Draft Risk Evaluation for Asbestos Part 2 – Systematic Review Supplemental File: Data Quality Evaluation and Data Extraction Information for Physical and Chemical Properties CASRN: 1332-21-4


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SEPA

April 2024

United States	Office of Chemical Safety and

Environmental Protection Agency	Pollution Prevention

Draft Risk Evaluation for
Asbestos Part 2 -
Supplemental Evaluation Including Legacy Uses and
Associated Disposals of Asbestos

Systematic Review Supplemental File:

Data Quality Evaluation and Data Extraction Information for
Physical and Chemical Properties

CASRN: 1332-21-4

April 2024

-------
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April 2024

This supplemental file contains information regarding the data extraction and evaluation results for data sources that were
considered for the Supplement to the Draft Risk Evaluation for Asbestos Part 2: Supplemental Evaluation Including Legacy
Uses and Associated Disposals of Asbestos that underwent systematic review. EPA used the TSCA systematic review process
described in the Draft Systematic Review Protocol Supporting TSCA Risk Evaluations for Chemical Substances (also referred
to as the '2021 Draft Systematic Review Protocol'). The systematic review steps are further described in the Draft Risk
Evaluation for Asbestos Part 2: Supplemental Evaluation Including Legacy Uses and Associated Disposals of Asbestos -
Systematic Review Protocol. EPA conducted data extractions and data quality evaluations based on author-reported descriptions
and results; additional analyses (e.g., statistical analyses) potentially conducted by EPA are not contained in this supplemental
file. Additionally, the overall quality determination (OQD) for each reference represents the data as a whole for each study, and
not for individual metric domains within a study.

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Table of Contents

Table of Contents

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Asbestos Cement Wastes. Rocznik Ochrona Srodowiska 21(2):855-867.

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

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Virta, R. L. (2004). Asbestos. 3:288-319.

Yoshikawa, N., Kashimura, K., Hashiguchi, M., Sato, M., Horikoshi, S., Mitani, T., Shinohara, N. (2015). Detoxification mechanism of
asbestos materials by microwave treatment. Journal of Hazardous Materials 284(Elsevier):201-206.

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Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Ascorbic acid. : 117.

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NIOSH, (2014). International chemical safety cards (ICDC): Chrysotile.

NIOSH, (2014). International chemical safety cards (ICDC): Crocidolite.

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

Virta, R. L. (2004). Asbestos. 3:288-319.

Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

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Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

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Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2): 198-
215.

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Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer
studies: A pictorial presentation.

Burdett, G. J., Rood, A. P. (1983). Membrane-filter, direct-transfer technique for the analysis of asbestos fibers or other inorganic particles
by transmission electron microscopy. Environmental Science and Technology 17(ll):643-648.

Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function
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Duncan, K. E., Cook, P. M., Gavett, S. H., Dailey, L. A., Mahoney, R. K., Ghio, A. J., Roggli, V. L., Devlin, R. B. (2014). In vitro
determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Particle
and Fibre Toxicology 11(2):2.

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Gentry, J. W. (1987). SURVEY OF RECENT MEASUREMENTS WITH ASBESTOS FIBERS. Journal of Aerosol Science 18(5):47-486.

Huntington, J. C., Ptasienski, J. J., Bunker, K. L., Strohmeier, B. R., Van Orden, D. R., Lee, R. J. (2008). A new method for fracturing
mineral particles for cross-sectional FESEM analysis. Periodico di Mineralogia 77(2):43-50.

Keane, M. J., Stephens, J. W., Zhong, B. Z., Miller, W. E., Ong, T. M., Wallace, W. E. (1999). A study of the effect of chrysotile fiber
surface composition on genotoxicity in vitro. Journal of Toxicology and Environmental Health, Part A: Current Issues 57(8):529-541.

Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

Lebaron, E. I., Boettner, E. A. (1980). Fiber motion analysis by two-pulse holography. Applied Optics 19(6):891-894.

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Patitsas, A. J. (1988). SIZE CHARACTERIZATION OF ASBESTOS FIBERS USING THE RAYLEIGH-DEBYE-GANS THEORY.
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Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). Size-selective preparation of inorganic fibers for biological experiments. American
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Timbrell, V. (1982). Deposition and retention of fibres in the human lung. Annals of Occupational Hygiene 26(l-4):347-369.

Timbrell, V., Grittiths, D. M., Pooley, F. D. (1971). Possible Biological Importance of Fibre Diameters of South African Amphiboles.
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U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information
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USGS, (2009). Particle size characterization of water-elutriated libby amphibole 2000 and RTI international amosite.

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

Van Orden, D. R., Lee, R. J., Badger, S. (2006). Characterizing asbestos fiber comminution resulting from preparation of environmental
samples. Powder Technology 162(3): 183-189.

Virta, R. L„ Segreti, J. M. (1987). A MODEL FOR PREDICTING CROCIDOLITE FIBER SIZE DISTRIBUTIONS. Environmental
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Virta, R. L., Shedd, K. B., Wylie, A. G., Snyder, J. G. (1983). Chapter 47. Size and shape characteristics of amphibole asbestos (amosite)
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Wagner, J. (2015). Analysis of serpentine polymorphs in investigations of natural occurrences of asbestos. Environmental Science: Pro-
cesses & Impacts 17(5):985-996.

Webber, J. S., Blake, D. J., Ward, T. J., Pfau, J. C. (2008). Separation and characterization of respirable amphibole fibers from Libby,
Montana. Inhalation Toxicology 20(8):733-740.

Wu, L., Ortiz, C. P., Jerolmack, D. J. (2017). Aggregation of Elongated Colloids in Water. Langmuir 33(2):622-629.

ACToR, (2021). ACToR: Asbestos.

Cameo Chemicals, (2016). Chemical datasheet: asbestos.

Cameo Chemicals, (2016). Chemical datasheet: asbestos (blue).

(2017). PubChem: Crocidolite.

NIOSH, (2007). NIOSH pocket guide to chemical hazards.

NIOSH, (2016). NIOSH pocket guide to chemical hazards: Asbestos.

NIOSH, (2019). NIOSH pocket guide to chemical hazards: Asbestos.

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
(2017). PubChem: Chrysotile.

(2017). PubChem: Crocidolite.

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Table of Contents

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-
160.

Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer
studies: A pictorial presentation.

Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

Elsevier, (2021). Reaxys: physical-chemical property data for Richterite.

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update.
Microchemical Journal 72(3):251-254.

Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical
Journal 39(2): 145-148.

(2017). PubChem: Chrysotile.

NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

Seshan, K. (1983). How are the physical and chemical properties of chrysotile asbestos altered by a 10-year residence in water and up to 5
days in simulated stomach acid?. Environmental Health Perspectives 53(NOV):143-148.

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information
System (IRIS).

Verkouteren, J. R., Wylie, A. G., Steel, E. B., Lim, M. S. (1995). Analysis of the tremolite/actinolite series using high precision refractive
index measurements. Microbeam Analysis :27-28.

Virta, R. L. (2004). Asbestos. 3:288-319.

Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of
textile. Integrated Ferroelectrics 188(1): 136-147.

Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2): 198-
215.

Keane, M. J., Stephens, J. W., Zhong, B. Z., Miller, W. E., Ong, T. M., Wallace, W. E. (1999). A study of the effect of chrysotile fiber
surface composition on genotoxicity in vitro. Journal of Toxicology and Environmental Health, Part A: Current Issues 57(8):529-541.

Lavkulich, L. M., Schreier, H. E., Wilson, J. E. (2014). Effects of natural acids on surface properties of asbestos minerals and kaolinite.
Journal of Environmental Science and Health, Part A: Toxic/Hazardous Substances & Environmental Engineering 49(6):617-624.

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Table of Contents

Light, W. G., Wei, E. T. (1977). Surface charge and hemolytic activity of asbestos. Environmental Research 13(1):135-145.

Light, W. G., Wei, E. T. (1977). Surface charge and asbestos toxicity. Nature 265(5594):537-539.

NIH, (2016). Report on carcinogens: Asbestos.

Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal
of Hazardous Materials 276:469-479.

Schiller, J. E., Payne, S. L. (1980). Surface charge measurements of amphibole cleavage fragments and fibres.

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

Vidovic, K., Lovrecek, B., Hraste, M. (1996). Influence of surface charge on sedimentation and filtration behaviour of fibrous material.
Chemical and Biochemical Engineering Quarterly 10(l):33-38.

Wu, L., Ortiz, C. P., Jerolmack, D. J. (2017). Aggregation of Elongated Colloids in Water. Langmuir 33(2):622-629.

Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

Elsevier, (2021). Reaxys: physical-chemical property data for Tremolite.

Addison, W. E., Neal, G. H., Sharp, J. H., White, A. D. (1966). Amphiboles. Part IV. Surface properties of amosite and crocidolite. Journal
of the Chemical Society. Section A: Inorganic, Physical, and Theoretical Chemistry 1966:79-81.

Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-
160.

Bartosiewicz, L. (1973). Improved Techniques of Identification and Determination of Airborne Asbestos. American Industrial Hygiene
Association Journal 34(6):252-259.

Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite,
actinolite, and anthophyllite).

Lahondere, D., Cagnard, F., Wille, G., Duron, J., Misseri, M. (2018). TEM and FESEM characterization of asbestiform and non-asbestiform
actinolite fibers in hydrothermally altered dolerites (France). Environmental Earth Sciences 77(10):385.

(2017). PubChem: Chrysotile.

Seshan, K. (1983). How are the physical and chemical properties of chrysotile asbestos altered by a 10-year residence in water and up to 5
days in simulated stomach acid?. Environmental Health Perspectives 53(NOV):143-148.

Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Envi-
ronmental Research 23(2):348-361.

Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other
elongated mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association Journal 48(5):471-477.

Thorne, P. S., Lightfoot, E. N., Albrecht, R. M. (1985). Physicochemical characterization of cryogenically ground, size separated, fibro-
genic particles. Environmental Research 36(1):89-110.

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information
System (IRIS).

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6873950

Vaillancourt, A., Denes, G., Le Van Mao, R. (1997). Reactivity of chrysotile asbestos in acids: Mechanism of transformation to silicon
dioxide hemihydrate upon leaching of magnesium. Materials Research Society Symposium Proceedings, vol. 453 :71-76.

3827175
3859385
6880237

Miscellaneous

3646977	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

List of Abbreviations and Acronyms for Data Quality Evaluation and Extraction Tables

Virta, R. L. (2011). Asbestos. :l-40.

Virta, R. L. (2004). Asbestos. 3:288-319.

Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2): 198-
215.

495

497
500
516

518
521

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Asbestos

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Physical Form or State

HERO ID: 3647242 Table: 1 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; chrysotile
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

colorless to light brown upon being heated; nonpleochroic
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 11 of 522

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Asbestos

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Physical Form or State

HERO ID: 3647242 Table: 2 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; chrysotile
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

wavy fibers with kinks; splayed ends on larger bundles
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 12 of 522

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Asbestos

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Physical Form or State

HERO ID: 3647242 Table: 3 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite
None; experimental; not reported
NR; NR; NR; NR

None; NR; fibers; NR Notes: riebeckite
characteristic blue color; pleochroic
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 13 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 4 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite
None; experimental; not reported
NR; NR; NR; NR

None; NR; fibers; NR Notes: Reported as: Crocidolite (Riebeckite)

straight fibers and fiber bundles; longer fibers show curvature; splayed ends on bundles

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 14 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 5 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; anthophyllite
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

straight fibers and fiber bundles; cleavage fragments may be present.
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 15 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 6 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; anthophyllite
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

colorless to light brown; non-pleochroic to weakly pleochroic
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 16 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 7 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

14567-73-8; tremolite
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

straight and curved fibers; cleavage fragment common; large fiber bundles show splayed ends
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 17 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 8 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

14567-73-8; tremolite

None; experimental; not reported

NR; NR; NR; NR

None; NR; fibers; NR

colorless

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 18 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 9 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

13768-00-8; actinolite
None; experimental; not reported
NR; NR; NR; NR
None; NR; fibers; NR

straight and curved fibers; cleavage fragment common; large fiber bundles show splayed ends
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 19 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 10 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

13768-00-8; actinolite

None; experimental; not reported

NR; NR; NR; NR

None; NR; fibers; NR

green; weakly to moderately pleochroic

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 20 of 522

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Asbestos

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April 2024

Physical Form or State

HERO II): 3647242 Table: 11 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-73-5; cummingtonite-grunerite (amosite)

None; experimental; not reported
NR; NR; NR; NR

None; NR; fibers; NR Notes: amosite

straight fibers and fiber bundles; bundle ends appear broom-like or splayed
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 21 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3647242 Table: 12 of 12

Study Citation: Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3647242

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-73-5; cummingtonite-grunerite (amosite)

None; experimental; not reported
NR; NR; NR; NR

None; NR; fibers; NR Notes: amosite

colorless to brown upon heating; may be weakly pleochroic

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination High

Page 22 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 786664 Table: 1 of 5

Study Citation: ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Physical Form or State

Template:

HERO ID: 786664

EXTRACTION

Parameter Data

CASRN and Test Material 17068-78-9; anthophyllite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; solid; NR Notes: NR

Results Value solid

Results Details gray, white, brown-gray, green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 23 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 786664 Table: 2 of 5

Study Citation: ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Physical Form or State

Template:

HERO ID: 786664

EXTRACTION

Parameter Data

CASRN and Test Material 1200f-28-4; crocidolite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; solid; NR Notes: NR

Results Value solid

Results Details lavender, blue, green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 24 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 786664 Table: 3 of 5

Study Citation: ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Physical Form or State

Template:

HERO ID: 786664

EXTRACTION

Parameter Data

CASRN and Test Material 12f72-73-5; amosite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; solid; NR Notes: NR

Results Value solid

Results Details brown, gray, greenish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 25 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 786664 Table: 4 of 5

Study Citation: ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Physical Form or State

Template:

HERO ID: 786664

EXTRACTION

Parameter Data

CASRN and Test Material 1200f-29-5; chrysotile

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; solid; NR Notes: NR

Results Value solid

Results Details white, gray, green, yellowish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 26 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 786664 Table: 5 of 5

Study Citation: ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Physical Form or State

Template:

HERO ID: 786664

EXTRACTION

Parameter Data

CASRN and Test Material 14567-73-8; tremolite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; solid; NR Notes: NR

Results Value solid

Results Details white to pale green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 27 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 733675 Table: 1 of 3

Study Citation: Bignon, J. (1989). Mineral fibres in the non-occupational environment. IARC Scientific Publication no. 90 :3-29.

OECD Harmonized Physical Form or State

Template:

HERO ID: 733675

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; None

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: cummingtonite-grunerite

Results Value Brown asbestos

Results Details Amphibole mineral group, Mg7(0H)2Si8022 Fe7(0H)2Si8022

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 28 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 733675 Table: 2 of 3

Study Citation: Bignon, J. (1989). Mineral fibres in the non-occupational environment. IARC Scientific Publication no. 90 :3-29.

OECD Harmonized Physical Form or State

Template:

HERO ID: 733675

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; None

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: riebeckite

Results Value Blue asbestos

Results Details Amphibole mineral group, Na2Fe2 3+ Fe2+(0H)2Si8022

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 29 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 733675 Table: 3 of 3

Study Citation: Bignon, J. (1989). Mineral fibres in the non-occupational environment. IARC Scientific Publication no. 90 :3-29.

OECD Harmonized Physical Form or State

Template:

HERO ID: 733675

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; None

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: NR

Results Value White asbestos

Results Details Serpentine mineral group, (MgFe)6(OH)8Si4O10

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Physical Form or State

HERO ID: 3981007 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Cameo Chemicals, (2016). Chemical datasheet: asbestos.
Physical Form or State

3981007

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; Asbestos

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Slender, strong, flexible fibers; white, gray, green, or brown
Not Reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Physical Form or State

HERO ID: 3981008 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Cameo Chemicals, (2016). Chemical datasheet: asbestos (blue).
Physical Form or State

3981008

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; Crocidolite

None; Experimental; Not applicable

NR; NR; NR; NR

NR; NR; Not Reported; NR Notes: NR
Slender, fine, flaxy fiber; blue
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Physical Form or State

HERO ID: 3646977 Table: 1 of 4

Study Citation:	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3646977

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR Notes: white asbestos; chemical formula 3MgO 2Si02 2H20

Results Value	Typical chemical analysis of solid

Results Details	40.3% Silica (Si02), 0.7% Alumina (A1203), 1.0% Ferrous oxide (FeO), 1.5% Ferric oxide (Fe203), 0.2% Calcium oxide (CaO), 42.4% Magne-
sium oxide (MgO), 0.2% Carbon dioxide (C02), 13.7% water of crystallization

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3646977 Table: 2 of 4

Study Citation:	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3646977

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-28-4; Crocidolite

Confidentiality, Type, and Guideline	None; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR Notes: blue asbestos; chemical formula Na20 3FeO Fe203 8Si02 H20

Results Value	Typical chemical analysis of solid

Results Details	51.4% Silica (Si02), 20.3% Ferrous oxide (FeO), 17.5% Ferric oxide (Fe203), 0.1% Manganous oxide (MnO), 0.8% Calcium oxide (CaO), 1.4%

Magnesium oxide (MgO), 6.2% Sodium oxide (Na20), 0.4% Carbon dioxide (C02), 1.9% water of crystallization

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3646977 Table: 3 of 4

Study Citation:	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3646977

EXTRACTION

Parameter	Data

CASRN and Test Material	12172-73-5; Amosite

Confidentiality, Type, and Guideline	None; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR Notes: chemical formula 1.5MgO 5.5FeO 8Si02 H20

Results Value	Typical chemical analysis of solid

Results Details	49.3% Silica (Si02), 40.9% Ferrous oxide (FeO), 0.4% Ferric oxide (Fe203), 0.7% Manganous oxide (MnO), 0.4% Calcium oxide (CaO), 5.7%

Magnesium oxide (MgO), 0.2% Sodium oxide (Na20), 0.3% Potassium oxide (K20), 0.2% Carbon dioxide (C02), 1.9% water of crystallization

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3646977 Table: 4 of 4

Study Citation:	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3646977

EXTRACTION

Parameter	Data

CASRN and Test Material	77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline	None; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR Notes: chemical formula 7MgO 8Si02 H20; CAS 17068-78-9

Results Value	Typical chemical analysis of solid

Results Details	57.2% Silica (Si02), 10.1% Ferrous oxide (FeO), 0.1% Ferric oxide (Fe203), 1.0% Calcium oxide (CaO), 29.2% Magnesium oxide (MgO), 0.1%

Sodium oxide (Na20), 0.1% Potassium oxide (K20), 2.2% water of crystallization

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

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Asbestos

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Physical Form or State

HERO ID: 7607106 Table: 1 of 2

Study Citation:	Haz-Map, (2021). Haz-Map: Asbestos.

OECD Harmonized Physical Form or State

Template:

HERO ID:	7607106

EXTRACTION

Parameter	Data

CASRN and Test Material	1332-21-4; Asbestos

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	Not Reported; Not Reported; Not Reported; Not Reported

Radiolabel, Source, State, and Purity	Not Reported; Not Reported; Not Reported; Not Reported Notes: Chrysotile; Amosite; Crocidolite; Anthophylite; Tremolite; Actinolite; CAS

Numbers: 1332-21-4; 12001-28-4; 12172-73-5; 77536-66-4; 77536-67-5; 77536-68-6; 132207-32-0

Results Value	solid

Results Details	Chrysotile is a curly fiber in intertwined bundles; Amphiboles are straight and needle-like in shape

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Medium
High

Data are reported for the subject chemical substance; however multiple CAS for various
forms are reported.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cites: 'Sullivan p. 1215'

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Asbestos

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Physical Form or State

HERO ID: 7607106 Table: 2 of 2

Study Citation:	Haz-Map, (2021). Haz-Map: Asbestos.

OECD Harmonized Physical Form or State

Template:

HERO ID:	7607106

EXTRACTION

Parameter	Data

CASRN and Test Material	1332-21-4; Asbestos

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	Not Reported; Not Reported; Not Reported; Not Reported

Radiolabel, Source, State, and Purity	Not Reported; Not Reported; Not Reported; Not Reported Notes: Chrysotile; Amosite; Crocidolite; Anthophylite; Tremolite; Actinolite; CAS

Numbers: 1332-21-4; 12001-28-4; 12172-73-5; 77536-66-4; 77536-67-5; 77536-68-6; 132207-32-0

Results Value	solid

Results Details	White or greenish (chrysotile), blue (crocidolite), or gray-green (amosite) fibrous, odorless solids

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Medium
High

Data are reported for the subject chemical substance; however multiple CAS for various
forms are reported.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cites: NIOSH

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Asbestos

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Physical Form or State

HERO ID: 7607107 Table: 1 of 2

Study Citation: Haz-Map, (2021). Haz-Map: Anthophyllite.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7607107

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; Anthophyllite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; solid; NR Notes: NR

solid

Gray, white, brown-gray, or green solid

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data includes references to the original sources.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Value reported under HERO ID for Primary source: IARC 2012 HERO ID 3970851

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Asbestos

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Physical Form or State

HERO ID: 7607107 Table: 2 of 2

Study Citation:	Haz-Map, (2021). Haz-Map: Anthophyllite.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	7607107

Parameter

Data

EXTRACTION



CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; Anthophyllite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; solid; NR Notes: NR

solid

White or gray fibrous solid





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Low
N/A

The data are from a primary source without expert peer-review or an unknown sec-
ondary source without peer-review and references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

* Related References: Cites: SPIMSDS

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 1 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
lavender, blue green
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 2 of 12

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; chrysotile

Confidentiality, Type, and Guideline	none; not specified; None

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	None; NR; solid; NR

Results Value	Curled sheet silicate, hollow central core

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 3 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; chrysotile
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
white, grey, green, yellowish
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 4 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-73-5; amosite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
brown, grey, greenish
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 5 of 12

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

CASRN and Test Material	12172-73-5; amosite

Confidentiality, Type, and Guideline	none; not specified; none

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	None; NR; solid; NR

Results Value	double chain silicate; long, straight, coarse fibers

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Physical Form or State

HERO ID: 3970851 Table: 6 of 12

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

CASRN and Test Material	77536-67-5; anthophyllite

Confidentiality, Type, and Guideline	none; not specified; none

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	None; NR; solid; NR

Results Value	double chain silicate; short, very brittle fibers

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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Physical Form or State

HERO ID: 3970851 Table: 7 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-66-4; actinolite

none; not specified; none

NR; NR; NR; NR

None; NR; solid; NR

double chain silicate; brittle fibers

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 8 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-67-5; anthophyllite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
grey, white, brown-grey, green
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 9 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-66-4; actinolite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
green

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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Physical Form or State

HERO ID: 3970851 Table: 10 of 12

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Physical Form or State

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-68-6; tremolite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
white to pale green
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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Physical Form or State

HERO ID: 3970851 Table: 11 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-68-6; tremolite

none; not specified; none

NR; NR; NR; NR

None; NR; solid; NR

double chain silicate; brittle fibers

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3970851 Table: 12 of 12

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
double chain silicate
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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Physical Form or State

HERO ID: 3084215 Table: 1 of 1

Study Citation: Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3084215

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; chrysotile

None; Experimental; not applicable

NR; NR; NR; NR

NR; NR; Solid; NR Notes: NR

Solid

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical's physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed source.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 53 of 522

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Asbestos

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Physical Form or State

HERO ID: 3860485 Table: 1 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Physical Form or State

3860485

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile

none; not specified; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

White or greenish fibrous, odorless solid.

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: OSHA Occupational Chemical DB (not a primary source)

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Asbestos

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Physical Form or State

HERO ID: 3860485 Table: 2 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Physical Form or State

3860485

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile

none; not specified; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

White or greenish (chrysotile), blue (crocidolite), or gray-green (amosite) fibrous, odorless solids.
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: N/OSH-PocketGuide, OSHA Occupational Chemical DB (not a primary source)

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Physical Form or State

HERO ID: 3860485 Table: 3 of 5

Study Citation: (2017). PubChem: Chrysotile.

OECD Harmonized Physical Form or State
Template:

HERO ID: 3860485

EXTRACTION

Parameter

Data

CASRN and Test Material

12001-29-5; Chrysotile

Confidentiality, Type, and Guideline

none; not specified; Not Reported

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; NR; NR Notes: NR

Results Value

Curled sheet silicate, spiraled as helix around central capillary; fibrous member of serpentine mineral group possessing rolled trioctahedral clay

structure.

Results Details

Not Reported

EVALUATION

Domain

Metric Rating Comments

Domain 1: Substance

Metric 1:

Representativeness High Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness High Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity) towards a particular product or outcome.

Metric 4: Reliability/Analytical Method N/A Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Source: IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization,International Agency for
Research on Cancer, 1972-PRESENT. (Multivolume work). Available at:http://monographs.iarc.fr/ENG/Classiflcation/index.php , p. V14 12 (1977) (notaprimary source)

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Physical Form or State

HERO ID: 3860485 Table: 4 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Physical Form or State

3860485

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile

none; not specified; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

White, grey, green or yellowish fibrous solid.

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: ILO-ICSC (not a primary source)

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Asbestos

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Physical Form or State

HERO ID: 3860485 Table: 5 of 5

Study Citation: (2017). PubChem: Chrysotile.

OECD Harmonized Physical Form or State
Template:

HERO ID: 3860485

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline none; not specified; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: NR

Results Value Crystal system: monoclinic (pseudoorthorhombic); usually white to grayish green; may have tan coloration.

Results Details Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Source: Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V3 (1992) 671 (not a
primary source)

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Physical Form or State

HERO ID: 3860486 Table: 1 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Physical Form or State

3860486

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite

none; experimental; not reported

NR; NR; NR; NR

NR; NR; solid; NR Notes: NA

solid

lavender, blue or greenish, fibrous solid

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing ILO-ICSC.

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Asbestos

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Physical Form or State

HERO ID: 3860486 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Physical Form or State

3860486

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite

none; experimental; not reported

NR; NR; NR; NR

NR; NR; solid; NR Notes: NA

solid

blue fibrous, odorless solid

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing OSHA Occupational Chemical DB.

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Asbestos

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Physical Form or State

HERO ID: 3860489 Table: 1 of 1

Study Citation:	(2016). Agent name: Anthophyllite.

OECD Harmonized	Physical Form or State
Template:

HERO ID:	3860489

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; Anthophyllite
None; experimental; Not reported
NR; NR; NR; NR
NR; NR; Solid; NR Notes: NR

Gray, white, brown-gray, or green solid; White or gray fibrous solid
Fibrous mineral

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: IARC and SPI MSDS

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 1 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3982328

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; actinolite

none; not specified; not specified

NR; NR; NR; NR

NR; Not Reported; solid; NR Notes: common contaminant in amosite deposits
brittle fibers
pale to dark green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 2 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3982328

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; Not Reported; solid; NR Notes: common contaminant in chrysotile and talc deposits
brittle fibers
white to gray

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 3 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3982328

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; solid; NR

solid fibers, long, straight, coarse, somewhat flexible
ash gray, greenish, or brown



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1973, 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 4 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3982328

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; occurs naturally; solid; NR Notes: composition: Mg3Si205(0H)4

solid; curled sheet silicate, which wraps around itself forming hollow tubular fibers

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1973, 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 5 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3982328

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; anthophyllite
none; not specified; not specified
NR; NR; NR; NR

NR; Not Reported; solid; NR Notes: occasionally occurs as a contaminant in talc deposits
solid fibers, short, very brittle
grayish white, brown-gray, or green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1973, 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 3982328 Table: 6 of 6

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3982328

EXTRACTION

Parameter	Data

CASRN and Test Material	1332-21-4; crocidolite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; solid; NR

Results Value	shorter, thinner fibers compared to other amphiboles; not as thin as chrysotile

Results Details	lavender or blue; good flexibility and fair spinnability

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1973, 1977, IPCS 1986

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Asbestos

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Physical Form or State

HERO ID: 192177 Table: 1 of 1

Study Citation:	NIOSH, (2007). NIOSH pocket guide to chemical hazards.

OECD Harmonized Physical Form or State

Template:

HERO ID:	192177

EXTRACTION

Parameter	Data

CASRN and Test Material	1332-21-4; Asbestos

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR Notes: NR

Results Value	White or greenish (chrysotile), blue (crocidolite), or gray-green (amosite); fibrous, odorless solids

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:	Databases	Medium The data are from a source that is known but is missing elements required for High

designation such as peer-review, public availability, or the inclusion of references to
original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos

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Physical Form or State

HERO ID: 3974865 Table: 1 of 1

Study Citation: NIOSH, (2016). NIOSH pocket guide to chemical hazards: Asbestos.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3974865

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-4; Asbestos
None; Experimental; None
NR; NR; NR; NR
NR; NR; NR; NR Notes: NR

Fibrous, odorless solids. White or greenish (chrysotile), blue (crocidolite), or gray-green (amosite).
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: None cited.

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Asbestos

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Physical Form or State

HERO ID: 3978149 Table: 1 of 1

Study Citation:	NIOSH, (2014). International chemical safety cards (ICDC): Chrysotile.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	3978149

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR Notes: NR

White, grey, green or yellowish fibrous solid

None



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 70 of 522

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Asbestos

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Physical Form or State

HERO ID: 3978150 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIOSH, (2014). International chemical safety cards (ICDC): Crocidolite.
Physical Form or State

3978150

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; Crocidolite

None; Experimental; None

NR; NR; NR; NR

NR; NR; NR; NR Notes: riebeckite

Reported as Fibres

Blue asbestos





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical's physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 71 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 9109830 Table: 1 of 1

Study Citation: NIOSH, (2019). NIOSH pocket guide to chemical hazards: Asbestos.

OECD Harmonized Physical Form or State

Template:

HERO ID: 9109830

EXTRACTION

Parameter

Data

CASRN and Test Material

1332-21-4; Asbestos

Confidentiality, Type, and Guideline

none; not specified; not specified

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; NR; NR Notes: Hydrated mineral silicates

Results Value

solid

Results Details

White or greenish (chrysotile), blue (crocidolite), or gray-green (amosite) fibrous, odorless solids.

EVALUATION

Domain

Metric Rating Comments

Domain 1: Substance

Metric 1:

Representativeness High Data are for the subject chemical substance.

Metric 2:

Appropriateness High Data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity) towards a particular product or outcome.

Metric 4: Reliability/Analytical Method N/A Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Primary reference not reported in this secondary source.

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827272 Table: 1 of 6

Study Citation:	U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID:	3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-8; Libby amphibole
none; Experimental; not specified
NR; NR; NR; NR
NR; NR; NR; NR Notes: NR
Surface area (m2/g): 1.1-7.4

Elongated mineral particle surface area by transmission electron microscopy (m2/g): 1.1-2.6; Total surface area by gas adsorption (m2/g): 5.3-7.4

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with subject chemical structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained using accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The data are from a publicly available secondary source with reference to the original
sources.

The metric is not applicable to the study type.

Overall Quality Determination	High

* Related References: Duncan, KE; Cook, PM; Gavett, SH; Dailey, LA; Mahoney, RK; Ohio, AJ; Roggli, VL; Devlin, RB. (2014). In vitro determinants of asbestos fiber toxicity: effect on
the relative toxicity of Libby amphibole in primary human airway epithelial cells. Part Fibre Toxicol 11. http://dx.doi.org/10.1186/1743-8977-ll-2

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April 2024

Physical Form or State

HERO ID: 3827272 Table: 2 of 6

Study Citation:	U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID:	3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

1332-21-8; Libby amphibole
none; Experimental; not specified
NR; NR; NR; NR
NR; NR; NR; NR Notes: NR

Essential composition: Winchite (84%), richterite (11%), and tremolite (6%).

Mineral composition of individual fiber structures was determined using EDS and electron probe microanalysis.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.
The metric is not applicable to the study type.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained using accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The data are from a publicly available secondary source with reference to the original
sources.

The metric is not applicable to the study type.

Overall Quality Determination	High

* Related References: Meeker, GP; Bern, AM; Brownfield, IK; Lowers, HA; Sutley, SI; Hoefen, TM; Vance, IS. (2003). The composition and morphology of amphiboles from the Rainy
Creek Complex, near Libby, Montana. Am Mineral 88: 1955-1969.

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827272 Table: 3 of 6

Study Citation: U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-66-4; actinolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Straight to curved fibers and bundles.

Colorless to pale green.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827272 Table: 4 of 6

Study Citation: U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

77536-68-6; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Straight to curved fibers and bundles.

Colorless to pale green.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 76 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827272 Table: 5 of 6

Study Citation: U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-76-7; richterite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Straight to curved fibers and bundles.

Colorless, pale yellow, brown, pale to dark green, or violet.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Deer and Zussman (1997) Rock Forming Minerals Volume 2B: Double Chain Silicates, 2nd Edition. The Geological Society, London. HERO ID 2079162

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Asbestos

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Physical Form or State

HERO ID: 3827272 Table: 6 of 6

Study Citation: U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Physical Form or State
Template:

HERO ID: 3827272

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12425-92-2; winchite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Straight to curved fibers and bundles.

Colorless to pale blue.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Physical Form or State

HERO ID: 3975020 Table: 1 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; NR

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Value	Color: usually white to grayish green; may have tan coloration

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation given.

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Asbestos

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Physical Form or State

HERO ID: 3975020 Table: 2 of 4

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3975020

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; Crocidolite

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Color: Cobalt blue to lavender blue

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation given.

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Asbestos

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Physical Form or State

HERO ID: 3975020 Table: 3 of 4

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3975020

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-73-5; Amosite

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Color: Yellowish gray to dark brown

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation given.

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3975020 Table: 4 of 4

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3975020

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

14567-73-8; Tremolite

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Color: Gray-white, green, yellow, blue

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation given.

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Asbestos

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Physical Form or State

HERO ID: 3859385 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Physical Form or State

3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

vitreous to pearly luster; coarse but somewhat pliable texture
yellowish gray to dark brown

Domain

Metric

EVALUATION

Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

N/A Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3859385 Table: 2 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Physical Form or State

3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

silky to dull luster; soft to harsh texture

cobalt blue to lavender blue

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 84 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3859385 Table: 3 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Physical Form or State

3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

silky luster; generally harsh texture

gray-white, green, yellow, blue

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 85 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3859385 Table: 4 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Physical Form or State

3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

silky luster; silky, soft to harsh texture

white to grayish green; may have tan coloration

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Physical Form or State

HERO ID: 6860096 Table: 1 of 1

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Physical Form or State
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

CASRN and Test Material 1332-21-4; Asbestos

Confidentiality, Type, and Guideline None; not specified; NA

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NR; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample

Results Value Fiber

Results Details Edge color of fiber white, amaranth/orange/yellow, purple, blue/blue-green, white

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Physical Form or State

HERO ID: 7924810 Table: 1 of 2

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	7924810

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

5 values in Reaxys - crystal phase: Fibers (3), needles (1) Octahedrons (1)
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Thermochimica Acta 1984; Gmelin Handbuch der Anorganischen Chemie vol. Cr: MVol.Al, 3.5.3; Fortschritte der Mineralogie 1934; Ipatieff et al. Bulletin de la
Societe Chimique de France 1927; Journal of Alloys and Compounds 2008

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Asbestos

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April 2024

Physical Form or State

HERO ID: 7924810 Table: 2 of 2

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized Physical Form or State

Template:

HERO ID:	7924810

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

NR; NR; NR; NR
NR; NR; Solid; NR

3 values reported in Reaxys - Crystal system: monoclinic, rhombic, and hexagonal
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Gmelin Handbuch der Anorganischen Chemie; vol, Mg: MVol.Al; 2,8, page 102 -110; Wang, Xun; Zhuang, Jing; Chen, Jun; Zhou, Kebin; Li, Yadong; Angewandte
Chemie - International Edition;vol. 43; nb, 15; (2004); p. 2017 - 2020

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Asbestos

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Physical Form or State

HERO ID: 7924812 Table: 1 of 2

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Anthophyllite.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924812

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

17068-78-9; Anthophyllite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

2 values reported in Reaxys - Crystal phase: needles, prisms
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Walitzi, E. M.; Walter, F.; Ettinger, K.; Zeitschrift fur Kristallographie; ; vol. 188; (1989); p. 237 - 244

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Asbestos

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April 2024

Physical Form or State

HERO ID: 7924812 Table: 2 of 2

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Anthophyllite.

OECD Harmonized Physical Form or State

Template:

HERO ID:	7924812

EXTRACTION

Parameter	Data

CASRN and Test Material	17068-78-9; Anthophyllite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

NR; NR; NR; NR
NR; NR; Solid; NR

1 value reported in Reaxys - Crystal system: rhombic
Not Reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Gmelin Handbuch der Anorganischen Chemie; vol, Al: MVol.Al; 23, page 65 - 67Warren, B, E.; Modell, D, I,, Zeitschrift fur Kristallographie und Mineralogie,
1930, vol, 75, p. 161 - 161

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Physical Form or State

HERO ID: 7924814 Table: 1 of 2

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Tremolite.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924814

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

14567-73-8; Tremolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

1 values reported in Reaxys - Crystal phase: fibers. Collected using the search term 'tremolite' in Reaxys.
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Bhattacherjee, S.; Paul, A.; Journal of Materials Science; ; vol. 27; (1992); p. 704 - 710

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Physical Form or State

HERO ID: 7924814 Table: 2 of 2

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Tremolite.

OECD Harmonized Physical Form or State

Template:

HERO ID:	7924814

EXTRACTION

Parameter	Data

CASRN and Test Material	14567-73-8; Tremolite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

NR; NR; NR; NR
NR; NR; Solid; NR

1 values reported in Reaxys - Crystal system: Monoclinic. Collected using the search term 'tremolite' in Reaxys.
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Bhattacherjee, S.; Paul, A.; Journal of Materials Science; ; vol. 27; (1992); p. 704 - 710

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Physical Form or State

HERO ID: 7924815 Table: 1 of 1

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Actinolite.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924815

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12172-67-7; Actinolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

1 value reported in Reaxys - Crystal system: monoclinic
Collected using the search term 'actinolite' in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Gmelin Handbuch der Anorganischen Chemie; vol. Al: MVol.Al; 23, page 65 - 67

Page 94 of 522

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Physical Form or State

HERO ID: 7924733 Table: 1 of 2

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

Chrystal system: monoclinic (pseudoorthorhombic)
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 2 of 2

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details

12001-29-5; Chrysotile
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; Solid; NR

Curled sheet silicate, helix spiralled around a capillary. Fibrous with trioctahedral clay structure.
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on
Cancer, 1972-PRESENT. (Multivolume work), p. V14: 12 (1977)

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 1 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: weak, undergoes fairly rapid attack; Resistance to bases: very good; wt. % loss after 2 hr reflux with 25% acid or base:

55.69% (HC1), 23.42% (CH3COOH), 55.18% (H3P04), 55.75% (H2S04), 0.99% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25%
acid or base: 56.00% (HC1), 24.02% (CH3COOH), 56.45% (H3P04), 56.00% (H2S04), 1.03% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 97 of 522

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 2 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: fair to good

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 98 of 522

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 3 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: good

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 99 of 522

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 4 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-28-4; Crocidolite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: fair; Resistance to bases: good; wt. % loss after 2 hr reflux with 25% acid or base: 4.38% (HC1), 0.91% (CH3COOH), 4.37%

(H3P04), 3.69% (H2S04), 1.35% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25% acid or base: 3.14% (HC1), 1.02% (CH3COOH),
3.91% (H3P04), 3.48% (H2S04), 1.20% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 100 of 522

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 5 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	12172-73-5; Amosite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: fair, slowly attacked; Resistance to bases: good; wt. % loss after 2 hr reflux with 25% acid or base: 12.84% (HC1), 2.63%

(CH3COOH), 11.67% (H3P04), 11.35% (H2S04), 6.97% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25% acid or base: 12.00% (HC1),
3.08% (CH3COOH), 11.83% (H3P04), 11.71% (H2S04), 6.82% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 101 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 6 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: generally harsh, sometimes soft

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 102 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 7 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: Gray-white, greenish, yellowish, blueish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 103 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 8 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: Grayish white, brown-gray or green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 104 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 9 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-66-4; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: Greenish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 105 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 10 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: harsh

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 106 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 11 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-66-4; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: harsh

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 107 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 12 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: generally poor, some are spinnable

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 108 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 13 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: poor

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 109 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 14 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-66-4; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: poor

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 110 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 15 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: generally brittle, sometimes flexible

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 111 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 16 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: very brittle, non-flexible

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 112 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 17 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-66-4; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: brittle and non-flexible

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 113 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 18 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	77536-68-6; Tremolite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: fair; Resistance to bases: good; wt. % loss after 2 hr reflux with 25% acid or base: 4.77% (HC1), 1.99% (CH3COOH), 4.99%

(H3P04), 4.58% (H2S04), 1.80% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25% acid or base: 4.22% (HC1), 1.41% (CH3COOH),
4.89% (H3P04), 4.74% (H2S04), 1.65% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 114 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 19 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: fair; Resistance to bases: very good; wt. % loss after 2 hr reflux with 25% acid or base: 2.66% (HC1), 0.60% (CH3COOH),

3.16% (H3P04), 2.73% (H2S04), 1.22% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25% acid or base: 2.13% (HC1), 1.04%
(CH3COOH), 3.29% (H3P04), 2.90% (H2S04), 1.77% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 115 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 20 of 30

Study Citation:	Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID:	3827307

EXTRACTION

Parameter	Data

CASRN and Test Material	77536-66-4; Actinolite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR

Results Details	Resistance to acids: fair; Resistance to bases: fair; wt. % loss after 2 hr reflux with 25% acid or base: 20.31% (HC1), 12.28% (CH3COOH),

20.19% (H3P04), 20.38% (H2S04), 9.25% (NaOH); wt. % loss after 528 hr 26 deg C exposure to 25% acid or base: 22.55% (HC1), 12.14%
(CH3COOH), 20.10% (H3P04), 20.60% (H2S04), 9.43% (NaOH)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 116 of 522

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Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 21 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: White, gray, green, yellowish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 117 of 522

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Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 22 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: Ash gray, greenish, or brown

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 118 of 522

-------
Asbestos

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April 2024

Physical Form or State

HERO ID: 3827307 Table: 23 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Color: Lavender, blue, greenish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 119 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 24 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: silky, soft to harsh

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 120 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 25 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: coarse, but somewhat pliable

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 121 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 26 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Texture: soft to harsh

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 122 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 27 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: fair

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 123 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 28 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: very good

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 124 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Physical Form or State

HERO ID: 3827307 Table: 29 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: fair

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Physical Form or State

HERO ID: 3827307 Table: 30 of 30

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Physical Form or State

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Flexibility: high

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Physical Form or State

HERO ID: 7924810 Table: 1 of 1

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized	Physical Form or State

Template:

HERO ID:	7924810





EXTRACTION

Parameter

Data





CASRN and Test Material

12001-29-5; Chrysotile





Confidentiality, Type, and Guideline

None; Experimental; Not reported





Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR





Radiolabel, Source, State, and Purity

NR; NR; Solid; NR





Results Details

6 values were reported in Reaxys -

Color: Green (1), white (3), yellowish green (1), yellowish white (1).





EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance







Metric 1:

Representativeness

High

Data are measured for the subject chemical substance.

Metric 2:

Appropriateness

N/A

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability







Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased



(Method Objectivity)



towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

N/A

Rating of this factor is not applicable to this kind of information.

Domain 3: Other







Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are







peer-reviewed by experts in the field, are broadly available to the public for review and







use OR includes references to the original sources.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Devecerski et al.; Journal of Alloys and Compounds; vol. 464; nb. 1-2; (2008); p. 270 - 276; Zhu et al.; Inorganic Chemistry; vol. 51; nb. 11; (2012); p. 6020 -
6031; Hall, A. L.; South Africa geol. Surv. Mem. Nr. 12 {1930} 28

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Physical Form or State

HERO ID: 7924812 Table: 1 of 1

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Anthophyllite.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924812

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

17068-78-9; Anthophyllite
None; Experimental; Not reported
NR; NR; NR; NR
NR; NR; Solid; NR

3 values reported in Reaxys - Color: Light brown, pale green, and white.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Gmelin Handbuch der Anorganischen Chemie; vol. Al: MVol.Al; 23, page 65 - 67; Walitzi, E. M.; Walter, F.; Ettinger, K.; Zeitschrift fur Kristallographie; ; vol.
188; (1989); p. 237 - 244

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Asbestos

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Physical Form or State

HERO ID: 5333260 Table: 1 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

1332-21-4; Asbestos
None; Experimental; Not reported
NR; NR; NR; NR
NR; NR; NR; NR

Color: White, gray, green, or brown.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HEROID: 8001410

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Physical Form or State

HERO ID: 5333260 Table: 2 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material 1332-21-4; Asbestos

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Spinnability: Possible with longer fibers (serpentine asbestos); brittle and cannot be spun (amphibole asbestos)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: HEROID: 8001410

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Physical Form or State

HERO ID: 5333260 Table: 3 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material 1332-21-4; Asbestos

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Details Composition: magnesium silicate (serpentine); magnesium, iron, calcium, and sodium silicates (amphibole)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: HEROID: 8001410

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Physical Form or State

HERO ID: 5333260 Table: 4 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

77536-67-5; Anthophyllite
None; Experimental; Not reported
NR; NR; NR; NR
NR; NR; Solid; NR

Composition: magnesium and iron silicates.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HEROID: 8001216

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Physical Form or State

HERO ID: 5333260 Table: 5 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Mohs hardness: 5 to 6

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: HEROID: 8001314

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Physical Form or State

HERO ID: 5333260 Table: 6 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

77536-68-6; Tremolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Color: white to light-green

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HEROID: 8001314

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Physical Form or State

HERO ID: 5333260 Table: 7 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

77536-68-6; Tremolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Luster: vitreous to silky

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HEROID: 8001314

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Physical Form or State

HERO ID: 5333260 Table: 8 of 8

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Physical Form or State

Template:

HERO ID: 5333260

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

77536-66-4; Actinolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Color: greenish

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HEROID: 8001001

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Physical Form or State

HERO ID: 7924733 Table: 1 of 11

Study Citation:
OECD Harmonized
Template:

HERO ID:

NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.
Physical Form or State

7924733

EXTRACTION

Parameter

Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Color: usually white to grayish green, may have tan coloring

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Physical Form or State

HERO ID: 7924733 Table: 2 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Unit fiber average diameter: 0.025 |jm. Fiber aggregate diameters: 0.1 - 100 um. Length: fraction of a millimeter - several centimeters, but most

< 1 cm

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 3 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Composition: Silica sheet (Si205), with a layer of brucite (Mg(OH)2) with every 3 hydroxyls replaced by oxygens.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. V3: 269 (1978)

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Physical Form or State

HERO ID: 7924733 Table: 4 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Individual fiber diameter: 0.02 - 0.03 nm

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. V3: 269 (1978)

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Physical Form or State

HERO ID: 7924733 Table: 5 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Average fiber outer diameter: 200 A

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 150

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 6 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Luster: silky

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 7 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Hardness (Mohs): 2.5 - 4.0

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 8 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Optical properties: biaxial positive parallel extinction

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 9 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Flexibility: high

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 7924733 Table: 10 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Texture: silky, soft to harsh

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO II): 7924733 Table: 11 of 11

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Physical Form or State

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Tensile strength: 1100-4400 Mpa

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

The methodology is unknown, but method bias appears unlikely.
Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Physical Form or State

HERO ID: 3581598 Table: 1 of 1

Study Citation: Sucik, G., Szaboova, A., Popovic, L., Hrsak, D. (2016). The relationship between thermal treatment of serpentine and its reactivity. Materiali in Tehnologije

50(l):55-58.

OECD Harmonized Physical Form or State
Template:

HERO ID: 3581598

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details

12001-29-5; Chrysotile
None; Experimental; Not reported
NR; NR; NR; NR
NR; NR; NR; NR

Surface area: 16.2 mA2/g at 600°C to 45.2 mA2/g at 700°C and back down to 2 mA2/g at 1100°C calcination temperature.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.

Data measured for a structural analogue of the subject chemical substance are consistent
with what is expected for the subject chemical substance structural properties, features
or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Analytic method is non-standard but is expected to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

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Asbestos

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Melting Point

HERO ID: 786664 Table: 1 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Melting Point

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Melting Point	600 - 900 °C

CASRN and Test Material	12172-73-5; amosite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

NR; NR; NR; NR Notes: NR
not specified
not specified
not specified





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos

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Melting Point

HERO ID: 786664 Table: 2 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Melting Point

786664

Parameter

EXTRACTION

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

800 - 850 °C

1200f-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not specified

not specified

not specified

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Melting Point

HERO ID: 786664 Table: 3 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Melting Point

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Melting Point	800 - °C

CASRN and Test Material	12001-28-4; crocidolite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	not specified

Standard Deviation Results	not specified

Results Details	not specified

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased	Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity)	towards a particular product or outcome.

Metric 4:	Reliability/Analytical Method	Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 151 of 522

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Asbestos

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Melting Point

HERO ID: 786664 Table: 4 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Melting Point

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Melting Point	1040 - °C

CASRN and Test Material	14567-73-8; tremolite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	not specified

Standard Deviation Results	not specified

Results Details	not specified

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased	Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity)	towards a particular product or outcome.

Metric 4:	Reliability/Analytical Method	Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 152 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 786664 Table: 5 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Melting Point

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Melting Point	950 - °C

CASRN and Test Material	17068-78-9; anthophyllite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	not specified

Standard Deviation Results	not specified

Results Details	not specified

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased	Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity)	towards a particular product or outcome.

Metric 4:	Reliability/Analytical Method	Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 153 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 5155632 Table: 1 of 1

Study Citation:	California Office of Environmental Health Hazard Assessment (OEHHA) (2011). Appendix B: Chemical-specific summaries of the information used to

derive unit risk and cancer potency values.

OECD Harmonized Melting Point
Template:

HERO ID:	5155632

EXTRACTION

Parameter	Data

Melting Point	600 °C

CASRN and Test Material	1332-21-4; Asbestos

Confidentiality, Type, and Guideline	none; not specified; NR

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: decomposes at 600°C

Results Details Methods	NR

Standard Deviation Results	NR

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Citing National Institute for Occupational Safety and Health (NIOSH) 1994, HERO ID 2328101.

Page 154 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 3981007 Table: 1 of 1

Study Citation:	Cameo Chemicals, (2016). Chemical datasheet: asbestos.

OECD Harmonized Melting Point

Template:

HERO ID:	3981007

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1112 F

1332-21-4; Asbestos

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

NR

NR

Decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) or other physical/chemical properties or
behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: NIOSH, 2016 cited but no other details available

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Asbestos

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April 2024

Melting Point

HERO ID: 3981008 Table: 1 of 1

Study Citation:	Cameo Chemicals, (2016). Chemical datasheet: asbestos (blue).

OECD Harmonized Melting Point

Template:

HERO ID:	3981008

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1112 - F

12001-28-4; Crocidolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not reported

Not reported

Decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) or other physical/chemical properties or
behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: NIOSH, 2016 cited but no other details available

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Asbestos Melting Point HERO ID: 3582618 Table: 1 of 1

Study Citation: Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function of time and

temperature. American Mineralogist 92(10): 1704-1713.

OECD Harmonized Melting Point
Template:

HERO ID: 3582618

EXTRACTION

Parameter Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Results Details Methods
Standard Deviation Results
Results Details

Not Reported
12001-29-5; Chrysotile
None; Experimental; NR
NR; NR; NR; NR

NA; Thetford, Quebec, Canada; Jeffrey Mine, Asbestos, Quebec, Canada; New Idria, California; Jeffrey Mine, Asbestos, Quebec, Canada; Solid;
NR; 96%; 96%; NR Notes: 4 different samples used.

Performed in Lindberg box-type quench furnace.

Not Reported

Destruction of chrysotile began at 400°C after 4 hours, with recrystallization observed between 450 and 550°C. Complete destruction was observed
at 600°C after 4 hours or at 500°C for 30 days. Complete destruction was not observed after heating to 475°C for 30 days. Above 800°C, destruction
occurs within minutes.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Melting Point

HERO ID: 3981018 Table: 1 of 1

Study Citation:	EC, (2012). Practical guidelines for the information and training of workers involved with asbestos removal or maintenance work.

OECD Harmonized Melting Point

Template:

HERO ID:	3981018

EXTRACTION

Parameter	Data

Melting Point	> 1200 - °C

CASRN and Test Material	1332-21-4; asbestos

Confidentiality, Type, and Guideline	None; experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	NR

Standard Deviation Results	NR

Results Details	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical's physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

Data is from a publicly available secondary source.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

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Melting Point

HERO ID: 9109807 Table: 1 of 3

Study Citation: ECHA, (2021). ECHA scientific report for evaluation of limit values for asbestos at the workplace.

OECD Harmonized Melting Point

Template:

HERO ID: 9109807

EXTRACTION

Parameter Data

Melting Point 800 - 850 °C

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; NR

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; Not Reported; NR; NR Notes: white asbestos

Results Details Methods NR

Standard Deviation Results NR

Results Details NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Adapted from IARC 2012 (HERO ID 3970851) and DECOS 2010. Asbestos: Risks of environmental and occupational exposure., The Hague: Health Council of the
Netherlands; publication no. 2010/10E (Not in HERO at time of extraction).

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Melting Point

HERO ID: 9109807 Table: 2 of 3

Study Citation: ECHA, (2021). ECHA scientific report for evaluation of limit values for asbestos at the workplace.

OECD Harmonized Melting Point

Template:

HERO ID: 9109807

EXTRACTION

Parameter Data

Melting Point 600 - 900 °C

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; NR

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; Not Reported; NR; NR Notes: brown asbestos

Results Details Methods NR

Standard Deviation Results NR

Results Details NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Melting Point

HERO ID: 9109807 Table: 3 of 3

Study Citation: ECHA, (2021). ECHA scientific report for evaluation of limit values for asbestos at the workplace.

OECD Harmonized Melting Point

Template:

HERO ID: 9109807

EXTRACTION

Parameter Data

Melting Point 800 - °C

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; NR

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; Not Reported; NR; NR Notes: blue asbestos

Results Details Methods NR

Standard Deviation Results NR

Results Details NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Melting Point

HERO ID: 7924812 Table: 1 of 1

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Anthophyllite.

OECD Harmonized Melting Point

Template:

HERO ID:	7924812

EXTRACTION

Parameter	Data

Melting Point	1150- 1340 °C

CASRN and Test Material	17068-78-9; Anthophyllite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; Solid; NR

Results Details Methods	Not Reported

Standard Deviation Results	Not Reported

Results Details	1 range reported in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Sources cited: Brun, A.; Archives des Sciences Physiques et Naturelles; vol. 13; (1902); p. 363, View in Reaxys; Doelter, C.;Tschermaks Mineralogische und
Petrographische Mitteilungen; vol. 22; (1903); p. 311, View in Reaxys; Doelter, C.;Handbuch der Mineralchemie. Th. Steinkopf, Dresden-Leipzig. 1911 Bd.2, Tl.l, S.348,354, View in
Reaxys; GmelinHandbuch der Anorganischen Chemie; vol. Fe: MVol.B5; 1.8.4, page 1066 - 1069 ; (from Gmelin), View in Reaxys

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Melting Point

HERO ID: 7924815 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Actinolite.
Melting Point

7924815

Parameter

EXTRACTION

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1140- 1296 °C

12172-67-7; Actinolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Not Reported

1 range reported in Reaxys. Collected using the search term 'actinolite' in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Cusack, R.; ; vol. 4; (1897); p. 399

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Melting Point

HERO ID: 7924816 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Richterite.
Melting Point

7924816

EXTRACTION

Parameter

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1065 °C

17068-76-7; Richterite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

With decomposition. 1 value reported in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Izvestiya Akademii Nauk SSSR, Neorganicheskie Materialy; vol. 22; (1986); p. 1500 - 1505

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Melting Point

HERO ID: 3581958 Table: 1 of 1

Study Citation:	Fujishige, M., Sato, R., Kuribara, A., Karasawa, I., Kojima, A. (2006). CaC12 addition effect and melt formation in low-temperature decomposition of

chrysotile with CaC03. Ceramic Society of Japan. Journal 114(1334):844-848.

OECD Harmonized Melting Point
Template:

HERO ID:	3581958

EXTRACTION

Parameter	Data

Melting Point	> 700 - 1000 °C

CASRN and Test Material	12001-29-5; Chyrsotile

Confidentiality, Type, and Guideline	None; experimental; None

Solvent, Reactivity, Storage, and Stability	NR; Yes; NR; decomposition to forsterite and amorphous Si02 at 800°C

Radiolabel, Source, State, and Purity	NR; Kanto Chemical Co., Inc.; Solid; Reported as 1st grade Notes: 1:6 mixtures of chrysotile (Mg6Si4O10(OH)8) and CaC03 burned at temper-

atures of 500 to 1000°C

At 700°C and 800°C for 2 hours decomposition to forsterite was observed; at 1000°C larnite was identified; decomposition, to sintered products
without the formation of melts, observed at 700°C when trace CaC12 was present; material heated at temperatures for 2 hours
not reported

Decomposition temperature decreases when asbestos test substance was mixed with CaC03; addition of CaC12 further lowers decomposition
temperature.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Results Details Methods

Standard Deviation Results
Results Details

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Melting Point

HERO ID: 7473172 Table: 1 of 1

Study Citation: Goncharov, Y. I., Kholodova, N. A., Sergeev, N. E. (1991). Amphibole-based thermal-insulating ceramics. 47(7-8):267-270.

OECD Harmonized Melting Point

Template:

HERO ID: 7473172

EXTRACTION

Parameter Data

Melting Point > 600 - °C

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; experimental; High temperature heating and analysis by an x-ray diffraction method

Solvent, Reactivity, Storage, and Stability NA; yes; NR; decomposition

Radiolabel, Source, State, and Purity NR; NR; Solid; NR Notes: heated with other components as part of ceramic material investigation

Results Details Methods formation of Na-richterite at 800 deg C

Standard Deviation Results NR

Results Details Na-richterite formed by firing process at 500-1150 deg C range with magnesium oxide, quartz sand, sodium fluoride

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Medium
N/A

Data are measured or estimated for the subject chemical substance as part of a mixture.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Melting Point

HERO ID: 3970851 Table: 1 of 4

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Melting Point
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

600 - 900 °C
12127-73-5; amosite
None; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
decomposition temperature
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Melting Point

HERO ID: 3970851 Table: 2 of 4

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Melting Point
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

600 - 850 °C
12001-29-5; chrysotile
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
decomposition temperature
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Melting Point

HERO ID: 3970851 Table: 3 of 4

Study Citation:	IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Melting Point
Template:

HERO ID:	3970851

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

400 - 900 °C
12001-28-4; crocidolite
none; not specified; none
NR; NR; NR; NR
None; NR; solid; NR
decomposition temperature
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

Medium

N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Melting Point

HERO ID: 3970851 Table: 4 of 4

Study Citation: IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

OECD Harmonized Melting Point
Template:

HERO ID: 3970851

Parameter

Data

EXTRACTION

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

950- 1040°C
77536-68-6; tremolite
None; not specified; NR
NR; NR; NR; NR
None; NR; solid; NR
decomposition temperature
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Melting Point

HERO ID: 3581993 Table: 1 of 1

Study Citation: Jenkins, D. M„ Holland, T. J. B„ Clare, A. K. (1991). EXPERIMENTAL-DETERMINATION OF THE PRESSURE-TEMPERATURE STABILITY

FIELD AND THERMOCHEMICAL PROPERTIES OF SYNTHETIC TREMOLITE. American Mineralogist 76(3-4):458-469.

OECD Harmonized Melting Point
Template:

HERO ID: 3581993

EXTRACTION

Parameter Data

Melting Point = 448 - C (decomposition temperature)

CASRN and Test Material 14567-73-8; synthetic tremolite (calcic amphibole)

Confidentiality, Type, and Guideline none; experimental/calculation; non-guideline study

Solvent, Reactivity, Storage, and Stability NA; decomposition; NA; NA

Radiolabel, Source, State, and Purity NA; prepared by authors in the laboratory; solid; NR

Results Details Methods Experimental data (piston cylinder presses at 20-30 kbar, uncertainty:±200 bar; chromel-alumel thermocouples, ±5°C) and calculated univariant

curves were used to determine decomposition. Analysis of products was conducted using a Norelco X-ray diffractometer with Ni-filtered Cu
radiation.

Standard Deviation Results ±50 bars (accuracy in pressure measurements); ±2°C (accuracy of thermocouples)

Results Details Decomposition temperature at 1 bar = 448°C; decomposition to diopsidic clinopyroxene, enstatic orthopyroxene, beta-quartz, and water at pressures

of 1.5-7 bar, and decomposition to diopside and talc at temperatures of 650-760°C were reported. Upper-thermal stability at 7.5 kbar = 918°C;
upper-pressure stability at 798°C = 26.8 kbar.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Melting Point

HERO ID: 6879492 Table: 1 of 1

Study Citation:	Kusiorowski, R., Zaremba, T., Gerle, A., Piotrowski, J., Simka, W., Adamek, J. (2015). Study on the thermal decomposition of crocidolite asbestos. Journal

of Thermal Analysis and Calorimetry : 1585-1595.

OECD Harmonized Melting Point
Template:

HERO ID:	6879492

EXTRACTION

Parameter	Data

Melting Point	>= 400 - <= 920 °C

CASRN and Test Material	12001-28-4; crocidolite

Confidentiality, Type, and Guideline	none; experimental; Non-guideline; Decomposition and determination of the temperature range of the crocidolite dehydroxylation process evalu-

ated from 0-1000°C
Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; two samples examined: Republic of South Africa and crocidolite asbestos that was separated from a corrugated asbestos-cement (a-c) slate

produced from crocidolite asbestos from USSR; solid; characterized as received without any preliminary preparation Notes: Asbestos samples
were studied by differential thermal analysis (DTA) and thermogravimetry (TG/DTG). The mineralogical composition of both the natural and
heated samples (after DTA study) was evaluated by X-ray diffraction (XRD).
thermogravimetric analysis with evolved gas analysis (TG-EGA)

Not Reported

At 400°C weak endothermic effects indicate dehydroxylation, at 650-700°C weak endothermic effects indicate decomposition of impurities likely
carbonates, at 800°C strong endothermic effect for cement sample due to calcite decomposition, and at 900-920°C strong endothermic effects for
both may indicate physical melting.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Results Details Methods
Standard Deviation Results
Results Details

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Melting Point

HERO ID: 3860485 Table: 1 of 2

Study Citation:	(2017). PubChem: Chrysotile.

OECD Harmonized Melting Point

Template:

HERO ID:	3860485

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1112-F

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported

Not Reported

Decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: NIOSH-Pocket Guide (not a primary source); OSHA Occupational Chemical DB (not a primary source); CAMEO Chemicals (not a primary source)

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Melting Point

HERO ID: 3860485 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Melting Point

3860485

Parameter

EXTRACTION

Data

800 - 850 °C

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported

800-850 deg C. No melting point; decomposes.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: ATSDR; Toxicological Profile for Asbestos. Sept 2001. US Dep of Health and Human Services Agency of Toxic Substances and Disease Registry. Available
from, as of Feb 18, 2004: http://www.atsdr.cdc.gov/toxprofiles/tp61 .html (not a primary source)

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Melting Point

HERO ID: 3860486 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Melting Point

3860486

Parameter

EXTRACTION

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1112 F

12001-28-4; crocidolite

none; experimental; NR

NR; NR; NR; NR

NR; NR; solid; NR Notes: NA

NR

NR

decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing OSHA Occupational Chemical DB and CAMEO Chemicals,

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Melting Point

HERO ID: 192177 Table: 1 of 1

Study Citation:	NIOSH, (2007). NIOSH pocket guide to chemical hazards.

OECD Harmonized Melting Point

Template:

HERO ID:	192177

EXTRACTION

Parameter	Data

Melting Point	1112 - F

CASRN and Test Material	1332-21-4; chrysotile, crocidolite, or amosite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

NR; NR; NR; NR Notes: NR

NR

NR

decomposes at 1112°F





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical's physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Analytical method is unknown but is likely to be appropriate based on the data's inclu-
sion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

Data is from a recognized, peer-reviewed data collection.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Melting Point

HERO ID: 3974865 Table: 1 of 1

Study Citation:	NIOSH, (2016). NIOSH pocket guide to chemical hazards: Asbestos.

OECD Harmonized Melting Point

Template:

HERO ID:	3974865

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1112 F

1332-21-4; asbestos

Not Reported; Not Reported; Not Reported

NR; NR; NR; NR

None; NR; Solid; NR

Not Reported

Not Reported

decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

Medium

N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Melting Point

HERO ID: 3978149 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIOSH, (2014). International chemical safety cards (ICDC): Chrysotile.
Melting Point

3978149

Parameter

EXTRACTION

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1000 °C

12001-29-5; Chrysotile

None; experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported

NR

Heat resistant up to 500°C; completely decomposed at 1000°C

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Melting Point

HERO ID: 3978150 Table: 1 of 1

Study Citation:	NIOSH, (2014). International chemical safety cards (ICDC): Crocidolite.

OECD Harmonized Melting Point

Template:

HERO ID:	3978150

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

1200 °C

12001-28-4; Crocidolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: riebeckite

NR

NR

Decomposes below 1200 deg C

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Melting Point

HERO ID: 9109830 Table: 1 of 1

Study Citation:	NIOSH, (2019). NIOSH pocket guide to chemical hazards: Asbestos.

OECD Harmonized Melting Point

Template:

HERO ID:	9109830

EXTRACTION

Parameter	Data

Melting Point	= 1112 F

CASRN and Test Material	1332-21-4; Actinolite, Actinolite asbestos, Amosite (cummingtonite-grunerite), Anthophyllite, Anthophyllite asbestos, Chrysotile.Crocidolite (Riebeckite),

Tremolite, Tremolite asbestos

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: Hydrated mineral silicates

Results Details Methods	not specified

Standard Deviation Results	not specified

Results Details	decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Primary reference not reported in this secondary source.

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Melting Point

HERO ID: 7924733 Table: 1 of 1

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Melting Point

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

Melting Point 800 - 850 °C

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Details Methods Not Reported

Standard Deviation Results Not Reported

Results Details Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

The methodology is unknown, but method bias appears unlikely.

The analytic method is unknown but is expected to be appropriate based on the study's
inclusion in a peer-reviewed database.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Asbestos

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Melting Point

HERO ID: 7607109 Table: 1 of 1

Study Citation: OSHA, (2019). Asbestos, all forms.

OECD Harmonized Melting Point

Template:

HERO ID: 7607109

Parameter

Data

EXTRACTION



Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

550 (1022) - 750 (1382) C (F)

1332-21-4; Asbestos

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not reported

not reported

dehydroxylates at 550-750°C (1022-1382°F)



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Low
High

Data are measured or estimated for the subject chemical substance; specific form not

specified and data is a range corresponding to several CASRN.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

* Related References: Primary source not specified

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Asbestos

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April 2024

Melting Point

HERO ID: 6878583 Table: 1 of 1

Study Citation:	Poniatowska, A., Andrzejewska-Gorecka, D., Macherzynski, B., Kisiel, M. (2019). Thermal Decomposition of Asbestos Fiber from Asbestos Cement

Wastes. Rocznik Ochrona Srodowiska 21(2):855-867.

OECD Harmonized Melting Point
Template:

HERO ID:	6878583

EXTRACTION

Parameter	Data

Melting Point	Not Reported

CASRN and Test Material	12001-29-5; asbestos cement waste

Confidentiality, Type, and Guideline	None; Experimental; None; thermal analysis using a balance, furnace and scanning electron microscope with Energy Dispersive Spectrometry

probe and x-ray diffractometer

Solvent, Reactivity, Storage, and Stability	NA; NA; NA; NA

Radiolabel, Source, State, and Purity	NA; waste from unknown location; solid; NA Notes: NA

Results Details Methods	Thermal decomposition of cement asbestos slates occurs at 1400-1500 deg C for 120 minutes

Standard Deviation Results	NR

Results Details	At 480-520°C dehydroxylation processes of chrysotile, hydrated silicates and aluminosilicates of calcium is observed during thermal analysis; at

approximately 820°C final dehydroxylation phases of the components of cement slurry and chrysotile samples is observed; at 1250°C for 120
minutes trace amounts of chrysotile remain; at 1400°C there were no traces of chrysotile based on X-ray diffraction patterns.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance physical/chemical

properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos Melting Point HERO ID: 3975020 Table: 1 of 5

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Melting Point

Template:

HERO ID: 3975020

EXTRACTION

Parameter Data

550- 750 °C

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported

Decomposition by dehydroxylation of the brucite layer begins at 550 deg C and is completed by 750 deg C with 13% total weight loss. At 800-850
deg C the resulting magnesium silicate recrystallizes to forsterite and silica.

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.

Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Cites C. Jolicoeur and D. Duchesne, Can. J. Chem. 59(10), 1521 (1981). HEROID 6868399

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April 2024

Melting Point

HERO ID: 3975020 Table: 2 of 5

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Melting Point

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Melting Point	950 - 1040 °C

CASRN and Test Material	14567-73-8; Tremolite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	Not Reported

Standard Deviation Results	Not Reported

Results Details	Residual products: Ca, Mg, and Fe pyroxenes, silica

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.

Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation reported.

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Asbestos

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April 2024

Melting Point

HERO ID: 3975020 Table: 3 of 5

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Melting Point

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Melting Point	400 - 900 °C

CASRN and Test Material	12001-28-4; Crocidolite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	Not Reported

Standard Deviation Results	Not Reported

Results Details	Residual products: Na and Fe pyroxenes, hematite, silica

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.

Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation reported.

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Asbestos

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April 2024

Melting Point

HERO ID: 3975020 Table: 4 of 5

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Melting Point

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Melting Point	600 - 900 °C

CASRN and Test Material	12172-73-5; Amosite

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Results Details Methods	Not Reported

Standard Deviation Results	Not Reported

Results Details	Residual products: Fe and Mg pyroxenes, magnetite, hematite, silica

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.

Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citation reported.

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Asbestos

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April 2024

Melting Point

HERO ID: 3975020 Table: 5 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Melting Point

3975020

EXTRACTION

Parameter

Data

Melting Point 400 - 600 °C

CASRN and Test Material 1332-21-4; Asbestos

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: NR

Results Details Methods Not Reported

Standard Deviation Results Not Reported

Results Details Decomposition by dehydroxylation resulting to weight loss of approximately 2%. Decomposition products are pyroxenes, magnetite, hematite,

and silica.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.

Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: No citation reported.

Page 188 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 3827175 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2011). Asbestos. : 1 -40.
Melting Point

3827175

EXTRACTION

Parameter

Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

400 - 900 °C

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR

Not Reported

Not Reported

Decomposition

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Asbestos

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April 2024

Melting Point

HERO ID: 3827175 Table: 2 of 4

Study Citation:	Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized Melting Point

Template:

HERO ID:	3827175

EXTRACTION

Parameter	Data

Melting Point	600 - 850 °C

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

NR; NR; NR; NR
Not Reported
Not Reported
Decomposition





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Asbestos Melting Point HERO ID: 3827175 Table: 3 of 4

Study Citation: Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized Melting Point

Template:

HERO ID: 3827175

EXTRACTION

Parameter Data

950- 1040°C
77536-68-6; Tremolite
None; Experimental; Not Reported
NR; NR; NR; NR

NR; NR; NR; NR Notes: CAS reported in paper 14567-73-8; based on details reported in document this appear to be for the asbestiform variety
Not Reported
Not Reported
Decomposition

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Asbestos	Melting Point	HERO ID: 3827175 Table: 4 of 4

Study Citation:	Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized Melting Point

Template:

HERO ID:	3827175

EXTRACTION

Parameter	Data

Melting Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

600 - 900 °C
12172-73-5; Amosite
None; Experimental; Not Reported
NR; NR; NR; NR

NR; NR; NR; NR Notes: CAS reported in paper: Amosite [19172-73-5]
Not Reported
Not Reported
Decomposition

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





Page 192 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 3859385 Table: 1 of 4

Study Citation:	Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Melting Point

Template:

HERO ID:	3859385

EXTRACTION

Parameter	Data

Melting Point	400 - 900 °C

CASRN and Test Material	12001-28-4; crocidolite

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Details Methods
Standard Deviation Results
Results Details

NR; NR; NR; NR Notes: NR

NR

NR

Decomposition temperature = 400-900°C





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Asbestos Melting Point HERO ID: 3859385 Table: 2 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Melting Point

Template:

HERO ID: 3859385

EXTRACTION

Parameter Data

600 - 850 °C

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Decomposition temperature = 600-850°C

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Asbestos Melting Point HERO ID: 3859385 Table: 3 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Melting Point

Template:

HERO ID: 3859385

EXTRACTION

Parameter Data

600 - 900 °C

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Decomposition temperature = 600-900°C

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Asbestos Melting Point HERO ID: 3859385 Table: 4 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Melting Point

Template:

HERO ID: 3859385

EXTRACTION

Parameter Data

950- 1040°C

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Decomposition temperature = 900-1040°C

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 196 of 522

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Asbestos

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April 2024

Melting Point

HERO ID: 3531606 Table: 1 of 1

Study Citation: Yoshikawa, N., Kashimura, K., Hashiguchi, M., Sato, M., Horikoshi, S., Mitani, T., Shinohara, N. (2015). Detoxification mechanism of asbestos materials

by microwave treatment. Journal of Hazardous Materials 284(Elsevier):201-206.

OECD Harmonized Melting Point
Template:

HERO ID: 3531606

EXTRACTION

Parameter Data

Melting Point Not Reported

CASRN and Test Material not reported; Mg3Si4012 (talc) as a quasi-asbestos material was used to obtain an adequate sample for testing

Confidentiality, Type, and Guideline None; Experimental; NR

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NA; NR; Solid; NR

Results Details Methods 100 W microwave treatment

Standard Deviation Results Not Reported

Results Details Initial asbestos fibers present (49-55 present) decreased to 0 at > 900 deg C. Micro-hot spots in the CaO phase of asbestos reached > 1200 deg

C which decomposed the fibers. At > 1000 deg C, tangled fibers unraveled and expanded slightly into the interface between chrysotile fibers and
tangled fibers and CaO melted away. Thermal runaway was observed at 720 seconds.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Medium
Medium

Data are measured for a structurally similar chemical substance.

Data measured for a structural analogue of the subject chemical substance are consistent
with what is expected for the subject chemical substance structural properties, features
or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

Page 197 of 522

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Asbestos

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April 2024

Boiling Point

HERO ID: 3860485 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Boiling Point

3860485

Parameter

EXTRACTION

Data

Boiling Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Standard Deviation Results
Results Details

Not Reported

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported

Decomposes

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

N/A Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: NIOSH-Pocket Guide (not a primary source); OSHA Occupational Chemical DB (not a primary source); CAMEO Chemicals (not a primary source)

Page 198 of 522

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Asbestos

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April 2024

Boiling Point

HERO ID: 3974865 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIOSH, (2016). NIOSH pocket guide to chemical hazards: Asbestos.
Boiling Point

3974865

Parameter

EXTRACTION

Data

Boiling Point
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Standard Deviation Results
Results Details

not reported

1332-21-4; Asbestos

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported

Decomposes.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

Medium

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Metric 6:

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: None cited.

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Asbestos

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April 2024

Density

HERO ID: 786664 Table: 1 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Density

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.43 unitless

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not specified

not specified

not specified

not specified

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Density

HERO ID: 786664 Table: 2 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Density

786664

Parameter

EXTRACTION

Data

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Density Type

2.9 - 3.2 unitless

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

System

not specified



Duration

not specified



Standard Deviation Results

not specified



Results Details

not specified







EVALUATION

Domain

Metric

Rating Comments

Domain 1: Substance





Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Density

HERO ID: 786664 Table: 3 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Density

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.55 unitless

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not specified

not specified

not specified

not specified

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Density

HERO ID: 786664 Table: 4 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Density

786664

Parameter

EXTRACTION

Data

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Density Type

2.85 - 3.1 unitless
17068-78-9; anthophyllite
none; not specified; not specified
NR; NR; NR; NR
NR; NR; NR; NR Notes: NR
specific gravity

System

not specified



Duration

not specified



Standard Deviation Results

not specified



Results Details

not specified







EVALUATION

Domain

Metric

Rating Comments

Domain 1: Substance





Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Density

HERO ID: 786664 Table: 5 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Density

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.37 unitless

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not specified

not specified

not specified

not specified

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Density

HERO ID: 3646977 Table: 1 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Density

Template:

HERO ID: 3646977

EXTRACTION

Parameter Data

Density = 3.37 - unit basis not specified

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR Notes: blue asbestos; chemical formula Na20 3FeO Fe203 8Si02 H20

Density Type Specific gravity

System not specified

Duration Not reported

Standard Deviation Results Not reported

Results Details Not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Density

HERO ID: 3646977 Table: 2 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Density

Template:

HERO ID: 3646977

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

= 3.45 - unit basis not specified
12172-73-5; Amosite
none; not specified; not specified
NR; NR; NR; NR

NR; NR; Solid; NR Notes: chemical formula 1.5MgO 5.5FeO 8Si02 H20

Specific gravity

not specified

Not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Density

HERO ID: 3646977 Table: 3 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Density

Template:

HERO ID: 3646977

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

= 2.55 - unit basis not specified
12001-29-5; Chrysotile
none; not specified; not specified
NR; NR; NR; NR

NR; NR; Solid; NR Notes: white asbestos; chemical formula 3MgO 2Si02 2H20

Specific gravity

not specified

Not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Density

HERO ID: 3982121 Table: 1 of 1

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Ascorbic acid. : 117.

OECD Harmonized Density

Template:

HERO ID: 3982121

EXTRACTION

Parameter Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.5 - Not reported

1332-21-4; asbestos

None; experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

density

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

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Asbestos

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Density

HERO ID: 3860485 Table: 1 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Density

3860485

Parameter

EXTRACTION

Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.2 - 2.6 g/cm3

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

density

Not Reported

Not Reported

Not Reported

2.2-2.6 g/cm3

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: ILO-ICSC (not a primary source)

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Asbestos

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Density

HERO ID: 3860485 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Density

3860485

Parameter

EXTRACTION

Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.19 - 2.56 g/cm3

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

density

Not Reported

Chrysotile from Arizona, derived from serpentized dolimites reported to be between 2.19 & 2.25 g/mL; chrysotile from Canada approx. 2.56 g/mL.
These reported ranges in density have been attributed to mineral impurities and to the presence of magnesium silicate material that "stuffs" the
central capillaries and fibril interstices in the fiber bundle.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Density

HERO ID: 3860486 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Density

3860486

Parameter

EXTRACTION

Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.3 - 3.4 not reported

12001-28-4; crocidolite

none; experimental; not reported

NR; NR; NR; NR

NR; NR; solid; NR Notes: NR

density

not reported

NR

NR

NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing ILO-ICSC.

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Asbestos

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Density

HERO ID: 3978149 Table: 1 of 1

Study Citation:	NIOSH, (2014). International chemical safety cards (ICDC): Chrysotile.

OECD Harmonized	Density

Template:

HERO ID:	3978149

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.2 - 2.6 g/cm3

12001-29-5; Chrysotile

None; experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

density

Not reported

NR

NR

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytic method is unknown but is expected to be appropriate based on the study's
inclusion in a peer-reviewed database.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos

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Density

HERO ID: 3978150 Table: 1 of 1

Study Citation:	NIOSH, (2014). International chemical safety cards (ICDC): Crocidolite.

OECD Harmonized Density

Template:

HERO ID:	3978150

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.3 - 3.4 (water =1)

12001-28-4; Crocidolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: riebeckite

Relative density

Not reported

Not Reported

NR

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Density

HERO ID: 3975020 Table: 1 of 4

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Density

Template:

HERO ID: 3975020

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.9 - 3.2

14567-73-8; tremolite

Not Reported; Not Reported; not reported

NR; NR; NR; NR

NR; NR; NR; NR

specific gravity

Not Reported

Not Reported

Not Reported

specific gravity





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos

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April 2024

Density

HERO ID: 3975020 Table: 2 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Density

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.1 - 3.25

12172-73-5; amosite

Not Reported; Not Reported; not reported

NR; NR; NR; NR

NR; NR; NR; NR

specific gravity

Not Reported

Not Reported

Not Reported

specific gravity

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features or
other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Asbestos

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April 2024

Density

HERO ID: 3975020 Table: 3 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Density

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.2-3.3

12001-28-4; crocidolite

Not Reported; Not Reported; not reported

NR; NR; NR; NR

NR; NR; NR; NR

specific gravity

Not Reported

Not Reported

Not Reported

specific gravity

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features or
other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Asbestos

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April 2024

Density

HERO ID: 3975020 Table: 4 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Density

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.4 - 2.6

12001-29-5; chrysotile

Not Reported; Not Reported; not reported

NR; NR; NR; NR

NR; NR; NR; NR

specific gravity

Not Reported

Not Reported

Not Reported

specific gravity

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features or
other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Density

HERO ID: 3859385 Table: 1 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Density

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.9 - 3.2

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not reported

not reported

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos	Density	HERO ID: 3859385 Table: 2 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Density

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.2-3.3

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not reported

not reported

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos	Density	HERO ID: 3859385 Table: 3 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Density

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

2.4 - 2.6

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not reported

not reported

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos	Density	HERO ID: 3859385 Table: 4 of 4

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Density

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

Density

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Density Type

System

Duration

Standard Deviation Results
Results Details

3.1 - 3.25

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

specific gravity

not reported

not reported

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Asbestos

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April 2024

Density

HERO ID: 7924810 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.
Density

7924810

Parameter

EXTRACTION

Data

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

2.219 - 2.68 g/cm3

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Not Reported

Crystallographic density; 3 values were reported in Reaxys, in the range of 2.219 - 2.68.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Graham, R. P. D.; Economic Geology; vol. 12; (1917); p. 188; Dana, E. S.; A System of Mineralogy, 6.Ed., New York-London p. 671.

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Density

HERO ID: 7924812 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Anthophyllite.
Density

7924812

Parameter

EXTRACTION

Data

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

3.09 g/cm3

17068-78-9; Anthophyllite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Crystallographic density. 1 value reported in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.
The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Walitzi, E. M.; Walter, F.; Ettinger, K., Zeitschrift fur Kristallographie, 1989, vol. 188, p. 237 - 244.

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Density

HERO ID: 7924815 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Actinolite.
Density

7924815

Parameter

EXTRACTION

Data

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

2.9 - 3.1 g/cm3

12172-67-7; Actinolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Crystallographic. 1 range reported in Reaxys. Collected using the search term 'actinolite' in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Handbuch der Mineralchemie. Th. Steinkopff, Dresden-Leipzig, Vol. 2, part 1, p. 510

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Density

HERO ID: 5333260 Table: 1 of 2

Study Citation: Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.

OECD Harmonized Density

Template:

HERO ID: 5333260

Parameter

Data

EXTRACTION

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

3.0-3.3 units not given, assumed to be g/cm3

77536-68-6; Tremolite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: HEROID: 8001314

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Asbestos

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Density

HERO ID: 5333260 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Larranaga, M. D., Lewis, R. J., Lewis, R. A. (2016). Hawley's condensed chemical dictionary. :57, 58, 1232.
Density

5333260

Parameter

Data

EXTRACTION

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

2.5 units not given, assumed to be g/cm3

1332-21-4; Asbestos

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

Not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

* Related References: HEROID: 8001410

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Density

HERO ID: 7924733 Table: 1 of 2

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Density

Template:

HERO ID: 7924733

Parameter

Data

EXTRACTION

Density

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Duration

Standard Deviation Results
Results Details

2.4 - 2.6 units not given, assumed to be g/cm3

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not Reported

Specific gravity

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

The methodology is unknown, but method bias appears unlikely.
Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology.
(1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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Density

HERO ID: 7924733 Table: 2 of 2

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Density

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

Density 2.19 - 2.56 g/mL

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Duration Not Reported

Standard Deviation Results Not Reported

Results Details Arizona chystolies (derived from serpentized dolimites): 2.19 - 2.25 g/mLCanada chrystolite: 2.56 g/mLDensity ranges attibuted to mineral

impurities or presence of magnesium silicate.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

The methodology is unknown, but method bias appears unlikely.

The analytic method is unknown but is expected to be appropriate based on the study's
inclusion in a peer-reviewed database.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency forResearch on
Cancer, 1972-PRESENT. (Multivolume work), p. V14: 12 (1977)

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Density

HERO ID: 6880237 Table: 1 of 2

Study Citation: Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.

OECD Harmonized Density

Template:

HERO ID: 6880237

EXTRACTION

Parameter Data

Density 3.015 - 3.149 units not given, assumed to be g/cm3

CASRN and Test Material 12172-67-7; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Other

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Duration Not Reported

Standard Deviation Results Not reported

Results Details Specific gravity 3.015-3.149; measured using hydrostatically; 8 samples containing 65 to >98% actinolite

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Low

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a recognized, peer-reviewed data collection.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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April 2024

Density

HERO ID: 6880237 Table: 2 of 2

Study Citation: Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.

OECD Harmonized Density

Template:

HERO ID: 6880237

EXTRACTION

Parameter Data

Density 3.161 - 3.405 units not given, assumed to be g/cm3

CASRN and Test Material 12172-67-7; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Other

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Duration Not Reported

Standard Deviation Results Not reported

Results Details Specific gravity 3.161-3.405; measured hydrostatically; 4 samples containing 60-99% ferro-actinolite

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Low

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Units not reported but expected to be g/cm3.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a recognized, peer-reviewed data collection.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Particle Size

HERO ID: 3647242 Table: 1 of 6

Study Citation:	Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.

OECD Harmonized Particle Size

Template:

HERO ID:	3647242



EXTRACTION

Parameter

Data

Aerodynamic Value

Not Reported

CASRN and Test Material

12001-29-5; chrysotile

Confidentiality Type, and Guideline

None; Experimental; not reported

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

None; NR; fiber; NR

Method Type, Particle, Distribution, and Particle

Not Reported; Not Reported; Not Reported; Not Reported

Size



Geometric Standard Deviation

Not Reported

Mean

Not Reported

Standard Deviation Mean

Not Reported

Remarks

aspect ratio generally >10:1

Page Number

Not Reported

Passage

Not Reported

Mean Size Passage

Not Reported

Distribution

Not Reported

Additional Passage Details

Not Reported



EVALUATION

Domain

Metric Rating Comments

Domain 1: Substance



Metric 1:

Representativeness High Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness High Measured data are consistent with the subject chemical substance structural features or



other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased	Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity)	towards a particular product or outcome.

Metric 4:	Reliability/Analytical Method	Medium The analytical method is unknown but is likely to be appropriate based on the data's

inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:	Databases	High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review.
Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 3647242 Table: 1 of 6

... continued from previous page

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Domain

EVALUATION

Metric Rating Comments

Overall Quality Determination High



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Particle Size

HERO ID: 3647242 Table: 2 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported
12001-28-4; crocidolite
None; Experimental; not reported
NR; NR; NR; NR

None; NR; fiber; NR Notes: riebeckite

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

aspect ratio generally >10:1
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3647242 Table: 3 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported

12172-73-5; cummingtonite-grunerite
None; Experimental; not reported
NR; NR; NR; NR

None; NR; fiber; NR Notes: amosite

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

aspect ratio generally >10:1
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3647242 Table: 4 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported
17068-78-9; anthophyllite
None; Experimental; not reported
NR; NR; NR; NR
None; NR; fiber; NR

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

aspect ratio generally <10:1
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3647242 Table: 5 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported

14567-73-8; tremolite

None; Experimental; not reported

NR; NR; NR; NR

None; NR; fiber; NR

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

aspect ratio generally <10:1
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3647242 Table: 6 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Particle Size

3647242

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported

13768-00-8; actinolite

None; Experimental; not reported

NR; NR; NR; NR

None; NR; fiber; NR

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

aspect ratio generally <10:1
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 785518 Table: 1 of 2

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Particle Size
Template:

HERO ID: 785518

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

NR-NR

14567-73-8; tremolite

none; Experimental; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported; other; other; Not Reported

NR - NR NR

NR-NR

6.7% of fibers exceeded a 0.61 jUm width. Fifty-three percent of all fibers were< 1.0 jUmin length while 6% exceeded 5 jUm in length

Not Reported

NR-NR

Not Reported

NR-NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are reported for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

Continued on next page ...

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Particle Size

HERO ID: 785518 Table: 1 of 2

... continued from previous page

Study Citation:	Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Particle Size
Template:

HERO ID:	785518

Domain

Metric

EVALUATION

Rating

Comments



* Related References: Primary source not available at time of extraction: Langer, A. M., and Nolan, R. P:. Letter to the R. T. Vanderbilt Company, Inc., (March 12, 1990).

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Particle Size

HERO ID: 785518 Table: 2 of 2

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Particle Size
Template:

HERO ID: 785518

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

NR-NR

77536-68-6; winchite

none; Experimental; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported; other; other; Not Reported

NR - NR NR

NR-NR

Range of diameters: 0.1-0.2 nm, length: 1-70 nm (62%>5nm), aspect ratio: 3:1-100:1; fibers >0.45 jUmin width and >5 jUmin length, collected

on air filters, 96% had aspect ratios >10:1, 67% had 20:1 or greater aspect ratios and 10% were 50:1 or greater

Not Reported

NR-NR

Not Reported

NR-NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are reported for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5: Databases N/A Rating of this factor is not applicable to this kind of information.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Primary HERO ID 29964 - McDonald, J.C., McDonald, A. D., Armstrong, B., and Sebastien, P.: Cohort Study of Mortality ofVermiculite Miners Exposed to
Tremolite. British lournal of Industrial Medicine, 43: 436-444, (1986).

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Particle Size

HERO ID: 55 Table: 1 of 2

Study Citation:

OECD Harmonized
Template:

HERO ID:

Burdett, G. J., Rood, A. P. (1983). Membrane-filter, direct-transfer technique for the analysis of asbestos fibers or other inorganic particles by transmission
electron microscopy. Environmental Science and Technology 17(11):643-648.

Particle Size

55

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number

0.04 um - 0.06 um
12001-29-5; Chrysotile

None; Experimental; Membrane filter with TEM quantification

airborne samples collected on a membrane filter were prepared using DMF, glacial acetic acid and water; NR; NR; NR
NR; airborne samples; solid; NR Notes: NR

determination of fibre length and diameter distributions; primary particle; counted distribution; Not Reported

NR-NR
Not Reported
Not Reported

Mean fiber size = 0.04 and 0.06 um width and 1.07 and 1.17 um length from filtered suspensions of ultrasonically treated UICC chrysotile and
airborne samples from factories, respectively
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources
N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 55 Table: 1 of 2

... continued from previous page

Study Citation:	Burdett, G. J., Rood, A. P. (1983). Membrane-filter, direct-transfer technique for the analysis of asbestos fibers or other inorganic particles by transmission

electron microscopy. Environmental Science and Technology 17(11):643-648.

OECD Harmonized Particle Size
Template:

HERO ID:	55

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

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Particle Size

HERO ID: 55 Table: 2 of 2

Study Citation:	Burdett, G. J., Rood, A. P. (1983). Membrane-filter, direct-transfer technique for the analysis of asbestos fibers or other inorganic particles by transmission

electron microscopy. Environmental Science and Technology 17(11):643-648.

OECD Harmonized Particle Size
Template:

HERO ID:	55

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

0.24 um -

12172-73-5; Amosite

None; Experimental; Membrane filter with TEM quantification

airborne samples collected on a membrane filter were prepared using DMF, glacial acetic acid and water; NR; NR; NR
NR; airborne samples; solid; NR Notes: NR

determination of fibre length and diameter distributions; primary particle; counted distribution; Not Reported

NR-NR
Not Reported
Not Reported

Mean fiber size = 0.24 um width and 3.00 um length from filtered suspensions of ultrasonically treated UICC amosite

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources
N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3582618 Table: 1 of 2

Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function of time and
temperature. American Mineralogist 92(10): 1704-1713.

Particle Size

Study Citation:

OECD Harmonized
Template:

HERO ID:

3582618

EXTRACTION

Parameter

Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Average width: 0.17 |jm -
12001-29-5; Chrysotile
None; Experimental; NR
NR; NR; NR; NR

NA; Jeffrey Mine, Asbestos, Quebec, Canada; Solid; fibers and fiber bundles; 96% Chrysotile Notes: Jeffrey Plastibest 20 (CP85), referred to as
Jeffrey CP

microscopic examination; aggregate; other; Not Reported

Not Reported
Not Reported
Not Reported
Mean length: 21 nm
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.
N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 3582618 Table: 1 of 2

... continued from previous page

Study Citation:	Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function of time and

temperature. American Mineralogist 92(10): 1704-1713.

OECD Harmonized Particle Size
Template:

HERO ID:	3582618

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

* Related References: Source cited (not available at time of extraction; HERO ID 3658760 pdf missing pages): Campbell, W.J., Huggins, C.W., and Wylie, A.G. (1980) Chemical and
physical characterization of amosite, chrysotile, crocidolite, and nonfibrous tremolite for oral ingestion studies by the National Institute of Environmental HealthSciences, U.S. Bureau of
Mines Report of Investigations, RI8452, 63 p.

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Asbestos Particle Size HERO ID: 3582618 Table: 2 of 2

Study Citation: Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function of time and

temperature. American Mineralogist 92(10): 1704-1713.

OECD Harmonized Particle Size
Template:

HERO ID: 3582618

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Average width: 0.07 um -
12001-29-5; Chrysotile
None; Experimental; NR
NR; NR; NR; NR

NA; New Idria, California; Solid; fibers and fiber bundles; 96% Chrysotile
microscopic examination; aggregate; other; Not Reported

Not Reported
Not Reported
Not Reported
Mean length: 2.1 |jm
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Continued on next page ...

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Particle Size

HERO ID: 3582618 Table: 2 of 2

... continued from previous page

Study Citation:	Candela, P. A., Crummett, C. D., Earnest, D. J., Frank, M. R., Wylie, A. G. (2007). Low-pressure decomposition of chrysotile as a function of time and

temperature. American Mineralogist 92(10): 1704-1713.

OECD Harmonized Particle Size
Template:

HERO ID:	3582618





EVALUATION



Domain

Metric

Rating

Comments

* Related References: Source cited (not available at time of extraction; HERO ID 3658760 pdf missing pages): Campbell, W.J., Huggins, C.W., and Wylie, A.G. (1980) Chemical and
physical characterization of amosite, chrysotile, crocidolite, and nonfibrous tremolite for oral ingestion studies by the National Institute of Environmental Health Sciences, U.S. Bureau of
Mines Report of Investigations, RI8452, 63 p.

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Particle Size

HERO ID: 6892000 Table: 1 of 1

Study Citation:

OECD Harmonized
Template:

HERO ID:

Chatfield, E. J. (1999). Correlated measurements of airborne asbestos-containing particles and surface dust. American society for testing and materials
special technical publication 1342:378-402.

Particle Size

6892000

EXTRACTION

Parameter

Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; chrysotile

None; Experimental; Transmission electron microscope analysis of airborne dust samples from an elutriator. ISO 10312 Ambient air — Determina-
tion of asbestos fibres — Direct transfer transmission electron microscopy method and ASTM D5755-95 Standard Test Method for Microvacuum
Sampling and Indirect Analysis of Dust by Transmission Electron Microscopy for Asbestos Structure Number Concentrations
NR; NR; NR; NR

NR; Ceiling tile, floor tile, acoustic surfacing material, fireproofing, Pipe elbow cement; Solid; NR Notes: particles from chrysotile-containing
materials

microscopic examination; primary particle; other; Not Reported

Not Reported

0.5 - 34.06 µm

NR

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard; how-
ever, there is some uncertainty if the data reported is for asbestos or the dust particle.

Domain 3: Other

Continued on next page ...

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Particle Size

HERO ID: 6892000 Table: 1 of 1

... continued from previous page

Study Citation:	Chatfield, E. J. (1999). Correlated measurements of airborne asbestos-containing particles and surface dust. American society for testing and materials

special technical publication 1342:378-402.

OECD Harmonized Particle Size
Template:

HERO ID:	6892000







EVALUATION



Domain



Metric

Rating

Comments



Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.



Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 249 of 522

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Asbestos

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Particle Size

HERO ID: 3096394 Table: 1 of 1

Study Citation: Cluff, D. L., Patitsas, A. J. (1992). Size Characterization of Asbestos Fibers by Means of Electrostatic Alignment and Light-Scattering Techniques. Aerosol

Science and Technology 17(3): 186-198.

OECD Harmonized Particle Size
Template:

HERO ID: 3096394

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

0.16 (0 min centrifugation), 0.15 (5 min centrifugation), 0.12 (15 min centrifugation), and 0.11 um (20 min centrifugation) -
12001-28-4; Crocidolite
None; Experimental; NA
Light mineral oil; NR; NR; NR

NA; Union Internationale Contre le Cancer; Solid; NR Notes: Solutions sonicated for -60s and centrifuged for 0, 5, 15, or 20 min, respectively
Laser scattering/diffraction; aggregate; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next

page...

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Asbestos

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Particle Size

HERO ID: 3096394 Table: 1 of 1

... continued from previous page

Study Citation:	Cluff, D. L., Patitsas, A. J. (1992). Size Characterization of Asbestos Fibers by Means of Electrostatic Alignment and Light-Scattering Techniques. Aerosol

Science and Technology 17(3): 186-198.

OECD Harmonized Particle Size
Template:

HERO ID:	3096394

Domain

Metric

EVALUATION

Rating

Comments



Page 251 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 2342642 Table: 1 of 2

Study Citation: Duncan, K. E., Cook, P. M., Gavett, S. H., Dailey, L. A., Mahoney, R. K., Ohio, A. J., Roggli, V. L., Devlin, R. B. (2014). In vitro determinants of asbestos

fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Particle and Fibre Toxicology 11(2): 2.

OECD Harmonized Particle Size
Template:

HERO ID: 2342642

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Total particle mean width = 0.44 ± 0.01 0.43 ± 0.01 for RTI and UICC amosite, respectively -
12172-73-5; Amosite

None; Experimental; SEM and TEM analysis
NR; NR; NR; NR

NR; Research Triangle Institute (RTI) amosite and Union for International Cancer Control amosite; NR; NR Notes: NR
microscopic examination; primary particle; counted distribution; other

Not Reported
Not Reported
Not Reported

Total particle mean length = 6.4 ± 0.6 2.1 ± 0.3 and mean aspect ratio = 16.9 ± 1.6, 5.6 ± 0.6 for RTI and UICC amosite, respectively

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review.
N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next page ...
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Asbestos

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Particle Size

HERO ID: 2342642 Table: 1 of 2

... continued from previous page

Study Citation:	Duncan, K. E., Cook, P. M., Gavett, S. H., Dailey, L. A., Mahoney, R. K., Ohio, A. J., Roggli, V. L., Devlin, R. B. (2014). In vitro determinants of asbestos

fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Particle and Fibre Toxicology 11(2): 2.

OECD Harmonized Particle Size
Template:

HERO ID:	2342642

Domain

Metric

EVALUATION

Rating

Comments



Page 253 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 2342642 Table: 2 of 2

Study Citation: Duncan, K. E., Cook, P. M., Gavett, S. H., Dailey, L. A., Mahoney, R. K., Ohio, A. J., Roggli, V. L., Devlin, R. B. (2014). In vitro determinants of asbestos

fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Particle and Fibre Toxicology 11(2): 2.

OECD Harmonized Particle Size
Template:

HERO ID: 2342642

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Total particle mean width = 0.36 ± 0.02um for LA (2000) and 0.36 ± 0.01 um for LA (2007) -

1318-09-8; Libby amosite

None; Experimental; SEM and TEM analysis

NR; NR; NR; NR

NR; Libby Montana; NR; NR Notes: sampled 2000 and 2007
microscopic examination; primary particle; counted distribution; other

Not Reported
Not Reported
Not Reported

Total particle mean length =

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

3.7 and 2.3 um ± 0.2 um and mean aspect ratio = 12.8 ± 0.6, 8.4 ± 0.7for LA (2000) and LA (2007)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review.
N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 254 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3646977 Table: 1 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.
Particle Size

3646977

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; Chrysotile
none; Not specified; not specified
NR; NR; NR; NR

NR; NR; Solid; NR Notes: white asbestos; chemical formula 3MgO 2Si02 2H20
other; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Approximate diameter of smallest fibers: 0.01 micron

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

Page 255 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3646977 Table: 2 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.
Particle Size

3646977

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; Crocidolite
none; Not specified; not specified
NR; NR; NR; NR

NR; NR; Solid; NR Notes: blue asbestos; chemical formula Na20 3FeO Fe203 8Si02 H20
other; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Approximate diameter of smallest fibers: 0.08 micron

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome

The analytical method is unknown and there is no indication that a reliable method was
used

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

NEED TO FIX

Page 256 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3646977 Table: 3 of 3

Study Citation:	Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized	Particle Size

Template:

HERO ID:	3646977

Parameter

EXTRACTION

Data



Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported

12001-29-5; amosite

none; Not specified; not specified

NR; NR; NR; NR

NR; NR; Solid; NR Notes: chemical formula 1.5MgO 5.5FeO 8Si02 H20
other; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Approximate diameter of smallest fibers: 0.1 micron

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported



Domain

EVALUATION

Metric Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness High
Appropriateness Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased Medium
(Method Objectivity)

Reliability/Analytical Method Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome

The analytical method is unknown and there is no indication that a reliable method was
used

Domain 3: Other

Metric 5:
Metric 6:

Databases N/A
Models N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	NEED TO FIX

Page 257 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3580641 Table: 1 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Gentry, J. W. (1987). SURVEY OF RECENT MEASUREMENTS WITH ASBESTOS FIBERS. lournal of Aerosol Science 18(5):47-486.
Particle Size

3580641

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
1332-21-4; Asbestos

None; Experimental; Non-guideline; filtration followed by TEM analysis
aqueous suspensions; NR; NR; NR
NR; NR; Solid; NR Notes: NA

microscopic examination; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Mean diameter 0.02-0.05 nm; aspect ratio of 10-30.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Low
N/A

Data are measured or estimated for the subject chemical substance; however, many

details about the test substance are not reported.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Asbestos

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Particle Size

HERO ID: 3580641 Table: 1 of 2

... continued from previous page

Study Citation:
OECD Harmonized
Template:

HERO ID:

Gentry, J. W. (1987). SURVEY OF RECENT MEASUREMENTS WITH ASBESTOS FIBERS. lournal of Aerosol Science 18(5):47-486.
Particle Size

3580641

Domain

EVALUATION

Metric Rating Comments

Overall Quality Determination Medium



Page 259 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3580641 Table: 2 of 2

Study Citation: Gentry, J. W. (1987). SURVEY OF RECENT MEASUREMENTS WITH ASBESTOS FIBERS. lournal of Aerosol Science 18(5):47-486.

OECD Harmonized Particle Size

Template:

HERO ID: 3580641

EXTRACTION

Parameter Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
1332-21-4; Asbestos

None; Experimental; Non-guideline; Spumy Vibrating Bed Generator followed by counting using Royco 203 or Climet 208) or with a condensation

nuclei counter TSI 3020; X-ray diffraction and elemental analysis.

NR; NR; NR; NR

NR; NR; Solid; NR Notes: NA

microscopic examination; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Mean diameter 0.2-0.4 nm, aspect ratio of 5-15 (particles from vibrating beds have 1000 times the mass of samples from nebulized suspensions)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

Low Data are measured or estimated for the subject chemical substance; however, many

details about the test substance are not reported.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

Page 260 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3583340 Table: 1 of 3

Study Citation: Huntington, J. C., Ptasienski, J. J., Bunker, K. L., Strohmeier, B. R., Van Orden, D. R., Lee, R. J. (2008). A new method for fracturing mineral particles for

cross-sectional FESEM analysis. Periodico di Mineralogia 77(2):43-50.

OECD Harmonized Particle Size
Template:

HERO ID: 3583340

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported

12001-29-5; Chrysotile 1866 Standard Reference Material

None; Experimental; None

Buehler Epoxicure Resin; NR; NR; NR

NA; National Institute of Standards and Technology; Solid; NR Notes: Samples prepared by vacuum impregnation in epoxy
other; primary particle; counted distribution; Not Reported

Not Reported
Not Reported
Not Reported

Mean diameter = 0.06 um (major chord) and 0.05 um (minor chord) measured by SE FESEM

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next

page...

Page 261 of 522

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April 2024

Particle Size

HERO ID: 3583340 Table: 1 of 3

... continued from previous page

Study Citation:	Huntington, J. C., Ptasienski, J. J., Bunker, K. L., Strohmeier, B. R., Van Orden, D. R., Lee, R. J. (2008). A new method for fracturing mineral particles for

cross-sectional FESEM analysis. Periodico di Mineralogia 77(2):43-50.

OECD Harmonized Particle Size
Template:

HERO ID:	3583340

Domain

Metric

EVALUATION

Rating

Comments



Page 262 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3583340 Table: 2 of 3

Study Citation:

OECD Harmonized
Template:

HERO ID:

Huntington, J. C., Ptasienski, J. J., Bunker, K. L., Strohmeier, B. R., Van Orden, D. R., Lee, R. J. (2008). A new method for fracturing mineral particles for
cross-sectional FESEM analysis. Periodico di Mineralogia 77(2):43-50.

Particle Size

3583340

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported

12001-28-4; Chrysotile 1866 Standard Reference Material

None; Experimental; None

Buehler Epoxicure Resin; NR; NR; NR

NA; National Institute of Standards and Technology; Solid; NR Notes: Samples prepared by vacuum impregnation in epoxy
other; primary particle; counted distribution; Not Reported

Not Reported
Not Reported
Not Reported

Mean diameter = 0.09 um (major chord) and 0.07 um (minor chord) measured by SE FESEM
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 263 of 522

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April 2024

Particle Size

HERO ID: 3583340 Table: 3 of 3

Study Citation:

OECD Harmonized
Template:

HERO ID:

Particle Size

3583340

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported

12172-73-5; Chrysotile 1866 Standard Reference Material

None; Experimental; None

Buehler Epoxicure Resin; NR; NR; NR

NA; National Institute of Standards and Technology; Solid; NR Notes: Samples prepared by vacuum impregnation in epoxy
other; primary particle; counted distribution; Not Reported

Not Reported
Not Reported
Not Reported

Mean diameter = 0.23 um (major chord) and 0.15 um (minor chord) measured by SE FESEM
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 264 of 522

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Particle Size

HERO ID: 3080916 Table: 1 of 1

Study Citation: Keane, M. J., Stephens, J. W., Zhong, B. Z., Miller, W. E., Ong, T. M., Wallace, W. E. (1999). A study of the effect of chrysotile fiber surface composition

on genotoxicity in vitro. Journal of Toxicology and Environmental Health, Part A: Current Issues 57(8):529-541.

OECD Harmonized Particle Size
Template:

HERO ID: 3080916

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

not reported - not reported
12001-29-5; chrysotile asbestos

none; Not Reported; non-guideline: fiber length measurements via SEM

deionized H20 (Millipore); suspension filtered through 0.4 |jm pore size polycarbonate filter; NR; NR; NR
NR; National Institute of Environmental Health Sciences; solid; NR Notes: Intermediate-length chrysotile
microscopic examination; other; counted distribution; Not Reported

not reported - not reported not reported

ca_lower Untreated fibers: size range <3 nm count frequency: ca. 275; size range 3-10 nm count frequency: ca. 205; size range >10 |jm count
frequency: ca. 25; treated fibers: size range <3 nm count frequency: ca. 340; size range 3-10 nm count frequency: ca. 175; size range >10 nm
count frequency: ca. 15 - not reported
not reported

500 fibers measured for each sample (unmodified and acid treated); on average untreated fibers were 25% longer than treated fibers

Not Reported

not reported - not reported

Not Reported

not reported - not reported

not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 3080916 Table: 1 of 1

... continued from previous page

Study Citation:	Keane, M. J., Stephens, J. W., Zhong, B. Z., Miller, W. E., Ong, T. M., Wallace, W. E. (1999). A study of the effect of chrysotile fiber surface composition

on genotoxicity in vitro. Journal of Toxicology and Environmental Health, Part A: Current Issues 57(8):529-541.

OECD Harmonized Particle Size
Template:

HERO ID:	3080916

Domain Metric

EVALUATION

Rating

Comments

Overall Quality Determination

High





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Particle Size

HERO ID: 3084215 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.
Particle Size

3084215

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

<1.2 ,um

12172-73-5; amosite

None; Experimental; Scanning electron microscope (SEM)

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported

diameter range = <0.10 to 1.2 fim (reported in citation HERO ID 3615279)
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next page ...

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Particle Size

HERO ID: 3084215 Table: 1 of 4

... continued from previous page

Study Citation:	Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

OECD Harmonized	Particle Size

Template:

HERO ID:	3084215

Domain

Metric

EVALUATION

Rating

Comments



* Related References: HERO ID 3615279 "Physical and chemical characteristics of UICC reference samples"

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Particle Size

HERO ID: 3084215 Table: 2 of 4

Study Citation:	Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

OECD Harmonized Particle Size

Template:

HERO ID:	3084215

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

<1.0 jum

12001-28-4; crocidolite

None; Experimental; Scanning electron microscope (SEM)

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported

diameter range = <0.10 to 1.00 fim (reported in citation HERO ID 3615279)

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability







Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased



(Method Objectivity)



towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

High

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HERO ID 3615279 "Physical and chemical characteristics of UICC reference samples"

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Particle Size

HERO ID: 3084215 Table: 3 of 4

Study Citation:	Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

OECD Harmonized Particle Size

Template:

HERO ID:	3084215

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

<0.8 jum

12001-29-5; chrysotile

None; Experimental; Scanning electron microscope (SEM)

NR; NR; NR; NR

NR; NR; NR; NR Notes: Chrysotiles A and B

microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported

diameter range = <0.10 to 0.80 fim (reported in citation HERO ID 3615279)

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability







Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased



(Method Objectivity)



towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

High

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HERO ID 3615279 "Physical and chemical characteristics of UICC reference samples"

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Particle Size

HERO ID: 3084215 Table: 4 of 4

Study Citation:	Le Bouffant, L. (1980). Physics and chemistry of asbestos dust. IARC Scientific Publication No. 30 (30): 15-33.

OECD Harmonized Particle Size

Template:

HERO ID:	3084215

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

<1.4 jUm

77536-87-5; anthophyllite

None; Experimental; Scanning electron microscope (SEM)

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported

diameter range = <0.10 to 1.4 fim (reported in citation HERO ID 3615279)

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability







Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased



(Method Objectivity)



towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

High

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: HERO ID 3615279 "Physical and chemical characteristics of UICC reference samples"

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Particle Size

HERO ID: 3615886 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Lebaron, E. I., Boettner, E. A. (1980). Fiber motion analysis by two-pulse holography. Applied Optics 19(6):891-894.
Particle Size

3615886

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

ca_lower 34.0 +/-2.8 um -
12001-28-4; crocidolite

None; Experimental; Double-pulse in-line Fraunhofer holography aerosol spectrometer

NA; NR; NR; NR

NR; NR; fiber solid; NR Notes: NR

Laser scattering/diffraction; primary particle; counted distribution; Not Reported

ca_lower 12.3 +1-5 A um -
Not Reported
Not Reported

X = -0.05+/-0.34 cm, Y = 0.02+/-0.46 cm, Z = 1.09+/-0.48 cm, L = 145+/- 100 um
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 272 of 522

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Particle Size

HERO ID: 759182 Table: 1 of 2

Study Citation: Lowers, H. A., Bern, A. M. (2009). Particle size characterization of water-elutriated Libby amphibole 2000 and RTI international amosite. :3.

OECD Harmonized Particle Size

Template:

HERO ID: 759182

EXTRACTION

Parameter Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

NR-NR

1318-09-8; Libby amphibole

None; Experimental; Non-guideline: total particle characterization; scanning electron microscopy (SEM)

Water; NR; NR; NR

NR; collected by the U.S. Geological Survey in 2000; NR; NR Notes: 1083 'LA' structure indexed samples; particles with aspect ratio (length
divided by width) greater than 3 were labeled fiber, and those with aspect ratio less than three were labeled nonfiber regardless of phase identification
microscopic examination; other; other; Not Reported

NR-NR NR

NR-NR

Length (|im):
average: 7.1.

Not Reported
NR-NR
Not Reported
NR-NR
NR

range 0.21973 to 23.5979, mean 1.95; width (nm): range 0.024358 to 2.59266, mean 0.316; aspect ratio ranged from 1.0 to 128.9,
Morphologies included: stepped, single fiber, blocky, tapered, amorphous, splayed/stepped, platy, splayed, split end.

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured or estimated for the subject chemical substance.

Metric 2: Appropriateness High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next

page...

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Particle Size

HERO ID: 759182 Table: 1 of 2

... continued from previous page

Study Citation:	Lowers, H. A., Bern, A. M. (2009). Particle size characterization of water-elutriated Libby amphibole 2000 and RTI international amosite. :3.

OECD Harmonized Particle Size

Template:

HERO ID:	759182

Domain

Metric

EVALUATION

Rating

Comments



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Particle Size

HERO ID: 759182 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Lowers, H. A., Bern, A. M. (2009). Particle size characterization of water-elutriated Libby amphibole 2000 and RTI international amosite. :3.
Particle Size

759182

Parameter

EXTRACTION

Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

NR-NR

12172-73-5; Amosite

None; Experimental; Non-guideline: total particle characterization; SEM
NR; NR; NR; NR

NR; collected by RTI International; NR; NR Notes: 878 samples analyzed; particles with aspect ratio (length divided by width) greater than 3 were
labeled fiber, and those with aspect ratio less than three were labeled nonfiber regardless of phase identification
microscopic examination; other; other; Not Reported

NR-NR NR

NR-NR

NR

Length (|im): range 0.20633 to 103.582, mean 6.94; width (nm): range 0.018519 to 1.76127, mean 0.301; aspect ratio ranged from 1.0 to 360.3,

average: 24.5. Morphologies included: stepped, single fiber, blocky, tapered, matrix, curved, splayed/stepped, platy, splayed, bladed.

Not Reported

NR-NR

Not Reported

NR-NR

NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance

Measured data are consistent with the subject chemical substance structural features

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome

Data are obtained by accepted standard analytical methods

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information
Rating of this factor is not applicable to this kind of information

Overall Quality Determination

High

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Particle Size

HERO ID: 6876819 Table: 1 of 1

Study Citation: Myasoedov, A. V., Kalmykov, A. E., Kirilenko, D. A., Sorokin, L. M. (2017). TEM Investigation of Nanostructures with a High Aspect Ratio. : 143-148.

OECD Harmonized Particle Size

Template:

HERO ID: 6876819

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported

Not Reported; chrysotile

none; Experimental; high-resolution TEM

NR; NR; NR; NR

None; NR; fibers; NR

microscopic examination; other; counted distribution; Not Reported

Not Reported
nm

Not Reported

average diameter -20 nm; from figure range 6-42 nm

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features or
other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next

page...

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Particle Size

HERO ID: 6876819 Table: 1 of 1

... continued from previous page

Study Citation:	Myasoedov, A. V., Kalmykov, A. E., Kirilenko, D. A., Sorokin, L. M. (2017). TEM Investigation of Nanostructures with a High Aspect Ratio. : 143-148.

OECD Harmonized Particle Size

Template:

HERO ID:	6876819

Domain

Metric

EVALUATION

Rating

Comments



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Particle Size

HERO ID: 3982328 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIH, (2016). Report on carcinogens: Asbestos.
Particle Size

3982328

EXTRACTION

Parameter

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

NR-NR

1332-21-4; chrysotile

none; Not specified; not specified

NR; NR; NR; NR

NR; occurs naturally; solid; NR

other; other; Not Reported; Not Reported

NR-NR NR

NR-NR

NR

fiber bundles with lengths ranging from several millimeters to >10 cm

Not Reported

NR-NR

Not Reported

NR-NR

NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Continued on next page ...

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Asbestos

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Particle Size

HERO ID: 3982328 Table: 1 of 1

... continued from previous page

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIH, (2016). Report on carcinogens: Asbestos.
Particle Size

3982328





Domain

Metric

EVALUATION

Rating

Comments



* Related References: Primary source (not available in HERO at time of extraction) - Virta RL. 2002. Asbestos: Geology, Mineralogy, Mining and Uses. Open File Report 02-149. U.S.
Geological Survey, http://pubs.usgs.gov/of/2002/of02-149/of02-149.pdf.

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Particle Size

HERO ID: 3083397 Table: 1 of 1

Study Citation:	Parsons, R. C., Bryant, D. G., Edstrom, H. W. (1986). Variation in fibre and dust counts in an asbestos mine and mill. Annals of Occupational Hygiene

30(l):63-75.

OECD Harmonized Particle Size
Template:

HERO ID:	3083397

EXTRACTION

Parameter	Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

not reported - not reported
12001-29-5; chrystotile

none; Experimental; Non-guideline monitoring study: atmospheric fiber density from midget impinger and membrane filter samplers in an asbestos
mill during screening, refining, and bagging
NR; NR; NR; NR

NR; asbestos mill air samples; NR; NR Notes: NR

microscopic examination; other; counted distribution; Not Reported

not reported - not reported not reported
not reported - not reported
not reported

Highest and second highest distribution classes were the 3.0-4.2 |jm and 4.3-6.0 nm fibre length classes for both methods used (midget impinger

MI and membrane filter MF) in all three mill zones; fiber density (f/mL) >1.5 |jm: screening = 6.5 (MI) and 5.9 (MF), refining = 2.0 (MI) and 1.6

(MF), and bagging = 1.4 (MI) and 0.8 (MF); fiber density (f/mL) >5 |jm: screening = 3.5 (MI) and 2.8 (MF), refining = 1.1 (MI) and 0.8 (MF), and

bagging = 0.7 (MI) and 0.4 (MF); fiber density (f/mL) >7 nm: screening = 1.2 (MI) and 1.0 (MF), refining = 0.4 (MI) and 0.3 (MF), and bagging

= 0.2 (MI) and 0.2 (MF).

Not Reported

not reported - not reported

Not Reported

1.5 nm - 24.2 other

Frequency distribution of atmospheric fiber from MF reported at fiber levels during screening, refining, and bagging, respectively: <0.5 f/mL = 6,
25, 32; 0.5-0.6 f/mL = 0, 14, 12; 0.7-0.9 f/mL = 1, 14, 13; 1.0-1.5 f/mL = 1, 6, 3; 1.6-2.0 f/mL = 3,3,1; 2.1-5.0 f/mL = 19, 1, 2; 5.1-10.0 f/mL =
16, 0, 0; 10.1-20.0 f/mL = 14, 0, 0; 20.1-30.0 f/mL = 3, 0, 0.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is non-standard but is expected to be appropriate.

Domain 3: Other

Continued on next page ...

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Particle Size

HERO ID: 3083397 Table: 1 of 1

... continued from previous page

Study Citation:	Parsons, R. C., Bryant, D. G., Edstrom, H. W. (1986). Variation in fibre and dust counts in an asbestos mine and mill. Annals of Occupational Hygiene

30(l):63-75.

OECD Harmonized Particle Size
Template:

HERO ID:	3083397





EVALUATION

Domain

Metric

Rating

Comments

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Particle Size

HERO ID: 6872531 Table: 1 of 1

Study Citation: Patitsas, A. J. (1988). SIZE CHARACTERIZATION OF ASBESTOS FIBERS USING THE RAYLEIGH-DEBYE-GANS THEORY. lournal of Colloid

and Interface Science : 15-23.

OECD Harmonized Particle Size

Template:

HERO ID: 6872531

EXTRACTION

Parameter Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

less than 3 um (from HERO ID 3101448)

77536-67-5; anthophyllite

None; Calculation; Rayleigh-Debye-Gans approximate theory used to calculate fiber diameter and length distribution functions by fitting light
scattering data from liquid suspensions
NR; NR; NR; NR

NR; UICC sample; fiber (solid); NR Notes: UICC anthophyllite fibers
other; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported
For samples with
modal diameter =

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

no centrifugation, 2.5 and 25.0 min centrifugation the best fit geometric mean standard deviation were 0.5, 0.4 and 0.4 um and
0.238, 0.359 and 0.323 um, respectively.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

N/A Rating of this factor is not applicable to this kind of information (calculation).

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.
N/A Rating of this factor is not applicable to this kind of information.

Continued on next page .

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Particle Size

HERO ID: 6872531 Table: 1 of 1

... continued from previous page

Study Citation:	Patitsas, A. J. (1988). SIZE CHARACTERIZATION OF ASBESTOS FIBERS USING THE RAYLEIGH-DEBYE-GANS THEORY. lournal of Colloid

and Interface Science : 15-23.

OECD Harmonized Particle Size

Template:

HERO ID:	6872531

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

* Related References: Citing Timbrell V. (1972) Microscope 20, 365. HERO ID 3101448.

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Particle Size

HERO ID: 380 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Spurny, K. R. (1989). On the release of asbestos fibers from weathered and corroded asbestos cement products. Environmental Research 48(1): 100-116.
Particle Size

380

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number

0.1 um - 0.5 um
Not Reported; Asbestos

None; Experimental; Nuclepore filters samples and SEM analysis and Individual fibers were identified by energy dispersive X-ray analysis

None; NR; NR; NR

NR; Air samples; NR; NR Notes: NR

microscopic examination; primary particle; other; Not Reported
0.09-

Not Reported
Not Reported

Mean diameter = 0.22 um; mean length = 4.0 um (S.d. 2.0, range 1.7-9.5um); MEAN SIZE VALUES OF EMITTED FIBERS (GMF); total mineral
fibers (GMF)

Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Overall Quality Determination

High

Continued on next page ...

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Particle Size

HERO ID: 380 Table: 1 of 1

... continued from previous page

Study Citation:	Spurny, K. R. (1989). On the release of asbestos fibers from weathered and corroded asbestos cement products. Environmental Research 48(1): 100-116.

OECD Harmonized Particle Size

Template:

HERO ID:	380

Domain

Metric

EVALUATION

Rating

Comments



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Asbestos Particle Size HERO ID: 2073705 Table: 1 of 1

Study Citation: Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). On the evaluation of fibrous particles in remote ambient air. Science of the Total Environment

ll(l):l-40.

OECD Harmonized Particle Size
Template:

HERO ID: 2073705

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

0.01 um - 0.5 um
1332-21-4; amosite

None; Experimental; None, sampling fibrous particles in ambient air and asbestos fibers was made by electron microprobe analysis
NA; NR; NR; NR

NR; asbestos clouds and urban and non-urban ambient air; solid fiber; NR Notes: NR
microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Particle Size

HERO ID: 6867217 Table: 1 of 3

Study Citation:	Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). Size-selective preparation of inorganic fibers for biological experiments. American Industrial

Hygiene Association lournal 40(l):20-38.

OECD Harmonized Particle Size
Template:

HERO ID:	6867217

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12172-73-5; amosite

none; Experimental; Non-guideline study
NR; NR; NR; NR

NR; UICC Standard Reference; Solid fibers; NR Notes: samples were size-separated into very fine and fine fibers
microscopic examination; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Very fine fiber fraction: representative mean length 1.17 nm (±0.47), mean fiber diameter 0.23 nm (±0.07), aspect ratio = 5.40. Lengths < ljrm =

48.3%, lengths < 3|im = 99%, diameters < 0.1 |jm = 2.1%, diameters < 0.5 nm = 99%. Aspect ratios < 3 = 6.2%, aspect ratios < 30 = 100%. Fine

fiber fraction: representative mean length 2.52 |jm (±1.44), mean fiber diameter 0.47 nm (±0.17), aspect ratio = 5.29. Lengths < 3 nm = 72.1%,

lengths < 10 nm = 100%, diameters < 0.5 nm = 66.4%, diameters <1.0 |jm = 98.1%. Aspect ratios < 5 = 57.2%, aspect ratios < 50 = 100%.

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.
N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 6867217 Table: 1 of 3

... continued from previous page

Study Citation:	Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). Size-selective preparation of inorganic fibers for biological experiments. American Industrial

Hygiene Association lournal 40(l):20-38.

OECD Harmonized Particle Size
Template:

HERO ID:	6867217

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

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Particle Size

HERO ID: 6867217 Table: 2 of 3

Study Citation:

OECD Harmonized
Template:

HERO ID:

Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). Size-selective preparation of inorganic fibers for biological experiments. American Industrial
Hygiene Association lournal 40(l):20-38.

Particle Size

6867217

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; chrysotile
none; Experimental; Non-guideline study
NR; NR; NR; NR

NR; UICC Standard Reference; Solid fibers; NR Notes: samples were size-separated into very fine and fine fibers
microscopic examination; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Very fine fiber fraction: representative mean length 1.11 nm (±0.58), mean fiber diameter 0.13 nm (±0.04), aspect ratio = 8.90. Lengths < l^m =

58.1%, lengths < 3|jm = 99%, diameters < 0.1 |jm = 33.2%, diameters < 0.5 nm = 100%. Aspect ratios < 3 = 0.5%, aspect ratios < 30 = 100%.

Fine fiber fraction: representative mean length 1.42 nm (±0.83), mean fiber diameter 0.16 nm (±0.04), aspect ratio = 9.18. Lengths < 3 nm =

95.1%, lengths < 10 |jm = 100%, diameters < 0.5 |jm = 100%, diameters < 1.0 nm = NA. Aspect ratios < 5 = 17.3%, aspect ratios < 50 = 99%.

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 6867217 Table: 3 of 3

Study Citation:

OECD Harmonized
Template:

HERO ID:

Spurny, K. R., Stober, W., Opiela, H., Weiss, G. (1979). Size-selective preparation of inorganic fibers for biological experiments. American Industrial
Hygiene Association lournal 40(l):20-38.

Particle Size

6867217

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-28-4; crocidolite
none; Experimental; Non-guideline study
NR; NR; NR; NR

NR; UICC Standard Reference; Solid fibers; NR Notes: samples were size-separated into very fine and fine fibers
microscopic examination; other; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Very fine fiber fraction: representative mean length 1.35 nm (±0.83), mean fiber diameter 0.21 nm (±0.12), aspect ratio = 6.75. Lengths < l^m =

46.1%, lengths < 3|im = 97.3%, diameters < 0.1 nm = 2.1%, diameters < 0.5 |jm = 100%. Aspect ratios < 3 = 0.8%, aspect ratios < 30 = 100%.

Fine fiber fraction: representative mean length 1.39 nm (±0.89), mean fiber diameter 0.23 nm (±0.06), aspect ratio = 6.98. Lengths < 3 nm =

93.4%, lengths < 10 |jm = 100%, diameters < 0.5 nm = 99%, diameters < 1.0 jim = 100%. Aspect ratios < 5 = 46.8%, aspect ratios < 50 = 100%.

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 29927 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Timbrell, V. (1982). Deposition and retention of fibres in the human lung. Annals of Occupational Hygiene 26(1-4):347-369.
Particle Size

29927

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

0.44 and 3.8 |jm (mine), 0.52 and 4.8 nm (mill), 0.70 and 10 nm (bagging) -
17068-78-9; Anthophyllite
None; Experimental; NA
NA; NR; NR; NR

NA; Mine, mill, and bagging area dust samples in Paakkilla mine; Solid; NR

determination of fibre length and diameter distributions; aggregate; counted distribution; Not Reported

2.16 and 2.74 (mine), 1.93 and 2.42 (mill), 2.26 and 2.94 (bagging) -

Not Reported

Not Reported

Not Reported

Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Particle Size

HERO ID: 3097547 Table: 1 of 2

Study Citation: Timbrell, V., Grittiths, D. M., Pooley, F. D. (1971). Possible Biological Importance of Fibre Diameters of South African Amphiboles. Nature 232(5305):55-

56.

OECD Harmonized Particle Size
Template:

HERO ID: 3097547

EXTRACTION

Parameter Data

Aerodynamic Value North-western Cape mines: Mean fiber diameter: 0.073 nm; Mean aerodynamic diameter: 0.09 - 0.8 |jm. Transvaal mines: Mean fiber diameter:

0.212 nm; Mean aerodynamic diameter: 0.2 - 2.5 nm. -

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality Type, and Guideline None; Experimental; None

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Mines in north-western Cape and Transvaal, South Africa; Solid; NR

Method Type, Particle, Distribution, and Particle determination of fibre length and diameter distributions; other; other; Not Reported
Size

Geometric Standard Deviation

Not Reported

Mean

Not Reported

Standard Deviation Mean

Not Reported

Remarks

Not Reported

Page Number

Not Reported

Passage

Not Reported

Mean Size Passage

Not Reported

Distribution

Not Reported

Additional Passage Details

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Analytical details are missing.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

Continued on next page ...

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Particle Size

HERO ID: 3097547 Table: 1 of 2

... continued from previous page

Study Citation:	Timbrell, V., Grittiths, D. M., Pooley, F. D. (1971). Possible Biological Importance of Fibre Diameters of South African Amphiboles. Nature 232(5305):55-

56.

OECD Harmonized Particle Size
Template:

HERO ID:	3097547

Domain

Metric

EVALUATION

Rating

Comments



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Asbestos Particle Size HERO ID: 3097547 Table: 2 of 2

Study Citation: Timbrell, V., Grittiths, D. M., Pooley, F. D. (1971). Possible Biological Importance of Fibre Diameters of South African Amphiboles. Nature 232(5305):55-

56.

OECD Harmonized Particle Size
Template:

HERO ID: 3097547

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Mean fiber diameter: 0.243 nm -
12172-73-5; Amosite
None; Experimental; None
NR; NR; NR; NR

NA; Mines in Transvaal, South Africa; Solid; NR

determination of fibre length and diameter distributions; other; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Analytical details are missing.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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April 2024

Particle Size

HERO ID: 3827272 Table: 1 of 1

Study Citation:	U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Particle Size
Template:

HERO ID:	3827272

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported

1318-09-8; Libby amphibole

Not Reported; Not Reported; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

other; primary particle; counted distribution; Not Reported
Not Reported

=0.1 (width); <1 (length) - =1.0 (width); >/=100 (length) µm
not reported

cumulative particle-size-distribution frequencies of LA fibers (aspect ratio >3:1) in in Libby ore Grade 3, expanded Libby ore Grade 3, and ambient

air samples collected in Libby

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Medium The analytical method is non-standard but is expected to be appropriate OR the analyti-
cal method is unknown but is likely to be appropriate based on the data's inclusion in a
peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Continued on next page ...

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Particle Size

HERO ID: 3827272 Table: 1 of 1

... continued from previous page

Study Citation:	U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Particle Size
Template:

HERO ID:	3827272

Domain

Metric

EVALUATION

Rating Comments



Metric 6: Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High



* Related References: U.S. EPA (U.S. Environmental Protection Agency). (2010b). Particle size distribution data for Libby Amphiboles structures observed in air at the Libby Asbestos
Superfund Site [EPA Report], Denver, CO. HERO ID 759201

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April 2024

Particle Size

HERO ID: 3975014 Table: 1 of 2

Study Citation:	USGS, (2009). Particle size characterization of water-elutriated libby amphibole 2000 and RTI international amosite.

OECD Harmonized Particle Size

Template:

HERO ID:	3975014

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported

1318-09-8; Libby amphibole

none; Experimental; Non-guideline: particle characterization by SEM
NR; NR; NR; NR

NR; Field samples collected by the U.S.G.S in 2000; solid; both fiber and non-fiber; NR
microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

1081 samples analyzed via scanning electron microscopy. Fiber (particles with aspect ratio >3) sample sizes ranged from 0.347783 to 23.5979 nm
(length) and 0.24358 to 1.32475 (width) Non-Fiber (particles with aspect ratio <3) sample sizes ranged from 0.21973 to 3.09938 nm (length) and
0.0998251 to 2.59266 nm (width) Morphology of the samples included: stepped, blocky, single fiber, platy, and tapered.

EVALUATION

Domain	Metric	Rating	Comments

Domain 1: Substance

Metric 1:	Representativeness	High Data are measured or estimated for the subject chemical substance.

Metric 2:	Appropriateness	High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical method.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High







Continued on next

page...

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Particle Size

HERO ID: 3975014 Table: 1 of 2

... continued from previous page

Study Citation:	USGS, (2009). Particle size characterization of water-elutriated libby amphibole 2000 and RTI international amosite.

OECD Harmonized Particle Size

Template:

HERO ID:	3975014

Domain

Metric

EVALUATION

Rating

Comments



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Asbestos	Particle Size	HERO ID: 3975014 Table: 2 of 2

Study Citation:	USGS, (2009). Particle size characterization of water-elutriated libby amphibole 2000 and RTI international amosite.

OECD Harmonized Particle Size

Template:

HERO ID:	3975014

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12172-73-5; amosite

none; Experimental; Non-guideline: particle characterization by SEM
NR; NR; NR; NR

NR; Field samples collected by RTI International; solid; both fiber and non-fiber; NR
microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

878 samples analyzed via scanning electron microscopy. Fiber (particles with aspect ratio >3) sample sizes ranged from 0.473036 to 103.582 nm
(length) and 0.018519 to 1.33806 (width) Non-Fiber (particles with aspect ratio <3) sample sizes ranged from 0.20633 to 2.39866 |jm (length) and
0.121707 to 1.7627 |jm (width) Morphology of the samples included: single fiber, tapered, stepped, blocky, matrix, curved, platy, splayed/stepped,
bladed,splayed.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical method.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Asbestos	Particle Size	HERO ID: 3975020 Table: 1 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Particle Size

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; Chrysotile
None; Experimental; None
NR; NR; NR; NR

NR; NR; Solid, fibers; NR Notes: NR

other; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Surface area =15-30 mA2/g, measured by BET nitrogen adsorption.

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or
other physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Continued on next page ...

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Particle Size

HERO ID: 3975020 Table: 1 of 4

... continued from previous page

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Particle Size

3975020



Domain

EVALUATION

Metric Rating

Comments



* Related References: No citations reported.

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April 2024

Particle Size

HERO ID: 3975020 Table: 2 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Particle Size

3975020

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported
12001-28-4; Crocidolite
None; Experimental; None
NR; NR; NR; NR

NR; NR; Solid, fibers; NR Notes: NR

other; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Surface area =1.8-9 mA2/g
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Cites A. A. Hodgson and C. A. White, Papers 2-10, The Physics and Chemistry of Asbestos Minerals, Oxford Conference on Asbestos Minerals, Oxford, UK, 1967,
No HEROID.

Page 302 of 522

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Asbestos

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April 2024

Particle Size

HERO ID: 3975020 Table: 3 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Particle Size

3975020

Parameter

EXTRACTION

Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean

Remarks

Page Number

Not Reported
12172-73-5; Amosite
None; Experimental; None
NR; NR; NR; NR

NR; NR; Solid, fibers; NR Notes: NR

other; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Surface area = 1.3 - 5.5 mA2/g
Not Reported

Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Cites A. A. Hodgson and C. A. White, Papers 2-10, The Physics and Chemistry of Asbestos Minerals, Oxford Conference on Asbestos Minerals, Oxford, UK, 1967,
No HEROID.

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Asbestos	Particle Size	HERO ID: 3975020 Table: 4 of 4

Study Citation:	USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Particle Size

Template:

HERO ID:	3975020

EXTRACTION

Parameter	Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12001-29-5; Chrysotile
None; Experimental; None
NR; NR; NR; NR

NR; NR; Solid, fibers; NR Notes: NR

Not Reported; primary particle; Not Reported; Not Reported

Not Reported
Not Reported
Not Reported

Unit fiber diameter = 25 nm (average); Industrial fiber aggregate diameter = 0.1 to 100 um

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

EVALUATION

Domain	Metric	Rating	Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: No citations reported.

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Asbestos

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April 2024

Particle Size

HERO ID: 3584949 Table: 1 of 1

Study Citation: Van Orden, D. R., Lee, R. J., Badger, S. (2006). Characterizing asbestos fiber comminution resulting from preparation of environmental samples. Powder

Technology 162(3):183-189.

OECD Harmonized Particle Size
Template:

HERO ID: 3584949

EXTRACTION

Parameter Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

greater than or equal to 0.02 jUm - less than or equal to 0.05 jUm
12001-29-5; chrysotile

none; Experimental; Non-guideline; measurement of asbestos particle size in air samples collected in 2002-2003 inside and outside of the World
Trade Center (over 2 yrs following World Trade Center towers collapse); analysis via transmission electron microscope

NR; NR; Samples were collected on mixed cellulose ester filters and prepared in general accordance with standard direct preparation methodolo-
gies.; NR

NR; WTC air samples; single fibers; with a few bundles; NR
microscopic examination; other; mass based distribution; D99

Not Reported

greater than or equal to Length: 2 jUm (directly prepared samples) 0.43 jUm (indirectly prepared samples) - less than or equal to Length: 24.3 jUm
(directly prepared samples) 10 /im (indirectly prepared samples) µm
not reported

Asbestos fibers characterized as particles with an aspect ratio of 5:1 or greater (length/width). The minimum fiber length was restricted to 0.5 jUm

in accordance with the method used.

Not Reported

not reported - not reported

Not Reported

not reported - not reported

not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.
N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Asbestos

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April 2024

Particle Size

HERO ID: 3584949 Table: 1 of 1

... continued from previous page

Study Citation:	Van Orden, D. R., Lee, R. J., Badger, S. (2006). Characterizing asbestos fiber comminution resulting from preparation of environmental samples. Powder

Technology 162(3):183-189.

OECD Harmonized Particle Size
Template:

HERO ID:	3584949

Domain Metric

EVALUATION

Rating

Comments

Overall Quality Determination

High





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Asbestos

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April 2024

Particle Size

HERO ID: 3584086 Table: 1 of 1

Study Citation: Virta, R. L„ Segreti, J. M. (1987). A MODEL FOR PREDICTING CROCIDOLITE FIBER SIZE DISTRIBUTIONS. Environmental Research 44(1):148-

160.

OECD Harmonized Particle Size
Template:

HERO ID: 3584086

EXTRACTION

Parameter Data

Aerodynamic Value 0.02 um (width) - 0.29 um (width)

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability Filtered distilled water; NR; NR; NR

Radiolabel, Source, State, and Purity NA; NR; Solid, blocky to fibrous; NR Notes: 7 samples

Method Type, Particle, Distribution, and Particle determination of fibre length and diameter distributions; other; counted distribution; Not Reported
Size

Geometric Standard Deviation

Not Reported

Mean

Not Reported

Standard Deviation Mean

Not Reported

Remarks

Not Reported

Page Number

Not Reported

Passage

Not Reported

Mean Size Passage

Not Reported

Distribution

Not Reported

Additional Passage Details

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured or estimated for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Continued on next

page...

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Particle Size

HERO ID: 3584086 Table: 1 of 1

... continued from previous page

Study Citation:	Virta, R. L„ Segreti, J. M. (1987). A MODEL FOR PREDICTING CROCIDOLITE FIBER SIZE DISTRIBUTIONS. Environmental Research 44(1):148-

160.

OECD Harmonized Particle Size
Template:

HERO ID:	3584086

Domain

Metric

EVALUATION

Rating

Comments



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Particle Size

HERO ID: 3101498 Table: 1 of 2

Study Citation:	Virta, R. L., Shedd, K. B., Wylie, A. G., Snyder, J. G. (1983). Chapter 47. Size and shape characteristics of amphibole asbestos (amosite) and amphibole

cleavage fragments (actinolite, cummingtonite) collected on occupational air monitoring filters. :633-643.

OECD Harmonized Particle Size
Template:

HERO ID:	3101498

EXTRACTION

Parameter	Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
77536-66-4; actinolite
none; Experimental; none

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Mining samples containing actinolite were obtained from air monitoring filters from Mine Safety and Health Administration (from
stone quarry and iron mining operations in amphibole-bearing rocks).; Not Reported; Not Reported Notes: Ca2(Mg, Fe)5Si8022(0H)2
microscopic examination; other; other; Not Reported

Not Reported
Not Reported
Not Reported

Airborne Mining Sample Particle Sizes: Homestake Gold Mine: # of particle = 266; mean length (nm) = 4.6 (range 0.9 - 17.5), mean width (|jm)

= 1.1 (range 0.3 - 4.8). Peter Mitchell Iron Mine: # of particle = 464; mean length (nm) = 5.5 (range 1.0 - 32.4), mean width (|jm) = 1.2 (range 0.2

- 5.0). Charlottesville Crushed Stone: # of particle = 605; mean length (|jm) = 5.3 (range 0.8 - 36.0), mean width (|jm) = 1.4 (range 0.2 - 12.0).

Not Reported

Not Reported

Not Reported

Not Reported

Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) analysis; Most non-amphibole particles were eliminated
based on the criteria set: minimum of 250 particles with aspect ratio -2:1 for the mining site samples and -3:1 for the industrial site samples,
straight sides, and suitable amphibole composition were measured.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:	Databases	N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Asbestos

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April 2024

Particle Size

HERO ID: 3101498 Table: 1 of 2

... continued from previous page

Study Citation:	Virta, R. L., Shedd, K. B., Wylie, A. G., Snyder, J. G. (1983). Chapter 47. Size and shape characteristics of amphibole asbestos (amosite) and amphibole

cleavage fragments (actinolite, cummingtonite) collected on occupational air monitoring filters. :633-643.

OECD Harmonized Particle Size
Template:

HERO ID:	3101498

EVALUATION

Domain	Metric	Rating	Comments

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Asbestos	Particle Size	HERO ID: 3101498 Table: 2 of 2

Study Citation:	Virta, R. L., Shedd, K. B., Wylie, A. G., Snyder, J. G. (1983). Chapter 47. Size and shape characteristics of amphibole asbestos (amosite) and amphibole

cleavage fragments (actinolite, cummingtonite) collected on occupational air monitoring filters. :633-643.

OECD Harmonized Particle Size
Template:

HERO ID:	3101498

EXTRACTION

Parameter	Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

Not Reported
12172-73-5; amosite
none; Experimental; none

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Industrial samples containing amosite were obtained from Occupational Safety and Health Administration (from shipyard and
electric company industrial sites employing asbestos).; Not Reported; Not Reported Notes: (Mg,Fe)7Si8022(0H)2
microscopic examination; other; other; Not Reported

Not Reported
Not Reported
Not Reported

Airborne Industrial Sample Particle Sizes: Shipyard: # of particle = 698; mean length (|jm) = 8.2 (range 0.9 - 93.5), mean width (nm) = 0.4 (range

0.1 - 2.6). Electric Company: # of particle = 285; mean length (nm) = 15.6 (range 1.3 - 181.0), mean width (nm) = 0.5 (range 0.1 - 1.7).

Not Reported

Not Reported

Not Reported

Not Reported

Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) analysis; Most non-amphibole particles were eliminated
based on the criteria set: minimum of 250 particles with aspect ratio -2:1 for the mining site samples and -3:1 for the industrial site samples,
straight sides, and suitable amphibole composition were measured.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Asbestos

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Particle Size

HERO ID: 3101498 Table: 2 of 2

... continued from previous page

Study Citation:	Virta, R. L., Shedd, K. B., Wylie, A. G., Snyder, J. G. (1983). Chapter 47. Size and shape characteristics of amphibole asbestos (amosite) and amphibole

cleavage fragments (actinolite, cummingtonite) collected on occupational air monitoring filters. :633-643.

OECD Harmonized Particle Size
Template:

HERO ID:	3101498

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

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Asbestos

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Particle Size

HERO ID: 3531545 Table: 1 of 1

Study Citation: Wagner, J. (2015).

Analysis of serpentine polymorphs in investigations of natural occurrences of asbestos. Environmental Science: Processes & Impacts

17(5):985-996.

OECD Harmonized Particle Size

Template:

HERO ID: 3531545

EXTRACTION

Parameter

Data

Aerodynamic Value

Mean Fiber width: 42±16 nm -

CASRN and Test Material

12001-29-5; Chrysotile

Confidentiality, Type, and Guideline

None; Experimental; NA

Solvent, Reactivity, Storage, and Stability

Alcohol; NR; NR; NR

Radiolabel, Source, State, and Purity

NA; California, USA; Solid; NR Notes: Samples ground with mortar and pestle in alcohol

Method Type, Particle, Distribution, and Particle

microscopic examination; other; other; Not Reported

Size

Geometric Standard Deviation

Not Reported

Mean

Not Reported

Standard Deviation Mean

Not Reported

Remarks

Morphology - Central canal: Sharp, uniform; fiber termination: rounded/uniform; fiber side edges: parallel

Page Number

Not Reported

Passage

Not Reported

Mean Size Passage

Not Reported

Distribution

Not Reported

Additional Passage Details

Not Reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness

N/A

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

High

The methodology for producing the information is designed to answer a specific ques-

(Method Objectivity)

tion, and the methodology's objective is clear.

Metric 4:

Reliability/Analytical Method

High

Data are obtained by accepted standard analytical methods, including, but not limited to

OECD guidelines for physical-chemical properties or other developed standard. Some

study details are missing.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Asbestos

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Particle Size

HERO ID: 3531545 Table: 1 of 1

... continued from previous page

Study Citation:	Wagner, J. (2015). Analysis of serpentine polymorphs in investigations of natural occurrences of asbestos. Environmental Science: Processes & Impacts

17(5):985-996.

OECD Harmonized Particle Size
Template:

HERO ID:	3531545

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	Medium

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Particle Size

HERO ID: 711568 Table: 1 of 1

Study Citation: Webber, J. S., Blake, D. J., Ward, T. J., Pfau, J. C. (2008). Separation and characterization of respirable amphibole fibers from Libby, Montana. Inhalation

Toxicology 20(8):733-740.

OECD Harmonized Particle Size
Template:

HERO ID: 711568

EXTRACTION

Parameter Data

Aerodynamic Value
CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle
Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks

Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

less than or equal to 2.5 nm
1318-09-8; Libby amphibole

None; Experimental; transmission electron microscope and scanning transmission electron microscope with x-ray detector
sterile water; NR; NR; NR

NR; Libby 6-mix from USGS; "Libby 6-mix," includes a complex mixture of fiber sizes and nonfibrous material in addition to the respirable size
fraction; solid; NR Notes: Libby 6-mix containing six amphibole fiber types, including winchite, richterite, and tremolite; separation of Libby
6-mix into respirable and nonrespirable size fractions by means of aqueous elutriation

determination of fibre length and diameter distributions; primary particle; mass based distribution; Not Reported

Not Reported
Not Reported
Not Reported

Mean fiber dimensions of elutriated fibers were 2.7 nm (length), 0.19 nm (width), aspect ratio = 16. Surface area of elutriated fibers was 5.3 m-2

g-1, compared to 0.53 m-2 g-1 for the raw fibers and 8.1 m-2 g-1 measured for crocidolite; no detectable differences in chemical composition

between larger and smaller fibers.

Not Reported

Respirable fraction (smaller than 2.5 |jm) accounted for 13% of the raw Libby 6-mix mass); less than 2% has aerodynamic diameters greater than
2.5 |jm; 98% of elutriated fibers were at or below respirable diameters. The Libby 6-mix is a mixture of fiber sizes and nonfibrous material and
may not reflect historical samples from Libby MT.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Continued on next page ...

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Asbestos

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Particle Size

HERO ID: 711568 Table: 1 of 1

... continued from previous page

Study Citation:	Webber, J. S., Blake, D. J., Ward, T. J., Pfau, J. C. (2008). Separation and characterization of respirable amphibole fibers from Libby, Montana. Inhalation

Toxicology 20(8):733-740.

OECD Harmonized Particle Size
Template:

HERO ID:	711568

Domain



Metric

EVALUATION

Rating

Comments



Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Asbestos

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Particle Size

HERO ID: 3531568 Table: 1 of 1

Study Citation: Wu, L., Ortiz, C. P., Jerolmack, D. J. (2017). Aggregation of Elongated Colloids in Water. Langmuir 33(2):622-629.

OECD Harmonized Particle Size

Template:

HERO ID: 3531568

EXTRACTION

Parameter Data

Aerodynamic Value

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Method Type, Particle, Distribution, and Particle

Size

Geometric Standard Deviation
Mean

Standard Deviation Mean
Remarks
Page Number
Passage

Mean Size Passage
Distribution

Additional Passage Details

1.9 ± 0.5 jum -
12001-29-5; Chrysotile
None; Experimental; None
NA; NA; NA; NA

NA; El Dorado Mine, Salt River, Arizona; Solid block; > 90%
microscopic examination; primary particle; other; Not Reported

Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported
Not Reported

Length = 10 ± 0.8 fim (up to 20 fim)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Medium The analytical method is non-standard but is expected to be appropriate OR the analyti-
cal method is unknown but is likely to be appropriate based on the data's inclusion in a
peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Continued on next page ...

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Particle Size

HERO ID: 3531568 Table: 1 of 1

... continued from previous page

Study Citation:
OECD Harmonized
Template:

HERO ID:

Wu, L., Ortiz, C. P., Jerolmack, D. J. (2017). Aggregation of Elongated Colloids in Water. Langmuir 33(2):622-629.
Particle Size

3531568

Domain

Metric

EVALUATION

Rating Comments

Overall Quality Determination

High



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Asbestos

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Vapor Pressure

HERO ID: 7607028 Table: 1 of 1

Study Citation: ACToR, (2021). ACToR: Asbestos.

OECD Harmonized Vapor Pressure

Template:

HERO ID: 7607028

EXTRACTION

Parameter Data

Vapor Pressure ca. 0.00E+00 - mm Hg

CASRN and Test Material 1332-21-4; asbestos

Confidentiality, Type, and Guideline none; approximation; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR Notes: NR

Temperature
System

Standard Deviation Results
Results Details

not reported
not reported
not reported
approximate value

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Reported data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Source cited: HERO ID 594566 and HERO ID 9109830 (secondary source which does not cite primary source). NIOSH Pocket Guide to Chemical Hazards (NPG),
NIOSH Publication No. 97-140, February2004.

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Asbestos	Vapor Pressure	HERO ID: 3981007 Table: 1 of 1

Study Citation: Cameo Chemicals, (2016). Chemical datasheet: asbestos.

OECD Harmonized Vapor Pressure

Template:

HERO ID: 3981007

Parameter

Data

EXTRACTION

Vapor Pressure

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details

ca. 0 mm Hg

1332-21-4; Asbestos

None; experimental; Not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not reported

Not reported

Not reported

Reported as approximate value





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features

physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Analytical method is unknown but is likely to be appropriate based on the data's inclu-
sion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: NIOSH, 2016 cited but no other details available

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Asbestos	Vapor Pressure	HERO ID: 3981008 Table: 1 of 1

Study Citation: Cameo Chemicals, (2016). Chemical datasheet: asbestos (blue).

OECD Harmonized Vapor Pressure

Template:

HERO ID: 3981008

Parameter

Data

EXTRACTION

Vapor Pressure

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details

ca. 0 - mm Hg

12001-28-4; crocidolite

None; experimental; Not reported

NR; NR; NR; NR

NR; NR; fiber; NR Notes: NR

not reported

not reported

not reported

Reported as approximate value





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features

physical/chemical properties or behaviors.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Analytical method is unknown but is likely to be appropriate based on the data's inclu-
sion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: NIOSH, 2016 cited but no other details available

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Vapor Pressure

HERO ID: 3860486 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Vapor Pressure

3860486

EXTRACTION

Parameter

Data

Vapor Pressure

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details

ca. 0 mm Hg

12001-28-4; Crocidolite

None; experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing OSHA Occupational Chemical DB and CAMEO Chemicals.

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Asbestos

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April 2024

Vapor Pressure

HERO ID: 192177 Table: 1 of 1

Study Citation:	NIOSH, (2007). NIOSH pocket guide to chemical hazards.

OECD Harmonized Vapor Pressure

Template:

HERO ID:	192177

EXTRACTION

Parameter	Data

Vapor Pressure	0 - mm Hg

CASRN and Test Material	1332-21-4; chrysotile, crocidolite, or amosite

Confidentiality, Type, and Guideline	None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Temperature
System

Standard Deviation Results
Results Details

NR
NR
NR

approximate value





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Vapor Pressure

HERO ID: 3974865 Table: 1 of 1

Study Citation: NIOSH, (2016). NIOSH pocket guide to chemical hazards: Asbestos.

OECD Harmonized Vapor Pressure

Template:

HERO ID: 3974865

Parameter

Data

EXTRACTION

Vapor Pressure

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details

ca. 0 - mm Hg

1332-21-4; Asbestos

None; Not specified; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Approximate value.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features

and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

Medium

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Metric 6: Models N/A Not applicable. Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: None cited.

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Asbestos

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April 2024

Vapor Pressure

HERO ID: 9109830 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

NIOSH, (2019). NIOSH pocket guide to chemical hazards: Asbestos.
Vapor Pressure

9109830

Parameter

EXTRACTION

Data

Vapor Pressure
CASRN and Test Material

Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details

ca 0 mm Hg

1332-21-4; Actinolite, Actinolite asbestos, Amosite (cummingtonite-grunerite), Anthophyllite, Anthophyllite asbestos, Chrysotile.Crocidolite (Riebeckite),
Tremolite, Tremolite asbestos
none; not specified; not specified
NR; NR; NR; NR

NR; NR; NR; NR Notes: Hydrated mineral silicates

Not Reported

Not Reported

Not Reported

approximate

Domain



Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Primary reference not reported in this secondary source.

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Asbestos

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April 2024

Water Solubility

HERO ID: 786664 Table: 1 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Water Solubility

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Water Solubility	insoluble -

CASRN and Test Material	12001-29-5; chrysotile

Confidentiality, Type, and Guideline	none; not specified; not specified

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	NR; NR; NR; NR Notes: NR

Temperature	not specified

System	not specified

pH	not specified

Results Details Method	not specified

Standard Deviation Results	not specified

Results Details	Insoluble in water; insoluble in organic solvents; solubility in acids: 56.00% loss in weight due to loss of counter-ions, silicate structure remains

intact; solubility in bases: 1.03% loss in weight due to loss of counter-ions, silicate structure remains intact.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Water Solubility

HERO ID: 786664 Table: 2 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Water Solubility

786664

Parameter

EXTRACTION

Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

pH

Results Details Method
Standard Deviation Results
Results Details

insoluble -

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not specified

not specified

not specified

not specified

not specified

Insoluble in water; insoluble in organic solvents; solubility in acids: 3.14% loss in weight due to loss of counter-ions, silicate structure remains
intact; solubility in bases: 1.20% loss in weight due to loss of counter-ions, silicate structure remains intact.

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Water Solubility

HERO ID: 786664 Table: 3 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Water Solubility

786664

Parameter

EXTRACTION

Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

pH

Results Details Method
Standard Deviation Results
Results Details

insoluble -

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not specified

not specified

not specified

not specified

not specified

Insoluble in water; insoluble in organic solvents; solubility in acids: 12.00% loss in weight due to loss of counter-ions, silicate structure remains
intact; solubility in bases: 6.82% loss in weight due to loss of counter-ions, silicate structure remains intact.

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos	Water Solubility	HERO ID: 786664 Table: 4 of 5

Study Citation:	ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).

OECD Harmonized Water Solubility

Template:

HERO ID:	786664

EXTRACTION

Parameter	Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

pH

Results Details Method
Standard Deviation Results
Results Details

insoluble -

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not specified

not specified

not specified

not specified

not specified

Insoluble in water; insoluble in organic solvents.

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Water Solubility

HERO ID: 786664 Table: 5 of 5

Study Citation:
OECD Harmonized
Template:

HERO ID:

ATSDR, (2001). Toxicological profile for asbestos (Update, September 2001).
Water Solubility

786664

Parameter

EXTRACTION

Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

pH

Results Details Method
Standard Deviation Results
Results Details

insoluble -

17068-78-9; anthophyllite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not specified

not specified

not specified

not specified

not specified

Insoluble in water; insoluble in organic solvents; solubility in acids: 2.13% loss in weight due to loss of counter-ions, silicate structure remains
intact; solubility in bases: 1.77% loss in weight due to loss of counter-ions, silicate structure remains intact.

Domain



Metric

EVALUATION

Rating Comments

Domain 1: Substance









Metric 1:

Representativeness

High Data are measured or estimated for the subject chemical substance.



Metric 2:

Appropriateness

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Water Solubility

HERO ID: 3860485 Table: 1 of 1

Study Citation: (2017). PubChem: Chrysotile.
OECD Harmonized Water Solubility
Template:

HERO ID: 3860485

Parameter

Data

EXTRACTION

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Results Details Method
Standard Deviation Results
Results Details

Not Reported

12001-29-5; Chrysotile

none; experimental; not reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

25C

dissolution of chrysotile in water
not reported
continuous extraction
Not Reported

activity product of chrysotile in water =

1E-51.0

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features;

however standard water solubility was not assessed.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Callahan, M.A., M. W. Slimak, N. W. Gabel, et al. Water-Related Environmental Fate of 129 Priority Pollutants. Volume I. EPA-440/4 79-029a. Washington, DC:
U.S. Environmental Protection Agency, December 1979., p. 7-8

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Water Solubility

HERO ID: 3860486 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Crocidolite.
Water Solubility

3860486

Parameter

EXTRACTION

Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

insoluble in water

12001-28-4; crocidolite

none; experimental; not reported

NR; NR; NR; NR

NR; NR; solid; NR Notes: NR

Results Details Method
Standard Deviation Results
Results Details

NR
NR
NR
NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Citing CAMEO Chemicals and ILO-ICSC.

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Water Solubility

HERO ID: 3975020 Table: 1 of 1

Study Citation: USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.

OECD Harmonized Water Solubility

Template:

HERO ID: 3975020

EXTRACTION

Parameter Data

Water Solubility

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Results Details Method
Standard Deviation Results
Results Details

Not Reported

12001-29-5; Chrysotile

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Not Reported

After prolonged exposure to water, especially at high temperatures, slow progressive leaching of metal and silicate components occurs. The brucite
later of chrysotile fibers will dissolve and increase the pH of the solution. The equilibrium pH for the aqueous chrysotile slurry is 10.0 - 10.5.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features
(e.g., presence of certain functional groups) and/or other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Cites S. Speil and J. P. Leinerveber, Environ. Res. 2(3), 166 (1969). HEROID 5353620

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Refractive Index

HERO ID: 3647242 Table: 1 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.54-1.55

12001-29-5; chrysotile

none; experimental; not reported

NR; NR; NR; NR

None; NR; fiber; NR

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3647242 Table: 2 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.70-1.71

12001-28-4; crocidolite
none; experimental; not reported
NR; NR; NR; NR

None; NR; fiber; NR Notes: riebeckite
Not Reported
Not Reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3647242 Table: 3 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.67-1.70

12172-73-5; cummingtonite-grunerite
none; experimental; not reported
NR; NR; NR; NR

None; NR; fiber; NR Notes: amosite
Not Reported
Not Reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3647242 Table: 4 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.61 - 1.63

17068-78-9; anthophyllite
none; experimental; not reported
NR; NR; NR; NR
None; NR; fiber; NR
Not Reported
Not Reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Refractive Index

HERO ID: 3647242 Table: 5 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.60-1.64

14567-73-8; tremolite

none; experimental; not reported

NR; NR; NR; NR

None; NR; fiber; NR

Not Reported

Not Reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3647242 Table: 6 of 6

Study Citation:
OECD Harmonized
Template:

HERO ID:

Anonymous (1989). NIOSH Manual of Analytical Methods, (3rd Edition 3rd Supplement). NIOSH(NIOSH):89-127.
Refractive Index

3647242

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.62-1.68

13768-00-8; actinolite

none; experimental; not reported

NR; NR; NR; NR

None; NR; fiber; NR

Not Reported

Not Reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features or

other physical/chemical properties.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field and are broadly available to the public for review.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos Refractive Index HERO ID: 3827307 Table: 1 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.61

77536-67-5; Anthophyllite

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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April 2024

Refractive Index

HERO ID: 3827307 Table: 2 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.63

77536-66-4; Actinolite

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

Weakly pleochroic

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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April 2024

Asbestos Refractive Index HERO ID: 3827307 Table: 3 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.50-1.55

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 342 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 3827307 Table: 4 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.64

12172-73-5; Amosite

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 343 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 3827307 Table: 5 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.7

12001-28-4; Crocidolite

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

Pleochroic

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 344 of 522

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April 2024

Asbestos Refractive Index HERO ID: 3827307 Table: 6 of 6

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Refractive Index

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.61

77536-68-6; Tremolite

None; Experimental; Not reported

NR; NR; NR; NR

Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 345 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 785518 Table: 1 of 5

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Refractive Index
Template:

HERO ID: 785518

EXTRACTION

Parameter Data

Refractive Index ca. 1.70 (parallel to elongation) - ca. 1.71 (perpendicular to elongation)

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline none; not specified; not specified

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; fibers; NR Notes: NR

Temperature NR

System NR

Standard Deviation Results NR

Results Details NR

Results Details Methods NR

Parameter NR

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Data also reported in HERO ID 3647242.

Page 346 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 785518 Table: 2 of 5

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Refractive Index
Template:

HERO ID: 785518

EXTRACTION

Parameter

Data

Refractive Index

ca. 1.54 (parallel to elongation) - ca.

1.55 (perpendicular to elongation)

CASRN and Test Material

12001-29-5; Chrysotile-asbestos

Confidentiality, Type, and Guideline

none; not specified; not specified

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; fibers; NR Notes: NR

Temperature

not reported

System

not reported

Standard Deviation Results

not reported

Results Details

not reported

Results Details Methods

not reported

Parameter

not reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness

High

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased

(Method Objectivity)

towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

Low

The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Data also reported in HERO ID 3647242.

Page 347 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 785518 Table: 3 of 5

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Refractive Index
Template:

HERO ID: 785518

EXTRACTION

Parameter

Data

Refractive Index

ca. 1.64-1.68 (parallel to elongation) -

ca. 1.62-1.67 (perpendicular to elongation)

CASRN and Test Material

77536-66-4; Actinolite

Confidentiality, Type, and Guideline

none; not specified; not specified

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; fibers; NR Notes: NR

Temperature

not reported

System

not reported

Standard Deviation Results

not reported

Results Details

not reported

Results Details Methods

not reported

Parameter

not reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured or estimated for the subject chemical substance.

Metric 2:

Appropriateness

High

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased

(Method Objectivity)

towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

Low

The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Data also reported in HERO ID 3647242.

Page 348 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 785518 Table: 4 of 5

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Refractive Index
Template:

HERO ID: 785518

Parameter

Data

EXTRACTION

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

ca. 1.61 - ca. 1.63

77536-67-5; Anthophyllite-Asbestos

none; not specified; not specified

NR; NR; NR; NR

NR; NR; fibers; NR Notes: NR

not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Data also reported in HERO ID 3647242.

Page 349 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 785518 Table: 5 of 5

Study Citation: Bailey, K. F., Kelse, J., Wylie, A. G., Lee, R. J. (2006). The asbestiform and prismatic mineral growth habit and their relationship to cancer studies: A

pictorial presentation.

OECD Harmonized Refractive Index
Template:

HERO ID: 785518

Parameter

Data

EXTRACTION

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

ca. 1.60-1.62 (perpendicular to elongation) - ca. 1.62-1.64 (parallel to elongation)

77536-68-6; Tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; fibers; NR Notes: NR

not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Data also reported in HERO ID 3647242.

Page 350 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 7924810 Table: 1 of 4

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized Refractive Index

Template:

HERO ID: 7924810

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.545 - 1.553

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not Reported

1 range for n(gamma) was reported in Reaxys.
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Selfrige, G. C.; American Mineralogist; vol. 21; (1936); p. 477

Page 351 of 522

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April 2024

Asbestos	Refractive Index	HERO ID: 7924810 Table: 2 of 4

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized Refractive Index

Template:

HERO ID:	7924810

EXTRACTION

Parameter	Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.547-

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not reported

Not Reported

2 values for Ng were reported in Reaxys; one value was measured at 422.7 nm.
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Korytkova; Pivovarova; Drosdova; Gusarov; Russian lournal of General Chemistry; vol. 77; nb. 10; (2007); p. 1669 - 1676; Korytkova; Maslov; Pivovarova;
Polegotchenkova; Povinich;Gusarov; Inorganic Materials; vol. 41; nb. 7; (2005); p. 743 - 749

Page 352 of 522

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April 2024

Asbestos	Refractive Index	HERO ID: 7924810 Table: 3 of 4

Study Citation:	Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized Refractive Index

Template:

HERO ID:	7924810

EXTRACTION

Parameter	Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.542-

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not reported

Not Reported

2 values for N(p) were reported in Reaxys.
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Korytkova; Pivovarova; Drosdova; Gusarov; Russian lournal of General Chemistry; vol. 77; nb. 10; (2007); p. 1669 - 1676; Korytkova; Maslov; Pivovarova;
Polegotchenkova; Povinich;Gusarov; Inorganic Materials; vol. 41; nb. 7; (2005); p. 743 - 749

Page 353 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 7924810 Table: 4 of 4

Study Citation: Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.

OECD Harmonized Refractive Index

Template:

HERO ID: 7924810

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.532- 1.544

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not Reported

1 range for n(alpha) was reported in Reaxys.
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Selfrige, G. C.; American Mineralogist; vol. 21; (1936); p. 477

Page 354 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 7924816 Table: 1 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Richterite.
Refractive Index

7924816

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.594

17068-76-7; Richterite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported

n(p). 1 value reported in Reaxys.
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Korytkova, E. N.; Romanov, D. P.; Makarova, T. A.; Grebenshchikov, R. G.; InorganicMaterials; vol. 22; (1986); p. 1315
Neorganicheskie Materialy; vol. 22; (1986); p. 1500 - 1505

1320; Izvestiya Akademii Nauk SSSR,

Page 355 of 522

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Asbestos

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April 2024

Refractive Index

HERO ID: 7924816 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Richterite.
Refractive Index

7924816

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.606

17068-76-7; Richterite

None; Experimental; Not reported

NR; NR; NR; NR

NR; NR; Solid; NR

Not reported

Not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported

n(g). 1 value reported in Reaxys.
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Korytkova, E. N.; Romanov, D. P.; Makarova, T. A.; Grebenshchikov, R. G.; InorganicMaterials; vol. 22; (1986); p. 1315
Neorganicheskie Materialy; vol. 22; (1986); p. 1500 - 1505

1320; Izvestiya Akademii Nauk SSSR,

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Asbestos

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April 2024

Refractive Index

HERO ID: 6874055 Table: 1 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.493 - 1.562
12001-29-5; Chrysotile

None; Calculation; NA; dispersion staining method. Analytical method used cited as Ref. 1: Lott, P. F. (1989). Correlating dispersion staining
colors to the numerical value of the refractive index for asbestos fibers. Microchemical journal, 39(2), 145-148.

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.493 - 1.560; gamma = 1.517 - 1.562
Not Reported

Extinction: parallel; refractive index = refractive index oil + correction factor; correction factor determined from annular stop and central stop
colors and the wavelength the colors were observed at.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6874055 Table: 2 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.654- 1.717
12001-28-4; Crocidolite

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.654- 1.701; gamma = 1.668- 1.717
Not Reported

Extinction: inclined; refractive index = refractive index oil + correction factor; correction factor determined from annular stop and central stop
colors and the wavelength the colors were observed at.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Refractive Index

HERO ID: 6874055 Table: 3 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.599- 1.688
12172-67-7; Actinolite

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.599 - 1.668; gamma = 1.622 - 1.688
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Refractive Index

HERO ID: 6874055 Table: 4 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.596- 1.676

17068-78-9; Anthophyllite

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.596 - 1.652; gamma = 1.615 - 1.688
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Refractive Index

HERO ID: 6874055 Table: 5 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.635 - 1.729
12172-73-5; Amosite

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.635 - 1.696; gamma = 1.655 - 1.729
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Refractive Index

HERO ID: 6874055 Table: 6 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lott, P. E. (2002). Correlating dispersion staining colors to the numerical value of the refractive index for asbestos fibers - an update. Microchemical
Journal 72(3):251-254.

Refractive Index

6874055

Parameter

EXTRACTION

Data

Refractive Index
CASRN and Test Material
Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Temperature
System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.599- 1.688
14567-73-8; Tremolite

NA; NR; NR; NR

NA; NIST reference material; Solid; NR Notes: NR
NR

Not Reported
Not Reported

alpha = 1.599 - 1.668; gamma = 1.622 - 1.688
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

The analytical method was reported elsewhere.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos Refractive Index HERO ID: 6866754 Table: 1 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.493 - 1.560

12001-29-5; Chrysotile

None; Experimental; Not reported

NR; NR; NR; NR

Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

refractive index range measured parallel to fiber length was 1.517-1.562
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 363 of 522

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April 2024

Asbestos Refractive Index HERO ID: 6866754 Table: 2 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.635 - 1.696

12172-73-5; Amosite

None; Experimental; Not reported

NR; NR; NR; NR

Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

refractive index range measured parallel to fiber length was 1.655-1.729
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 364 of 522

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April 2024

Asbestos Refractive Index HERO ID: 6866754 Table: 3 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.654- 1.701

12001-28-4; Crocidolite

None; Experimental; Not reported

NR; NR; NR; NR

Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

refractive index range measured perpendicular to fiber length was 1.668-1.717
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 365 of 522

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April 2024

Asbestos Refractive Index HERO ID: 6866754 Table: 4 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.596- 1.652

77536-67-5; Anthophyllite
None; Experimental; Not reported
NR; NR; NR; NR
NR; NR; NR; NR
Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

refractive index range measured parallel to fiber length was 1.615-1.676
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 366 of 522

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April 2024

Asbestos Refractive Index HERO ID: 6866754 Table: 5 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.599- 1.668

77536-68-6; Tremolite

None; Experimental; Not reported

NR; NR; NR; NR

Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

Tremolite-actinolite reported together; refractive index range measured parallel to fiber length was 1.622-1.688
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 367 of 522

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April 2024

Asbestos Refractive Index HERO ID: 6866754 Table: 6 of 6

Study Citation: Lott, P. F. (1989). Correlating dispersion staining colors to the numerical value of the refractive-index for asbestos fibers. Microchemical Journal 39(2):145-

148.

OECD Harmonized Refractive Index
Template:

HERO ID: 6866754

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.599- 1.668

77536-66-4; Actinolite

None; Experimental; Not reported

NR; NR; NR; NR

Not reported

slopes of the dispersion curves at wavelengths of 400-700 nm were studied to obtain a set of correction values to assist in the determination of the
true refractive index
Not reported

Tremolite-actinolite reported together; refractive index range measured parallel to fiber length was 1.622-1.688
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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April 2024

Refractive Index

HERO ID: 3860485 Table: 1 of 1

Study Citation: (2017). PubChem: Chrysotile.

OECD Harmonized Refractive Index
Template:

HERO ID: 3860485

Parameter

Data

EXTRACTION

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported

Index of refraction: 1.53-1.56
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

* Related References: Source: Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V3 (1992) 671 (not a
primary source)

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April 2024

Refractive Index

HERO ID: 7924733 Table: 1 of 1

Study Citation: NLM, (2021). PubChem: Hazardous Substance Data Bank: Chrysotile, 12001-29-5.

OECD Harmonized Refractive Index

Template:

HERO ID: 7924733

EXTRACTION

Parameter Data

Refractive Index 1.53 - 1.56

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Temperature Not reported

System Not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not Reported
Not Reported
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

The methodology is unknown, but method bias appears unlikely.

The analytic method is unknown but is expected to be appropriate based on the study's
inclusion in a peer-reviewed database.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Data is from a publicly available and peer-reviewed database.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Virta R; Asbestos. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 15 Jul 2011

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April 2024

Refractive Index

HERO ID: 3582855 Table: 1 of 2

Study Citation:

OECD Harmonized
Template:

HERO ID:

Seshan, K. (1983). How are the physical and chemical properties of chrysotile asbestos altered by a 10-year residence in water and up to 5 days in simulated
stomach acid?. Environmental Health Perspectives 53(NOV):143-148.

Refractive Index

3582855

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details

Results Details Methods
Parameter

1.5 - 1.54

12001-29-5; Chrysotile asbestos
None; Experimental; Not reported
NR; NR; NR; NR

No; International Union Against Cancer (UICC); National Institute of Environmental Health Sciences (NIEHS); Globe, AZ.; NR; NR
Not reported

globe chrysotile fibers exposed approx. 600 h (from figure) to simulated gastric juice (NaCl, pepsin (hog extract), and HC1 added to distilled
water). pH of 1.2.

Not reported

Refractive index along and perpendicular to the fiber axis decreased from approx. 1.54 to 1.5 over 600 hours exposure (from figure) measured by
X-ray and electron diffraction.

Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos Refractive Index HERO ID: 3582855 Table: 2 of 2

Study Citation: Seshan, K. (1983). How are the physical and chemical properties of chrysotile asbestos altered by a 10-year residence in water and up to 5 days in simulated

stomach acid?. Environmental Health Perspectives 53(NOV):143-148.

OECD Harmonized Refractive Index
Template:

HERO ID: 3582855

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.44- 1.485

12001-29-5; Chrysotile asbestos
None; Experimental; Not reported
NR; NR; NR; NR

No; International Union Against Cancer (UICC); National Institute of Environmental Health Sciences (NIEHS); Globe, AZ.; NR; NR
Not reported

globe chrysotile fibers exposed approx. 600 h (from figure) to IN HC1.

Not reported

Refractive index decreased from approx. 1.485 to 1.44 over 600 hours exposure (from figure) measured by X-ray and electron diffraction.
Not Reported
Not Reported

EVALUATION

Domain Metric Rating Comments

Domain 1: Substance

Metric 1: Representativeness High Data are measured or estimated for the subject chemical substance.

Metric 2: Appropriateness N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Refractive Index

HERO ID: 3827272 Table: 1 of 4

Study Citation:

OECD Harmonized
Template:

HERO ID:

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System
(IRIS).

Refractive Index
3827272

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

= 1.600 (alpha) - = 1.688 (gamma)

77536-66-4; Actinolite
none; not specified; not specified
NR; NR; NR; NR

NR; NR; NR; NR Notes: Optical and crystallographic properties of fibrous amphiboles associated with Libby Amphibole asbestos
not reported
not reported
not reported

Refractive indices: alpha = 1.600-1.628, 1.612-1.668, 1.613-1.628, 1.6126; gamma 1.625-1.655, 1.635-1.688, 1.638-1.655, 1.6393
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

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Refractive Index

HERO ID: 3827272 Table: 2 of 4

Study Citation:

OECD Harmonized
Template:

HERO ID:

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System
(IRIS).

Refractive Index
3827272

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

= 1.605 (alpha) - = 1.641 (gamma)

17068-76-7; Richerite
none; not specified; not specified
NR; NR; NR; NR

NR; NR; NR; NR Notes: Optical and crystallographic properties of fibrous amphiboles associated with Libby Amphibole asbestos
not reported
not reported
not reported

Refractive indices: alpha = 1.622-1.623, 1.605-1.624, 1.615; gamma = 1.638-1.639, 1.627-1.641, 1.636
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: www.minsocam.oeg/msa/Handbook/Richterite.PDF.;ww.webmineral.com/data/Richterite.shtml.

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Refractive Index

HERO ID: 3827272 Table: 3 of 4

Study Citation:

OECD Harmonized
Template:

HERO ID:

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System
(IRIS).

Refractive Index
3827272

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

= 1.599 (alpha) - = 1.655 (gamma)

14567-73-8; Tremolite
none; not specified; not specified
NR; NR; NR; NR

NR; NR; NR; NR Notes: Optical and crystallographic properties of fibrous amphiboles associated with Libby Amphibole asbestos
not reported
not reported
not reported

Refractive indices: alpha = 1.600-1.628, 1.604-1.612, 1.599-1.612, 1.6063; gamma 1.625-1.655, 1.627-1.635, 1.625-1.637, 1.6343
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

Medium
N/A

The data are from a source that is known but is missing elements required for High
designation such as peer-review, public availability, or the inclusion of references to
original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

Medium

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Refractive Index

HERO ID: 3827272 Table: 4 of 4

Study Citation:

OECD Harmonized
Template:

HERO ID:

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System
(IRIS).

Refractive Index
3827272

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

= 1.618 (alpha) - = 1.658 (gamma)

12425-92-2; Winchite
none; not specified; not specified
NR; NR; NR; NR

NR; NR; NR; NR Notes: Optical and crystallographic properties of fibrous amphiboles associated with Libby Amphibole asbestos
not reported
not reported
not reported

Refractive indices: alpha = 1.618-1.626, 1.618-1.621, 1.629, 1.636; gamma = 1.634-1.642, 1.634-1.637, 1.650, 1.658
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Bandli et al. (2003) Optical, compositional, morphological, and x-ray data on eleven particles of amphibole from Libby, MT, U.S.A. Canadian Mineralogist 41:
1241 — 1253. (HERO ID 713658); Wylie and Verkouteren (2000) Amphibole asbestos from Libby, MT: Aspects of nomenclature. American Mineralogist, 85: 1540—1542.(HERO ID
713648); www.minsocam.oeg/msa/HandbookAVinchite.PDF.;www.mindat.org/min-4296.html.

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Refractive Index

HERO ID: 6887461 Table: 1 of 1

Study Citation:

OECD Harmonized
Template:

HERO ID:

Verkouteren, J. R., Wylie, A. G., Steel, E. B., Lim, M. S. (1995). Analysis of the tremolite/actinolite series using high precision refractive index measure-
ments. Microbeam Analysis :27-28.

Refractive Index

6887461

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.626- 1.684
1332-21-4; Asbestos
None; Experimental; other
NR; NR; NR; NR

NR; NR; NR; NR Notes: tremolite-actinolite
Not reported

Used the spindle stage to measure principal refractive indices of individual fibers or particles with an accuracy of ±0.0005
Not reported

results taken from figure; plot of gamma-refractive index vs Mg/Mg+Fe
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3859385 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Refractive Index

3859385

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.60-1.64

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not reported

not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

not reported
not reported
not reported
not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Refractive Index

HERO ID: 3859385 Table: 2 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Refractive Index

3859385

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.53 - 1.56

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

not reported
not reported
not reported
not reported

Domain

Metric

EVALUATION

Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3859385 Table: 3 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Refractive Index

3859385

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.65 - 1.72

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

not reported
not reported
not reported
not reported

Domain

Metric

EVALUATION

Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 3859385 Table: 4 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Refractive Index

3859385

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

1.63 - 1.73

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

not reported

Standard Deviation Results
Results Details
Results Details Methods
Parameter

not reported
not reported
not reported
not reported

Domain

Metric

EVALUATION

Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 1 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.641 - 1.677
77536-66-4; Actinolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased

(Method Objectivity)

Metric 4: Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Refractive Index

HERO ID: 6860096 Table: 2 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.683 - 1.700

77536-67-5; Anthophyllite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Refractive Index

HERO ID: 6860096 Table: 3 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.537 - 1.554
12001-29-5; Chrysotile
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Refractive Index

HERO ID: 6860096 Table: 4 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.545 - 1.557
12172-73-5; Amosite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 5 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.670- 1.675
12172-73-5; Amosite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 6 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.683 - 1.694
12001-28-4; Crocidolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 7 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.680- 1.692
12001-28-4; Crocidolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 8 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.596- 1.654

77536-67-5; Anthophyllite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Refractive Index

HERO ID: 6860096 Table: 9 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.599- 1.620
77536-68-6; Tremolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 390 of 522

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April 2024

Refractive Index

HERO ID: 6860096 Table: 10 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.622- 1.641
77536-68-6; Tremolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 391 of 522

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Refractive Index

HERO II): 6860096 Table: 11 of 11

Study Citation: Xu, X. M., Li, Y. Q., Belfiore, L. A., Tang, J. G. (2018). Polarized light microscope method for the determination of asbestos fiber of textile. Integrated

Ferroelectrics 188(1):136-147.

OECD Harmonized Refractive Index
Template:

HERO ID: 6860096

EXTRACTION

Parameter Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.619- 1.658
77536-66-4; Actinolite
None; Experimental; NA
NA; NR; NR; NR

NA; Health and Safety Laboratory, UK and KTR laboratory, South Korea; Solid; NR Notes: Asbestos-standard sample
NR

LV100 polarizing microscope and refractive index oil

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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Refractive Index

HERO ID: 6880237 Table: 1 of 2

Study Citation: Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.

OECD Harmonized Refractive Index

Template:

HERO ID: 6880237

EXTRACTION

Parameter Data

Refractive Index 1.625 - 1.645

CASRN and Test Material 12172-67-7; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Gemological properties and mineral compositions of black nephrite from Guangxi

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Temperature Not reported

System plate samples measured using a refractometer

Standard Deviation Results
Results Details
Results Details Methods
Parameter

Not reported

8 samples containing 65->98% actinolite
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Asbestos

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Refractive Index

HERO ID: 6880237 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.
Refractive Index

6880237

Parameter

EXTRACTION

Data

Refractive Index

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Temperature

System

Standard Deviation Results
Results Details
Results Details Methods
Parameter

1.647- 1.650
12172-67-7; Actinolite

None; Experimental; Gemological properties and mineral compositions of black nephrite from Guangxi
NR; NR; NR; NR
NR; NR; Solid; NR
Not reported

plate samples measured using a refractometer
Not reported

4 samples containing 60-99% ferro-actinolite
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Nanomaterial Zeta

HERO ID: 3080916 Table: 1 of 1

Study Citation: Keane, M. J., Stephens, J. W., Zhong, B. Z., Miller, W. E., Ong, T. M., Wallace, W. E. (1999). A study of the effect of chrysotile fiber surface composition

on genotoxicity in vitro, lournal of Toxicology and Environmental Health, Part A: Current Issues 57(8):529-541.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID: 3080916

EXTRACTION

Parameter Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

ca_lower -0.02 V (acid treated fibers; treated with 1 N HC1 for 2h) - ca_upper +0.02 V (untreated fibers) Other
12001-29-5; chrysotile asbestos
none; Experimental; not specified
deionized H20 (Millipore); NR; NR; NR

NR; National Institute of Environmental Health Sciences; solid; NR Notes: Intermediate-length chrysotile

not reported - not reported

not reported; not reported; not reported

other; not reported; not reported
Zeta-Meter ZM-80; not reported
not reported
5.0; deionized water

untreated fibers had a tendency to adhere to the side of the polystyrene containers, while the treated fibers formed large clumps in the middle of
the vial.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3078027 Table: 1 of 1

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lavkulich, L. M., Schreier, H. E., Wilson, J. E. (2014). Effects of natural acids on surface properties of asbestos minerals and kaolinite. Journal of
Environmental Science and Health, Part A: Toxic/Hazardous Substances & Environmental Engineering 49(6):617-624.

Nanomaterial Zeta

3078027

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

+21.5 mV/cm - Other
12172-67-7; Actinolite
None; Experimental; Not Reported
NR; NR; NR; NR

NA; VWR Int., Randor, PA, USA; Solid; NR Notes: Sample passed through a < 63 um stainless steel sieve and fine fraction retained for analysis
Not Reported

Not Reported; Not Reported; Not Reported

electrophoresis; Not Reported; Not Reported
Zeta Meter Model 3.0+; Mean of 5 samples
Not Reported
NR; NR
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Nanomaterial Zeta

HERO ID: 3084540 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and hemolytic activity of asbestos. Environmental Research 13(1): 135-145.
Nanomaterial Zeta

3084540

EXTRACTION

Parameter

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

+40.5 - +52.5 mV
12001-29-5; Chrysotile
None; Experimental; NA
Triple-distilled water; NR; NR; NR

NA; MRC Pneumoconiosis Unit, Pernarth, South Wales, and Johns-Manville Research and Development Center, Denver; Solid; NR Notes: DPPC
added to aqueous suspensions, pH adjusted with HC1 or NaOH, samples incubated for 1 day between 41 and 43 deg C in shaker bath and cooled
to room temperature prior to use.

Not Reported

Not Reported; Not Reported; Not Reported
electrophoresis; Not Reported; Not Reported

microelectrophoresis (Zeta Meter) and stereoscopic microscope.; Movement of fibers at least 0.1 um in size observed; the time required for 15 to
25 fibers to traverse 1 ocular-microscope was recorded; electrophoretic mobility was determined, and the Zeta potential was calculated from this
using the Helmholtz-Smoluchowski equation.

Not Reported

7.4; 100 mL distilled water with DPPC added, pH adjusted with HC1 or NaOH.

+40.5 and +52.5 mV for samples A and B

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Nanomaterial Zeta

HERO ID: 3084540 Table: 2 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and hemolytic activity of asbestos. Environmental Research 13(1): 135-145.
Nanomaterial Zeta

3084540

EXTRACTION

Parameter

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

-54.0 - mV

17068-78-9; Anthophyllite
None; Experimental; NA
Triple-distilled water; NR; NR; NR

Not Reported

Not Reported; Not Reported; Not Reported
electrophoresis; Not Reported; Not Reported

Not Reported

7.4; 100 mL distilled water with DPPC added, pH adjusted with HC1 or NaOH.

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Nanomaterial Zeta

HERO ID: 3084540 Table: 3 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and hemolytic activity of asbestos. Environmental Research 13(1): 135-145.
Nanomaterial Zeta

3084540

EXTRACTION

Parameter

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

-50.5 - mV

12001-28-4; Crocidolite
None; Experimental; NA
Triple-distilled water; NR; NR; NR

Not Reported

Not Reported; Not Reported; Not Reported
electrophoresis; Not Reported; Not Reported

Not Reported

7.4; 100 mL distilled water with DPPC added, pH adjusted with HC1 or NaOH.

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 399 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3084540 Table: 4 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and hemolytic activity of asbestos. Environmental Research 13(1): 135-145.
Nanomaterial Zeta

3084540

EXTRACTION

Parameter

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

-58.5 - mV
12172-73-5; Amosite
None; Experimental; NA
Triple-distilled water; NR; NR; NR

Not Reported

Not Reported; Not Reported; Not Reported
electrophoresis; Not Reported; Not Reported

Not Reported

7.4; 100 mL distilled water with DPPC added, pH adjusted with HC1 or NaOH.

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5: Databases
Metric 6: Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 400 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3616568 Table: 1 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and asbestos toxicity. Nature 265(5594):537-539.
Nanomaterial Zeta

3616568

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

+34.0 mV (leached with Tyrode's solution for 21d) - +44.5 mV (unleached)

12001-29-5; chrysotile A

none; Experimental; not reported

NR; NR; NR; NR

NR; reference sample from the International Union against Cancer; fibers; NR Notes: NR

not reported - not reported

not reported; not reported; not reported

electrophoresis; not reported; Electrophoretic mobility measured using a microelectrophoresis instrument (Zeta-Meter) and zeta potential was
approximated using the Helmholtz-Smoluchowski equation.

Zeta-meter; Electrophoretic mobility of fibres incubated for 2 hours as a 0.01% (w/v) distilled-water suspension was measured using a microelec-
trophoresis instrument (Zeta-Meter) and zeta potential was approximated using the Helmholtz-Smoluchowski equation,
not reported

7.4; 0.01% (w/v) distilled water solution (2 hour incubation prior to analysis)

Leaching time 1 day using mixtures 0.5% (w/v) suspensions in Tyrode's (physiological buffer) solution, 0.01M HC1 or 0.1M HC1.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 401 of 522

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Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Nanomaterial Zeta

HERO ID: 3616568 Table: 2 of 2

Study Citation:
OECD Harmonized
Template:

HERO ID:

Light, W. G., Wei, E. T. (1977). Surface charge and asbestos toxicity. Nature 265(5594):537-539.
Nanomaterial Zeta

3616568

EXTRACTION

Parameter

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

-43.5 mV (unleached) - +58.5 mV (leached with Tyrode's solution for 21d)

12001-28-4; amphibole crocidolite
none; Experimental; not reported
NR; NR; NR; NR

NR; reference sample from the International Union against Cancer; fibers; NR Notes: NR

not reported - not reported

not reported; not reported; not reported

electrophoresis; not reported; Electrophoretic mobility measured using a microelectrophoresis instrument (Zeta-Meter) and zeta potential was
approximated using the Helmholtz-Smoluchowski equation.

Zeta-meter; Electrophoretic mobility of fibres incubated for 2 hours as a 0.01% (w/v) distilled-water suspension was measured using a microelec-
trophoresis instrument (Zeta-Meter) and zeta potential was approximated using the Helmholtz-Smoluchowski equation,
not reported

7.4; 0.01% (w/v) distilled water solution (2 hour incubation prior to analysis)

Leaching time 1 day using mixtures 0.5% (w/v) suspensions in Tyrode's (physiological buffer) solution, 0.01M HC1 or 0.1M HC1.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:	Reliability/Unbiased

(Method Objectivity)

Metric 4:	Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





Page 402 of 522

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April 2024

Asbestos	Nanomaterial Zeta	HERO ID: 3982328 Table: 1 of 1

Study Citation:	NIH, (2016). Report on carcinogens: Asbestos.

OECD Harmonized Nanomaterial Zeta

Template:

HERO ID:	3982328

EXTRACTION

Parameter	Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Not specified - Not specified
1332-21-4; chrysotile
none; Not specified; Not Reported
NR; NR; NR; NR

NR; occurs naturally; solid; NR Notes: NR

Not specified - Not specified

Not specified; Not specified; Not specified

Not Reported; Not specified; Not specified
Not specified; Not specified
Not specified

Not specified; Not specified

fibers have a net positive surface charge

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review, use
and includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

* Related References: Cited sources (multiple sources cited) - IARC 1973, 1977, IPCS 1986

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Asbestos	Nanomaterial Zeta	HERO ID: 3086336 Table: 1 of 7

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta

Template:

HERO ID:	3086336

EXTRACTION

Parameter	Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Zeta potential (mV) of short fibers in Gambles solution at 37°C: -17(±4), -19(±5), and -20(±5) at pH 4.5, 5.5, and 7.0, respectively. - Zeta

potential (mV) of long fibers in Gambles solution at 37°C: -15(±5), -17(±4), and -17(±5), at pH 4.5, 5.5, and 7.0, respectively.

77536-88-6; Tremolite

none; Experimental; Non-guideline

Gamble's solution (concentration 0.1 wt%); NR; NR; NR

NR; Val d'Ala, Turin (Italy); samples were preliminary disaggregated in distilled water, using a common mechanical shredder;
(Cal.91Na0.06K0.01)1.98(Mg4.71Fe2+ 0.22Fe3+ 0.08Mn0.02)5.03(Si8.01A10.02)8.03022.14(OH)1.86 Notes: Short fiber samples: surface area
= 9.2±3 m2/g, fiber length = 11±1 nm; long fiber samples: surface area = 0.66±2 m2/g, fiber length = 78±1 |jm (determined using SEM)
Not reported - Not reported
Not reported; Not reported; Not reported

electrophoresis; Not specified; zeta potential of long and short fiber size classes determined both in organic Gamble's modified solution at 25°C

and 37°C, and pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples

Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

reported with values in parenthesis

pH range 3.0-11.0; Gamble's solution

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 404 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 2 of 7

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3086336

EXTRACTION

Parameter	Data

Zeta	Zeta potential (mV) of long fibers in water at 37°C: +26(±2), +19(±2), +10(±3), +12(±2), +8(±3), +4(±2), and -7(±4), at pH 4.0, 5.0, 6.0,

7.0, 8.0, 9.0, and 10.0, respectively. Zeta potential (mV) of long fibers in water at 25°C: +29(±3), +28(±3), +17(±3), +10(±3), +7(±4), +8(±5),
and -10(±4), at pH 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, and 10.0, respectively. - Zeta potential (mV) of long fibers in Gambles solution at 37°C: +4(±2),
-4(±3), -8(±3), -8(±3), -8(±3), -13(±2), -18(±5)and -21(±5), at pH 3.0, 4.0, 4.5, 6.0, 7.0, 8.0, 10.0, and 11.0, respectively. Zeta potential
(mV) of short fibers in Gambles solution at 37°C: -9(±6), -12(±3), -16(±3), -14(±5), -20(±2), -19(±4), -18(±2), -16(±5), -22(±4),
—20(±5), —20(±3), —20(±4), atpH 3.0, 3.5, 4.0, 4.5, 5.0, 5.5, 6.5, 7.0, 7.5, 8.0, 9.5, and 10.0, respectively.

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	none; Experimental; Non-guideline

Solvent, Reactivity, Storage, and Stability	double distilled water or Gamble's solution (concentration 0.1 wt%); NR; NR; NR

Radiolabel, Source, State, and Purity	NR; Quebec (Canada): UICC standard Chrysotile "B" Canadian NB #4173-111-1; samples were preliminary disaggregated in distilled water,

using a common mechanical shredder; (Mg5.93Fe2+ 0.11A10.02Fe3+ 0.01)6.07Si4.03010(OH)7.66 Notes: Short fiber samples: surface area =
42±1 m2/g, fiber length = 5±2 nm; long fiber samples: surface area = 29±1 m2/g, fiber length = 99±5 |jm (determined using SEM)

Isoelectric Value	Not reported - Not reported

Standard Deviation, Medium, and Remarks for Not reported; Not reported; Not reported
Isoelectric Point

Method Type, Sampling, and Additional Details electrophoresis; Not specified; zeta potential of long and short fiber size classes determined both in distilled water and in organic Gamble's modified

solution at 25°C and 37°C, and pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples
Instruments and Measurements Reproduced	Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

Standard Deviation	reported with values in parenthesis

pH and Medium	pH range 3.0-11.0; double distilled water or Gamble's solution

Results Details	Zeta potential (mV) in Gambles solution at 25°C and pH 4.0 of long fibers = — 8(±4).

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Continued on next page ...

Page 405 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 2 of 7

... continued from previous page

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3086336

EVALUATION

Domain	Metric	Rating	Comments

Overall Quality Determination	High

Page 406 of 522

-------
Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 3 of 7

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3086336

EXTRACTION

Parameter	Data

Zeta	Zeta potential (mV) of short fibers in water at 37°C: -16(±3), -31(±5), -34(±5), -38(±6), -34(±4), -36(±5), -37(±4), -39(±7), -37(±4),

—37(±5), —39(±5), and —42(±5), at pH 3.0, 4.0, 5.0, 6.0, 6.5, 7.0, 7.5, 8.0, 8.5, 9.0, 10.0, and 10.5, respectively. Zeta potential (mV) of short
fibers in water at 25°C: -16(±4), -26(±4), -32(±4), -36(±4), -38(±5), -40(±5), -43(±7), -43(±6), -45(±6), and -48(±6), at pH 3.0,
4.0, 4.5, 5.0, 6.5, 7.0, 8.0, 9.0, 10.0 and 10.5, respectively. - Zeta potential (mV) of long fibers in Gambles solution at 37°C: —20(±4), —23(±5),
—22(±4), and —20(±6), at pH 3.5, 4.5, 6.0, and 7.0, respectively. Zeta potential (mV) of short fibers in Gambles solution at 37°C: -21(4),
—23(±4), —28(±4), —21(±4), -29(±5), -28(±4), -24(±4), -31(±4), -21(±4), -30(±3), -17(±5), and -19(±4) at pH 3.0. 3.5, 4.0, 4.5,
5.0, 5.5, 7.0, 7.5, 8.0, 8.5, 9.0, and 10.0, respectively.

CASRN and Test Material	12001-28-4; Crocidolite

Confidentiality, Type, and Guideline	none; Experimental; Non-guideline

Solvent, Reactivity, Storage, and Stability	double distilled water or Gamble's solution (concentration 0.1 wt%); NR; NR; NR

Radiolabel, Source, State, and Purity	NR; Koegas Mine, Northern Cape (South Africa): UICC standard Crocidolite South African NB #4173-111-3; samples were

preliminary disaggregated in distilled water, using a common mechanical shredder; (Nal.96Ca0.03K0.01)2(Fe2+ 2.34Fe3+
2.05Mg0.52)4.91(Si7.84A10.02)7.86O21.36(OH)2.64 Notes: Short fiber samples: surface area = 16.1±6 m2/g, fiber length = 6±1 |jm;
long fiber samples: surface area = 11.5±4 m2/g, fiber length = 30±3 nm (determined using SEM)

Isoelectric Value	Not reported - Not reported

Standard Deviation, Medium, and Remarks for Not reported; Not reported; Not reported
Isoelectric Point

Method Type, Sampling, and Additional Details electrophoresis; Not specified; zeta potential of long and short fiber size classes determined both in distilled water and in organic Gamble's modified

solution at 25°C and 37°C, and pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples
Instruments and Measurements Reproduced	Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

Standard Deviation	reported with values in parenthesis

pH and Medium	pH range 3.0-11.0; double distilled water or Gamble's solution

Results Details	Zeta potential (mV) in Gambles solution at 25°C and pH 4.5 of short fibers = — 26(±5).

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Continued on next page ...

Page 407 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 3 of 7

... continued from previous page

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3086336

Domain Metric

EVALUATION

Rating

Comments

Overall Quality Determination

High





Page 408 of 522

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Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 4 of 7

Study Citation:	Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3086336

EXTRACTION

Parameter	Data

Zeta	Zeta potential (mV) of long fibers in Gambles solution at 37°C: -6(±8), —5(±3), and —15(±3), at pH 4.0, 4.5, and 7.0, respectively. Zeta

potential (mV) of short fibers in Gambles solution at 37°C: —15(±6), and —17(±4) at pH 4.5, and 7.0, respectively. - Zeta potential (mV) in
Gambles solution at 25°C and pH 4.5 of long fibers = —15(±5). Zeta potential (mV) in Gambles solution at 25°C and pH 4.5 of short fibers =
—20(±4).

CASRN and Test Material	77536-67-5; Anthophyllite

Confidentiality, Type, and Guideline	none; Experimental; Non-guideline

Solvent, Reactivity, Storage, and Stability	Gamble's solution (concentration 0.1 wt%); NR; NR; NR

Radiolabel, Source, State, and Purity	NR; Paakkila mine, Paakkila (Finland): UICC standard Anthophylite Finnish NB #4173-111-5; samples were preliminary disaggregated in distilled

water, using a common mechanical shredder; Ca0.04(Mg5.81Fe2+ 0.92Fe3+ 0.21Mn0.04)6.98(Si7.83A10.02)7.85021.63(OH)2.37 Notes: Short
fiber samples: surface area = 14.4±5 m2/g, fiber length = 17±2 |jm; long fiber samples: surface area = 4.4±2 m2/g, fiber length = 95±9 nm
(determined using SEM)

Isoelectric Value	Not reported - Not reported

Standard Deviation, Medium, and Remarks for Not reported; Not reported; Not reported
Isoelectric Point

Method Type, Sampling, and Additional Details electrophoresis; Not specified; zeta potential of long and short fiber size classes determined in organic Gamble's modified solution at 25°C and

37°C, and pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified
reported with values in parenthesis
pH range 3.0-11.0; Gamble's solution
Not Reported

Domain

Metric

EVALUATION

Rating Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A Rating of this factor is not applicable to this kind of information.
N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 409 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 5 of 7

Study Citation:

OECD Harmonized
Template:

HERO ID:

Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

Nanomaterial Zeta

3086336

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Zeta potential (mV) of short fibers in Gambles solution at 37°C: -27(±2), -27(±3),and -23(±2), at pH 4.5, 5.5, and 7.0, respectively. - Zeta

potential (mV) of long fibers in Gambles solution at 37°C: -26(±4), -21(±6), and -27(±7), at pH 4.5, 5.5, and 7.0, respectively.

12001-29-5; Chrysotile

none; Experimental; Non-guideline

Gamble's solution (concentration 0.1 wt%); NR; NR; NR

NR; Val Malenco, Sondrio (Italy); samples were preliminary disaggregated in distilled water, using a common mechanical shredder; (Mg5.85Fe2+

0.11A10.02Ni0.01)5.99Si4.01010(OH)7.86 Notes: Short fiber samples: surface area = 68±9 m2/g, fiber length = 10±5 |jm; long fiber samples:

surface area = 45±2 m2/g, fiber length = 160±9 |im (determined using SEM)

Not reported - Not reported

Not reported; Not reported; Not reported

electrophoresis; Not specified; zeta potential of long and short fiber size classes determined in organic Gamble's modified solution at 37°C, and

pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples

Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

reported with values in parenthesis

pH range 3.0-11.0; Gamble's solution

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 410 of 522

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 6 of 7

Study Citation:

OECD Harmonized
Template:

HERO ID:

Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

Nanomaterial Zeta

3086336

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Zeta potential (mV) of short fibers in Gambles solution at 37°C: -27(±3), -13(±9),and -27(±3), at pH 4.5, 5.5, and 7.0, respectively. - Zeta

potential (mV) of long fibers in Gambles solution at 37°C: +1(±5), -12(±5), -18(±5), -23(±4), -19(±5), -25(±4), -16(±2), -19(±2), -17(±4),

-17(±2), -15(±2), -16(±3), and -22(±3), atpH 3.0, 3.5, 4.0, 4.5, 5.0, 5.5, 6.5, 7.0, 7.5, 8.0, 9.0, 10.0, and 10.5, respectively.

12001-29-5; Chrysotile

none; Experimental; Non-guideline

Gamble's solution (concentration 0.1 wt%); NR; NR; NR

NR; Chrysotile Balangero (Italy); samples were preliminary disaggregated in distilled water, using a common mechanical shredder; (Mg5.81Fe2+

0.21A10.27Fe3+ 0.03Cr0.01)6.33Si3.97010(OH)7.11 Notes: Short fiber samples: surface area = 43±2 m2/g, fiber length = 6±1 nm; long fiber

samples: surface area = 24.8±9 m2/g, fiber length = 65±3 nm (determined using SEM)

Not reported - Not reported

Not reported; Not reported; Not reported

electrophoresis; Not specified; zeta potential of long and short fiber size classes determined in organic Gamble's modified solution at 37°C, and

pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples

Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

reported with values in parenthesis

pH range 3.0-11.0; Gamble's solution

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 411 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3086336 Table: 7 of 7

Study Citation:

OECD Harmonized
Template:

HERO ID:

Pollastri, S., Gualtieri, A. F., Gualtieri, M. L., Hanuskova, M., Cavallo, A., Gaudino, G. (2014). The zeta potential of mineral fibres. Journal of Hazardous

Materials 276:469-479.

Nanomaterial Zeta

3086336

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

Zeta potential (mV) of short fibers in Gambles solution at 37°C: -16(4), -19(±4), -21 (±4), -20(±5), -21(±4), -21(±4), -25(±3), -21(±7),

—14(±7), —15(±6), and —18(±5) atpH 3.0, 4.0, 4.5, 5.0, 6.5, 7.0, 7.5, 8.0, 8.5, 9.0, and 10.0, respectively. - Zeta potential (mV) of long fibers in

Gambles solution at 37°C: —13(±3), —23(±8), and —24(±5), at pH 4.5, 5.5, and 7.0, respectively.

12172-73-5; Amosite

none; Experimental; Non-guideline

Gamble's solution (concentration 0.1 wt%); NR; NR; NR

NR; Penge mine, Northern Province (South Africa); samples were preliminary disaggregated in distilled water, using a common mechanical
shredder; (Ca0.02Na0.01)(Fe2+ 5.36Mgl.48Fe3+ 0.11Mn0.06)7.01(Si7.93A10.01)7.94021.94(C)H)2.06 Notes: Short fiber samples: surface area
= 9.5±3 m2/g, fiber length = 7±2 nm; long fiber samples: surface area = 3.9±1 m2/g, fiber length = 125±9 nm (determined using SEM)
Not reported - Not reported
Not reported; Not reported; Not reported

electrophoresis; Not specified; zeta potential of long and short fiber size classes determined in organic Gamble's modified solution at 25°C and

37°C, and pH 3-10.5 (±0.2, pH adjusted using HCL and NaOH); triplicate measurements performed for several samples

Zeta potential measured using a Zetasizer Nano Series instrument (Malvern); Not specified

reported with values in parenthesis

pH range 3.0-11.0; Gamble's solution

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 412 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 7475373 Table: 1 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Schiller, J. E., Payne, S. L. (1980). Surface charge measurements of amphibole cleavage fragments and fibres.
Nanomaterial Zeta

7475373

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

ca_lower -59 - ca_upper -38 mV
77536-67-5; anthophyllite asbestos
none; Experimental; none

distilled water; Not Reported; Not Reported; Not Reported

Not Reported; UICC International Union Against Canter; Origin: Finland; Not Reported; ACS reagent grade
Not Reported

Not Reported; Not Reported; Not Reported

electrophoresis; zeta potential was calculated using the Helmholtz-Smoluchowski equation; microelectrophoresis

Zeta Meter cell; Only particles aligned axially to the electric field were timed, and the average electrophoretic mobility was calculated from the
average velocity.

Not Reported
5-9; distilled water

zeta potentials of fibrous asbestiform minerals from graph: ca. -40, -51, -58, -58, and -59 at pH values of 5, 6, 7, 8, and 9, respectively; zeta
potential (mV) of blocky particles = 39±2 and elongated particles = 49±2 at pH 7

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 413 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 7475373 Table: 2 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Schiller, J. E., Payne, S. L. (1980). Surface charge measurements of amphibole cleavage fragments and fibres.
Nanomaterial Zeta

7475373

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

ca_lower -41 - ca_upper -20 mV
12001-28-4; Crocidolite
none; Experimental; none

distilled water; Not Reported; Not Reported; Not Reported

Not Reported; UICC International Union Against Cancer; Not Reported; ACS reagent grade
Not Reported

Not Reported; Not Reported; Not Reported

electrophoresis; zeta potential was calculated using the Helmholtz-Smoluchowski equation; microelectrophoresis

Zeta Meter cell; Only particles aligned axially to the electric field were timed, and the average electrophoretic mobility was calculated from the
average velocity.

Not Reported
5-9; distilled water

zeta potentials of fibrous asbestiform minerals from graph: ca. -20, -32, -41, -40, and -41 at pH values of 5, 6, 7, 8, and 9, respectively; zeta
potential (mV) of blocky particles = 28±1 and elongated particles = 39±1 at pH 7

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 414 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 7475373 Table: 3 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Schiller, J. E., Payne, S. L. (1980). Surface charge measurements of amphibole cleavage fragments and fibres.
Nanomaterial Zeta

7475373

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

ca_lower -55 - ca_upper -25 mV
12172-73-5; amosite
none; Experimental; none

distilled water; Not Reported; Not Reported; Not Reported

Not Reported; UICC International Union Against Canter; Origin: Africa; Not Reported; ACS reagent grade
Not Reported

Not Reported; Not Reported; Not Reported

electrophoresis; zeta potential was calculated using the Helmholtz-Smoluchowski equation; microelectrophoresis

Zeta Meter cell; Only particles aligned axially to the electric field were timed, and the average electrophoretic mobility was calculated from the
average velocity.

Not Reported
5-9; distilled water

zeta potentials of fibrous asbestiform minerals from graph: ca. -25, -35, -36, -50, and -55 at pH values of 5, 6, 7, 8, and 9, respectively; zeta
potential (mV) of blocky particles = 24±3 and elongated particles = 37±2 at pH 7

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 415 of 522

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Asbestos

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Nanomaterial Zeta

HERO ID: 7475373 Table: 4 of 4

Study Citation:
OECD Harmonized
Template:

HERO ID:

Schiller, J. E., Payne, S. L. (1980). Surface charge measurements of amphibole cleavage fragments and fibres.
Nanomaterial Zeta

7475373

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

ca_lower -46 (India); -50 (Switzerland) - ca_upper -32(India); -36 (Switzerland) mV
77536-68-6; tremolite asbestos
none; Experimental; none

distilled water; Not Reported; Not Reported; Not Reported

Not Reported; BuMines - Origin: India; University of Minnesota, Minneapolis, Minn - Origin: Switzerland; Not Reported; ACS reagent grade
Not Reported

Not Reported; Not Reported; Not Reported

electrophoresis; zeta potential was calculated using the Helmholtz-Smoluchowski equation; microelectrophoresis

Zeta Meter cell; Only particles aligned axially to the electric field were timed, and the average electrophoretic mobility was calculated from the
average velocity.

Not Reported
5-9; distilled water

zeta potentials of fibrous asbestiform minerals from graph (India): ca. -32, -36, -42, -44, and -46 at pH values of 5, 6, 7, 8, and 9, respectively; zeta
potentials of fibrous asbestiform minerals from graph (Switzerland): ca. -36, -42, -46, -45, and -50 at pH values of 5, 6, 7, 8, and 9, respectively;
zeta potential (mV) of blocky particles = 24±1 and elongated particles = 35±3 at pH 7 (Switzerland)

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 416 of 522

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Asbestos

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Nanomaterial Zeta

HERO ID: 3975020 Table: 1 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Nanomaterial Zeta

3975020

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

+13.6- +54

1332-21-4; Chrysotile

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

NR - 11.8

Not Reported; Not Reported; Not Reported

Not Reported; NR; NR
NR; NR
Not Reported
NR; NR

Values become negative after weathering and/or leaching.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: No citations reported.

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3975020 Table: 2 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Nanomaterial Zeta

3975020

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

-20 - -40

12172-73-5; Amosite

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

NR-

Not Reported; Not Reported; Not Reported
Not Reported; NR; NR

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

NR; NR
Not Reported
NR; NR
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: No citations reported.

Page 418 of 522

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Asbestos

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April 2024

Nanomaterial Zeta

HERO ID: 3975020 Table: 3 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

USGS, (2002). Asbestos: Geology, mineralogy, mining, and uses.
Nanomaterial Zeta

3975020

Parameter

EXTRACTION

Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details

-32-

12001-28-4; Crocidolite

None; Experimental; NR

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

NR-

Not Reported; Not Reported; Not Reported
Not Reported; NR; NR

Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

NR; NR
Not Reported
NR; NR
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: No citations reported.

Page 419 of 522

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Asbestos	Nanomaterial Zeta	HERO ID: 3584063 Table: 1 of 1

Study Citation:	Vidovic, K., Lovrecek, B., Hraste, M. (1996). Influence of surface charge on sedimentation and filtration behaviour of fibrous material. Chemical and

Biochemical Engineering Quarterly 10(l):33-38.

OECD Harmonized Nanomaterial Zeta
Template:

HERO ID:	3584063

EXTRACTION

Parameter	Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced

Standard Deviation
pH and Medium
Results Details

-1 mV (approx) - 7.5 mV (approx)

12001-29-5; chrysotile

None; Experimental; 'a standard experimental arrangement and test procedure' citing several sources
NR; NR; NR; NR

NR; P-5-50; Ural Mines, Russia; fibrous solid; Grade 5Z (Asbestos Textile Institute (USA) and Quebec Asbestos Mining Association (Canada))
Notes: NA
9 - ca_upper

Not Reported; water; Not Reported
electrophoresis; NR; thermostated at 298K

Lab instrument contained an electroosmotic cell, membrane, Pt electrode, measuring capillary, ampmeter, voltmeter, conductometer and thermo-
stat; NA

+/-1 mV (approximate from figure)

2 to 12; Water

Approx 7.5 mV at pH 2 and -1 mV at pH 12

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.
N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Data are obtained by accepted standard analytical methods, but some details are not
reported and only cite secondary sources.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High





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Nanomaterial Zeta

HERO ID: 3531568 Table: 1 of 1

Study Citation: Wu, L., Ortiz, C. P., Jerolmack, D. J. (2017). Aggregation of Elongated Colloids in Water. Langmuir 33(2):622-629.

OECD Harmonized Nanomaterial Zeta

Template:

HERO ID: 3531568

EXTRACTION

Parameter Data

Zeta

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Isoelectric Value

Standard Deviation, Medium, and Remarks for
Isoelectric Point

Method Type, Sampling, and Additional Details
Instruments and Measurements Reproduced
Standard Deviation
pH and Medium
Results Details

ca_lower -14 - ca_upper 5.0
12001-29-5; Chrysotile
None; Experimental; NA
NA; NR; NR; NR

NA; El Dorado Mine, Salt River, Arizona; Solid block; > 90%

4-5

NR; 150 ppm (nominal) test substance in water, dispersed by sonication, pH adjusted with HC1; Dilute acid treated values in this study lower than
values reported elsewhere.

electrophoresis; NR; Zeta potential determined from electrophoretic mobility using the Smoluchowski approximation.

Delsa Nano C; NR
Not Reported

3.6, -4.4, -5.1, -5.6, -6.1, -6.9, -7.5, 8.0; 150 ppm (nominal) test substance in water, dispersed by sonication, pH adjusted with HC1

Values estimated from figure. -5.0 at pH 3.6, -2.2 at pH -4.4, —1.8 at pH -5.1, —5.7 at pH -5.6, —7.9 at pH -6.1, —12 at pH -6.9, —13 at pH

-7.5, and-14 at pH 8.0

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology was appropriate.
The analytical method was appropriate.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Data are measured for the subject chemical substance.

Overall Quality Determination

High

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Dielectric Constant

HERO ID: 7924810 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Chrysotile.
Dielectric Constant

7924810

EXTRACTION

Parameter

Data

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Dielectric Constant

Temperature

System

Results Value

Results Details

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

800-

Not Reported
Not Reported
Not Reported

at 25°C. 1 value reported in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Medium The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

* Related References: Datta; Bhattacherjee; Journal of Materials Science; vol. 21; nb. 3; (1986); p. 1041 - 1045

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Dielectric Constant

HERO ID: 7924814 Table: 1 of 1

Study Citation:
OECD Harmonized
Template:

HERO ID:

Elsevier, (2021). Reaxys: physical-chemical property data for Tremolite.
Dielectric Constant

7924814

Parameter

EXTRACTION

Data

CASRN and Test Material

Confidentiality, Type, and Guideline

Solvent, Reactivity, Storage, and Stability

Radiolabel, Source, State, and Purity

Dielectric Constant

Temperature

System

Results Value

Results Details

14567-73-8; Tremolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; Solid; NR

7.03

20 deg C
Not Reported
Not Reported

powdered tremolite at 20°C; 1 value reported in Reaxys.; monohydrated. Collected using the search term 'tremolite' in Reaxys.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1; Substance

Metric 1:
Metric 2;

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2; Test Reliability

Metric 3;

Metric 4;

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3; Other

Metric 5;
Metric 6;

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Rosenholtz, J. L.; Smith, D. T.; American Mineralogist; vol. 21; (1936); p. 115
1376 - 1378

120; Gmelin Handbuch der Anorganischen Chemie; vol. Ca: MVol.B3; 316, page

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Other Properties

HERO ID: 3827309 Table: 1 of 3

Study Citation: Addison, W. E., Neal, G. H., Sharp, J. H., White, A. D. (1966). Amphiboles. Part IV. Surface properties of amosite and crocidolite. lournal of the Chemical

Society. Section A: Inorganic, Physical, and Theoretical Chemistry 1966:79-81.

OECD Harmonized Other Properties
Template:

HERO ID: 3827309

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; lohns Manville Research Centre from leffery Mine, Quebec, CAN.; NR; NR

Results Value Surface area: 13.5 - 22.4 mA2/g @ 25°C

Results Details Not Reported

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Other Properties

HERO ID: 3827309 Table: 2 of 3

Study Citation: Addison, W. E., Neal, G. H., Sharp, J. H., White, A. D. (1966). Amphiboles. Part IV. Surface properties of amosite and crocidolite. lournal of the Chemical

Society. Section A: Inorganic, Physical, and Theoretical Chemistry 1966:79-81.

OECD Harmonized Other Properties
Template:

HERO ID: 3827309

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; Cape Asbestos Co. Ltd.; NR; NR
Surface area: 2.25 - 7.10 mA2/g @ 25°C
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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April 2024

Other Properties

HERO ID: 3827309 Table: 3 of 3

Study Citation: Addison, W. E., Neal, G. H., Sharp, J. H., White, A. D. (1966). Amphiboles. Part IV. Surface properties of amosite and crocidolite. lournal of the Chemical

Society. Section A: Inorganic, Physical, and Theoretical Chemistry 1966:79-81.

OECD Harmonized Other Properties
Template:

HERO ID: 3827309

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; Cape Asbestos Co. Ltd.; NR; NR
Surface area: 4.62 - 14.80 mA2/g @ 25°C
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Other Properties

HERO ID: 3827307 Table: 1 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter

Data

CASRN and Test Material

12172-73-5; Amosite

Confidentiality, Type, and Guideline

None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; NR; NR

Results Value

Tensile strength: 110 - 620 Mpa (16,000 -

- 90,000 lb./in.A2)

Results Details

Not Reported

Results Remarks

Not Reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured for the subject chemical substance.

Metric 2:

Appropriateness

N/A

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased

(Method Objectivity)

towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

Medium

The analytical method is unknown but is likely to be appropriate based on the data's

inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Other Properties

HERO ID: 3827307 Table: 2 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial positive parallel extinction
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Other Properties

HERO ID: 3827307 Table: 3 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial positive parallel extinction
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Other Properties

HERO ID: 3827307 Table: 4 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial ± extinction inclined
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Other Properties

HERO ID: 3827307 Table: 5 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter

Data

CASRN and Test Material

12001-29-5; Chrysotile

Confidentiality, Type, and Guideline

None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; NR; NR

Results Value

Tensile strength: 550 - 690 Mpa (80,000 -

¦ 100,000 lb./in.A2)

Results Details

Not Reported

Results Remarks

Not Reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured for the subject chemical substance.

Metric 2:

Appropriateness

N/A

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased

(Method Objectivity)

towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

Medium

The analytical method is unknown but is likely to be appropriate based on the data's

inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Other Properties

HERO ID: 3827307 Table: 6 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Tensile strength: 690 - 2100 Mpa (100,000 - 300,000 lb./in.A2)
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Other Properties

HERO ID: 3827307 Table: 7 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Mg silicate with iron
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Asbestos

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Other Properties

HERO ID: 3827307 Table: 8 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; Actinolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Ca, Mg, Fe silicate with water up to 5%
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

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Other Properties

HERO ID: 3827307 Table: 9 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite

None; Experimental; Not Reported

NR; NR; NR; NR

Luster: vitreous to pearly

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 435 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 10 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-66-4; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR
Luster: silky
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 436 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 11 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 5.5 - 6.0

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 437 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 12 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; Actinolite

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 6.0+/-

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 438 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 13 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 2.85 - 3.1

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 439 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 14 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; Actinolite

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 3.0 - 3.2

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 440 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 15 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial positive extinction parallel
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 441 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 16 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; Actinolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial negative extinction inclined
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 442 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 17 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; Anthophyllite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Tensile strength: < 30 Mpa (< 4,000 lb./in.A2)
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 443 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 18 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; Actinolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Tensile strength: < 7 Mpa (< 1,000 lb./in.A2)
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 444 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 19 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Mg silicate with some water
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 445 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 20 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Fe, Mg silicate
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 446 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 21 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Na, Fe silicate with some water
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 447 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 22 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR
Luster: silky
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 448 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 23 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Luster: vitreous to somewhat pearly
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 449 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 24 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

Luster: silky to dull

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 450 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 25 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 2.5 - 4.0

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 451 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 26 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 5.5 - 6.0

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 452 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 27 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 4.0

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 453 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 28 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 2.4 - 2.6

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 454 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 29 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 3.1 - 3.25

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 455 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 30 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 3.2 - 3.3

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 456 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 31 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-68-6; Tremolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Essential composition: Ca, Mg silicate with some water
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 457 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 32 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter Data

CASRN and Test Material 77536-68-6; Tremolite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR
Luster: silky
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 458 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827307 Table: 33 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-68-6; Tremolite

None; Experimental; Not Reported

NR; NR; NR; NR

Mohs hardness: 5.5

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 459 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 34 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-68-6; Tremolite

None; Experimental; Not Reported

NR; NR; NR; NR

Specific gravity: 2.9 - 3.2

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 460 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 35 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-68-6; Tremolite
None; Experimental; Not Reported
NR; NR; NR; NR
NR; NR; NR; NR

Optical properties: Biaxial negative extinction inclined
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 461 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3827307 Table: 36 of 36

Study Citation: Badollet, M. S. (1951). Asbestos, a mineral of unparalleled properties. Transactions, Canadian Institute of Mining and Metallurgy 54:151-160.

OECD Harmonized Other Properties

Template:

HERO ID: 3827307

EXTRACTION

Parameter

Data

CASRN and Test Material

77536-68-6; Tremolite

Confidentiality, Type, and Guideline

None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability

NR; NR; NR; NR

Radiolabel, Source, State, and Purity

NR; NR; NR; NR

Results Value

Tensile strength: 7 - 60 Mpa (1,000 -

8,000 lb./in.A2)

Results Details

Not Reported

Results Remarks

Not Reported

EVALUATION

Domain

Metric

Rating

Comments

Domain 1: Substance

Metric 1:

Representativeness

High

Data are measured for the subject chemical substance.

Metric 2:

Appropriateness

N/A

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Reliability/Unbiased

Medium

There is no indication that the methodology for producing the information was biased

(Method Objectivity)

towards a particular product or outcome.

Metric 4:

Reliability/Analytical Method

Medium

The analytical method is unknown but is likely to be appropriate based on the data's

inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:

Databases

N/A

Rating of this factor is not applicable to this kind of information.

Metric 6:

Models

N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 462 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3099513 Table: 1 of 1

Study Citation: Bartosiewicz, L. (1973). Improved Techniques of Identification and Determination of Airborne Asbestos. American Industrial Hygiene Association lournal

34(6):252-259.

OECD Harmonized Other Properties
Template:

HERO ID: 3099513

EXTRACTION

Parameter Data

CASRN and Test Material 1332-21-4; Asbestos

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; NR; NR

Results Value 2-15 um size, 12.7% particles >5 nm, average particle size 2.9 nm

Results Details Not Reported

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is non-standard but is expected to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 463 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3083760 Table: 1 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true diameter: 0.06 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 464 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3083760 Table: 2 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true diameter: 0.26 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 465 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3083760 Table: 3 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true diameter: 0.09 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 466 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3083760 Table: 4 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true length: 0.55 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 467 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3083760 Table: 5 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true length: 2.53 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 468 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3083760 Table: 6 of 6

Study Citation: Hwang, C. Y. (1983). Size and shape of airborne asbestos fibres in mines and mills. British Journal of Industrial Medicine 40(3):273-279.

OECD Harmonized Other Properties

Template:

HERO ID: 3083760

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; NR; NR

Fiber size, median true length: 1.16 nm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 469 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3970851 Table: 1 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-68-6; tremolite
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
acid resistant
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Other Properties

HERO ID: 3970851 Table: 2 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-66-4; actinolite
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
resistance to acids: none
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Other Properties

HERO ID: 3970851 Table: 3 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

77536-67-5; anthophyllite
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
resistance to acids: very
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Other Properties

HERO ID: 3970851 Table: 4 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; amosite
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
resistance to acids: somewhat
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Other Properties

HERO ID: 3970851 Table: 5 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; crocidolite
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
resistance to acids: good
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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April 2024

Other Properties

HERO ID: 3970851 Table: 6 of 6

Study Citation:

OECD Harmonized
Template:

HERO ID:

IARC, (2012). ARC Monographs on the evaluation of carcinogenic risks to humans: Asbestos (Chrysotile, amosite, crocidolite, tremolite, actinolite, and

anthophyllite).

Other Properties

3970851

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; chrysotile
none; not specified; None
NR; NR; NR; NR
None; NR; solid; NR
Fibers degrade in dilute acids
Not Reported
Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
N/A

There is no indication that the methodology for producing the information was biased

towards a particular product or outcome.

Rating of this factor is not applicable to this kind of information.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: From ATSDR (2001), USGS (2001), HSE (2005), NTP (2005)

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Asbestos

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Other Properties

HERO ID: 6865913 Table: 1 of 1

Study Citation:

OECD Harmonized
Template:

HERO ID:

Lahondfere, D., Cagnard, F., Wille, G., Duron, J., Misseri, M. (2018). TEM and FESEM characterization of asbestiform and non-asbestiform actinolite
fibers in hydrothermally altered dolerites (France). Environmental Earth Sciences 77(10):385.

Other Properties

6865913

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-67-7; Actinolite

None; Experimental; Diameter and aspect ratio; NA
NA; NR; NR; NR

NA; Saint-Salvi de Carcaves Unit and Frehel Unit in France; Solid; NR
Aspect ratio: 20:1 - 100:1, width < 0.5 fim
Analytical method: SEM-EDS-TEM-EDS
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
High

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 476 of 522

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Asbestos

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Other Properties

HERO ID: 3860485 Table: 1 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Other Properties

3860485

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Almost completely destroyed within 1 hour in IN HC1

at 95 C

Asbestos minerals, despite a relatively high fusion temperature, are completely decomposed at temperatures of 1,000 deg C.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: USEPA; Ambient Water Quality Criteria Doc: Asbestos p.A-3 (1980) EPA 440/5-80-022 (not a primary source; Primary source found in document: Lindell.
1972 Biological effects of asbestos.)

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Other Properties

HERO ID: 3860485 Table: 2 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Other Properties

3860485

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value

Results Details
Results Remarks

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Thermal decomposition is accomplished through dehydroxylation and dehydration mechanisms. Under dynamic heating conditions, dehydroxyla-
tion occurs at 650 deg C and formation of fastering and silica is apparent at 81 deg C.

Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: USEPA, Office of Drinking Water; Criteria Document (Draft): Asbestos p./l -8 (1980) (not a primary source)

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Other Properties

HERO ID: 3860485 Table: 3 of 3

Study Citation:
OECD Harmonized
Template:

HERO ID:

(2017). PubChem: Chrysotile.
Other Properties

3860485

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Not Reported

Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Not Reported; Not Reported; Not Reported; Not Reported

Completely decomposed in concentrated Potassium hydroxide.

at 200C

The resistance of the asbestos fibers to attack by reagents other than acid as excellent up to temperatures of approximately 100 deg C with rapid
deterioration observed at higher temperatures.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features

(e.g., presence of certain functional groups) or other physical/chemical properties (e.g.,
if the physical state is described as a liquid, the substance should have a melting point
below 25°C and a boiling point above 25°C) or behaviors.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

Low The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: Source: USEPA; Ambient Water Quality Criteria Doc: Asbestos p.A-5 (1980) EPA 440/5-80-022 (not a primary source; Primary source found in document)

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Other Properties

HERO ID: 3582855 Table: 1 of 1

Study Citation: Seshan, K. (1983). How are the physical and chemical properties of chrysotile asbestos altered by a 10-year residence in water and up to 5 days in simulated

stomach acid?. Environmental Health Perspectives 53(NOV):143-148.

OECD Harmonized Other Properties
Template:

HERO ID: 3582855

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile asbestos

Confidentiality, Type, and Guideline None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity No; International Union Against Cancer (UICC); National Institute of Environmental Health Sciences (NIEHS); Globe, AZ.; NR; NR

Results Value Zeta potential changed from positive to negative in < 1 hr after exposure to simulated gastric juice. Zero point charge moved from pH 6.5 for

untreated fibers to pH 4 in 0.1N HC1 treated for 5 days.

Results Details Not Reported

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
Medium

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical method is non-standard but is expected to be appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3581901 Table: 1 of 5

Study Citation: Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Environmental Research

23(2):348-361.

OECD Harmonized Other Properties
Template:

HERO ID: 3581901

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; NA; mean diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; South Africa; Solid; NR Notes: Air jet milled

Results Value Mean log width= -0.339 ± 0.229 um (width = 0.458 ± 1.69 um), log length = 1.197 ± 0.592 (length = 15.7 ± 3.91 um), mean log aspect ratio =

1.536 ±0.523

Results Details Measured by SEM

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical methods are appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3581901 Table: 2 of 5

Study Citation: Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Environmental Research

23(2):348-361.

OECD Harmonized Other Properties
Template:

HERO ID: 3581901

EXTRACTION

Parameter Data

CASRN and Test Material 12001-28-4; Crocidolite

Confidentiality, Type, and Guideline None; Experimental; None; mean diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; South Africa; Solid; NR Notes: Air jet milled

Results Value Mean log width= -0.606 ± 0.203 um (width = 0.248 ± 1.60 um), mean log length = 0.727 ± 0.442 (length = 5.33 ± 2.77 um), mean log aspect

ratio = 1.332 ± 0.426

Results Details Measured by SEM

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical methods are appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3581901 Table: 3 of 5

Study Citation:	Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Environmental Research

23(2):348-361.

OECD Harmonized Other Properties
Template:

HERO ID:	3581901

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; None; mean diameter

Solvent, Reactivity, Storage, and Stability	NA; NR; NR; NR

Radiolabel, Source, State, and Purity	NA; Idria, California; Solid; NR Notes: Short-fiber. Air classified.

Results Value	Mean log width= -0.780 ± 0.255 um (width = 0.166 ± 1.80 um) by SEM, -1.234 ± 0.251 um (width = 0.058 ± 1.78 um) by TEM, log length =

0.002 ± 0.561 (length = 1.00 ± 3.64 um) by SEM, mean log length = 0.710 ± 0.338 (length = 5.13 ± 2.18 um) by TEM; mean log aspect ratio
1.590 ± 0.383 um by SEM and 1.236 ± 0.450 um by TEM
Results Details	Measured by SEM and TEM

Results Remarks	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical methods are appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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April 2024

Other Properties

HERO ID: 3581901 Table: 4 of 5

Study Citation: Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Environmental Research

23(2):348-361.

OECD Harmonized Other Properties
Template:

HERO ID: 3581901

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; NA; mean diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Thetford, Quebec; Solid; NR Notes: Long-fiber. Air classified.

Results Value Mean log width= -0.870 ± 0.255 um (width = 0.135 ± 1.80 um), mean log length = 0.651 ± 0.619 (length = 4.48 ± 4.16 um), mean log aspect

ratio = 1.580 ± 0.383

Results Details Measured by SEM

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical methods are appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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April 2024

Other Properties

HERO ID: 3581901 Table: 5 of 5

Study Citation: Siegrist, H. G„ Wylie, A. G. (1980). CHARACTERIZING AND DISCRIMINATING THE SHAPE OF ASBESTOS PARTICLES. Environmental Research

23(2):348-361.

OECD Harmonized Other Properties
Template:

HERO ID: 3581901

EXTRACTION

Parameter Data

CASRN and Test Material 14567-73-8; Tremolite

Confidentiality, Type, and Guideline None; Experimental; NA; mean diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; St. Lawrence County, NY; Solid; NR

Results Value Mean log width= 0.117 ± 0.292 um (width = 1.31 ± 1.95 um), mean log length = 0.464 ± 0.344 (length = 2.91 ± 2.20), mean log aspect ratio =

0.347 ± 0.214

Results Details Measured by SEM and TEM

Results Remarks Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

The analytical methods are appropriate.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3615922 Table: 1 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Results Value

Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; None; mean length and diameter
NA; NR; NR; NR

NA; Personal air-monitor filters from workers involved in construction, fiber packing, cutting sheet asbestos, and crushed stone operation, operation
mill, and open pit mine; Solid; 100% chrysotile Notes: Samples prepared according to the USPHS/NIOSH filter membrane method for evaluating
airborne asbestos fibers

Mean log length = 0.031 - 0.597 fim; Mean log width = -0.630 - -1.120 fim; Mean log aspect ratio = 0.942 - 1.273; Mean length = 1.07 - 3.95
jUm; Mean width = 0.234 - 0.076 jUm; Mean aspect ratio = 8.75 - 18.7
Measured by STEM with EDXA on a particle-by-particle basis

Ranges of averages of 8 samples from different occupational or mining settings. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Other Properties

HERO ID: 3615922 Table: 2 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material 12001-29-5; Chrysotile

Confidentiality, Type, and Guideline None; Experimental; None; mean length and diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Personal air-monitor filters from workers involved in mixing fiber for cement; Solid; 92% chrysotile, 8% tremolite Notes: Samples prepared

according to the USPHS/NIOSH filter membrane method for evaluating airborne asbestos fibers
Results Value Mean log length = 0.380 jUm; Mean log width = -0.619 jUm; Mean log aspect ratio = 0.999; Mean length = 2.40 jUm; Mean width = 0.240 jUm;

Mean aspect ratio = 9.98

Results Details Measured by STEM with EDXA on a particle-by-particle basis

Results Remarks Sample from occupational setting. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3615922 Table: 3 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; None; mean length and diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Personal air-monitor filters from workers involved in vacuuming after asbestos removal; Solid; 40% amosite, 35% chrysotile, 5% gypsum,

20% other Notes: Samples prepared according to the USPHS/NIOSH filter membrane method for evaluating airborne asbestos fibers
Results Value Mean log length = 0.610 and 0.715 jUm; Mean log width = -0.654 and -0.638 jUm; Mean log aspect ratio = 1.264 and 1.353; Mean length = 4.07

and 5.19 um; Mean width = 0.222 and 0.230 um; Mean aspect ratio = 18.4 and 22.5
Results Details Measured by STEM with EDXA on a particle-by-particle basis

Results Remarks 2 samples from occupational settings. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3615922 Table: 4 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity

Results Value

Results Details
Results Remarks

12172-73-5; Amosite

None; Experimental; None; mean length and diameter
NA; NR; NR; NR

NA; Personal air-monitor filters from workers involved in insulation removal from ducting; Solid; 35% amosite, 50% chrysotile, 15% other Notes:
Samples prepared according to the USPHS/NIOSH filter membrane method for evaluating airborne asbestos fibers

Mean log length = 0.666 fim; Mean log width = -0.588 fim; Mean log aspect ratio = 1.255; Mean length = 4.63 fim; Mean width = 0.258 fim;
Mean aspect ratio = 17.99

Measured by STEM with EDXA on a particle-by-particle basis
Sample from occupational setting. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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Other Properties

HERO ID: 3615922 Table: 5 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material 12172-73-5; Amosite

Confidentiality, Type, and Guideline None; Experimental; None; mean length and diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Personal air-monitor filters from workers involved in insulation removal from ducting; Solid; 60% amosite, 20% chrysotile, 4% gypsum, 16%

other Notes: Samples prepared according to the USPHS/NIOSH filter membrane method for evaluating airborne asbestos fibers
Results Value Mean log length = 0.647 fim; Mean log width = -0.595 fim; Mean log aspect ratio = 1.242; Mean length = 4.44 fim; Mean width = 0.254 fim;

Mean aspect ratio = 17.46

Results Details Measured by STEM with EDXA on a particle-by-particle basis

Results Remarks Sample from occupational setting. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3615922 Table: 6 of 6

Study Citation: Snyder, J. G., Virta, R. L., Segreti, J. M. (1987). Evaluation of the phase contrast microscopy method for the detection of fibrous and other elongated

mineral particulates by comparison with a STEM technique. American Industrial Hygiene Association lournal 48(5):471-477.

OECD Harmonized Other Properties
Template:

HERO ID: 3615922

EXTRACTION

Parameter Data

CASRN and Test Material 13768-00-8; Actinolite

Confidentiality, Type, and Guideline None; Experimental; None; mean length and diameter

Solvent, Reactivity, Storage, and Stability NA; NR; NR; NR

Radiolabel, Source, State, and Purity NA; Personal air-monitor filters from workers involved in crushed stone operation; Solid; 100% actinolite Notes: Samples prepared according to

the USPHS/NIOSH filter membrane method for evaluating airborne asbestos fibers
Results Value Mean log length = 0.339 and 0.214 jUm; Mean log width = -0.355 and -0.476 jUm; Mean log aspect ratio = 0.695 and 0.690; Mean length = 2.18

and 1.64 jUm; Mean width = 0.442 and 0.334 jUm; Mean aspect ratio = 4.95 and 4.90
Results Details Measured by STEM with EDXA on a particle-by-particle basis

Results Remarks 2 samples from manufacturing settings. Log values were converted by reviewer.

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods.

Domain 3: Other

Metric 5: Databases High The information or data is from a recognized data collection/repository where data are

peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

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Other Properties

HERO ID: 3615789 Table: 1 of 1

Study Citation:	Thorne, P. S., Lightfoot, E. N., Albrecht, R. M. (1985). Physicochemical characterization of cryogenically ground, size separated, fibrogenic particles.

Environmental Research 36(1):89-110.

OECD Harmonized Other Properties
Template:

HERO ID:	3615789

EXTRACTION

Parameter	Data

CASRN and Test Material	12001-29-5; Chrysotile

Confidentiality, Type, and Guideline	None; Experimental; Not Reported

Solvent, Reactivity, Storage, and Stability	NR; NR; NR; NR

Radiolabel, Source, State, and Purity	No; Union Carbide Corp, CA; Monoclinic crystal; NR

Results Value	Chemical composition (ppm): 2467 Al; 678 Mn; 13.7 V; 1.1 Br; 88.4 Co; 1400 Cr; 9.69 Cs; 15380 Fe; 404 Na; 1914 Ni; 6.4 Sc; 1.20 W; 0.539

As; 3.4 Hg; 0.0176 Sm; llOZn

Results Details	Average particle size (n=50) measured by SEM: 1.00 +/- 0.44 um for Largest dimension, and 0.07 +/- 0.02 um for Smallest dimension.

Results Remarks	Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

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Other Properties

HERO ID: 3827272 Table: 1 of 2

Study Citation:

OECD Harmonized
Template:

HERO ID:

U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System
(IRIS).

Other Properties
3827272

EXTRACTION

Parameter

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12425-92-2; winchite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Optical property: pleochroism

weak to moderate: X = colorless, Y =

Not Reported

light blue—violet, Z = light blue

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

High
N/A

Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: www.minsocam.oeg/msa/HandbookAVinchite.PDF.

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Asbestos Other Properties HERO ID: 3827272 Table: 2 of 2

Study Citation: U.S. EPA, (2014). Toxicological review of libby amphibole asbestos: In support of summary information on the Integrated Risk Information System

(IRIS).

OECD Harmonized Other Properties
Template:

HERO ID: 3827272

EXTRACTION

Parameter Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

17068-76-7; richterite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

Optical property: pleochroism

weak to strong in pale yellow, orange, and red

Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured or estimated for the subject chemical substance.

High Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3: Reliability/Unbiased Medium There is no indication that the methodology for producing the information was biased

(Method Objectivity) towards a particular product or outcome.

Metric 4: Reliability/Analytical Method Low The analytical method is unknown and there is no indication that a reliable method was

used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

* Related References: www.minsocam.oeg/msa/Handbook/Winchite.PDF.

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April 2024

Other Properties

HERO ID: 6873950 Table: 1 of 2

Study Citation:

OECD Harmonized
Template:

HERO ID:

Vaillancourt, A., Denes, G., Le Van Mao, R. (1997). Reactivity of chrysotile asbestos in acids: Mechanism of transformation to silicon dioxide hemihydrate
upon leaching of magnesium. Materials Research Society Symposium Proceedings, vol. 453 :71-76.

Other Properties

6873950

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; None; Average fiber diameter
NR; NR; NR; NR

NA; Mined in Asbestos, Quebec; Solid; Commercial grade Notes: batch 7TF12
Average fiber diameter: 156 angstroms
NA
NA

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

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April 2024

Other Properties

HERO ID: 6873950 Table: 2 of 2

Study Citation:	Vaillancourt, A., Denes, G., Le Van Mao, R. (1997). Reactivity of chrysotile asbestos in acids: Mechanism of transformation to silicon dioxide hemihydrate

upon leaching of magnesium. Materials Research Society Symposium Proceedings, vol. 453 :71-76.

OECD Harmonized Other Properties
Template:

HERO ID:	6873950

EXTRACTION

Parameter	Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value

Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; Not reported; resistance to acids
NR; NR; NR; NR

NA; Mined in Asbestos, Quebec; Solid; Commercial grade Notes: batch 7TF12

Up to 1 N HC1 or H2S04, degree of crystallinity (DC) increases to 115% due to the dissolution of brucite and pyroaurite impurities (lower sample
mass and therefore higher apparent DC). Above 1 N, leaching becomes significant, and DC decreases to zero at ~7N
Minor smooth changes from acetic acid (ACA) and oxalic acid (OXA) with secondary leaching

Acid leaching of chrysotile first rapidly dissolves the basic impurities, brucite and pyroaurite; then the outer layers have "Brucite-type magnesium"
removed preferentially (no major structural reorganization); then "skeletal magnesium" is removed (structural collapse and amorphous silicon
dioxide hemihydrate is formed).

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High Data are measured for the subject chemical substance.

N/A Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:
Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

High Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use OR includes references to the original sources.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 496 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3827175 Table: 1 of 3

Study Citation:	Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized	Other Properties

Template:

HERO ID:	3827175

Parameter

Data

EXTRACTION



CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; Crocidolite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR

Zeta potential: -32 mV

Not Reported

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

Page 497 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3827175 Table: 2 of 3

Study Citation: Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized Other Properties

Template:

HERO ID: 3827175

Parameter

Data

EXTRACTION



CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; Chrysotile

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR

Zeta potential: +13.6 to +54 mV

Not Reported

Not Reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

Page 498 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3827175 Table: 3 of 3

Study Citation:	Virta, R. L. (2011). Asbestos. : 1 -40.

OECD Harmonized	Other Properties

Template:

HERO ID:	3827175

Parameter

Data

EXTRACTION



CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; Amosite

None; Experimental; Not Reported

NR; NR; NR; NR

NR; NR; NR; NR Notes: CAS in paper: Amosite [19172-73-5]
Zeta potential: -20 to -40 mV
Not Reported
Not Reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Medium

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown but is likely to be appropriate based on the data's
inclusion in a peer-reviewed/recognized database or other secondary source.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	Medium

Page 499 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 1 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

optical properties: biaxial negative oblique extinction

not reported

not reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 500 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 2 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

zeta potential: -32 (surface charge, mV); resistance to acids: good; resistance to alkalies: good
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 501 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 3 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

tensile strength: <500 MPa (to convert MPa to psi, multiply by 145)
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 502 of 522

-------
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April 2024

Asbestos	Other Properties	HERO ID: 3859385 Table: 4 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

hardness = 4.0 Mohs

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 503 of 522

-------
Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 5 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

resistance to acids: good; resistance to alkalies: good

not reported

not reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 504 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3859385 Table: 6 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

tensile strength: 1500-2600 MPa (to convert MPa to psi, multiply by 145)
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 505 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3859385 Table: 7 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-28-4; crocidolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

tensile strength: 1400-4600 MPa (to convert MPa to psi, multiply by 145)
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 506 of 522

-------
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April 2024

Asbestos	Other Properties	HERO ID: 3859385 Table: 8 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

optical properties: biaxial negative oblique extinction

not reported

not reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 507 of 522

-------
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April 2024

Asbestos	Other Properties	HERO ID: 3859385 Table: 9 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

14567-73-8; tremolite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

hardness = 5.5 Mohs

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 508 of 522

-------
Asbestos

PUBLIC RELEASE DRAFT - DO NOT CITE OR QUOTE
April 2024

Other Properties

HERO ID: 3859385 Table: 10 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

tensile strength: 1100-4400 MPa (to convert MPa to psi, multiply by 145)
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 509 of 522

-------
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April 2024

Asbestos	Other Properties	HERO II): 3859385 Table: 11 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

hardness = 5.5-6.0 Mohs

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 510 of 522

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April 2024

Asbestos	Other Properties	HERO II): 3859385 Table: 12 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

optical properties: biaxial positive-parallel extinction

not reported

not reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 511 of 522

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April 2024

Asbestos	Other Properties	HERO II): 3859385 Table: 13 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

hardness = 2.5-4.0 Mohs

not reported

not reported





Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 512 of 522

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Asbestos

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Other Properties

HERO ID: 3859385 Table: 14 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

optical properties: biaxial positive-parallel extinction

not reported

not reported



Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6:	Models	N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination	High

Page 513 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 15 of 16

Study Citation: Virta, R. L. (2004). Asbestos. 3:288-319.

OECD Harmonized Other Properties

Template:

HERO ID: 3859385

Parameter

Data

EXTRACTION

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12172-73-5; amosite

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

zeta potential: -20 to -40 (surface charge, mV); resistance to acids: fair, slowly attacked; resistance to alkalies: good
not reported
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Databases

High

The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

Metric 6: Models N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 514 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 3859385 Table: 16 of 16

Study Citation:
OECD Harmonized
Template:

HERO ID:

Virta, R. L. (2004). Asbestos. 3:288-319.
Other Properties

3859385

Parameter

EXTRACTION

Data

CASRN and Test Material
Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

12001-29-5; chrysotile

none; not specified; not specified

NR; NR; NR; NR

NR; NR; NR; NR Notes: NR

zeta potential: +13.6 to +54 (surface charge, mV); resistance to acids: weak, undergoes fairly rapid attack; resistance to alkalies: very good
chrysotile fibers tend to become negative after weathering and/or leaching
not reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
High

Data are measured or estimated for the subject chemical substance.

Measured data are consistent with the subject chemical substance structural features.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:

Metric 6:

Databases

Models

High The information or data is from a recognized data collection/repository where data are
peer-reviewed by experts in the field, are broadly available to the public for review and
use.

N/A Rating of this factor is not applicable to this kind of information.

Overall Quality Determination

High

Page 515 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 6880237 Table: 1 of 2

Study Citation: Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.

OECD Harmonized Other Properties

Template:

HERO ID: 6880237

EXTRACTION

Parameter Data

CASRN and Test Material 12172-67-7; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Gemological properties and mineral compositions of black nephrite from Guangxi

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity NR; NR; Solid; NR

Results Value Luster: Greasy to vitreous

Results Details Not Reported

Results Remarks 4 samples containing 60-99% ferro-actinolite

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured for the subject chemical substance.

Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 516 of 522

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Asbestos

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April 2024

Other Properties

HERO ID: 6880237 Table: 2 of 2

Study Citation: Zhong, Q., Liao, Z. T., Qi, L. J., Zhou, Z. Y. (2019). Black Nephrite Jade from Guangxi, Southern China. Gems & Gemology 55(2):198-215.

OECD Harmonized Other Properties

Template:

HERO ID: 6880237

EXTRACTION

Parameter Data

CASRN and Test Material 12172-67-7; Actinolite

Confidentiality, Type, and Guideline None; Experimental; Gemological properties and mineral compositions of black nephrite from Guangxi

Solvent, Reactivity, Storage, and Stability NR; NR; NR; NR

Radiolabel, Source, State, and Purity
Results Value
Results Details
Results Remarks

NR; NR; Solid; NR
Actinolite fibers were 20x0.5 jUm
Not Reported
Not Reported

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
N/A

Data are measured or estimated for the subject chemical substance.
Rating of this factor is not applicable to this kind of information.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

High
High

The methodology for producing the information is designed to answer a specific ques-
tion, and the methodology's objective is clear.

Data are obtained by accepted standard analytical methods, including, but not limited to
OECD guidelines for physical-chemical properties or other developed standard.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination High

Page 517 of 522

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Asbestos

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April 2024

Miscellaneous

HERO ID: 3646977 Table: 1 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Miscellaneous

Template:

HERO ID: 3646977

Parameter

Data

EXTRACTION

CASRN

Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Value

Temperature

System

Standard Deviation Results
Results Details

12001-29-5

none; not specified; Not reported
NR; NR; NR; NR

NR; NR; Solid; NR Notes: white asbestos; chemical formula 3MgO 2Si02 2H20

ca. 350000 lb./inch2 -

Not reported

Average tensile strength: 350000 lb./inch2

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 518 of 522

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Asbestos

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April 2024

Miscellaneous

HERO ID: 3646977 Table: 2 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Miscellaneous

Template:

HERO ID: 3646977

Parameter

Data

EXTRACTION

CASRN

Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Value

Temperature

System

Standard Deviation Results
Results Details

12172-73-5

none; not specified; Not reported
NR; NR; NR; NR

NR; NR; Solid; NR Notes: chemical formula 1.5MgO 5.5FeO 8Si02 H20

ca. 175000 lb./inch2-

Not reported

Average tensile strength: 175000 lb./inch2

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 519 of 522

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Asbestos

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April 2024

Miscellaneous

HERO ID: 3646977 Table: 3 of 3

Study Citation: Gaze, R. (1965). The Physical and Molecular Structure of Asbestos. Annals of the New York Academy of Sciences 132:23-30.

OECD Harmonized Miscellaneous

Template:

HERO ID: 3646977

Parameter

Data

EXTRACTION

CASRN

Confidentiality, Type, and Guideline
Solvent, Reactivity, Storage, and Stability
Radiolabel, Source, State, and Purity
Value

Temperature

System

Standard Deviation Results
Results Details

12001-28-4

none; not specified; Not reported
NR; NR; NR; NR

NR; NR; Solid; NR Notes: blue asbestos; chemical formula Na20 3FeO Fe203 8Si02 H20

ca. 500000 lb./inch2 -

Not reported

Average tensile strength: 500000 lb./inch2

Domain

Metric

EVALUATION

Rating

Comments

Domain 1: Substance

Metric 1:
Metric 2:

Representativeness
Appropriateness

High
Medium

Data are measured or estimated for the subject chemical substance.
Details have been omitted.

Domain 2: Test Reliability

Metric 3:

Metric 4:

Reliability/Unbiased
(Method Objectivity)
Reliability/Analytical Method

Medium
Low

There is no indication that the methodology for producing the information was biased
towards a particular product or outcome.

The analytical method is unknown and there is no indication that a reliable method was
used.

Domain 3: Other

Metric 5:
Metric 6:

Databases
Models

N/A
N/A

Rating of this factor is not applicable to this kind of information.
Rating of this factor is not applicable to this kind of information.

Overall Quality Determination Medium

Page 520 of 522

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Asbestos

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April 2024

List of Abbreviations and Acronyms for Data Quality Evaluation and Extraction Tables

List of Abbreviations and Acronyms for Data Quality Evaluation and Extraction Tables

Term

Definition

ASTM

American Society for Testing and Materials

ATSDR

Agency for Toxic Substances and Disease Registry

atm

Atmospheres

atm • m3/mol

Atmospheres - cubic meters per mole

C

Celsius

CASRN

Chemical Abstract Service registry number

CP

Centipoise

CRC

CRC Handbook of Chemistry and Physics

DOE

U.S. Department of Energy

ECB

European Chemicals Bureau

EPA

Environmental Protection Agency

F

Fahrenheit

GC

Gas Chromatography

g/cm3

Grams per cubic centimeter

GLP

Good Laboratory Practice

HLC

Henry's Law Constant

HPV

High Production Volume

HSDB

Hazard Substance Data Bank

ILO

International Labour Organization

IPCS

International Programme on Chemical Safety

IUCLID

International Uniform Chemical Information Database

K

Kelvin

Koa

Octanol-Air partition coefficient

Kow

Octanol-Water partition coefficient

mg/L

Milligrams per Liter

mol

Mole

mmHg

Millimeters of Mercury

MS

Mass Spectrometry

N/A

Not Applicable

NICNAS

National Industrial Chemicals Notification and Assessment Scheme

NLM

National Library of Medicine

NR

Not Reported

OECD

Organisation for Economic Co-operation and Development

Pa (hPa)

Pascals (hectopascals; 1 hPa =100 Pa)

pH

Negative base 10 Log of Hydrogen Ion (H+) Concentration in Aque-



ous Solution

pKa

Negative base 10 Log of Acid Dissociation Constant (Ka)

RIVM

National Institute for Public Health and the Environment (Dutch: Ri-



jksinstituut voor Volksgezondheid en Milieu)

Continued on next page ...
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Asbestos

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List of Abbreviations and Acronyms for Data Quality Evaluation and Extraction Tables

... continued from previous page

Term

Definition

RSC

Royal Society of Chemistry

RT

Retention Time

SIDs

Screening Information Dataset

VP

Vapor Pressure

US or USA

United States of America

UV (UV-Vis)

Ultra Violet (UV-Visible)

WHO

World Health Organization

Page 522 of 522

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