food sources. These conclusions on mammalian endangered species
risks are based on an a preliminary screening analysis. A more refined endangered species analysis will
be needed to determine the likelihood of endangered species risk from thiram's foliar use.
Endangered Avian Species from Foliar and Turf Uses
The Agency has determined that the foliar and turf uses of thiram may pose a risk of causing
adverse reproductive effects in endangered birds. This conclusion is based on several premises. The
first premise is that the risk quotients indicate that the foliar uses of thiram may cause avian food item
contamination that will exceed the Agency level of concern for causing reproductive effects in birds.
Another premise for the Agency's conclusions is that even though thiram is marketed as an animal
repellent, results of laboratory studies indicate birds may ingest enough thiram-treated feed to cause
adverse reproductive effects. A core reproductive toxicity study demonstrated that mallard ducks
ingested a sufficient amount of treated feed (39.7 ppm) to cause significant reproductive impairments in
birds. The reproductive effects were reductions in embryo development, hatchling survival and number
of eggs hatched. In addition, the thiram task force submitted two supplemental laboratory studies
testing the avian repellency of thiram. The studies demonstrated that when birds are given an option
between untreated feed and thiram treated feed birds prefer the untreated feed; however, they will
consume the treated feed in quantities shown to cause adverse reproductive effects. In conclusion,
because of the risk quotient calculations and the laboratory tests discussed above, the Agency concludes
that thiram's foliar and turf uses may pose a risk of causing adverse reproductive effects in wild bird
species including endangered species.
The Agency does not have data on where thiram is used on peaches and turf; therefore, the
Agency cannot specify which endangered avian organisms may be at risk from the peach and turf uses
of thiram. The Agency does however have use location data provided by the USDA, National
Agricultural Statistics Service Agricultural Chemical Use Database for the strawberry and apple uses of
thiram. There are counties where USDA census data confirms thiram's major use locations in recent
years up until year 2002 and the possible endangered species which inhabit the counties and which may
be at risk of exposure to thiram from the uses. The endangered species list was generated by the U.S.
EPA OPP Endangered Database (LOCATE). The endangered species determined to be at risk of
exposure are based on a preliminary screening level endangered species assessment. A more refined
endangered species analysis will be needed to determine the likelihood of endangered species risk from
thiram's foliar use. In addition, this preliminary endangered species assessment only represents the
major use areas of thiram. There may be other areas in the US where thiram is used. The Agency does
not have data on such areas and therefore cannot assess the potential risk to any endangered species
inhabiting these areas.
Endangered Avian Species Risk from Seed Treatments
The Agency determined that there is an endangered seed eating bird species, the Attwater's
Prairie Chicken, that inhabits Texas where thiram may be used as a seed treatment. Based on
information provided by the U.S. Fish and Wildlife Service, the endangered species profile, and
communications with refuge managers, the Attwater's Prairie Chicken may be at risk for consuming
32
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unacceptable levels of thiram-treated seed. The seed foraging behavior of the Attwater's Prairie
Chicken, combined with the fact that seed planted in the vicinity of this endangered species are typically
incorporated at depths where the chicken is not likely to encounter the treated seed, reduces the
likelihood of exposure and risk.
Attwater's Prairie Chicken
The Agency has chosen one species, the Attwater's Prairie Chicken as a representative
granivore to examine. Relating to any additional endangered species concerns, these findings are based
solely on EPA's screening level assessment and do not constitute "may affect" findings under the
Endangered Species Act.
The Attwater's Prairie Chicken was formerly located throughout Gulf Coast prairies of
southwestern Louisiana and Texas, south to the Nueces River. Today, only two geographically
separated small populations totaling approximately 62 individuals remain.
Properly managed coastal prairie grassland, characterized by diversity of vegetation, satisfies
every known requirement of Attwater's Prairie Chicken. The bird uses shorter grasses for courtship and
feeding, and tall grasses for nesting, feeding, and loafing. The chicken also uses fallow rice fields and
other combinations of pasture and croplands. Courtship areas ("booming grounds") may be natural
grassy flat with low vegetation, or artificially maintained surfaces such as little-used roads, airport
runways, or oil well pads. The birds nest typically in tall grasses.
According to the U.S. Fish and Wildlife Service's recovery plan, the primary threat to the bird's
existence is loss, fragmentation, and degradation of coastal prairie habitat, which has been converted to
rice cultivation or over-grazed and invaded by brush. Residential and urban development, and oil and
gas development also contributed to the habitat loss. Other possible threats include: increased predation
as a result of habitat fragmentation, disease, catastrophic weather events, inbreeding, and red imported
fire ants.
Although the Attwater's Prairie Chicken has been observed in sorghum, cotton, soybean and
peanut crops on or near mating display sites during planting and in fallow rice fields; the birds were
apparently not exposed to lethal levels of the pesticides typically used in their vicinity. Pesticides were
not determined to affect the endangered prairie chicken in Texas since no mortalities of the chicken
could be directly attributed to pesticides (in terms of tissue residues) during the three-year study period
(1978 to 1980) .
Currently, the vast majority of Attwater's Prairie Chickens are contained on two reserves in
Texas, the Attwater Prairie Chicken National Wildlife Refuge (APCNWR) and The Nature
Conservancy's Texas City Preserve (TCP). According to reserve managers in Texas (pers. comm: T.
Rossignol, APCNWR manager, and B. Crawford, TCP reserve manager; 8/17/04), the ACPNWR
contains approximately 40 birds and is directly surrounded by agricultural fields, mainly rice with a
small amount of cotton. The female birds are known to travel no more than one mile off of the refuge
during the time frame when thiram could pose a risk of reproductive effects. Adult prairie chicken diets
consist primarily of foliage, exceeding seeds and insects in all seasons. Greatest seed and insect
consumption by adults occurs in autumn. Diets of young birds consist primarily of insects. The
chickens weigh from one and a half to two pounds. According to the reserve managers, the potential for
the chickens to ingest treated seeds is present, however the potential would be greatly reduced if the
33
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birds had to dig for the seeds since the prairie chicken does not typically dig for seeds. The greatest risk
of ingesting treated seeds would likely result from spilled seeds left on the ground's surface.
The Texas City Preserve is surrounded by grazing pastures and industry. Containing
approximately 22 birds that are not known to venture far from the preserve, the risk of agricultural
exposure is minimal. Therefore, the main concern would be for the birds contained on the APCNWR.
As noted by the refuge managers, cotton is grown to a limited extent in the vicinity of the
reserves; however, treated cotton seed will be incorporated to a depth of at least one inch. Based on
seeding practices and the fact that the prairie chicken does not typically dig for food, the likelihood of
exposure to thiram-treated seed is low.
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IV. Risk Management, Reregistration, and Tolerance Reassessment Decision
A. Determination of Reregistration Eligibility
Section 4(g)(2)(A) of FIFRA calls for the Agency to determine, after submission of relevant
data concerning an active ingredient, whether or not products containing the active ingredient are
eligible for reregistration. The Agency has previously identified and required the submission of the
generic (i.e., active ingredient-specific) data required to support reregistration of products containing
thiram as an active ingredient. The Agency has completed its review of these generic data, and has
determined that the data are sufficient to support reregistration of all supported products containing
thiram.
The Agency has completed its assessment of the dietary, occupational, residential, and
ecological risk associated with the use of pesticide products containing the active ingredient thiram.
Based on a review of these data and on public comments on the Agency's assessments for the active
ingredient thiram, the Agency has sufficient information on the human health and ecological effects of
thiram to make decisions as part of the tolerance reassessment process under FFDCA and reregistration
process under FIFRA, as amended by FQPA. The Agency has determined that thiram containing
products are eligible for reregistration provided that: (i) current data gaps and confirmatory data needs
are addressed; (ii) the risk mitigation measures outlined in this document are adopted; and (iii) label
amendments are made to reflect these measures. Label changes are described in Section V. Appendix
A summarizes the uses of thiram that are eligible for reregistration. Appendix B identifies the generic
data requirements that the Agency reviewed as part of its determination of reregistration eligibility of
thiram, and lists the submitted studies that the Agency found acceptable. Data gaps are identified as
generic data requirements that have not been satisfied with acceptable data.
Based on its evaluation of thiram, the Agency has determined that thiram products, unless
labeled and used as specified in this document, would present risks inconsistent with FIFRA.
Accordingly, should a registrant fail to implement any of the risk mitigation measures identified in this
document, the Agency may take regulatory action to address the risk concerns from the use of thiram. If
all changes outlined in this document are incorporated into the product labels, then all current risks for
thiram will be adequately mitigated for the purposes of this determination.
B. Public Comments and Responses
Through the Agency's public participation process, EPA worked with stakeholders and the
public to reach the regulatory decisions for thiram. During the public comment period on the risk
assessments, which closed on August 31, 2004, the Agency received comments from the following
commentors, Gustafson, National Cotton Council, the U.S. Golf Association, the Golf Course
Superintendents of America, VJP Consulting, the American Sugarbeet Association, Taminco, the
Southern Minnesota Beet Sugar Cooperative, Seminis Vegetable Seeds, Inc., Beta Seed, Inc., Southern
Forest Nursery Management Cooperative, Cleary Chemical Corporation, the California Strawberry
Commission and the Minnesota Golf Course Superintendents Association. These comments in their
entirety are available in the public docket, http://docket.epa.gov/edkpub/index.jsp. (OPP-2004-0183).
C. Regulatory Position
1. Food Quality Protection Act Findings
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a. Determination of Safety to U.S. Population
As part of the FQPA tolerance reassessment process, EPA assessed the risks associated with
thiram. The Agency has determined that the established tolerances for thiram, with amendments and
changes as specified in this document, meet the safety standards under the FQPA amendments to
section 408(b)(2)(D) of the FFDCA, and that there is a reasonable certainty no harm will result to the
general population or any subgroup from the use of thiram. In reaching this conclusion, the Agency has
considered all available information on the toxicity, use practices and exposure scenarios, and the
environmental behavior of thiram.
The Agency has worked with the registrant Taminco to reduce potential exposure to thiram
treated strawberries and apples. As a result, Taminco has requested voluntary cancellation of thiram use
on apples and will amend its registration to remove strawberries from its label pending Agency receipt,
review, and acceptance of additional data (a strawberry processing study and a Developmental
Neurotoxicity Study) and reevaluation of risks. Peaches are the only remaining food commodity in the
risk cup. Considering that peaches are a low contributor (<9% of the aPAD), the acute dietary risks are
not of concern to the Agency.
Acute risks from aggregate exposures are not of concern. Models have been used to estimate
ground and surface water concentrations. The DWLOCs calculated to assess the surface water
contribution to acute (noncancer) dietary exposure range from 1750wg/L (for the U.S. general
population) to less than 500wg/L (infants and children). The surface water EEC (47.8ppb) is
significantly less than the acute DWLOC. The groundwater EEC (0.84) is also significantly less than
the acute DWLOC. These DWLOCs were calculated assuming no exposure from food in order to
evaluate potential acute risk posed by drinking water alone. However, if dietary exposure due to peach
consumption had been included in the DWLOC calculations, the LOCs would have been only
approximately 10% lower, i.e., the lowest DWLOC would have been 450wg/L. Thus, the Agency
concludes with reasonable certainty that aggregate exposure to food and drinking water will not result in
an unacceptable acute risk.
Short-term aggregate risks are not of concern. DWLOCs were calculated based upon average
food residues and the residential post-application exposure scenario(adult golfers). Because the inputs
to calculate short-term aggregate risks are very low (cPAD=2.8% and the MOE at day 0 for golfers is
794), the Agency concludes with reasonable certainty that aggregate exposure to food, drinking water
and residential exposures will not result in an unacceptable risk.
Chronic risks from aggregate exposures are not of concern. The DWLOC calculated to assess
the surface water contribution to chronic (noncancer) dietary exposure is a range from 48.30wg/L (for
the U.S. general population) to less than 10.80wg/L (infants and children). The surface water EEC (4.3
ppb) is less than the chronic DWLOC, indicating that chronic exposure to thiram in food and drinking
water from surface water sources is below the Agency's level of concern. The groundwater EEC (0.84
ppb) is also less than the chronic DWLOC, indicating that chronic exposure to thiram in food and
drinking water from groundwater sources is below the Agency's level of concern. Since the model-
based estimates for concentrations in surface water and groundwater are below the calculated chronic
DWLOC, the Agency concludes with reasonable certainty that aggregate exposure to food and drinking
water will not result in an unacceptable chronic risk.
b. Determination of Safety to Infants and Children
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EPA has determined that the established tolerances for thiram, with amendments and changes as
specified in this document, meet the safety standards under the FQPA amendments to section
408(b)(2)(C) of the FFDCA, that there is a reasonable certainty of no harm for infants and children.
The safety determination for infants and children considers factors on the toxicity, use practices and
environmental behavior noted above for the general population, but also takes into account the
possibility of increased dietary exposure due to the specific consumption patterns of infants and
children, as well as the possibility of increased susceptibility to the toxic effects of thiram residues in
this population subgroup.
No Special FQPA Safety Factor is necessary to protect the safety of infants and children. In
determining whether or not infants and children are particularly susceptible to toxic effects from thiram
residues, the Agency considered the completeness of the database for developmental and reproductive
effects, the nature of the effects observed, and other information. The FQPA Safety Factor has been
removed (i.e., reduced to IX) for thiram based on: 1) the outcome of the degree of concern analysis that
failed to identify any residual uncertainties, 2) Exposure databases are complete for thiram and the risk
assessment for each potential exposure scenario includes all metabolites and/or degradates of concern
and, 3) The risk assessment does not underestimate the potential risk for infants and children.
The Agency has concluded that a Developmental Neurotoxicity Study (DNT) on thiram is
necessary based on a weight of evidence including: 1) findings of central neurological system defects as
seen in the Developmental Study in rats (MRID 00259810-02); and 2) neurotoxic effects in the Acute
and Subchronic Neurotoxicity Study (MRID 42912401 and 43012701, respectively). Because the
thiram toxicology database does not include a DNT study, a Database Uncertainty Factor is necessary to
be protective of children. This Uncertainty Factor is applied only to exposure scenarios that are
expected for children or pregnant women, and thus is not applied to occupational exposure scenarios.
The Agency has determined the appropriate size of the Database Uncertainty Factor for thiram
by comparing the NOAEL from an acceptable reproduction study with a dose level that the Agency
assumes would be the NOAEL from a DNT study on the subject pesticide if one were available. Thus,
the Agency has assumed that if a DNT study were conducted, the NOAEL from that study would be
similar to the lowest dose tested in the reproduction study. The assumption is based on an analysis of
data from DNT studies previously submitted to the Agency which suggests that NOAELs lower than
the lowest dose tested in the reproduction study are unlikely to occur.
The lowest dose tested in the rat reproduction study was 1.7 mg/kgbw-day. The Agency
therefore has assumed that a DNT study on thiram would yield a NOAEL of approximately 1.7
mg/kgbw-day. The Agency's determination of the size of the Database Uncertainty Factor has been
derived by dividing the point of departure used for each exposure pathway by the assumed DNT
NOAEL of 1.7 mg/kgbw-day. If the point of departure for a particular risk assessment is higher than the
assumed NOAEL, a Database Uncertainty Factor is typically required. If the difference is in the range
of 3X, a 3X factor is used. If it is larger than 3X, a 10X factor is used. If the point of departure is equal
to or lower than the assumed NOAEL, a Database Uncertainty Factor is not required since it is
concluded that the DNT is unlikely to yield a point of departure more sensitive than that currently being
used for that assessment.
Therefore, based on this approach, acute dietary risk estimates will include a Database
Uncertainty Factor of 3X. For chronic dietary risk estimates, no Database Uncertainty Factor is needed
and the target MOEs for all occupational and residential risk assessments will now be 100.
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c. Endocrine Disruptor Effects
EPA is required under the FFDCA, as amended by FQPA, to develop a screening program to
determine whether certain substances (including all pesticide active and other ingredients) "may have an
effect in humans that is similar to an effect produced by a naturally occurring estrogen, or other
endocrine effects as the Administrator may designate." Following recommendations of its Endocrine
Disruptor Screening and Testing Advisory Committee (EDSTAC), EPA determined that there was a
scientific basis for including, as part of the program, the androgen and thyroid hormone systems, in
addition to the estrogen hormone system. EPA also adopted EDSTAC's recommendation that EPA
include evaluations of potential effects in wildlife. For pesticides, EPA will use FIFRA and, to the
extent that effects in wildlife may help determine whether a substance may have an effect in humans,
FFDCA authority to require the wildlife evaluations. As the science develops and resources allow,
screening of additional hormone systems may be added to the Endocrine Disruptor Screening Program
(EDSP).
When the appropriate screening and/or testing protocols being considered under the EDSP have
been developed, thiram may be subject to additional screening and/or testing to better characterize
effects related to endocrine disruption.
d. Cumulative Risks
Risks summarized in this document are those that result only from the use of thiram. The Food
Quality Protection Act (FQPA) requires that the Agency consider "available information" concerning
the cumulative effects of a particular pesticide's residues and "other substances that have a common
mechanism of toxicity." The reason for consideration of other substances is due to the possibility that
low-level exposures to multiple chemical substances that cause a common toxic effect by a common
toxic mechanism could lead to the same adverse health effect as would a higher level of exposure to any
of the substances individually. Unlike other pesticides for which EPA has followed a cumulative risk
approach based on a common mechanism of toxicity, EPA has not made a common mechanism of
toxicity finding for thiram. For information regarding EPA's efforts to determine which chemicals have
a common mechanism of toxicity and to evaluate the cumulative effects of such chemicals, see the
policy statements released by EPA's Office of Pesticide Programs concerning common mechanism
determinations and procedures for cumulating effects from substances found to have a common
mechanism on EPA's website at http://www.epa.gov/pesticides/cumulative/.
2. Tolerance Summary
Tolerances are established for residues of thiram per se under 40 CFR §180.132 in/on apples,
peaches and strawberries. These tolerances are established at 7 ppm. No tolerances have been
established for thiram residues in animal and processed food/feed commodities. The Pesticide
Analytical Manual (PAM) Vol. II lists a colorimetric method, Method I, for the determination of
dithiocarbamate residues in/on plant commodities. Additional methods (Methods H-IV and Method A),
which are based on the decomposition of dithiocarbamates with release of carbon disulfide (CS2), are
also listed in PAM Vol. H These methods are nonspecific for CS2-generating compounds.
a. Tolerances Currently Listed Under 40 CFR §180.301
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Pending label revisions for some commodities, adequate residue data are available to support
the current established thiram tolerances on the following raw agricultural commodities: apples,
strawberries and peaches.
Residue analytical methods for the determination of thiram residues of concern in animal
commodities are not available because tolerances for animal commodities have not been established. If
the requested ruminant feeding study suggests that tolerances in milk and edible tissues of ruminants are
needed, registrants will be required to develop enforcement and data-collection methods capable of
determining thiram residues of concern.
As a result of changes to Table 1 of OPPTS 860.1000, Residue Chemistry Test Guidelines, the
Agency has determined that tolerances on the following commodities are warranted (Table 21).
Following submission of additional data by the registrant (specifically, peach field trial data), EPA
intends to evaluate the data and, if adequate, set appropriate tolerances for peaches. In addition, the
registrant has voluntarily requested cancellation of use on apples. This tolerance will be revoked at a
later date.
Table 21. Tolerance Reassessment Summary for Thiram
(ommodih
Curmil
Tolerance
(ppm)
Tolerance
(ppm)
Comment/
/( or red ( ominotlity Ih'/inilion/
Tolerances Listed Under 40 CFR §180.132
Apples
7
9
[Apple]
Peaches
7
TBD1
[Peach]
Strawberries
7
9
\Strawberrv 1
1) TBD = To be determined. Reassessment of tolerance(s) cannot be made at this time because either additional data or
clarification of proposed use patterns are required.
b. Codex Harmonization
There are no established or proposed Codex MRLs for thiram residues per sc\ however, Codex
limits for dimethyldithiocarbamates fungicides are grouped under dithiocarbamates. Maximum residue
limits (MRLs) for the dithiocarbamates are established for several commodities resulting from the use
of mancozeb, maneb, metiram, propineb, thiram, and ziram and are currently expressed as ppm carbon
disulfide. Harmonization of the U.S. tolerances with Codex MRLs is impractical at the present time. A
numerical comparison of the Codex MRLs and the corresponding reassessed U.S. tolerances is
presented in Table D of the April 17, 2000, Product and Residue Chemistry Chapter for the Thiram
RED Document.
D. Regulatory Rationale
The Agency has determined that thiram is eligible for reregistration provided that additional
required data confirm this decision and that the risk mitigation measures outlined in this document are
adopted, and label amendments are made to reflect these measures.
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The following is a summary of the rationale for managing risks associated with the use of
thiram. Where labeling revisions are warranted, specific language is set forth in the summary tables of
Section V of this document.
1. Human Health Risk Management
a. Dietary (Food) Risk Mitigation
For all supported commodities, the dietary exposure estimates are below the Agency's level of
concern. Therefore, no risk mitigation measures are required to address exposure to thiram residues in
food.
The refined (Tier 3) acute probabilistic dietary exposure and risk estimates at the 99.9th
percentile of exposure is of concern to the general U.S. population and all population subgroups. For
children 1-2 years old, the highest exposed population subgroup, the acute dietary exposure risk
estimate (aPAD) is 334%. Additional analyses are conducted to determine the contribution of each
commodity to the dietary risk. These sensitivity analyses indicate that both strawberries and apples are
significant contributors to the dietary risk for children 1-2 year old.
The Agency has worked with the registrant, Taminco to reduce potential exposure to thiram
treated strawberries and apples. Subsequently, Taminco has requested voluntary cancellation of thiram
use on apples and will amend its registration to remove strawberries from its label pending receipt,
review, and acceptability of additional data (a strawberry processing study and a Developmental
Neurotoxicity Study). The percent of the aPAD considering dietary contributions from strawberries and
peaches only is reduced to 273. Without strawberries, the percent of the aPAD is reduced to 9.
To further reduce dietary concerns, the Agency has determined that the following label changes
for specific scenarios are appropriate and required for reregistration eligibility:
"Treated Seed - Do Not Use for Food, Feed, or Oil Purposes."
b. Drinking Water Risk Mitigation
As previously discussed above, the acute, short-term and chronic risks from aggregate
exposures are not of concern to the Agency and no further mitigation is necessary.
c. Residential Risk Mitigation
Thiram is not available for sale or use by homeowner applicators. As such, all residential risks
were calculated related to the non-residential turf uses that include golfing for adults and toddler
exposures in areas that can be treated with thiram by certified pesticide applicators. MOEs for golfers
are not of concern to the Agency (MOE=764 at Day 0), and therefore no risk mitigation measures are
required to address this scenario.
To protect children from scenarios of concern (MOE= 4) for exposure to thiram treated turf)
and to further protect from exposure to ornamentals treated with thiram as a deer repellent, the Agency
is requiring the following label modifications:
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Deer Repellent Use:
Use one quart of this product in 3 to 7 gallons of water for application to 1000ft2
Applications to ornamentals will be restricted to the following 17 Northern states and
applications will occur during the winter season only (October thru March):
OH, PA, NY, MI, CT, MA, IN, IL, NJ, WV, MN, WI, VT, NH, RI, DE, and
MD.
Cancellations of Turf/Other Uses:
Turf applications to parks, athletic fields and commercial landscapes.
All turf applications for turf grown for sale or other commercial use such as sod.
All homeowner and retail uses on residential lawns and turf
Residential homeowner use as a fungicide on bulbs, flower seeds, greenhouse and
nursery cuttings, and pruning paints.
Through these label amendments and voluntary cancellations to remove all homeowner uses
from Taminco, the Agency believes exposure to the deer repellent use will be insignificant and therefore
not of concern. No additional mitigation is necessary.
d. Occupational Risk Mitigation
1) Handler exposure
Occupational exposure and risk estimates were conducted using maximum application rates and
high-end assumptions for amount of seed treated and planted. A target Margin of Exposure (MOE) of
100 is considered adequate for occupational exposure via dermal and inhalation routes. The results of
the worker exposure assessment indicate that most potential exposure scenarios result in MOEs > the
target MOE of 100 for dermal and inhalation for all of the seed crops treated with thiram products being
actively sold in the U.S.
In most scenarios, MOEs meet or exceed the required target MOE of 100 at some level of
personal protection. For the most part, current label requirements (for personal protection single layer
clothing, gloves, and no respirator) appear to be generally inadequate except for operations where
exposures and/or the amount of chemical used is low. Scenarios where MOEs do not exceed 100 at any
level of personal protection include some loading scenarios for aerial applications, aerial granular
applications, some handheld equipment use, and a few commercial seed treatment scenarios.
Therefore, to reduce worker exposure, the Agency has determined that the following label
changes for specific scenarios are appropriate and required for reregistration eligibility:
Mixers/Loaders/Applicators/Other Handlers CgeneraD: wear baseline (long-sleeve shirt,
long pants, shoes, socks, no respirator) plus chemical resistant gloves for the
following scenarios (mixer/loaders wear a chemical resistant apron):
liquids or dry flowables applied aerially
liquids, dry flowables or sprays applied via airblast
liquids, dry flowables or sprays applied via groundboom
liquids or dry flowables applied via a high pressure handwand
liquids or dry flowables applied for rights of way
liquids applied as a paint-on application
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solid broadcast spreader
repellent paint brush use
sprinkler can
ready-to-use solutions
wettable powder paint-on
dry flowable paint-on
Mixers/loaders/applicators/other handlers (packaged seed): seed that has been treated
with this product that is then packaged or bagged for future use must bear
labeling that contains the restricted-entry interval (REI) information and the
following text on the outside of the seed package or bag: "Persons opening this
bag or loading/pouring the treated seed, must wear long-sleeved shirt, long
pants, shoes, socks, and chemical resistant gloves."
Flaggers: wear baseline (long-sleeve shirt, long pants, shoes, socks, no respirator for the
following scenarios:
sprays applied aerially
In addition to the above mentioned PPE requirements, the registrant has agreed to the following
use modifications/amendments to further address the Agency's concerns:
Cancellation of the aerial and hand/spoon applications
Changing all wettable powder formulations to water soluble bag formulations.
Cancellation of on-farm seed treatment of peanuts
2) Post-Application Risk Mitigation
EPA has determined that the current 24 hour REI is appropriate, and labels must contain the
following language to be eligible for reregistration:
"After the seeds have been planted, do not enter or allow worker entry into treated areas during
the REI of 24 hours. Exception: Once the seeds are planted in soil or other planting media, the Worker
Protection Standard allows workers to enter the treated area without restriction if there will be no
worker contact with the soil/media subsurface."
2. Environmental Risk Mitigation
Although the major agricultural use of thiram is seed treatment, it is the foliar (strawberries,
peaches and apples) and turf uses which present the most significant potential risks to endangered and
non-endangered aquatic organisms (freshwater and marine/estuarine fish, invertebrates, plants and
algae), on an acute basis. This is in part because the application rate of thiram to the environment is
higher than that for treated seed. In addition to the higher application rate, the orchard and turf uses
typically entail multiple applications, unlike seed, which is only "applied" to the environment at
planting. This means higher thiram concentrations in receiving waters such as low-order streams
draining agricultural areas. This explains the level of concern exceedances noted in Chapter 3 for acute
risk to aquatic organisms from thiram usage on apples and turf. The following is a summary of the
aquatic risks:
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Freshwater fish potential risk
acute risk for non-residential turf and apple uses (risk includes endangered species).
• RQs range from 0.11 to 3.43
Freshwater invertebrate potential risk
acute risk for non-residential turf and apple uses (risk includes endangered species).
• RQs range from 0.05 to 0.48
Marine/Estuarine fish potential risk
acute risk to non-residential turf uses (risk includes endangered species)
• RQs range from 0.05 to 0.19
Marine/Estuarine invertebrate potential risk
acute risk for non-residential turf and apple uses (risk includes endangered species).
• RQs range from 0.05 to 28
The Agency is also concerned with the seed, foliar (strawberries, peaches and apples) and turf
uses of thiram and potential risk of causing adverse effects to birds (RQs range from 0.06 to 1,237.
Recalculated RQs based on reduced application rates, number of applications, and frequency of
applications summarized below range from 12-573). These effects can include reproductive
impairments in endangered and non-endangered bird species. This conclusion is based on several
premises. The first premise is that the risk quotients indicate that the foliar uses of thiram may cause
avian food item contamination that will greatly exceed the Agency's level of concern for causing
reproductive effects in birds. Another premise for the Agency's conclusions is that even though thiram
is marketed as an animal repellent, results of laboratory studies indicate that birds may ingest enough
thiram-treated feed to cause adverse reproductive effects. A third premise is that the diet of some bird
species consist largely of seeds (including agriculturally planted seeds). Additionally, the Agency has
concluded that the foliar and turf uses of thiram may pose a risk to endangered bird species. The
Agency looked specifically at the Attwater's Prairie Chicken in Texas which may be at risk for
consuming thiram treated seed and, to be eligible for reregistration, the Agency requires that additional
risk mitigation measures be implemented which are discussed in detail below.
Furthermore, the Agency is concerned with potential risk to mammals (RQs range from 0.01 to
6,249). The Agency has determined that thiram's foliar uses may present a risk by minimizing the food
sources of small mammals. This is because the foliar uses may contaminate their food sources with
thiram residue levels that will prevent consumption. Because of the apparent repellency affects of
thiram, the Agency presumes that small mammals may avoid consumption of the thiram tainted food
items. Consequently, the food supply of these small mammals could be significantly restricted. This is
because many small mammals have very small foraging territories, and they many not be likely to
migrate and find alternate food sources.
To reduce risks to mammals, birds, and aquatic species, the Agency, in agreement with the
technical registrants of thiram, has developed several mitigation requirements to address the above
mentioned concerns. They include:
A statement added to the label "Treated seeds are hazardous to birds and mammals. Do
not plant treated seed by broadcasting to the soil surface. Ensure that all planted
seed are thoroughly covered with soil, especially in turn areas. Plant cotton,
wheat, barley, oats and sugar beet seed a minimum of 1 inch deep. If seeds are
not thoroughly incorporated by the planter during planting, additional
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incorporation may be required to reduce exposed seeds. Clean-up, bury or
cover all spilled seed with soil."
A statement added to the label: "This pesticide is toxic to fish. Do not apply to water,
to areas where surface water is present, or to intertidal areas below the mean
high water mark. Do not contaminate water when disposing of equipment
washwater or rinsate or by disposal of wastes."
Cancellation of thiram use on apples.
Restriction of thiram use on golf courses to tees and greens only.
Reduce the winter golf course treatment from a maximum of four applications to a
maximum of one application.
Reduction of summer golf course treatment from a maximum of eight applications to a
maximum of three applications.
Restrict the number of annual applications of thiram to golf courses to 47 pounds of
active ingredient per acre (this corresponds to a 40% total reduction in thiram
use on golf courses).
For the golf course use, increase the re-treatment interval from 7 to 14 days.
For strawberries, limit the maximum number of applications to five at 2.6 lbs ai/Acre.
For strawberries, East of the Mississippi River, limit the maximum number of
applications to twelve at 2.6 lbs ai/Acre.
For strawberries, add a label statement to indicate that 1.3 lbs ai/Acre should be used
when thiram is used in combination with other fungicides.
For strawberries, the label will establish a 25 foot vegetative buffer zone from water
bodies.
For cotton, reduce the maximum treatment rate for cotton seed from 2.25 oz. ai/cwt
(1406 ppm) when treated with thiram as a single active ingredient to 1.6 oz.
ai/cwt (1,000 ppm) reflecting the global use rate for thiram on imported and
exported cotton seed.
For cotton, reduce the maximum treatment rate for cotton seed for thiram in products
containing multiple active ingredients to 1.0 oz. ai/cwt (625 ppm).
Upon examining the risks and requiring the above listed mitigation measures, the Agency
believes that concerns noted in Chapter 3 and above have been adequately mitigated. No further
mitigation is needed at this time.
3. Other Labeling Requirements
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In order to be eligible for reregistration, various use and safety information will be included in
the labeling of all end-use products containing thiram. For the specific labeling statements and a list of
outstanding data, refer to Section V of this RED document.
4. Endangered Species Considerations
a. The Endangered Species Program
The Agency has developed the Endangered Species Protection Program to identify pesticides
whose use may cause adverse impacts on endangered and threatened species, and to implement
mitigation measures that address these impacts. The Endangered Species Act requires federal agencies
to ensure that their actions are not likely to jeopardize listed species or adversely modify designated
critical habitat. To analyze the potential of registered pesticide uses that may affect any particular
species, EPA uses basic toxicity and exposure data developed for the REDs and considers ecological
parameters, pesticide use information, geographic relationship between specific pesticide uses and
species locations, and biological requirements and behavioral aspects of the particular species.
A determination that there is a likelihood of potential impact to a listed species may result in
limitations on use of the pesticide, other measures to mitigate any potential impact, or consultations
with the Fish and Wildlife Service and/or the National Marine Fisheries Service as necessary.
b. General Risk Mitigation
The endangered species risk mitigation strategies described in this document address risks
associated with thiram as a sole active ingredient. Thiram end use products (EPs) may also contain
other registered pesticides. To address the risks posed by these end use products, the Agency requires
that users adopt all endangered species risk mitigation measures for all active ingredients in the product.
If a product contains multiple active ingredients with conflicting endangered species risk mitigation
measures, the more stringent measure(s) should be adopted.
c. Species-Specific Risk Mitigation
The Agency's initial assessment suggested that many endangered species may potentially be
impacted by thiram. Several of these species are known to consume seeds and may occur near field
crops. As listed in Appendix J of the May 19, 2004, EFED Revised Thiram Environmental Risk
Assessment, many of the endangered species were fish in Washington and Oregon. The Agency
believes that these risks have been reduced since Taminco has requested voluntary cancellation of the
apple use. The Agency then looked at additional species listed and chose The Attwater's Prairie
Chicken as a representative granivore. This species may be at risk for consuming unacceptable levels of
thiram treated seed and, to be eligible for reregistration, the Agency requires that additional risk
mitigation measures be implemented.
Attwater's Prairie Chicken In addition to the general risk mitigation measures discussed above, the
Agency will issue new or revised County Specific Bulletins for the Attwater's Prairie Chicken in
Austin, Colorado, and Galveston Counties in Texas. These bulletins will allow the Agency to
communicate to users the species-specific mitigation measures discussed in this document as well as
any additional or updated measures as necessary. Specifically, the bulletins will prohibit use of thiram-
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treated seed within 1 mile of the US Fish and Wildlife Service's Attwater Prairie Chicken National
Wildlife Refuge and the Nature Conservancy's Texas City Preserve.
County Specific Bulletins currently exist for Austin and Colorado Counties in Texas. These
bulletins address use limitations for aerial and granular pesticide applications, and will be revised to
address seed treatments. A County Specific Bulletin does not exist for Galveston County in Texas and
will be created. The Agency will ensure that the new or revised bulletins for these three counties
include thiram endangered species information before the updated product labels are issued.
To be eligible for reregistration, the Agency requires that the following language be added to
product labels:
"This product may have effects on federally listed threatened or endangered species or their
critical habitat in some counties. It is a violation of federal law to kill, harm or harass listed animal
species without authorization. To limit the potential for such impacts when using this product, consult
and follow the instructions provided in the EPA Endangered Species County Bulletin for the county in
which you are applying the seed. To determine whether your County has a Bulletin consult
http://www.epa.gov/espp before each season's use of this product. Bulletins also may be available from
local pesticide dealers, extension offices, or State pesticide agencies."
In addition, on bag tags this language will be preceded by the following statement: "This bag
contains seed treated with thiram."
EPA plans to require thiram registrants to implement the measures specified above to mitigate
the potential risks to Attwater's Prairie Chicken, an endangered species. As discussed in the Federal
Register notice describing EPA's proposed Endangered Species Protection Program (ESPP), 67 FR
71,49 (December 2, 2002), such risk mitigation measures would be implemented through changes to
pesticide product labeling and county bulletins. Under the ESPP, registrants would amend their
labeling to include a statement requiring users to obtain and follow requirements set forth in a bulletin
developed for affected counties. The restrictions contained in the bulletin would be designed to protect
threatened and endangered species to the extent necessary in each affected county. County bulletins
would be available through EPA's website, as well as through local distribution sources. EPA expects
to finalize its ESPP in the near future, and the risk mitigation measures described in this RED will be
implemented consistent with provisions of the final ESPP.
d. Endangered Species Determination
Attwater's Prairie Chicken: Based on the ecological risk assessment conducted for thiram and
the implementation of the risk mitigation measures described above, EPA has determined that thiram
will have no effect on the Attwater's Prairie Chicken.
Other listed Species: EPA will continue to evaluate whether currently identified and/or
additional endangered species may be impacted by exposure to thiram. The Agency is working with
other federal, state, and local agencies to refine the endangered species risk assessment with the goal of
developing any necessary risk mitigation for endangered species. If in the future specific measures are
necessary for the protection of listed species, the Agency will comply with the requirements in the
consultation regulations promulgated by the US Fish and Wildlife Service and the National Marine
Fisheries Service in 50 CFR Part 402.
46
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V. What Registrants Need to Do
The Agency has determined that thiram is eligible for reregistration provided that: (i) additional
data that the Agency intends to require confirm this decision; and (ii) the risk mitigation measures
outlined in this document are adopted, and label amendments are made to reflect these measures. To
implement the risk mitigation measures, the registrants must amend their product labeling to incorporate
the label statements set forth in the Label Changes Summary Table in Section B below (Table 23). The
additional data requirements that the Agency intends to obtain will include, among other things,
submission of the following:
For thiram technical grade active ingredient products, the registrant needs to submit the
following items:
Within 90 days from receipt of the generic data call in (DCI):
1. completed response forms to the generic DCI (i.e., DCI response form and
requirements status and registrant's response form); and
2. submit any time extension and/or waiver requests with a full written
justification.
Within the time limit specified in the generic DCI:
1. cite any existing generic data which address data requirements or submit new
generic data responding to the DCI.
Please contact Craig Doty at (703) 603-0122 with questions regarding generic reregistration.
By US mail: By express or courier service:
Document Processing Desk (DCI/SRRD) Document Processing Desk (DCI/SRRD)
Craig Doty Craig Doty
US EPA (7508C) Office of Pesticide Programs (7508C)
1200 Pennsylvania Ave., NW Room 266A, Crystal Mall 2
Washington, DC 20460 1801 S. Bell Street
Arlington, VA 22202
For end use products containing the active ingredient thiram the registrant needs to submit the
following items for each product.
Within 90 days from the receipt of the product-specific data call-in (PDCI):
1. completed response forms to the PDCI (i.e., PDCI response form and
requirements status and registrant's response form); and
2. submit any time extension or waiver requests with a full written justification.
Within eight months from the receipt of the PDCI:
1. two copies of the confidential statement of formula (EPA Form 8570-4);
2. a completed original application for reregistration (EPA Form 8570-1). Indicate
on the form that it is an "application for reregistration";
3. five copies of the draft label incorporating all label amendments outlined in
Table 15 of this document;
4. a completed form certifying compliance with data compensation requirements
(EPA Form 8570-34); and
47
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5. if applicable, a completed form certifying compliance with cost share offer
requirements (EPA Form 8570-32); and
6. the product-specific data responding to the PDCI.
Please contact Venus Eagle at (703) 308-8045 with questions regarding product reregistration
and/or the PDCI. All materials submitted in response to the PDCI should be addressed as follows:
By US mail: By express or courier service:
Document Processing Desk (PDCI/PRB) Document Processing Desk (PDCI/PRB)
Venus Eagle Venus Eagle
US EPA (7508C) Office of Pesticide Programs (7508C)
1200 Pennsylvania Ave., NW Room 266A, Crystal Mall 2
Washington, DC 20460 1801 South Bell Street
Arlington, VA 22202
A. Manufacturing Use Products
1. Additional Generic Data Requirements
The generic data base supporting the reregistration of thiram for the above eligible uses has been
reviewed and determined to be substantially complete. However, the following data requirements listed
in Table 22 are necessary to confirm the reregistration eligibility decision documented in this RED.
Table 22. Data Requirements for the Reregistration Eligibility Decision on Thiram
(•uidolino Simlj \juiic
V« (WIS
(.nidi-lim- No.
Old (.uiik'liiK'
No.
UV/Visible Absorption (Prochimie 98.5% T and Gustafson 97.5% T)
830.7050
None
Hydrolysis of Parent and Degradates as a Function of pH at 25" C
835.2120
161-1
Anaerobic Soil Metabolism
835.4200
162-2
Directions for Use
860.1200
171-3
Residue Analytical Method - Plants (propose new method)
860.1340
171-4C
Soil Column Leaching
835.1240
163-1
Directions for Use
860.1200
171-3
Avian Reproduction - Quail
850.2300
71-4A
Nature of the Residue - Plants
860.1300
171-4A
Nature of the Residue - Livestock
860.1300
171-4B
Multiresidue Method
860.1360
171-4M
Storage Stability Data (Plant and Animal Commodities)
860.1380
171-4E
Fish Early-Life Stage Toxicity Test (Plant Commodities - Animal is reserved)
850.1400
72-4C
Life Cycle Fish
850.1500
72-5
Mysid (Shrimp) Chronic Toxicity Test (Prochimie 98.5% T)
850.1350
72-4B
Developmental Neurotoxicity Study (Prochimie 98.5% T)
870.6300
83-6
Product Identity and Disclosure of Ingredients (Composition) (Prochimie 98.5%T)
830.1550
61-1
48
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(•uidolino Simlj \juiic
V« (WIS
(.nidi-lim- No.
Old (.uiik'liiK'
No.
Starting Materials & Manufacturing Process (Description of Materials Used to Proc
the Product (Prochimie 98.5% T)
Iuce830.1600
61-2A
Description of Production Process (Prochimie 98.5% T)
830.1620
61-2B
Discussion of Formation of Impurities (Prochimie 98.5% T)
830.1670
61-2B
Preliminary Analysis (Prochimie 98.5% T)
830.1700
62-1
Certified Limits (Prochimie 98.5% T)
830.1750
62-2
Enforcement Analytical Method (Prochimie 98.5% T)
830.1800
62-3
Color (Prochimie 98.5% T)
830.6302
63-2
Physical State (Prochimie 98.5% T)
830.6303
63-3
Odor (Prochimie 98.5% T)
830.6304
63-4
Stability to Normal and Elevated Temperatures, Metals, and Metal Ions
830.6313
63-13
Oxidation/Reduction: Chemical Incompatibility (Prochimie 98.5% T and Gustafson
97.5% T)
830.6314
63-14
Flammability (Prochimie 98.5% T)
830.6315
63-15
Explodability (Prochimie 98.5% T)
830.6316
63-16
Storage Stability (Prochimie 98.5% T and Gustafson 97.5% T)
830.6317
63-17
Miscibility (Prochimie 98.5% T)
830.6319
63-19
Corrosion Characteristics (Prochimie 98.5% T and Gustafson 91.5% T)
830.6320
63-20
pH of Water Solutions or Suspensions (Prochimie 98.5% T)
830.7000
63-12
Viscosity (Prochimie 98.5% T)
830.7100
63-18
Melting Point/Melting Range (Prochimie 98.5% T)
830.7200
63-5
Boiling Point/Boiling Range (Prochimie 98.5% T)
830.7220
63-6
Density/Relative Density/Bulk Density (Prochimie 98.5% T)
830.7300
63-7
Dissociation Constants in Water (Prochimie 98.5% T)
830.7370
63-10
Partition Coefficient (n-octanol/water), Generator Column Method (Prochimie 98.5%
T)
830.7550
63-11
Water Solubility: Column Elution Method or Shake Flask Method (Prochimie 98.5%
T)
830.7840
63-8
Vapor Pressure (Prochimie 98.5% T)
830.7950
63-9
Magnitude of Residues in Meat/Milk/Poultry/Eggs (milk, fat, meat, and meat
byproducts of cattle, goats, horses and sheep)
860.1480
171-4J
Crop Field Trials (Pome fruits group - apple; Stone fruits group - peach)
860.1500
171-4K
Dermal (Passive Dosimetry) Exposure
875.2400
133-3
Inhalation (Passive Dosimetry) Exposure
875.2500
133-4
2. Labeling for Technical and Manufacturing-Use Products
To ensure compliance with FIFRA, technical and manufacturing use product (MP) labeling
should be revised to comply with all current EPA regulations, PR Notices and applicable policies. The
Technical and MP labeling should bear the labeling contained in Table 23, Label Changes Summary
Table.
49
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B. End-Use Products
1. Additional Product-Specific Data Requirements
Section 4(g)(2)(B) of FIFRA calls for the Agency to obtain any needed product-specific data
regarding the pesticide after a determination of eligibility has been made. The Registrant must review
previous data submissions to ensure that they meet current EPA acceptance criteria and if not, commit
to conduct new studies. If a registrant believes that previously submitted data meet current testing
standards, then the study MRID numbers should be cited according to the instructions in the
Requirement Status and Registrants Response Form provided for each product.
A product-specific data call-in, outlining specific data requirements, accompanies this RED.
2. Labeling for End-Use Products
Labeling changes are necessary to implement measures outlined in Section IV above. Specific
language to incorporate these changes is specified in Table 23.
Registrants may generally distribute and sell products bearing old labels/labeling for 26 months
from the date of the issuance of this Reregistration Eligibility Decision document. Persons other than
the registrant may generally distribute or sell such products for 52 months from the approval of labels
reflecting the mitigation described in this RED. However, existing stocks time frames will be
established case-by-case, depending on the number of products involved, the number of label changes,
and other factors. Refer to "Existing Stocks of Pesticide Products; Statement of Policy "Federal
Register, Volume 56, No. 123, June 26, 1991.
a. Label Changes Summary Table
In order to be eligible for reregistration, amend all product labels to incorporate the risk
mitigation measures outlined in Section IV. The following table describes how language on the labels
should be amended.
50
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Table 23. Thiram Labe
Changes Summary Table
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Manufacturing Use Products
For All Manufacturing Use
Products
"Only for formulation into a fungicide for the following use(s) [fill blank only with those uses that are bein
supported by MP registrant]:"
Labels must be changed by December 31, 2004 to remove foliar treatments to apple, on-farm seed treatmer
to peanuts, and any directions for use on turfgrass, except golf course tees and greens."
No products can be labeled for homeowner/residential use. All labels must contain the statement:
"For sale to and use by professional applicators only. Not for sale to or use by homeowners/consumers."
"All wettable powder formulations except those used exclusively for seed or seed piece treatments must b
packaged in water-soluble packets."
gDirections for Use
ts
e
One of these statements
may be added to allow
reformulation of the
product for specific use or
all additional uses
supported by a formulator
or user group
"This product may be used to formulate products for specific use(s) not listed on the MP label if the
formulator, user group, or grower has complied with U.S. EPA submission requirements regarding
support of such use(s)."
"This product may be used to formulate products for any additional use(s) not listed on the MP label
if the formulator, user group, or grower has complied with U.S. EPA submission requirements
regarding support of such use(s)."
Directions for Use
Environmental Hazards
Statements required by
the RED and Agency
label policies
"This chemical is toxic to fish, aquatic invertebrates, oysters and shrimp. Do not discharge effluent
containing this product into lakes, streams, ponds, estuaries, oceans or other waters unless in accordance
the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting
authority has been notified in writing prior to discharge. Do not discharge effluent containing this produc
sewer systems without previously notifying the local sewage treatment plant authority. For guidance con
your state Water Board or Regional Office of the EPA."
Precautionary
wSthtements
tto
tact
Kiul l so Products Infolded for Occupational I se (WPS and Non-WPS)
51
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Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Front Panel Statement for
all formulations
"For sale to and use by professional applicators only. Not for sale to or use by homeowners/consumers."
Insert in a prominent
position associated with
the Brand name on the
front panel of the
pesticide label
Handler PPE
requirements established b}
the RED1 for wettable
powders formulated in
water-soluble packages
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts correct chemical resistan
material). If you want more options, follow the instructions for category [insert A, B, C, D, E, F, G, or H] 01
an EPA chemical-resistance category selection chart."
"All mixers, loaders, applicators, flaggers, and other handlers must wear:
- long-sleeved shirt and long pants,
- shoes plus socks,
- chemical resistant gloves except when flagging to support aerial applications, applying with aircraft, or
applying while driving motorized ground equipment, and
- chemical resistant apron when mixing, loading, participating in dip treatments*, cleaning up spills, cleani
equipment, or otherwise exposed to the concentrate.
See engineering controls for additional requirements."
* Note: if the directions for use do not contain a dip scenario, the phrase "participating in dip treatments"
should be dropped from the chemical-resistant apron statement.
Precautionary
Statements: Hazards to
Humans and Domestic
i Animals
ig
52
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Handler PPE
requirements established b}
the RED1 for liquid
concentrate, dry flowable,
and water dispersible
granules- formulations
(Except those
formulations labeled solely
for seed, bulb, and/or seed
piece treatments)
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts correct chemical resistan
material). If you want more options, follow the instructions for category [insert
A,B,C,D,E,F,G, or H] on an EPA chemical-resistance category selection chart."
"All mixers, loaders, applicators, people participating in dip treatments, and other handlers must wear:
- long-sleeved shirt and long pants,
- shoes plus socks,
- chemical resistant gloves, except when flagging to support aerial applications, applying with aircraft, or
applying while driving motorized ground equipment,
- chemical resistant apron when mixing, loading, participating in dip treatments*, cleaning up spills, cleani
equipment, or otherwise exposed to the concentrate."
See engineering controls for additional requirements and options."
* Note: if the directions for use do not contain a dip scenario, the phrase "participating in dip treatments"
should be dropped from the chemical-resistant apron statement.
Precautionary
Statements: Hazards to
Humans and Domestic
Animals
ig
Handler PPE
requirements established b}
the RED1 for granular
formulations
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts correct chemical resistan
material). If you want more options, follow the instructions for category [insert
A,B,C,D,E,F,G, or H] on an EPA chemical-resistance category selection chart."
"All loaders, applicators, and other handlers must wear:
- long-sleeved shirt and long pants, and
- shoes plus socks."
Precautionary
Statements: Hazards to
Humans and Domestic
Animals
53
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Handler PPE
requirements established b}
the RED1 for dust
formulations labeled
exclusively for seed and/or
seed piece treatments
NOTE: if wettable powder
formulations are applied
dry to seed or seed pieces,
use this PPE statement
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts chemical resistant
materials). If you want more options, follow the instructions for category [insert A,B,C,D,E,F,G, or
H] on an EPA chemical-resistance category selection chart."
"All loaders, applicators and other handlers must wear:
- long-sleeved shirt and long pants,
- shoes plus socks,
- chemical resistant gloves except when sewing bags of treated seed,* and
- chemical resistant apron when cleaning up spills, or cleaning equipment."
*Note: if the product is labeled for solely for seed piece treatment, then the "except when sewing bags of
treated seed" phrase should be dropped from the chemical-resistant glove statement.
Precautionary
Statements: Hazards to
Humans and Domestic
Animals
Handler PPE
requirements established b}
the RED1 for liquid,
wettable powder*, and dry
flowable formulations
labeled exclusively for seed
and/or seed piece
treatments
NOTE: if wettable powder
formulations are applied
dry to seed or seed pieces,
use the PPE statements
above for dust
formulations
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts chemical resistant
materials). If you want more options, follow the instructions for category [insert A,B,C,D,E,F,G, or
H] on an EPA chemical-resistance category selection chart."
"All mixers, loaders, applicators and other handlers must wear:
- long-sleeved shirt and long pants,
- shoes plus socks,
- chemical resistant gloves except when sewing bags of treated seed, and
- chemical resistant apron when cleaning up spills, or cleaning equipment."
*Note: if the product is labeled for solely for seed piece treatment, then the "except when sewing bags of
treated seed" phrase should be dropped from the chemical-resistant glove statement.
Precautionary
Statements: Hazards to
Humans and Domestic
Animals
54
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Handler PPE
requirements established b}
the RED1 for liquid
concentrate, dry flowable,
or water-dispersible
granule formulations
labeled for both seed or
seed piece treatment and
also for other agricultural
treatment scenarios
"Personal Protective Equipment (PPE)"
"Some materials that are chemical-resistant to this product are (registrant inserts chemical resistant
materials). If you want more options, follow the instructions for category [insert A,B,C,D,E,F,G, or
H] on an EPA chemical-resistance category selection chart."
"All mixers/loaders, applicators and other handlers must wear:
- long-sleeved shirt and long pants,
- shoes plus socks,
- chemical resistant gloves, except when flagging to support aerial applications, applying with aerial
equipment, or sewing bags of treated seed*, and
- chemical resistant apron when mixing, loading, participating in dip treatments**, cleaning up spills,
cleaning equipment, or otherwise exposed to the concentrate."
*Note: if the product is not labeled for seed treatment, then the "except when sewing bags of treated seed
phrase should be dropped from the chemical-resistant glove statement.
** Note: if the directions for use do not contain a dip scenario, the phrase "participating in dip treatments
should be dropped from the chemical-resistant apron statement.
Precautionary
Statements: Hazards to
Humans and Domestic
Animals
Handler PPE
requirements established b}
the RED1 for any
formulations labeled for
seed treatment
"NOTE: Persons involved in bagging treated seed, sewing or moving bags of treated seed, or cleaning up
bagging areas or seed treatment equipment are pesticide handlers and must wear the PPE required on this
label for pesticide handlers."
Precautionary
Statements: Hazards to
Humans and Domestic
Animals Immediately
Following the PPE
Requirements
Handler PPE
requirements established b}
the RED1 for any
formulations labeled for
seed piece treatment
"NOTE: Persons involved in handling, cutting, or sorting treated seed pieces are pesticide handlers and n
wear the PPE required on this label for pesticide handlers."
uBlrecautionary
Statements: Hazards to
Humans and Domestic
Animals Immediately
Following the PPE
Requirements
55
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
User Safety Requirements
"Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for
washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry."
Precautionary
Statements: Hazards to
Humans and Domestic
Animals after PPE
requirements
Engineering controls for
formulations with
directions for use that
permit aerial applications
Enclosed Cockpits
"Engineering Controls:
Pilots must use an enclosed cockpit that meets the requirements listed in the WPS for agricultural pesticid
[40 CFR 170.240(d)(6)]."
Precautionary
Statements: Hazards to
Humans and Domestic
Animals immediately
following the PPE and
User Safety
Requirements
Engineering controls for
wettable powder
formulations packaged in
water-soluble packages
"Engineering Controls"
"Water-soluble packets when used correctly qualify as a closed loading system under the WPS. Mixers a
loaders using water-soluble packets (1) must wear the PPE specified for mixers and loaders, (2) must be
provided, have immediately available, and wear in an emergency, such as a broken package, spill, or
equipment breakdown, chemical-resistant footwear, and a NIOSH-approved dust/mist filtering respirator v
MSHA/NIOSH approval number prefix TC-21C or a NIOSH-approved respirator with any N2, R, P, or HE
filter."
Precautionary
Statements: Hazards to
ndHumans and Domestic
Animals immediately
following the PPE and
ittJser Safety
Requirements
Restricted-Entry Interval
For WPS products as
required by Supplement
Three of PR Notice 93-7
"Do not enter or allow worker entry into treated areas during the restricted
entry interval (REI) of 24 hours."
Directions for Use,
Agricultural Use
Requirements Box
WPS REI Exception
Statement for Products
with Directions for Use as
Seed, Seed Piece, and/or
Bulb Treatments
Exception: Once treated [seeds, seed pieces, bulbs] are planted in soil or other planting media, the Workei
Protection Standard allows workers to enter the treated area without restriction, if there will be no contact
with the treated [seeds, seed pieces, or bulbs]."
Directions for Use,
Agricultural Use
Requirements Box
Immediately Following
the REI Statement
56
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Early Entry Protective
Equipment for products
with WPS uses
Early Entry PPE
"PPE required for early entry to treated areas that is permitted under the Worder Protection Standard and
involves contact with anything that has been treated, such as plants, soil, or water, is:
- coveralls,
- shoes plus socks,
- chemical-resistant gloves made of any waterproof material, and
- protective eyewear."
Directions for Use,
hAgricultural Use
Requirements Box
User Safety
Recommendations
"User Safety Recommendations"
"Users should wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet."
"Users should remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly and
put on clean clothing."
"Users should remove PPE immediately after handling this product. Wash the outside of gloves
before removing. As soon as possible, wash thoroughly and change into clean clothing."
Precautionary
Statements under:
Hazards to Humans
and Domestic Animals
immediately following
Engineering Controls
(Must be placed in a
box)
Environmental Hazards for
products used with outdooi
uses only
"Environmental Hazards"
"This chemical is toxic to fish, aquatic invertebrates, oysters, and shrimp. Do not apply directly to water,
to areas where surface water is present or to intertidal areas below the mean high water mark. Drift and
runoff from treated areas may be hazardous to aquatic organisms in neighboring areas. Do not contamina
water when cleaning equipment or disposing of equipment washwaters or rinsate."
Precautionary
Statements under
^Environmental Hazards
e
Additional Environmental
Hazards
for all products labeled for
seed, seed piece, and/or
bulb treatments
Note: if the label doesn't
contain directions for use
for seeds or seed pieces or
bulb treatments, drop that
use from the statement.
"Environmental Hazards"
"Treated [seeds, seed pieces, bulbs] are hazardous to fish, birds and mammals. Do not plant treated seed:
seed pieces by broadcasting to the soil surface. Ensure that all [seeds, seed pieces, bulbs] are thoroughly
covered with soil, especially in turn areas. If [seeds, seed pieces, bulb] are not thoroughly incorporated I
the planter during planting, additional incorporation may be required to thoroughly cover exposed seeds,
pieces, bulbs]."
Precautionary
Statements under
; (gnvironmental Hazards
r
y
seed
57
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Endangered Species
Statement
Endangered Species
"This bag contains seed treated with thiram. This product may have effects on federally listed threatened
endangered species or their critical habitat in some counties. It is a violation of federal law to kill, harm or
harass listed animal species without authorization. To limit the potential for such impacts when using this
product, consult and follow the instructions provided in the EPA Endangered Species Bulletin for the Coi
or Parish in which you are applying the seed. To determine whether your County or Parish has a Bulletin
consult httD://www.eDa.eov/esDD before each season's use of this product."
Precautionary
Statements immediately
ofollowing the User Safety
Recommendations
nty
Application Restrictions foi
formulations applied as a
spray
"Do not apply this product using a high pressure handwand or a rights-of-way sprayer."
Directions for Use
Application Restrictions foi
granular products
"Application by hand, spoon, or cup or with aerial or belly grinder equipment is prohibited. Apply this
product with a motorized ground spreader, a push-type spreader, or a granular backpack spreader."
Directions for Use
Application Restrictions
for all products except
products labeled
exclusively for seed or seed
piece treatment.
"Do not apply this product in a way that will contact workers or other persons, either directly or
through drift. Only protected handlers may be in the area during application."
Directions for Use
Application Restrictions
for products labeled
exclusively for seed or seed
piece treatment.
"Do not apply this product in a way that will contact workers or other persons. Only protected handlers n
be in the area during application."
iap)irections for Use
58
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Other Use/Application
Restrictions
Cotton Seed
When cotton seed is treated in products containing thiram as the single active ingredient:
"The maximum application rate for cotton seed is 1.6 oz ai/cwt (1,000 ppm)."
When cotton seed is treated with thiram in products containing multiple active ingredients:
"The maximum application rate for cotton seed is 1.0 oz ai/cwt (625 ppm)."
"Plant treated cotton seed a minimum of 1 inch deep."
Barlev Seed
"Plant barley seed a minimum of 1 inch deep."
Oat Seed
"Plant oat seed a minimum of 1 inch deep."
Suear Beet Seed
"Plant sugar beet seed a minimum of 1 inch deep."
Wheat Seed
"Plant wheat seed a minimum of 1 inch deep."
Onion Seed
"When 1.5 lbs ai/cwt is used, the onion seed must undergo pelletized treatment."
Directions for Use
under General
Precautions and
Restrictions and/or
Applications
Instructions
59
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
If strawberries are
reinstated on the label, then
the following language
must be on the label under
Other Use/Application
Restrictions
Strawberries
For all products applied to strawberries:
"Leave 25 foot untreated buffer between treatment area and native plant communities and water bodies."
When strawberries are treated in products containing thiram as the single active ingredient:
"The maximum application rate for strawberries is 2.6 lbs ai/acre .
Limit to 5 applications per year areas west of the Mississippi River. Limit to 12 applications per year areas
east of the Mississippi River."
When strawberries are treated with thiram in products containing multiple active ingredients:
"The maximum application rate for strawberries is 1.3 lbs ai/acre.
Limited to 5 applications per year areas west of the Mississippi River. Limit to 12 applications per year are;
east of the Mississippi River."
Directions for Use
under General
Precautions and
Restrictions and/or
Applications
Instructions
is
Other Use/Application
Restrictions for products
used as a mammal
repellant
"The maximum application rate for products applied as a mammal (deer) repellant is one quart of product ir
3-7 gallons of water applied in an area of 1000 square feet."
Directions for Use under
specific directions for
animal repellant
Other Use/Application
Restrictions for all uses
except seed treatment
Golf Course Tees and Greens
"The maximum winter application rate for turf is a single application of 16.3 lbs ai/ acre or 0.374 lbs. ai/1000
sq ft. The maximum summer application rate for turf is 3 applications of 10.2 lbs ai/ acre or 0.234 lbs ai/100(
sq ft. The maximum annual application rate is 47 lbs ai/acre or 1.08 lbs ai/1000 sq ft."
Directions for Use
under General
Precautions and
Restrictions and/or
Applications
Instructions
60
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Entry Restrictions for
products containing
directions for use on golf
course tees and greens
"Do not enter or allow others to enter until sprays have dried."
If no WPS uses on the
label, place the
statements in the
Directions for Use Under
General Precautions and
Restrictions
If WPS uses are also on
the labeling, place these
statements in a
Nonagricultural Use
Requirements box as
specified in PR Notice
93-7 and 93-11
Environmental Hazards
Statements Required by the
RED and Agency Label
Policies for seeds, seed
pieces, or bulbs that are
treated with this product
that is then packed or
bagged for future use
"[Seeds, Bulbs, Seed Pieces] that are treated with this product and are then packaged or bagged for futur
must contain the following labeling on the outside of the [seed, bulb, seed piece] package or bag:"
Endangered Species
"This bag contains seed treated with thiram. This product may have effects on federally listed threatened
endangered species or their critical habitat in some counties. It is a violation of federal law to kill, harm or
harass listed animal species without authorization. To limit the potential for such impacts when using this
product, consult and follow the instructions provided in the EPA Endangered Species Bulletin for the Coi
or Parish in which you are applying the seed. To determine whether your County or Parish has a Bulletin
consult httD://www.eDa.eov/esDD before each season's use of this product."
; E&eections for Use under
the specific instructions
for treating seeds, bulbs,
and seed pieces.
or
nty
61
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Application Restrictions foi
seeds, seed pieces, and
bulbs that are treated with
this product and then
packaged or bagged for
future agriculture or
research use
"[Seed, [Bulbs, Seed Pieces] that are treated with this product and are then packaged or bagged for future
by growers or researchers must contain the following labeling on the outside of the [seed, bulb, seed piec
package or bag:"
>"This bag contains [seeds, bulbs, seed pieces] treated with thiram. When opening this bag or
loading/pouring the treated [seeds, bulbs, seed pieces], wear long-sleeved shirt, long pants, shoes, socks
chemical resistant gloves."
>"Treated [Seeds, Bulbs, Seed Pieces] - Do Not Use for Food, Feed, or Oil Purposes."
>"After the [seeds, bulbs, seed pieces] have been planted, do not enter or allow worker entry into treated
during the restricted-entry interval (REI) of 24 hours. Exception: Once the [seeds, bulbs, seed pieces] are
planted in soil or other planting media, the Worker Protection Standard allows workers to enter the treated
area without restriction if there will be no worker contact with the [seeds, bulbs, seed pieces]."
uBirections for Use under
j]the specific instructions
for treating seeds, bulbs,
and seed pieces.
and
ireas
Application Restrictions foi
seeds, seed pieces, and
bulbs that are treated with
this product and are then
packaged or bagged for
future homeowner or
residential use
"[Seed, bulbs, seed pieces] that are treated with this product and are then packaged or bagged for future
by homeowners or other residential users must contain the following labeling on the outside of the [seed,
bulb, seed piece] package or bag:"
>"Treated [Seed , Bulbs, Seed Pieces] - Do Not Use for Food, Feed, or Oil Purposes."
uJSirections for Use under
the specific instructions
for treating seeds, bulbs,
and seed pieces.
Environmental Hazards
Statements Required by the
RED and Agency Label
Policies for seeds, bulbs, or
seed pieces that are treated
with this product and are
then packed or bagged for
future use
"[Seeds, Bulbs, Seed Pieces] that are treated with this product and are then packaged or bagged for future
must contain the following labeling on the outside of the [seed, bulb, seed piece] package or bag:"
>"Treated [seeds, bulbs, seed pieces] are hazardous to fish, birds and mammals. Do not plant treated seei
bulbs, seed pieces] by broadcasting to the soil surface. Ensure that all planted seeds [bulbs, seed pieces]
thoroughly covered with soil, especially in turn areas. If [seeds, bulbs, seed pieces] are not thoroughly
incorporated by the planter during planting, additional incorporation may be required to thoroughly cove
exposed [seeds, bulbs, seed pieces]. Do not apply to water, to areas where surface water is present, or to
intertidal areas below the mean high water mark. Do not contaminate water when disposing of equipment
washwater or rinsate or by disposal of wastes."
In addition for cotton, wheat, barley, oats, and sugar beets include the statement:
>"Plant [cotton, wheat, barley, oats, and sugar beet] seed a minimum of 1 inch deep."
iBtrections for Use under
the specific instructions
for treating seeds, bulbs,
Isijnd seed pieces,
are
r
62
-------
Summary of Required Labeling Changes for Thiram
Description
Required Labeling
Placement on Label
Spray Drift language for
products applied outdoors
as a spray
"SPRAY DRIFT MANAGEMENT"
"Avoiding spray drift at the application site is the responsibility of the applicator. The interaction of man;
equipment-and-weather-related factors determine the potential for spray drift. The applicator and the gro\
are responsible for considering all these factors when making decisions."
"Apply only as a medium or coarser spray (ASAE standard 572) or a volume mean diameter of 300 micron:
or greater for spinning atomizer nozzles."
"Apply only when the wind speed is 2-10 mph at the application site."
Additional requirements for aerial applications:
"The boom length must not exceed 75% of the wingspan or 90% or the rotor blade diameter."
"Release spray at the lowest height consistent with efficacy and flight safety. Do not release spray at a hi
greater than 15 feet above the crop canopy."
"When applications are made with a crosswind, the swath will be displaced downwind. The applicator mi
compensate for this displacement at the downwind edge of the application area by adjusting the path of tl
aircraft upwind."
"Do not make applications into temperature inversions."
Additional requirements for ground boom application:
"Do not apply with a nozzle height greater than 4 feet above the crop canopy."
Directions for Use
T
iq r
:ight
ist
Le
1 PPE that is established on the basis of Acute Toxicity of the end-use product must be compared to the active ingredient PPE in this document. The more protective PPE
must be placed in the product labeling. For guidance on which PPE is considered more protective, see PR Notice 93-7.
2 The registrant must drop the N type filter from the respirator statement if the pesticide product contains or is used with oil.
63
-------
64
-------
APPENDICES
65
-------
66
-------
Appendix A: Til I RAM USE PATTERNS ELIGIBLE FOR REREGISTRATION
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.]
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Foliar Uses
Apple
Foliar or delayed dormant
(including prebloom
through first cover spray
and preharvest)
Ground or aerial
75% DF
[45728-21]
4.5 lb/A
(concentrate)
1.125 lb/100 gal
(dilute)
Not specified
(NS)
22.5 lb/A
14
Use limited to eastern U.S. (East of the
Rockies); use prohibited in CA.
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 400 gal/A), or aerial
applications may be made in a minimum of
10 gal/A. The grazing or feeding of cover
crops from treated orchards is prohibited.
21 lb/A
7
Use limited to western U.S. (West of the
Rockies); use prohibited in CA.
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 400 gal/A), or aerial
applications may be made in a minimum of
10 gal/A. The grazing or feeding of cover
crops from treated orchards is prohibited.
Foliar or delayed dormant
(including prebloom,
bloom, calyx, petal fall,
and cover periods)
Ground or aerial
65% WP
[45728-24]
5.2 lb/A
(concentrate)
or
1.3 lb/100 gal
(dilute)
NS
NS
NS
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 400 gal/A), or aerial
applications may be made in a minimum of
10 gal/A. The grazing or feeding of cover
crops from treated orchards is prohibited.
67
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Peach
Foliar or delayed dormant
(from pink through early
cover spray and
preharvest)
Ground or aerial
75% DF
[45728-21]
2.625 lb/A
(concentrate)
0.9 lb/100 gal
(dilute)
NS
13.125 lb/A
7
Use prohibited in CA. Concentrate ground
applications may be made in a minimum of
20 gal/A, dilute applications may be made ir
100 gals (based on a finished spray of 300
gal/A), or aerial applications may be made ii
a minimum of 10 gal/A. The grazing or
feeding of cover crops from treated orchard:
is prohibited.
Dormant (postharvest in
late fall after leaf drop
and/or late winter prior to
bud swell) and foliar (at
bloom and petal fall)
Ground or aerial
3.825 lb/A
(concentrate)
1.275 lb/100 gal
(dilute)
NS
NS
NS
Dormant, delayed
dormant, or foliar
Ground or aerial
65% WP
[45728-24]
4.5 lb/A
(concentrate)
or
1.5 lb/100 gal
(dilute)
NS
NS
7
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 300 gal/A), or aerial
applications may be made in a minimum of
10 gal/A. The grazing or feeding of cover
crops from treated orchards is prohibited.
68
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Strawberry
Foliar (beginning at early
blossom stage through
preharvest)
Ground or aerial
75% DF
[45728-21]
3.3 lb/A
(concentrate)
3.3 lb/100 gal
(dilute)
5
NS
5
Use limited to eastern U.S. (East of the
Rockies); use prohibited in FL.
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 100 gal/A), or aerial
applications may be made in a minimum of
10 gal/A with a 10-day retreatment interval.
3
Use limited to western U.S. (West of the
Rockies); use prohibited in CA.
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 100 gal/A), or aerial
applications may be made in a minimum of
10 gal/A with a 10-day retreatment interval.
69
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Strawberry (continued)
3.315 lb/A
(concentrate)
or
5
NS
5
Use limited to eastern U.S. (East of the
Rockies); use prohibited in FL.
Concentrate ground applications may be
made in a minimum of 20 gal/A, dilute
applications may be made in 100 gals (basei
on a finished spray of 100 gal/A), or aerial
applications may be made in a minimum of
10 gal/A with a 10-day retreatment interval.
Foliar (when new growth
begins in the spring and
before fruit starts to form)
Ground or aerial
65% WP
[45728-24]
1.69 lb/100 gal
(dilute)
3
Use limited to FL. Concentrate ground
applications may be made in a minimum of
20 gal/A, dilute applications may be made ir
100 gals (based on a finished spray of 100
gal/A), or aerial applications may be made ii
a minimum of 10 gal/A with a 10-day
retreatment interval.
2.21 lb/A
(concentrate)
or
1.105 lb/100 gal
(dilute)
5
NS
1
Use limited to FL. Concentrate ground
applications may be made in a minimum of
20 gal/A, dilute applications may be made ir
100 gals (based on a finished spray of 100
gal/A), or aerial applications may be made ii
a minimum of 10 gal/A with a 10-day
retreatment interval.
70
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Strawberry (continued)
Foliar (when new growth
begins in the spring and
before fruit starts to form)
Ground or aerial
65% WP
[45728-24]
3.315 lb/A
(concentrate)
or
1.69 lb/100 gal
(dilute)
5
NS
3
Use limited to western U.S. (West of the
Rockies); use prohibited in Santa Maria anc
Fallbrook counties of CA. Concentrate
ground applications may be made in a
minimum of 20 gal/A, dilute applications
may be made in 100 gals (based on a
finished spray of 100 gal/A), or aerial
applications may be made in a minimum of
10 gal/A with a 10-day retreatment interval.
2.21 lb/A
(concentrate)
or
1.105 lb/100 gal
(dilute)
5
NS
5
Use limited to Santa Maria and Fallbrook
counties of CA. Concentrate ground
applications may be made in a minimum of
20 gal/A, dilute applications may be made ir
100 gals (based on a finished spray of 100
gal/A), or aerial applications may be made ii
a minimum of 10 gal/A with a 10-day
retreatment interval.
71
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Seed Treatments2
Alfalfa and other small seed le
gumes
Seed treatment
Slurry
30% F1C
[7501-17]
44.1 fl.oz
product/cwt
Not applicable
(NA)
NA
NA
2.4 lb/gal SC
[7501-125]
1.8 oz/bushel
NA
NA
NA
Barley
Seed treatment
Dry or slurry
75% DF
[45728-21]
2 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.05 oz/cwt
NA
NA
NA
Seed treatment
Dry
20% D
[7501-44]
0.8 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.2 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
12.8 fl.oz
product/cwt
NA
NA
NA
72
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Barley (continued)
Seed treatment
Slurry (undiluted)
1.17 lb/gal RTU
[7501-141]
[MT90006]
0.88 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
13.2% F1C
[7501-133]
5.0 fl.oz product/cwt
NA
NA
NA
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
1.33 lb/gal RTU
[7501-80]
1.5 oz/cwt
NA
NA
NA
Application rates less than 1 oz ai must be
diluted with water. The grazing of green
forage within 40 days of seeding is
prohibited.
Seed treatment
Slurry (diluted)
1.84 lb/gal F1C
[7501-151]
1.06 oz/cwt
NA
NA
NA
The grazing of barley within 31 days after
planting is prohibited.
Bean (dry and succulent)
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
1.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.0 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
11.0 fl.oz
product/cwt
NA
NA
NA
73
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Bean (dry and succulent)(continued)
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
4.0 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on vine;
grown from treated seed is prohibited.
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of bean forage to
livestock within 60 days after treated seed is
planted is prohibited.
Bean, Lima
Seed treatment
Dry or slurry
50% WP/D
[7501-105]
1.5 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.4 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.5 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
16.4 fl.oz
product/cwt
NA
NA
NA
Bean, snap
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
1.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.0 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
11.0 fl.oz
product/cwt
NA
NA
NA
74
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Beet, garden
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Beet, sugar
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Broccoli
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
75
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Brussels sprouts
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Cabbage
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Canola
Seed treatment
Dry or slurry
75% DF
[45728-21]
3.2 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
3.2 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
3.2 oz/cwt
NA
NA
NA
6.57% F1C
[ID930004]
34.6 fl.oz
product/cwt
NA
NA
NA
Use limited to ID for canola seed/rapeseed
destined for export to Canada.
76
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Carrot
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Castor bean
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.3 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.25 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
2.25 oz/cwt
NA
NA
NA
Cauliflower
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
77
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Celery
Seed treatment
Slurry
4 lb/gal F1C
[CA970027]
3.36 oz/cwt3
NA
NA
NA
Use limited to CA for celery seed destined
for export only.
Chicory
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.6 oz/cwt
NA
NA
NA
Use prohibited in CA.
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
2.25 oz/cwt
NA
NA
NA
Clover and other small seeded legumes
Seed treatment
Slurry
30% F1C
[7501-17]
44.1 fl.oz
product/cwt
NA
NA
NA
2.4 lb/gal SC
[7501-125]
1.8 oz/bushel
NA
NA
NA
Collards
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Coriander
Seed treatment
Slurry
4 lb/gal F1C
[WA970032]
2.5 oz/cwt
NA
NA
NA
Use limited to WA for coriander seed
destined for export to Mexico.
78
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Corn, field
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.5 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
0.75 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
0.75 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
15.2 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
5.0 fl.oz product/cwt
11.5 fl.oz
product/cwt for
control of corn head
smut
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting
grain crops is prohibited.
79
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Corn, sweet
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.5 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.5 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
2.5 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
16.2 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
5.0 fl.oz product/cwt
11.5 fl.oz
product/cwt for
control of corn head
smut
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting
grain crops is prohibited.
80
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Cottonseed (acid and machined delinted, fuzzy, and reginned)
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.3 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
2.25 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.2 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
2.25 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
22.3 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
1.33 lb/gal RTU
[7501-80]
2.0 oz/cwt
NA
NA
NA
Application rates less than 1 oz ai must be
diluted with water. The grazing of green
forage within 40 days of seeding is
prohibited.
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
Cowpea
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
1.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
11.0 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/cwt
NA
NA
NA
81
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Cucurbits (including cantaloupe, cucumber, pumpkin, squash, and watermelon)
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.3 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
2.25 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.28 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
2.25 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
14.2 fl.oz
product/cwt
NA
NA
NA
Eggplant
Seed treatment
Dry or slurry
75% DF
[45728-21]
3.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
3.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
19.8 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
3.25 oz/cwt
NA
NA
NA
82
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Endive
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Flax
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.6 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.65 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.4 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.5 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
15.5 fl.oz
product/cwt
NA
NA
NA
83
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Grasses
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
10% RTU
[OR950034]
14.0 fl.oz
product/cwt
NA
NA
NA
Use limited to OR for grass seed destined f( i
export only.
Kale
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
84
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Kohlrabi
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Legume (small-seeded)
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Lentils
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
Seed treatment
Slurry
30% F1C
[7501-17]
16.4 fl.oz
product/cwt
NA
NA
NA
85
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Lettuce
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Millet
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
13.5 fl.oz
product/cwt
NA
NA
NA
Mustard
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
86
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Oats
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.7 oz/cwt
NA
NA
NA
Use prohibited in CA.
Seed treatment
Dry
20% D
[7501-44]
0.8 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
Seed treatment
Slurry (diluted)
1.84 lb/gal F1C
[7501-151]
1.06 oz/cwt
NA
NA
NA
The grazing of oats within 30 days after
planting is prohibited.
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
5.0 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting
grain crops is prohibited.
1.17 lb/gal RTU
[7501-141]
[MT90006]
0.73 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
1.33 lb/gal RTU
[7501-80]
1.5 oz/cwt
NA
NA
NA
Application rates less than 1 oz ai must be
diluted with water. The grazing of green
forage within 40 days of seeding is
prohibited.
Okra
Seed treatment
Dry or slurry
75% DF
[45728-21]
3.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
3.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
3.0 oz/cwt
NA
NA
NA
87
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Onion
Seed treatment
50% D
[CA850026]
[NJ940001]
TWA8400701
1.25 lb/cwt
NA
NA
NA
Use limited to CA, NJ, and WA for onion
seed destined for export to Canada.
Dry
50% WP/D
[AZ920005]
[CA890029]
[MI880007]4
3.0 oz/cwt
NA
NA
NA
Use limited to AZ and CA.
Seed treatment
75% DF
[45728-21]
3.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
Dry or slurry
50% WP/D
[7501-105]
3.0 oz/cwt
NA
NA
NA
Seed treatment
30% F1C
[7501-17]
19.8 fl.oz
product/cwt
NA
NA
NA
Slurry
4 lb/gal F1C
[7501-14]
3.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
Peanut (shelled and unshelled)
Seed treatment
75% DF
[45728-21]
2.3 oz/cwt
NA
NA
NA
Use prohibited in CA.
Dry or slurry
50% WP/D
[7501-105]
2.25 oz/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
4 lb/gal F1C
[7501-14]
1.5 oz/cwt
NA
NA
NA
88
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Pea
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.5 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.4 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.5 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
16.4fl.oz
product/cwt
NA
NA
NA
Pepper
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
89
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Radish
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Rice
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.2 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.15 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
0.75 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
0.75 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
35.1 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
2.0 oz/cwt
NA
NA
NA
Use limited to CA.
Seed treatment
Slurry (undiluted)
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
90
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Rye
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.9 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.85 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
0.98 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
10.8 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
1.33 lb/gal RTU
[7501-80]
1.5 oz/cwt
NA
NA
NA
Application rates less than 1 oz ai must be
diluted with water. The grazing of green
forage within 40 days of seeding is
prohibited.
Safflower
Seed treatment
Dry or slurry
75% DF
[45728-21]
2.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
2.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
10.8 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
17% F1C
[MT850002]
4.0 fl.oz product/cwt
NA
NA
NA
Use limited to MT.
91
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Sesame
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.5 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.5 oz/cwt
NA
NA
NA
Seed treatment
Slurry
4 lb/gal F1C
[7501-14]
1.5 oz/cwt
NA
NA
NA
Sorghum
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.4 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
1.35 oz/cwt
NA
NA
NA
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
1.6 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
13.5 fl.oz
product/cwt
NA
NA
NA
92
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Soybean
Seed treatment
Dry
26.6% D
[7501-117]
1.0 oz/bushel
NA
NA
NA
Seed treatment
75% DF
[45728-211
1.7 oz/cwt
NA
NA
NA
Use prohibited in CA.
Dry or slurry
50% WP/D
[7501-105]
1.65 oz/cwt
NA
NA
NA
2.9 lb/gal SC
[7501-64]
0.72 oz/cwt
NA
NA
NA
Seed treatment
2.4 lb/gal SC
[7501-125]
0.6 oz/bushel
NA
NA
NA
Slurry
4 lb/gal F1C
[7501-14]
1.0 oz/cwt
NA
NA
NA
30% F1C
[7501-17]
ll.0fl.oz
product/cwt
NA
NA
NA
13.2% F1C
[7501-133]
4.0 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on vine;
6.4% RTU
[7501-95]
10.0fl.oz
product/cwt
NA
NA
NA
grown from treated seed is prohibited.
Seed treatment
Slurry (undiluted)
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on
soybean forage or soybean hay from treate>
areas is prohibited.
1.25 lb/gal RTU
[7501-158]
0.625 oz/bushel
NA
NA
NA
1.2 lb/gal RTU
[7501-121]
[7501-123]
0.6 oz/bushel
NA
NA
NA
93
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Soybean (continued)
Seed treatment
Slurry (undiluted or
diluted)
1.1 lb/gal RTU
[7501-135]
0.91 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
soybean forage or soybean hay from treate>
areas is prohibited.
Spinach
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Sunflower
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.1 oz/cwt
NA
NA
NA
Use prohibited in CA.
Seed treatment
Slurry
30% F1C
[7501-17]
11.0 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
94
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Swiss chard
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
Tomato
Seed treatment
Dry or slurry
75% DF
[45728-21]
3.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
3.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
19.8 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
95
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
T riticale
Seed treatment
Dry or slurry
75% DF
[45728-21]
1.7 oz/cwt
NA
NA
NA
Use prohibited in CA.
Seed treatment
Slurry
4 lb/gal F1C
[7501-141
1.0 oz/bushel
NA
NA
NA
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
3.0 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting
grain crops is prohibited.
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
Turnip
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-105]
4.0 oz/cwt
NA
NA
NA
Seed treatment
Slurry
30% F1C
[7501-17]
26.5 fl.oz
product/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
4.0 oz/cwt
NA
NA
NA
96
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Wheat
Seed treatment
Dry or slurry
75% DF
[45728-21]
4.0 oz/cwt
NA
NA
NA
Use prohibited in CA.
50% WP/D
[7501-1051
1.65 oz/cwt
NA
NA
NA
Seed treatment
Dry
20% D
[7501-44]
0.8 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
Seed treatment
Slurry
2.9 lb/gal SC
[7501-64]
0.93 oz/cwt
NA
NA
NA
4 lb/gal F1C
[7501-14]
1.0 oz/bushel
NA
NA
NA
30% F1C
[7501-17]
10.1 fl.oz
product/cwt
NA
NA
NA
Seed treatment
Slurry (undiluted)
13.2% F1C
[7501-133]
5.0 fl.oz product/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting
grain crops is prohibited.
1.17 lb/gal RTU
[7501-141]
[MT90006]
0.73 oz/cwt
NA
NA
NA
The grazing or feeding of livestock on
treated areas for six weeks after planting is
prohibited.
10% RTU
[7501-114]
6.8 fl.oz product/cwt
NA
NA
NA
1.33 lb/gal RTU
[7501-80]
1.5 oz/cwt
NA
NA
NA
Application rates less than 1 oz ai must be
diluted with water. The grazing of green
forage within 40 days of seeding is
prohibited.
97
-------
Site
Application Timing
Application Type
Application Equipment
Formulation
[EPA Reg. No.l
Maximum Single
Application Rate, ai
Maximum
Number of
Applications Per
Season
Maximum
Seasonal Rate, ai
Preharvest
Interval,
Days
Use Directions and Limitations1
Wheat (continued)
Seed treatment
Slurry (undiluted or
diluted)
1.1 lb/gal RTU
[7501-135]
0.91 oz/cwt
NA
NA
NA
Seed treatment
Slurry (diluted)
1.84 lb/gal F1C
[7501-1511
1.06 oz/cwt
NA
NA
NA
The grazing of wheat within 30 days after
planting is prohibited.
1 Only crops with registered thiram uses may be rotated is specified on the product label for the 75% DF (EPA Reg. No. 45728-21) formulation.
2 The Thiram Task Force II has submitted metabolism studies derived from seed treatment of soybean, sugar beets, and wheat. Because these data indicate breakdown of thiram in
soil followed by incorporation into natural components, the Agency has concluded that thiram seed treatment uses are non-food uses and that no tolerances are required for seed
treatment uses of thiram.
3 The parent registration is a 4 lb/gal F1C (42% thiram) formulation, however, the label rate is expressed in ounces of product. The maximum single application rate was calculated
from percent active ingredient.
4 Contents of registration j acket copied for SLN No. MI880007, however, no label was available for review.
98
-------
Appendix B. TABLE OF GENERIC DATA REQUIREMENTS AND STUDIES USED TO MAKE THE REREGISTRATION DECISION
GIITDE TO APPENDIX B
Appendix B contains listing of data requirements which support the reregistration for active ingredients within case #0022 (thiram) covered by this
RED. It contains generic data requirements that apply to thiram in all products, including data requirements for which a "typical formulation" is the test
substance.
The data table is organized in the following formats:
1. Data Requirement (Column 1). The data requirements are listed in the order in which they appear in 40 CFR part 158. The reference numbers
accompanying each test refer to the test protocols set in the Pesticide Assessment Guidance, which are available from the National technical
Information Service, 5285 Port Royal Road, Springfield, VA 22161 (703) 487-4650.
2. Use Pattern (Column 2). This column indicates the use patterns for which the data requirements apply. The following letter designations are
used for the given use patterns.
A.
Terrestrial food
B.
Terrestrial feed
C.
Terrestrial non-food
D.
Aquatic food
E.
Aquatic non-food outdoor
F.
Aquatic non-food industrial
G.
Aquatic non-food residential
H.
Greenhouse food
I.
Greenhouse non-food
J.
Forestry
K.
Residential
L.
Indoor food
M.
Indoor non-food
N.
Indoor medical
O.
Indoor residential
3. Bibliographic Citation (Column 3). If the Agency has acceptable data in its files, this column list the identify number of each study. This
normally is the Master Record
99
-------
Identification (MIRD) number, but may be a "GS" number if no MRID number has been assigned. Refer to the Bibliography appendix for a
complete citation of the study.
100
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
PRODUCT CHEMISTRY
830.1550
61-1
Product Identity and Composition
A,B,C,K
00143624, 00161985, 40224501, 41006301, 41006302, 41006303, 4112401,
44550808, 44550809, 44550810, 44550811, Data Gap
830.1600
61-2a
Start. Mat. & Mfg. Process
A,B,C,K
00148170, 00149379, Data gap
830.1620
61-2b
Description of Production Process
A,B,C,K
00148170, 00149379, Data gap
830.1670
61-2b
Discussion of Impurities
A,B,C,K
00148170, Data gap
830.1700
62-1
Preliminary Analysis
A,B,C,K
00148170, 00149379, Data gap
830.1750
62-2
Certification of limits
A.B.C.K
00148170. Data gaD
830.1800
62-3
Analytical Method
A,B,C,K
00162015, 00161985, Data gap
830.6302
63-2
Color
A,B,C,K
00148170, 00149379, Data gap
830.6303
63-3
Physical State
A,B,C,K
00148170, 00149379, Data gap
830.6304
63-4
Odor
A,B,C,K
00148170, 00149379, 00148415, Data gap
830.6313
63-13
Stability - temp and ions
A,B,C,K
00149379, 44550811, Data gap
830.6314
63-14
Oxidation and Reduction
A,B,C,K
Data gap
830.6315
63-15
Flammability
A,B,C,K
Data gap
830.6316
63-16
Explodability
A,B,C,K
Data gap
830.6317
63.17
Storage stability
A,B,C,K
42910401, Data gap
830.6319
63-19
Miscibility
A,B,C,K
Data gap
830.6320
63-20
Corrosion Characteristics
A,B,C,K
42910201, Data gap
830.7000
63-12
PH
A,B,C,K
00148170, 00149379, Data gap
830.7050
none
UV/Visible absorption
AJ3.C.K
Data gap
830.7100
63-18
Viscosity
A,B,C,K
Data gap
830.7200
63-5
Meltina Doint/meltina ranae
A.B.C.K
00148170. 00149379. 00148415. Data gaD
101
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
830.7220
63-6
Boiling point/range
A,B,C,K
Data gap
830.7300
63-7
Density
A,B,C,K
00148170, 00149379, Data gap
830.7370
63-10
Dissociation Constants in Water
A,B,C,K
00151609, 00152557, Data gap
830.7550
63-11
Partial Coefficient, shake flask method
A,B,C,K
00147102, 00148170, 00149379, 00148415, Data gap
830.7840
830.7860
63-8
Water Solubility
A,B,C,K
00147102, 00148170, 00149379, 00148415, Data gap
830.7950
63-9
Vapor Pressure
A,B,C,K
00148487, 00152557, Data gap
ECOLOGICAL EFFECTS
850.2100
71-1
Avian Acute Toxicology
A,B,C,K
BAOTH103, 00075683
850-2200
71-2
Avian Subacute Dietary
A,B,C,K
00022923
850.2300
71-4a
Avian ReDroduction - auail
A.B.C.K
43612502
850.2300
71-4b
Avian Reproduction - duck
A,B,C,K
43612501, 45441201, Data gap
850.2500
71-5a
Simulated or Actual Field Testing
A,B,C,K
43612505, 43612506
850.1075
72-1
Fish Acute Toxicity
A,B,C,K
00070801, BAOTH102, 00090293, 00034713
850.1010
72-2
Acute Toxicity to Freshwater
Invertebrates
A,B,C,K
00164662
850.1055
72-3
Acute Toxicity to Estuarine/Marine
Organisms (fish, mollusk, shrimp)
A,B,C,K
42514401, 42488301, 42488302
850.1300
72-4a
Fish- Early Life Stage
A,B,C,K
Data Gap
850.1350
72-4b
Life cycle freshwater, aquatic
invertebrate
A,B,C,K
00164662, Data Gap
850.1500
72-5
Life cycle fish
A,B,C,K
42514401, Data Gap
850.4400
122-2
Aauatic Plant Toxicity
A.B.C.K
45444202. 44086101
102
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
OCCUPATIONAL/RESIDUE EXPOSURE
875.2100 and
875.2200
132-laandb
Dissipation of Dislodgeable Foliar and
Soil Residues
A,B,C,K
Data Gap
875.2400
133-3
Dermal Passive Dosimetry Exposure
A,B,C,K
Data Gap
875.2500
133-4
Inhalation Passive Dosimetry Exposure
A,B,C,K
Data Gap
NONE
85-3
Dermal Absorption
A,B,C,K
Data Gap
875.1100
None
Dermal Exposure Study
A,B,C,K
45442701, Data gap
875.1300
None
Inhalation Exposure Study
A,B,C,K
45442701, Data gap
875.1600
236
Application Exposure Monitoring
Data
A,B,C,K
45250701,45250702,45654501,42251901, 42251902, 44904526, 43080*
47031611
875.1100
875.1200
231
233
Estimation of Dermal Exposure
A,B,C,K
45442701,
875.1300
875.1400
234
235
Estimation of Inhalation Exposure
A,B,C,K
45442701
TOXICOLOGY
870.1100
81-1
Acute Oral Toxicity-Rat
A,B,C,K
00163854,00153548, 42095901
850.3020
144-1
Acute Contact Toxicity - Insect
A,B,C,K
00001999
870.1200
81-2
Acute Dermal Toxicity-Rabbit/Rat
A,B,C,K
00147099,42642501,00259250
870.1300
81-3
Acute Inhalation Toxicity-Rat
A,B,C,K
00152556,00165855
870.2400
81-4
Primary Eye Irritation-Rabbit
A,B,C,K
00147100,00259250
870 7.500
81-5
Primary Skin Irritation
ABCK
00147101.00259250
103
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
870.2600
81-6
Dennal Sensitization
A,B,C,K
00153068
870.6200
81-8
Acute Neurotoxicity Screen in Rats
A,B,C,K
45589101, 42912401
870.6300
83-6
Developmental Neurotoxicity Study -
Cholinesterase Activity Assessment
Screening Assay
A,B,C,K
Data Gap
870.3100
82-la
90-Day Feeding - Rodent
A,B,C,K
43012701
870.3200
82-2
21-Day Dermal - Rabbit/Rat
A,B,C,K
42642501
?
82-5b
90-day neurotox - mammal
A,B,C,K
42095901,
870.4100
83-la
Chronic Feeding Toxicity - Rodent
A,B,C,K
42157601
870.4100
83-lb
Chronic Feeding Toxicity - Non-
Rodent
A,B,C,K
41503608, 41967901
870.4200
83-2a
Oncogenicity - rat
A,B,C,K
42313401
870.3700
83-3a
Developmental Toxicity
(Teratogenicity) - rat
A,B,C,K
00259810, 40534101, 42095901, 42223601, 41498301
870.3700
83-3b
Developmental Toxicity
(Teratogenicity) - rabbit
A,B,C,K
42223601, 40577301, 40444702, Data Gap
870.3800
83-4
2-Generation Reproduction - Rat
A,B,C,K
45441203, 42095901
870.4300
83-5
Combined Chronic Toxicity/
Carcinogenicity
A,B,C,K
42157601, 41967901
870.5375
84-2b
Structural chrom. aberration
A,B,C,K
40510901,
870.7485
85-1
General Metabolism
A,B,C,K
42235701, 42235702
ENVIRONMENTAL FATE
835.2120
161-1
Hydrolysis
A,B,C,K
41840601, 45714101, Data gap
835.2240
161-2
Photodegradation - Water
A,B,C,K
45651201, 41753801
835.2410
161-3
Photodegradation - Soil
A.B.C.K
45724501. 43661801
104
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
835.4100
162-1
Aerobic Soil Metabolism
A,B,C,K
43734901
835.4200
162-2
Anaerobic Soil Metabolism
A,B,C,K
Data Gap
835.4400
162-3
Anaerobic Aquatic Metabolism
A,B,C,K
43628501
835.4300
162-4
Aerobic Aquatic Metabolism
A,B,C,K
45243401
835.1240
163-1
Leaching/Adsorption/Desorption
A,B,C,K
43787501, Data gap
835.6100
164-1
Terrestrial Field Dissipation
A,B,C,K
44724501, 44724502
RESIDUE CHEMISTRY
860.1200
Directions for Use
Data gap
860.1300
171-4a
Nature of Residue in Plants
A,B,C,K
43562201, 43741901, 00162142, 40216502, 44992501, Data sap
860.1300
171-4b
Nature of Residue in Livestock
A,B,C,K
41006201, 42677501, 41006202, 42943701, 42954201, Data gap
860.1340
171-4c
Residue Analytical Method - plant
A,B,C,K
00098143, 00098190, 00041997, 00085531, 00098644, 40495201,
42399601, 40216502, 00002931, 00086910, 00090174, 0098132, 00098135,
00098137, 41065001, 41065002, 41065003, 41065004, 41065005, 41065006,
41065007, 4153601, 41503602, 41503603, 41503604, 41503605, Data sap
860.1340
171-4d
Residue Analytical Method - livestock
A,B,C,K
41006201, 41006202, 42677501, 42943701, 42954201, Data gap
860.1360
171-4m
Multiple Residue Methods
A,B,C,K
00002931, 00072406, 00090174, Data gap
860.1380
171-4e
Storage stability
A,B,C,K
42399601, 43762601, Data Gap
860.1480
171-4]
Residues on Meat/Milk/Poultry/Egg
A,B,C,K
Data Gap
860.1500
171-4k
Cropfield Residue (general)
A,B,C,K
00045165, 00089408
860.1500
171-4k
Cropfield Residue (Celery)
A,B,C,K
00090157, 00098135, 00098190
860.1500
171-4k
Cronfield Residue (Lettuce)
A.B.C.K
41503601
105
-------
Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
860.1500
171-4k
Cropfield Residue (Cabbage)
A,B,C,K
42399603
860.1500
171-4k
Cropfield Residue (Bean, Dry and
Succulent)
A,B,C,K
41065004, 41065005,43835201
860.1500
171-4k
Cropfield Residue (Soybean)
A,B,C,K
00162142, 40216502, 41065006, 43835208
860.1500
171-4k
Cropfield Residue (Pea)
A,B,C,K
41503602
860.1500
171-4k
Cropfield Residue (Tomatoes)
A,B,C,K
42399605, 00098190
860.1500
171-4k
Cropfield Residue(Cucumber)
A,B,C,K
42399604
860.1500
171-4k
Cropfield Residue (Apple)
A,B,C,K
00075880, 00089610, 00098140, 43757401, 43813101, 43846301, 447244505,
44992501, Data Gap
860.1500
171-4k
Cropfield Residue (Peach)
A,B,C,K
00045165, 00089408, 00098190, 00098132, 00098150, 43759101, 44550814,
44724503, Data Gap
860.1500
171-4k
Cropfield Residue (Strawberry)
A,B,C,K
00098150, 43762601, 43762602, 44550816, 44724504, 45560301, 00045165,
00098190,
Cereal Grains Grou
p
860.1500
171-4k
Cropfield Residue (Sweet Corn)
A,B,C,K
41065003, 43835202
860.1500
171-4k
Cropfield Residue (Field Corn)
A,B,C,K
41065002
860.1500
171-4k
Cropfield Residue (Wheat)
A,B,C,K
00162142, 40216502, 41065007, 43835210
Forage, Fodder, and Straw of Cereal Grains Group
860.1500
171-4k
Cropfield Residue (Field Corn)
A,B,C,K
41065002, 43835206
860.1500
171-4k
Cropfield Residue (Sweet Corn,)
A,B,C,K
41065003
860.1500
171-4k
Cropfield Residue (Wheat, Forage,
Hay, and Straw)
A,B,C,K
00162142, 40216502, 41065007
Non-Grass Animal Feeds (Forage, Fodder, Straw, and Hay) Group
860.1500
171-4k
Cropfield Residue (Alfalfa)
A,B,C,K
42399602
860.1500
171-4k
Cropfield Residue (Sugar and table
beets)
A,B,C,K
41503604, 41503605
106
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Appendix B.
Data Supporting Guideline Requirements for the Reregistration of Thiram
New Guideline
Number
Old Guideline
Number
Requirement
Use Pattern
Bibliographic Citation(s)
860.1500
171-4k
Cropfield Residue (Safflower)
A,B,C,K
41503603
860.1500
171-4k
Cropfield Residue (banana)
A,B,C,K
00047581, 00098137, 00098143
860.1500
171-4k
Cropfield Residue (bulb and green
onion)
A,B,C,K
00041997, 00085531, 43835203, 43835204
860.1500
171-4k
Cropfield Residue (Cotton)
A,B,C,K
00162142, 41065001, 40216502
860.1500
171-4k
Seed Crops- Multiple
A,B,C,K
41065001, 41065002, 41065003, 41065004, 41065005, 41065006, 41065007,
41503601, 41503602, 41503603, 41503604, 41503605, 42399602, 42399603,
4239904, 42399605, 43835201, 43835202, 43835203, 43835204
860.1520
171-4 L
Processed Food/Feed - Crops with Seec
Treatment
A,B,C,K
43835205, 43835206, 43835207, 43835208, 43835209, 43835210
860.1520
171-4 L
Processed Food/Feed (cotton)
A,B,C,K
43835205
860.1520
171-4 L
Processed Food/Feed (Field corn)
A,B,C,K
43835206
860.1520
171-4 L
Processed Food/Feed (Safflower)
A,B,C,K
43835207
860.1520
171-4 L
Processed Food/F eed (Sugar beet)
A,B,C,K
43835209
860.1520
171-4 L
Processed Food/Feed (Soybean)
A,B,C,K
43835208
860.1520
171-4 L
Processed Food/F eed (Wheat)
A,B,C,K
43835210
860.1520
171-4 L
Processed Food/Feed (Apples)
A,B,C,K
43846301
860.1850
Confined Rotational Crops
A,B,C,K
43974091
107
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108
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Appendix C: Technical Support Documents
Additional documentation in support of this RED is maintained in the OPP docket, located in Room 119,
Crystal Mall #2, 1801 S. Bell St., Arlington, VA. It is open Monday through Friday, excluding legal holidays,
from 8:30 a.m. to 4:00 p.m.
The docket initially contained preliminary risk assessments and related documents as of January 26, 2004.
Sixty days later the first public comment period closed. The EPA then considered comments, revised the risk
assessment, and added the formal "Response to Comments" documents and the revised risk assessments to
the docket on July 2, 2004. Following a third 60-day comment period, EPA further revised the EFED risk
assessment, and added formal "Response to Comments" documents.
All documents, in hard copy form, may be viewed in the OPP docket room or downloaded or viewed via
the Internet at the following site:
http://docket.epa.gov/edkpub/index.jsp
These documents include:
Thiram Revised HED Chapter of the Reregistration Eligibility Decision Document (RED). December 16,
2003.
Thiram. [HED] Response to Phase 5 Comments. September 20, 2004.
Thiram Revised Phase 5 Occupational and Residential Exposure Assessment and Recommendations for the
Reregistration Eligibility Decision Document. April 24, 2003.
EFED Revision of Thiram Environmental Fate Risk Assessment in Response to Phase 5 Public Comment for
Thiram (PC Code 079801). September 30, 2004.
EFED Response to Public Comment for Thiram (PC Code 079801). September 30, 2004.
Addendum to Preliminary Analysis of Thiram Use, Usage, and Alternatives. October 6, 2004.
Thiram - [BEAD] Response to Phase 5 Comments. October 6, 2004.
109
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110
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Appendix D. CITATIONS CONSIDERED TO BE PART OF THE DATA BASE
SUPPORTING THE REREGISTRATION DECISION (BIBLIOGRAPHY)
GIITDE TO APPENDIX D
1. CONTENTS OF BIBLIOGRAPHY. This bibliography contains citations of all studies considered
relevant by EPA in arriving at the positions and conclusions stated elsewhere in the Reregistration
Eligibility Document. Primary sources for studies in this bibliography have been the body of data
submitted to EPA and its predecessor agencies in support of past regulatory decisions. Selections from
other sources including the published literature, in those instances where they have been considered, are
included.
2. UNITS OF ENTRY. The unit of entry in this bibliography is called a "study." In the case of published
materials, this corresponds closely to an article. In the case of unpublished materials submitted to the
Agency, the Agency has sought to identify documents at a level parallel to the published article from
within the typically larger volumes in which they were submitted. The resulting "studies" generally have
a distinct title (or at least a single subject), can stand alone for purposes of review and can be described
with a conventional bibliographic citation. The Agency has also attempted to unite basic documents and
commentaries upon them, treating them as a single study.
3. IDENTIFICATION OF ENTRIES. The entries in this bibliography are sorted numerically by Master
Record Identifier, or "MRID" number. This number is unique to the citation, and should be used
whenever a specific reference is required. It is not related to the six-digit "Accession Number" which has
been used to identify volumes of submitted studies (see paragraph 4(d)(4) below for further explanation).
In a few cases, entries added to the bibliography late in the review may be preceded by a nine character
temporary identifier. These entries are listed after all MRID entries. This temporary identifying number
is also to be used whenever specific reference is needed.
4. FORM OF ENTRY. In addition to the Master Record Identifier (MRID), each entry consists of a
citation containing standard elements followed, in the case of material submitted to EPA, by a description
of the earliest known submission. Bibliographic conventions used reflect the standard of the American
National Standards Institute (ANSI), expanded to provide for certain special needs.
a Author. Whenever the author could confidently be identified, the Agency has chosen to show a
personal author. When no individual was identified, the Agency has shown an identifiable
laboratory or testing facility as the author. When no author or laboratory could be identified, the
Agency has shown the first submitter as the author.
b. Document date. The date of the study is taken directly from the document. When the date is
followed by a question mark, the bibliographer has deduced the date from the evidence contained in
the document. When the date appears as (1999), the Agency was unable to determine or estimate
the date of the document.
c. Title. In some cases, it has been necessary for the Agency bibliographers to create or enhance a
document title. Any such editorial insertions are contained between square brackets.
d. Trailing parentheses. For studies submitted to the Agency in the past, the trailing parentheses
include (in addition to any self-explanatory text) the following elements describing the earliest
known submission:
111
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Submission date. The date of the earliest known submission appears immediately following
the word "received."
Administrative number. The next element immediately following the word "under" is the
registration number, experimental use permit number, petition number, or other
administrative number associated with the earliest known submission.
Submitter. The third element is the submitter. When authorship is defaulted to the
submitter, this element is omitted.
Volume Identification (Accession Numbers). The final element in the trailing parentheses
identifies the EPA accession number of the volume in which the original submission of the
study appears. The six-digit accession number follows the symbol "CDL," which stands for
"Company Data Library." This accession number is in turn followed by an alphabetic suffix
which shows the relative position of the study within the volume.
112
-------
MRID
00001416
00001417
00001419
00001448
00001452
00001453
00001458
00001472
00001473
00001474
CITATION
Natti, J.J. (1965) Fungicide Treatments of Soil for Control of Bean Root Rots.
(Unpublished study received Jul 8, 1968 under 8F0657; prepared by New York State
Agricultural Station, Dept. of Plant Pathology, submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, Del.; CDL:091146-M)
E.I. du Pont de Nemours & Company, Incorporated (1966) Demosan Efficacy
Studies on Beans. (Unpublished study received Jul 8, 1968 under 8F0657;
CDL:091146-N)
E.I. du Pont de Nemours & Company, Incorporated (1966) Demosan Efficacy
Studies on Peas, Soybeans and Sugarbeets. (Unpublished study received Jul 8,
1968 under 8F0657; CDL:091146-P)
Paulus, A.O. (1972) Cotton Seedling Trial-Rhizoctonia. (Unpublished study
including letter dated Jun 29, 1972 from A.O. Paulus to Bill Reische, received
Sep 5, 1974 under 352-312; prepared by Univ. of California—Riverside,
Agricultural Extension Service, submitted by E.I. du Pont de Nemours & Co., Inc.,
Wilmington, Del.; CDL:002466-G)
E.I. du Pont de Nemours & Company, Incorporated (1972) Data Supporting the
Use of Demosan®T Seed Fungicide as a Cottonseed Treatment.
(Unpublished study received Apr 3, 1972 under 352-360; CDL:003095-A)
E.I. du Pont de Nemours & Company, Incorporated (1975) Data Supporting the
Use of "Demosan" T Seed Fungicide on Beans. (Unpublished study received
Feb 10, 1975 under 352-360; CDL:221888-A)
Worf, G.L.; Ahrens, RW. (1971) Results of 1970-71 (Typhula) Snow Mold Trials
in Wisconsin. (Unpublished study received Jan 10, 1972 under 352-359; prepared by
Univ. of Wisconsin, Dept. of Plant Pathology, submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, Del.; CDL:003093-G)
E.I. du Pont de Nemours & Company, Incorporated (1965) Summary of Field
Results with Seed Application of Chloroneb (S.F. 1823-75W) on Acid Delinted
Cotton. (Unpublished study received Apr 3, 1972 under 352-360; CDL:003095-C)
E.I. du Pont de Nemours & Company, Incorporated (1970) Evaluation of Two
Rates of Demosan 65 W on Acid Delinted Cottonseed in Greenhouse Planting in
1970. (Unpublished study received Apr 3, 1972 under 352-360; CDL:003095-E)
E.I. du Pont de Nemours & Company, Incorporated (1971) Evaluation of Three
Rates of "Demosan" Chloroneb on Acid and Reginned Cottonseed in Pythium and
Rhizocbonia Boosted Soil in Greenhouse Plantings in 1971. (Unpublished study
113
-------
received Apr 3, 1972 under 352-360; CDL:003095-F)
00001475
00001478
00001479
00001484
00001485
00001487
00001489
00001490
00001491
00001492
Gillham, L.B. (1971) Farmer Cottonseed Treatment Trials 1971: Acid Delinted
Cottonseed. (Unpublished study received Apr 3, 1972 under 352-360; submitted by
E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:003095-H)
Kappelman, A. (1971) 1971 Regional Cottonseed Treatment Test in Alabama.
(Unpublished study received Apr 3, 1972 under 352- 360; submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, Del.; CDL:003095-K)
Welch, A.W. (1971) 1971 Regional Seed Treatment Tests in North Carolina.
(Unpublished study received Apr 3, 1972 under 352- 360; submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, Del.; CDL:003095-L)
E.I. du Pont de Nemours & Company, Incorporated (1971) Evaluation of Selected
1971 Regional Cottonseed Treatment Samples in Laboratory: Pythium and
Rhizoctonia Boosted Soil Plantings, December, 1971. (Unpublished study received
Apr 3, 1972 under 352-360; CDL:003095-Q)
E.I. du Pont de Nemours & Company, Incorporated (1971) Summary of
"Demosan" T Performance in the 1971 Regional Cottonseed Treatment Trials.
(Unpublished study received Apr 3, 1972 under 352-360; CDL:003095-R)
E.I. du Pont de Nemours & Company, Incorporated (1966) Evaluation of
"Demosan" 65W Chlorone b Fungicide as Seed Overcoat of Blackeye Peas for
Protection Against Rhizoctonia in Florida in 1966. (Unpublished study received Feb 10,
1975 under 352-360; CDL:221888-C)
Krause, K.L. (1966) Evaluation of "Demosan" and Insecticide as Seed Treatment
Additives to Ferry Morse E5221 White Bush Beans in Greenhouse Planting of
Regular Seed Rot Test Soil and in Rhizoctonia Boosted Soil in 1966. (Unpublished
study received Feb 10, 1975 under 352-360; submitted by E.I. du Pont de Nemours
& Co., Inc., Wilmington, Del.; CDL:221888-E)
Krause, K.L. (1966) Effect of "Demosan" and Insecticide 1179 as Additive Seed
Treatments To"Arasan" 75 on Piota Beans in Greenhouse Plantings in 1966.
(Unpublished study received Feb 10, 1975 under 352-360; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:221888-F)
deZeeuw, D.J.; Crum, RA. (1972) 1972 Seed Treatment Fungicide Trials on Wax
Beans and Sugarbeets. (Unpublished study received Feb 10, 1975 under 352-360;
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.;
CDL:221888-G)
E.I. du Pont de Nemours & Company, Incorporated (1972) Performance of
114
-------
"Demosan" T on Henderson Bush Lima Beans in Greenhouse Planting in
Rhizoctonia Boosted Soil in 1972-Trial 1. (Unpublished study received Feb 10,
1975 under 352-360; CDL:221888-H)
00001493 Krause, K.L. (1972) Performance of "Demosan" T on Five Lots of Beans in
Greenhouse Planting in Pythium Boosted Soil in 1972- Trial 1. (Unpublished study
received Feb 10, 1975 under 352-360; submitted by E.I. du Pont Nemours & Co.,
Inc., Wilmington, Del.; CDL:221888-1)
00001494 Krause, K.L. (1973) Performance of Demosan ® T. on Henderson Bush Lima
Beans in Greenhouse Plantings in Pythium Boosted Soil in 1973. (Unpublished study
received Feb 10, 1975 under 352-360; submitted by E.I. du Pont de Nemours &
Co.,Inc., Wilmington, Del.; CDL:221888-N)
00001517 DeZeeuw, D.J.; Guyer, G.E.; Andersen, A.L. (1956) Fungicide and insecticide seed
treatments of peas and beans, 1953-55. Plant Disease Reporter 40(8):727-733.
(Also in unpublished submission received Oct 26, 1956 under 400-33; submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:231184-A)
00001737 Owen, J.H. (1962) Cotton Soil Fungicide Test, Tifton, Georgia, 1962. (Unpublished
study received Dec 16, 1964 under 1258-740; prepared in cooperation with U.S.
Agricultural Research Service, Crops Research Div., Georgia Coastal Plain Experiment
Station; submitted by Olin Mathieson Chemical Corp., New York, N.Y.; CDL:005764-
W)
00001738 Owen, J.H. (1962) Soil Fungicide Plot-Cotton Seedling Dam ping-Off. (Unpublished
study received Dec 16, 1964 under 1258-740, submitted by Olin Mathieson Chemical
Corp., New York, N.Y.; CDL: 005764-X)
00001750 Bird, L.S. (1965) In-Covering Soil Fungicides for Cotton Seedling Disease Control
Statewide and College Station Tests. (Unpublished study received Sep 21, 1965
under 1258-740; prepared by Texas A & M Univ., Texas Agricultural Experiment
Station in cooperation with U.S. Agricultural Research Service, Crops Research
Div., submitted by Olin Mathieson Chemical Corp., New York, N.Y.; CDL:005767-F)
00001832 Everson, L.E. (1967) Warm & Cold Germination Tests for Olin Agricultural
Division: Terrazole. (Unpublished study including letter dated Oct 23, 1967 from
L.E. Everson to Tom G.Roberts and Harvey H. Klein, received Feb 16, 1968 under
1258-813; prepared by Iowa State Univ., Cooperative Extension Service, Seed
Laboratory, submitted by Olin Corp., Stamford, Conn.; CDL:005784-A)
00001834 Amador, J. (1967) Seed Treatment Evaluations: TX 2+1, Terrazole 50% Sol.:
FTFDRNo. TGR 56-1 Final. (Unpublished study received Feb 16, 1968 under
1258-813; submitted by Olin Corp., Stamford, Conn.; CDL:005784-C)
00001836 Mueller, P. (1967) Yoakum, Prairie View and Stephenville Seed Treatment.
115
-------
00001839
00002004
00002039
00002236
00002826
00002858
00002859
00002871
00002905
00002906
(Unpublished study including letter dated Apr 11, 1967 from P. Mueller to T.G.
Roberts, received Feb 16, 1968 under 1258-813; submitted by Olin Corp.,
Stamford,Conn.; CDL: 005784-E)
Bell, D.K. (1965) Peanut Seed Treatment Trials, 1965. (Unpublished study received
Feb 16, 1968 under 1258-813; prepared by Univ. of Georgia, Georgia Coastal Plain
Experiment Station, Plant Pathology Dept., submitted by Olin Corp., Stamford,
Conn.; CDL: 005784-K)
Hercules, Incorporated (1969) Compatibility Studies with Hercules 14503.
(Unpublished study received Jan 30, 1969 under 9G0802; CDL:093 111 -I)
Norton, R.J. (1968) Effectiveness of Selected Commercial Fungicides Applied Alone
and in Combination with H-14503: Report No. 1-68. (Unpublished study received Jan
30, 1969 under 9G0802; submitted by Hercules, Inc., Agricultural Chemicals,
Wilmington, Del.; CDL:093111-U)
Sinclair, J. (1964) Soil Fungicide Tests-Cotton. (Unpublished study received Feb 16,
1964 under 1258-740; prepared by Louisiana State Univ., Agricultural Experiment
Station, Dept. of Plant Pathology, submitted by Olin Mathieson Chemical Corp., New
York, N.Y.; CDL:005764-H)
Mankin, C.J.; Wood, L.S. (1970) Olin Seed Treatment Trials in the Greenhouse.
(Unpublished study received Sep 1, 1971 under 1258-818; prepared by South Dakota
State Univ.-Brookings, Plant Science Dept., submitted by Olin Corp., Stamford, Conn.;
CDL: 005785-B)
Uniroyal Chemical (1972) Stability of Vitavax®I on Treated Seed (Grain and
Corn). (Unpublished study received Sep 27, 1972 under 3F1318; CDL:093547-M)
Uniroyal Chemical (1971) Reasoning in Support of the Petition: Vitavax.
(Unpublished study including revised section G-5, received Sep 27, 1972 under
3F1318; CDL:093547-O)
Uniroyal Chemical (1975) Toxicity of Vitavax to Fish and Wildlife. (Unpublished
study received Sep 28, 1976 under 400-130; CDL: 230406-C)
Uniroyal Chemical (1974) The Effects of EPA Tolerance Pesticides upon the
Recovery of Vitavax®I Residues from Peanuts. (Unpublished study received on
unknown date under 4F1499; prepared in cooperation with Morse Laboratories, Inc.;
CDL:093979-F)
Uniroyal Chemical (1974) Tabular Summary of Performance Data: Emergence (Stand
Counts): Vitavax Fungicide. (Unpublished study received May 1, 1974 under 4F1499;
CDL:094551-J)
116
-------
00002907
00002909
00002912
00002913
00002914
00002915
00002916
00002923
00002928
00002929
Lyle, J.A.; Brogden, C.A. (1970) 1970 Florunner Peanut Seed Treatment.
(Unpublished study received May 1, 1974 under 4F1499; prepared by Auburn
Univ., Agricultural Experiment Station, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:094551-K)
Oklahoma State University (1969) Research Progress Report—1968: Peanut Disease
Control: Progress Report P-612. (Unpublished study received May 1, 1974 under
4F1499; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:094551-N)
White, L.W. (1969) Peanut Seed Treatment #2. (Unpublished study received on
May 1, 1974 under 4F1499; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:094551-S)
Home, C.W. (1971) Results of 1971 Extension Peanut Disease Control
Demonstrations Conducted at Stephenville, Mason and Floresville, Texas.
(Unpublished study received May 1,1974 under 4F1499; prepared by Texas A & M
Univ., Texas Agricultural Extension Service, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:094551-T)
Home, C.W.; Philley, G.L.; Smith, L.R. (1972) Results of 1972 Extension Peanut
Disease Control Demonstrations Conducted at Mason, Grapeland, Dublin, and
Floresville, Texas. (Unpublished study received May 1, 1974 under 4F1499; preparedby
Texas A & M Univ., Texas Agricultural Extension Service, submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:094551-U)
Harrison, A.L.; Smith, O.; Simpson, C.E. (1970) Small Plot Seed Treatment
Tests—1970. (Unpublished study received May 1, 1974 under 4F1499; prepared by
Texas A & M Univ., Plant Disease Research Station, Prairie View Experiment
Station and Tarleton Experiment Station, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:094551-V)
Texas A & M University, Plant Disease Research Station (1969) 1969 Fall Peanut
Seed Treatment Test. (Unpublished study received on May 1, 1974 under 4F1499;
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:094551-W)
Mastri, C. (1970) Report to Uniroyal Chemical, Division of Uniroyal, Inc.: Four-Day
Fish Toxicity Study on Three Samples of Vitavax Seed Protectants: IBT No. A8585.
(Unpublished by Uniroyal Chemical, Bethany, Conn.; CDL:230400-G)
Uniroyal Chemical (1972) Residues in PPM: Vitavax. (Unpublished study received
on unknown date under 0F0939; CDL:094582-B)
Chin, W.T.; Dannals, L.E.; Stone, G.M.; Kucharczyk, N. (1972) 14C Residues in
Cottonseed Grown from Seed Treated with Vitavax(R) 200 and Vitavax 300 Seed
Protectant Containing Vitavax 14C (Phenyl or Hetero Tag): Project No. 7121.
117
-------
00002930
00002931
00002932
00002933
00002934
00002935
00002939
00002948
00002949
00002950
(Unpublished study received on unknown date under 0F0939; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:094582-C)
Uniroyal Chemical (1972) Residues in PPM: Vitavax. (Unpublished study received
on unknown date under 0F0939; CDL:094582-E)
Keppel, G.E. (1971) Collaborative study of the determination of Dithiocarbamate
residues by a modified Carbon disulfide evolution method. Journal of the AO AC
Association of Official Analytical Chemists 54(3):528-531. (Also in unpublished
submission received on unknown date under 0F0939; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:094582-G)
Wells, J.C. (1969) Peanut Seed Treatment Tests. (Unpublished study including letter
dated Mar 25, 1970 from J.C. Wells to Dave Benson, received Apr 6, 1970 under
0F0939; prepared by North Carolina State Univ., Agricultural Extension Service, Dept.
of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.; CDL:094582-H)
Wadsworth, D.F. (1969) Peanut Disease Research: Preliminary Report.
(Unpublished study received Apr 6, 1970 under 0F0939; prepared by Oklahoma
State Univ., Botany and Plant Pathology Dept., submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:094582-I)
Harvey, J.E. (1970) Vitavax Peanut Seed Treatment—1969. (Unpublished study
received Apr 6, 1970 under 0F0939; prepared by Gold Kist Peanuts, submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:094582-J)
Chin, W.T.; Dannals, L.E.; Kucharczyk, N. (1972) Environmental Fate Studies on
Vitavax®: Status Report on PR 70-15. (Unpublished study received Mar 6, 1972
under 2F1191; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:093515-A)
Uniroyal Chemical (1970) Vitavax Handling Toxicity Studies. (Unpublished study
received Oct 9, 1973 under 3F1318; CDL:092254-C)
Uniroyal Chemical (1972) Seed Rots and Seedling Disease Control Data Summary.
(Unpublished study received Dec 23, 1972 under 3F1318; CDL:092253-B)
Davis, R.A. (1968) Performance of Vitavax-Maneb and Vitavax-Thiram
Combinations as Corn Seed Protectants. (Unpublished study received Dec 23, 1972
under 3F1318; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:092253-C)
Simpson, W.R; Fenwick, HS. (1971) Suppression of corn head smut with Carboxin
seed treatments. Plant Disease Reporter 55(6): 501-503. (Also in unpublished
submission received Dec 23, 1972 under 3F1318; submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:092253-E)
118
-------
00002951
Uniroyal Chemical (1972) Field Performance Report. (Unpublished study including
report, received Dec 23, 1972 under 3F1318; CDL:092253-F)
00002952
00002953
00002954
00002955
00002956
00002962
00002963
00002964
00002972
00002973
University of Illinois, Department of Plant Pathology (1971) Fungicide Seed
Treatment: ProjectF-1. (Unpublished study received Dec 23, 1972 under 3F1318;
submitted by Uniroyal Chemical. Bethany, Conn.; CDL:092253-G)
Ullstrup, A.J. (1971) A Report of the Effects of Seed Treatments on Stand, Smut,
SCLB and Yield in Tms and Normal Cytoplasm Corn. (Unpublished study including
letter dated Oct 25, 1971 from A.J. Ullstrup to Keith M. McReynolds, received
Dec 23, 1972 under 3F1318; prepared by Purdue Univ., Dept. of Botany and Plant
Pathology, submitted by Uniroyal Chemical, Bethany, Conn.; CDL:092253-I)
Uniroyal Chemical (1971) Seed Corn Treatment Experiment, Washington, Iowa.
(Unpublished study received Dec 23, 1972 under 3F1318; CDL:092253-K)
Futrell, M.C. (1971) New Concepts in Chemical Seed Treatment of Agronomic
Crops. (Unpublished paper presented at the 63rd annual meeting of the American
Society of Agronomy; Aug 18, 1971; New York, N.Y.; available from author, U.S.
Agricultural Research Service, Plant Science Division in cooperation with the
Mississippi Agricultural Experiment Station, State College, Miss.; Also in
unpublished submission received Dec 23, 1972 under
3F1318; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:092253-M)
Uniroyal Chemical (1972) Control of Helminthosporium maydis Race T in Corn Seed
by Chemical Seed Treatment. (Unpublished study received Dec 23, 1972 under
3F1318; CDL:092253-N)
Uniroyal Chemical (1971) Residue Data. (Unpublished study received May 8, 1972
under 2F1191; CDL:091003-S)
Mankin, C.J.; Wood, L.S. (19??) Oats: Seedling Blight, Pythium, Fusarium.
(Unpublished study received on unknown date under 9G0819; prepared by South
Dakota State Univ., submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:091418-D)
Amy, D.C. (1970) 1970 Seed Treatment: Oats Smuts (Covered & Loose) and Barley
Loose Smut: Madison, Wisconsin. (Unpublished study received on unknown date under
9G0819; prepared by Univ. of Wisconsin, Dept. of Plant Pathology, submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:091418-E)
Walz, A.W. (1969) Winter Wheat: Smut (Ustilago tritici). (Unpublished study
received Jun 14, 1969 under 9G0819; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:091419-D)
Hansing, E.D. (1970) Effect of Seed Treatment on Control of Seed Decay, Seedling
119
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00002976
00002983
00002984
00002985
00002986
00002987
00002999
00003004
00003006
00003007
00003008
Blight, and Bunt of Wheat, Manhattan, Kansas, 1970. (Unpublished study including
report, received on unknown date under 9G0819; prepared by Kansas State Univ.,
Dept. of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:091419-E)
Walz, A.W.; Roberts, T.G. (1970) Field Results on Winter Wheat: Nebraska, Kansas,
Oklahoma, Texas 1970. (Unpublished study received on unknown date under 9G0819;
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:091419-F)
Benson, D.A.; Dunnigan, D.J.; Davis, RA. (1970) Barley Loose Smut Test-
Sanford, Florida: February 1970. (Unpublished study received on unknown date
under 9G0819; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:091419-H)
Uniroyal Chemical (1977) Vitavax-25 DB~Wheat. (Unpublished study received
Jan 10, 1978 under 400-115; CDL:232622-A)
Uniroyal Chemical (1977) Vitavax-25 DB~Oats. (Unpublished study received
Jan 10, 1978 under 400-115; CDL:232622-B)
Uniroyal Chemical (1977) Vitavax-25 DB~Barley. (Unpublished study received
Jan 10, 1978 under 400-115; CDL:232622-C)
Uniroyal Chemical (1977) Vitavax-25 DB~Phytotoxicity. (Unpublished study
received Jan 10, 1978 under 400-115; CDL:232622-D)
Mclntire, S. (1971) 1971 Cottonseed Treatment Tests, Senatobia Field Station.
(Unpublished study received Apr 12, 1972 under 400-80; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL: 023352-A)
Uniroyal Chemical (1975) Field Evaluation Report. (Unpublished study received
Jul 15, 1976 under 400-118; CDL:224932-D)
Uniroyal Chemical (1975) Toxicity of Vitavax to Fish and Wildlife. (Unpublished
study received Jul 15, 1976 under 400-118; CDL:224935-C)
Uniroyal Chemical (1977) Stand Counts. (Unpublished study received
Dec 20, 1977 under 400-116; CDL:232528-C)
Chevron Chemical Company (1976) Rice Seed Treatment, What's New From
Ortho: A Seed Treatment Which Provides "Good" Helminthosporium oryzae
Control. (Unpublished study received Dec 20, 1977 under 400-116; submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:232528-E)
Rush, M.C. (1977) Special Helminthosporium oryzea Tests. (Unpublished study
received Dec 20, 1977 under 400-116; prepared by Louisiana State Univ. and
120
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Agricultural and Mechanical College, Agricultural Experiment Station, Dept. of
Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.; CDL:232528-H)
00003009 Uniroyal Chemical (1977) Toxicology: Vitavax-200 Flowable. (Unpublished study
received Jul 14, 1978 under 400-112; CDL:235042A)
00003010 Imlay, P. (1977) Report: The Acute Dermal LD50 of Vitavax-200 Flowable
Fungicide on New Zealand Albino Rabbits. (Unpublished study received Jul 14, 1978
under 400-112; prepared by Cannon Laboratories, Inc., submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:235042-B)
00003011 Babish, J.G. (1977) Vitavax-200 Flowable Fungicide: BL #8229: Acute Inhalation
Study in Rats. (Unpublished study received Jul 14, 1978 under 400-112; prepared by
Food and Drug Research Laboratories, Inc., submitted by Uniroyal Chemical,
Bethany, Conn.; CDL: 235042-C)
00003012 Matthews, R.J. (1973) Acute LD50 Rats, Oral: Final Report. (Unpublished study
received Jul 14, 1978 under 400-112; prepared by Pharmakon Laboratories,
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:235042-D)
00003013 Babish, J.G. (1976) Vitavax 200 Flowable Fungicide: 076008: Rabbit Eye Irritation
Study. (Unpublished study received Jul 14, 1978 under 400-112; prepared by Food
and Drug Research Laboratories, Inc., submitted by Uniroyal Chemical, Bethany,
Conn.; CDL: 235042-E)
00003014 Babish, J.G. (1976) Vitavax 200 Flowable Fungicide: 076008: Primary Skin Irritation
Study with Rabbits. (Unpublished study received Jul 14, 1978 under 400-112; prepared
by Food and Drug Research Laboratories, Inc., submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:235042-F)
00003015 Babish, J.G. (1977) Vitavax 200 Flowable Fungicide: G 037132 JS; BL 8538: Acute
Dermal Toxicity Study in Rabbits. (Unpublished study received Jul 14, 1978 under
400-112; prepared by Food and Drug Research Laboratories, Inc., submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:235042-G)
00003016 Uniroyal Chemical (1978) Vitavax-200 Flowable Fungicide: Soybeans. Summary of
studies 235936-G and 235936-H. (Unpublished study received Nov 14, 1978 under
400-112; CDL:235936-C)
00003017 Uniroyal Chemical (1976) Soybeans: Vitavax-200 Flowable Fungicide. (Unpublished
study received Nov 14, 1978 under 400-12; CDL: 235936-D)
00003018 Uniroyal Chemical (1978) Germination Results-Soybeans. Summary of studies
235936-T through 235936-V. (Unpublished study received Nov 14, 1978 under
400-112; CDL:235936-E)
121
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00003019 Stuckey, R.E. (1978) Soybean Seed Treatment, 1978. (Unpublished study including
letter dated Jul 19, 1978 from R.E. Stuckey to Roy C. Parker, received Nov 14,
1978 under 400-112; prepared by Univ. of Kentucky, Cooperative Extension Service,
Dept. of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.; CDL:
235936-T)
00003020 Illinois Crop Improvement Association (1977) Laboratory Germinations.
(Unpublished study received Nov 14, 1978 under 400-112; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:235936-V)
00003023 Chevron Chemical Company (1976) 12.05 Efficacy Data to Support Registration of
Orthocide Vitavax 20-20 S.P. for Use on Wheat, Oats and Barley Seed.
(Unpublished study received May 11, 1977 under 239-2458; CDL:230223-A)
00003051 Uniroyal Chemical (1969) Data on Seed Treatment—Soil Fungicide Test for Control of
Cotton Seedling Diseases, Athens, Georgia, 1969: Table 2. (Unpublished study received
Jun 5, 1970 under 0F0939; CDL:093245-N)
00003057 Uniroyal Chemical (1970) Appendix. (Unpublished study received Dec 21, 1971
under 400-81;CDL:050050-A)
00003074 Heitmuller, T. (1975) Acute Toxicity of Vitavax to Pink Shrimp (Penaeus duorarum)
and Fiddler Crabs (Uca pugilator). (Unpublished study received May 16, 1975 under
400-116; prepared by Bionomics—EG&G, Inc., submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:165048-A)
00003076 Uniroyal Chemical (1971) Vitavax-Fungicide: Peanut Seed Treatment Test
Summary in Combination with Captan and Thiram. Summary of studies 220663-F
through 220663-1 and 220663-N through 220663-Q. (Unpublished study received
Jun 10, 1975 under 40092; CDL:220663-D)
00003077 Wadsworth, D.F. (1968) Peanut Seed Treatment Test. (Unpublished study including
letter dated Jan 15, 1969 from D.F. Wadsworth to Tom Roberts, received Jun 10,
1975 under 400-92; prepared by Oklahoma State Univ., Dept. of Botany and Plant
Pathology, submitted by Uniroyal Chemical, Bethany, Conn.; CDL:220663-I)
00003092 Uniroyal Chemical (1973) Stability of Vitavax® on Treated Wheat and Barley
Seed. (Unpublished study received Jun 26, 1973 under 400-108; CDL:008327-D)
00003093 Uniroyal Chemical (1973) Summary of Performance Data: Vitavax.
(Unpublished study received Jun 26, 1973 under 400-108; CDL: 008327-E)
00003094 Uniroyal Chemical (1973) Field Performance Report: UNI-1088 and 1090.
(Unpublished study received Jun 26, 1973 under 400-108; CDL:008327-F)
00003095 Davis, RA. (1972) 1972 Barley Loose Smut Field Test-Bethany, Connecticut.
(Unpublished study received Jun 26, 1973 under 400-108; submitted by Uniroyal
122
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Chemical, Bethany, Conn.; CDL: 008327-G)
00003096
00003097
00003098
00003104
00003105
00003106
00003107
00003122
00003123
00003124
00003125
00003126
Walz, A.W. (1972) North Dakota Loose Smut Test. (Unpublished study received
Jun 26, 1973 under 400-108; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:008327-H)
Hansing, E.D. (1973) Effect of Seed Treatment on Control of Seed Decay and
Seedling Blight of Wheat, 1972-1973 Crop. (Unpublished study received Jun 26,
1973 under 400-108; prepared by Kansas State Univ., ?Dept. of Plant Pathology,
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:008327-I)
Pederson, V.D. (1972) Materials and Methods Used for Seed Treatment Trials in
1972. (Unpublished study received Jun 26, 1973 under 400-108; prepared by North
Dakota State Univ., submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:008327-J)
Uniroyal Chemical (1975) Summary of Performance Data: Oats: Vitavax-200
Flowable Fungicide. (Unpublished study received Apr 21, 1975 under 400-112;
CDL:220785-B)
Uniroyal Chemical (1974) Field Evaluation Report: Seed Treatment of Oats.
(Unpublished study received Apr 21, 1975 under 400-112; CDL:220785-C)
Uniroyal Chemical (1974) Field Evaluation Report: Phyto Study. (Unpublished study
received Apr 21, 1975 under 400-112; CDL: 220785-D)
Uniroyal Chemical (1974) Field Evaluation Report: Small Grain Seed Treatment.
(Unpublished study received Apr 21, 1975 under 400- 112; CDL:220785-E)
Uniroyal Chemical (1973) Summary of Performance Data-Seedling Survival (Stand
Counts). (Unpublished study received May 16, 1973 under 400-107;
CDL:003284-C)
Uniroyal Chemical (1973) Summary of Phytotoxicity Data. (Unpublished study
received May 16, 1973 under 400-107; CDL:003284-D)
Kappelman, A.J., Jr. (1972) Regional Cottonseed Treatment Test, Tallassee,
Alabama, 1972. (Unpublished study received May 16, 1973 under 400-107;
prepared by U.S. Agricultural Research Service, Southern Region, submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:003284-G)
Uniroyal Chemical (1972) Field Performance Report. (Unpublished study received
May 16, 1973 under 400-107; CDL:003284-H)
Uniroyal Chemical (1972) 1972 Regional Cottonseed Treatment Test. (Unpublished
123
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00003128
00003130
00003132
00003133
00003151
00003153
00003154
00003155
00003156
00003157
study received May 16, 1973 under 400-107; prepared in cooperation with Seed
Treatment Committee of the Cotton Disease Council; CDL:003284-I)
Uniroyal Chemical (1972) Field Phytotoxicity Evaluation. (Unpublished study
received May 16, 1973 under 400-107; CDL:003284-N)
Uniroyal Chemical (1976) Vitavax Handling Toxicity Studies. (Unpublished study
including annotated bibliography of petition materials, received May 16, 1973 under
400-107; CDL:003284-Q)
Uniroyal Chemical (1971) Toxicity of Vitavax to Fish and Wildlife. (Unpublished
study received May 16, 1973 under 400-107; CDL: 003284-S)
Iowa State University (1973) Seed Treatment on Wheat. (Unpublished study received
May 15,1973 under 476-2143; prepared by Cooperative Extension Service, Seed
Laboratory in cooperation with Corn States Hybrid Service, Inc., submitted by
Stauffer Chemical Co., Richmond, Calif.; CDL:003912-A)
Mamadou, D. (1976) Evaluation of a Soil-Plate Screening Technique in Developing
Fungicidal Control for Southern Stem Rot of Peanuts. Master's thesis, North
Carolina State Univ., Dept. of Plant Pathology. (Unpublished study including
abstract, received Sep 13, 1976 under 400-129; submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:225604-AA)
Uniroyal Chemical (1973) Summary of Performance Data: Vitavax. Summary of
studies 023365-D, 023365-M and 023365-N. (Unpublished study received Dec 5,
1973 under 400-107; CDL:023365-C)
Pederson, V.D. (1973) Wheat (Triticum aestivum), Loose Smut (Ustilago nuda),
Seedling Blight-Fusarium, Pythium and Helminthosporium spp. (Unpublished study
received Dec 5, 1973 under 400-107; prepared by North Dakota State Univ., Dept.
of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL: 023 3 65-G)
Uniroyal Chemical (1973) Field Performance and Phytotoxicity Report.
(Unpublished study received Dec 5, 1973 under 400-107; CDL:023365-H)
Johnston, R. (1973) Winter Wheat~(Triticum aestivum), Common Bunt; Tilletia
caries. (Unpublished study including letter dated Oct 1, 1973 from R. Johnston to
Donald N. Joy, received Dec 5, 1973 under 400-107; prepared by Montana State
Univ., Agricultural Experiment Station, Plant Pathology Dept., submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:023365-J)
Pederson, V.D. (1973) Barley (Hordeum vulgare), Loose Smut (Ustilago nuda),
Seedling Blight; Fusarium, Pythium and Helminthosporium spp. (Unpublished
124
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study received Dec 5, 1973 under 400-107; prepared by North Dakota State Univ.,
Dept. of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:023365-O)
00003159 Uniroyal Chemical (1973) Vitavax-200 Flowable Fungicide: Summary of Residues in
Wheat and Barley. (Unpublished study received Dec 5, 1973 under 400-107;
CDL:023365-T)
00003178 McDaniel, M.E. (1969) Uniroyal Wheat Seedling Emergence Study: College Station
and Denton, Texas: 1968-69. (Unpublished study received Mar 25, 1969 under
9G0819; prepared by Texas A & M Univ., Agricultural Experiment Station,
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:093520-R)
00003179 Goldkist Peanuts (1968) Paper Towel Germination Test-1968. (Unpublished study
received Mar 25, 1969 under 9G0819; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:093520-S)
00003180 Wadsworth, D.F. (1968) Peanut Seed Treatment Materials for 1968. (Unpublished
study including letter dated Jan 15, 1969 from D.F. Wadsworth to Tom Roberts,
received Mar 25, 1969 under 9G0819; prepared by Oklahoma State Univ., Dept. of
Botany and Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL: 093520-U)
00003181 Harrison, A.L.; Smith, O.; Langley, B.C. (1968) 1968 Peanut Seed Treatment Tests.
(Unpublished study received Mar 25, 1969 under 9G0819; prepared by Texas A & M
Univ., Plant Disease Research Station at Yoakum, Prairie View Experiment Station,
and Tarleton Experiment Station, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:093520-W)
00003199 Wadsworth, D.F.; Young, H.C., Jr.; McCoy, R.E. (1967) Progress Report: Peanut
Disease Research—1966: Processed Series P-559. (Unpublished study received
Feb 23, 1968 under 400-EX-33; prepared by Oklahoma State Univ., Dept. of Botany
and Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL: 12343 8-D)
00003203 Uniroyal Chemical (1967) Seedling Stand, Per Cent Loose Smut, and Yield (sic) of
Larker Spring Barley from Seed, Treated with Oxathiin Systemic Fungicides at
Fargo, North Dakota, in 1967. (Unpublished study received Feb 23, 1968 under
400-EX-33; CDL: 123438-1)
00003222 Uniroyal Chemical (1977) Efficacy Data for Evershield RTU-1050 Seed Protectant.
(Unpublished study received Oct 11, 1978 under KS-78/20; prepared in cooperation
with North Dakota State Univ., Kansas State Univ., and Purdue Univ., submitted by;
CDL:235366-B)
00003230 Uniroyal Chemical (1979) Vitavax® Fungicide: Agricultural Chemicals: Technical
125
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00003270
00003271
00003272
00003273
00003274
00003304
00003306
00003307
00003308
Data Sheet. (Unpublished study received Mar 20, 1979 under 400-80;
CDL:098014-A)
Krause, K.L. (1972) Performance of "Demosan" T on Wade Bush Bean in
Greenhouse Planting in Pythium and Rhizoctonia Boosted Soil in 1972—Trial 2.
(Unpublished study received Feb 10, 1975 under 352-360; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:221888-J)
Krause, K.L. (1972) Performance of "Demosan" T on Henderson Rush Lima Beans
in Greenhouse Plantings in Pythium and Rhizoctonia Boosted Soils in 1972~Trial 2.
(Unpublished study received Feb 10, 1975 under 352-360; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:221888-K)
Krause, K.L. (1972) Performance of "Demosan" T on Wade Bush Bean in
Greenhouse Planting in Pythium and Rhizoctonia Boosted Soil in 1972—Trial 3.
(Unpublished study received Feb 10, 1975 under 352-360; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:221888-L)
Krause, K.L. (1972) Performance of "Demosan" T on Henderson Bush Lima Beans
in Greenhouse Plants in Pythium and Rhizoctonia Boosted Soils in 1972—Trial 3.
(Unpublished study received Feb 10, 1975 under 352-360; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:221888-M)
Krause, K.L. (1973) Performance of DemosanA(R)I T. on Henders Bush Lima Beans in
Greenhouse Plantings in Rhizoctonia Boosted Soil in 1973. (Unpublished study
received Feb 10, 1975 under 352-360; submitted by E.I. du Pont de Nemours & Co.,
Inc.; Wilmington, Del.; CDL:221888-0)
Uniroyal Chemical (1972) Stability of Vitavax®-200 in Treated Seed (Cotton).
(Unpublished study received Jun 28, 1972 under 0F0939; CDL:094582-F)
Uniroyal Chemical (1970) Helminthosporium maydis Control by Seed Treatment,
Greenhouse Test: Bethany, Sept 28, 1970. (Unpublished study including report and
letter dated Jun 15, 1971 from R.H. Littrell to Sidney W. Fox, received Dec 23, 1972
under 3F1318; CDL:092253-D)
Uniroyal Chemical (1970) Additional Vitavax Toxicology. Summary of studies
091003-C through 091003-R. (Unpublished study received May 8, 1972 under
2F1191; CDL:091003-B)
Mastalski, K. (1970) Report to Uniroyal Chemical, Division of Uniroyal, Inc.: Acute
Oral Toxicity Study on Vitavax Seed Protectant with Thiram in Bobwhite Quail: IBT
No. J8584. (Unpublished study received May 8, 1972 under 2F1191; prepared by
Industrial Bio-Test Laboratories, Inc., submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:091003-C)
126
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00003312 Matthews, R.J. (1970) Primary Skin Irritation—Rabbits: Vitavax(R) with Thiram:
Final Report. (Unpublished study received May 8, 1972 under 2F1191; prepared by
Pharmakon Laboratories, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:091003-H)
00003315 Matthews, R.J. (1970) Acute Dermal Application-Rabbits: Vitavax® with
Thiram: Final Report. (Unpublished study received May 8, 1972 under 2F1191;
prepared by Pharmakon Laboratories, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:091003-K)
00003318 Matthews, R.J. (1970) Acute LDI50A—Rats (Oral): Vitavax® with Thiram: Final
Report. (Unpublished study received May 8, 1972 under 2F1191; prepared by
Pharmakon Laboratories, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:091003-N)
00003326 Hansing, E.D. (1972) Oats ( Avena byzantina ): Smuts; Ustilago avenue and U .
Kolleri. Pages 138-139, In Fungicide and Nematicide Tests: Results of 1972:
Volume 28. Compiled and edited by Eldon I. Zehr... et al. Winchester, Va.:
American Phytopathological Society. (Also In unpublished submission received
Apr 21, 1975 under 400-112; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:220785-F)
00003330 Matthews, R.J. (1970) Draize Eye Irritation—Rabbits: Vitavax®I with Thiram:
Final Report. (Unpublished study received Feb 18, 1972 under 400-81; prepared by
Pharmakon Laboratories, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:003260-C)
00003333 Hansing, E.D. (1972) Effect of Seed Treatment on Control of Loose and Covered
Smuts of Oats, 1972. (Unpublished study received Apr 17, 1973 under 1352-20;
prepared by Kansas State Univ., submitted by Cargill, Inc., Minneapolis, Minn.;
CDL:005870-B)
00003334 Hansing, E.D. (1972) Effect of Seed Treatment on Control of Seed Decay, Seedling
Blight, and Covered Kernel Smut of Sorghum, 1972. (Unpublished study received
Apr 17, 1973 underl352-20; prepared by Kansas State Univ., submitted by Cargill,
Inc., Minneapolis, Minn.; CDL:005870-C)
00003336 Hansford, R. (1968) Stand Count on Justin Wheat: Chart XIII. (Unpublished study
received Mar 25, 1969 under 9G0819; prepared by North Dakota State Univ.,
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:093520-K)
00003337 Bell, D.K. (1967) Peanut Seed Treatment Tests: 1967. (Unpublished study received
Feb 23, 1968 under 400-EX-33; prepared by Georgia Coastal Plain Experiment
Station, Dept. of Plant Pathology, submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:123438-C)
127
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00003341 Pederson, V.D. (1968) Chemical control of loose smut in barley. Page 4, In
Fungicidal Control of Smut Diseases of Cereals. Compiled by J.G. Moseman.
Beltsville, Md.: U.S. Dept. of Agriculture. (U.S. Agricultural Research Service,
Crops Research Div., CR 42-68; Also in unpublished submission including glossary,
received Mar 25, 1969 under 9G0819; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:093520-AE)
00003342 Kiesling, R.L. (1968) Chemical control of wheat and barley loose smut. Pages 5-7,
In Fungicidal Control of Smut Diseases of Cereals. Compiled by J.G. Moseman.
Beltsville, Md.: U.S. Dept. of Agriculture. (U.S. Agricultural Research Service,
Crops Research Div., CR 42-68; also In unpublished submission including glossary,
received Mar 25, 1969 under 9G0819; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:093520-AF)
00003344 Hebert, T.T. (1968) Effect of chemical treatments on the control of loose smut in
barley. Pages 9-11, In Fungicidal Control of Smut Diseases of Cereals. Compiled by
J.G. Moseman. Beltsville, Md.: U.S. Dept. of Agriculture. (U.S. Agricultural
Research Service, Crops Research Div., CR 42-68; also In unpublished submission
including glossary, received Mar 25, 1969 under 9G0819; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:093520-AH)
00003349 Edgington, L.V. (1968) Chemotherapy of loose smut of barley in Canada. Pages
20-21, In Fungicidal Control of Smut Diseases of Cereals. Compiled by J.G.
Moseman. Beltsville, Md.: U.S. Dept. of Agriculture. (U.S. Agricultural Research
Service, Crops Research Div., CR 42-68; also In unpublished submission including
glossary, received Mar 25, 1969 under 9G0819; submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:093520-AM)
00003353 Kline, D.M. (1968) Effectiveness of fungicides in controlling barley loose smut. Page
28, In Fungicidal Control of Smut Diseases of Cereals. Compiled by J.G. Moseman.
Beltsville, Md.: U.S. Dept. of Agriculture. (U.S. Agricultural Research Service, Crops
Research Div., CR 42-68, also In unpublished submission including glossary, received
Mar 25, 1969 under 9G0819; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL: 093 520-AQ)
00004235 Wilbur-Ellis Company (1978) Acala SJ 2 Cotton Seedling Survival and Emergence
after Fungicide Treatment. (Unpublished study received Feb 6, 1979 under 2935-
413; CDL:234333-B)
00004244 Hathaway, D. (1970) Report to Uniroyal Chemical, Division of Uniroyal, Inc.: Acute
Dust Inhalation Toxicity Study on Vitavax Seed Protectant with Thiram: IBT No.
N8586. (Unpublished study received May 8, 1972 under 2F1191; prepared by
Industrial BioTest Laboratories, Inc., submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:091003-F)
128
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00004901
00004902
00004903
00004905
00004975
00004976
00004977
00004978
00005530
Samuel J. Milazzo Manufacturing Company (1967) Ten Day Test for Milazzo
Company Animal Chaser. (Unpublished study received Sep 12, 1967 under 8218-1;
prepared in cooperation with United States Testing Co., Inc. and Hermel
Exterminating; CDL:224446-A)
Hunsberger, J.F. (1969) Testing Program. (Unpublished study received Oct 28, 1969
under 8218-1; prepared by Allentown Testing Laboratories, Inc., submitted by
Samuel J. Milazzo Co.,Pittston, Pa.; CDL:224446-B)
Niper, R. (1963) Milazzo Brand Animal Chaser Test No. 1. (Unpublished study
including letter dated Dec 9, 1963 from R. Niper to Samuel J. Milazzo, received
Dec 17, 1963 under 8218-1; prepared by Monroe County Society for the Prevention
of Cruelty to Animals, submitted by Samuel J. Milazzo Co., Pittston, Pa.;
CDL: 224446-C)
Hildreth, A.C.; Brown, G.B. (1955) Repellents to Protect Trees and Shrubs from
Damage by Rabbits. By U.S. Agricultural Research Service. Washington, D.C.: U.S.
Dept. of Agriculture. (Technical bulletin no. 1134; available from: Superintendent of
Documents, U.S. Government Printing Office, Washington, DC; also In unpublished
submission received Dec 13, 1973 under 779-29; submitted by Faesy & Besthoff, Inc.,
Edgewater, N.J.; CDL: 022733-B)
Elliott, G.N. (1971) Cotton Seedling Disease Trials—S.J. Valley, 1971.
(Unpublishedstudy received Sep 5, 1974 under 352-312; submitted by E.I. du Pont de
Nemours & Co., Wilmington, Del.; CDL:002466-C)
Bastian, R.A. (1971) Demosan-Arasan—Cotton Trial. (Unpublished study received
Sep 5, 1974 under 352-312; submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL:002466-D)
Paulus, A.O. (1971) Cotton-Rhizoctonia and Pythium—Delta Pine 16. (Unpublished
study including letter dated Jun 7, 1971 from A.O. Paulus to William C. Reische,
received Sep 5, 1974 under 352-312; prepared by Univ. of California—Riverside,
Agricultural Extension Service, Dept. of Plant Pathology, submitted by E.I. du Pont de
Nemours & Co., Wilmington, Del.; CDL:002466-E)
Paulus, A.O. (1972) Cotton Seedling Trial-Rhizoctoma-Pythium, University of
California, Riverside: Variety-Acala SJ—1. (Unpublished study including letter dated
May 16, 1972 from A.O. Paulus to William C. Reische, received Sep 5, 1974 under
352-312; prepared by Univ. of California-Riverside, Agricultural Extension Service,
Dept. of Plant Pathology, submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL:002466-F)
Uniroyal Chemical (1973) Vitavax-Fungicide: Peanut Seed Treatment Test
Summary at 3-6 Oz/100 Pounds of Seed. (Unpublished study received May 2, 1975
129
-------
under 400-81; CDL:098028-A)
00005531 Hsi, D.C.H.; Finkner, R.E. (1969) 1968 Valencia peanut seed treatment. Seed and
Soil Treatment Newsletter 11 (/May 1):56-57. (Also In unpublished submission
received May 2, 1975 under 400-81; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL: 098028-B)
00005532 Hsi, D.C.H.; Finkner, R.E. (1970) Valencia peanut seed treatment. Seed and Soil
Treatment Newsletter 12(/May l):46-47. (Also In unpublished submission received
May 2, 1975 under 400-81; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:098028-C)
00005534 Wells, J.C.; Murphy, C. (1974) Applied Research 1974. (Unpublished study received
May 2, 1975 under 400-81; prepared by North Carolina State Univ., Agricultural
Extension Service, Dept. of Plant Pathology, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL: 098028-E)
00005537 Uniroyal Chemical (1971) Vitavax-Fungicide: Peanut Seed Treatment Test
Summary in Combination with Thiram. (Unpublished study received May 2, 1975
under 400-81; CDL:098028-H)
00005547 Uniroyal, Incorporated (1977) Vitavax: AC-1066-B: Analysis for the Vitavax and
Thiram Content of Vitavax—200 SP. Method dated Jun 15, 1977. (Unpublished
study received Aug 25, 1977 under 400-92; CDL:238082-A)
00005845 Ellis, M.A.; Hepperly, P.R; Paschal, E.H., II; Foor, S.R (19??) Seed treatments.
Pages 189-190, In Fungicide and Nematicide Test, Volume 32. By American
Phytopathological Society. St. Paul, Minn.: APS. (Also In unpublished submission
received Dec 11, 1977 under 400-112; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:238081-B)
00005846 Hepperly, P.R; Sinclair, J.B. (19??) Seed treatments. Pages 190- 191, In Fungicide
and Nematicide Test, Volume 32. By American Phytopathological Society. St. Paul,
Minn.: APS. (Also In unpublished submission received Dec 11, 1977 under 400-
112;CDL: 238081-C)
00005847 Uniroyal Chemical (1976) Soybeans: Vitavax-200 Flowable Fungicide. (Unpublished
study received Dec 11, 1977 under 400-112; CDL: 238081-D)
00005850 Baldwin, C.H., Jr. (1974) Report of Southern Regional Soybean Seed Treatment
Committee-1974. (Unpublished study received Dec 11, 1977 under 400-112;
prepared by Univ. of Missouri, Delta Center, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:238081-G)
00005851 Baldwin, C.H., Jr. (1976) Stand Count Results from the Southern Soybean Disease
Workers Regional Seed Treatment Trials in 1976: Table 1. (Unpublished study
130
-------
00007516
00009534
00009836
00009843
00009844
00009846
00009864
00010336
00011211
00011278
including letter dated Sep 15, 1976 from C.H. Baldwin, Jr. to SSDW Regional
Soybean Seed Treatment Cooperators, received Dec 11, 1977 under 400-112;
prepared by Univ. of Missouri, Delta Center, Cooperative Extension Service,
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:238081-H)
Asgrow Seed Company (1965) (Use of Clorox as a Bean Seed Disinfectant).
(Unpublished study including letter dated Sep 27, 1965 from W.H. Pierce to D.M.
Koons, received Nov 10, 1965 under 5813-1; prepared for Procter and Gamble Co.;
submitted by Clorox Co., Oakland, Calif.; CDL:022523-I)
Edgerton, L. J.; Powell, L.E. (1967) Effects of Some Growth Regulators on Bloom
Date and Cold Hardiness of Apple and Cherry. (Unpublished study received Apr 10,
1967 under 7F0552; prepared by Cornell Univ., Dept. of Pomology, submitted by
United States Rubber Co., Naugatuck, Conn.; CDL:094768-D)
E.I. du Pont de Nemours & Company (1963) Apple-1963: Delaware: Apples,
Sooty Blotch, Gloeodes pomigena . (Unpublished study received Apr 16, 1964
under 352-173; CDL:023213-B)
Hilborn, M. (1952) Mcintosh Single Tree Plots. (Unpublished study received
Apr 16, 1964 under 352-173; submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL:023213-K)
E.I. du Pont de Nemours & Company (1962) Apples—1962: Massachusetts: Du
Pont Test. (Unpublished study received Apr 16, 1964 under 352-173;
CDL:023213-M)
Rich, A. (1952) Orchard Test; Greenhouse Test. (Unpublished study received
Apr 16, 1964 under 352-173; submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL:023213-O)
E.I. du Pont de Nemours & Company (1963) Maneb Residue Data: Apples—1963.
(Unpublished study received Apr 16, 1964 under 352-173; CDL:023213-AL)
E.I. du Pont de Nemours & Company (1963) Apples-1963: Massachusetts: Du Pont
Test. (Unpublished study received Apr 16, 1964 under 352-173; CDL:023213-L)
Johnston, R.L. (1969) Toxicologic Studies with Cycloheximide (ActiDione®).
Summary of studies 210036-C through 210036-L and 210036-N through 210036-AA.
(Unpublished study received Aug 25, 1969 under 1023-EX-27; submitted by Upjohn
Co., Kalamazoo, Mich.; CDL:210036-A)
Glenn, M.W.; Moe, L.D. (1968) Acute (One Hour) Inhalation Exposure of Rats to Dust
Aerosol of Acti-Dione Thiram-Part I. (Unpublished study including letter dated May
15, 1968 from M.W. Glenn and L.D. Moe to R.L. Johnston, received Aug 8, 1969
131
-------
under 1023- 15; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:005453-C)
00011279 Glenn, M.W.; Moe, L.D. (1968) Acute (One Hour) Inhalation Exposure of Rats to Dust
Aerosol of Acti-Dione Thiram—Part n. (Unpublished study including letter dated May
15, 1968 from M.W. Glenn and L.D. Moe to R.L. Johnston, received Aug 8, 1969
under 1023- 15; submittedby Upjohn Co., Kalamazoo, Mch.; CDL:005453-D)
00011504 Klos, E.J.; Rebman, E. (1958) Cherry leaf spot control and physiological effects by new
and standard fungicides. Mchigan Quarterly Bulletin 40(3):646-652. (Also In
unpublished submission received Dec 2, 1976 under 1023-50; submitted by Upjohn
Co., Kalamazoo, Mich.; CDL:095620-H)
00011526 Epstein, A.H. (1970) Fungicidal control of Dothistroma needle blight of Austrian pine.
Plant Disease Reporter 54(8):679-680. (Also In unpublished submission received Dec
30, 1970 under 1109-25; submitted by Cities Service Co., Mnerals Group, Atlanta,
Ga.; CDL:024579-G)
00011557 University of Rhode Island (1958) Comparison of Fungicides for Helminthosporum—
Curvularia, Copper Spot and Dollar Spot Control on Various Bentgrasses.
(Unpublished study received Jan 8, 1960 under 1023-15; prepared by Agricultural
Experiment Station, Dept. of Plant Pathology-Entomology, submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL:024389-C)
00011558 Meyer, W.A.; Britton, M.P.; Gray, L.E.; et al. (1971) Fungicide effects on fungal
ecology in creeping bentgrass turf. Mycopathological & Mycological Applicata 43(3-
4):309-315. (Also In unpublished submission received Sep 26, 1972 under 1023-15;
submitted by Upjohn Co., Kalamazoo, Mch.; CDL:024388-A)
00011559 Richardson, L.T. (19??) The persistence of Thiram in soil and its relationship to the
microbiological balance and damping-off control. Canadian Journal of Botany
32( ):335-346. (Also in unpublished submission received Sep 26, 1972 under 1023-15;
submitted by Upjohn Co., Kalamazoo, Mich.; CDL:024388-B)
00011565 Couch, H.B. (1957) Melting-out of Kentucky bluegrass-Its cause and control. Golf
Course Reporter (/Sep-Oct):5-7. (Also In unpublished submission received Mar 6,
1958 under 1023-10; submitted by Upjohn Co., Kalamazoo, Mch.; CDL:024377-A)
00011608 Goyings, L.S.; Kaczkofsky, B.S. (1968) The Acute Dermal LDI50A of Acti-Dione
Thiram in Rabbits. (Unpublished study including letter dated Sep 18, 1968 from L.S.
Goyings and H.W. Kaczkofsky to R.L. Johnston, received Aug 8, 1969 under 1023-15;
submitted by Upjohn Co., Kalamazoo, Mich.; CDL:005453-B)
132
-------
00012891 Glenn, M.W.; Moe, L.D. (1968) One-Hour Inhalation Exposure of Rats to Dust
Aerosol of Acti-Dione Thiram. (Unpublished study including letter dated Dec 19, 1968
from M.W. Glenn and L.D. Moe to R.L. Johnston, received Aug 8, 1969 under 1023-
15; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:101084-A)
00012892 Glenn, M.W.; Burr, W.M. (1968) Acti-Dione Thiram (Cycloheximide 0.75%): Acute
Oral Toxicity (LDI50A) in the Rat. (Unpublished study including letter dated Apr 17,
1968 from M.W. Glenn and W.M. Burr to R.L. Johnston, received Aug 8, 1969 under
1023-15; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:101084-D)
00018120 Noll, C.J. (1967) Carrot Weed Control 1967. (Unpublished study received Dec 21,
1967 under 1471-35; submitted by Elanco Products Co., Div. of Eli Lilly and Co.,
Indianapolis, Ind.; CDL: 006222-C)
00021610 Mastri, C. (1970) Report to Uniroyal Chemical, Division of Uniroyal, Inc.: Four-Day
Fish Toxicity Study on Three Samples of Vitavax Seed Protectants: IBT No. A8585.
(Unpublished study received Feb 18, 1972 under 400-81; prepared by Industrial BioTest
Laboratories, Inc., submitted by Uniroyal Chemical, Bethany, Conn.; CDL:003261-D)
00021636 Pederson, V.D. (1968) Chemical control of loose smut in barley. Page 4, In Fungicidal
Control of Smut Diseases of Cereals. By J.G. Moseman, comp. Beltsville, Md.: U.S.
Agricultural Research Service, Crops Research Div. (CR 42-68; also In unpublished
submission received Jul 19, 1968 under 400-80; submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:003258-Y)
00021637 Hebert, T.T. (1968) Effect of chemical treatments on the control of loose smut in barley.
Pages 9-11, In Fungicidal Control of Smut Diseases of Cereals. By J.G. Moseman,
comp. Beltsville, Md.: U.S. Agricultural Research Service, Crops Research Div. (CR
4268; also In unpublished submission received Jul 19, 1968 under 400-80; submitted by
Bethany, Conn.; CDL:003258-AB)
00021642 Kline, D.M. (1968) Effectiveness of fungicides in controlling barley loose smut. Page
28,1 Fungicidal Control of Smut Diseases of Cereals. By J.G. Moseman, comp.
Beltsville, Md.: U.S. Agricultural Research Service, Crops Research Div. (CR 42-68;
also In unpublished submission received Jul 19, 1968 under 400- 80; submitted by
Uniroyal Chemical, Bethany, Conn.; CDL: 003258-AK)
00021645 Reddington, K. (1978) Acute Toxicity and Irritation Studies of: Evershield RTU
1000...Vitavax. (Unpublished study received Oct 11, 1978 under KS 78/20; prepared by
Hill Top Testing Services, Inc., submitted by ; CDL:235367-A)
00021648 Uniroyal Chemical (1977) Greenhouse Test-Helminthosporium oryzae . (Unpublished
study received on unknown date under 400-116; CDL:240783-A)
00022063 Britton, M.P. (1970) Turf Diseases. (Unpublished study received Jan 15, 1970 under
1023-50; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:005496-C)
133
-------
00022064
00022065
00022067
00022068
00022548
00022552
00022554
00022557
Shurtleff, M.C. (1970) Disease Control for Lawns and Fine Turf. (Unpublished study
received Jan 15, 1970 under 1023-50; prepared by Iowa State College, submitted by
Upjohn Co., Kalamazoo, Mich.; CDL:005496-D)
Wells, H.D. (1963) Georgia Turfgrass Diseases and Their Control. By Georgia Coastal
Plain Experiment Station, Depts. of Grass Breeding and Plant Pathology. Athens, Ga.:
Univ. of Georgia, Agricultural Experiment Stations. (Circular N.S. 39; also In
unpublished submission received Jan 15, 1970 under 1023-50; submitted by Upjohn
Co., Kalamazoo, Mich.; CDL:005496-E)
Shurtleff, M.C.; Wells, H.D.; Freeman, T.E. (1958) Declare War on turf disease. Parks
& Recreation (/May):230-231. (Incomplete study; also In unpublished submission
received Jan 15, 1970 under 1023-50; submitted by Upjohn Co., Kalamazoo, Mich.;
CDL:005496-L)
University of Nebraska, Extension Service (1970) Control of Lawn Diseases in
Nebraska. Lincoln, Nebr.: UN. (E.C. 58-1818; pp. 10-11 only; also In unpublished
submission received Jan 15, 1970 under 1023-50; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL: 005496-M)
U.S. Environmental Protection Agency (1979) Summary of Reported Pesticide
Incidents Involving Chloroneb: Pesticide Incident Monitoring System Report No. 126.
(U.S. EPA, Office of Pesticide Programs, Benefits and Field Studies Div., Human
Effects Monitoring Branch;
unpublished report.)
Kiesling, R.L. (1968) Chemical control of wheat and barley loose smut. Pages 5-7, In
Fungicidal Control of Smut Diseases of Cereals. By J.G. Moseman, comp. Beltsville,
Md.: U.S.Agricultural Research Service, Crops Research Div. (CR 42-68; also In
unpublished submission received Jul 19, 1968 under 400-80; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:003258-Z)
Hansing, E.D. (1968) A systemic oxathiin fungicide to control loose smuts, covering
smuts, seed rots, and seedling blights of wheat, barley, oats, and sorghum. Pages 11-15,
In Fungicidal Control of Smut Diseases of Cereals. By J.G. Moseman, comp. Beltsville,
Md.: U.S. Agricultural Research Service, Crops Research Div. (CR 42-68; also In
unpublished submission received Jul 19, 1968 under 400-80; submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:003258-AC)
Edgington, L.V. (1968) Chemotherapy of loose smut of barley in Canada. Pages 20-21,
In Fungicidal Control of Smut Diseases of Cereals. By J.G. Moseman, comp. Beltsville,
Md.: U.S.Agricultural Research Service, Crops Research Div. (CR 42-68; also In
unpublished submission received Jul 19, 1968 under 400-80; submitted by Uniroyal
134
-------
Chemical, Bethany, Conn.; CDL:003258-AG)
00022559 Harrison, A.L.; Smith, O.; Simpson, C.E. (1972) Peanut Seed Treatment Tests, 1972.
(Unpublished study received Oct 11, 1972 under 18773-1; prepared by Texas A & M
Univ., Plant Disease Research Station, Prairie View and Tarleton Experiment Stations,
submitted by Turner Sales and Supply, Inc., Tifton, Ga.; CDL: 012032-A)
00023541 Bozarth, G.A.; Tweedy, B.G. (1971) Effect of pesticides on growth and sclerotial
production of Sclerotium rolfsii. Phytopathology 61( ): 1140-1141. (Incomplete study;
also In unpublished submission received Jul 19, 1978 under 201-403; submitted by
Shell Chemical Co., Washington, D.C.; CDL:234469-AH)
00023542 Houseworth, L.D.; Tweedy, B.G. (1973) Effect of Atrazine in combination with Captan
or Thiram upon fungal and bacterial populations in the soil. Plant and Soil 38( ):493-
500. (Also In unpublished submission received Jul 19, 1978 under 201-403; submitted
by Shell Chemical Co., Washington, D.C.; CDL:234469-AK)
00024907 Davis, R.A. (1977) (Efficacy of Herbicides on Soybeans as Weed Control).
(Unpublished study received Jan 8, 1980 under 400-112; prepared in cooperation with
Illinois Crop Improvement Association, submitted by state of Michigan under MI 80/1
for Uniroyal Chemical, Bethany, Conn.; CDL:241559-B)
00024908 Illinois Crop Improvement Association (1977) Effect of Evershield and Vitavax 200
Flowable onSoybean Germinations Read 11/7/77. (Unpublished study received Jan 8,
1980 under 400-112; submitted by state of Michigan under MI 80/1 for Uniroyal
Chemical, Bethany, Conn.; CDL:241559-D)
00024909 Scott, D.H. (1976) Soybean (Glycinemax Amsoy 71) Pre- and Post- emergence
Damping Off Various Seed- and Soil-Borne organisms. (Unpublished study received
Jan 8, 1980 under 400-112; prepared by Purdue Univ., Dept. of Botany and Plant
Pathology, submitted by state of Michigan under MI 80/1 for Uniroyal Chemical,
Bethany, Conn.; CDL:241559-E)
00024910 Uniroyal Chemical (1977) Plot Information. (Unpublished study received Jan 8, 1980
under 400-112; submitted by state of Michigan under MI 80/1 for Uniroyal;
CDL:241559-G)
00024911 Nyvall, R.F. (1978) (Soybean Seed Treatment Tests). (Unpublished study received Jan
8, 1980 under 400-112; prepared in cooperation with Iowa State Univ., submitted by
state of Michigan under MI 80/1 for Uniroyal Chemical, Bethany, Conn.; CDL:241559-
H)
00024912 Uniroyal Chemical (1976) Plot Information. (Unpublished study received Jan 8, 1980
under 400-112; submitted by state of Michigan under MI 80/1 for Uniroyal;
CDL:241559-1)
135
-------
00024913 Ellett, C.W.; Schmitthenner, A.F. (1973) Soybean Seed Treatment-1973. (Unpublished
study received Jan 8, 1980 under 400-112; prepared by Ohio State Univ., Dept. of Plant
Pathology and Ohio Agricultural Research and Development Center, submitted by state
of Michigan under MI 80/1 forUniroyal Chemical, Bethany, Conn.; CDL:241559-J)
00024914 Schmitthenner, A.F. (1977) Evaluation of New Fungicides for Phomopsis Control.
(Unpublished study received Jan 8, 1980 under 400-112; submitted by state of
Michigan under MI 80/1 forUniroyal Chemical, Bethany, Conn.; CDL:241559-K)
00024915 Schmitthenner, A.F. (1978) How Does Fungicide Seed Treatment Affect Yield.
(Unpublished study received Jan 8, 1980 under 400-112; submitted by state of
Michigan under MI 80/1 forUniroyal Chemical, Bethany, Conn.; CDL:241559-L)
00024917 Uniroyal Chemical (1979) Summary: Vitavax. (Unpublished study received Oct 18,
1979 under 400-112; prepared in cooperation with Morse Laboratories, Inc.;
CDL:241184-A)
00024918 McLeod, H.A.; McCully, K.A. (1969) Head space gas procedure for screening food
samples for Dithiocarbamate pesticide residues. Journal of the Association of Official
Analytical Chemists 52(6): 1226-1230. (Also in unpublished submission received Oct
18, 1979 under 400-112; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:241184-B)
00024919 Hulsey, C.J.; Hulsey, J.; Parker, R.C. (1979) Comparison of Germinations of Soybean
Seed Treated vs. Untreated with Vitavax-200 Flowable Fungicide. (Unpublished study
including published data, received Oct 18, 1979 under 400-112; prepared in
cooperation with Hulsey Seed Laboratory, Inc., submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:241184-C)
00025471 Reed, H.E.; Chambers, A.Y.; Richard, G.; et al. (1969) Efficacy in Barley.
(Unpublished study including published data, received Jan 12, 1970 under 0F0939;
prepared in cooperation with Univ. of Tennessee, Agricultural Experiment Station,
Dept. of Agricultural Biology and others, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:091604-J)
00025475 Roberts, T.G. (1969) Efficacy Data for Vitavax on Peanuts. (Unpublished study
received Jan 12, 1970 under 0F0939; submitted by Uniroyal Chemical, Bethany, Conn.;
CDL:091604-N)
00025482 Uniroyal Chemical (1974) Toxicity of Vitavax to Fish and Wildlife. (Unpublished study
received Jun 17, 1974 under 5F1525; CDL: 094043-G)
00025483 Uniroyal, Incorporated (1974) Summary of Corn and Rice Residue Data. (Unpublished
study received Jun 17, 1974 under 5F1525; prepared in cooperation with Morse
Laboratories, Inc. and State Univ. College of New York-Oswego, Lake Ontario
Environmental Laboratory; CDL:094043-H)
136
-------
00025486
00028165
00028640
00029050
00029370
00030603
00030715
00032175
00032235
Uniroyal Chemical (1972) Vitavax Handling Toxicity Studies. (Unpublished study
received Jun 17, 1974 under 5F1525; CDL: 094043-J)
Noll, C.J. (1968) Chemical Weeding of Carrots: Research Report CF2597.
(Unpublished study received Jul 24, 1968 under 8F0649; prepared by Pennsylvania
State Univ., Experiment Station, Dept. of Horticulture, submitted by Ciba
Agrochemical Co., Summit, N.J.; CDL:096517-N)
Jackson, N. (1979) Efficacy of Kromad on Various Organisms. (Unpublished study
received Jan 24, 1980 under 372-24; prepared in cooperation with Univ. of Rhode
Island, submitted by Mallinckrodt, Inc., St. Louis, Mo.; CDL:241943-A)
Haskett, W.C.; VandeStreek, E.; Leben, C.; et al. (1962) Stem Treatments with Botran
for Botrytis Control in Greenhouse Tomatoes. (Unpublished study received Jun 1, 1963
under PP0375; prepared in cooperation with Ohio Agricultural Research and
Development Center, Agricultural Experiment Station, Dept. of Bo- tany and Plant
Pathology and others, submitted by Upjohn Co., Kalamazoo, Mich.; CDL:090404-R)
O.M. Scott & Sons Company (1964) Summary of Research Results with Granular
Diphenamid (N-N-Dimethyl-2,2-diphenylacetamide) Formulations for the Control of
Poa annua, Kentucky Bluegrass, Red Fescue, Bentgrass, Coarse Fescue, Redtop,
Crabgrass, Foxtail Barley, Chickweeds, Marsh Parsley and Other Weeds in Dichondra
Lawns. (Unpublished study received Nov 19, 1964 under 538-67; CDL:023113-A)
Ashworth, L.J., Jr.; Langley, B.C.; Thames, W.H., Jr. (1961) Comparative
pathogenicity of Sclerotium rolfsii and Rhizoctonia solani to Spanish peanut.
Phytopathology 51(/Sep):600-605. (Also In unpublished submission received Sep 13,
1976 under 400-129; submitted by Uniroyal Chemical, Bethany, Conn.; CDL: 225604-
F)
Simone,; Jackson,; Couch,; et al. (1978) Results from Tersan 1991 & Daconil Alone
& in Combination on Turfgrass. (Unpublished study received Feb 29, 1980 under 352-
357; prepared in cooperation with Univ. of Illinois and others, submitted by E.I. du Pont
de Nemours & Co.,
Wilmington, Del.; CDL:241974-A)
Uniroyal Chemical (1979) Vitavax (R) Fungicide. : Uniroyal. (Technical data sheet;
Also In unpublished submission received Jun 3, 1980 under OK 80/9; submitted by
Oklahoma, Dept. of Agriculture, Oklahoma City, Okla.; CDL:242612-A)
Harrod, J.; Nesmith,; Jackson,; et al. (1980) Results from Tersan 1991 & Tersan LSR
Alone & in Combination on Turfgrass. (Unpublished study received Feb 29, 1980 under
352-357; prepared in cooperation with Kansas State Univ. and others, submitted by E.I.
du Pont de Nemours & Co., Wilmington, Del.; CDL:241973-A)
137
-------
00032270
00032880
00034068
00034238
00034300
00034301
00034302
00034303
00034305
00034307
Roussel, J.H.; Tire, W.W.; Schmitt, D.P.; et al. (1979) Efficacy of Fungicides on
Soybean Seeds. (Unpublished study received Mar 21, 1980 under LA 80/5; prepared in
cooperation with North Carolina State Univ., Dept. of Plant Pathology and others,
submitted by state of Louisiana for Olin Corp., Stamford, Conn.; CDL:242086-A)
Apple, J.; Lilly, J.H. (1953) Efficacy in Oats, Lima Beans and Corn. (Unpublished study
received Aug 9, 1954 under 876-7; prepared by Univ. of Wisconsin, Agricultural
Experiment Station, Dept. of Entomology in cooperation with Iowa State Univ. of
Science and Technology, Agricultural Experiment Station, Dept. of Entomology,
submitted by Velsicol Chemical Corp., Chicago, 111.; CDL:000375-A)
Rowell, J.O.; Dominick, C.B.; Bissell, T.L. (1965) Efficacy Data for Insecticides on
Corn. (Unpublished study including published data, received May 24, 1965 under 100-
460; prepared by Virginia Polytechnic Institute, Agricultural Extension Service in
cooperation with Univ.of Maryland, Dept. of Entomology, submitted by Ciba-Geigy
Corp., Greensboro, N.C.; CDL:000380-J)
University of California-Davis, Division of Entomology (1950) Report to Julius
Hyman & Company. (Unpublished study received Jan 26, 1952 under unknown admin,
no.; submitted by Shell Chemical Co., Washington, D.C.; CDL:000740-M)
Hillborn, M.T.; Hamilton, J.M.; Szkolnik, M.; et al. (1956) Vancide Field Test Report.
(Unpublished study received Jan 26, 1956 under 279-1017; prepared in cooperation
with Univ. of Maine, Agricultural Experiment Station and others, submitted by FMC
Corp., Philadelphia, Pa.; CDL:002277-A)
FMC Corporation (1956) Toxicological Data. (Unpublished study received Jan 26,
1956 under 279-1017; CDL:002277-B)
R.T. Vanderbilt Company, Incorporated (1956) Toxicology~Vancide. (Unpublished
study received Jan 26, 1956 under 279-1017; submitted by FMC Corp., Philadelphia,
Pa.; CDL:002277-C)
Food Research Laboratories, Incorporated (1954) Acute Oral Toxicity of Vancide F-
995: Laboratory No. 68712. (Unpublished study received Jan 26, 1956 under 279-1017;
submitted by FMC Corp., Philadelphia, Pa.; CDL:002277-D)
FMC Corporation (1955) Determination of Vancide Residues on Apples. (Unpublished
study received Jan 26, 1956 under 279-1017; CDL: 002277-G)
FMC Corporation (1956) Determination of Tetramethyl thiuram disulfide Residues in
Apple Samples. Undated method. (Unpublished study received Jan 26, 1956 under 279-
1017; CDL:002277-I)
138
-------
00034309
00034381
00034651
00034652
00035277
00038301
00038802
00038803
00038804
00039235
00039974
FMC Corporation (1955) Residue Data for Vancide on Apples. (Unpublished study
received Jan 26, 1956 under 279-1017; CDL: 002277-K)
Dobie, N.D. (1961) Pear. (Unpublished study received Apr 6, 1962 under 279-1017;
prepared in cooperation with Oregon State Univ., submitted by FMC Corp.,
Philadelphia, Pa.; CDL:002278-A)
Freeman, T.E.; Mullin, R.S. (1962) Turfgrass Disease Control Guide. Gainesville, Fla.;
Univ. of Florida, Agricultural Extension Service. (Circular 221; also In unpublished
submission received Jan 15, 1970 under 1023-50; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL:005496-F)
Couch, H.B. (1957) Melting-out of Kentucky bluegrass~its cause and control. Golf
Course Reporter 25(7):5-7. (Also In unpublished submission received Jan 15, 1970
under 1023-50; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:005496-J)
Julis, A. J. (1980) The Effect of DPX-4189 on Microorganisms and Microbial
Populations of Soils: AMR-13-80. (Unpublished study received Jun 16, 1980 under
352-105; submitted by E.I. du Pont de Nemours & Co., Wilmington, Del.;
CDL:099462-X)
Uniroyal Chemical (1974) Residues in PPM. (Unpublished study received May 13,
1980 under CO 80/6; submitted by state of Colorado for Uniroyal; CDL:241468-B)
Barry, J. A. (1977) Darcom Security Information Bulletin. (Darcom SIB # 3;
unpublished study received Jan 15, 1980 under 1001-59; submitted by W.A. Cleary
Corp., Somerset, N.J.; CDL:242894-A)
Jerome, E.A. (1977) Airport Safety Bulletin: The Deerstrike Hazard. Arlington, Va.:
Flight Safety Foundation, Inc. (Also In unpublished submission received Jan 15, 1980
under 1001-59; submitted by W.A. Cleary Corp., Somerset, N.J.; CDL:242894-B)
Gwinner, G.M. (1979) Controlling deer in plantations. Christmas Trees (/Jan): 18,20-
23. (Also In unpublished submission received Jan 15, 1980 under 1001-59; submitted
by W.A. Cleary Corp., Somerset, N.J.; CDL:242894-C)
Field, G.; Miller, P.M.; Moore, R.C.; et al. (1970) 1970 Apple Spray Guide for
Connecticut and Rhode Island. By Univ. of Connecticut and Univ. of Rhode Island,
Cooperative Extension Service. N.P. (Incomplete; also In unpublished submission
received Sep 29, 1970 under 279-2032; submitted by FMC Corp., Philadelphia, Pa.;
CDL: 00243 3-A)
Hildreth, A.C.; Brown, G.B. (1955) Protecting Trees and Shrubs from Rabbit Damage.
By U.S.Agricultural Research Service, Horticultural Crops Research Branch.
139
-------
Washington, D.C.: U.S. Government Printing Office. (Leaflet no. 396; available from:
Superintendent of Documents, USGPO, Washington, DC; 1955-0-350201, published
study; CDL:022733-A)
00041997 Ryker, T.C. (1970) Letter sent to C.C. Compton dated Jun 26, 1970 (Thiram residues in
onions). (Unpublished study received Nov 1, 1970 under 1E1123; prepared by E.I. du
Pont de Nemours & Co., submitted by Interregional Research Project No. 4, New
Brunswick, N.J.; CDL:090898-A)
00043387 Ackerson, C.W.; Mussehl, F.E. (1948) Toxicity of Treated Seed Corn in Rations for
Chicks. (Journal series paper no. 666; unpublished study received Jun 22, 1970 under
unknown admin, no.; prepared by Univ. of Nebraska, Depts. of Biochemistry and
Nutrition and Poultry Husbandry, submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:107818-F)
00043389 Meade, R.J.; Warner, D R.; Lambert, W.V.; et al. (1954) The Effect of Seed
Disinfectants, Orthocide and Arasan, upon the Performance of Growing-Fattening
Swine. Swine progress rept. # 328. (Unpublished study received Jun 22, 1970 under
unknown admin, no.; prepared by Univ. of Nebraska, Agricultural Experiment Station,
submitted by Chevron Chemical Co., Richmond, Calif.; CDL: 107818-H)
00045160 E.I. du Pont de Nemours & Company, Incorporated (1955) Name, Chemical Identity
and Composition: Thiram. (Unpublished study received Aug 20, 1957 under PP0144;
CDL:092424-A)
00045161 E.I. du Pont de Nemours & Company, Incorporated (1954) Summary of Toxicity
Information on Thiram. (Unpublished study received Aug 4, 1957 under PP0144;
CDL:092424-B)
00045162 E.I. du Pont de Nemours & Company, Incorporated (1954) Summary of Feeding
Studies with Thiram at the University of Rochester. (Unpublished study received Aug 4,
1957 under PP0144; prepared in cooperation with Univ. of Rochester and U.S. Food
and Drug Administration, Div. of Pharmacology; CDL:092424-C)
00045163 E.I. du Pont de Nemours & Company, Incorporated (1957) Reports of Investigations
with Respect to Safety of Thiram. (Unpublished study received Aug 20, 1957 under
PP0144; CDL:092424-D)
00045164 Horsfall, J.G.; Darby, J.F.; Cox, R.S.; et al. (1957) Additional Data in Support of
Petition: Summary. (Unpublished study inincluding published data, received Aug 20,
1957 under PP0144; prepared in cooperation with Univ. of Connecticut, Agricultural
Experiment Station and others, submitted by E.I. du Pont de Nemours & Co., Inc.,
Wilmington, Del.; CDL:092424-E)
00045165 E.I. du Pont de Nemours & Company, Incorporated (1957) Results of Tests on the
Amount of Residue Remaining on Food Crops: Thiram. (Unpublished study received
140
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Aug 4, 1957 under PP0144; CDL:092424-F)
00045617 Interregional Research Project Number 4 (1971) Composition of ArasanA(R)I 50-Red
Thiram Seed Protectant. (Unpublished study received on unknown date under IE 1123;
CDL:093433-A)
00046435 Shirasu, Y.; Moriya, M.; Kato, K.; et al. (1976) Mutagenicity screening of pesticides in
the microbial system. Mutation Research 40( ): 19-30. (Also in unpublished submission
received May 28, 1980 under 1023-57; submitted by Upjohn Co., Kalamazoo, Mich.;
CDL:242524-A)
00047271 R.T. Vanderbilt Company, Incorporated (1967) VancideA(R)I TM-W: 95% Thiram
Wettable Powder. (Unpublished study received Jun 13, 1967 under 1965-53;
CDL:105274-A)
00047580 Halmos, S.; Stover, R.H. (1967) Effectiveness of Fungicides against Spore Germination
of Fusarium roseum and Pyricularia grisen . (Unpublished study including letter dated
Jul 8, 1968 from W.T. van Diepen to B.B. Hodgden, received Sep 10, 1968 under
9F0758; prepared by United Fruit Co., submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, DEL; CDL:093070-A)
00047581 E.I. du Pont de Nemours & Company, Incorporated (1968) Residue Data Thiram—
Bananas.
(Unpublished study received Sep 10, 1968 under 9F0758; CDL:093070-B)
00051232 Lemin, A.J. (1977) Letter sent to Federal Register Section, Technical Services Division
(WH-569), OPP, EPA dated Sep 27, 1977: OPP-30018; Comments and information
impacting on use classification of Cycloheximide-containing products. Summary of
studies 231998-B through 231998-F and 231998-H through 231998-AB. (Unpublished
study received Sep 29, 1977 under 1023-10; submitted by Upjohn Co., Kalamazoo,
Mich.; CDL:231998-A)
00051692 Zummo, N; Plakidas, A.G. (1958) Brown patch of St. Augustine grass. Plant Disease
Reporter 42(10): 1141-1147. (Also in unpublished submission received Feb 25, 1959
under 1258-524; submitted by Olin Corp., Stamford, Conn.; CDL:005753-A)
00052133 Parker, R.C.; Hansing, E.D.; Hanson, C.L.; et al. (1978) Oats. (Unpublished study
including published data, received May 13, 1980 under CO 80/6; prepared in
cooperation with Univ. of Wisconsin, Dept. of Plant Pathology and Kansas State Univ.,
Dept. of Plant Pathology, submitted by state of Colorado for Uniroyal Chemical,
Bethany, Conn.; CDL:242468-A)
00053189 Alcor Products (1972) Data Relating to Safety of Repel Animal Repellent.
(Unpublished study received Jun 24, 1974 under 20215- 1; CDL:051047-A)
00053191 Marsh, M.L. (1972) Toxicological and Safe Handling Information: Thiuram M.
141
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00053968
00055542
00055579
00055580
00055581
00055590
00055591
00056355
00057404
00057406
(Unpublished study received Jun 24, 1974 under 20215-1; prepared by E.I. du Pont de
Nemours & Co., submitted by Alcor Products, Carlsbad, Calif.; CDL:051047-C)
E.I. du Pont de Nemours & Company (1960) Thiram. (Unpublished study received Jun
24, 1955 under unknown admin, no.; prepared in cooperation with California, Dept. of
Agriculture; CDL: 105275-A)
Reddington, K. (1978) Acute Toxicity and Irritation Studies of: Evershield RTU 1000--
10% Thiram; Evershield RTU 1050—10% Thiram t 5% Vitavax; Evershield RTU
1010-10%) Thiram + 10%> Vitavax. (Unpublished study received Oct 20, 1980 under
ND 80/20; submitted by North Dakota, Dept. of Agriculture, Bismarck, N.Dak.;
CDL:243739-A)
Glenn, M.W.; Burr, W.M. (1968) Acti-dione Thiram (Cycloheximide 0.75%) Acute
Oral Toxicity (LDI50A) in the Rat. (Unpublished study including letter dated Apr 17,
1968 from M.W. Glenn and W.M. Burr to R.L. Johnston, received Sep 29, 1977 under
1023-10; submitted by Upjohn Co., Kalamazoo, Mich.; CDL:231998-P)
Goyings, L.S.; Kaczkofsky, H.W. (1968) The Acute Dermal LDI50A of Acti-dione
Thiram in Rabbits. (Unpublished study including letter dated Sep 18, 1968 from L.S.
Goyings and H.W. Kaczkofsky to R.L. Johnston, received Sep 29, 1977 under 1023-10;
submitted by Upjohn Co., Kalamazoo, Mich.; CDL:231998-Q)
Upjohn Company (1968) One-Hour Inhalation Exposure of Rats to Dust Aerosol of
Actidione Thiram. (Compilation; unpublished study received Sep 29, 1977 under 1023-
10; CDL:231998-R)
Upjohn Company (1959) Skin Irritation in Rabbits. (Compilation; unpublished study
received Sep 29, 1977 under 1023-10; CDL: 231998-AA)
Upjohn Company (1959) Eye Irritation in Rabbits. (Compilation; unpublished study
received Sep 29, 1977 under 1023-10; CDL: 231998-AB)
Baer, R.L.; Rosenthal, S.A. (1954) The germicidal action on human skin of soap
containing Tetramethylthiuram disulfide. Journal of Investigative Dermatology 23:193-
211. (Also In unpublished submission received on unknown date under unknown
admin, no.; submitted by; CDL:223282-A)
Amy, D.C. (1971) Letter sent to Otto E. Wenger dated Jul 28, 1971 Vitavax-Thiram
used against oat smut. (Unpublished study received Sep 27, 1972 under 3F1318;
prepared by Univ. of Wisconsin, Dept. of Plant Pathology, submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:093547-G)
Barron, J.E. (1972) Letter sent to R.E. Grahame dated Jun 5, 1972: Shelf life of Vitavax
plus Thiram (Vitavax-200). (Unpublished study received Sep 27, 1972 under 3F1318;
142
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submitted by Uniroyal Chemical, Bethany, Conn.; CDL:093547-L)
00057420 Hollingsworth, R.B. (1970) Letter sent to Bill Atchison dated Dec 29, 1970 Efficacy
studies of Vitavax and Thiram on corn. (Unpublished study received Dec 23, 1972
under 3F1318; prepared by Cargill, Inc., submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:092253-L)
00057421 Laible, C.A. (1972) Letter sent to Keith M. McReynolds dated Jan 27, 1972 Field
performance data on corn. (Unpublished study received Dec 23, 1972 under 3F1318;
prepared by Funk Bros. Seed Co., submitted by Uniroyal Chemical, Bethany, Conn.;
CDL: 092253-0)
00057424 Fulton, N.D. (1971) Letter sent to Sharon Mclntire dated Sep 10, 1971 Data from
Arkansas cottonseed regional fungicide test. (Unpublished study received Apr 12, 1972
under 400-80; prepared by Univ. of Arkansas, Div. of Agriculture, Agricultural
Experiment Station, Dept. of Plant Pathology, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:023352-G)
00057425 Templeton, G.E. (1972) Letter sent to Sheron Mclntire dated Jun 28, 1972 Results of
rice seed treatment trials in Arkansas during 1972. (Unpublished study received Dec 20,
1977 under 400-116; prepared by Univ. of Arkansas, Div. of Agriculture, Agricultural
Experiment Station, Dept. of Plant Pathology, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:232528-D)
00057426 Rush, M.C. (1975) Letter sent to Sheron Mclntire dated Jun 30, 1975 Efficacy of
Vitavax and Vitavax-Thiram. (Unpublished study received Dec 20, 1977 under 400-
116; prepared by
Louisiana State Univ., Center for Agricultural Sciences and Rural Development,
Agricultural Experiment Station, Dept. of Plant Pathology, submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:232528-F)
00057427 Rush, M.C. (1975) Letter sent to Sheron Mclntire dated Aug 20, 1975 Efficacy data on
rice. (Unpublished study received Dec 20, 1977 under 400-116; prepared by Louisiana
State Univ., Center for Agricultural Sciences and Rural Development, Agricultural
Experiment Station, Dept. of Plant Pathology, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:232528-G)
00057428 Dupre, R. (1978) Letter sent to Reto Engler dated Jun 19, 1978 Dermal LD-50 of
Vitavax-200 flowable fungicide. (Unpublished study received Jul 14, 1978 under 400-
112; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:235042-H)
00057429 Uniroyal Chemical (1978) Letters Requesting Registration of Vitavax 200 Flowable
Fungicide for Treatment of Soybean Seed. (Compilation; unpublished study received
Nov 14, 1978 under 400- 112; CDL:235936-A)
00057430 Nyvall, RF. (1977) Letter sent to John MacFarlane dated Nov 29, 1977 Results from
143
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field study with soybeans. (Unpublished study received Nov 14, 1978 under 400-112;
prepared by Iowa State Univ. of Science and Technology, Cooperative Extension
Service, Dept. of Botany and Plant Pathology, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:235936-G)
00057431 Nyvall, R.F. (1976) Letter sent to John J. MacFarlane dated Oct 28, 1976 Results from
field study with soybeans. (Unpublished study received Nov 14, 1978 under 400-112;
prepared by Iowa State Univ. of Science and Technology, Cooperative Extension
Service, Dept. of Botany and Plant Pathology, submitted by Uniroyal Chemical,
Bethany, Conn.; CDL:235936-H)
00057432 MacNab, S. (1978) Letter sent to Roy C. Parker dated Mar 2, 1978 Results from warm
germination and cold tests. (Unpublished study received Nov 14, 1978 under 400-112;
prepared by Indiana Crop Improvement Association, Inc., submitted by Uniroyal
Chemical, Bethany, Conn.; CDL:235936-U)
00057435 Barron, J.E. (1969) Letter sent to B. von Schmeling dated Dec 19, 1969: Composition
of Vitavax seed protectant with Thiram. (Unpublished study received Jan 12, 1970
under 0F0939; submitted by Uniroyal Chemical, Bethany, Conn.; CDL:093245-P)
00057461 Geise, T.E., Jr. (1973) Letter sent to T.J. Schmidt dated May 3, 1973: Uni-1088 and
Uni-1090 assay stability results for federal labeling procedures. (Unpublished study
received May 16, 1973 under 400-107; submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:003284-A)
00061502 Allers, W.D. (1944) Letter sent to the Director, AIHL dated Nov 20, 1944 (Various
tests with p-Nitrophenol). (U.S. Army Service Forces, Army Industrial Hygiene
Laboratory; unpublished study; CDL:230416-Q)
00062720 Johnson, R.C. (1957) Dansal Q Industrial Bacteriostat. (Unpublished study received
Apr 15, 1957 under 352-226; submitted by E.I. du Pont de Nemours & Co.,
Wilmington, Del.; CDL:229458-A)
00062797 Kreuzmann, J. (1980) Acute Oral and Acute Dermal Toxicity, Primary Dermal
Irritation, D.O.T.Corrosivity, and Acute Eye Irritation Potentials of Cargill Flo Pro T
Thiram 29.52% by Weight: Ref. 80-802-21. (Unpublished study received Dec 3, 1980
under 1352-32; prepared by Hill Top Research, Inc., submitted by Cargill, Inc.,
Minneapolis, Minn.; CDL:243873-A)
00062798 Minton, E. (1980) Cottonseed Seedling Survival, Stoneville 213. (U.S. Dept. of
Agriculture; unpublished study; CDL:243873-B)
144
-------
00062799
Cargill, Incorporated (1979) Efficacy of Various Chemicals on Soybeans. (Compilation;
unpublished study received Dec 3, 1980 under 1352-32; CDL:243873-C)
00063865 Cargill, Incorporated (1980) RTU-1010 Small Grain Seed Protectant: Confidential
Statement of Formulation. (Unpublished study received Nov 18, 1980 under KS 80/19;
submitted by Kansas, State Board of Agriculture, Control Div. for Cargill;
CDL:243817-A)
00063866 Cargill, Incorporated (1979) Control of Loose Smut on Barley and Wheat. (Reports by
various sources; unpublished study, including letters dated Sep 24, 1980 from H.A.
Lamey to William Johnson and Oct 2, 1980 from W.G. Willis to Chuck Edwards,
received Nov 18, 1980 under KS 80/19; submitted by Kansas, State Board of
Agriculture, Control Div. for Cargill;
CDL:243817-B)
00064247 E.I. du Pont de Nemours & Company (1965) Efficacy Studies on Soybeans.
(Unpublished study received Mar 8, 1965; Mar 23, 1967 under 352-310;
CDL:023285-D)
00064372 W.A. Cleary Corporation (1969) Efficacy of Some Turfgrass Fungicides. (Compilation;
unpublished study received Jan 2, 1970; Jan 20, 1970 under 1001-46; CDL:228390-A)
00064373 Stoker Company (1967) Butyric Acid. (Compilation; unpublished study received Dec 9,
1969; Dec 11, 1969 under unknown admin, no.; CDL:228419-A)
00065002 Twombly, R.A. (1959) Letter sent to George Swank dated Oct 16, 1959 Report on
GAB-5. (Unpublished study received Jan 8, 1960 under 1023-15; prepared by Old Oaks
Country Club, submitted by Upjohn Co., Kalamazoo, Mich.; CDL:024389-B)
00065172 Scientific Chemicals, Incorporated (1968) Socci #5630-PB. (Unpublished study
received Jul 26, 1968; Jun 10, 1968; Jan 22, 1964 under 2829-23; submitted by Thiokol
Corp., Ventron Div., Danvers, Mass.; CDL:025515-B)
00065321 Asgrow Research Center (1963) Cold Test Studies of Cucurbit Seed Treatments.
(Unpublished study received Sep 25, 1963 under 352-297; submitted by E.I. du Pont de
Nemours & Co., Wilmington, Del.; CDL:229586-A)
00065725 E.I. du Pont de Nemours & Company (1977) Manufacturing Process, Purity of Starting
and Intermediate Materials, and Composition of Thiram Technical. (Unpublished study
received Feb 7, 1977 under 352-114; CDL:229265-A)
00065726 E.I. du Pont de Nemours & Company (1971) Methods for Thiram. Includes methods
dated Jun 24, 1971 and Aug 16, 1971. (Compilation; unpublished study received Feb 7,
1977 under 352-114; CDL: 229265-B)
00065727 E.I. du Pont de Nemours and Company (1972) Thiram Technical Data Sheet.
(Unpublished study received Feb 7, 1977 under 352-114; CDL:229265-D)
145
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00067336 Karrh, B.W. (1976) Letter sent to John E. Moss dated Oct 4, 1976 Results of analyses
of du Pont pesticides for dimethylnitrosamines (DMN). (Unpublished study received
Dec 8, 1976 under 352-378; submitted by E.I. du Pont de Nemours & Co., Wilmington,
Del.; CDL:230783-A)
00067666 White, H. (1976) Kalo Formulation Q1360876: Acute Oral Toxicity in Rats:
Study No. 974-004-101-0976. (Unpublished study received on unknown date under
15382-14; submitted by Kalo Laboratories, Inc., Kansas City, Mo.; CDL:235652-B)
00067667 White, H. (1976) Kalo Formulation Q1360876: Acute Oral Toxicity in Mice: Study
No.974-004-302-0976. (Unpublished study received on unknown date under 15382-14;
submitted by Kalo Industries, Inc., Kansas City, Mo.; CDL:235652-C)
00067668 White, H. (1976) Acute Dermal Toxicity in Mice: Kalo Formulation Q1360876, Kalo
Formulation Q1400976: Study Nos. 124-004-3051076; 974-004-304-1076.
(Unpublished study received on unknown date under 15382-14; submitted by Kalo
Industries, Inc., Kansas City, Mo.; CDL:235652-D)
00067669 White, H. (1976) Kalo Formulation Q1360876: Primary Skin Irritation Study in
Rabbits: Study No. 124-009-404-1076. (Unpublished study received on unknown date
under 15382-14; submitted by Kalo Industries, Inc., Kansas City, Mo.; CDL:235652-E)
00067670 White, H. (1976) Kalo Formulation Q1360876: Primary Eye Irritation Study in Rabbits:
Study No. 124-008-406-1076. (Unpublished study received on unknown date under
15382-14; submitted by Kalo Industries, Inc., Kansas City, Mo.; CDL:235652-F)
00067671 Dean, W.P. (1976) Acute Inhalation Toxicity in Albino Rats: IRDC Study No. 380-005.
(Unpublished study received on unknown date under 15382-14; prepared by
International Research and Development Corp., submitted by Kalo Industries, Inc.,
Kansas City, Mo.; CDL:235652-G)
00068602 FMC Corporation (1956) Description of Interconversion of Chemical Compounds in
Niacide M. (Unpublished study received Jan 14, 1957 under 279-1164; CDL:229821-
B)
00069090 Baer, R.L.; Ramsey, D.L.; Biondi, E. (1973) The most common contact allergens.
Archives of Dermatology 108(l):75-78. (Also In unpublished submission received Apr
25, 1977 under 4816465; submitted by Fairfield American Corp., Medina, N.Y.; CDL:
229968-C)
00070694 Hoppe, P.E. (1957) A comparison of Capton and Arasan for corn seed treatment. Plant
Disease Reporter 41(10):857-859. (Also In unpublished submission received Feb 1,
1960 under 476-1423; submitted by Stauffer Chemical Co., Richmond Calif.; CDL:
231058-A)
146
-------
00070695 Hoppe, P.E. (1958) Correlation between laboratory cold tests and field stands of corn.
Plant Disease Reporter 42(3):367-372. (Also In unpublished submission received Feb 1,
1960 under 4761423; submitted by Stauffer Chemical Co., Richmond, Calif.;
CDL:231058-B)
00070820 Michaelson, J.B. (1975) Oral Toxicity (LDI50A Determination): Laboratory No. 10655.
(Unpublished study received Jul 30, 1975 under 20215-1; prepared by Applied
Biological Sciences Laboratory, submitted by Alcor Products, Carlsbad, Calif.;
CDL:221979-A)
00070821 Michaelson, J.B. (1975) Acute Dermal Toxicity: Laboratory # 10655. (Unpublished
study received Jul 30, 1975 under 20215-1; prepared by Applied Biological Sciences
Laboratory, submitted by Alcor Products, Carlsbad, Calif.; CDL:221979-B)
00070822 Michaelson, J.B. (1975) Draize Eye Test: Laboratory No. 10655. (Unpublished study
received Jul 30, 1975 under 20215-1; prepared by Applied Biological Sciences
Laboratory, Inc., submitted by Alcor Products, Carlsbad, Calif.; CDL:221979-C)
00070823 Michaelson, J.B. (1975) Primary Skin Irritation: Laboratory No. 10655. (Unpublished
study received Jul 30, 1975 under 20215-1; prepared by Applied Biological Sciences
Laboratory, Inc., submitted by Alcor Products, Carlsbad, Calif.; CDL: 221979-D)
00072179 Rohm and Haas Company (1979) Abstracts of Mutagenic Studies. Summary of studies
238640-G, 238640-H, 238640-R, and 238640-S. (Unpublished study received Jun 20,
1979 under 707-88; CDL: 238640-F)
00072192 Paik, S.G.; Lee, S.Y. (1977) Genetic effects of pesticides in the mammalian cells: I.
Induction of micronucleus. Korean Journal of Zoology 20(1): 19-28. (Also In
unpublished submission received Jun 20, 1979 under 707-88; submitted by Rohm &
Haas Co., Philadelphia, Pa.; CDL:238640-S)
00072813 Miller, P.A.; Border, E.G.; MacDonald, A.G.; et al. (1955) Study on Turfgrass Disease
Control. (Unpublished study received Feb 1, 1957 under 2059-7; prepared by Univ. of
California—Los Angeles and others, submitted by Vaughan's Seed Co., Bound Brook,
N.J.; CDL:006767-A)
00073039 Barron, J.E. (1974) Letter sent to J.T. Schmidt dated Jun 17, 1974: Composition of
Vitavax®-200 Fungicide. (Unpublished study received Jun 10, 1975 under 400-92;
submitted by Uniroyal Chemical, Bethany, Conn.; CDL:097591-A)
00075879 E.I. du Pont de Nemours & Company (1956) Reports of Investigations Made with
Respect to Safety of Thiram. (Compilation; unpublished study received on unknown
date under PP0052; CDL: 090050-A)
00075880 E.I. du Pont de Nemours & Company (1955) Results of Tests on the Amount of
Residue Remaining on Apples: Thiram. (Unpublished study received Nov 5, 1955
147
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under PP0052; CDL:090050-B)
00075892 Niagara Chemical (1954) Residue Study on Apples Using Dithiocarbamate and
Benzothiazyl Disulfide. Includes undated test method 82A. (Compilation; unpublished
study received Mar 17, 1981 under PP0012; CDL:090011-A)
00075893 Niagara Chemical (1955) Names, Chemical Identity and Composition of Pesticide
Chemicals: Vancide. (Unpublished study received Mar 17, 1955 under PP0012;
CDL:090011-D)
00075894 Hodge, H.C. (1955) Letter sent to O.H. Johnson dated Aug 27, 1955 Pilot feeding
studies of thiram given to dogs. (Unpublished study received on unknown date under
PP0012; prepared by Univ. of Rochester, Strong Memorial Hospital, submitted by
Niagara Chemical, Div. of FMC Corp., Los Fresnos, Tex.; CDL:090011-E)
00075897 Niagara Chemical (19??) Thiram Residues on Food Crops in Presence of
Dithiocarbamates. Undated method. (Unpublished study received Mar 17, 1955 under
PP0012; CDL:090011-H)
00075898 Hodge, H.C.; Maynard, E.A.; Downs, W.; et al. (1955) Pilot Feeding Tests of Thiram in
Dogs. (Unpublished study received on unknown date under PP0012; prepared by Univ.
of Rochester, Div. of Pharmacology and Toxicology, submitted by Niagara Chemical,
Div. of FMC Corp., Los Fresnos, Tex.; CDL:090011-I)
00076048 California Spray-Chemical Corporation (1960) Efficacy of Phaltan on Cotton.
(Compilation;
unpublished study received Jan 15, 1962 under 239-1776; submitted by Chevron
Chemical Co., Richmond, Calif.; CDL:231196-A)
00077080 Ralston Purina Company (1980) Primary Eye Irritation-Method, Summary, Raw Data
Attached: RT Lab No. 807772. (Unpublished study received Mar 18, 1981 under 538-
36; submitted by O.M. Scott & Sons Co., Marysville, Ohio; CDL:245483-A)
00077863 DeCino, T.J. (1963) Letter sent to Walter M. Zeck dated Mar 14, 1963 (Toxicity and
repellency data on Bayer compounds): Report No. 11064. (Unpublished study,
including letters dated Mar 12, 1963 from T.J. DeCino to Thaddeus Parr, Mar 28, 1963
from W.M. Zeck to Farbenfabriken Bayer, A.G. and Apr 18, 1963 from T.J. DeCino to
Walter M. Zeck, received Jul 31, 1972 under 3125-213; submitted by Mobay Chemical
Corp., Kansas City, Mo.; CDL: 120480-H)
00078317 Uniroyal Chemical (1971) Reports of Investigations with Respect to the Safety of the
Pesticide Chemical: Vitavax Technical. (Unpublished study received on unknown date
under 3F1318; CDL: 098834-A)
00079217 Derr, H.J.; Mann, W.F., Jr. (1959) Guidelines for Direct-seeding Longleaf Pine. : U.S.
Forest Service, Southern Forest Experiment Station. (Occasional paper 171; pp. 5-9
148
-------
only; published study; CDL:245595-E)
00079218
00079504
00079505
00079506
00079507
00079678
00080222
00080894
00081626
Mann, W.F., Jr.; Derr, H.J. (1964) Guides for direct-seeding slash pine. : U.S. Forest
Service, Southern Forest Experiment Station. (U.S. Forest Service research paper SO-
12; pp. 10-13 only; published study; CDL:245595-F)
Johnston, R.L.; Bayer, R.B. (1959) Letter sent to E.S. Feenstra dated Feb 25, 1959:
Actidione-thiram fungicide 12,835~eye irritation in rabbits. (Unpublished study
received Nov 12, 1959 under unknown admin, no.; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL: 109631-C)
Johnston, R.L.; Bayer, R.B. (1959) Letter sent to E.S. Feenstra dated Feb 26, 1959:
Actidione-thiram fungicide (res. #12,835)-skin irritation in rabbits. (Unpublished study
received Nov 12, 1959 under unknown admin, no.; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL: 109631-D)
Johnston, R.J.; Bayer, R.B. (1959) Letter sent to E.S. Feenstra dated Feb 27, 1959:
Acti-dione-thiram Fungicide; res. #12,835-skin irritation in rabbits. (Unpublished study
received Nov 12, 1959 under unknown admin, no.; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL: 109631-G)
Johnston, R.L.; Bayer, RB. (1959) Letter sent to E.S. Feenstra dated Feb 27, 1959:
Acti-dione-thiram fungicide (12,835)~eye irritation in rabbits. (Unpublished study
received Nov 12, 1959 under unknown admin, no.; submitted by Upjohn Co.,
Kalamazoo, Mich.; CDL: 109631-H)
Baldwin, C.H., Jr. (1976) Letter sent to E.M. Bellet dated Sep 9, 1976 Greenhouse
evaluation of three soybean seed treatments. (Unpublished study received on unknown
date under 15382-14; prepared by Univ. of Missouri, Cooperative Extension Service,
submitted by Kalo Laboratories, Inc., Kansas City, Mo.; CDL: 235652-A)
Ralston Purina Company (1981) Thiram Technical; NB 84-106-1: RT Lab No. 874958.
(Unpublished study, including letter dated Jul 31, 1981 from G.D. Rosebery to Henry
M. Jacoby, received Aug 7, 1981 under 4581-258; submitted by Pennwalt Corp.,
Philadelphia,
Pa.; CDL:245765-A)
Anon. (1976) Planting treated seed does make a difference. Rice Farming (Mar):22-24.
(Also In unpublished submission received Dec 20, 1977 under 400-116; submitted by
Uniroyal Chemical, Bethany, Conn.; CDL:232528-B)
UCB S.A. Secteur Chimique (1981) Disulfure de Tetramethylthiuram (DTMT). (Also
In unpublished submission received Aug 24, 1981 under 1187-131; submitted by
Virginia Chemicals, Inc., Portsmouth, Va.; CDL:245858-A)
149
-------
00081627
00081633
00083289
00084300
00084301
00084745
00085516
00085521
00085531
Virginia Chemicals, Incorporated (1980) Chemistry of TMTD
(Tetramethylthiuramdisulfide). (Compilation; unpublished study received Aug 24, 1981
under 1187-131; CDL:245858-B)
Lambert, P. (1981) Letter sent to Don Coon dated Sep 7, 1981: Typical Analysis for
TMTD. (Unpublished study received on unknown date under 1187-131; submitted by
Virginia Chemicals, Inc., Portsmouth, Va.; CDL:245858-C)
E.I. du Pont de Nemours & Company, Incorporated (1957) Results of Tests on Amount
of Residue Remaining on Food Crops: Maneb. (Unpublished study received Nov 15,
1957 under PP0156; CDL: 090183-C)
Lambert, P. (1981) Letter sent to Don Coon dated Jul 9, 1981 (Typical analysis for
TMTD). (Unpublished study received Aug 24, 1981 under 45728-1; submitted by UCB
Chemicals Corp., Portsmouth, Va.; CDL:245977-A)
UCB Chemicals Corporation (1980) (Chemistry of Thiram). (Compilation; unpublished
study received Aug 24, 1981 under 45728-1; CDL:245977-B)
Cheah, M.L.; Avault, J.W., Jr.; Graves, J.B. (1978) Some Effects of Thirteen Rice
Pesticides on Crawfish Procambarus clarkii and P. acutus acutus. (Unpublished paper
presented at the 4th international symposium of the International Association of
Astacology; Aug 28-31, 1978, Thonon les Bains, France; unpublished study received
Oct 8, 1981 under 476-2107; prepared by Louisiana State Univ., Dept. of Entomology
and Fisheries Section, submitted by Stauffer Chemical Co., Richmond, Calif.;
CDL:246020-L)
Ackerson, C.W.; Mussehl, F.E. (1948) Toxicity of Treated Seed Corn in Rations For
Chicks. (Unpublished study received May 1, 1955 under PP0015; prepared by Univ. of
Nebraska, Depts. of Biochemistry and Nutrition and Poultry Husbandry, submitted by
California Spray-Chemical Corp., Richmond, Calif.; CDL:090983-F)
Meade, R.J.; Warner, D.R. (1954) The Effect of Seed Disinfectants, Orthocide and
Arasan, upon the Performance of Growing-fattening Swine. Swine progress rept. #328,
Summer 1954. (Unpublished study received May 1, 1955 under PP0015; prepared by
Univ. of Nebraska, Agricultural Experiment Station, submitted by California Spray-
Chemical Corp., Richmond, Calif.; CDL:090983-K)
Lacy, M.L. (1970) Letter sent to C.C. Compton dated Nov 30, 1970 (Determination of
Thiram residues in onions). (Unpublished study received Nov 1, 1970 under 1E1123;
prepared by Michigan State Univ., Dept. of Botany and Plant Pathology, submitted by
Interregional Research Project No. 4, New Brunswick, N.J.; CDL: 090898-B)
00086255
E.I. du Pont de Nemours & Company, Incorporated (1955) Name, Chemical Identity,
150
-------
and Composition: Thylate Thiram Fungicide. (Unpublished study received Nov 23,
1955 under PP0052; CDL: 092333-A)
00086256 E.I. du Pont de Nemours and Company (1955) Results of Tests on the Amount of
Residue Remaining on Apples: Thylate. (Unpublished study received Nov 23, 1955
under PP0052; CDL:092333-B)
00086257 E.I. du Pont de Nemours and Company (1955) Additional Data in Support of Petition:
Thiram. (Unpublished study received Nov 23, 1955 under PP0052; CDL:092333-C)
00086258 Lescanec, G.L.; Sorenson, P.; Wells, L.; et al. (1955) Dog Feeding Test with Thiram:
Report No. 66-55. Interim 3-month rept. (Unpublished study received Nov 5, 1955
under PP0052; submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.;
CDL: 092333-E)
00086940 Casanova, M.; Dubroca, J. (1973) Investigation of Residues of Various Fungicides
Used in the Treatment of Lettuce Crops under Grass. (France, Institut National dela
Recherche Agronomique, National Agronomic Research Centre, Phytopharmacy
Laboratory in cooperation with France, National Advisory Institute for Fruit, Vegetables
and Mushrooms, Crop Protection Service; unpublished study; CDL:070503-AU)
00086943 Wainwright, M.; Pugh, GJ.F. (1974) The effects of fungicides on certain chemical and
microbial properties of soils. Soil Biology and Biochemistry 6:263-267. (Also In
unpublished submission received Nov 17, 1981 under 1023-36; submitted by Upjohn
Co., Kalamazoo, Mich.; CDL:070503-AX)
00087908 Union Carbide Agricultural Products Company, Incorporated (1981) Confidential
Statement of Formula: Improved Rootone F with Fungicide. (Unpublished study
received Aug 7, 1981 under 264-29; CDL:246499-K)
00089408 E.I. du Pont de Nemours & Company (1958) Results of Tests on the Amount of
Residue Remaining on Food Crops: Thiram. (Unpublished study received Dec 15, 1958
under PP0204; CDL:090232-A)
00089409 E.I. du Pont de Nemours & Company (1958) Additional Data in Support of Petition:
Summary:Thiram. (Compilation; unpublished study, including published data, received
Dec 15, 1958 under PP0204; CDL:090232-B)
00089443 McGrath, J.T. (1957) Neuropathological Report on Dog Tissues: Tetramethyl Thiuram
Disulfide Study. (Unpublished study received Aug 4, 1957 under PP0144; submitted by
E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:090172-A)
00089444 Read, M.F.; Lescanec, G.; Hinkle, A.; et al. (1956) Dog Feeding Test with Thiram:
Report No. 13-57. (Unpublished study received Aug 4, 1957 under PP0144; submitted
by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:090172-B)
151
-------
00089460 E.I. du Pont de Nemours & Company, Incorporated (1957) Additional Data in Support
of Petition: Thiram. (Compilation; unpublished study, including published data,
received Aug 4, 1957 under PP0144; CDL:090172-D)
00089608 E.I. du Pont de Nemours & Company, Incorporated (1954) Summary of Toxicity
Information on Thiram. (Unpublished study received Feb 25, 1955 under PP0009;
CDL:090009-B)
00089609 E.I. du Pont de Nemours & Company, Incorporated (1954) Summary of Feeding
Studies with Thiram at the University of Rochester. (Unpublished study received Feb
25, 1955 under PP0009; CDL: 090009-C)
00089610 E.I. du Pont de Nemours & Company, Incorporated (1955) Results of Tests on the
Amount of Residue Remaining on Apples: Thiram. Includes method dated Dec 9, 1954.
(Unpublished study received Feb 25, 1955 under PP0009; CDL:090009-D)
00089669 FMC Corporation (1955) Results of Tests on the Amount of Residue Remaining and
Description of Analytical Methods: (Niacide M). Summary of studies 090168-J through
090168-M. (Unpublished study received Jun 3, 1957 under PP0140;
CDL:090168-F)
00089673 FMC Corporation (1955) (Niacide Residues—Apples). (Unpublished study received Jun
3, 1957 under PP0140; CDL:090168-M)
00089682 E.I. du Pont de Nemours & Company, Incorporated (1957) Results of Tests on the
Amount of Residue Remaining on Food Crops: Thiram. (Unpublished study received
Feb 26, 1958 under PP0170; CDL:090197-B)
00089813 Pease, H.L. (1953) Determination of Dithiocarbamate Fungicide Residues. Undated
method. (Unpublished study received Jun 4, 1957 under PP0132; submitted by E.I. du
Pont de Nemours & Co., Inc., Wilminigton, Del.; CDL:090162-B)
00089861 E.I. du Pont de Nemours & Company, Incorporated (1957) Results of Tests on the
Amount of Residue Remaining on Bananas: Thiram. (Unpublished study received Jun
13, 1968 under PP0359; CDL: 090389-B)
00089862 E.I. du Pont de Nemours & Company, Incorporated (1961) Thylate: Thiram Fungicide
for Control of Crown Rot and Surface Molds of Bananas. (Compilation; unpublished
study received Jun 13, 1968 under PP0359; CDL:090389-C)
00090157 E.I. du Pont de Nemours & Company, Incorporated (1960) Results of Tests on the
Amount of Residue Remaining on Celery: Thiram. (Unpublished study received Oct 20,
1960 under PP0278; CDL: 090300-A)
00090158 E.I. du Pont de Nemours & Company, Incorporated (1960) Control of Certain Diseases
of Celery with Thylate Thiram Fungicide and Combinations of Thylate with Manzate
152
-------
Maneb Fungicide or Parzate C Zineb Fungicide. (Compilation; unpublished study
received Oct 20, 1960 under PP0278; CDL:090300-B)
00090174 Pease, H.L. (1957) Determination of dithiocarbamate fungicide residues. Journal of the
Association of Official Agricultural Chemists 40(4): 1113-1118. (Also In unpublished
submission received Oct 20, 1960 under PP0278; submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, Del.; CDL:090300-C)
00090293 McCann, J. A. (1972) Tersan 75: Rainbow Trout ( Salmo gairdneri : Test No. 463. (U.S.
Agricultural Research Service, Pesticides Regulation Div., Animal Biology Laboratory,
Fish Toxicity Laboratory; unpublished study; CDL:130512-A)
00090294 McCann, J.A. (1972) Tersan 75: Bluegill (Lepomis macrochirus ): Test No. 446. (U.S.
Agricultural Research Service, Pesticides Regulation Div., Animal Biology Laboratory,
Fish Toxicity Laboratory; unpublished study; CDL:130513-A)
00090428 McCann, J.A. (1968) Niagara Niacide M Fungicide: Bluegill ( Lepomis
macrochirus): Test No. 114. (U.S. Agricultural Research Service, Pesticides Regulation
Div., Animal Biology Laboratory; unpublished study; CDL:130271-A)
00090873 Cummings, G.L. (1977) Letter sent to P.F. Smith dated Sep 27, 1977: Dygonate
stability. (Unpublished study received Dec 13, 1977 under 476-1995; submitted by
Stauffer Chemical Co., Richmond, Calif.; CDL:232472-B)
00093677 Lambert, P. (1981) Letter sent to D.E. Coon dated Nov 26, 1981 Chemistry of TMTD.
(Unpublished study received Dec 30, 1981 under 45728-1; submitted by UCB
Chemicals Corp., Portsmouth, Va.; CDL:246559-A)
00096647 Munnecke, D.E.; Domsch, K.H.; Eckert, J.W. (1962) Fungicidal activity of air passed
through columns of soil treated with fungicides. Phytopathology 52(Dec): 1298-1306.
(Also In unpublished submission received Mar 3, 1982 under 9386-15; submitted by
Vinings Chemical Co., Atlanta, Ga.; CDL:247007-B)
00097046 E.I. du Pont de Nemours & Company, Incorporated (1957) Determination of
Dithiocarbamate Residues. (Unpublished study received Jan 8, 1957 under unknown
admin, no.; CDL:124402-A)
00097047 E.I. du Pont de Nemours & Company, Incorporated (1956) EBDC's: Peach Residue
Data. (Compilation; unpublished study received Jan 8, 1957 under unknown admin, no.;
CDL:124402-B)
00097049 E.I. du Pont de Nemours & Company, Incorporated (1957) Summary of Thiram and
Dithiocarbamate Residue Data on Strawberries. (Unpublished study received Jan 8,
1957 under unknown admin, no.; CDL: 124402-D)
00097143 Herrick, C.A.; Holmes, C.E.; Degiusti, D.L. (1942) The experimental use of organic
153
-------
sulfur compounds for the prevention of cecal coccidiosis in chickens. American Journal
of Veterinary Research m(6): 117-127. (Also In unpublished submission received Aug
17, 1950 under unknown admin, no.; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, Del.; CDL:102833-A)
00098128 Prochimie International, Incorporated (1969) Chemistry Data on Thiram Fungicide.
(Compilation; unpublished study received Aug 27, 1969 under 8236-2; CDL:005995-
A)
00098129 Agway, Incorporated (1948) Chemistry Data on Marasperse C and Other Chemicals.
(Compilation; unpublished study received Mar 23, 1973 under 8590-432; CDL:021042-
B)
00098130 O.M. Scott & Sons Company (1967) A Summary Report for a Revised Proturf
Fertilizer Plus Fungicide Formula. (Unpublished study received Dec 28, 1967 under
538-36; CDL:023094-A)
00098131 Wisconsin Alumni Research Foundation (1967) Assay Report: WARF No. 7050038.
(Unpublished study received Dec 28, 1967 under 538-36; submitted by O.M. Scott &
Sons Co., Marysville, Ohio; CDL:023094-B)
00098132 E.I. du Pont de Nemours & Company, Incorporated (1956) Results of Tests on the
Amount of Residue Remaining on Peaches: Thiram. (Unpublished study received Sep
1, 1956 under PP0091; CDL: 090121-A)
00098133 Graham, C. (1955) Letter sent to Reed W. Varner dated Nov 8, 1955 Thylate for the
control ofpeach brown rot and scab. (Unpublished study received Aug 22, 1956 under
PP0091; prepared by Univ. of Maryland, Dept. of Entomology, Field Station, submitted
by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL: 092370-B)
00098134 E.I. du Pont de Nemours & Company, Incorporated (1958) Strawberry Fungicide
Experiment for Control of Gray Mold Rat~Thiram. (Compilation; unpublished study
received Jan 9, 1959 under PP0204; CDL:092481-B)
00098135 Breault, E.A. (1960) Letter sent to H.W. Gerritz dated Dec 13, 1960: Thiram
(tetramethyl thiuram disulfide) on celery. (U.S. Government; unpublished study;
CDL:092556-A)
00098136 E.I. du Pont de Nemours and Company (1960) Name, Chemical Identity, and
Composition: Thiram. (Unpublished study received Oct 12, 1960 under PP0278;
CDL:092556-B)
00098137 Rosen, D.E. (1962) Letter sent to William Stokes dated May 22, 1962 Thiram fungicide
residues in bananas. (Unpublished study received on unknown date under PP0359;
submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, Del.; CDL:092643-A)
154
-------
00098138 E.I. du Pont de Nemours and Company (1962) Name, Chemical Identity, and
Composition: Thiram. (Unpublished study received Apr 27, 1962 under PP0359;
CDL:092643-B)
00098139 E.I. du Pont de Nemours & Company, Incorporated (1955) Name, Chemical Identity
and Composition of the Fungicide: Thiram. (Unpublished study received Feb 25, 1955
under PP0052; CDL: 098736-A)
00098140 E.I. du Pont de Nemours and Company, Incorporated (1955) Results of Tests on the
Amount of Residue Remaining on Apples: Thiram. (Unpublished study received Feb
25, 1955 under PP0052; CDL: 098736-B; 098154)
00098141 E.I. du Pont de Nemours & Company, Incorporated (1954) Summary of Biological
Data: Thiram. (Compilation; unpublished study received Feb 25, 1955 under PP0052;
CDL:098736-C)
00098142 E.I. du Pont de Nemours & Company, Incorporated (1959) Thiram: Residues in
Peaches and Strawberries. (Compilation; unpublished study received on unknown date
under PP0204;CDL: 098740-A)
00098143 E.I. du Pont de Nemours & Company, Incorporated (19??) Residue (ppm): Thiram:
Whole Fruit. (Unpublished study received on unknown date under PP0359;
CDL:098907-A)
00098149 Anon. (1955) Thiram on Apples. (Unpublished study received Dec 20, 1955 under
unknown admin, no.; submitted by ; CDL: 124401-A)
00098150 E.I. du Pont de Nemours & Company, Incorporated (1959) Thiram Fungicide Residues
in Peaches and Strawberries. (Compilation; unpublished study received Jan 19, 1959
under PP0204; CDL: 126219-A)
00098151
00098154
R.T. Vanderbilt Company, Incorporated (1960) Vangard (R) GF Wettable Powder,
Experimental Fungicide-Wettable Powder. (Unpublished study received Jul 19, 1960
under 1965-EX-4; CDL: 126748-A)
Dymo-Tech Company (1966) Report on Application and Performance of Rodent-repel.
(Unpublished study received Mar 7, 1968 under 9685-2; CDL:220342-A)
00098155 W.A. Cleary Corporation (1976) Toxicity of Thiram Turf Fungicide to Rats and Albino
Rabbits. (Compilation of reports by U.S. Environmental Protection Agency,
Pharmacology Laboratory; unpublished study; CDL:225962-A)
00098156 Eibert, J., Jr. (1966) Toxicity Study of Kromad to Young Bluegill Fish: S.A. No. R-
1364. (Unpublished study received Apr 14, 1966 under 372-24; prepared by Scientific
Associates, Inc., submitted by Mallinckrodt, Inc., St. Louis, Mo.; CDL:226534-A)
00098157 White, H. (1976) Kalo Formulation Q1360876: Acute Oral Toxicity in Rats: Study No.
155
-------
00098158
00098159
00098160
00098161
00098162
00098163
00098164
00098165
00098166
00098167
974-004-101-0976. (Unpublished study received Nov 24, 1976 under 15382-14;
submitted by Kalo Laboratories, Inc., Kansas City, Mo.; CDL:226989-B)
White, H. (1976) Kalo Formulation Q1360876: Primary Skin Irritation Study in
Rabbits: Study No. 124-009-404-1076. (Unpublished study received Nov 24, 1976
under 15382-14; submitted by Kalo Laboratories, Inc., Kansas City, Mo.; CDL:226989-
E)
Roberts, S.; Wineholt, R.L. (1976) Static 96-hour Toxicity Study of TNL to Daphnids:
Laboratory No. 6E-3283. (Unpublished study received Nov 24, 1976 under 15382-14;
prepared by Cannon Laboratories, Inc., submitted by Kalo Laboratories, Inc., Kansas
City, Mo.;
CDL:226989-H)
Kalo Laboratories, Incorporated (1975) Determination of Thiram by Ultraviolet
Spectroscopy. (Unpublished study received Nov 24, 1976 under 15382-14;
CDL:226989-I)
Kalo Laboratories, Incorporated (1975) Determination of Thiram by Infrared
Spectroscopy. (Unpublished study received Nov 24, 1976 under 15382-14;
CDL:226989-J)
Kalo Laboratories, Incorporated (1976) Efficacy Data for TripleNoctin L. (Compilation;
unpublished study received Nov 24, 1976 under 15382-14; CDL:226989-K)
Midwest Research Institute (1976) Thiram: MRI Project No. 4307-L; RvR Project No.
78; Contract No. 68-01-4198. (RvR Consultants for U.S. Environmental Protection
Agency, Officeof Pesticide Programs, Criteria and Evaluation Div.; unpublished study;
CDL: 231591-A)
E.I. du Pont de Nemours and Company (1978) ArasanA(R)170-S Seed Protectant:
Nitrosamine Analysis. (Unpublished study received Jun 27, 1978 under 352-322;
CDL:234219-A)
Maurer, C.H. (1975) Formulation Request: NL Ag. No. 053. (Unpublished study
received Jun 21, 1978 under 1001-11; prepared by NL Industries, submitted by W.A.
Cleary Corp., Somerset, N.J.; CDL:234442-A)
W.A. Cleary Corporation (1978) Tetramethylthiuram Disulfide. (Unpublished study
received Jun 21, 1978 under 1001-11; CDL: 234442-B)
Shapiro, R. (1978) Letter sent to Clayton C. Nelson dated Feb 23, 1978 Analytical
values for thiram on Cleary products. (Unpublished study received Jun 21, 1978 under
1001-11; prepared by Nutrition International, Inc., submitted by W.A. Cleary Corp.,
Somerset, N.J.; CDL:234442-C)
156
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00098168 Hamrick, W.J. (1967) The Effects of Arasan-endrin Treated Pine Seed on Bobwhite
Quail, Gray Squirrel and Turkey. Master's thesis. (Unpublished study received Jul 1,
1964 under 2935-352; submitted by W.A. Cleary Corp., Somerset, N.J.; CDL:235183-
A)
00098170 Wilbur Ellis Company (1971) Tests of Chemical Repellents for Direct Seeding.
(Compilation; unpublished study, including AL-1.51, AL-1.53, AL-1.59, received Jul 1,
1964 under 2935-352; CDL:235183-C)
00098171 Wilbur Ellis Company (1968) Seed Protectants for Direct Seeding. (Compilation;
unpublished study received Jul 1, 1974 under 2935-352; CDL:235184-A)
00098172 Wilbur Ellis Company (1968) Bird Repellents for Direct Seeding. (Compilation;
unpublished study received on unknown date under 2935-352; CDL:235185-A)
00098174 U.S. Fish and Wildlife Service, Wildlife Research Laboratory (1956) 1956 Formulation
for the Treatment of Coniferous Tree Seed. (Unpublished study; CDL:235185-C)
00098175 Kalo Laboratories, Incorporated (1977) Studies of the Chemical Thiram. (Compilation;
unpublished study received Feb 10, 1978 under 15382-14; CDL:235929-A)
00098176 Pennwalt Corporation (1978) Studies of the Chemical Methyl Thiram. (Compilation;
unpublished study received Jan 25, 1979 under 4581-258; CDL:236834-A)
00098177 Raltech Scientific Services, Incorporated (1979) Technical Thiram Pesticide: NB 84-
106-1: Lab No. 717306. (Unpublished study received Apr 20, 1979 under 4581-258;
submitted by Pennwalt Corp., Philadelphia, Pa.; CDL:238213-A)
00098178 Raltech Scientific Services, Incorporated (1979) Technical Thiram Pesticide: NB 84-
106-2: Lab No. 717307. (Unpublished study received Apr 20, 1979 under 4581-258;
submitted by Pennwalt Corp., Philadelphia, Pa.; CDL:238213-B)
00098190 E.I. du Pont de Nemours & Company, Incorporated (1957) Results of Tests on Amount
of Residue Remaining on Food Crops: Thiram. Includes undated method entitled:
Determination of dithiocarbamate fungicide residues. (Compilation; unpublished study
received Aug 4, 1957 under PP0144; CDL:090172-C)
00098206 FMC Corporation (1957) Reasonable Grounds in Support of Petition: (Niacide M).
(Unpublished study received Jun 3, 1957 under PP0140; CDL:090168-N)
00098644 Cull en, T.E. (1964) Spectrophotometric determination of dithiocarbamate residues on
food crops. Analytical Chemistry 36(1): 221-224. (Also In unpublished submission
received Nov 16, 1965 under unknown admin, no.; submitted by FMC Corp.,
Philadelphia, Pa.; CDL: 120299-A)
157
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00098799
00098830
00098832
00098833
00098839
00098850
00098851
00098852
00098853
Kemin Industries, Incorporated (1965) Chemistry of Captan. (Compilation; unpublished
study received Jun 11, 1965 under 8596153; CDL:107239-A)
Griffith, R.L.; Matthews, S. (1969) The persistence of soil of the fungicidal seed
dressings captan and thiram. Annals of Applied Biology 64:113-118. (Also In
unpublished submission received Jan 4, 1978 under 239-1246; submitted by Chevron
Chemical Co., Richmond, Calif.; CDL:232569-F)
Kluge, E. (1969) On the Duration of the Effect of Thiuram, Ferbam and Captan in
Forest Soils. A translation of: Without Title. Archiv fuer Pflanzenschutz 5(l):39-53.
(Unpublished study received Jan 4, 1978 under 239-1246; submitted by Chevron
Chemical Co., Richmond, Calif.; CDL:232569-I)
Kluge, E. (1969) The Effect of the Soil Reaction on the Degradation and Persistence of
Thiuram, Ferbam, and Captan in the Soil. A translation of: Without Title. Archiv furer
Pflanzenwchutz, 5(4):263-271. (Unpublished study received Jan 4, 1978 under 239-
1246; submitted by Chevron Chemical Co., Richmond, Calif.; CDL:232569-J)
Munnecke, D.E. (1961) Movement of nonvolatile, diffusible fungicides through
columns of soil. Phytopathology 51(Sep):593-599. (Also In unpublished submission
received Jan 4, 1978 under 2391246; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL: 232569-S)
Tews, L.L. (1971) The effects of selected fungicides and soil fumigants upon the
microfungi of a cattail marsh. Proc. 14th Conf. Great Lakes Res. 14:128-136. (Also In
unpublished submission received Jan 4, 1978 under 239-1246; submitted by Chevron
Chemical Co., Richmond, Calif.; CDL:232570-G)
Naumann, K. (1977) On the Dynamics of the Soil-microflora after Application of the
Fungicides Olpisan(Trichlorodinitrobenzene), Captan, and Thiuram. A translation of:
Without title. Archiv fuer Pflanzenschutz 6(5):383-398. (Unpublished study received
Jan 4, 1978 under 239-1246; submitted by Chevron Chemical Co., Richmond, Calif.;
CDL:232570-H)
Domsch, K.H. (1977) The Effect of Soil Fungicides, m. Quantitative Changes of the
Soil Flora.A translation of: Without title. Zeitschrift fuer Pflanzenkrankheiten und
Pflanzenschutz LXVI(l): 17-26. (Unpublished study received Jan 4, 1978 under 239-
1246; submitted by Chevron Chemical Co., Richmond, Calif.; CDL:232570-K)
Domsch, K.H. (1977) The Effect of Soil Fungicides. IV. Changes in the Spectrum of
the Soil Fungi. A translation of: Without title. Zeitschrift fuer Pflanzenkrankheiten und
Pflanzenschutz 67(3): 129-150. (Unpublished study received Jan 4, 1978 under 239-
1246; submitted by Chevron Chemical Co., Richmond, Calif.; CDL:232570-L)
158
-------
00099581 Phelps Dodge Refining Co. (1974) Copper Sulfate Pentahydrate: Topical Application to
Skin and Allergy. (Unpublished study received Jul 12, 1978 under 1278-8;
CDL:234672-A)
00099594 Grolleau, G. (1965) Toxicity of Seed-dressing Products for Partridge and Pheasant.
(Unpublished study received Nov 22, 1978 under 42567-1; prepared by Centre National
de Recherches Zootechniques, France, submitted by La Quinoleine S.A., c/o
Registration Consulting Assoc., Pacifica, CA; CDL:237443-E)
00100443 Smith, J.; Leader, G.; Weiser, J.; et al. (1978) Report of Analysis: Methyl Thiram: Anal.
Lab No. 780210.8. (Unpublished study received Jan 25, 1979 under 4581-258;
submitted by Pennwalt Corp., Philadelphia, PA; CDL:236834-A)
00100444 Chang, S.; Harrington, G. (1975) Determination of dimethylnitrosamine and
nitrosoproline by differential pulse polarography. Analytical Chemistry 47(11): 1857-
1860. (Also In unpublished submission received Jan 25, 1979 under 4581-258;
submitted by Pennwalt Corp., Philadelphia, PA; CDL:236834-B)
00100445 Smith, J.; Leader, G. (1978) Report of Analysis: Thiram, Technical: Anal. Lab No.
780601.38. (Unpublished study received Jan 25, 1979 under 4581-258; submitted by
Pennwalt Corp., Philadelphia, PA; CDL:236834-D)
00100497 Paik, S.G.; Lee, S.Y. (1977) Genetic effects of pesticides in the mammalian cells n.
Mutagenesis in L5178Y cells and DNA repair induction. Korean Journal of
Zoology 20(4):159-168. (Also In unpublished submission received Apr 27, 1982 under
707-88; submitted by Rohm & Haas Co., Philadelphia, Pa.; CDL:070802-M)
00101429 E.I. du Pont de Nemours & Co., Inc. (1957) Residues of Ferbam in Peaches and Other
Crops. (Compilation; unpublished study received Dec 10, 1957 under 352-162;
CDL:002754-A)
00101430 Zapp, J. (1963) Safety of Ferbam as a Pesticide Residue. (Unpublished study received
Dec 25, 1962 under PP0393; submitted by E.I. du Pont de Nemours & Co., Inc.,
Wilmington, DE; CDL: 092680-A)
00101437 E.I. du Pont de Nemours & Co., Inc. (1960) Residues of Ferbam in Tomatoes.
(Compilation; unpublished study received Dec 15, 1960 under unknown admin, no.;
CDL: 119741-A)
00103373 Midwest Research Institute (1977) Initial Scientific Review of Thiram: MRI Project No.
4307-L; RvR Project No. 78. (Unpublished study received Jun 15, 1982 under
unknown admin, no.; prepared in cooperation with RvR Consultants, submitted by
Bonide Chemical Co., Inc., Yorksville, NY; CDL:247670-A)
00105332 U.S. Fish and Wildlife Service (1965) Wildlife studies by the cooperative wildlife
research units. Pages 49-50, In The Effects of Pesticides on Fish and Wildlife: 1964.
159
-------
(SI): USFWS. (Published study; CDL:005106-C)
00105372 Alexandrescu, S.; Serban, M. (1966) Toxicitatea unor insecticide fata de albine,
determinata in laborator si camp. Toxicity to bees of some insecticides, as determined
by laboratory and field tests. An. Inst. Cercet. Prol. Plant, Inst. Cent. Cercet. Agr.
IV:411-417. (Rumanian text; also In unpublished submission received Nov 1, 1970
under unknown admin, no.; submitted by Hercules, Inc., Agricultural Chemicals,
Wilmington, DE; CDL: 005103-AN)
00105560 Wojtowski, F.; Hess, E.; Wiolkaniec, Z. (1969) Toxicity of more important pesticides to
honey bees. Biul. Inst. Ochr. Rosi. 44: 249-261. Taken from: Source unknown.
(Abstract 2935q; alsoln unpublished submission received Sep 17, 1975 under 1F1118;
submitted by Hercules, Inc., Wilmington, DE; CDL:094610-AS)
00106606 Wainwright, M.; Pugh, G. (1973) The effect of three fungicides on nitrification and
ammonification in soil. Soil Biology and Biochemistry 5:577-584. (Also In unpublished
submission received Jan 4, 1978 under 239-1246; submitted by Chevron Chemical Co.,
Richmond, Calif.; CDL:232570-D)
00106621 E.I. du Pont de Nemours and Co. (1968) Thiram Technical Data Sheet. (Unpublished
study received Mar 13, 1967 under 334-263; submitted by Hysan Corp., Chicago, IL.;
CDL:002611-A)
00106622 Lawn Medic, Inc. (1972) Thiram Fungicide. (Compilation; unpublished study received
Jan 25, 1974 under 33625-5; CDL: 012087-A)
00106623 Kalo Laboratories, Inc. (1972) Thiram: Chemical Data. (Compilation; unpublished
study received Nov 24, 1976 under 15382-15; CDL:226990-A)
00106624 Kalo Laboratories, Inc. (1972) Thiram: Stand-UpA(TM)I: Chemical, Physical and
Technical Data. (Compilation; unpublished study received Nov 24, 1976 under 15382-
14; CDL:226989-A)
00108644 E.I. du Pont de Nemours & Co., Inc. (1970) Efficacy of Bird Repellents and Various
Products Used against Tree Diseases. (Compilation; unpublished study received Aug
15, 1958 under 352218; CDL:023236-A)
00115487 Markert, S.; Kundler, P. (1975) Model Trials to Test the Effect of Commercial
Pesticides on Nitrogen Decomposition in the Soil. Modelversuche zum Einfluss von
Handelsublichen Pflanzenschutzmitteln auf die Stickstoffumetzungen im Boden: Code
102-1699. (Translation from German; unpublished study received Sep 17, 1979 under
748-224; prepared by Academy for Agricultural Sciences of the German Democratic
Republic, Institute for Fertilizer Research Leipzig-Potsdam, W. Ger., submitted by PPG
Industries, Inc., Barberton, OH;
CDL:240988-AA)
160
-------
00115967
00118352
00118355
00120275
00122804
00125425
00126234
00126237
00126238
00126239
00126240
Office of Commissioner (1968) Study: Pesticide Residues in Selected Crops.
(Compilation; unpublished study received Feb 21, 1969 under 7E0598; CDL:090766-
A)
Olefir, A.; Vinogradova, V. (1968) Embryotropic effect of the pesticides Sevin and
Cyram. Inst. Gig. Tr. Profzabol., Kiev, USSR, Vrach. Delo (11): 103-106. Taken from:
Chem. Abstracts v.70. (Abstract 19205n; also In unpublished submission received May
15, 1970 under 0F0902; submitted by Union Carbide Corp., New York, NY;
CDL:091556-P)
Robens, J. (1969) Teratologic studies of carbaryl, diazinon, norea, disulfiram, and
thiram in small laboratory animals. Toxicology and Applied Pharmacology 15:152-163.
(Also In unpublished submission received May 15, 1970 under 0F0902; submitted by
Union Carbide Corp., New York, NY; CDL:091556-S)
Reactor Products, Inc. (1982) Chemistry of React-Rite. (Compilation; unpublished
study received Feb 3, 1982; May 24, 1982 under 46588-1; CDL:247560-A)
UCB Chemicals Corp. (1982) Chemical Study of Thiram Technical Micropearls.
(Compilation; unpublished study received Dec 9, 1982 under 45728-2; CDL:249110-A)
Tappan, W.; Lawson, F.; May, L.; et al. (1962) Taste Tests with 1962 Crop Florida
Cigar Wrappers. (Unpublished study received Feb 24, 1964 under 464-324; prepared by
Budd Cigar Co. and Others, submitted by Dow Chemical U.S.A., Midland, MI; CDL:
003522-C)
Glenn, M.; Burr, W. (1968) Acti-Dione Thiram (Cycloheximide 0.75%): Acute Oral
Toxicity (LD50) in the Rat: 006-9610-5. (Unpublished study received Mar 8, 1983
under 1023-10; submitted by Upjohn Co., Kalamazoo, MI; CDL:249644-Q)
Glenn, M.; Moe, L. (1968) Acute (One-hour) Inhalation Exposure of Rats to Dust
Aerosol of Acti-Dione Thiram—Part I: Ref. 0069610-11. (Unpublished study received
Mar 8, 1983 under 1023-10; submitted by Upjohn Co., Kalamazoo, MI; CDL:249644-
U)
Glenn, M.; Moe, L. (1968) Acute (One-hour) Inhalation Exposure of Rats to Dust
Aerosol of Acti-Dione Thiram—Part II: Ref. No. 006-9610-12. (Unpublished study
received Mar 8, 1983 under 1023-10; submitted by Upjohn Co., Kalamazoo, MI; CDL:
249644-V)
Glenn, M.; Moe, L. (1968) One-hour Inhalation Exposure of Rats to Dust Aerosol of
Acti-Dione Thiram: Ref. No. 006-9610-21. (Unpublished study received Mar 8, 1983
under 1023-10; submitted by Upjohn Co., Kalamazoo, MI; CDL:249644-W)
Weddon, T.; Field, C. (1975) Acti-Dione Thiram Chloroneb Primary Skin Irritation in
Rabbits: 001-9610-TEW-75-6. (Unpublished study received Mar 8, 1983 under 1023-
161
-------
00126241
00126427
00128154
00129609
00135504
00135510
00135584
00135587
00135613
00135614
10; submitted by Upjohn Co., Kalamazoo, MI; CDL:249644-X)
Weddon, T.; Field, C. (1975) Acti-Dione Thiram Chloroneb Eye Irritation Study in
New Zealand Rabbits: 001-9610-TEW-75-5. (Unpublished study received Mar 8, 1983
under 1023-10; submitted by Upjohn Co., Kalamazoo, MI; CDL:249644-Y)
Upjohn Co. (1983) Powder Cycloheximide: Product Chemistry. (Compilation;
unpublished study received Mar 8, 1983 under 1023-10; CDL:249643-A)
Kuthubutheen, A.; Pugh, G. (1979) The effects of fungicides on soil fungal populations.
Soil Biol. Biochem. ll(3):297-303. (Also In unpublished submission received Apr 21,
1983 under 1023-36; submitted by Upjohn Co., Kalamazoo, MI; CDL:071566-A)
Read, M.; Lescanec, G.; Hinkle, A.; et al. (1957) Dog Feeding Test with Thiram:
Medical Research Project No. MR-324; Report No. 13-57. (Unpublished study
received Jul 27, 1983 under 352-220; submitted by E.I. du Pont de Nemours & Co.,
Inc., Wilmington, DE; CDL:250849-A)
E.I. du Pont de Nemours & Co., Inc. (1955) Biological Justification for Semesan T Turf
Fungicide and Use of a Mercurial in Combination with Tersan 75 Thiram Fungicide.
(Unpublished study received Jan 13, 1956; Dec 2, 1955 under 352-160; CDL:002751-
A)
Ashworth, L. (1963) Letter sent to T. Ryker dated Aug 23, 1963 Arasan and Panogen
use data. (Unpublished study received Feb 20, 1964 under 352-169; prepared by
Agricultural and Mechanical College of Texas, Dept. of Plant Sciences, Teaching,
Research, Extension, submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington,
DE; CDL:002766-A)
W. A. Cleary Corp. (1969) Efficacy of Bromosan and Other Fungicides. (Compilation;
unpublished study received Jan 20, 1970 under 1001-46; CDL:005006-A)
Hendrix and Dail, Inc. (1970) Phytotoxicity of Arasan 75 and Cleary 3336 Mixtures to
Bent Grass. (Unpublished study received Jan 12, 1971 under 1001-51; submitted by W.
A. Cleary Corp., Somerset, NJ; CDL:005008-A)
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting the Use of Thiram
Fungicide for Seed Protection on Wheat, Barley, Rye and Flax. (Compilation;
unpublished study received Apr 2, 1970 under 352-322; CDL:002969-A)
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting the Use of Thiram
Fungicide for Seed Protection on Safflower. (Compilation; unpublished study received
Jun 9, 1970 under 352-322; CDL: 002970-A)
162
-------
00135615
00135860
00135861
00135862
00135869
00136512
00136891
00136892
00136893
00136894
00136895
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting Use of Thiram Fungicide
for Seed Protection of Reginned and Fuzzy Cottonseed. (Compilation; unpublished
study received Aug 27, 1970 under 352-322; CDL:002971-A)
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting the Use of Thiram
Fungicide for Seed Protection on Wheat, Barley, Rye and Flax. (Compilation;
unpublished study received Apr 2, 1970 under 352-240; CDL:002805-A)
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting Use of Thiram Fungicide
for Seed Protection of Reginned and Fuzzy Cottonseed. (Compilation; unpublished
study received Aug 27, 1970 under 352-240; CDL:002807-A)
E.I. du Pont de Nemours & Co., Inc. (1971) Data Supporting Use of Arasan 42-S
Thiram Fungicide and Repellent at a Seed Treating Rate of 4 Oz. per Cwt. of Rice in
California. (Compilation; unpublished study received May 6, 1971 under 352-240;
CDL: 002808-A)
E.I. du Pont de Nemours & Co., Inc. (1970) Data Supporting the Use of Thiram
Fungicide for Seed Protection on Safflower. (Compilation; unpublished study received
Jun 8, 1970 under 352-277; CDL:002901-A)
Ledeober, F.; Simmons, J.; Kido, G.; et al. (1962) The Control of Moss Selaginella spp
in Lawns with a Dry Granular Formulation of Phenyl Mercury and Thiram.
(Unpublished study received Jan 15, 1963 under 538-5; submitted by O.M. Scott &
Sons Co., Marysville, OH; CDL:004050-A; 004051)
E.I. du Pont de Nemours & Co., Inc. (1958) Efficacy of Thiram Suspension 40 Seed
Disinfectant and Protectant and Thiram-Dieldrin Suspension Seed Protectant.
(Compilation; unpublished study received May 15, 1958 under 352-240; CDL:002796-
A)
E.I. du Pont de Nemours & Co., Inc. (1958) Biological Justification: Arasan 42-S
Thiram Seed Disinfectant and Protectant for Rabbit and Deer Repellency. (Unpublished
study received Nov 5, 1958 under 352-240; CDL:002797-A)
E.I. du Pont de Nemours & Co., Inc. (1959) Biological Justification for Arasan 42-S in
Modified Repellent Usage. (Compilation; unpublished study received Sep 29, 1959
under 352-240; CDL: 002798-A)
E.I. du Pont de Nemours & Co., Inc. (1960) Biological Justification for Proposed
Revised Labeling of Arasan 42-S Thiram Seed Disinfectant and Protectant for Animal
Repellent Usage. (Compilation; unpublished study received Dec 1, 1960; Nov 18, 1960
under 352-240; CDL:002799-A)
Metzer, R. (1960) Field Mold Control with Arasan 42-S To Improve the Appearance
and Quality of Sorghum Seed. By Agricultural and Mechanical College of Texas,
163
-------
00136896
Agricultural Experiment Station. SI: s.n.. (Sep; also In unpublished submission
received Nov 21, 1960
under 352-240; submitted by E.I. du Pont de Nemours & Co., Inc., Wilmington, DE;
CDL:002800-A)
E.I. du Pont de Nemours & Co., Inc. (1963) Biological Justification for Use of Arasan
75 and Arasan 42-S in Treating Coniferous Seeds. (Compilation;unpublished study
received Jul 7, 1964 under 352-240; CDL:002802-A)
00136897 E.I. du Pont de Nemours & Co., Inc. (1964) Biological Justification for Proposed
Revision of Arasan 42-S Thiram Fungicide and Repellent Label GC 18114: 3-61.
(Compilation; unpublished study received Jul 7, 1964 under 352-240; CDL:002803-A)
00136898 Hodges, C. (1969) Letter sent to J. Ohman dated Jan 15, 1969: Disease control
(chemical). (Unpublished study received May 14, 1969 under 352-240; prepared by
U.S. Forest Service, Forestry Sciences Laboratory, submitted by E.I. du Pont de
Nemours & Co., Inc., Wilmington, DE; CDL:002804-A)
00136936 Mallinckrodt, Inc. (1955) Efficacy of Various Fungicides for Control of Turf Diseases.
(Compilation; unpublished study received Dec 14, 1955 under 372-24; CDL:003198-A)
00136937 Mallinckrodt, Inc. (1956) Kromad: Supporting Data for the Western Section of the
United States. (Compilation; unpublished study received Jan 12, 1956 under 372-24;
CDL:003199-A)
00137354 E.I. du Pont de Nemours & Co., Inc. (1955) Biological Justification for Semesan T Turf
Fungicide and Use of a Mercurial in Combination with Tersan 75 Thiram Fungicide.
(Compilation; unpublished study received Dec 2, 1955 under 352-160; CDL:005834-A)
00138221 Antonovich, Y.; Chernov, O.; Samosh, L.; et al. (1970) A Comparative Toxicological
Evaluation of Dithiocarbamates. (Unpublished study received Apr 10, 1984 under
3F2964; submitted by Rhone-Poulenc, Inc., Monmouth Junction, NJ; CDL:072566-A)
00139125 U.S. Environmental Protection Agency (1977) Efficacy of Vitavax—R Flowable
Fungicide.
00140015 Week, F.J. (1974) Letter sent to Don Freeman dated Mar 28, 1974 Data on Repel.
(Unpublished study received Jun 24, 1974 under 20215-1; prepared by Friedrich J.
Week Co., submitted by Alcor Products, Carlsbad, Calif.; CDL:051047-E)
00140290 Matsushita, T.; Yoshioka, M.; Aoyama, K.; et al. (1978) Experimental study on contact
hypersensitivity caused by dithiocarbamate fungicides ferbam, ziram and their related
compounds. Acta Medica Universitatis Kagoshimaensis 20:99-106. (Also In
unpublished submission received Apr 10, 1984 under 3F2964; submitted by Rhone-
Poulenc, Inc., Monmouth Junction, NJ; CDL:072566-B)
00140837 E.I. du Pont de Nemours & Company, Incorporated (1955) Reports of Investigations
164
-------
Made with Respect to Safety of Thiram. (Unpublished study received Nov 23, 1955
under PP0052; CDL:092333-D)
00141047 Baer, R.; Ramsey, D.; Biondi, E. (1973) The most common contact allergens 1968-
1970. Arch. Dermatol. 108(l):74-78.
00141175 Goyings, L.; Kaczkofsky, H. (1968) The Acute Dermal LD50 of ActiDione Thiram in
Rabbits: Reference No. 006-9610-17. Unpublished study prepared by Upjohn Co. 7 p.
00141487 Gustafson, Inc. (1984) Product Chemistry Information: [Baytan Fungicides],
Unpublished compilation. 17 p.
00141618 Chipman Inc. (19??) Product Chemistry Statement: [Agrosol Pour-on Systemic Soybean
Seed Treatment Fungicide], Unpublished compilation. 48 p.
00141849 Hughes, T. (1984) Acute Oral Median Lethal Dosage Study in Rats; Acute Dermal
Toxicity Screen in Rabbits; Primary Skin Irritation Study in Rabbits; Primary Eye
Irritation Study in Rabbits of Seed Treatment 4LB Thiram: Project No. 84-0680-21. 33
P-
00141850 Platte Chemical Co. (1984) Product Chemistry: Thiram Flowable (Undyed).
Unpublished study. 2 p.
00142838 Thiram Task Force (19??) [National Library of Medicine's Bibliographic Citation List
for Thiram], Unpublished compilation. 225 p.
00143624 Gustafson, Inc. (19??) Product Chemistry Data: Anchor Flowable Fungicide.
Unpublished study, lip.
00143803 Thiram Task Force (19??) (Residue Tolerance and Allowable Daily Intake Information
on Thiram). 12 p.
00143804 Brusick, D. (1976) Mutagenicity Evaluation of Bi0-76-277 Thiurad ...: Final Report:
LBI Project No. 2683. Unpublished study prepared by Litton Bionetics, Inc. 13 p.
00143805 Matheson, D. (1978) Mutagenicity Evaluation of Bio-77-324 Thiurad in the Mouse
Lymphoma Forward Mutation Assay: Final Report: LBI Project No. 20839.
Unpublished study prepared by Litton Bionetics, Inc. 13 p.
00143806 Nowak, E. (19??) [Mutagenicity Test: TMTD-Bayer: 7780-26-2] Unpublished study. 9
P-
00143808 Thiram Task Force (19??) Mutagenicity Testing of Thiram,
Bis(dimethylthiocarbamoyl) Disulfide. Unpublished study. 5 p.
00143810 Foster, T. (1973) Physiological and biological effect of pesticide residues in poultry. 69-
165
-------
121.
00143811 Thiram Task Force (1985) Thiram Toxicology: Bibliographic Study for the Period
1950-1978 [Including Supplements Which Extend to the Year 1979], Unpublished
summary. 111 p.
00143812 Smyth, H.; Weil. C. (1966) Chronic oral toxicity to rats of a vinyl chloride-vinyl acetate
copolymer. Toxicology and Applied Pharmacology 9(3):501-504.
00143813 Gebhardt, D.; van Logten, M. (1968) The chick embryo test as used in the study of the
toxicity of certain dithiocarbamates. Toxicology and Applied Pharmacology 13(3):316-
324.
00143814 Dubois, K.; Raymund, A.; Hietbrink, B. (1961) Inhibitory action of dithiocarbamates on
enzymes of animal tissues. Toxicology and Applied Pharmacology 3:236-255.
00143815 International Agency for Research on Cancer (1976) IARC Monographs on the
Evaluation of the Carcinogenic Risk of Chemicals to Man: Some Carbamates,
Thiocarbamates and Carbazides: Volume 12. Incomplete. World Health Organization.
236 p.
00143816 Short, R; Russel, J.; Minor, J.; et al. (1976) Developmental toxicity of ferric
dimethyldithiocarbamate and bis(dimethylthiocarbamoyl)disulfide in rats and mice.
Toxicology and Applied Pharmacology 35:83-94.
00143817 Lee, C.; Russell, J.; Minor, J. (1978) Oral toxicity of ferric dimethyl dithiocarbamate
(ferbam) and tetramethylthiuram disulfide (thiram) in rodents. Journal of Toxicology
and Environmental
Health 4:93-106.
00143818 Johnson, E.; Waibel, P.; Pomeroy, B. (1955) The toxicity of arasantreated corn to hens
and chicks. Proc. Am. Vet. Med. Assoc. 92: 322-323.
00143819 Rasul, A.; Howell, M. (1974) The toxicity of some dithiocarbamate compounds in
young and adult domestic foul. Toxicology and Applied Pharmacology 30(l):63-78.
00143820 Ackerson, C.; Mussehl, F. (1955) Toxicity of treated seed corn in rations for chicks.
Poultry Sci. 34:728-729.
00143821 Waibel, P.; Johnson, E.; Pomeroy, B.; et al. (1957) Toxicity of tetramethylthiuram
disulfide for chicks, poults, and goslings. Poultry Sci. 36:697-703.
00143822 Lee, C.; Peters, P. (1976) Neurotoxicity and behavioral effects of thiram in rats.
Environmental Health Prespectives 17:35-43.
00143823 Roll, R. (1971) Teratologische untersuchungen mit thiram (TMTD) an zwei
166
-------
00143824
00143825
00143826
00143827
00143828
00143829
00143830
00143832
00143833
00143834
00143835
00143836
00143837
maeusestammen [Teratologic studies with thiram (TMTD) on two strains on mice].
Arch. Toxicol. 27:173-186.
Egberts, J.; Roos, J.; Beijer, H. (1972) The toxicity of TMTD in japanese quail, an
experimental study. TNONieuws 27(10):594598.
Ayanaba, A.; et al. (1974) [Title page missing; Topic -Conversion of thiram to
nitrosamines in sewage and lake water], J. Environ. Quality 3(l):84-89.
Tomlinson, T.; Boon, A.; Trotman, C. (1966) Inhibition of nitrification in the activated
sludge process of sewage disposal. J. Appl. Bact. 29(2):266-291.
Waibel, P.; Pomeroy, B.; Johnson, E. (1955) Effect of arasan-treated corn on laying
hens. Science 121:401-402.
Swanson, M.; Waibel, P.; Helbacka, N.; et al. (1956) Shell egg quality as affected by
arasanin the diet. Poultry Science 35:9295.
Grolleau, G.; Biaddi, F. (1966) Thiram and the reproduction of partridges. J. Appl.
Ecol. 3:250-251.
Magos, L. (1972) Relevancy of bivalent sulphur excretion to carbon disulphide
exposure in different metabolic conditions. Brit. J. Industr. Med. 29:90-94.
Solel, Z.; Edgington, L. (1973) Transarticular movement of fungicides. Phytopathology
63:505-510.
Elespuru, R; Lijinsky, W. (1973) The formation of carcinogenic nitroso compounds
from nitrite and some types of agricultural chemicals. Fd. Cosmet. Toxicol. 11(5):807-
817.
Mamalyga, V.; Kulik, M.; Logvinenko, V. (1974) Indutsirovannye khlorofil'nye
mutatsii u yarovoi tverdoi pshenitsy. Dokl. Akad. Nauk SSSR 215(1):211-213.
Agnihotri, V. (1974) Thiram induced changes in soil microflora, their physiological
activity & control of damping-off in chillies (Capsicum annum). Indian Journal of
Experimental Biology 12(l):85-88.
Wainwright, M.; Pugh, G. (1975) Changes in the free amino acid content of soil
following treatment with fungicides. Soil Biol. Biochem. 7(1): 1-4.
Griffaton, G.; Faudemay, F.; Rozen, R; et al. (1975) Metabolisme energetique du foie
chez des rats recevant un regime contamine par des dithiocarbamates. Ann. Nutr. Alim.
29(2):103-116.
167
-------
00143838
Kumarasamy, R; Raghu, K. (1976) Copper dimethyldithiocarbamate, a degradation
product of thiram in soil. Chemosphere 5(2): 107112.
00143839 Hofmann, W. (1975) Alcohol aversion from thiuram derivatives. 48: 23.
00143840 Hoflich, G. (1977) Einsatz von bioziden zur beeinflussung der bodenmikroflora und
deren umsetzungen 3. Mitteilung: Wechselbeziehungen zwischen veraenderten
mikroorganismenpopulationen und dem abbau von grundungungspflanzen im vergleich
zum strohabbau [The effect of biocides on the microflora of soils and their degradation
3. Interactions between modified populations of micro-organisms and the
decomposition of plants for green-manure in comparison to the decomposition of straw.
Zbl. Bakt. 132(2): 148154.
00143841 Wainwright, M.; Sowden, F. (1977) Influence of fungicide treatment on CaC12
phosphorus and phosphate-solubilizing micro-organisms in soil. Plant and Soil 48:335-
345.
00143842 Short, R.; Winston, J.; Minor, J.; et al. (1977) Toxicity of [inert ingredient] in mice and
rats and its alteration by various treatments. Journal of Toxicology and Environmental
Health 3:
913-921.
00143843 Antiserov, S.; Zhavoronkov, N. (1978) Effect on TMTD on the reproductive function of
animals. Vses. Inst. Eksp. Vet. Moscow, USSR (Veterinariya, Moscow) 2:70-2.
Abstract from an unknown source. 1 p.
00143844 Apol, A.; Thoburn, T. (1977) Health Hazard Evaluation Determination Composite
Report on Thiram 75-Thiram-352. National Institute for Occupational Safety and
Health, Cincinnati, OH. Available from the National Technical Information Service,
PB-273-729. 64 p.
00143845 Thiram Task Force (19??) Cross sensitization in drug dermatitis. Abstract from
unknown source. 1 p.
00143846 Vasilos, A.; Anisimova, L.; Todorova, E.; et al. (1978) Reproduktivnaya funktsiya krys
pri ostri i khronicheskoi intoksikatsii tetra metil uramidulfifidom [The reproductive
function of
rats in acute and chronic intoxication with thiram]. Gig. Sanit 43 (6):37-40. Abstract in
Toxicology and Pharmacology p. 30.
00143847 Chinn, S. (1973) Effect of eight fungicides on microbial activities in soil as measured by
abioassay method. Can. J. Microbiol 19:771-777.
00143848 Kada, T. (1974) Screening of pesticides for DNA interactions by "recassay" and
mutagenesis testing, and frameshift mutagens detected. Mutation Research 26:243-248.
168
-------
00143849
00143850
00143851
00143852
00143853
00143854
00143857
00143858
00143859
00143860
00143861
00143862
00143863
Munnecke, D.; Michail, K. (1967) Thiram persistence in soil and control of damping-
off caused by Pythium ultimum. Phytopathology 57:969-971.
Thiram Task Force (19??) [Thiram toxicology]. Compilation of abstracts from Chem.
Abs. 4 p.
Lowy, R.; Griffaton, G.; Dupuy,F.; et al. (1980) Dietary no-effect level of a
dithiocarbamate fungicide, thiram, evaluated from measurement data on rats. I. Choice
of the model of the dose-response relationship. Journal of Toxicology and
Environmental Health 6:403-419.
Olson, D.; Christensen, G. (1980) Effects of water pollutants and other chemicals on
fish acetylcholinesterase (in vitro). Environmental Research 21:327-335.
Zemaitis, M.; Greene, F. (1979) In vivo and in vitro effects of thiuram disulfides and
dithiocarbamates on hepatic microsomal drug metabolism in the rat. Toxicology and
Applied Pharmacology 48:343-350.
Quinot, E.; Moncelon, B.; Millard, M. (1978) Substances toxiques dans l'air: Essai de
determination d'une valeur limite calculee d'exposition. Cahiers de Notes
Decumentaires 93:547-565.
US National Library of Medicine (19??) [Literature Search (Toxline) for Data on
Thiram], Unpublished study. 10 p.
Information Retrieval Ltd. (19??) [Literature Search of Toxicological Abstracts for Data
on Thiram], Unpublished study. 8 p.
Markkula, M.; Rimpilaeinen, M.; Tiittanen, K. (1979) Harmfulness of soil treatment
with some fungicides and insecticides to the biological control agent Aphidoletes
aphidimyza (rond.) (dipt., cecidomyiidae). Annales Agriculturalae Fenniae 18:168-170.
Tewari, S.; Singh, R. (1979) Thin-layer chromatographic technique for the separation
and identification of carbamate pesticides in post mortem material. Journal of
Chromatography 172:528-530.
Webb, P.; Gibbs, S.; Mathias, C.; et al. (1979) Disulfiram hypersensitivity and rubber
contact dermatitis. JAMA 241(19):20.
Smithsonian Science Information Exchange (19??) [Literature Search for Data on
Thiram], Unpublished study. 8 p.
US National Technical Information System (19??) [Literature Search for Data on
Thiram], 4 p.
169
-------
00143864
00143865
00143866
00143867
00143868
00143869
00143870
00143872
00143873
00143874
00143875
Apol, A.; Thoburn, T. (1976) Health Hazard Evaluation/Toxicity Determination Report:
Supplement to Composite Report on Thiram for HHE-75-137-354, The Hoedads,
Eugene, Oregon. Prepared by National Institute for Occupational Safety and Health;
available from National Technical Information Service, PB-269-137.
10 p.
Apol, A.; Thoburn, T. (1976) Health Hazard Evaluation/Toxicity Determination Report:
Supplement to Composite Report on Thiram for HHE-75-140-357, Webfoot
Reforestation, Pleasant Hill, OR. Prepared by National Institute for Safety and Health;
available from National Technical Information Service, PB-269-136. 10 p.
Apol, A.; Thoburn, T. (1976) Health Hazard Evaluation/Toxicity Determination Report:
Supplement to Composite Report on Thiram for HHE-75-123-358, Weyerhaeuser Co.,
Centralia, Washington. Prepared by National Institute for Occupational Safety and
Health; available from National Technical Information Service, PB-269131. 18 p.
Apol, A.; Thoburn, T. (1976) Health Hazard Evaluation/Toxicity Determination Report
Supplement to Composite Report on Thiram for HHE 75-132-355, Industrial Forestry
Association, Canby, Oregon. Prepared by National Inst, for Occupational Safety &
Health; available from National Technical Information Service, PB-269130. 13 p.
Apol, A.; Thoburn, T. (1976) Health Hazard Evaluation/Toxicity Determination
Supplement to Composite Report on Thiram for HHE-75188-353, Challenge
Reforestation, Inc., Falls City, Oregon. Prepared by National Inst, for Occupational
Safety & Health, available from National Technical Information Service, PB-269113.
10 p.
Pollution Abstracts, Div. Data Courier (19??) [Literature Search for Data on Thiram],
Unpublished study. 5 p.
Rubber and Plastic Research Association (19??) [Literature Search for Data on Thiram],
Unpublished study. 4 p.
Haeggstroem, B. (1978) Sweden acts on rubber chemical health hazards. European
Rubber Journal 160(6): 11 -65.
Smith, M.; Robert, C.; John, C.; et al. (1977) An improved low ammonia NR latex
concentrate. Elastomerics 109(11):35-39.
National Library of Medicine (1980) [Literature Search for Data on Thiram: Medlars
II]. Unpublished study. 67 p.
Andrews, A.; Fornwald, J.; Lijinsky, W. (1980) Nitrosation and mutagenicity of some
amine drugs. Toxicology and Applied Pharmacology 52:237-244.
170
-------
00143876
00143877
00143878
00143879
00144009
00145105
00145106
00145325
00145326
00145327
00145328
00145598
Hedenstedt, A.; Rannug, U.; Ramel, C.; et al. (1979) Mutagenicity and metabolism
studies on 12 thiuram and dithiocarbamate compounds used as accelerators in the
Swedish rubber industry. Mutation Research 68:313-325.
Zdzienicka, M.; Zielenska, M.; Tudek, B.; et al. (1979) Mutagenic activity of thiram in
Ames tester strains of Salmonella typhimurium. Mutat. Res. 68(1):9-13. Abstract from
unknown
source, p. 104.
Fishbein, L. (1976) Environmental health aspects of fungicides. I. Dithiocarbamates.
Journal of Toxicology and Environmental Health 1:713-735.
Hodgson, J.; Lee, C. (1977) Cytotoxicity studies on dithiocarbamate fungicides.
Toxicology and Applied Pharmacology 40:19-22.
Johnston, R; Bayer, R. (1959) Letter sent to E. Feenstra dated Feb 27, 1959:
Acti-Dione-Thirma (sic) Fungicide; Res. #12,835: Skin irritation in rabbits: Reference
No. 4169-RLJ-129-107. 2 p.
Busch, B. (1984) Acute Inhalation Toxicity of UBI2359 in SpragueDawley Rats:
FDRL Study No. 8253. Unpublished study prepared by Food & Drug Research
Laboratories, Inc. 54 p.
Reagan, E. (1984) Primary Eye Irritation Study of UBI 2359 in New Zealand White
Rabbits: FDRL Study No. 8253A. Unpublished study prepared by Food & Drug
Research Laboratories, Inc. 19 p.
Wolfe, G. (1984) Acute Oral Toxicity Study in Rats: Agrosol Pour-on Systemic
Soybean Seed Treatment Fungicide: Final Report: Project No. 2278-104. Unpublished
study prepared by Chipman Inc. 9 p.
Wolfe, G. (1984) Acute Dermal Toxicity Study in Rabbits: Agrosol Pour-on Systemic
Soybean Seed Treatment Fungicide: Final Report: Project No. 2278-105. Unpublished
study prepared by Chipman Inc. 12 p.
Wolfe, G. (1984) Primary Dermal Irritation Study in Rabbits: Agrosol Pour-on
Systemic Soybean Seed Treatment Fungicide: Final Report: Project No. 2278-107.
Unpublished study prepared by Chipman Inc. 8 p.
Wolfe, G. (1984) Primary Eye Irritation Study in Rabbits: Agrosol Pour-on Systemic
Soybean Seed Treatment Fungicide: Final Report: Project No. 2278-106. Unpublished
study prepared by Chipman Inc. 14 p.
Bochow, H; Luc, L.; Sung, P. (1971) Untersuchungen ueber die entwicklung einer
171
-------
toleranz bei phytopathogenen pilzen gegenueber systemfungiziden. Acta
Phytopathologica Academiae Scientiarum Hungaricae 6(l-4):399.
00145794 Thiram Task Force (1985) Proposed Protocol of Thiram Plant Metabolism.
Unpublished study prepared by Uniroyal Chemical. 3 p.
00145796 Lemal, R. (1983) TMTD: Determination of Rate of Hydrolysis as a Function of pH.
Unpublished study prepared by UCB Chemicals Corp. 7 p.
00145797 Lemal, R. (1983) TMTD: Determination of Octanol/Water Partition Coefficient.
Unpublished study prepared by UCB Chemicals Corp. 6 p.
00145798 Debets, I. (1985) Evaluation of the Mutagenicity Activity of Thiram in an in vitro
Mammalian Cell Gene Mutation Test with V79 Chinese Hamster Cells (with
Independent Repeat). Unpublished study prepared by Notox v.o.f. 6 p.
00145799 Debets, I. (1985) Evaluation of the Ability of Thiram to Induce Chromosome
Aberrations in Cultured Chinese Hamster Ovary (CHO) Cells (Including Multiple
Fixation Times). Unpublished study prepared by Notox v.o.f. 4 p.
00145800 Weterings, P. (1985) Evaluation of DNA Repair Inducing Ability of Thiram in a
Primary Culture of Rat Hepatocytes. Unpublished study prepared by Notox v.of.
5 p.
00146050 Reagan, E. (1984) Acute Oral LD50 Study of UBI2359 in Sprague-Dawley Rats:
FDRL Study No. 8253A. Unpublished study prepared by Food & Drug Research
Laboratories, Inc. 82 p.
00146051 Reagan, E. (1984) Acute Dermal Toxicity Study of UBI 2359 in New Zealand White
Rabbits: FDRL Study No. 8253A. Unpublished study prepared by Food & Drug
Research Laboratories, Inc. 18 p.
00146052 Reagan, E. (1984) Dermal Sensitization Study of UBI 2359 in Albino Guinea Pigs
(Modified Buehler Test): FDRL Study No. 8253. Unpublished study prepared by Food
6 Drug Research Laboratories, Inc. 41 p.
00146058 Reagan, E. (1984) Primary Dermal Irritation Study of UBI 2359 in New Zealand White
Rabbits: FDRL Study No. 8253A. Unpublished study prepared by Food & Drug
Research Laboratories, Inc. 18 p.
00147097 Van Leeuwen, C. (19??) The toxicological consequences of the use of
dialkyldithiocarbamates for some softwater organisms. A translation of an untitled
article from an unknown publication.
00147098 Espeldooren, A. (1981) [Toxicity Test with Thiram in 25 Daphnia magna].
Unpublished translation of study prepared by UCB. 4 p.
172
-------
00147099
00147100
00147101
00147102
00148170
00148171
00148178
00148179
00148180
00148181
00148182
00148414
00148415
Thouin, M. (1985) Evaluation of the Acute Dermal Toxicity of TMTD Technical in the
Rabbit: NOTOX 0113/211. Unpublished study prepared by NOTOX v.o.f. lip.
Mulder, D. (1985) Assessment of Eye Irritation by TMTD Technnical (sic) in the
Rabbit: NOTOX 0113/174. Unpublished study prepared by NOTOX v.o.f. 12 p.
Weterings, P. (1985) Assessment of Primary Skin Irritation by TMTD Technical in the
Rabbit: NOTOX 0113/173. Unpublished study prepared by NOTOX v.o.f. lip.
Danschutter, J. (1985) TMTD Technical: Solubility: Report WL No. 04/85.
Unpublished study prepared by UCB. 3 p.
UCB Chemicals Corp. (1985) Product Chemistry: [Thiram Technical], Unpublished
compilation. 78 p.
Biological Federal Office for Agriculture and Forestry Management (1973) Measure of
Leaching Property of Pesticides: Memorandum No. 37. Unpublished translation of a
protocol prepared in conjunction with the "Soil and Water" Committee of the Industrial
Organization of Crop Pesticides and the Institution for Water, Soil and Clean Air Act of
the Office for Federal Health. 5 p.
Bayer AG (1977) Pesticide Residue in Groundwater: [Pomarsol Forte 80 WP]: Study
No. 8800/77. Unpublished translation. 1 p.
Bayer AG (1977) Pesticide Residue in Groundwater: [Pomarsol Forte 80 WP]: Study
No. 8801/77. Unpublished translation. 1 p.
Bayer AG (1974) Pesticide Residue in Groundwater: [Pomarsol Forte]: Study No.
8803/74. Unpublished translation. 1 p.
Bayer AG (1974) Pesticide Residue in Groundwater: [Pomarsol Forte]: Study No.
8804/74. Unpublished translation. 1 p.
Bayer AG (1974) Pesticide Residue in Groundwater: [Pomarsol Forte]: Study No.
8805/74. Unpublished translation. 1 p.
Lemal, R. (1983) Note L.P.C.D. No. 80: TMTD [(Tetramethylthiuram Disulfide)]:
Determination of Rate of Hydrolysis as a Function of pH. Unpublished translation of
Note L.P.C.D. No. 80: DTMT: Determination de la Vitesse d'Hydrolyse a Differents pH
prepared by UCB. 7 p.
Prochimie, International, Inc. (1985) [Product Chemistry Data of Thiram Technical],
Unpublished compilation. 69 p.
173
-------
00148439
Virginia Chem, Inc. (1985) Thiram Re-registration ... Product Chemistry. Unpublished
compilation. 73 p.
00148487 UCB Chemicals Corp. (1985) Product Chemistry [of] Thiram. Unpublished
compilation. 14 p.
00148488 UCB Chemicals Corp. (19??) Comparison of Assessment Methods NEN 6501 (Dutch)
and ASTM E 729-80. Unpublished study. 4 p.
00148571 Hughes, T. (1984) Acute Oral Median Lethal Dosage Study in Rats; Acute Dermal
Toxicity Screen in Rabbits; Primary Skin Irritation Study in Rabbits; Primary Eye
Irritation Study in Rabbits of Seed Treatment 4LB Thiram with Red Dye: Hill Top
Research Project No. 84-0681-21. Unpublished study prepared by Hill Top Research,
Inc. 33 p.
00148572 Solmecke, B.; Kimmerle, G. (1969) [Inert Chemical] Toxicological Study [on
Laboratory Mammals and Humans]: Report No. 1635. Unpublished study prepared by
Bayer AG. 8 p.
00148573 Bathe, R. (1983) 29-day Oral Toxicity Feeding Study (Range-finding) with Repetitive
Administration of [Inert Chemical] to Beagle Dogs: Project 009347. Unpublished study
prepared by Research & Consulting Co., Ltd. 108 p.
00148574 Mihail, F.; Nash, G. (1983) [Inert Chemical] Subchronic Toxicological Study with Rats:
Test with Stomach Tube Administration over 3 Months: Report No. 11852.
Unpublished study prepared by Bayer AG. 165 p.
00148575 Bathe, R. (1984) 6-month Oral (Feeding) Toxicity Study with [Inert Chemical] in
Beagle Dogs: Project 009358. Unpublished study prepared by Research & Consulting
Co. AG. 300 p.
00148909 R. T. Vanderbilt Co. Inc. (1983) [Product Chemistry Data for Thiram Products],
Unpublished compilation. 6 p.
00149192 Lemal, R. (1983) TMTD: Determination of Rate of Hydrolysis as a Function of pH:
Aff. 2.24.007: Note L.P.C.D. No. 80. Unpublished translation of study prepared by
UCB, Drogenbos Laboratories. 7 p.
00149379 UCB Chemicals Corp. (1985) Thiram Technical (Tetramethylthiuram Disulphide):
[Product Chemistry Data], Unpublished compilation. 62 p.
00150506 Pennwalt Corp. (1985) Thiram Technical: Product Chemistry. Unpublished study. 5 p.
00150607 McArdle, T. (1985) Product Chemistry: Thiram Moly Fl. Unpublished compilation
prepared by Trace Chemicals, Inc. 24 p.
174
-------
00151213
00151609
00151610
00151611
00152336
00152514
00152556
00152557
00152838
00152839
00153068
00153224
00153225
00153226
Pennwalt Corp. (1984) Resubmission of Data References for Thiram: [Abstracts of
Toxicology Data on Thiram, 1965 through 1977], Unpublished study. 132 p.
Van Beylen, M. (1985) Determination of Dissociation Constant of Tetramethylthiuram
Disulfide: Report No. 722/85/MVB/BH. Unpublished study prepared by Katholieke
Universiteit Leuven. 2 p.
Giurgea, M. (1978) Rat Teratology: TMTD. Unpublished study prepared by U.C.B
Chemicals Corp. 62 p.
Van Breeman, M. (1985) Assessment of the Biodegradability of TMTD Technical in
the Closed Bottle Test: NOTOX 0113/RB/CBT. Unpublished study prepared by Notox
V.O.F.18 p.
Brune, H.; Mohr, U. (1980) Toxicological Investigation of Thiram in the Chronic
Feeding Study with NMRI Mice: Report No.: R 1791. Unpublished study prepared by
Advisory Board for Preventive Medicine and Environmental Protection, Ltd. 181 p.
Trace Chemicals, Inc. (1985) Product Chemistry: Thiram Moly Fl: Physical and
Chemical Characteristics. Unpublished compilation. 16 p.
Debets, F. (1985) Evaluation of the Acute Inhalation Toxicity of TMTD Technical in
the Rat: NOTOX 0113/232. Unpublished study prepared by Notox V. O. F. 17 p.
Thiram Task Force (1985) [Product Chemistry Data: TMTD], Unpublished
compilation. 6 p.
Valle-Herrera, V. (1984) [Efficacy Data]: Repel #3 Rat and Mouse Repellent.
Unpublished compilation prepared by Colegio de Ingenieros Quimicos de Jalisco, A. C.
5 p.
Alcor Products Corp. (1985) Alcor's Rat and Mouse Repellent: Chemistry: [Product
Chemistry Data], Unpublished compilation. 13 p.
Weterings, P. (1985) Assessment of the Skin Sensitisation Potential of TMTD
Technical inthe Guinea-pig (Split Adjuvant Test): Study No. 0174/263. Unpublished
study prepared by Notox v.o.f, Hambakenwetering 31. 11 p.
Myers, R. (1985) Rootone: Acute Toxicity and Irritancy Study: Project Report 48-129.
Unpublished study prepared by Union Carbide Corp. 19 p.
Myers, R; Christopher, S. (1985) Rootone: Dermal Sensitization Study in the Guinea
Pig: Project Report 48-151. Unpublished study prepared by Union Carbide Corp. 18 p.
Mayhew, D. (1985) Four Hour Acute Dust Inhalation Toxicity Study in Rats of
Rootone: Study No. 420-2266. Unpublished study prepared by American Biogenics
175
-------
Corp. 16 p.
00153548 Thouin, M. (1985) Evaluation of the Acute Oral Toxicity of TMTD Technical in the
Rat: Study No. 0174/238. Unpublished study prepared by Notox v.o.f
Hambakenwetering 31. 19 p.
00153914 Alcor Products Inc. (1984) Repel for Rats and Mice: [Product Chemistry Data],
Unpublished study. 17 p.
00154264 Van Leeuwen, C. (1985) The Toxicological Consequences of the Use of
Dialkyldithiocarbamates for Some Sofhvater Organisms. Unpublished translation of
journal article with related data prepared by RIZA Ecotoxicology Laboratory. 14 p.
00154385 Virginia Chem Inc. (1982) [Product Chemistry and Residue Data for
Tetramethylthiuram Disulfide], Unpublished compilation. 19 p.
00154386 E. I. du Pont de Nemours & Co. Inc. Agric. (1977) General Chemistry Data on Du Pont
Thiram Technical. Unpublished study. 17 p.
00154387 E. I. du Pont de Nemours & Co. Inc. Agric. (1954) Thiram in Crop Residues.
Unpublished study. 5 p.
00154398 Palmer, J.; Schlinke, J. (19??) Preliminary Toxicological Evaluations of Six Pesticide
Compounds in Cattle, Sheep, and Chickens. Unpublished study prepared by U.S.
Department of Agriculture. 9 p.
00154661 Virginia Chem Inc. (1985) [Product Chemistry Data on Thiram], Unpublished
compilation. 22 p.
00154758 Koeppe, M. (1985) Crop Rotation Study with [Carbon-14]-DPX-Y6202 in the
Greenhouse: Doc. No. AMR-218-84, Revision 1. Unpublished study prepared by E. I.
du Pont de Nemours & Co., Inc. 27 p.
00154984 Klisenko, M.; Vekshtein, M. (1971) Kinetics of the hydrolysis of metal complexes of
dialkyldithiocarbamic and ethylenebisdithiocarbamic acids in their dependence on the
pH of the medium, and identification of their transformation products. J. Gen. Chem. of
the U S S R. 41(5): 1125-1130.
00155063 Klisenko, M.; Vekshtein, M. (1971) Kinetics of hydrolysis of metal derivatives of
dialkyland ethylenebis(dithiocarbamic acids) as a function of pH and identification of
their reaction products. Journal of General Chem. of the U.S.S.R. 41(5): 1125-1130.
Abstracted in C.A. v. 75, NO. 87761U.
00155724 Alcor Products Corporation (1985) Repel Rat and Mouse Repellent... Chemistry
Addendum. Unpublished compilation. 12 p.
176
-------
00156064 Weterings, P. (1985) Evaluation of the DNA Repair Inducing Ability of TMTD
Technical in a Primary Culture of Rat Hepatocytes: NOTOX 0174/ER156. Unpublished
study prepared by Notox v.o.f. 35 p.
00156065
00157532
Debets, F. (1985) Evaluation of the Ability of TMTD Technical To Induce
Chromosome Aberrations in Cultured Chinese Hamster Ovary (CHO) Cells, Using
Multiple Fixation Times: NOTOX 0174/EC108. Unpublished study prepared by Notox
v.o.f. 21 p.
R.T. Vanderbilt Co., Inc. (1986) Thiram: Vancide TM: Tetramethyl Thiram Sulfide:
[Product Chemistry Data], Unpublished compilation. 26 p.
00157726 Derr, H. (1959) What's new in bird repellants for direct seeding Forests & People (4):1-
2.
00158111 Freeman, T. (1959) Letter sent to G. Swank dated Oct 16, 1959: [Efficacy: fungicide
testing program: Gab-5], Prepared by University of Florida, Agri. Exper. Stations. 3 p.
00158373 Liggett, M.; Parcell, B. (1986) Acti-Dione Thiram Formulation: Irritant Effects on the
Rabbit Eye: HRC Report No. 851150D/FSB 219/SE. Unpublished study prepared by
Huntingdon Research Centre Ltd. 9 p.
00158374 Liggett, M.; Parcell, B. (1985) Acti-Dione Thiram Formulation: Irritant Effects on
Rabbit Skin:HRC Report No. 851152D/FSB 218/SE. Unpublished study prepared by
Huntingdon Research Centre Ltd. 7 p.
00158460 Deenihan, M. (1985) Acute Oral Toxicity: Acute Dermal Toxicity: Primary Skin
Irritation: Primary Eye Irritation: NVP Report No. X5H052G. Unpublished study
prepared by Northview Pacific Labs., Inc. 26 p.
00158665 Warren, J.; Drury, P.; Connor, S. (1986) Determination of Adsorption/Desorption
Constants of [Carbon- 14]-Thiram: ABC Final Report #33573. Unpublished study
prepared by Analytical BioChemistry Laboratories, Inc. 334 p.
00159398 Bonide Chemical Co., Inc. (1986) Product Chemistry Data: Rabbit and Deer Repellent
Concentrate. Unpublished compilation. 20 p.
00159581 Kynoch, S.; Smith, P. (1986) Acti-Dione Thiram Formulation: Delayed Contact
Hypersensitivity in the Guinea-pig: Study No. TOX 85089: 851334D/FSB 220/SS.
Unpublishedstudy prepared by Huntingdon Research Centre. 17 p.
00159690 Borderland Products Inc. (1984) [Efficacy Data Avian Repellency Studies Using
Methiocarb, Thiram, and Bayer Compounds], Unpublished compilation. 35 p.
00160279 Peachey, R. (1981) Skin hazards in farming. British Journal of Dermatology
105(21):45-50.
177
-------
00160621 Debets, F.; Enninga, I. (1986) Evaluation of the Mutagenic Activity of TMTD
Technical in an in vitro Mammalian Cell Gene Mutation Test with V79 Chinese
Hamster Cells: Study No. NOTOX 0174/EV 1. Unpublished study prepared by Notox
V.O.F. 52 p.
00160821 Greenough, R.; McDonald, P. (1986) Acti Dione Thiram Formulation: Acute Inhalation
Toxicity Study in Rats: IRI Project No. 632541: Report No. 3457. Unpublished study
prepared by Inveresk Research International. 33 p.
00161985 Gustafson, Inc. (1986) Product Chemistry of Technical Thiram: Overall Summary of
Product Composition and Manufacturing Process Information. Unpublished
compilation. 112 p.
00162015 UCB Chemicals Corp. (1986) Validation of Analytical Method: Thiram Technical.
Unpublished compilation, lip.
00162142 Harned, W.; Tortora, N. (1986) Uptake and Distribution of [Carbonl4] Thiram in
Cotton, Soybean and Wheat: Project No. 8565-A. Unpublished study prepared by
Uniroyal Chemical. 25 p.
00162602 O M Scott & Sons Co. (1986) Product Chemistry to Support Proturf Fluid Fungicide
m. Unpublished compilation. 34 p.
00162603 Glaza, S. (1986) Acute Oral Toxicity Study in Rats Method, Summary, Pathology
[Using Proturf Fluid Fungicide HI]: Final Report: Study No. 60403811. Unpublished
study prepared by Hazleton Laboratories America, Inc. 29 p.
00162604 Glaza, S. (1986) Acute Dermal Toxicity Study in Rabbits Method, Summary, Pathology
[Using Proturf Fluid Fungicide HI]: Study No. 60403812. Unpublished study prepared
by Hazleton Laboratories America, Inc. 22 p.
00162605 Glaza, S. (1986) Primary Eye Irritation Study in Rabbits Method, Summary [Using
Proturf
Fluid Fungicide HI]: Final Report: Study No. 60403810. Unpublished study prepared by
Hazleton Laboratories America, Inc. 23 p.
00162606 Glaza, S. (1986) Primary Dermal Irritation Study in Rabbits Method, Summary [Using
Prototurf Fluid Fungicide HI]: Study No. 60403813. Unpublished study prepared by
Hazleton Laboratories America, Inc. 17 p.
00162607 Glaza, S. (1986) Dermal Sensitization Study in Guinea Pigs (Closed Patch Technical
Method, Summary [Using Proturf Fluid Fungicide ID]: Final Report: Study No.
60403814. Unpublished study prepared by Hazleton Laboratories America, Inc.
27 p.
00162909 Taylor, W. (1986) Letter sent to H. Jacoby dated Aug 6, 1986: Data call-in Thiram ....
178
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Prepared by Vanderbilt Co., Inc. 20 p.
00163328 Hughes, T. (1986) Delayed Contact Hypersensitivity Study in Guinea Pigs of: Thiram
Flowable Seed Treater 3.8#/Gal: (Undyed): Project No. 86-0321-21. Unpublished study
prepared by Hill Top Research, Inc. 13 p.
00163330 Hughes, T. (1986) Delayed Contact Hypersensitivity Study in Guinea Pigs of: Thiram
Dyed Flowable Seed Treater 3.8#/Gal.: Project No. 86-0320-21. Unpublished study
prepared by Hill
Top Research Inc. 15 p.
00163331 Fermenta Animal Health Co. (1986) Grounds for Support of the Exemption from
Tolerance of [Inert Ingredient], Unpublished compilation. 9 p.
00164662 Husson, R. (1986) Letter sent to J. Rockwell dated Sept 17, 1986: [Data requested to
complete review of 48 hour LC50 study on Daphnia magna]. Prepared by UCB Societe
Anonyme. 3 p.
00165337 Uniroyal Chemical Co., Inc. (1984) The Name, Chemical Identity and Composition of
the Pesticide Chemical: [Vitavax-200 Flowable Fungicide], Unpublished compilation,
lip.
00165338 Uniroyal Chemical Co., Inc. (1983) The Results of the Amount of Residue Remaining:
[Vitavax in Safflower Seed], Unpublished compilation. 15 p.
00165512 Gustafson, Inc. (1986) Product Chemistry Data: Gustafson RTU-Vitavax-Thiram Seed
Protectant Fungicide. Unpublished compilation. 16 p.
05001190 Helling, C.S.; Dennison, D.G.; Kaufman, D.D. (1974) Fungicide movement in soils.
Phytopathology 64(8): 1091-1100.
05001322 King, C.C. (1959) The effects of fungicides. Gleanings in Bee Culture 87:678-681.
05001377 Williams, W.A.; Harwood, L.H.; Hills, F.J. (1960) Incompatibility of seed treatment
fungicides and seed-applied legume inoculum observed on field-grown subterranean
clover. Agronomy Journal 52(6):363-365.
05001433 Jacks, H. (1951) Soil disinfection: XI_ Control of foot-rot ( Phytophthora cryptogea P&
L) of tomatoes. New Zealand Journal of Science and Technology 33A(4):71-75.
05001513 Sleeth,B. (1946) The effect of fungicidal seed treatments on guayule seeding
emergence. Phytopathology 36:999-1010.
05001546 Leukel, R.W. (1952) Cooperative tests with fungicides for smut control in wheat and
oats in 1952. Plant Disease Reporter 36(11):428-433.
179
-------
05001554 Wallen, V.R. (1953) Treatment of vegetable seed for improved emergence. Plant
Disease Reporter 37(12):620-622.
05001558 Leukel, R.W.; Webster, O.J.; Porter, R.H. (1954) Sorghum seed-treatment tests in
1954. Plant Disease Reporter 38(11):769-770.
05001563 Harris, H.B.; Luttrell, E.S. (1955) Grain sorghum seed treatment tests and diseases in
Georgia for 1954. Plant Disease Reporter 39(4):329-331.
05001564 Daines, RH. (1955) Sweetpotato scurf control studies in New Jersey, 1942-1952. Plant
Disease Reporter 39(10):739-745.
05001572 Miller, P.M.; Stoddard, E.M. (1956) Field control of grey mold of strawberries. Plant
Disease Reporter 40(9):788-789.
05001576 Rich, S.; Taylor, G.S. (1957) Cottonseed oil formulations of organic fungicides for
tobacco. Plant Disease Reporter 41(5):465-467.
05001603 Stall, R.E. (1964) Fungicidal control of Botrytis cinerea Pers_ ex Fr_ on tomato. Pages
242-244, In Proceedings—Florida State Horticultural Society. Vol. 77. Lake Alfred,
Fla.:Florida State Horticultural Society. (Florida Agricultural Experiment Station
Journal series No. 1986)
05001628 Hamdi, Y.A.; Moharram, A. A.; Lofti, M. (1974) Effect of certain fungicides on some
rhizobia-legume-symbiotic systems. Zentralblatt fuer Bakteriologie, Parasitenkunde,
Infektionskrankheiten und Hygiene, Abteilung II 129(3/4):363-368.
05001643 Jacks, H; Brook, P.J. (1954) Control of black spot of apples. New Zealand Journal of
Science and Technology 36A:78-89.
05001655 Odeyemi, O. (1976) Resistance of Rhizobium to Thiram, Spergon, and Phygon:
Doctoral Thesis. Ithaca, N.Y.: Cornell University. (Available from: University
Microfilms International, Ann Arbor, Michigan; order no. 77-18,187)
05001658 Guba, E.F. (1954) Control of Fusicoccum peach canker. Pages 69-70, In Massachusetts
Fruit Growers' Association. Report of the Annual Meeting, No. 60. North Amherst,
Mass.: Massachusetts Fruit Growers' Association.
05001699 Horn, N.L. (1961) Control of Botrytis rot of strawberries. Plant Disease Reporter
45(10):818-822.
05001773 Ruhloff, M.; Burton, J.C. (1951) Compatibility of rhizobia with seed protectants. Soil
Science 72:283-290.
05002504 Afifi, N.M.; Moharram, A.A.; Hamdi, Y.A.; Abd-El-Malek, Y.A. (1969) Sensitivity of
Rhizobium species to certain fungicides. Archiv fuer Mikrobiologie 66(2): 121-128.
180
-------
05003675
Mills, L.J.; Kotze, J.M. (1978) Control of stem rust of wheat with systemic fungicides.
Phytophylactica 10(1): 17-20.
05003947 Curley, R.L.; Burton, J.C. (1975) Compatibility of Rhizobium japonicum with
chemical seed protectants. Agronomy Journal 67(6):807-808.
05004330 Kecskes, M.; Vincent, J.M. (1969) Nehany fungicid hatasa a Rhizobium
leguminosarum sp-re_: U_ Fenykamras es uveghazi vizsgalatok_ The effect of some
fungicides on Rhizobium leguminosarum _: H_ Light room and glasshouse
investigations_ Agrokemia es Talajtan. Agrochemistry and Soil Science. 18(3/4):461-
472.
05009387 Seiler, J.P. (1977) Nitrosation in vitro and in vivo by sodium nitrite, and mutagenicity of
nitrogenous pesticides. Mutation Research 48(5):225-236.
05016261 Ruschel, A.P.; Da Costa, W.F. (1966) Fixacao simbiotica de nitrogenio atmosferico em
feijao (Phaseolus vulgaris LJ_ m_ Influencia de alguns inseticidas e fungicidas_
Symbiotic fixing of atmospheric nitrogen in the French bean ( Phaseolus vulgaris LJ_
m_ Effect of some insecticides and fungicides_ Pesquisa Agropecuaria Brasileira.
Brazilian Agricultural and Veterinary Research. 1:147-149.
05020356 Hutber, G.N.; Rogers, L.J.; Smith, A.J. (1979) Influence of pesticides on the growth of
cyanobacteria. Zeitschrift fur Allgemeine Mikrobiologie 19(6):397-402.
40016900 California Dept. of Food and Agriculture (1985) Data Submitted to Fulfill the
Registration Requirements: Compound 1080. Compilation of 99 Studies.
40016989 Hornshaw, T.; Ringer, R. (1983) Effects of Compound 1080, o-cresol, and Thiram on
the Reproductive Performance of Mnk and/or Ferrets. Unpublished study prepared by
Mchigan State Univ., Dept. of Animal Science. 12 p.
40022000 California Dept. of Food and Agriculture (1986) Data Submitted to Fulfill the
Registration
Requirement: Compound 1080. Compilation of 36 studies.
40022008 Hornshaw, T.; Ringer, R.; Aulerich, R; et al. (1983) Determination of LC50 for
Compound 1080, o-Cresol, Thiram, and Aroclor 1254 in Mnk and/or Ferrets.
Unpublished study prepared by Mchigan State Univ., Dept. of Animal Sciences. 23 p.
40128600 Chas. H. Lilly Co. (1987) Submission of Product Chemistry Data for Lilly/Mller Bulb
Dust. Transmittal of 1 study.
40128601 Hewitt, M. (1987) Lilly/Mller Bulb Dust: Product Chemistry Data. Unpublished study
prepared by Chas. H. Lilly Co. lip.
40207900 International Paint (U.S.A.) Inc. (1987) Submission of Data in Response to Data Call In
181
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on Tributyltins Used in Antifouling Paints: Product Chemistry and Efficacy Studies.
Transmittal of 24 studies.
40207910 Ludgate, J. (1987) Product Chemistry for Registration Number 85: Wide Spectrum
Speedcote Antifouling Grey 3221], Unpublished compilation prepared by International
Paint Co., (USA) Inc. 3 p.
40216500 Thiram Task Force (1987) Submission of Data To Support the Registration of Thiram:
Toxicity and Residue Studies. Transmittal of 3 studies.
40216501 Maedgen, J.; Lain, D. (1987) Rat Acute Inhalation Toxicity: [Thiram Technical]:
Laboratory Project ID: 4730-87. Unpublished study prepared by Stillmeadow, Inc. 19 p.
40216502 Nowakowski, M. (1987) Identification of Metabolites in Cotton, Wheat and Soybean
Seedlings Grown from (Carbon 14)Thiram Treated Seeds: Uniroyal Project ID No.
8565-C. Unpublished study pre pared by Uniroyal Chemical Co., Inc. 47 p.
40216503 Tesh, J.; McAnulty, P.; Willoughby, C.; et al. (1987) Thiram: Effects of Oral
Administration Upon Pregnancy in the Rat-Preliminary Teratology Study: Laboratory
Project ID. 86/TRK001/704. Unpublished study prepared by Life Science Research. 39
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40224500 Gustafson, Inc. (1987) Submission of Product Chemistry Data for Gustafson Thiram
Technical. Transmittal of 1 study.
40224501 Riggs, A.; Brewer, A.; Van Veen, W. (1983) Product Chemistry Data: Gustafson
Thiram Technical: Project ID No. 87-012. Unpublished study prepared by Uniroyal,
Ltd. 39 p.
40239500 Gustafson Inc. (1987) Toxicological Data of Technical Thiram in the Chronic Feeding
Study with Mice. Transmittal of 1 study.
40239501 Brune, H.; Deutsch-Wenzel, R; Mohr, U.; et al. (1980) Toxicological Investigation of
Thiram in the Chronic Feeding study with NMRI Mice: Lab. Proj. ID R 1791.
Unpublished study
prepared by Advisory Board for Preventive Medicine and Environmental Protection,
Ltd. 1154 p.
40239600 Nelson Research & Development Co. (1987) Submission of Product Chemistry &
Toxicity Data To Support the Clearance of Inert Ingredient in Agricultural Pesticide
Products. Additional Data was Submitted by NOR-AM Chemical Co. Transmittal of 12
studies.
40239601 Vaidyanathan, R. (1987) [Inert Ingredient]-Chemistry, Unpublished compilation
prepared by Nelson Research & Development Co. 25 p.
182
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40239602 Gundersen, L. (1987) [Inert Ingredient]~Discussion: Relative Toxicity by Oral vs
Dermal Route. Unpublished study prepared by Nelson Research & Development Co. 5
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40239603 Killey, F. (1983) [Inert Ingredient] 6 Month Rat Dermal Toxicity Study: Laboratory
Project ID: 1228A-0294-1. Unpublished study prepared by Allergan Pharmaceuticals,
Inc. 482 p.
40239605 Dickie, B. (1985) [Inert Ingredient] 12 Month Monkey Dermal Toxicity Study: [Final
Report]: Laboratory Project ID: 6153-101. Unpublished study prepared by Hazleton
Laboratories America, Inc. 231 p.
40239607 Edwards, J.; Leeming, N; Masters, R; et al. (1984) [Inert Ingredient] Rabbit
Teratology Study: Lab Project ID: NLN 5/84650. Unpublished study prepared by
Huntingdon Research Centre. 68 p.
40239608 Oren, J. (1987) Overview and Summaries: Five (5) Mutagenicity Studies: [Using Inert
Ingredient], Unpublished compilation prepared by Nelson Research & Development
Co. 9 p.
40239609 Stankowski, L. (1985) CHO/HGPRT Mammalian Cell Forward Gene Mutation Assay:
Laboratory Project ID: PH 314-NR-001-85. Unpublished study prepared by Pharmakon
Research International, Inc. 41 p.
40239610 Barfknecht, T. (1985) Rat Hepatocyte Primary Culture/DNA Repair Test: [Inert
Ingredient]: Lab Project ID: PH 31 l-NR-001-85. Unpublished study prepared by
Pharmakon Research International, Inc. 76 p.
40239611 Sorg, R. (1985) Micronucleus Test (MNT) OECD: [Using Inert Ingredient]: Laboratory
ProjectID: PH 309A-NR-001-85. Unpublished study prepared by Pharmakon Research
International, Inc. 41 p.
40239612 Barfknecht, T. (1985) Ames Salmonella/Microsome Plate Test: [Inert Ingredient]:
Laboratory Project ID: PH 301-NR-001-85. Unpublished study prepared by Pharmakon
Research International, Inc. 30 p.
40239613 Zimmer, D.; Mazurek, J.; Bhuyan, B. (1979) 2. Mutagenicity: [Results of Animal
Studies Using Inert Ingredient], Unpublished compilation prepared by Upjohn Co.
7 p.
40294600 Micro Flo Co. (1987) Submission of Product Chemistry Data To Support the
Registration of Thiram 65WP. Transmittal of 1 study.
40294601 Tucker, D. (1987) 14 Month Storage Stability Study for Thiram 65WP: Laboratory
Project ID: MICRO-FLO THI65-EU-1. Unpublished study prepared by Chempax.
4 p.
183
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40444704
40495200
Micro Flo Co. (1987) Submission of Chemistry Data to Support the Registration for
Thiram 75WP. Transmittal of 1 study.
Tucker, D. (1987) 14 Month Storage Stability Study for Thiram 75WP: Lab. proj. ID
TH175-EU-1. Unpublished study prepared by Chempax. 4 p.
Mobay Corp. (1987) Submission of Exposure Data to Support the Registration of
Baytan. Transmittal of 3 studies.
Grey, W.; Marthre, D.; Rogers, S. (1983) Potential exposure of commercial seed-
treating applicators to the pesticides Carboxinthiram and Lindane. Bull. Environ.
Contam. Toxicol. 31:244-250.
Akzo Chemie Nederland (1987) Submission of Product Chemistry Data for Registration of Thiram
Technical. Transmittal of 3 studies.
Obuch, D. (1986) Thiram Technical-Dordrecht: Product Identity And Composition.
Unpublished study submitted by Akzo Chemie Nederland.
Obuch, D. (1986) Thiram Technical-Dordrecht: Analysis and Certification of Product Ingredients.
Unpublished study prepared by Akzo Chemie Nederland. 7 p.
Obuch, D. (1986) Thiram Technical-Dordrecht: Physical and Chemical Characteristics.
Unpublished study prepared by Akzo Chemie Nederland. 6 p.
Thiram Task Force c/o Gustafson Inc. (1987) Submission of Data To Support the
Reregistration of Thiram: Toxicology and Environmental Fate Studies. Transmittal of 4 studies.
Holbert, M. (1987) Acute Inhalation Toxicity in Rats: Laboratory Project No. 4730-87.
Unpublished study prepared by Stillmeadow, Inc. 39 p.
Tesh, J.; Ross, F.; Crisp, V. (1987) Thiram: Effects of Oral Administration Upon Pregnancy in the
Rabbit-Preliminary Teratology Study: Laboratory Project ID: 87/TRK003/122. Unpublished study
prepared by Life Science Research. 90 p.
Cranor, W. (1987) Determination of the Hydrolysis Rate of Carbon 14-Thiram: Laboratory Project
ID: 34030. Unpublished study prepared by Analytical Bio-Chemistry Laboraotries, Inc. 675 p.
Cranor, W. (1987) Determination of the Photolysis Rate of Carbon 14-Thiram: Laboratory Project
ID: 33571. Unpublished study prepared by ABC Laboraotries, Inc. 385 p.
Pennwalt Corp. (1988) Submission of Data in Response to EPA Product Chemistry and Residue
Chemistry Data Call-In for Ziram. Transmittal of 1 study.
184
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40510900 Thiram Task Force (1988) Submission of Mutagenicity Studies to Support the Registration for
Thiram. Transmittal of 2 studies.
40510901 Putman, D. (1987) Chromosome Aberrations in Chinese Hamster Ovary (CHO) Cells: Thiram:
Study No. T5558.337. Unpublished study prepared by Microbiological Associates, Inc. 94 p.
40510902 Putman, D. (1987) Micronucleus Cytogenetic Assay in Mice: Thiram: Final Report:
T5558.122. Unpublished study prepared by Microbiological Associates, Inc. 140 p.
40534100 Gustafson, Inc. (1988) Submission of Product Chemistry Data to Support the Reregistration of
Thiram. Transmittal of 1 study.
40534101 Tesh, J.; McAnulty, P.; Willoughby, C.; et al. (1988) Thiram: Teratology Study in the Rat:
87/TRK002/179. Unpublished study prepared by Life Science Research. 91 p.
40577300 Thiram Task Force (1988) Submission of Teratology Data to Support the Thiram
Registration Standard. Transmittal of 1 study.
40577301 Tesh, J.; Ross, F.; Crisp, V.; et al. (1987) Thiram: Teratology Study in the Rabbit:
87/TRK004/541. Unpublished study prepared by Life Science Research. 80 p.
40621500 The Chas. H. Lilly Co. (1988) Submission of Product Chemistry Data to Support the Registration
of Lilly/Miller Dog and Cat Repellent. Transmittal of 1 study.
40621501 Klettke, M. (1988) Lilly/Miller Dog and Cat Repellent: Product Chemistry Data. Unpublished
study prepared by The Chas. H. Lilly Co. 36 p.
40712000 Gustafson Inc. (1988) Product Chemistry Data submitted for Vitaflo280 Flowable Fungicide
registration. Transmittal of 1 study.
40712001 Collins, R. (1988) Product Chemistry Data: Gustafson Vitaflo-280 Flowable Fungicide: Project
ID. 1506-193-REC. Unpublished study prepared by Uniroyal Chemical Co., Inc. 14 p.
40756500 Anon (1988) Submission of Toxicological Evaluation study. Transmittal of 1 study.
40756501 Shpirt, M. (1975) Toxicological Evaluation of DDT, Hexachlorocyclohexane,
Tetramethylthiuram, Sevin, Cineb when acting on the Human Cell Cultures. A Translation of
Gigiena Truda i Professional'nye Zabolevaniia 17:32-34.
40768100 Gustafson, Inc. (1988) Submission of Environmental Fate Data in Support of Thiram
Reregistration. Transmittal of 4 studies.
40768101 Selman, F.; Moezpoor, E. (1987) Terresterial Soil Dissipation of Thiram on Turf in Georgia: Final
Report #34569. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 1082
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185
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40768102 Carpenter, M.; Fennessey, M. (1987) "Determination of the Photodegradation Rate of Carbon 14-
Thiram on the Surface of Soil": ABC Final Report #33572. Unpublished study prepared by
Analytical Bio-Chemistry Laboratories, Inc. 600 p.
40768103 Daly, D.; Cranor, W. (1988) Anaerobic Aquatic Metabolism of Carbon 14-Thiram: ABC Final
Report #33570. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 875 p.
40768104 Daly, D.; Cranor, W. (1988) "Aerobic Soil Metabolism of Carbon 14-Thiram": ABC Final Report
#33569. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 1475 p.
40773600 Gustafson, Inc. (1988) Submission of Toxicity Data to Support Registration Standard for Thiram
Technical. Transmittal of 1 study.
40773601 Kehoe, D. (1988) Thirteen-week Toxicity Study with Thiram in Rats: Proj. ID HLA 6111-110.
Unpublished study prepared by Hazleton Laboratories America, Inc.
223 p.
40779700 Gustafson, Inc. (1988) Submission of Data To Support Registration of Thiram Technical:
Toxicology Data. Transmittal of 1 study.
40779701 Kehoe, D. (1988) Four-week Range-finding Study with Thiram in Dogs: Project ID:
HLA 6111-109. Unpublished study prepared by Hazleton Laboratories America, Inc. 124 p.
40857600 US EPA (1984) Submission of Registration Standard in Support of Thiram. Transmittal of 1 study.
40857601 U.S. Environmental Protection Agency (1984) GS 122/Thiram: RS: Administrative Record.
Unpublished compilation with confidential attachment. 361 p.
40872700 Rhone-Poulenc Ag Co. (1988) Submission of Data To Support Registration of Rootone Brand F
Rooting Hormone: Product Chemistry Data. Transmittal of 1 study.
40872701 Scarborough, D. (1988) Rootone Brand F Rooting Hormone: Product Chemistry.
Unpublished study prepared by Rhone-Poulenc Ag Co. 8 p.
40878000 U.S. EPA (19??) Submission of Data for Registration Standard Requirement for Thiram:
Qualitative Use and Economic Benefit Data. Transmittal of 3 studies.
40878001 Pelletier, E. (1983) Qualitative Use Assessment for Thiram. Unpublished study prepared by U.S.
EPA. 11 p.
40878002 Vlier, L. (1982) Preliminary Quantitative Usage Analysis of Thiram. Unpublished study prepared
by U.S. EPA. 7 p.
40878003 Weiler, E. (1984) Analysis of the Economic Incentives to Maintain the Registration of Pesticide
Product Containing Thiram. Unpublished study prepared by U.S. EPA. 8 p.
186
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40953300 Gustafson, Inc. (1988) Submission of Soil Dissipation Data in Respect to Requirements for
Thiram Registration Standard. Transmittal of 1 study.
40953301 Selman, F. (1988) Terrestraial Soil Dissipation of Thiram on Turf in Missouri: Final Rept. #34570.
Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 178 p.
40974200 The Chas. H. Lilly Co. (1989) Submission of Toxicity Data to Support the Revised Labeling
for Lilly/Miller Bulb Dust. Transmittal of 4 studies.
40974201 Rutkowski, J. (1987) Acute Oral Toxicity (Limit) Test: Lilly-Miller Bulb Dust: Lot 6331: Project
No. 87G-0097. Unpublished study prepared by Toxikon Corp. lip.
40974202 Rutkowski, J. (1987) Single Dose Dermal Toxicity: Lilly-Miller Bulb Dust Lot 6331: Project No.
87G-0098. Unpublished study prepared by Toxikon Corp. 12 p.
40974203 Rutkowski, J. (1987) Primary Ocular Irritation Study: Lilly-Miller Bulb Dust: Lot 6331: Project
No. 87G-0100. Unpublished study prepared by Toxikon Corp. 22 p.
40974204 Rutkowski, J. (1987) Primary Dermal Irritation Study: Lilly-Miller Bulb Dust: Lot 6331: Project
No. 87G-0099. Unpublished study prepared by Toxikon Corp. 13 p.
40997300 Uniroyal Chemical Co., Inc. (1989) Submission of Chemistry and Toxicity Data in Support of Pro-
Gro. Transmittal of 7 studies.
40997301 Uniroyal Chemical Co., Inc. (1988) Pro-Gro Product Chemistry Data-A Compilation of Physical
and Chemical Characteristics. Unpublished study. 5 p.
40997302 Reagan, E. (1986) Acute Oral LD50 Study of Pro-Gro Sprague-Dawley Rats: FDRL #9257A.
Unpublished study prepared by Food & Drug Research Laboratories, Inc. 99 p.
40997303 Busch, B. (1986) Acute Dermal Toxicity Study of Pro-Gro in New Zealand White Rabbits:
FDRL# 9275A. Unpublished study prepared by Food & Drug Research Laboratories, Inc. 33 p.
40997304 Busch, B. (1986) Acute Inhalation Toxicity Study of Pro-Gro in Sprague-Dawley Rats: FDRL#
9276. Unpublished study prepared by Food & Drug Research Laboratories, Inc.59 p.
40997305 Busch, B. (1986) Primary Eye Irritation Study of Pro-Gro in New Zealand White Rabbits: FDRL#
9275A. Unpublished study prepared by Food & Drug Research Laboratories, Inc. 30 p.
40997306 Busch, B. (1986) Primary Dermal Irritation Study of Pro-Gro in New Zealand White Rabbits:
FDRL# 9275A. Unpublished study prepared by Food & Drug Research Laboratories, Inc. 25 p.
40997307 Kreuzmann, J. (1986) Delayed Contact Hypersensitivity Study in Guinea Pigs-Pro Gro:
Laboratory Project ID: 86-1356-21. Unpublished study prepared by Hill Top Research, Inc. 23 p.
187
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40998100 Chipman (1989) Submission of Chemistry Data in Support of Agrosol T. Transmittal of 1 study.
40998101 Barrientos, C. (1988) Agrosol T Systemic Soybean Seed Treatment Fungicide Product Chemistry
Statement. Unpublished study prepared by Chipman-Business Unit of C-I-L Inc. 46 p.
41006200 Gustafson, Inc. (1989) Submission of Residue Data to Support the Continued Registration of
Thiram. Transmittal of 3 studies.
41006201 Norris, K. (1989) Determination of the Metabolic Fate of CarbonThiram Orally Administered to
Lactating Goats: ADC Project No. 1057. Unpublished study prepared by Analytical Development
Corporation in cooperation with Colorado State Univ., Metabolic Laboratory. 56 p.
41006202 Norris, K. (1989) Determination of the Metabolic Fate of (Carbon)Thiram Orally
Administered to Laying Hens: ADC Project No. 1058. Unpublished study prepared by Analytical
Development Corp. in cooperation with Colorado State Univ., Metabolic Laboratory. 42 p.
41006300 Gustafson, Inc. (1989) Submission of Product Chemistry Data to Support the Thiram
Reregistration Standard of July, 1984. Transmittal of 4 studies.
41006301 Batorewicz, W. (1988) Determination of N-nitrosodimethylamine in Technical Thiram:
Laboratory Project ID 8846. Unpublished study prepared by Gustafson, Inc. 24 p.
41006302 Batorewicz, W.; Gaydosh, K. (1988) Recovery Determination of the Impurities Present in
Technical Thiram: Laboratory Project ID 88102. Unpublished study prepared by Uniroyal
Chemical Co., Inc. 20 p.
41006303 Batorewicz, W.; Gaydosh, K. (1988) Stability of Technical Thiram in Methanol: Laboratory
Project ID 8822. Unpublished study prepared by Uniroyal Chemical Co., Inc. 17 p.
41006304 Batorewicz, W.; Gaydosh, K. (1988) Storage Stability Test for Thiram: Laboratory Project ID
87123. Unpublished study prepared by Uniroyal Chemical Co., Inc. 13 p.
41037100 Uniroyal Chemical Co., Inc. (1989) Submission of Product Chemistry Data to Support Pro-Gro
Registration and Carboxin Onion Tolerance. Transmittal of 1 study.
41037101 Uniroyal Chemical Co., Inc. (1988) Pro-Gro Product Chemistry: I. Product Identity and
Composition n. Analysis and Certification of Product Ingredients. Unpublished study. 34 p.
41065000 Gustafson, Inc. (1989) Submission of Data To Support Reregistration of Thiram: Residue
Chemistry Data. Transmittal of 8 studies.
41065001 Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in Cotton:
Project ID: 01483; 6111-126J. Unpublished study prepared by Gustafson International Laboratory
in cooperation with Hazelton Laboratories. 262 p.
41065002 Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in Field Corn:
188
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41112401
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Project ID: 01486; 6111-126B. Unpublished study prepared by Gustafson International Research
Laboratory in cooperation with Hazelton Laboratories. 374 p.
Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in Sweet Corn:
Project ID: 01487; 6111-126A. Unpublished study prepared by Gustafson International Research
Laboratories. 282 p.
Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in
Succulent Beans: Project ID: 01484; 6111-126E. Unpublished study prepared by Gustafson
International Research Laboratory in cooperation with Hazelton Laboratories. 249 p.
Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in Dry Beans:
Project ID: 01493; 6111-126F. Unpublished study prepared by Gustafson International Research
Laboratory in cooperation with Hazelton Laboratories. 244 p.
Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in
Soybeans: Project ID: 01494; 6111-126C. Unpublished study prepared by Gustafson International
Research Laboratory in cooperation with Hazleton Laboratories. 384 p.
Ball, J. (1988) Residue of Thiram and its Monothioglucoside and Dithioglucoside in Wheat:
Project ID: 01492; 6111-126D. Unpublished study prepared by Gustafson International Research
Laboratory in cooperation with Hazleton Laboratories.
608 p.
Gustafson, Inc. (1989) Submission of Product Chemistry Data in Support of Thiram
Registration Standard. Transmittal of 1 study.
Rockwell, J. (1989) Product Chemistry Data: Gustafson Thiram Technical. Unpublished study
prepared by Gustafson, Inc. 21 p.
Hoechst Celanese (1989) Submission of Supplementary Toxicity Data in Support of
Reregi station of Endosulfan. Transmittal of 2 studies.
Berndt, G.; Dorn, E.; Leist, K.; et al. (1989) Endosulfan-Substance Technical: Combined Chronic
Toxicity/Carcinogenecity Study: 104-week Feeding in Rats...: Supplement: Project ID A 41265.
Unpublished study prepared by Hoechst Aktiengesellschaft. 83 p.
Dorn, E.; Leist, K.; Wagner, U.; et al. (1989) Endosulfan-Substance Technical:
Carcinogenicity Study in Mice: 24-Month Feeding Study...: Project ID A 41264. Unpublished
study prepared by Hoechst Aktiengesellschaft. 20 p.
Thiram Task Force (1989) Submission of Toxicity Study in Support of Thiram Registration
Standard. Transmittal of 2 studies.
Kehoe, D. (1989) 4-Week Dietary Range-Finding Study with Thiram in Mice: Lab Project
189
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Number: HLA/6111/127. Unpublished study prepared by Hazleton Laboratories America, Inc. 224
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41427901
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41427903
41427904
41427905
41427906
41498300
41498301
Nonis, K. (1989) Determination of Volatile Carbon 14-Residues from Rats Orally
Administered Carbon 14Thiram: Lab Project Number: 1113 A. Unpublished study prepared by
Analytical Development Corp. 16 p.
Akzo Chemie America (1987) Submission of Data To Support Registration of Thiram: Product
Chemistry Studies. Transmittal of 3 studies.
Obuch, D. (1986) Thiram Technical Cologne: Product Identity and Composition.
Unpublished study prepared by Akzo Chemie Nederland bv. 33 p.
Obuch, D. (1986) Thiram Technical Cologne: Analysis and Certification of Product
Ingredients. Unpublished study prepared by Akzo Chemie Nederland bv. lip.
Obuch, D. (1986) Thiram Technical Cologne: Physical and Characteristics. Unpublished study
prepared by Akzo Chemie Nederland bv. 6 p.
Gustafson, Inc. (1990) Submission of Product Chemistry and Toxicity Data in Support of
Registration of Gustafson Vitavax-Thiram-Lindane Flowable. Transmittal of 6 studies.
Mote, J.; Rosa, F.; Dempsay, A. (1990) Product Chemistry Data: Gustafson Vitavax-Thiram-
Lindane Flowable Fungicide-Insecticide: Lab Project Number: R208:99-1:IVQD. Unpublished
study prepared by Gustafson, Inc. 55 p.
Kuhn, J. (1989) Acute Oral Toxicity Study in Rats: Lab Project Number: 6497-89.
Unpublished study prepared by Stillmeadow, Inc. 24 p.
Kuhn, J. (1989) Vitavax-Thiram-Lindane Flowable: Acute Dermal Toxicity Study in Rabbits: Lab
Project Number: 6498-89. Unpublished study prepared by Stillmeadow, Inc. 13 p.
Kuhn, J. (1989) Vitavax-Thiram-Lindane Flowable: Primary Dermal Irritation Study in Rabbits:
Lab Project Number: 6500-89. Unpublished study prepared by Stillmeadow, Inc.
13 p.
Kuhn, J. (1989) Vitavax-Thiram-Lindane Flowable: Primary Eye Irritation Study in Rabbits: Lab
Project Number: 6499-89. Unpublished study prepared by Stillmeadow, Inc. 21 p.
Kuhn, J. (1989) Vitavax-Thiram-Lindane Flowable: Dermal Sensitization Study in Guinea Pigs:
Lab Project Number: 6501-89. Unpublished study prepared by Stillmeadow, Inc. 17 p.
Thiram Task Force (1990) Submission of Toxicity Data in Support of the Registration Standard
for Thiram. Transmittal of 3 studies.
Tesh, J.; McAnulty, P.; Willoughby, C.; et al. (1987) Thiram: Teratology Study in the Rat:
190
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41503608
Supplementary Report: Lab Project Number: 88/0672. Unpublished study prepared by Life
Science Research. 42 p.
Tesh, J.; Ross, F.; Crisp, V. (1987) Thiram: Teratology Study in the Rabbit: Supplementary
Report: Lab Project Number: 88/0621. Unpublished study prepared by Life Science Research. 23
P-
Tesh, J.; Ross, F.; King, V. (1987) Thiram: Teratology Study in the Rabbit: Second
Supplementary Report: Lab Project Number: 90/0048 : 90/TRK004/0048. Unpublished study
prepared by Life Science Research. 27 p.
Thiram Task Force II (1990) Submission of Residue Data in Support of the Registration Standard
for Thiram. Transmittal of 8 studies.
Rockwell, J. (1990) Residues of Thiram and its Metabolites in Lettuce: Lab Project
Number: HLA 6111-126K: 01488: 90-007. Unpublished study prepared by Gustafson
International Research Laboratory in association with Hazleton Laboratories America, Inc. 141 p.
Rockwell, J. (1989) Residues of Thiram and its Metabolites in Peas: Lab Project Number: 90-008:
HLA 6111-126G: 01489. Unpublished study prepared by Gustafson International Laboratories in
association with Hazleton Laboratories, Inc. 213 p.
Rockwell, J. (1989) Residues of Thiram and its Metabolites in Safflower: Lab Project Number: 90-
009: HLA 6111-126L: 01490. Unpublished study prepared by Gustafson International Laboratory
in association with Hazleton Laboratories America, Inc. 137 p.
Rockwell, J. (1990) Residues of Thiram and its Metabolites in Sugar Beets: Lab Project Number:
90-010: HLA 6111-126H: 01491. Unpublished study prepared by Gustafson International
Research Laboratory in association with Hazleton Laboratories, America, Inc. 181 p.
Rockwell, J. (1989) Residues of Thiram and its Metabolites in Table Beets: Lab Project Number:
90-011: HLA 6111-1261: 01485. Unpublished study prepared by Gustafson International Research
Laboratory in association with Hazleton Laboratories America, Inc. 184 p.
Kehoe, D. (1990) Kinetic Study with Thiram in Rats: Lab Project Number: HLA 6111-120.
Unpublished study prepared by Hazleton Laboratories America, Inc. 71 p.
Nonis, K. (1989) Quantitation of Carbon 14-Thiram in Samples of Tissues and Feces from Rat
Subchronic Dose Study: Lab Project Number: 1113B: 90-016. Unpublished study prepared by
Analytical Development Corp. 33 p.
Kehoe, D. (1990) 13-Week Toxicity Study with Thiram in Dogs: Lab Project Number: HLA 6111-
121: 90-017. Unpublished study prepared Hazleton Laboratories America, Inc. 237 p.
191
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41552100 Gustafson, Inc. (1990) Submission of Toxicological Data to Support the Registration of Vitavax-
Thiram Lindane Flowable. Transmittal of 1 study.
41552101 Holbert, M. (1990) Acute Inhalation Toxicity Study in Rats: Vitavax -thiram Lindane Flowable:
Lab Study No.: 7024-90. Unpublished study prepared by Stillmeadow, Inc. 25 p.
41625000 Wilbur-Ellis Co. (1990) Submission of Toxicity Data in Support of Thiram/Thiabendazole for
Agrosol T Flowable Systemic Soybean Seed Treatment Fungicide. Transmittal of 2 studies.
41625001 Lewis, R. (1990) Thiram/Thiabendazole: 4-Hour Acute Inhalation Toxicity Study in the Rat of a
125.5/3,48g/l SL Formulation: Lab Project Number: HR1983: CTL/P/3000. Unpublished study
prepared by ICI Central Toxicology Laboratory. 74 p.
41625002 Guest, R. (1990) Thiram/Thiabendazole 125.5/3.48 g/1 SC Formulation: Buehler Delayed Contact
Hypersensitivity Study in the Guinea Pig: Lab Project Number: 6/321: GG4911. Unpublished
study prepared by ICI Central Toxicology Laboratory. 26 p.
41726100 Wilbur-Ellis Co. (1990) Submission of Storage Stability Data To Support Conditional Registration
of Agrosol T Seed Treatment: Residue Chemistry Study. Transmittal of 1 study.
41726101 Price, G. (1990) 12 Month Storage Stability Study: Agrosol T: Lab Project Number: 171-4: SS-
028. Unpublished study prepared by ICI Chipman. 10 p.
41758300 Thiram Task Force (1991) Submission of Environmental Fate Data in support of Thiram
Registration Standard. Transmittal of 1 study.
41758301 Nonis, K. (1990) Determination of the Aqueous Photodegradation of Carbon 14-Thiram: Lab
Project Number: 1157. Unpublished study prepared by Analytical Development Corp. 58 p.
41840600 Thiram Task Force (1991) Submission of Environmental Fate Data to Support the
Registration Standard of Thiram. Transmittal of 1 Study.
41840601 Nonis, K. (1991) Determination of the Hydrolysis of carbon- 14Thiram: Lab Project Number:91-
007: 1156. Unpublished study prepared by Analytical Development Corp. 65 p.
41967900 Thiram Task Force II (1991) Submission of Data To Support Registration Standard for Thiram
Technical: Toxicology Study. Transmittal of 1 study.
41967901 Kehoe, D. (1991) 52-Week Dietary Chronic Toxicity Study with Thiram in Dogs: Final Report:
Lab Project Number: HLA 6111-112. Unpublished study prepared by Hazleton Laboratories
America, Inc. 545 p.
42002300 Trace Chemicals Inc. (1991) Submission of product chemistry data in support of an
application for amendment for an alternate formulation for Protector-L adding inert
ingredients. Transmittal of 1 study.
192
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42235701
42235702
42245600
42245601
Hartman, J. (1991) TCI Protector Seed Treatment: Product Chemistry: Unpublished
study prepared by Trace Chemicals Inc. 39 p.
Thiram Task Force c/o Gustafson, Inc. (1991) Submission of Data To Support Registration
Standard Requirements for Thiram Technical: Toxicology Studies. Transmittal of 1 study.
York, R. (1991) Two-Generation Reproduction Study in Rats Using Thiram: Lab Project Number:
399-104. Unpublished study prepared by International Research and Development Corp. 764 p.
Thiram Task Force II (1992) Submission of toxicity data to support the registration standard for
Thiram. Transmittal of 1 study.
Kehoe, D. (1991) 104-Week Combined Chronic Toxicity and Carcinogenicity Study with Thiram
in Rats: Lab Project Number: HLA 6111 113. Unpublished study prepared by Hazleton Labs
America, Inc. 2513 p.
The Scotts Co. (1992) Submission of product chemistry data in support of registration of Fluid
Fungicide m. Transmittal of 1 study.
Snyder, V. (1991) Fluid Fungicide HI: Product Chemistry Storage Stability. Unpublished study
prepared by The O. M. Scott & Sons Co. 4 p.
Thiram Task Force (1992) Submission of Data To Support Registration Standard for Thiram:
Toxicology Study. Transmittal of 1 study.
York, R. (1992) Developmental Toxicity Study in New Zealand White Rabbits: Thiram Technical:
Lab Project Number: 399-121. Unpublished study prepared by International Research and
Development Corp. 164 p.
Thiram Task Force II (1992) Submission of toxicity (metabolism and excretion) data to support the
registration standard for Thiram. Transmittal of 2 studies.
Gay, M.; Norris, K.; Nomeir, A.; et al. (1991) Metabolism of Orally Administered carbon
14Thiram in Rats: Lab Project Number: 8767: 8833: 8839. Unpublished study prepared by Biotek,
Inc., Arthur D. Little, Inc.; Analytical Dev. Corp.; and Uniroyal Chem., Inc. 229 p.
Banijamali, A.; Gay, M.; Kehoe, D. et al. (1990) Elimination and Distribution of Thiram
Following Nine Week Sub-Chronic Administration in Rats (Multiple Dose Treatment): Lab
Project Number: 87114: 8850: 8850-1. Unpublished study prepared by Hazleton Labs, Inc.;
Uniroyal Chem., Inc. and Analytical Dev. Corp. 151 p.
Thiram Task Force (1992) Submission of Data To Support Registration Standard for Thiram
Technical: Environmental Fate Studies. Transmittal of 2 studies.
Norris, K. (1991) Determination of the Aqueous Photodegradation of carbon 14-Thiram:
193
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Addendum No. 1: Lab Project Number: 1157. Unpublished study prepared by Analytical
Development Corp., (ADC). 6 p.
42245602 Norris, K. (1991) Determination of Hydrolysis of carbon 14-Thiram: Addendum No. 1: Lab
Project Number: 1156. Unpublished study prepared by Analytical Development Corp., (ADC). 7
P-
42313400 Thiram Task Force II (1992) Submission of toxicity data to support the Thiram registration
standard (via Gustafson, Inc.). Transmittal of 1 study.
42313401 Trutter, J. (1992) Oncogenicity Study in Mice with Thiram: Lab Project Number: 798-223.
Unpublished study prepared by Hazleton Washington, Inc. 2965 p.
42319200 Daniel R. Freeman (1992) Submission of product chemistry in support of the registration of Good-
Bye Deer. Transmittal of 1 study.
42319201 Freeman, D.; Furdyna, P.; Poche, R. (1992) Physical and Chemical Properties of
Good-Bye Deer: Product Chemistry: Lab Project Number: 4-10-92: 92-001. Unpublished study
prepared by Alcor Products and Genesis Laboratories. 27 p.
42323600 Gustafson, Inc. (1992) Submission of product chemistry and toxicity data to support the
registration of Raxil Thiram Flowable Fungicide. Transmittal of 7 studies.
42323601 Mote, J.; Dempsey, A. (1991) Product Chemistry Data: Raxil Thiram Flowable Fungicide: Lab
Project Number: M104: 76-1. Unpublished study prepared by Gustafson, Inc. 35 p.
42323602 Kuhn, J. (1991) Acute Oral Toxicity Study in Rats: Thiram Raxil FL: Lab Project Number: 8218-
91. Unpublished study prepared by Stillmeadow, Inc. 21 p.
42323603 Kuhn, J. (1991) Acute Dermal Toxicity Study in Rabbits: Thiram Raxil FL: Lab Project Number:
8219-91. Unpublished study prepared by Stillmeadow, Inc. 14 p.
42323604 Holbert, M. (1992) Acute Inhalation Toxicity Study in Rats: Thiram Raxil FL: Lab Project
Number: 8220-91. Unpublished study prepared by Stillmeadow, Inc. 43 p.
42323605 Kuhn, J. (1991) Primary Eye Irritation Study in Rabbits: Thiram Raxil FL: Lab Project Number:
8221-91. Unpublished study prepared by Stillmeadow, Inc. 21 p.
42323606 Kuhn, J. (1991) Primary Dermal Irritation Study in Rabbits: Thiram Raxil FL: Lab Project
Number: 8222-91. Unpublished study prepared by Stillmeadow, Inc. 15 p.
42323607 Kuhn, J. (1991) Dermal Sensitization Study in Guinea Pigs: Thiram Raxil FL: Lab Project
Number: 8223-91. Unpublished study prepared by Stillmeadow, Inc. 19 p.
42399600 Thiram Task Force II (1992) Submission of residue data to support the registration
standard for Thiram. Transmittal of 5 studies.
194
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42399601 Christman, P. (1992) Determination of Thiram and Its Metabolites in Crops Addendum to Final
Report: Lab Project Number: HLA 6111-126 A-L; 92-011. Unpublished study prepared
by Hazleton Labs America, Inc.; Gustafson, Inc. and Uniroyal Chem. Co. 76 p.
42399602 Rockwell, J. (1992) Residues of Thiram and Its Metabolite in Alfalfa: Lab Project Number: HLA
6111-134A; 01777; 92-012. Unpublished study prepared by Hazleton Labs America, Inc.;
Gustafson Intl. Res. Lab ; Uniroyal Chem. Co. and others. 97 p.
42399603 Rockwell, J. (1992) Residues of Thiram and Its Metabolite in Cabbage: Lab Project
Number: HLA 6111-134C; 017773; 92-013. Unpublished study prepared by Hazleton Labs
America, Inc.; Gustafson, Inc.; Uniroyal Chem. Co. and others.
127 p.
42399604 Rockwell, J. (1992) Residues of Thiram and Its Metabolite in Cucumbers: Lab Project Number:
HLA 6111-134D; 01774; 92-014. Unpublished study prepared by Hazleton Labs America, Inc.;
Gustafson Intl. Res. Lab; Uniroyal Chemical Co. and others. 141 p.
42399605 Rockwell, J. (1992) Residues of Thiram and Its Metabolite in Fresh and Processing
Tomatoes: Lab Project Number: HLA 6111-134F; 01775; 92-015. Unpublished study prepared by
Hazleton Labs America, Inc.; Gustafson Intl. Res. Lab; Uniroyal Chemical Co. and others. 145 p.
42411500 Rockland Corp. (1992) Submission of product chemistry data in support of the registrations of
Hormo Root A, B, and C. Transmittal of 3 studies.
42411501 Lemm, J. (1992) Rockland Hormo Root A: Product Chemistry: Lab Project Number: 010642.
Unpublished study prepared by Chemtest Laboratories, Inc. 7 p.
42411502 Lemm, J. (1992) Rockland Hormo Root B: Product Chemistry: Lab Project Number: 011362.
Unpublished study prepared by Chemtest Laboratories, Inc. 7 p.
42411503 Lemm, J. (1992) Rockland Hormo Root C: Product Chemistry: Lab Project Number: 011362.
Unpublished study prepared by Chemtest Laboratories, Inc. 7 p.
42427100 UCB Chemicals (1992) Submission of toxicity data in support of the registration standard for
Thiram. Transmittal of 5 studies.
42427101 Baldrick, P. (1992) Acute Oral Toxicity to the Rat of Thiram 75 WG: Lab Project Number:
91862D/UCB 399/AC. Unpublished study prepared by Huntingdon Research Center, Ltd. 27 p.
42427102 Baldrick, P. (1992) Acute Dermal Toxicity to Rabbits of Thiram 75 WG: Lab Project Number:
91853D/UCB 400/AC. Unpublished study prepared by Huntingdon Research Center, Ltd. 21 p.
42427103 Liggett, M.; McRae, L. (1991) Eye Irritation to Rabbits with Thiram 75 WG: Lab Project Number:
91737D/UCB 402/SE. Unpublished study prepared by Huntingdon Research Center, Ltd. 16 p.
195
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42466400
42466401
42488300
42488301
42488302
42488303
42514400
42514401
42604000
42604001
42604002
42604003
Liggett, M.; McRae, L. (1991) Skin Irritation to Rabbits with Thiram 75 WG: Lab Project
Number: 91736D/UCB 401/SE. Unpublished study prepared by Huntingdon Research Center, Ltd.
16 p.
Daamen, P. (1991) Contact Hypersensitivity to Thiram 75 WG in the Albino Guinea Pig (Split
Adjuvant Test): Lab Project Number: RCC NOTOX 061526. Unpublished study prepared by RCC
Notox B.V. 30 p.
UCB Chemicals Corp. (1992) Submission of toxicity data under FIFRA 6(A)(2) status (adverse
effects) to support the registration standards for Thiram. Transmittal of 1 study.
Larson, P. (1992) Letter Sent to Carol Peterson, OPP dated August 31, 1992 from Paul Larson,
UCB Chemicals regarding a two-week preliminary inhalation study in rats with Thiram. Prepared
by UCB Chemicals. 16 p.
UCB Cheemicals Corp. (1992) Submission of aquatic toxicity data to to support Thiram
registration standard. Transmittal of 3 studies.
Thompson, R; Croudace, C.; Grinell, A. (1992) Thiram: Acute Toxicity to Larvae of the Pacific
Oyster (Crassostrea gigas): Lab Project Number: W199/C: BL4547/B. Unpublished study
prepared by Imperial Chemical Industries PLC. 20 p.
Thompson, R; Croudace, C.; Grinell, A. (1992) Thiram: Acute Toxicity to Mysid Shrimp
(Mysidopsis bahia): Lab Project Number: W199/D: BL4562/B. Unpublished study prepared by
Imperial Chemical Industries PLC. 19 p.
Larson, P. (1992) Addendum No. 1 to UCB 72-3 Study Reports Supporting Documentation of
Test Material. Unpublished study prepared by UCB. 6 p.
UCB Chemicals Corp. (1992) Submission of toxicity data to support Thiram registration standard.
Transmittal of 1 study.
Croudace, C.; Caunter, J.; Johnson, P. (1992) Thiram: Acute Toxicity to Sheepshead Minnow
(Cyprinodon variegatus): Lab Project Number: W199/B. Unpublished study prepared by Imperial
Chemical Industries PLC. 22 p.
Gustafson (1992) Submission of product chemistry and toxicity data in support of the registration
of Gustafson 42-S Thiram Fungicide. Transmittal of 6 studies.
Rosa, F.; Dempsay, A. (1992) Product Chemistry Data: Gustafson 42S Thiram Fungicide:
Lab Project Number: M12190616: 92-030. Unpublished study prepared by Gustafson, Inc. 64 p.
Reagan, E. (1986) Acute Oral LD50 Study of Gustafson 42-S Thiram Fungicide in
Sprague-Dawley Rats: Lab Project Number: 9184A: 86-005. Unpublished study prepared by Food
& Drug Research Labs, Inc. 134 p.
Busch, B. (1986) Acute Dermal Toxicity Study of Gustafson 42-S Thiram Fungicide in New
196
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Zealand White Rabbits: Lab Project Number: 9184A: 86-006. Unpublished study prepared by
Food & Drug Research Labs, Inc. 32 p.
42604004 Allan, S. (1991) Acute Dermal Toxicity to the Rat: Gustafson 42-S Thiram Fungicide: Lab Project
Number: 91877D/URL 79/AC: 92-029. Unpublished study prepared by Huntingdon Research
Centre Ltd. 20 p.
42604005 Busch, B. (1986) Primary Eye Irritation Study of Gustafson 42-S Thiram Fungicide in New
Zealand White Rabbits: Lab Project Number: 9184A: 86-008. Unpublished study prepared by
Food & Drug Research Labs, Inc. 33 p.
42604006 Busch, B. (1986) Primary Dermal Irritation Study of Gustafson 42-S Thiram Fungicide in New
Zealand White Rabbits: Lab Project Number: 9184A: 86-007. Unpublished study prepared by
Food & Drug Research Labs, Inc. 27 p.
42624200 Gustafson, Inc. (1991) Submission of product chemistry data in support of the registration of
Terraclor 80% Dust Concentrate. Transmittal of 1 study.
42624201 Rockwell, J. (1991) Product Chemistry Information: Terraclor 80% Dust Concentrate: Lab Project
Number: 91-045. Unpublished study prepared by Gustafson, Inc. and Uniroyal Chemical Co., Inc.
25 p.
42624300 AKZO (1993) Supplemental submission of product chemistry data in support of the phase 3
response for Methyl Nonyl Ketone. Transmittal of 1 study.
42624301 Lawson, P. (1993) Methyl Nonyl Ketone (MNK): Description of Each Beginning Material in
Manufacturing Process: Supplemental Information. Unpublished study prepared by AKZO
Chemicals, Inc. 17 p.
42642500 UCB Chemicals Corp. (1993) Submission of toxicity data in support of the data call-in for thiram.
Transmittal of 1 study.
42642501 Edwards, J.; McRae, L.; Gibson, W.; et al. (1992) Thiram Technical Twenty-one Day Dermal
Toxicity Study in Rabbits: Lab Project Number: UCB 421/920767. Unpublished study prepared by
Huntingdon Research Centre Ltd. 118 p.
42646000 UCB Chemicals (1993) Submission of toxicity data in support of FIFRA 6(a)(2)
requirements/data call-in for Thiram. Transmittal of 1 study.
42646001 Douglas, M. (1993) Thiram: Algal Growth Inhibition (Selenastrum capricornutum): Lab Project
Number: UCB 442/921255. Unpublished study prepared by Huntingdon Research Centre Ltd. 30
P-
42677500 Thiram Task Force II (1993) Submission of residue data in support of the thiram registration
standard. Transmittal of 1 study.
197
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42907701
42907702
42907703
42907704
42907705
42907706
42907707
42907708
42910200
42910201
42910400
Nonis, K. (1993) Determination of the Metabolic Fate of (carbon 14)-Thiram Orally
Administered to Lactating Goats: Revised Final Report: Lab Project Number: 1057: 1057-1.
Unpublished study prepared by Analytical Development Corp. and Colorado State Univ. 94 p.
Daniel R. Freeman (1993) Submission of Product Chemistry, Toxicology and Efficacy Data in
Support of Registration of Repel Plus Dog and Cat Repellent. Transmittal of 8 Studies.
Shapiro, R. (1993) EPA Acute Oral Toxicity Limit Test (with Rats): Lot #43 (Repel Plus Dog and
Cat Repellent): Lab Project Number: T-2435. Unpublished study prepared by Product Safety Labs.
16 p.
Shapiro, R. (1993) EPA Acute Dermal Toxicity Limit Test (with Rabbits): Lot #43 (Repel Plus
Dog and Cat Repellent): Lab Project Number: T-2438. Unpublished study prepared by Product
Safety Labs. 15 p.
Shapiro, R. (1993) EPA Primary Dermal Irritation Test (with Rabbits): Lot #43 (Repel Plus Dog
and Cat Repellent): Lab Project Number: T-2437. Unpublished study prepared by Product Safety
Labs. 15 p.
Shapiro, R. (1993) EPA Primary Eye Irritation: Animal Repellent Lot #43 (Repel Plus Dog and
Cat Repellent): (with Rabbits): Lab Project Number: T-2196. Unpublished study prepared by
Product Safety Labs. 21 p.
Shapiro, R. (1993) EPA Guinea Pig Sensitization (Buehler): Lot #43 (Repel Plus Dog and Cat
Repellent): Lab Project Number: T-2439. Unpublished study prepared by Product Safety Labs. 22
P-
Savage, J. (1993) REPEL Animal Repellent Chemical and Physical Properties: Lab Project
Number: 93009. Unpublished study prepared by Genesis Labs. 24 p.
Savage, J. (1993) REPEL Animal Repellent: Purity Analysis: Lab Project Number: 93001.
Unpublished study prepared by Genesis Labs. 30 p.
Freeman, D. (1993) Repel Plus Dog and Cat Repellent: Efficacy. Unpublished study
prepared by Rancho Mirage in cooperation with the University of Southern California. 10 p.
UCB Chemicals Corp. (1993) Submission of Product Chemistry Data in Support of UCB's Thiram
Technical Registration. Transmittal of 1 study.
Mullee, D. (1993) Thiram 98.5% Technical Product Determination of Corrosion
Characteristics: Lab Project Number: 457/22. Unpublished study prepared by Safepharm
Laboratories Limited. 10 p.
UCB Chemicals Corp. (1993) Submission of Storage Stability Data in Response to EPA Letter
Dated Sep. 2, 1992 in Support of Thiram Technical Registration. Transmittal of 1 Study.
198
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42943701
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43012701
43014400
43014401
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43028701
Van Bever, A.; Verberckt, J. (1988) TMTD Technical (Phyto) Grade: Storage Stability: Lab
Report: WL No. 07/88. Unpublished study prepared by UCB Chemical Sector. 14 p.
Thiram Task Force II (1993) Submission of Acute Toxicology Data in Support of Thiram
Registration Standard. Transmittal of 1 Study.
Driscoll, C.; Hurley, J. (1993) Thiram: Single Exposure Peroral (Gavage) Neurotoxicity Study in
Rats: Lab Project Number: 91N0126. Unpublished study prepared by Union Carbide Chemicals
and Plastics Co., Inc. 467 p.
Gustafson, Inc. (1993) Submission of Environmental Fate Data for Thiram Technical in Support of
Registration Standard. Transmittal of 1 Study.
Nonis, K. (1993) Determination of the Metabolic Fate of (Carbon-14) Thiram Orally
Administered to Laying Hens: Final Report: Lab Project Number: 1058: 1058-1. Unpublished
study prepared by Analytical Development Corporation (ADC); Colorado State University (CSU)
Metabolic Lab. 80 p.
Thiram Task Force II (1993) Submission of Metabolism Data in Support of Thiram
Registration Standard. Transmittal of 1 Study.
Nonis, K. (1993) Determination of the Metabolic Fate of (Carbon 14)-Thiram Orally
Administered to Laying Hens: Addendum No. 1 to Final Report: Lab Project Number: 1058:
1058-1. Unpublished study prepared by Analytical Development Corp. and Colorado State
University Metabolic Lab. 8 p.
Thiram Task Force II (1993) Submission of Toxicology Data in Support of Registration Standard
for Thiram. Transmittal of 1 Study.
Driscoll, C.; Hurley, J. (1993) Thiram: Ninety-day Dietary Neurotoxicity Study in Sprague Dawley
Rats: Lab Project Number: 91N0127. Unpublished study prepared by Bushy Run Research
Center, Union Carbide Chemicals and Plastics Co. Inc. 413 p.
Daniel R. Freeman Co. (1993) Submission of Product Chemistry Data for Repel Plus Dog and Cat
Repellent in Support of Registration. Transmittal of 1 Study.
Freeman, D. (1993) Procedure for Achieving Homogenized Mixture: Thiram and
Orthophenylphenol. Unpublished study prepared by Daniel R. Freeman Co. 4 p.
Gustafson Inc. (1993) Submission of product chemistry and toxicity data in support of registration
for Baytan-Anchor-Thiram Flowable Fungicide. Transmittal of 7 studies.
Rosa, F.; Finch, C. (1993) The Physical and Chemical Characteristics of Baytan-Anchor-Thiram
FS end-use Product: Amended Report: Lab Project Number: F101/52/1: PC93002. Unpublished
199
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study prepared by Gustafson, Inc. 60 p.
43028702 Kuhn, J. (1993) Baytan Anchor Thiram Flowable: Acute Oral Toxicity Study in Rats: Lab Project
Number: 0010/93. Unpublished study prepared by Stillmeadow, Inc. 25 p.
43028703 Kuhn, J. (1993) Baytan Anchor Thiram Flowable: Acute Dermal Toxicity in Rats: Lab Project
Number: 0011/93. Unpublished study prepared by Stillmeadow, Inc.
12 p.
43028704 Holbert, M. (1993) Baytan Anchor Thiram Flowable: Acute Inhalation Toxicity Study in Rats: Lab
Project Number: 0012/93. Unpublished study prepared by Stillmeadow, Inc. 38 p.
43028705 Kuhn, J. (1993) Baytan Anchor Thiram Flowable: Primary Eye Irritation Study in Rabbits: Lab
Project Number: 0013/93. Unpublished study prepared by Stillmeadow, Inc. 18 p.
43028706 Kuhn, J. (1993) Baytan Anchor Thiram Flowable: Primary Dermal Irritation Study in Rabbits: Lab
Project Number: 0014/93. Unpublished study prepared by Stillmeadow, Inc. 14 p.
43028707 Kuhn, J. (1993) Baytan Anchor Thiram Flowable: Dermal Sensitization Study in Guinea Pigs: Lab
Project Number: 0015/93. Unpublished study prepared by Stillmeadow, Inc. 18 p.
43054600 Gustafson, Inc. (1993) Submission of Toxicity Data for KODIAK T in Support of
Registration. Transmittal of 7 Studies.
43054601 Rosa, F. (1993) Product Chemistry Data: Kodiak T: Lab Project Number: T39130001X: 93-026.
Unpublished study prepared by Gustafson, Inc. and Trace Chemicals, Inc. 48 p.
43054602 Kuhn, J. (1993) Acute Oral Toxicity Study in Rats: Kodiak T: Lab Project Number: 0076-93:93-
027. Unpublished study prepared by STILLMEADOW, Inc. 13 p.
43054603 Kuhn, J. (1993) Acute Dermal Toxicity Study in Rabbits: Kodiak T: Lab Project Number:0077-93:
93-028. Unpublished study prepared by STILLMEADOW, Inc. 13 p.
43054604 Holbert, M. (1993) Acute Inhalation Toxicity Study in Rats: Kodiak T: Lab Project Number: 0078-
93: 93-029. Unpublished study prepared by STILLMEADOW, Inc. 21 p.
43054605 Kuhn, J. (1993) Primary Eye Irritation Study in Rabbits: Kodiak T: Lab Project Number: 0079-93:
93-030. Unpublished study prepared by STILLMEADOW, Inc. 19 p.
43054606 Kuhn, J. (1993) Primary Dermal Irritation Study in Rabbits: Kodiak T: Lab Project Number: 0080-
93: 93-031. Unpublished study prepared by STILLMEADOW, Inc. 15 p.
43054607 Kuhn, J. (1993) Dermal Sensitization Study in Guinea Pigs: Kodiak T: Lab Project Number: 0081-
93: 93-032. Unpublished study prepared by STILLMEADOW, Inc. 19 p.
43122900 UCB Chemical Corp. (1994) Submission of residue data in support of FIFRA 6(a)(2) requirements
200
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for thiram. Transmittal of 1 study.
43122901 Larson, P. (1994) Letter Sent to Office of Pesticide Program dated February 9, 1994: (Residues
Found Over Tolerance on Apples: Thiram). Prepared by UCB Chemical Corp. 6 p.
43287200 R & M Regulatory Services (1994) Submission of Product Chemistry Data in Support of
Application for Registration of R & M Rabbit and Deer Repellent. Transmittal of 1 Study.
43287201 Adams, R. (1994) Product Chemistry Series 61, 62, and 63 for: R & M Rabbit and Deer
Repellent. Unpublished study prepared by R & M Regulatory Services. 8 p.
43287300 R & M Regulatory Services (1994) Submission of Product Chemistry Data in Support of
Application for Registration of R & M Rabbit and Deer Repellent. Transmittal of 1 Study.
43287301 Adams, R. (1994) Product Chemistry Series 61, 62, and 63 for: R & M Rabbit and Deer
Repellent. Unpublished study prepared by R & M Regulatory Services. 8 p.
43287400 AmeriBrom, Inc. (1994) Submission of Efficacy Data for Repels Plus Dog and Cat Repellent in
Support of Registration. Transmittal of 1 study.
43287401 Fisher, C. (1994) Efficacy: Repels Plus Dog and Cat Repellent. Unpublished study prepared by
Univ. of Southern California. 14 p.
43299100 Daniel R. Freeman (1994) Submission of efficacy data in support of registration of Repels Plus
Dog and Cat Repellent. Transmittal of 1 study.
43299101 Fisher, C. (1994) Efficacy: Repels Plus Dog and Cat Repellent: Lab Project Number:
DOG/AND/CAT/REPELLENCY/TEST. Unpublished study. 27 p.
43315300 Akzo Chemicals Inc. (1994) Submission of Toxicity Data in Support of FIFRA 6(a)(2)
Requirements for Tetramethylthiuram Disulfide. Transmittal of 1 Study.
43315301 Henrich, R. (1994) Letter Sent to Office of Pesticide Programs dated July 18, 1994
concerning an acute aquatic toxicity study conducted in guppies with tetramethylthiuram isulfide.
Prepared by Akzo Chemicals Inc. 1 p.
43449000 Thiram Task Force II (1994) Submission of Environmental Fate Data in Support of Thiram
Registration Standard. Transmittal of 3 Studies.
43449001 Liu, D.; Robinson, R. (1994) Uptake and Translocation of (carbon 14) Thiram in Plants from
Treated Soybean Seed: Lab Project Number: XBL92040: RPT00158: 92161. Unpublished study
prepared by XenoBiotic Labs, Inc. 429 p.
43449002 Liu, D.; Robinson, R. (1994) Uptake and Translocation of (carbon 14) Thiram in Plants from
Treated Wheat Seed: Lab Project Number: XBL92031: RPT00203: 91181. Unpublished study
prepared by XenoBiotic Labs, Inc. 147 p.
201
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43449003 Liu, D.; Robinson, R. (1994) Distribution and Metabolism of (carbon 14) Thiram in Plants from
Treated Sugarbeet Seed: Lab Project Number: XBL93031: RPT00202: 92252. Unpublished study
prepared by XenoBiotic Labs, Inc. 185 p.
43562200 UCB Chemicals Corp. (1995) Submission of Metabolism Data in Support of Thiram
Reregistration. Transmittal of 1 Study.
43562201 Wyss-Benz, M. (1994) (Carbon 14)-Thiram: Plant Metabolism Study in Field Grown Apple: Lab
Project Number: 319588. Unpublished study prepared by RCC Umweltchemie AG. 139 p.
43612500 Thiram Task Force II (1995) Submission of toxicity data in support of the Thiram
registration standard. Transmittal of 6 studies.
43612501 Beavers, J.; Chafey, K.; Mitchell, L. et al. (1995) Thiram Technical: A Reproduction Study with
the Mallard: Lab Project Number: 357/104: CHR24. Unpublished study prepared by Wildlife
International Ltd. 278 p.
43612502 Beavers, J.; Chafey, K.; Mitchell, L. et al. (1995) Thiram Technical: A One Generation
Reproduction Study with the Northern Bobwhite (Colinus virginianus): Amended: Lab Project
Number: 357/103: CHR24. Unpublished study prepared by Wildlife International Ltd. 250 p.
43612503 Beavers, J.; Trumbull, S.; Grimes, J. et al. (1995) Thiram Technical: A Pilot Reproduction Study
with the Mallard (Anas platyrhynchos): Lab Project Number: 357/102: CHR17. Unpublished study
prepared by Wildlife International Ltd. 220 p.
43612504 Beavers, J.; Trumbull, S.; Grimes, J. et al. (1995) Thiram Technical: A Pilot Reproduction Study
with the Northern Bobwhite (Colinus virginianus): Lab Project Number: 357/101: CHR17.
Unpublished study prepared by Wildlife International Ltd. 217 p.
43612505 Beavers, J.; Haberlein, D.; Grimes, J. et al. (1995) Thiram Technical: A Palatability/
Repellancy Study with the Mallard (Anas platyrhynchos) Under Multiple Choice Conditions: Lab
Project Number: 357/106: CHR17. Unpublished study prepared by Wildlife International Ltd. 183
P-
43612506 Beavers, J.; Haberlein, D.; Grimes, J. et al. (1995) Thiram Technical: A Palatability/
Repellancy Study with the Northern Bobwhite (Colinus virginianus) Under Multiple Choice
Conditions: Lab Project Number: 357/105: CHR17. Unpublished study prepared by Wildlife
International Ltd. 184 p.
43628500 UCB Chemicals Corp. (1995) Submission of Environmental Fate Data in Support of the
Registration Standard of Thiram. Transmittal of 1 Study.
43628501 Wyss-Benz, M. (1995) (Carbon 14)-Thiram: Degradation and Metabolism in an Anaerobic
Aquatic System: Revised Report: Lab Project Number: 329635. Unpublished study prepared by
RCC Umweltchemie AG. 110 p.
202
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43631800
Gustafson, Inc. (1995) Submission of Toxicity Data in Support of the Registration of
FA-12 THIRAM. Transmittal of 6 Studies.
43631801
43631802
43631803
43631804
43631805
43631806
43661800
43661801
43666100
43666101
43694700
43694701
43702300
Kuhn, J. (1994) FA-12 Thiram: Acute Oral Toxicity Study in Rats: Lab Project
Numbers: 1077-94: S9-FF81-1. Unpublished study prepared by Stillmeadow, Inc.
21 p.
Kuhn, J. (1994) FA-12 Thiram: Acute Dermal Toxicity Study in Rabbits: Lab Project
Numbers: 1078-94: S9-FF81-2. Unpublished study prepared by Stillmeadow, Inc. 15 p.
Kuhn, J. (1994) FA-12 Thiram: Acute Inhalation Toxicity Study in Rats: Lab Project
Numbers: 1079-94: S9-FF81-3. Unpublished study prepared by Stillmeadow, Inc. 35 p.
Kuhn, J. (1994) FA-12 Thiram: Primary Eye Irritation Study in Rabbits: Lab Project
Numbers: 1080-94: S9-FF81-4. Unpublished study prepared by Stillmeadow, Inc. 22 p.
Kuhn, J. (1994) FA-12 Thiram: Primary Dermal Irritation Study in Rabbits: Lab Project
Numbers: 1081-94: S9-FF81-5. Unpublished study prepared by Stillmeadow, Inc. 14 p.
Kuhn, J. (1994) FA-12 Thiram: Dermal Sensitization Study in Guinea Pigs: Lab Project
Numbers: 1082-94: S9-FF81-6. Unpublished study prepared by Stillmeadow, Inc. 18 p.
UCB Chemicals Corp. (1995) Submission of Environmental Fate Data in Support of the
Registration Standard for Thiram. Transmittal of 1 Study.
Burri, R. (1995) Photodegradation Study of (Carbon 14)-Thiram on Soil: Lab Project
Number: 326171. Unpublished study prepared by RCC Umweltchemie AG. 113 p.
Gustafson, Inc. (1995) Submission of Product Chemistry Data in Support of
Application for Registration of FA-12 Thiram. Transmittal of 1 Study.
Mote, J.; Dempsay, A. (1994) Product Chemistry Data: Apron Thiram Flowable
Fungicide: Lab Project Number: PC/93-010. Unpublished study prepared by Gustafson,
Inc. 72 p.
UCB Chemicals Corp. (1995) Submission of Residue Chemistry Data in Support of
FIFRA 6(a)(2) for Thiram and Ziram. Transmittal of 1 Study.
Sielaty, R. (1995) Letter Sent to Office of Pesticide Programs dated June 22, 1995 Re:
UCB thiram and ziram field residue studies. Prepared by UCB Chemicals Corp. 2 p.
UCB Chemicals Corp. (1995) Submission of Residue Data in Support of FIFRA 6(a)(2)
for Thiram and Ziram. Transmittal of 1 Study.
203
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43702301
43727100
43727101
43727102
43727103
43727104
43727105
43727106
43734900
43734901
43735600
43735601
Sielaty, R. (1995) Letter sent to Office of Pesticide Programs dated June 30, 1995
concerning analyses of samples involved in earlier-reported instance of over-tolerance
residues of thiram and ziram in apples. Prepared by Compliance Services Int'l. 2 p.
Uniroyal Chemical Co., Inc. (1995) Submission of Toxicology Data in Support of the
Registration of Vitavax 200FF. Transmittal of 6 Studies.
Allan, S. (1992) Vitavax 200FF: Acute Oral Toxicity to the Rat: Lab Project Number:
VIT00118-05: 911001D/URL 81/AC. Unpublished study prepared by Uniroyal
Chemicals, Ltd. and Huntingdon Research Centre, Ltd. 52 p.
Allan, S. (1992) Vitavax 200FF: Acute Dermal Toxicity to the Rat: Lab Project
Number: VIT0018-02: 91937D/URL 82/AC. Unpublished study prepared by Uniroyal
Chemicals, Ltd. and Huntingdon Research Centre, Ltd. 19 p.
Hilaski, R. (1994) Acute Inhalation Toxicity Evaluation on Vitavax 200 Flowable
Fungicide (17%-17%) in Rats: Amended Final Report: Lab Project Number: 399-156:
VIT134. Unpublished study prepared by IRDC. 44 p.
Liggett, M. (1992) Vitavax 200 FF: Eye Irritation to the Rabbit: Lab Project Number:
VIT00118-03: 920023D/URL 84/SE. Unpublished study prepared by Uniroyal
Chemicals Ltd. and Huntingdon Research Centre, Ltd. 13 p.
Liggett, M. (1992) Vitavax 200 FF: Skin Irritation to the Rabbit: Lab Project Number:
VIT 00118-04: 920022D/URL 83/SE. Unpublished study prepared by Uniroyal
Chemicals Ltd. and Huntingdon Research Centre, Ltd. 13 p.
Parcell, B. (1992) Vitavax 200 FF: Skin Sensitisation in the Guinea Pig: Lab Project
Number: VIT 00118-01: 920038D/URL 85/SS. Unpublished study prepared by
Uniroyal Chemicals Ltd. and Huntingdon Research Centre, Ltd. 26 p.
UCB Chemicals Corp. (1995) Submission of Environmental Fate Data in Support of the
Registration Standard for Thiram. Transmittal of 1 Study.
Morgenroth, U.; Mueller-Kallert, H. (1995) (Carbon 14)-Thiram: Degradation and
Metabolism in One Soil Incubated Under Aerobic Conditions: Lab Project Number:
326182. Unpublished study prepared by RCC Umweltchemie Ag. 114 p.
UCB Chemicals Corp. (1995) Submission of Toxicity Data in Support of the
Registration of Thiram 75 W. Transmittal of 1 Study.
McGaughey, B.; Carlock, L. (1995) Inhalation Hazard of Thiram 75 W. Unpublished
study prepared by Compliance Services Int'l. 7 p.
204
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43741900
43741901
43757400
43757401
43759100
43759101
43762600
43762601
43762602
43787500
43787501
43813100
43813101
UCB Chemicals Corp. (1995) Submission of Metabolism Data in Support of the
Thiram Registration Standard. Transmittal of 1 Study.
Morgenroth, U.; Wyss-Benz, M. (1995) (Carbon 14)-Thiram: Plant Metabolism Study
in Field Grown Grapes: Lab Project Number: 319590. Unpublished study prepared by
RCC Umweltchemie AG. 135 p.
UCB Chemical Corp. (1995) Submission of Residue Data in Support of Thiram
Registration Standard. Transmittal of 1 Study.
Leppert, B. (1995) Magnitude of Thiram Residues in Apples: Final Report: Lab Project
Number: SARS-94-31: ML94-0458-UCB: SARS-94-CA-31A. Unpublished study
prepared by Stewart Agricultural Research Services, Inc. and Morse Labs, Inc. 441 p.
UCB Chemical Corp. (1995) Submission of Residue Chemistry Data in Support of the
Registration Standard for Thiram. Transmittal of 1 Study.
Leppert, B. (1995) Magnitude of Thiram Residues in Peaches: Final Report: Lab Project
Number: UCB 1994-32: ML94-0459-UCB: SARS-94-GA-32. Unpublished study
prepared by Stewart Agricultural Research Services, Inc. and Morse Labs, Inc. 208 p.
UCB Chemical Corp. (1995) Submission of Residue Chemistry Data in Support of the
Registration Standard for Thiram. Transmittal of 2 Studies.
Leppert, B. (1995) Magnitude of Thiram Residues in Strawberries: Final Report: Lab
ProjectNumber: UCB 1993-02: SARS-93-MI-52: SARS-93-NY-52. Unpublished study
prepared by Stewart Agricultural Research Services, Inc. and Morse Labs, Inc. 430 p.
Leppert, B. (1995) Magnitude of Thiram Residues in Strawberries: Final Report: Lab
ProjectNumber: UCB 1994-30: SARS-94-CA-30A: SARS-94-CA-30B. Unpublished
study prepared by Stewart Agricultural Services, Inc. and Morse Labs, Inc. 424 p.
UCB Chemicals Corp. (1995) Submission of Environmental Fate Data in Support of the
Thiram Registration Standard. Transmittal of 1 study.
Morgenroth, U. (1995) Adsorption/Desorption of (carbon 14)Thiram on Four Soils: Lab
Project Number: 354780. Unpublished study prepared by RCC Umweltchemie AG. 80
P-
UCB Chemical Corp. (1995) Submission of Residue Chemistry Data in Support of the
Registration Standard for Thiram. Transmittal of 1 Study.
Leppert, B. (1995) Magnitude of Thiram Residues in Apples: Final Report: Lab Project
205
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43835200
43835201
43835202
43835203
43835204
43835205
43835206
43835207
43835208
43835209
Number: ML93-0437-UCB: SARS-93-50: UCB 1993-01. Unpublished study prepared
by Stewart Agricultural Research Services, Inc. and Morse Labs, Inc. 554 p.
Thiram Task Force II (1995) Submission of Residue Data in Support of the Thiram
Registration Standard. Transmittal of 10 Studies.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in Dry
Beans: Lab Project Number: 94-016: 943G8: HWI 6456-113. Unpublished study
prepared by Corning Hazleton, Inc. and Gustafson, Inc. 261 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in Sweet
Corn: Lab Project Number: 94-015: 943G7: HWI 6456-112. Unpublished study
prepared by Corning Hazleton, Inc. and Gustafson, Inc. 198 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in Green
Onions: Lab Project Number: 94-009: 94130: HWI 6456-105. Unpublished study
prepared by Corning Hazleton, Inc. and Gustafson, Inc. 358 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in Bulb
Onions: Lab Project Number: 94-001: 94129: HWI 6456-104. Unpublished study
prepared by Corning Hazleton, Inc. and Gustafson, Inc. 385 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Cotton Fractions: Lab Project Number: HWI 6456-107: 94123: 94-002.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc. 223 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Field Corn Fractions: Lab Project Number: HWI 6456-110: 94124: 94-003.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc.
202 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Safflower Fractions: Lab Project Number: HWI 6456-106: 94125: 94-004.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc.
231 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Soybean Fractions: Lab Project Number: HWI 6456-108: 94127: 94-005.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc. 201 p.
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Sugar Beet Fractions: Lab Project Number: HWI 6456-109: 94126: 94-006.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc.
213 p.
206
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43835210
43846300
43846301
43974900
43974901
44084100
44084101
44086100
44086101
44180100
44180101
44272100
44272101
44292100
Shen, S. (1995) Determination of the Residues of Thiram and Its Metabolite in
Processed Wheat Fractions: Lab Project Number: HWI6456-111: 94128: 94-007.
Unpublished study prepared by Corning Hazleton, Inc. and Gustafson, Inc. 248 p.
UCB Chemicals Corp. (1995) Submission of Residue Data in Support of the Thiram
Registration Standard. Transmittal of 1 Study.
Leppert, B. (1995) Magnitude of Thiram Residues in Apples, A Processing Study: Final
Report: Lab Project Number: UCB 1993-003: SARS-93-NY-51: 93405. Unpublished
study prepared by Stewart Agricultural Research Services, Inc. 326 p.
UCB Chemicals Corp. (1996) Submission of Environmental Fate Data in Support of the
Tetramethylthiruam (Thiram) Registration Standard. Transmittal of 1 Study.
Wyss-Benz, M. (1996) (Carbon- 14)-Thiram: Confined Rotational Crop Study: Lab
Project Number: 378123: RCC 378123. Unpublished study prepared by RCC
Umweltchemie Ag. 117 p.
UCB Chemicals Corp. (1996) Submission of Toxicity Data in Support of the
Registration of Thiram 75W. Transmittal of 1 Study.
Carlock, L. (1996) Thiram 75 W: Acute Oral Toxicity in Rats. Unpublished study
prepared by UCB Chemicals. 6 p.
UCB Chemicals Corp. (1996) Submission of Hazard to Non-Target Plants Data in
Support of the Thiram Registration Standard. Transmittal of 1 Study.
Coates, M. (1996) Thiram: Algal Growth Inhibition: Addendum to MRID 426460-01:
Lab Project Number: UCB 442/960953: UCB 442/921255. Unpublished study
prepared by Huntingdon Life Sciences, Ltd. 10 p.
Gustafson, Inc. (1996) Submission of Toxicity Data in Support of the Application for
Registration of FA12 Thiram Seed Treatment Fungicide. Transmittal of 1 Study.
Kuhn, J. (1994) Dermal Sensitization Study in Guinea Pigs: DNCB C-3762: (Positive
Control Data): Lab Project Number: 0620-93. Unpublished study prepared by
Stillmeadow, Inc. 16 p.
Gustafson, Inc. (1997) Submission of Product Chemistry Data in Support of the
Registration of Raxil-Thiram Flowable Fungicide. Transmittal of 1 Study.
Mote, J.; Dempsay, A. (1996) Product Chemistry Data: Raxil Thiram Flowable
Fungicide: Amended Report: Lab Project Number: M104:76-l. Unpublished study
prepared by Gustafon, Inc. 85 p.
Gustafson, Inc. (1997) Submission of Product Chemistry Data in Support of the
207
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Registration of Raxil-Thiram Flowable Fungicide. Transmittal of 1 Study.
44292101 Mote, J.; Dempsay, A. (1996) Product Chemistry Data: Raxil Thiram Flowable
Fungicide: Amended Report: Lab Project Number: M104:76-l. Unpublished study
prepared by Gustafson, Inc. 85 p.
44303200 Gustafson, Inc. (1997) Submission of Toxicity Data in Support of the Registration of
42-S Thiram Fungicide. Transmittal of 1 Study.
44303201 Bennick, J. (1997) Acute Inhalation Toxicity Study in Rats: 42-S Thiram Fungicide:
Final Report: Lab Project Number: 3275-97: S9-FF81-3.G4. Unpublished study
prepared by
Stillmeadow, Inc. 31 p.
44310600 Thiram Task Force II (1997) Submission of Toxicity Data in Support of the
Registration for Thiram. Transmittal of 1 Study.
44310601 Hiles, R. (1990) Bioavailability Study in Male Rats with a (carbon 14)-Thiram-Treated
Diet: Final Report: Lab Project Number: 6111-131: 357-106: HLA 6111-131.
Unpublished study prepared by Hazleton Laboratories America, Inc. 89 p.
44381100 Trace Chemicals, Inc. (1997) Submission of Product Chemistry Data in Support of
Application for Amended Registration of TCI Protector-D Seed Treatment. Transmittal
of 1 Study.
44381101 Hartman, J. (1997) TCI Protector-D Seed Treatment: Product Chemistry. Unpublished
study prepared by Trace Chemicals, Inc. 7 p.
44458800 Uniroyal Chemical Co., Inc. (1998) Submission of Toxicity Data in Support of the
Registration of Vitavax 200FF. Transmittal of 1 Study.
44458801 Allan, S. (1997) Report Amendment to Vitavax 200FF: Acute Oral Toxicity to the Rat:
Lab Project Number: 911001D/URL 81/AC. Unpublished study prepared by
Huntingdon Life Science. 14 p.
44550800 UCB Chemicals Corp. (1998) Submission of Product Chemistry, Toxicity and Residue
Data in Support of the Reregistration of Thiram. Transmittal of 16 Studies.
44550801 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Acute Oral Toxicity in Rats:
Lab Project Number: 97711. Unpublished study prepared by Compliance Services
International. 6 p.
44550802 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Acute Dermal Toxicity in
Rabbits: Lab Project Number: 97712. Unpublished study prepared by Compliance
Services International. 6 p.
208
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44550803 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Acute Inhalation Toxicity in
Rats: Lab Project Number: 97713. Unpublished study prepared by Compliance Services
International. 7 p.
44550804 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Primary Eye Irritation in
Rabbits: Lab Project Number: 97714. Unpublished study prepared by Compliance
Serviceslnternational. 6 p.
44550805 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Primary Skin Irritation in
Rabbits: Lab Project Number: 97715. Unpublished study prepared by Compliance
Services International. 6 p.
44550806 Carlock, L. (1997) Thiram 65 Wettable Powder Fungicide: Dermal Sensitization in
Guinea Pigs: Lab Project Number: 97716. Unpublished study prepared by Compliance
Services
International. 6 p.
44550807 Kliskey, E. (1997) Determination of the Magnitude of Residues of Thiram in Pear
RAC's from Trees Treated with a Thiram 75% Water-Dispersible Granule Formulation:
Lab Project Number: 96003: ML96-0596-UCB. Unpublished study prepared by
Compliance Services International. 256 p.
44550808 Jacobson, S. (1997) Thiram 75W~Product Chemistry Volume I: Product Identity and
Composition, Description of Materials Used to Produce the Product, Description of
Production Process, Description of Formulation Process and Discussion of Formation
of Impurities: Amended Final Report: Lab Project Number: 96712. Unpublished study
prepared by Compliance Services International. 52 p. {OPPTS 830.1550, 830.1600,
830.1620, 830.1650, 830.1670}
44550809 Jacobson, S. (1997) Thiram 75W—Product Chemistry Volume II: Preliminary Analysis,
Certified Limits and Enforcement Analytical Method: Lab Project Number: 96713.
Unpublished study prepared by Compliance Services International. 114 p. {OPPTS
830.1700, 830.1750, 830.1800}
44550810 Jacobson, S. (1997) Thiram 75W—Product Chemistry Volume III: Product Properties:
Color, Physical State, Odor, Oxidizing or Reducing Action, Explodability, Storage
Stability of Product, Corrosion Characteristics, pH of Water Solutions or Suspensions,
and Density/Relative Density: Lab Project Number: 96714: 457/3. Unpublished study
prepared by Compliance Services International. 105 p. {OPPTS 830.6302, 830.6303,
830.6304, 830.6314, 830.6316, 830.6317, 830.6320, 830.7000, 830.7300}
44550811 Willis, C. (1997) Physical and Chemical Characteristics of Thiram Technical:
Determination of Stability: Lab Project Number: 1180-03: 97018. Unpublished study
prepared by Case Consulting Labs., Inc. 17 p. {OPPTS 830.6313}
209
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44550813
44550814
44550815
44550816
44607300
44607301
44607302
44607303
44607304
Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in Grape
RAC's from Vines Treated with a Thiram 75% Water-Dispersible Granule Formulation:
Lab Project Number: 96006: METH-7: ML96-0599-UCB. Unpublished study prepared
by Compliance Services International. 260 p.
Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in Grape
Processed Fractions Resulting from Applications of a Thiram 75% Water-Dispersible
Granule Formulation: Lab Project Number: 96007: ML96-0600-UCB. Unpublished
study prepared by Compliance Services International. 209 p.
Kliskey, E. (1997) Determination of the Magnitude of Residues of Thiram in Peach
RAC's From Trees Treated with a Thiram 75% Water-Dispersible Granule
Formulation: Lab Project Number: 96004: GL-13B: ML96-0597-UCB. Unpublished
study prepared by Compliance Services International. 235 p.
Kemman, R. (1997) Determination of the Magnitude of Residues of Thiram in
Nectarine RAC's From Trees Treated with a Thiram 75% Water-Dispersible Granule
Formulation: Lab Project Number: 96005: ML96-0598-UCB: METH-7. Unpublished
study prepared by Compliance Services International. 188 p.
Kemman, R. (1997) Determination of the Magnitude of Residues of Thiram in
Strawberry RAC's From Plants Treated with a Thiram 75% Water-Dispersible Granule
Formulation: Lab Project Number: 96008: ML96-0601-UCB: METH-7. Unpublished
study prepared by Compliance Services International. 310 p.
Big Bucks Enterprises (1998) Submission of Product Chemistry, Toxicity, and Efficacy
Data in Support of the Application for Registration of Deer Stopper. Transmittal of 11
Studies.
Messina, J. (1998) Formulating Process for Deer Stopper. Unpublished study prepared
by Big Bucks Enterprises. 5 p.
Messina, J. (1998) Formation of Impurities for Deer Stopper. Unpublished study
prepared by Big Bucks Enterprises. 5 p.
Sinning, D. (1998) Deer Stopper: Preliminmary Analysis: Lab Project Number: 1680-
03. Unpublished study prepared by Case Consulting Laboratories, Inc. lip.
(OPPTS 830.1700)
Sinning, D. (1958) Physical and Chemical Characteristics of Deer Stopper: Color,
Physical State, Odor, pH, Viscosity and Relative Density: Lab Project Number: 1680-
01. Unpublished study prepared by Case Consulting Laboratories, Inc. 9 p. {OPPTS
830.6302,830.6303, 830.6304, 830.7000, 830.7100, 830.7300}
210
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44607311
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44724501
Cerven, D. (1998) Single Dose Oral Toxicity in Rats/LD 50 in Rats: Deer Stopper: Lab
Project Number: MB 97-6474.01: 67-04. Unpublished study prepared by MB Research
Laboratories, Inc. 12 p.
Cerven, D. (1998) Acute Dermal Toxicity in Rabbits/LD 50 on Rabbits: Deer Stopper:
Lab Project Number: MB 97-6474.02: 175-04. Unpublished study prepared by MB
Research Laboratories, Inc. 14 p.
Cerven, D. (1998) Acute Inhalation Toxicity in Rats/LC 50 in Rats: Deer Stopper: Lab
Project Number: MB 97-6474.05: 318-10. Unpublished study prepared by MB
Research Laboratories, Inc. 20 p.
Cerven, D. (1998) Primary Eye Irritation/Corrosion in Rabbits: Deer Stopper: Lab
Project Number: MB 97-6474.04: 236-04. Unpublished study prepared by MB
Research Laboratories, Inc. 12 p.
Kieffer, L. (1998) Primary Dermal Irritation in Rabbits: Deer Stopper: Lab Project
Number: MB 97-6474.03: 166-05. Unpublished study prepared by MB Research
Laboratories, Inc. 10 p.
Nolte, D. (1998) Efficacy of Selected Repellent to Deter Deer Brownsing (sic) of
Conifer Seedlings: Deer Stopper. Unpublished study prepared by USD A/APHIS
National Wildlife Research Center. 16 p.
Hoff, T. (1998) Delayed Contact Dermal Sensitization Test-Buehler Method
(in Guinea Pigs): Deer Stopper: Lab Project Number: MB 97-6474.06: 112B-03.
Unpublished study prepared by MB Research Laboratories, Inc. 13 p.
Big Bucks Enterprises (1998) Submission of Efficacy Data in Support of the
Application for Registration of Deer Stopper. Transmittal of 1 Study.
Armstrong, J.; Causey, M.; Owen, J. (1998) Efficacy to Deer Stopper Repellent for
Reducing White-Tailed Deer Damage to Ornamental Plantings. Unpublished study
prepared by Auburn University. 10 p.
UCB Chemicals Corp. (1998) Submission of Residue Data in Support of the
Reregistration of the Thiram Containing Products Spotrete 75 WDG, Thiram 75%
Water-Dispersible Granule Formulation and Thiram 65% Wettable Powder
Formulation. Transmittal of 5 Studies.
Dykeman, R. (1998) Determination of the Dissipation of Residues of Thiram in
California Turf and Bare Ground Plots Treated with Spotrete 75WDG: Lab Project
Number: 95049: F96318-810: 95049-CA1. Unpublished study prepared by Compliance
Services International. 818 p.
211
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44784500
44784501
44784502
44784503
44784504
Dykeman, R. (1998) Determination of the Dissipation of Residues of Thiram in North
Carolina Turf and Bare Ground Plots Treated with Spotrete 75WDG: Lab Project
Number: 95051: 95051-NCI: F96194-054. Unpublished study prepared by
Compliance Services International. 1322 p.
Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in Peach
RAC's from Trees Treated with a Thiram 75% Water-Dispersible Granule Formulation:
Lab Project Number: 97003: ML97-0682-UCB: 97003-LA1. Unpublished study
prepared by Compliance Services International. 239 p. {OPPTS 860.1500}
Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in
Strawberry RAC's from Plants Treated with a Thiram 75% Water-Dispersible Granule
Formulation and Selectively with a Thiram 65% Wettable Powder Formulation: Lab
Project Number: 97006: ML97-0685-UCB: 97006-CA1. Unpublished study prepared
by Compliance Services International. 451 p. {OPPTS 860.1340}
Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in Apple
RAC's from Trees Treated with a Thiram 75% Water-Dispersible Granule Formulation:
Lab Project Number: 97001: ML97-0680-UCB: 96001. Unpublished study prepared by
Compliance Services International. 249 p. {OPPTS 860.1340}
Trace Chemicals LLC (1999) Submission of Product Chemistry and Toxicity Data in
Support of the Application for Registration of TCI Protector L-M Seed Treatment.
Transmittal of 7 Studies.
Hartman, J. (1998) TCI Protector L-M Seed Treatment: Product Chemistry for End-Use
Product: Lab Project Number: TMM-98. Unpublished study prepared by Trace
Chemical, Inc. 85 p. {OPPTS 830.1550, 830.1600, 830.1650, 830.1670, 830.1750,
830.1800, 830.6302, 830.6303, 830.6304, 830.6317, 830.6320, 830.7000, 830.7100,
830.7300}
Kuhn, J. (1998) Thiram-Metalaxyl-Moly FL: Acute Oral Toxicity Study in Rats: Final
Report: Lab Project Number: 4393-98. Unpublished study prepared by Stillmeadow,
Inc. 17 p.
Kuhn, J. (1998) Thiram-Metalaxyl-Moly FL: Acute Dermal Toxicity Study in Rabbits:
Final Report: Lab Project Number: 4391-98. Unpublished study prepared by
Stillmeadow, Inc.
14 p.
Bennick, J. (1998) Thiram-Metalaxyl-Moly FL: Acute Inhalation Toxicity Study in
Rats: Final Report: Lab Project Number: 4395-98. Unpublished study prepared by
Stillmeadow, Inc. 19 p.
212
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44801401
44801402
44801403
44801404
44801405
44801406
44801407
Kuhn, J. (1998) Thiram-Metalaxyl-Moly-FL: Primary Eye Irritation Study in Rabbits:
Final Report: Lab Project Number: 4396-98. Unpublished study prepared by
Stillmeadow, Inc. 18 p.
Kuhn, J. (1998) Thiram-Metalaxyl-Moly-FL: Primary Dermal Irritation Study in
Rabbits: Final Report: Lab Project Number: 4397-98. Unpublished study prepared by
Stillmeadow, Inc. 14 p.
Kuhn, J. (1998) Thiram-Metalaxyl-Moly FL: Dermal Sensitization Study in Guinea
Pigs: Final Report: Lab Project Number: 4398-98. Unpublished study prepared by
Stillmeadow, Inc. 19 p.
Trace Chemicals, Inc. (1999) Submission of Product Chemistry and Toxicity Data in
Support of the Application for Registration of Vitavax-Thiram-Metalaxyl Flowable
Liquid. Transmittal of 7 Studies.
Hartman, J. (1998) TCI Vitavax-Thiram-Metalaxyl FL Seed Treatment: Product
Chemistry: Lab Project Number: VTM-98. Unpublished study prepared by Trace
Chemicals, Inc. 90 p. {OPPTS 830.1550, 830.1600, 830.1650, 830.1700, 830.1750,
830.6303, 830.6303,830.7220, 830.7950, 830.7300}
Kuhn, J. (1998) Acute Oral Toxicity Study in Rats: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4538-98. Unpublished study
prepared by Stillmeadow, Inc. 13 p.
Kuhn, J. (1998) Acute Dermal Toxicity Study in Rabbits: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4539-98. Unpublished study
prepared by Stillmeadow, Inc. 14 p.
Bennick, J. (1998) Acute Inhalation Toxicity Study in Rats: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4540-98. Unpublished study
prepared by Stillmeadow, Inc. 19 p. {OPPTS 870.1300}
Kuhn, J. (1998) Primary Eye Irritation Study in Rabbits: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4541-98. Unpublished study
prepared by Stillmeadow, Inc. 18 p.
Kuhn, J. (1998) Primary Dermal Irritation Study in Rabbits: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4542-98. Unpublished study
prepared by Stillmeadow, Inc. 14 p.
Kuhn, J. (1998) Dermal Sensitization Study in Guinea Pigs: Vitavax-Thiram-Metalaxyl
Flowable Liquid: Final Report: Lab Project Number: 4543-98. Unpublished study
213
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prepared by Stillmeadow, Inc. 19 p. {OPPTS 870.2600}
44802800
44802801
44840700
44840701
44855700
44855701
44875600
44875601
44909700
44909701
44957400
44957401
Prochimie International, Inc. (1999) Submission of Product Chemistry Data in Support
of the Reregistration of the Thiram Containing Product Thiram Technical. Transmittal
of 1 Study.
Roston, A. (1999) Product Identity, Composition, and Physical/Chemical Properties of
Thiram: Thiram Product Chemistry: Chemical Code 079801: Lab Project Number:
THIRAM PRODUCT CHEMISTRY. Unpublished study prepared by Prochimie
International Inc. 43 p.
Big Bucks Enterprises (1999) Submission of Product Chemistry Data in Support of the
Application for Registration of Deer Stopper Deer Repellent. Transmittal of 1 Study.
Sinning, D. (1999) Physical and Chemical Characteristics of Deer Stopper: Storage
Stability and Corrosion Characteristics: 12 Month at Room Temperature: Lab Project
Number: 1680-02. Unpublished study prepared by Case Consulting Laboratories, Inc.
11 p. {OPPTS 830.6317, 830.6320}
Thiram Task Force II (1999) Submission of Pesticide Usage Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
Thompson, R. (1999) Thiram Seed Treatments in the United States. Unpublished study
prepared by Doane Marketing Research, Inc. 57 p.
Gustafson LLC (1999) Submission of Residue Chemistry Data in Support of the
Petition for Tolerance of Carboxin in/on Canola and the Registration of Vitaflo 280
Flowable Fungicide. Transmittal 1 Study.
McFadden, P. (1999) Determination of Residues of Carboxin in the Raw Agricultural
Commodities and the Processed Commodities of Canola: Lab Project Number: 98-002:
98410: 130.001. Unpublished study prepared by Gustafson Research and Development
Center and North Coast Laboratories, Ltd. 285 p.
UCB Chemicals (1999) Submission of Pesticide Use Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
Thompson, R. (1999) Thiram Foliar Treatments in the United States. Unpublished
study prepared by UCB Chemicals. 75 p.
Gustafson LLC (1999) Submission of Residue Chemistry Data in Support of the
Registration of Vitaflo 280 Flowable Fungicide. Transmittal of 1 Study.
McFadden, P. (1999) Determination of Residues of Carboxin in the Raw Agricultural
214
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Commodities and Processed Commodities of Canola: Vitaflo 280 Flowable Fungicide:
Lab Project Number: 98-002: 98410: 130.001. Unpublished study prepared by
Gustafson Research and Development Center North Coast Labs., Ltd. 373 p.
44992500 UCB Chemical Corp. (1999) Submission of Residue Chemistry Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study
44992501 Kang, H.; Robinson, R. (1999) Metabolic Fate and Distribution of (carbon-14) Thiram
in Apple: Lab Project Number: R369801: XBL98041: RPT00519. Unpublished study
prepared by Xenobiotic Labs, Inc. 427 p. {OPPTS 860.1300}
45042800 Aventis CropScience (2000) Submission of Product Chemistry and Toxicity Data in
Supportof the Application for Registration of Charter Brand PB Fungicide. Transmittal
of 7 Studies.
45042801 Cookinham, J. (1999) EXP 81096A Product Chemistry: Lab Project Number:
310003.1.001. Unpublished study prepared by MidWest Research Institute. 140 p.
45042802 Kern, T. (1999) Acute Oral Toxicity Study of EXP 81096A in Albino Rats: Final
Report: Lab Project Number: WIL-21187. Unpublished study prepared by WIL
Research Labs., Inc. 38 p. {OPPTS 870.1100}
45042803 Kern, T. (1999) Acute Dermal Toxicity Study of EXP 81096A in Albino Rats: Final
Report: Lab Project Number: WIL-21188. Unpublished study prepared by WIL
Research Labs., Inc.40 p. {OPPTS 870.1200}
45042804 Ulrich, C. (1999) Acute Inhalation Toxicity Study of EXP 81096A in Albino Rats:
Final Report: Lab Project Number: WIL-21186. Unpublished study prepared by WIL
Research Labs., Inc. 68 p. {OPPTS 870.1300}
45042805 Kern, T. (1999) Acute Eye Irritation Study of EXP 81096A in Albino Rabbits: Final
Report: Lab Project Number: WIL-21190. Unpublished study prepared by WIL
Research Labs., Inc. 22 p. {OPPTS 870.2400}
45042806 Kern, T. (1999) Acute Dermal Irritation Study of EXP 81096A in Albino Rabbits: Final
Report: Lab Project Number: WIL-21189. Unpublished study prepared by WIL
Research Labs., Inc. 22 p. {OPPTS 870.2500}
45042807 Kern, T. (1999) Skin Sensitization Study of EXP 81096A in Albino Guinea Pigs: Final
Report: Lab Project Number: WIL-21191. Unpublished study prepared by WIL
Research Labs., Inc. 52 p. {OPPTS 870.2600}
45205402 Smudin, D. (2000) Determination of Carboxin Residues on Raw and Processed Rice
Fractions from Rice Grown from Seed Treated with VITAVAX-200
FlowableFungicide: Lab Project Number: 96509: CLS-96-104: STBR-96-RI-16.
Unpublished study prepared
215
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by Gustafson R&D Center, CLP Contract Field Research, and South Texas Ag
Research. 657 p.
45228600 Uniroyal Chemical Company, Inc. (2000) Submission of Environmental Fate Data in
Support of the Registration of A815 Technical, Terraclor Technical, Terraclor
Technical 96 and Optima 4F. Transmittal of 2 Studies.
45228602 Blaszczynski, E. (2000) Analytical Method for Determination of Thiram in Pond
Water: Lab Project Number: RL-12: AC-7004: 99188. Unpublished study prepared by
Uniroyal Chemical Company, Inc. 61 p. {OPPTS 850.7100}
45243400 UCB Chemicals Corporation (2000) Submission of Environmental Fate Data in
Support of the Reregistration of Thiram. Transmittal of 1 Study.
45243401 Wyss-Benz, M. (1992) Degradation and Metabolism of Thiram in Aquatic Systems
(Amended Report): Lab Project Number: 303456. Unpublished study prepared by RCC
Umweltchemie Ag. 156 p.
45248600 Gustafson LLC. (2000) Submission of Product Chemistry Data in Support of the
Registration of Raxil-Thiram Flowable Fungicide. Transmittal of 1 Study.
45248601 Dunn, N. (2000) Validation of a Method for the Determination of Tebuconazole and
Thiram in Raxil Thiram Flowable Fungicide by High Performance Liquid
Chromatography: Final Report: Lab Project Number: GRL-11725: 2000-001.
Unpublished study prepared by Uniroyal Chemical Co. 40 p.
45268600 Gustafson LLC (2000) Submission of Product Chemistry and Toxicity Data in Support
of the Application for Registration of Gaucho CS Flowable. Transmittal of 9 Studies.
45268601 Dunn, N. (2000) Validation of a Method for the Determination of Imidacloprid,
Carbathiin and Thiram in Gaucho CS FL By High Performance Liquid
Chromatography: Final Report: Lab Project Number: 2000-002: GRL-11744: GRL-FR-
11744. Unpublished study prepared by Uniroyal Chemical Co. 43 p.
45268602 McFadden, P. (2000) The Physical Characteristics of Gaucho CS Flowable End-Use
Product: Lab Project Number: PC/00-006. Unpublished study prepared by Gustafson
Research and Development Center. 102 p. {OPPTS 830.1550, 830.1600, 830.1620,
830.1670, 830.1750, 830.6302, 830.6304, 830.7300, 830.7100}
45268603 Dunn, N. (2000) The Oxidizing and Reducing Characteristics of Gaucho CS FL: Final
Product: Lab Project Number: GRL-11750: 2000-008: GRL-FR-11750. Unpublished
study prepared by Uniroyal Chemical Co. 26 p. {OPPTS 830.6314}
45268604 Merkel, D. (2000) Acute Oral Toxicity Study in Rats-Defined LD50: Gaucho CS FL:
Lab Project Number: 9533: P320. Unpublished study prepared by Product Safety Labs.
23 p. {OPPTS 870.1100}
216
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45268605 Merkel, D. (2000) Acute Dermal Toxicity Study in Rats-Limit Test: Gaucho CS FL:
Lab Project Number: 9534: P322. Unpublished study prepared by Product Safety Labs.
15 p. {OPPTS 870.1200}
45268606 Merkel, D. (2000) Acute Inhalation Toxicity Study in Rats-Limit Test: Gaucho CS FL:
Lab Project Number: 9535: P330. Unpublished study prepared by Product Safety Labs.
22 p. {OPPTS 870.1300}
45268607 Merkel, D. (2000) Primary Eye Irritation Study in Rabbits: Gaucho CS FL: Lab Project
Number: 39536: P324. Unpublished study prepared by Product Safety Labs. 16 p.
{OPPTS 870.2400}
45268608 Merkel, D. (2000) Primary Skin Irritation Study in Rabbits: Gaucho CS FL: Lab Project
Number: 9537: P326. Unpublished study prepared by Product Safety Labs. 15 p.
{OPPTS 870.2500}
45268609 Merkel, D. (2000) Dermal Sensitization Study in Guinea Pigs (Buehler Method):
Gaucho CS FL: Lab Project Number: 9538: P328. Unpublished study prepared by
Product Safety Labs. 24 p. {OPPTS 870.2600}
45391800 Aventis CropScience (2001) Submission of Product Chemistry and Toxicity Data in
Support of the Application for the Registration of Foundation Lite. Transmittal of 7
Studies.
45391801 Zhao, Z. (2000) Foundation Lite Product Chemistry: Lab Project Number: 484.
Unpublished study prepared by Aventis Environmental Science. 180 p. {OPPTS
830.1550, 830.1750, 830.1600, 830.1650, 830.1670, 830.1700, 830.1800, 830.6302,
830.6303, 830.6304, 830.7300, 830.7000, 830.6314, 830.6315, 830.7100}
45391802 Kern, T. (1998) Acute Oral Toxicity Study of Foundation Lite in Albino Rats: Lab
Project Number: WIL-21147. Unpublished study prepared by WIL Research
Laboratories, Inc. 40 p. {OPPTS 870.1100}
45391803 Kern, T. (1999) Acute Dermal Toxicity Study of Foundation Lite in Albino Rats: Lab
Project Number: WIL-21148. Unpublished study prepared by WIL Research
Laboratories, Inc. 42 p.{OPPTS 870.1200}
45391804 Ulrich, C. (1999) Acute Inhalation Toxicity Study of Foundation Lite in Albino Rats:
Lab Project Number: WIL-21146. Unpublished study prepared by WIL Research
Laboratories, Inc. 64 p.
45391805 Kern, T. (1999) Acute Eye Irritation Toxicity Study of Foundation Lite in Albino
Rabbits: Lab Project Number: WIL-21150. Unpublished study prepared by WIL
Research Laboratories, Inc. 22 p. {OPPTS 870.2400}
217
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45391806 Kern, T. (1999) Acute Dermal Irritation Toxicity Study of Foundation Lite in Albino
Rabbits: Lab Project Number: WIL-21149. Unpublished study prepared by WIL
Research Laboratories, Inc. 23 p. {OPPTS 870.2500}
45391807 Kern, T. (1999) Skin Sensitization Study of Foundation Lite in Guinea Pigs: Lab
Project Number: WIL-21151. Unpublished study prepared by WIL Research
Laboratories, Inc. 43 p.{OPPTS 870.2600}
45399500 UCB Chemical Corporation (2001) Submission of Residue Chemistry Data in Support
of the Reregistration of Thiram. Transmittal of 2 Studies.
45399501 Kemman, R. (1998) Determination of the Magnitude of Residues of Thiram in
Nectarine RAC's From Trees Treated with a Thiram 75% Water-DispersibleGranule
Formulation:Lab Project Number: 97004. Unpublished study prepared by Compliance
Services International. 200 p. {OPPTS 860.1340}
45399502 Kemman, R. (1997) Determination of the Magnitude of Residues of Thiram in
Nectarine RAC's from Trees Treated with a Thiram 75% Water Dispersible Granule
Formulation: Lab Project Number: 96005. Unpublished study prepared by Compliance
Services International 188 p.
45416300 Gustafson LLC. (2001) Submission of Product Chemistry, Residue, Toxicity, Risk
Assessment and Exposure Data in Support of the Application for Registration of Titan
FL. Transmittal of 14 Studies.
45416301 McFadden, P. (2001) The Physical Characteristics of RTU TI435 End-Use Product:
Titan FL: Lab Project Number: PC/01-004. Unpublished study prepared by Gustafson
Research and Development Center. 130 p. {OPPTS 830.1550, 830.1600, 830.1650,
830.1670, 830.1750, 830.6302, 830.6303, 830.6304, 830.7300, 830.7000, 830.7100}
45416302 Dunn, N. (2001) The Oxidizing and Reducing Characteristics of GUS 7047-01: Final
Report: Lab Project Number: GRL-11798: 2000-011: GR-FR-11798. Unpublished
study prepared by Crompton Co. 23 p. {OPPTS 830.6314}
45416303 Dunn, N. (2001) Validation of a Method for the Determination of Metalaxyl in GUS
7047-01 by Gas Chromatography: Final Report: Lab Project Number: GRL-11797:
2000-010: GRL-FR-11797. Unpublished study prepared by Crompton Co. 33 p.
45416304 Dunn, N. (2001) Validation of a Method for the Determination of Clothiandan,
Carbathiin and Thiram in GUS 7047-01 by High Performance Liquid Chromatography:
Final Report: Lab Project Number: GRL-11796: 2000-009: GRL-FR-11796.
Unpublished study prepared by Crompton Co. 39 p.
45416305 Merkel, D. (2001) Acute Oral Toxicity Study in Rats—Limit Test: GUS 7047-01: Lab
Project Number: 9876: P320. Unpublished study prepared by Product Safety Labs. 14 p.
{OPPTS 870.1100}
218
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45416306 Merkel, D. (2001) Acute Dermal Toxicity Study in Rats—Limit Test: GUS 7047-01:
Lab Project Number: 9877: P322. Unpublished study prepared by Product Safety Labs.
15 p. {OPPTS 870.1200}
45416307 Merkel, D. (2001) Acute Inhalation Toxicity Study in Rats—Limit Test: GUS 7047-01:
Lab Project Number: 9878: P330. Unpublished study prepared by Product Safety Labs.
22 p. {OPPTS 870.1300}
45416308 Merkel, D. (2001) Primary Eye Irritation Study in Rabbits: GUS 7047-01: Lab Project
Number: 9879: P324. Unpublished study prepared by Product Safety Labs. 16 p.
{OPPTS 870.2400}
45416309 Merkel, D. (2001) Primary Skin Irritation Study in Rabbits: GUS 7047-01: Lab Project
Number: 9880: P326. Unpublished study prepared by Product Safety Labs. 15 p.
{OPPTS 870.2500}
45416310 Merkel, D. (2001) Dermal Sensitization Study in Guinea Pig (Buehler Method):
GUS 7047-01: Lab Project Number: 9881: P328. Unpublished study prepared by
Product Safety Labs. 24 p. {OPPTS 870.2600}
45416311 McFadden, P. (2001) Determination of Residues of GUS 7025-01 in Canola: Lab
Project Number: 0004019: ADPEN-MI-0004019-1001. Unpublished study prepared by
Gustafson Research and Development Center and Adpen Labs., Inc. 505 p. {OPPTS
860.1340}
45416312 McFadden, D. (2001) Use and Occupational Exposure Information for Titan FL: Final
Report: Lab Project Number: 01-101. Unpublished study prepared by Gustafson LLC.
31 p.
45416313 McFadden, D. (2001) Environmental Chemistry and Fate of Titan FL: Final Report:
Lab Project Number: 01-102. Unpublished study prepared by Gustafson LLC. lip.
45416314 McFadden, D. (2001) Metabolism/Toxicokinetic Information for Titan FL: Final
Report: Lab Project Number: 01-103. Unpublished study prepared by Gustafson LLC. 8
P-
45430500 Gustafson LLC (2001) Submission of Efficacy and Toxicity Data in Support of the
Application for the Registration of Titan FL. Transmittal of 3 Studies.
45430501 McFadden, D. (2001) Final Report Titan FL (RTU TI435) Efficacy Trials: Lab Project
Number: 01-100. Unpublished study prepared by Gustafson LLC. 606 p.
45430502 McFadden, D. (2001) Final Report Tier in Summary for Titan FL: Lab Project
Number: 01-104. Unpublished study prepared by Gustafson LLC. 178 p.
219
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45430503 McFadden, D. (2001) Final Report Tier II Summary for Titan FL: Lab Project Number:
01-105. Unpublished study prepared by Gustafson LLC. 22 p.
45441200 Thiram Task Force II (2001) Submission of Toxicity and Fate Data in Support of the
Reregistration of Thiram Technical. Transmittal of 3 Studies.
45441201 Gallagher, S.; Martin, K.; Beavers, J. (2001) Thiram Technical: A Reproduction Study
with the Mallard: Final Report: Lab Project Number: 357-107. Unpublished study
prepared by Wildlife International, Ltd. 143 p.
45441202 Sutherland, C.; Kendall, T.; Krueger, H. (2001) Thiram Technical: A 7-Day Toxicity
Test with Duckweed (Lemna gibba G3): Final Report: Lab Project Number: 357A-101.
Unpublished study prepared by Wildlife International. Ltd. 79 p. {OPPTS 850.4400}
45441203 Turck, P. (1997) Two Generation Reproduction/Fertility Study in Rats with Thiram:
Lab Project Number: 399-180. Unpublished study prepared by MPI Research.
1579 p.
45490500 Gustafson (2001) Submission of Product Chemistry Data in Support of the Registration
of RAXIL-Thiram Flowable Fungicide. Transmittal of 1 Study.
45490501 Dunn, N. (2000) Validation of a Method for the Determination of Tebuconazole and
Thiram in Raxil Thiram Flowable Fungicide by High Performance Liquid
Chromatography: Lab Project Number: GRL-11725: 2000-001. Unpublished study
prepared by Uniroyal Chemical Co. 40 p.
45534700 EBDC/ETU Task Force (2001) Submission of Toxicity and Fate Data in Support of the
Reregistration of Ethylenebisdithiocarbamates and Other Dithiocarbamates. Transmittal
of 1 Study.
45534701 Lamb, IV, J.; Hentz, K.; Matthews, S.; et al. (2001) Analysis of Common Mechanisms
of Toxicity for Ethylenebisdithiocarbamates and Other Dithiocarbamates. Unpublished
study prepared by BBL Sciences. 111 p.
45556100 USEPA (2001) Submission of Toxicology, Environmental Fate, Residue, Risk and
Exposure, and Safety Data. Transmittal of 50 Studies.
45556146 Grey, W.; Marthre, D.; Rogers, S. (1983) Potential Exposure of Commercial Seed
Treating Applicators to the Pesticides Carboxin, Thiram and Lindane. Bulletin
Environmental Contamination and Toxicology 31(2):244-250.
45560300 UBC Chemicals (2001) Submission of Environmental Fate Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45560301 Menicks, D. (2001) Dissipation of Dislodgeable Foliar Residues of Thiram after
Application of Thiram 65% Wettable Powder to Strawberries in the USA: Lab Project
220
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Number: 1301: 1: 2. Unpublished study prepared by Agrisearch Incorporated. 123 p.
45587300 UCB Chemicals Corp. (2002) Submission of Residue Data in Support of the
Reregistration of Thiram Fungicide. Transmittal of 2 Studies.
45587301 Roland, L. (1996) HPLC Method for the Determination of Thiram in Fruits: Validation
of Some Critical Points. Unpublished study prepared by UCB Chemicals Corp. 22 p.
45587302 Roland, L. (1992) Thiram: Determination of Thiram in Fruits by High-performance
Liquid Chromatography. Unpublished study prepared by UCB Chemicals Corp.
22 p.
45589100 UCB Chemicals Corp. (2002) Submission of Toxicity Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45589101 Williams, J. (2001) Thiram: Acute Neurotoxicity Study in Rats: Lab Project Number:
AR7090: CTL/AR7090/REGULATORY/REPORT. Unpublished study prepared by
Central Toxicology Laboratory. 327 p. {OPPTS 870.6200}
45596100 UCB Chemicals Corp. (2002) Submission of Environmental Fate Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45596101 Shelper, K.; Runes, H. (2001) Photodegradation of (Carbon-14) Thiram in Sterilized
Buffer at pH 5 by Artificial Light: Lab Project Number: 1042W. Unpublished study
prepared by PTRL West, Inc. 116 p.
45651200 UCB Chemicals Co. (2002) Submission of Environmental Fate Data in Support of the
Reregistration for Thiram. Transmittal of 1 Study.
45651201 Shepler, K.; Runes, H. (2002) Photodegradation of (Carbon 14) Thiram in Sterilized
Buffer at pH 5 by Artificial Light: Lab Project Number: 1042W. Unpublished study
prepared by PTRL West, Inc. 117 p.
45651300 UCB Chemicals (2002) Submission of Residue Data in Support of the Reregistration of
Thiram. Transmittal of 1 Study.
45651301 Dykeman, R. (2002) Determination of the Magnitude of Residues of Thiram in Peach
RAC's From Trees Treated with a Thiram 75% Water-Dispersible Granule
Formulation: Lab Project Number: 01001. Unpublished study prepared by Compliance
Services International. 134 p. {OPPTS 860.1340}
45674500 Gustafson (2002) Submission of Product Chemistry Data in Support of the Application
for Registration of Gaucho CS Flowable. Transmittal of 5 Studies.
45674501 Brown, M. (2001) Determination of the Storage Stability and Corrosion Characteristics
of Gaucho CS FL in Blue HDPE Drums: Final Report: Lab Project Number: GRL-
221
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11745: 2000-003: GRL-FR-11745. Unpublished study prepared by Crompton Co. 43 p.
{OPPTS 830.6317, 830.6320}
45674502 Brown, M. (2001) Determination of the Storage Stability and Corrosion Characteristics
of Gaucho CS FL in Fluorinated HDPE Jugs: Final Report: Lab Project Number: GRL-
11746: 2000-004: GRL-FR-11746. Unpublished study prepared by Crompton Co. 43 p.
{OPPTS 830.6317, 830.6320}
45674503 Brown, M. (2001) Determination of the Storage Stability and Corrosion Characteristics
of Gaucho CS FL in Non-Fluorinated HDPE Jugs: Final Report: Lab Project Number:
GRL-11747: 2000-005: GRL-FR-11747. Unpublished study prepared by Crompton Co.
43 p. {OPPTS 830.6317, 830.6320}
45674504 Brown, M. (2001) Determination of the Storage Stability and Corrosion Characteristics
of Gaucho CS FL in Stainless Steel Totes: Final Report: Lab Project Number: GRL-
11748: 2000-006: GRL-FR-11748. Unpublished study prepared by Crompton Co. 45
p.{OPPTS 830.6317, 830.6320}
45674505 Brown, M. (2001) Determination of the Storage Stability and Corrosion Characteristics
of Gaucho CS FL in Plastic Totes: Final Report: Lab Project Number: GRL-11749:
2000-007: GRL-FR-11749. Unpublished study prepared by Crompton Co. 43 p.
{OPPTS 830.6317,
830.6320}
45695600 UCB Chemicals Corporation (2002) Submission of Toxicity Data in Support of the
Reregistration of Thiram. Transmittal of 2 Studies.
45695601 Wilkinson, C. (2002) The Acute Neurotoxicity of Thiram: Lab Project Number:
THIRAM-02-01: 02-01. Unpublished study prepared by C. Wilkinson LLC. 7 p.
45695602 Wilkinson, C. (2002) Thiram: Developmental Toxicity: Lab Project Number:
THIRAM-02-02: 02-02. Unpublished study prepared by C. Wilkinson LLC. 14 p.
45701500 UCB Chemicals Corporation (2002) Submission of Residue Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45701501 Dykeman, R. (2002) Determination of the Change in Magnitude of Thiram Residues on
Strawberry RAC's Upon Washing: Lab Project Number: 01003: ML02-1004-UCB:
METH-7. Unpublished study prepared by Compliance Services International,
University of Florida and Morse Laboratories, Inc. 110 p.
45714100 UCB Chemicals Corp. (2002) Submission of Environmental Fate Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45714101 Shepler, K.; Runes, H. (2002) Hydrolysis of (Carbon 14) Thiram at pH 5, 7, and 9: Lab
Project Number: 1041W. Unpublished study prepared by PTRL West, Inc.
222
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110 p.
45724500 UCB Chemicals Corp. (2002) Submission of Environmental Fate Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45724501 Shepler, K.; Runes, H. (2002) Photodegradation of (Carbon 14) Thiram in/on Soil by
Artificial Light: Lab Project Number: 1043W: 1043W-1: 1042W-004. Unpublished
study prepared by PTRL West, Inc. 115 p.
45736200 UCB Chemicals Corp. (2002) Submission of Residue Data in Support of the
Reregistration of Thiram. Transmittal of 1 Study.
45736201 Spanogle, T. (2002) Determination of Residues of Thiram After Application of Thiram
80WG (Containing 80% Thiram) in Apples in Germany: Lab Project Number: UCB-
THIRAM 2002-03: G00W004P: 20003003/G2-FPAP. Unpublished study prepared by
Arbeitsgemeinshaft GAB. 93 p. {OPPTS 860.1340 and 860.1520}
45750300 Gustafson LLC (2002) Submission of Product Chemistry Data in Support of the
Application for Registration of Titan FL. Transmittal of 5 Studies.
45750301 Vanstone, C. (2002) Determination of the Storage Stability and Corrosion
Characteristics of GUS 7047-01 in Blue HDPE Drums: 1 Year Study: Final Report: Lab
Project Number: GRL-11799: 2000-012: GRL-FR-11799. Unpublished study prepared
by Crompton Co. 43 p. {OPPTS 830.6317, 830.6320}
45750302 Vanstone, C. (2002) Determination of the Storage Stability and Corrosion
Characteristics of GUS 7047-01 in Florinated HDPE Jugs: 1 Year Study: Final Report:
Lab Project Number: GRL-11800: 2000-013: GRL-FR-11800. Unpublished study
prepared by Crompton Co. 43 p. {OPPTS 830.6317, 830.6320}
45750303 Vanstone, C. (2002) Determination of the Storage Stability and Corrosion
Characteristics of GUS 7047-01 in Non-Florinated HDPE Jugs: 1 Year Study: Final
Report: Lab Project Number: GRL-11801: 2000-014: GRL-FR-11801. Unpublished
study prepared by Crompton Co. 43 p. {OPPTS 830.6317, 830.6320}
45750304 Vanstone, C. (2002) Determination of the Storage Stability and Corrosion
Characteristics of GUS 7047-01 in Stainless Steel Totes: 1 Year Study: Final Report:
Lab Project Number: GRL-11802: 2000-015. Unpublished study prepared by Crompton
Co. 43 p. {OPPTS 830.6317, 830.6320}
45750305 Vanstone, C. (2002) Determination of the Storage Stability and Corrosion
Characteristics of GUS 7047-01 in Plastic Totes: 1 Year Study: Final Report: Lab
Project Number: GRL-11803: 2000-016. Unpublished study prepared by Crompton Co.
43 p. {OPPTS 830.6317, 83.6320}
45874300 Gustafson LLC (2003) Submission of Product Chemistry Data in Support of the
Amended Registration of Gustafson Thiram Technical. Transmittal of 1 Study.
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45874301 McFadden, D. (2003) Product Identity and Composition; Description of Materials Used
to Produce the Product; Description of Production Process; and Discussion of
Formation of Impurities: (Gustafson Thiram Technical): Final Report: Lab Project
Number: 03-100. Unpublished study prepared by Gustafson LLC. 49 p. {OPPTS
830.1550, 830.1600, 830.1620, 830.1670}
45880700 Gustafson LLC (2003) Submission of Product Chemistry Data in Support of the
Amended Registration of Gustafson Thiram Technical. Transmittal of 1 Study.
45880701 Sun, G. (2002) Preliminary Analysis and Storage Stability Test of Thiram Technical
Grade Active Ingredient: Final Report: Lab Project Number: 01.05951.01.002.
Unpublished study prepared by Southwest Research Institute. 26 p. {OPPTS 830.1700}
45926000 Crompton Manufacturing Company, Inc. (2003) Submission of Toxicity Data in
Support of the Registration of Vitaflo-280. Transmittal of 1 Study.
45926001 Dow, P. (2003) The In Vivo Dermal Absorption of (Carbon 14) Carboxin from Vitaflo-
280 in the Rat: Lab Project Number: 014756: 017456-1: 014756-0. Unpublished study
prepared by Ricerca Bioscience, LLC. 236 p. {OPPTS 870.7600}
46021300 Crompton Corporation (2003) Submission of Toxicity Data in Support of the
Reregistration of Vitavax. Transmittal of 1 Study.
46021301 Lengen, M. (2003) Compilation of Studies to Determine the Palatability and/or
Repellency of Carboxin Mixtures to Avian Species and Small Mammals. Project
Number: URO/013/984969, URO/013. Unpublished study prepared by The Crompton
Manufacturing Company, Inc. 93 p.
224
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Appendix E. GENERIC DATA CALL-IN
Note that a complete Data Call-in (DCI), with all pertinent instructions, will be sent to
registrants under separate cover.
225
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GDCI page 1 of 13
226
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GDCI page 2 of 13
227
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GDCI page 3 of 13
228
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GDCI page 4 of 13
229
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GDCI page 5 of 13
230
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GDCI page 6 of 13
231
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GDCI page 7 of 13
232
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GDCI page 8 of 13
233
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GDCI page 9 of 13
234
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Page 10 of 13
235
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Page 11 of 13
236
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Page 12 of 13
237
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Page 13 of 13
238
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Appendix F. PRODUCT SPECIFIC DATA CALL-IN
Note that a complete Data Call-in (DCI), with all pertinent instructions, will be sent to registrants
under separate cover.
239
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PDCI page 1 of 9
240
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PDCI page 2 of 9
241
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PDCI page 3 of 9
242
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PDCI page 4 of 9
243
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PDCI page 5 of 9
244
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PDCI Page 6 of 9
245
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PDCI Page 7 of 9
246
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PDCI Page 8 of 9
247
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PDCI Page 9 of 9
248
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Appendix G: EPA'S BATCHING OF THTRAM PRODUCTS FOR MEETING ACUTE TOXICITY
DATA REQUIREMENTS FOR REREGISTRATION
In an effort to reduce the time, resources and number of animals needed to fulfill the acute
toxicity data requirements for reregistration of products containing THIRAM as the active ingredient, the
Agency has batched products which can be considered similar for purposes of acute toxicity. Factors
considered in the sorting process include each product's active and inert ingredients (identity, percent
composition and biological activity), type of formulation (e.g., emulsifiable concentrate, aerosol, wettable
powder, granular, etc.), and labeling (e.g., signal word, use classification, precautionary labeling, etc.).
Note that the Agency is not describing batched products as "substantially similar" since some products
within a batch may not be considered chemically similar or have identical use patterns.
Using available information, batching has been accomplished by the process described in the
preceding paragraph. Notwith-standing the batching process, the Agency reserves the right to require, at
any time, acute toxicity data for an individual product should the need arise.
Registrants of products within a batch may choose to cooperatively generate, submit or cite a
single battery of six acute toxicological studies to represent all the products within that batch. It is the
registrants' option to participate in the process with all other registrants, only some of the other
registrants, or only their own products within a batch, or to generate all the required acute toxicological
studies for each of their own products. If a registrant chooses to generate the data for a batch, he/she
must use one of the products within the batch as the test material. If a registrant chooses to rely upon
previously submitted acute toxicity data, he/she may do so provided that the data base is complete and
valid by today's standards (see acceptance criteria attached), the formulation tested is considered by EPA
to be similar for acute toxicity, and the formulation has not been significantly altered since submission
and acceptance of the acute toxicity data. Regardless of whether new data is generated or existing data is
referenced, registrants must clearly identify the test material by EPA Registration Number. If more than
one confidential statement of formula (CSF) exists for a product, the registrant must indicate the
formulation actually tested by identifying the corresponding CSF.
In deciding how to meet the product specific data requirements, registrants must follow the
directions given in the Data Call-In Notice and its attachments appended to the RED. The DCI Notice
contains two response forms which are to be completed and submitted to the Agency within 90 days of
receipt. The first form, "Data Call-In Response," asks whether the registrant will meet the data
requirements for each product. The second form, "Requirements Status and Registrant's Response," lists
the product specific data required for each product, including the standard six acute toxicity tests. A
registrant who wishes to participate in a batch must decide whether he/she will provide the data or
depend on someone else to do so. If a registrant supplies the data to support a batch of products, he/she
must select one of the following options: Developing Data (Option 1), Submitting an Existing Study
(Option 4), Upgrading an Existing Study (Option 5) or Citing an Existing Study (Option 6). If a registrant
depends on another's data, he/she must choose among: Cost Sharing (Option 2), Offers to Cost Share
(Option 3) or Citing an Existing Study (Option 6). If a registrant does not want to participate in a batch,
the choices are Options 1, 4, 5 or 6. However, a registrant should know that choosing not to participate
in a batch does not preclude other registrants in the batch from citing his/her studies and offering to cost
share (Option 3) those studies.
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Fifty three products were found which contain Thiram as the active ingredient. These products
have been placed into five batches and a "No Batch" category in accordance with the active and inert
ingredients and type of formulation. Furthermore, the following bridging strategies are deemed
acceptable for this chemical:
Batch 3: EPA Reg. No. 5481-308 may not cite data generated with EPA Reg. No. 5481-
311
No Batch: Each product in this Batch should generate their own data.
NOTE: The technical acute toxicity values included in this document are for informational purposes
only. The data supporting these values may or may not meet the current acceptance criteria.
Batch 1
EPA Reg. No.
% Active Ingredient
8236-02
98.5
45728-01
98.5
Batch 2
EPA Reg. No.
% Active Ingredient
1001-60
75.0
45728-21
75.0
51036-53
75.0
Batch 3
EPA Reg. No.
% Active Ingredient
5481-308
Thiram: 30
PCNB: 30
5481-311
Thiram: 10
PCNB: 10
Batch 4
EPA Reg. No.
% Active Ingredient
769-866
20.0
769-907
20.0
250
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Batch 5
EPA Reg. No.
% Active Ingredient
400-112
Thiram: 17.0
Carboxin: 17.0
400-116
Thiram: 17.0
Carboxin: 17.0
No Batch
EPA Reg. No.
% Active Ingredient
4-136
11.0
4-180
10.0
4-184
Thiram: 10.0
Methoxychlor: 5.0
264-499
Thiram: 4.04
Naohthalenacetamide: 0.20
264-672
Thiram: 12.5
Triticonazole: 1.25
358-105
20.0
400-92
Thiram: 37.5
Carboxin: 37.5
400-156
Thiram: 5.7
Carboxin: 5.7
400-434
42.0
400-435
Thiram: 50.0
Carboxin: 30.0
769-652
75.0
769-910
50.0
1381-162
Thiram: 12.62
Thiabendazole: 0.35
1381-163
Thiram: 11.54
Thiabendazole: 0.33
7501-14
42.0
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No Batch
EPA Reg. No.
% Active Ingredient
7501-17
30.0
7501-64
29.52
7501-80
Thiram: 15.3
Bavtan: 5.0
7501-105
50.0
7501-114
Thiram: 10.0
Carboxin: 10.0
7501-117
26.60
7501-121
14.66
7501-123
12.71
7501-125
23.05
7501-133
Thiram: 13.2
Carboxin: 14.9
7501-141
Thiram: 12.0
Carboxin: 14.0
Lindane: 8.0
7501-151
Thiram: 20.0
Raxil: 0.6
7501-187
Thiram: 7.0
Carboxin: 3.5
Imidacloprid: 21.0
7501-190
Thiram: 9.49
Carboxin: 4.43
Clothianidin: 9.49
7501-194
Thiram: 10.0
Carboxin: 10.0
Metalaxyl: 28.35
8660-25
75.0
9195-197
Thiram: 40.76
Triadimefon: 1.59
11625-01
35.0
252
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No Batch
EPA Reg. No.
% Active Ingredient
11715-341
7.0
19713-309
25.0
42056-02
12.41
42056-04
35.0
42056-10
14.29
42056-22
Thiram: 14.29
Metalaxyl: 1.61
42056-23
Thiram: 10.0
Carboxin: 10.0
Metalaxyl: 1.62
45728-24
65.0
45728-26
42.11
253
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254
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Appendix H. List of Registrants Sent this Data Call-In Notice
255
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256
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Appendix I. LIST OF AVAILABLE RELATED DOCUMENTS AND ELECTRONICALLY
AVAILABLE FORMS
Pesticide Registration Forms are available at the following EPA internet site:
http://www.epa.gov/opprd001/forms/.
Pesticide Registration Forms (These forms are in PDF format and require the Acrobat reader)
Instructions
1. Print out and complete the forms. (Note: Form numbers that are bolded can be filled out
on your computer then printed.)
2. The completed form(s) should be submitted in hardcopy in accord with the existing
policy.
3. Mail the forms, along with any additional documents necessary to comply with EPA
regulations covering your request, to the address below for the Document Processing
Desk.
DO NOT fax or e-mail any form containing 'Confidential Business Information' or
'Sensitive Information.'
If you have any problems accessing these forms, please contact Nicole Williams at (703)
308-5551 or by e-mail atwilliams.nicole@epamail.epa.gov.
The following Agency Pesticide Registration Forms are currently available via the internet:
at the following locations:
8570-1
Application for Pesticide
Registration/Amendment
http: //www. epa. sov/opprdOO 1 /forms/8570-1. pdf.
8570-4
Confidential Statement of Formula
http: //www. epa. eov/opprdOO 1 /forms/8570-4. pdf.
8570-5
Notice of Supplemental Registration of
Distribution of a Registered Pesticide
Product
http://www.epa.2ov/opprd001/forms/8570-5.pdf.
8570-1
7
Application for an Experimental Use
Permit
http: //www. epa. sov/opprdOO 1 /forms/8570-17. pdf.
8570-2
5
Application for/Notification of State
Registration of a Pesticide To Meet a
Special Local Need
http://www.epa.sov/opprd001/forms/8570-25.pdf.
8570-2
7
Formulator's Exemption Statement
http: //www. epa. sov/opprdOO 1 /forms/8570-27. pdf.
8570-2
8
Certification of Compliance with Data
Gap Procedures
http://www.epa.sov/opprd001/forms/8570-28.pdf.
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8570-3
0
Pesticide Registration Maintenance Fee
Filing
http: //www. epa. sov/opprdOO 1 /forms/8570-3 0. pdf.
8570-3
2
Certification of Attempt to Enter into
an Agreement with other Registrants for
Development of Data
http: //www. epa. sov/opprdOO 1 /forms/8570-32. pdf.
8570-3
4
Certification with Respect to Citations
of Data (in PR Notice 98-5)
http://www.epa.20v/opppmsdl/PR Notices/pr98-5.
pdf.
8570-3
5
Data Matrix (in PR Notice 98-5)
http://www.epa.gov/opppmsdl/PR Notices/pr98-5.
pdf.
8570-3
6
Summary of the Physical/Chemical
Properties (in PR Notice 98-1)
http://www.epa.sov/opppmsdl/PR Notices/pr98-l.
pdf.
8570-3
7
Self-Certification Statement for the
Physical/Chemical Properties (in PR
Notice 98-1)
http://www.epa.20v/opppmsdl/PR Notices/pr98-l.
pdf
Pesticide Registration Kit www.epa.gov/pesticides/registrationkit/.
Dear Registrant:
For your convenience, we have assembled an online registration kit which contains the following
pertinent forms and information needed to register a pesticide product with the U.S. Environmental
Protection Agency's Office of Pesticide Programs (OPP):
1. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Federal Food,
Drug and Cosmetic Act (FFDCA) as Amended by the Food Quality Protection Act (FQPA)
of 1996.
2. Pesticide Registration (PR) Notices
a. 83-3 Label Improvement Program—Storage and Disposal Statements
b. 84-1 Clarification of Label Improvement Program
c. 86-5 Standard Format for Data Submitted under FIFRA
d. 87-1 Label Improvement Program for Pesticides Applied through Irrigation Systems
(Chemigation)
e. 87-6 Inert Ingredients in Pesticide Products Policy Statement
f 90-1 Inert Ingredients in Pesticide Products; Revised Policy Statement
g. 95-2 Notifications, Non-notifications, and Minor Formulation Amendments
h. 98-1 Self Certification of Product Chemistry Data with Attachments (This
document is in PDF format and requires the Acrobat reader.)
Other PR Notices can be found at http ://www. epa. gov/opppmsd l/PR_Notices.
3. Pesticide Product Registration Application Forms (These forms are in PDF format and will
require the Acrobat reader.)
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a. EPA Form No. 8570-1, Application for Pesticide Registration/Amendment
b. EPA Form No. 8570-4, Confidential Statement of Formula
c. EPA Form No. 8570-27, Formulator's Exemption Statement
d. EPA Form No. 8570-34, Certification with Respect to Citations of Data
e. EPA Form No. 8570-35, Data Matrix
4. General Pesticide Information (Some of these forms are in PDF format and will require the
Acrobat reader.)
a. Registration Division Personnel Contact List
Biopesticides and Pollution Prevention Division (BPPD) Contacts
Antimicrobials Division Organizational Structure/Contact List
d. 53 F.R. 15952, Pesticide Registration Procedures; Pesticide Data Requirements
(PDF format)
e. 40 CFR Part 156, Labeling Requirements for Pesticides and Devices (PDF format)
f.. 40 CFR Part 158, Data Requirements for Registration (PDF format)
g.. 50 F.R. 48833, Disclosure of Reviews of Pesticide Data (November 27, 1985)
Before submitting your application for registration, you may wish to consult some additional
sources of information. These include:
1. The Office of Pesticide Programs' Web Site
2. The booklet "General Information on Applying for Registration of Pesticides in the United
States", PB92-221811, available through the National Technical Information Service (NTIS)
at the following address:
National Technical Information Service (NTIS)
5285 Port Royal Road
Springfield, VA 22161
The telephone number for NTIS is (703) 605-6000. Please note that EPA is currently in the
process of updating this booklet to reflect the changes in the registration program resulting
from the passage of the FQPA and the reorganization of the Office of Pesticide Programs.
We anticipate that this publication will become available during the Fall of 1998.
3. The National Pesticide Information Retrieval System (NPIRS) of Purdue University's Center
for Environmental and Regulatory Information Systems. This service does charge a fee for
subscriptions and custom searches. You can contact NPIRS by telephone at (765) 494-6614
or through their Web site.
4. The National Pesticide Telecommunications Network (NPTN) can provide information on
active ingredients, uses, toxicology, and chemistry of pesticides. You can contact NPTN by
telephone at (800) 858-7378 or through their Web site: ace.orst.edu/info/nptn.
The Agency will return a notice of receipt of an application for registration or amended
registration, experimental use permit, or amendment to a petition if the applicant or
259
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petitioner encloses with his submission a stamped, self-addressed postcard. The postcard
must contain the following entries to be completed by OPP:
Date of receipt
EPA identifying number
Product Manager assignment
Other identifying information may be included by the applicant to link the acknowledgment
of receipt to the specific application submitted. EPA will stamp the date of receipt and
provide the EPA identifying File Symbol or petition number for the new submission. The
identifying number should be used whenever you contact the Agency concerning an
application for registration, experimental use permit, or tolerance petition.
To assist us in ensuring that all data you have submitted for the chemical are properly coded
and assigned to your company, please include a list of all synonyms, common and trade
names, company experimental codes, and other names which identify the chemical
(including "blind" codes used when a sample was submitted for testing by commercial or
academic facilities). Please provide a CAS number if one has been assigned.
Documents Associated with this RED
The following documents are part of the Administrative Record for this RED document and
may be included in the EPA's Office of Pesticide Programs Public Docket. Copies of these documents are
not available electronically, but may be obtained by contacting the person listed on the respective Chemical
Status Sheet.
Health and Environmental Effects Science Chapters.
Detailed Label Usage Information System (LUIS) Report.
260
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