U.S. Environmental Protection Agency Board of Scientific Counselors
Safe and Sustainable Water Resources Subcommittee
Virtual Meeting Summary
December 1-2, December 14, 2021, and January 13, 2022

Dates and Times: December 1, 2021, 12:00 to 5:00 p.m.; December 2,

2021, 12:00 to 5:00 p.m.; December 14, 2021, 11:00 a.m. to 2:00 p.m.; January 13, 2022, 11:00
a.m. to 2:00 p.m. Eastern Time

Location: Virtual

Executive Summary

On December 1-2 and December 14, 2021, and January 13, 2022, the Environmental Protection
Agency's (EPA's) Board of Scientific Counselors (BOSC) Safe and Sustainable Water
Resources (SSWR) Subcommittee (further referred to here as the Subcommittee) convened in
virtual meetings. The goals of the two-day meeting and subsequent teleconferences were to
discuss the Office of Research and Development's (ORD) SSWR Research Program's research
areas and charge questions. The virtual meeting format allowed for presentations, open dialogue,
program feedback, Subcommittee deliberations and questions, and EPA responses to questions.

Day 1 consisted of opening remarks and introductions, presentations on Research Area 5 and
Research Area 6, and BOSC Subcommittee discussion on charge questions. Day 2 consisted of
an overview of Research Area 4, BOSC Subcommittee discussions on Charge Question 3, and
charge question breakout groups. Day 3 and 4 consisted of charge question breakout groups and
charge question report-outs.

Wednesday, December 1, 2021

Dr. Joseph Rodricks, Chair, Safe and Sustainable Water Resources Subcommittee, thanked the
Subcommittee members for their participation. He outlined the charge question assignments and
workgroups. Dr. Rodricks introduced Dr. Chris Frey, Deputy Assistant Administrator for
Science Policy, Office of Research and Development.

Dr. Frey thanked the Subcommittee for their input and feedback and emphasized the importance
BOSC Subcommittee members hold in providing external expert scientific advice. He
recognized SSWR scientists and researchers that will present later in the meeting. Dr. Frey
emphasized that the SSWR program and ORD are looking for guidance to build on the topic of
human and ecological impacts of HABs and nutrients pollution. Dr. Frey described the StRAP
for 2022-2026 is in the early stages of development and recognized EPA's BOSC substantial role
in shaping the current plan.

Safe and Sustainable Water Resources Research Program Overview and Charge Questions

Dr. Suzanne van Drunick, National Program Director, SSWR Research Program, provided an
overview of the three research areas that will be covered during the meeting. Research Area 4 is
focused on assessment and management of Harmful Algal Blooms (HABs). Research Area 5


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covers the science to support nutrient-related water quality goals, and Research Area 6 is focused
on nutrient reduction strategies and assessment. Dr. van Drunick described the three charge
questions.

Nutrients and Harmful Algal Blooms

Dr. Anne Rea, Senior Science Advisor, Nutrients and Harmful Algal Blooms Topic Lead,
Sustainable and Healthy Communities Research Program, introduced the nutrients and HABs
research topic, which aims to comprehensively address nutrient issues and HABs. Dr. Rea
described the work in Research Area 5 as research to determine nutrient-related impacts in
watersheds and water bodies across various scales, support water quality management goals, and
quantity ecosystem response and recovery rates. She noted that Research Area 6 has three broad
components of nutrient reduction strategies, including application of state of the science,
effectiveness evaluation, and whole system integrated management and engagement. Dr. Rea
emphasized that the Subcommittee meetings are an opportunity for the EPA BOSC and SSWR
program to learn about the current research efforts and how the research is designed to address
the needs of EPA and the public.

Research Area 5: Science to Support Nutrient-Related Water Quality Goals

Overview of Research Area 5: Science to Support Nutrient-Related Water Quality Goals:
Research Highlights

Dr. Heather Golden, Research Physical Scientist, Center for Environmental Measurement and
Modeling (CEMM) provided an overview of Research Area 5. She emphasized the nutrient
pollution problem has consequences for human health, environmental health, and the economy.
Dr. Golden described the goal of Research Area 5 and the three corresponding outputs as
thematic subareas. She discussed the general research approaches, including monitoring,
sediment profiles, laboratory analysis, remote sensing, and modeling. Dr. Golden described the
three research outputs and subsequent example research products within each subarea.

Research Focused on Novel Methods to Assess Nutrient Indicators

Dr. Cheryl Brown, Research Oceanographer, Center for Public Health and Environmental
Assessment (CPHEA) outlined the issue, approach, result, and subsequent research of ORD's
research on novel methods to assess nutrient impacts and indicators. She identified primary
agency drivers of their work being the Clean Water Act (CWA) and Nutrient Scientific
Technical Exchange Partnership & Support (N-STEPS) program. Dr. Brown noted efforts in
developing deoxyribonucleic acid (DNA) metabarcoding of nutrient indicator biota, which
would improve temporal monitoring of changing nutrient conditions. She emphasized
partnerships throughout their work, including Tillamook Estuaries, EPA, OW, Office of
Wetlands, the Oregon Department of Environmental Quality, Great Lakes National Program
Office, and various EPA regions, among others. In addition, Dr. Brown underscored the status of
each of the research efforts and future directions for the research methods discussed.


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Research Focused on Vulnerability and Recovery From Excess Nutrients

Dr. Kate Schofield, Ecologist, CPHEA, presented research focused on vulnerability to and
recovery from excess nutrients, where vulnerability and recovery are the two key areas
examined. She discussed how some of the projects examine factors making freshwater and
estuary systems more susceptible to excess nutrients and related stressors, and how national
nutrient inventories and modeling approaches track nutrient sources across the Great Lakes and
terrestrial-marine boundaries. Dr. Schofield emphasized other current projects study how aquatic
systems recover from eutrophication once nutrient loads begin to decline. She identified lead
researchers, partners, and future directions of the current research efforts.

Board of Scientific Counselors Discussion of Charge Question 1

Dr. Steve Weisberg read Charge Question 1. The Subcommittee engaged in discussion, with
topics including the implementation approach, specific endpoints used for indicators, the
relationship between the nutrient concentration and the endpoints, assessing endpoint criteria,
and if certain endpoints are of greater importance.

Research Area 6: Nutrient Reduction Strategies and Assessment

Dr. Ann Rea introduced Research Area 6 and introduced the first speaker, Dr. Yongping Yuan.

Overview of Research Area 6: Nutrient Reduction Strategies and Assessment: research
Highlights

Dr. Yongping Yuan, Hydrologist, CEMM, presented an overview of EPA nutrient reduction
strategies and assessments, including the products that will allow customers to plan, implement,
and track the effectiveness of nutrient reduction strategies at multiple spatial and temporal scales.
This includes watersheds drained to receiving waters potentially affected by nutrient-related
water-quality issues.

Tools and Approaches for Implementing and tracking Nutrient Reductions

Dr. Jana Compton, Ecologist, CPHEA, reviewed EPA tools for tracking nutrient reductions to
compare landscape nutrient inputs to United States water chemistry over time and combining
that data with EPA's National Nutrient Inventory. Dr. Compton also reviewed EPA toolboxes for
stable isotope indicators for nutrient pollution and use of low-cost sensors to track nutrient
reduction efforts.

Best Practices for Integrated Nutrient Management Programs

Dr. Chris Nietch, Research Ecologist, CEMM, highlighted projects that include best practices for
nutrient management programs. He also emphasized projects related to research on improving
nutrient reduction strategies, water quality credits and their partnerships, communication and
engagement with the public, and building partner relationships. Dr. Nietch briefly reviewed the


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community-driven research Partnership for Improved Nutrient Efficiency (PINE) to better
understand nitrate leaching into groundwater from agricultural practices.

Board of Scientific Counselors Discussion of Charge Question 2

Dr. Rodricks introduced Dr. Kate Lajtha and Dr. Elizabeth Fassman-Beck to review Charge
Question 2. The Subcommittee engaged in discussion, with topics including determining best
practices for current research efforts, research related to evaluating the effectiveness of nonpoint
source nutrient reductions at local and large scales, how nutrient input and output relationships
are modified by various factors, and research implementation. Discussion topics also included
future research opportunities, stakeholder engagement and collaborations, and motivations
behind current research efforts.

Public Comment

Mr. Tom Tracy, Designated Federal Officer, Office of Science Advisor, Policy, and
Engagement, shared submitted public comments. Mr. Stephen Brown, member of the Sierra
Club, asked why there has been no mention of CAFO (Concentrated Animal Feeding Operation)
waste. He noted the conventional wisdom in Ohio and Michigan is the CAFO manure is spread
on agricultural lands and also held in lagoons where the nutrients are leaking into the ground
water. This is the major source of nutrient contamination for Lake Erie.

Thursday, December 2, 2021
Welcome and Opening Remarks

Dr. Suzanne van Drunick, welcomed the participants to the meeting and provided an overview of
the research areas and topics that will be discussed during the meeting.

Research Area 4: Assessment and Management of Harmful Algal Blooms

Research Area 4: Assessment and Management of Harmful Algal Blooms: Research
Highlights

Dr. Nick Dugan, Environmental Engineer, Center for Environmental Solutions and Emergency
Response (CESER), provided an overview of HABs, including when freshwater HABs occur,
the potential of cyanobacteria to produce toxins, commonly reported cyanotoxins, and routes of
exposure. He identified legislative drivers of HABs research and highlighted program, region,
and state needs. Dr. Dugan noted there are three research subareas: assessing adverse health
outcomes from exposure to HABs, research to support managing HABs and their impacts on
ambient and drinking water and developing tools to support HABs risk characterization and
assessment. He stated that the health outcomes were divided into three research products. Dr.
Dugan described the three research products and discussed their correlation to support HABs
management. He highlighted that the research included the CyAN app as a result of collaborative


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work between EPA, the National Aeronautics and Space Administration (NASA), and the
National Oceanic and Atmospheric Administration (NOAA).

Research Focused on Harmful Algal Blooms Toxicity

Dr. Elizabeth Hilborn, Epidemiologist, CPHEA, presented research focused on work addressing
and informing HABs toxicity. She discussed health effects derived from their risk assessment
research, the results of toxicology research, and described the acute effects of microcystic
congeners using a mouse model with oral exposure and primary human hepatocytes. Dr. Hilborn
emphasized cyanobacteria effects, commonly toxin rash and skin irritation, on human skin tissue
as dermal exposure. She discussed the toxicity of aerosolized cyanotoxins and described acute
and chronic toxicity tests on aquatic organisms. Dr. Hilborn continued to discuss science
reporting on adverse observed effects. She underscored how ambient HABs are mixtures,
containing multiple cyanobacteria, other phytoplankton, and other algae and are other potentially
harmful aquatic organisms, ranging from viruses to protozoa. She stated EPA has collaborated
with the Centers for Disease Control and Prevention (CDC) on its OneHealth Harmful Algal
Blooms system to characterize HAB events and resultant human and animal illness. Dr. Hilborn
outlined the many uncertainties about routes of exposure to cyanobacteria toxins and their work
to develop methods to identify where blooms are more likely to be toxic. She further discussed
investigative efforts into Microcystis aeruginosa in ambient waters.

Research Focused on Predictive Capability and Future Forecasting

Dr. Blake Schaeffer, Research Physical Scientist, CESER, discussed building capacity to
forecast cyanobacteria HABs (cyanoHABs). He highlighted that EPA provides recommendations
for cyanotoxin concentrations in recreational and drinking water. Dr. Schaeffer discussed bloom
versus non-bloom events, describing a bloom event as any event resulting in negative
environmental or health consequences. Dr. Schaeffer discussed details of models to predict lake
photic zone temperature, novel methods DNA and ribonucleic acid (RNA) sequenced-based
characterization and functional analysis, use of high-frequency sonde to model risks in inland
reservoirs, and Ohio River risk characterization for bloom forecasting and persistence.

Board of Scientific Counselors Discussion of Charge Question 3

The Subcommittee engaged in discussions and posed questions regarding Charge Question 3,
including topics such as StRAP implementation, acquiring compounds for testing, focusing
human observation studies on underserved or disadvantaged communities, and challenges posed
by PFAS research.

Charge Question Breakout Group Reports

The Subcommittee divided into three workgroups to discuss and draft responses to the charge
questions. After group discussions, the Subcommittee reconvened and provided an overview of
their ideas and posed questions on each charge question. Dr. Stephen Weisberg provided an
overview of the discussion on Charge Question 1, stating three main challenges of the research
presented. The first area is nutrient source identification, the second area is indicators and


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endpoints used to determine nutrient issues, and the third area referred to linkages between
nutrient concentrations and endpoint inputs. Dr. Weisberg discussed ideas and questions for
Charge Question 2, including the need for a multi-pronged communication strategy and EPA's
correlation between research efforts and monitoring programs. Dr. Lucinda Johnson shared the
ideas and questions from Charge Question 3, including the complexity of diversity of toxins,
diversity of the species delivering the toxins, and the diverse affected ecosystems. She discussed
information integration, knowledge gaps, and tools for large scale bloom occurrences.

Tuesday, December 14, 2021

Workgroups Report Out and Response to Charge Questions

Dr. Weisberg reviewed the strengths, suggestions, and recommendations for Charge Question 1
and Charge Question 2. He noted the strengths of Charge Question 1 were the wide range of
indicators, which have a good range of sensitivity, and endpoint types. The workgroup suggests
more structure within research descriptions, such as a strategy document, and a need for
assessment of how their works translate across geographies and small or large systems. The
workgroup recommended enhancing the endpoint and nutrient concentration linkage. The
workgroup suggests more structure within research descriptions, such as a strategy document,
and a need for assessment of how their works translate across geographies and small or large
systems.

Dr. Weisberg noted the strengths of Charge Question 2 were the holistic approach, the range of
possible solutions being examined, and that ORD is tying it all back to a case study focusing
beyond individual technologies. The workgroup suggests focusing more on urban stormwater,
communication of a strategic study approach to scale solutions across a range of geography, and
more information on tracking systems for assessing management success. The workgroup
recommended that ORD create a communication strategy focused on lessons learned and target
audiences.

Dr. Lucinda Johnson discussed the strengths, suggestions, and recommendations for Charge
Question 3. The strengths included the current amount of HABs research and the span of work
across multiple agencies (federal, state, tribal, and local governments). The suggestions from the
workgroup were categorized into groups including toxicity testing, chronic exposure, and
threshold determination. The workgroup recommended ensuring model development and
validation captures a range of critical ecosystem types and study sites that represent different
communities with special emphasis on underserved communities.

Thursday, January 13, 2022

Workgroups Report Out and Response to Charge Question 1

Dr. Weisberg provided a summary of the Charge Question 1 draft report. He read the
Subcommittee draft strengths, suggestions, and recommendations. The strengths included
research on biological indicators rather than on underlying nutrient concentrations, the range of
indicators ORD has considered appropriate, and ORD's work over a large spatial range of


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geographical systems. The suggestion included developing a clearer strategy for assessing how
well indicators scale across systems of different sizes and geography. Dr. Weisberg read the
actionable recommendations, including creating a document describing a coherent structure for
ORD's nutrient research strategy, and organizing the list of projects based on the structure. Dr.
Suzanne van Drunick appreciated the Subcommittee's suggestions and recommendations. She
noted the strategy is something to focus on in the next strategic plan.

Workgroups Report Out and Response to Charge Question 2

Dr. Weisberg provided a summary of the Charge Question 2 draft report. He read the
Subcommittee draft strengths, suggestions, and recommendations. He noted ORD has effectively
identified two or three factors. One of the strengths is the strategy that uses a case-study
approach. Dr. Weisberg noted the three suggestions from the workgroup, including systems used
as test systems not being legacy-dominated systems, to have more work on urban systems, and to
establish a better connection between source identification research and BMP practices under
development. The workgroup recommended having a communications strategy for
communicating with managers and scientists, who can contribute to the research efforts. Dr.
Suzanne van Drunick noted given resource limitations, ORD cannot have case studies and
different scenarios. She asked if there is a useful priority, given the wide scope of nutrients
research nationally. Dr. Weisberg noted there was no priority, if there is transferability.

Workgroups Report Out and Response to Charge Question 3

Dr. Joseph Rodricks provided an overview of the Charge Question 3 draft report. He read the
Subcommittee draft strengths, suggestions, and recommendations. Dr. Lucinda Johnson noted
there was interest in ensuring inclusion of different community types and ecosystem types in
model development and activation exercises to ensure adequate representation. Dr. Suzanne van
Drunick appreciated the recommendations and noted they would be helpful for EPA moving into
the next strategic plan.


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Meeting Agenda and Other Meeting Materials

The agenda1, ch aree questions2, and other meeting materials can be accessed at:

BOSC Safe and Sustainable Water Resources Subcommittee Meeting: December 2021 1 US
EPA.

Meeting Participants

BOSC Safe and Sustainable Water Resources Subcommittee Members:

Joseph Rodricks, Chair
Robert Blanz, Vice Chair
Scott Ahl strom*

Jerad Bales*

Steve Carr*

Shahid Chaudhry*

David Cole
Joel Ducoste
Elizabeth Fassman-Beck
Fred Hitzhusen

Lucinda Johnson, BOSC Executive Committee Vice Chair

Kate Lajtha

Michelle Lorah*

John Lowenthal

Tim Verslycke*

Stephen Wei sb erg

John White

* did not attend any meetings

EPA Designated Federal Officer (DFO): Tom Tracy, Office of Science Advisor, Policy, and
Engagement

EPA Presenters:

Cheryl Brown, Office of Research and Development, Center for Public Health and
Environmental Assessment

Jana Compton, Office of Research and Development, Center for Public Health and
Environmental Assessment

Nick Dugan, Office of Research and Development, Center for Environmental Solutions
and Emergency Response

Christopher Frey, Deputy Assistant Administrator for Science Policy, Office of Research
and Development Assistant Administrator Nominee

Heather Golden, Office of Research and Development, Center for Environmental
Measurement and Modeling


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Elizabeth Hilborn, Office of Research and Development, Center for Public Health and
Environmental Assessment

Christopher Nietch, Office of Research and Development, Center for Environmental

Measurement and Modeling

Anne Rea, Senior Science Advisor for Nutrients

Blake Schaeffer, Office of Research and Development, Center for Environmental
Measurement and Modeling

Kate Schofield, Office of Research and Development, Center for Public Health and
Environmental Assessment

Suzanne van Drunick, National Program Director, Safe and Sustainable Water
Resources Research Program

Joe Williams, Principal Associate National Program Director, Safe and Sustainable
Water Resources Research Program

Yongping Yuan, Office of Research and Development, Center for Environmental
Measurement and Modeling

Other EPA Attendees:

Jason Augustine

Amalia Handler

Jenny Paul

Azadeh Azadapour-Keeley

Matt Herberling

Marguerite Pelletier

Hannah Boone

Elizabeth Hilborn

Amina Pollard

Warren Boothman

Donna Hill

Brenda Rashleigh

J. Renee Brooks

Jeff Hollister

Anne Rea

Cheryl Brown

Brandon Jarvis

Matthew Richards

Jim Carleton

Correne Jenson

Vicki Richardson

Eliodora Chamberlain

Whitney King

Caroline Ridley

Giancario Cicchetti

Karen Kleier Schrantz

Bruce Rodan

Jana Compton

Betty Kreakie

Mary Ross

Lesley D'Anglada

Taylor Lass

Marc Russell

Naomi Detenbeck

Michelle Latham

Robert Sabo

Nick Dugan

Jim Lazorchak

Blake Schaeffer

Katie Flahive

Jingrang Lu

Marie Schneider

Katherine Foreman

Cissy Ma

Kate Schofield

Chris Frey

Bob McKane

Stephen Shivers

George Gardenier

Janet Nestlerode

Nathan Smucker

Tim Gleason

Chris Nietch

Avery Tatters

Heather Golden

Autumn Oczkowski

Dana Thomas

Rick Greene

Edward Ohanian

Hale Thurston

Ann Grimm

Jacques Olivier

Julie Weitzman

Scot Hagerthey

Kate O'Mara

Allison Yackley

Gayle Hagler

Stephen Pacella

Yongping Yuan

James Hagy

James Pauer

Robert Zucker

Other Attendees:

Astrika Adams

Ciera Baird

Lara Beaven


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Stephen Brown	Grace Gusler

Adam Carpenter	Erma Leaphart

Gloria Charland	Justin McGehee

Steve Davies	Elena Mola

David Finethy	Jayme Smith

Contractor Support:

Steven Black
Canden Byrd
Leah West
Sam Whately

Justin Spangler
Steve Via
Tom Warmuth
Linda Wilson


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